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<identifier>oai:HAL:hal-00715441v1</identifier>
<datestamp>2017-12-21</datestamp>
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<setSpec>subject:sdv</setSpec>
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<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=en>Comparative automated assay of anti-P1 antibodies in acute hepatic distomiasis (fascioliasis) and in hydatidosis.</title>
<creator>Ben-Ismail, R.</creator>
<creator>Rouger, P.</creator>
<creator>Carme, Bernard</creator>
<creator>Gentilini, M.</creator>
<creator>Salmon, C.</creator>
<contributor>Epidémiologie des parasitoses et mycoses tropicales ; Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<description>International audience</description>
<source>ISSN: 0042-9007</source>
<source>EISSN: 1423-0410</source>
<source>Vox Sanguinis</source>
<publisher>Wiley</publisher>
<identifier>hal-00715441</identifier>
<identifier>https://hal.univ-antilles.fr/hal-00715441</identifier>
<source>https://hal.univ-antilles.fr/hal-00715441</source>
<source>Vox Sanguinis, Wiley, 1980, 38 (3), pp.165-8</source>
<identifier>PUBMED : 7385756</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/7385756</relation>
<language>en</language>
<subject>[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>An automated assay of anti-P1 allohemagglutinins has been carried out on 133 P2 subjects: 13 with acute hepatic distomiasis (Fascioliasis), 20 with hydatidosis and 100 healthy blood donors. Anti-P1 were detected in 100% of the distomatid sera, in 50% of the hydatid and in 29% of the healthy individuals. When compared to a reference serum test (anti-P1 standard), their concentration was found to be weak in healthy subjects, moderate in hydatidosis and exceptionally increased in acute distomiasis (up to 5-6 times the standard anti-P1 level). The 2-mercaptoethanol treatment showed that even the increased distomatid anti-P1 sera were of an IgM nature. The respective origin, synthesis and strength of these allohemagglutinins are discussed and the advantages of using distomatid IgM anti-P1 as human sera test are emphasized.</description>
<date>1980</date>
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