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<datestamp>2017-12-21</datestamp>
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<publisher>HAL CCSD</publisher>
<title lang=en>Job strain as a risk factor for clinical depression: systematic review and meta-analysis with additional individual participant data</title>
<creator>Madsen, I. E. H.</creator>
<creator>Nyberg, S. T.</creator>
<creator>Magnusson Hanson, L. L.</creator>
<creator>Ferrie, J. E.</creator>
<creator>Ahola, K.</creator>
<creator>Alfredsson, L.</creator>
<creator>Batty, G. D.</creator>
<creator>Bjorner, J. B.</creator>
<creator>Borritz, M.</creator>
<creator>Burr, H.</creator>
<creator>Chastang, J. -F.</creator>
<creator>Graaf, R., </creator>
<creator>Dragano, N.</creator>
<creator>Hamer, M.</creator>
<creator>Jokela, M.</creator>
<creator>Knutsson, A.</creator>
<creator>Koskenvuo, M.</creator>
<creator>Koskinen, A.</creator>
<creator>Leineweber, C.</creator>
<creator>Niedhammer, I.</creator>
<creator>Nielsen, M. L.</creator>
<creator>Nordin, M.</creator>
<creator>Oksanen, T.</creator>
<creator>Pejtersen, J. H.</creator>
<creator>Pentti, J.</creator>
<creator>Plaisier, I.</creator>
<creator>Salo, P.</creator>
<creator>Singh-Manoux, A.</creator>
<creator>Suominen, S.</creator>
<creator>Havé, M., </creator>
<creator>Theorell, T.</creator>
<creator>Toppinen-Tanner, S.</creator>
<creator>Vahtera, J.</creator>
<creator>Vaananen, A.</creator>
<creator>Westerholm, P. J. M.</creator>
<creator>Westerlund, H.</creator>
<creator>Fransson, E. I.</creator>
<creator>Heikkila, K.</creator>
<creator>Virtanen, M.</creator>
<creator>Rugulies, R.</creator>
<creator>Kivimaki, M.</creator>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>Centre de recherche en épidémiologie et santé des populations (CESP) ; Université de Versailles Saint-Quentin-en-Yvelines (UVSQ) - Université Paris-Sud - Paris 11 (UP11) - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>Université Paris Est Créteil Val de Marne (Paris 12) (UPEC)</contributor>
<contributor>Danish Working Environment Research Fund</contributor>
<contributor> UK Medical Research Council [K013351]</contributor>
<contributor> Economic and Social Research Council</contributor>
<contributor> European Union NEW OSH ERA research programme</contributor>
<contributor> Finnish Work Environment Fund</contributor>
<contributor> Swedish Research Council for Working Life and Social Research</contributor>
<contributor> German Social Accident Insurance</contributor>
<contributor> Academy of Finland and NordForsk</contributor>
<contributor> Nordic Programme on Health and Welfare [75021]</contributor>
<description>International audience</description>
<source>ISSN: 0033-2917</source>
<source>EISSN: 1469-8978</source>
<source>Psychological Medicine</source>
<publisher>Cambridge University Press (CUP)</publisher>
<identifier>hal-01560152</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01560152</identifier>
<source>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01560152</source>
<source>Psychological Medicine, Cambridge University Press (CUP), 2017, 47 (8), pp.1342--1356. 〈10.1017/S003329171600355X〉</source>
<identifier>DOI : 10.1017/S003329171600355X</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1017/S003329171600355X</relation>
<identifier>PUBMED : 28122650</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/28122650</relation>
<language>en</language>
<subject lang=en>observational studies</subject>
<subject lang=en> occupational health</subject>
<subject lang=en> work stress</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Background. Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for clinical depression. Method. We identified published cohort studies from a systematic literature search in PubMed and PsycNET and obtained 14 cohort studies with unpublished individual-level data from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium. Summary estimates of the association were obtained using random-effects models. Individual-level data analyses were based on a pre-published study protocol. Results. We included six published studies with a total of 27 461 individuals and 914 incident cases of clinical depression. From unpublished datasets we included 120 221 individuals and 982 first episodes of hospital-treated clinical depression. Job strain was associated with an increased risk of clinical depression in both published [relative risk (RR) = 1.77, 95% confidence interval (CI) 1.47-2.13] and unpublished datasets (RR = 1.27, 95% CI 1.04-1.55). Further individual participant analyses showed a similar association across sociodemographic subgroups and after excluding individuals with baseline somatic disease. The association was unchanged when excluding individuals with baseline depressive symptoms (RR = 1.25, 95% CI 0.94-1.65), but attenuated on adjustment for a continuous depressive symptoms score (RR = 1.03, 95% CI 0.81-1.32). Conclusions. Job strain may precipitate clinical depression among employees. Future intervention studies should test whether job strain is a modifiable risk factor for depression.</description>
<date>2017</date>
</dc>
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