untitled
<OAI-PMH schemaLocation=http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd>
<responseDate>2018-01-15T18:25:16Z</responseDate>
<request identifier=oai:HAL:hal-01214005v1 verb=GetRecord metadataPrefix=oai_dc>http://api.archives-ouvertes.fr/oai/hal/</request>
<GetRecord>
<record>
<header>
<identifier>oai:HAL:hal-01214005v1</identifier>
<datestamp>2017-12-21</datestamp>
<setSpec>type:ART</setSpec>
<setSpec>subject:sdv</setSpec>
<setSpec>collection:UNIV-RENNES1</setSpec>
<setSpec>collection:UNIV-AG</setSpec>
<setSpec>collection:IRSET</setSpec>
<setSpec>collection:IRSET-VCER</setSpec>
<setSpec>collection:IFR140</setSpec>
<setSpec>collection:BIOSIT</setSpec>
<setSpec>collection:UR1-UFR-SVE</setSpec>
<setSpec>collection:STATS-UR1</setSpec>
<setSpec>collection:UR1-HAL</setSpec>
<setSpec>collection:EHESP</setSpec>
<setSpec>collection:USPC</setSpec>
<setSpec>collection:UR1-SDV</setSpec>
<setSpec>collection:IRSET-8</setSpec>
<setSpec>collection:UNIV-ANGERS</setSpec>
</header>
<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=en>Linking transcriptomics and proteomics in spermatogenesis</title>
<creator>Chalmel, Frédéric</creator>
<creator>Rolland, Antoine D.</creator>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>This work was supported by the Institut national de la santé et de la recherche médicale (Inserm), the Université de Rennes 1, the Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES n°EST-13-081 to F Chalmel), the Fondation pour la recherche médicale (FRM n°DBI20131228558 to F Chalmel), and the European Union (FEDER to F Chalmel). </contributor>
<description>International audience</description>
<source>ISSN: 1470-1626</source>
<source>EISSN: 1741-7899</source>
<source>Reproduction</source>
<publisher>BioScientifica</publisher>
<identifier>hal-01214005</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01214005</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01214005/document</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01214005/file/Linking%20transcriptomics%20and%20proteomics%20in%20spermatogenesis.pdf</identifier>
<source>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01214005</source>
<source>Reproduction, BioScientifica, 2015, 150 (5), pp.R149--157. 〈10.1530/REP-15-0073〉</source>
<identifier>DOI : 10.1530/REP-15-0073</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1530/REP-15-0073</relation>
<identifier>PUBMED : 26416010</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/26416010</relation>
<language>en</language>
<subject>[SDV] Life Sciences [q-bio]</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Spermatogenesis is a complex and tightly regulated process leading to the continuous production of male gametes, the spermatozoa. This developmental process requires the sequential and coordinated expression of thousands of genes, including many that are testis-specific. The molecular networks underlying normal and pathological spermatogenesis have been widely investigated in recent decades, and many high-throughput expression studies have studied genes and proteins involved in male fertility. In this review, we focus on studies that have attempted to correlate transcription and translation during spermatogenesis by comparing the testicular transcriptome and proteome. We also discuss the recent development and use of new transcriptomic approaches that provide a better proxy for the proteome, from both qualitative and quantitative perspectives. Finally, we provide illustrations of how testis-derived transcriptomic and proteomic data can be integrated to address new questions and how the 'proteomics informed by transcriptomics' technique, by combining RNA-seq and MS-based proteomics, can contribute significantly to the discovery of new protein-coding genes or new protein isoforms expressed during spermatogenesis.</description>
<date>2015</date>
</dc>
</metadata>
</record>
</GetRecord>
</OAI-PMH>
