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<datestamp>2017-12-21</datestamp>
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<publisher>HAL CCSD</publisher>
<title lang=en>A Large Outbreak of Thiamine Deficiency among Illegal Gold Miners in French Guiana</title>
<creator>Mosnier, Emilie</creator>
<creator>Niemetzky, Florence</creator>
<creator>Stroot, J</creator>
<creator>Pommier de Santi, Vincent</creator>
<creator>Brousse, Paul</creator>
<creator>Guarmit, Basma</creator>
<creator>Blanchet, Denis</creator>
<creator>Ville, Muriel</creator>
<creator>Abboud, Philippe</creator>
<creator>Djossou, Félix</creator>
<creator>Nacher, Mathieu</creator>
<contributor>Unité des Maladies Infectieuses et Tropicales [Cayenne, Guyanne Française] ; Centre Hospitalier de Cayenne Andrée Rosemon</contributor>
<contributor>Département des Centres Délocalisés de Prévention et de Soins ; Centre Hospitalier de Cayenne Andrée Rosemon</contributor>
<contributor> Écosystèmes amazoniens et pathologie tropicale ; Université de Guyane (UG)</contributor>
<contributor>Direction Interarmées du Service de Santé en Guyane</contributor>
<contributor>Centre d'épidémiologie et de santé publique des armées ; Service de Santé des Armées</contributor>
<contributor>Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane) ; Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM) - CHU de Pointe-à-Pitre - Centre Hospitalier de Cayenne Andrée Rosemon - CHU de Fort de France</contributor>
<contributor>Coordination Régionale de la lutte contre le Virus de L'Immunodéficience Humaine (COREVIH Guyane) ; Centre hospitalier Andrée Rosemon (Cayenne)</contributor>
<description>International audience</description>
<source>ISSN: 0002-9637</source>
<source>American Journal of Tropical Medicine and Hygiene</source>
<publisher>American Society of Tropical Medicine and Hygiene</publisher>
<identifier>inserm-01503899</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01503899</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01503899/document</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01503899/file/2017%2C%20Mosnier%20-%20A%20Large%20Outbreak%20of%20Thiamine%20Deficiency%20among%20Illegal%20Gold%20Miners%20in%20French%20Guiana.pdf</identifier>
<source>http://www.hal.inserm.fr/inserm-01503899</source>
<source>American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2017, Epub ahead of print. 〈10.4269/ajtmh.15-0906〉</source>
<identifier>DOI : 10.4269/ajtmh.15-0906</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.4269/ajtmh.15-0906</relation>
<language>en</language>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>From September 2013 to July 2014, several gold miners working in the tropical forest consulted the Maripasoula Health Center in French Guiana for edema and findings consistent with right cardiac failure. Of the 42 cases of beriberi that were diagnosed, one patient died. The laboratory and clinical investigation demonstrated vitamin B1 deficiency in most of the patients tested. Furthermore, 30 of 42 patients responded favorably to 500 mg of intravenous or intramuscular thiamine supplementation. In addition, dietary investigation showed insufficient thiamine intake in these patients. We concluded that patients had acquired beriberi because of diet restrictions, hard labor, and infectious diseases, notably malaria. In 2016, cases were still being reported. We recommend screening for compatible symptoms in gold miners, thiamine supplementation, and nutritional intervention</description>
<date>2017-03-13</date>
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