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<datestamp>2018-01-11</datestamp>
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<publisher>HAL CCSD</publisher>
<title lang=en>Elevated Blood Lead Levels in Infants and Mothers in Benin and Potential Sources of Exposure</title>
<creator>Bodeau-Livinec, Florence</creator>
<creator>Glorennec, Philippe</creator>
<creator>Cot, Michel</creator>
<creator>Dumas, Pierre</creator>
<creator>Durand, Séverine</creator>
<creator>Massougbodji, Achille</creator>
<creator>Ayotte, Pierre</creator>
<creator>Le Bot, Barbara</creator>
<contributor>Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153) ; Université Paris Descartes - Paris 5 (UPD5) - Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A 1125)) ; Institut National de la Recherche Agronomique (INRA) - Université Sorbonne Paris Cité (USPC) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Institut National de la Recherche Agronomique (INRA) - Université Sorbonne Paris Cité (USPC) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>Département Méthodes quantitatives en santé publique (METIS) ; École des Hautes Études en Santé Publique [EHESP] (EHESP)</contributor>
<contributor>DHU Risques Et Grossesse ; Assistance publique - Hôpitaux de Paris (AP-HP) - Université Paris Descartes - Paris 5 (UPD5) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Centre National de la Recherche Scientifique (CNRS)</contributor>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>École des Hautes Études en Santé Publique [EHESP] (EHESP)</contributor>
<contributor>Facultés des sciences pharmaceutiques et biologiques</contributor>
<contributor>Mère et enfant face aux infections tropicales (MERIT - UMR_D 216) ; Université Paris Descartes - Paris 5 (UPD5) - Institut de Recherche pour le Développement (IRD)</contributor>
<contributor>Institut Hospitalier J. Cartier ; Hôpital Privé Jacques Cartier [Massy]</contributor>
<contributor>Centre d'Etude et de Recherche sur le Paludisme Associé à la Grossesse et l'Enfance (CERPAGE) (CERPAGE) ; Centre d'Etude et de Recherche sur le Paludisme Associé à la Grossesse et l'Enfance (CERPAGE)</contributor>
<contributor>Université d'Abomey Calavi</contributor>
<contributor>Département de médecine sociale et préventive (DMPS) ; Université Laval</contributor>
<contributor>Axe santé des populations et pratiques optimales en santé ; Centre de recherche du Centre Hospitalier Universitaire de Québec ; CHU Québec - CHU Québec - École de psychologie ; Université Laval - Université Laval</contributor>
<contributor>Direction de la Santé Environnementale et de la Toxicologie ; Institut >National de Santé Publique du Québec</contributor>
<description>International audience</description>
<source>ISSN: 1660-4601</source>
<source>EISSN: 1660-4601</source>
<source>International Journal of Environmental Research and Public Health</source>
<publisher>MDPI</publisher>
<identifier>hal-01296778</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01296778</identifier>
<source>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01296778</source>
<source>International Journal of Environmental Research and Public Health, MDPI, 2016, 13 (3), pp.316. 〈10.3390/ijerph13030316〉</source>
<identifier>DOI : 10.3390/ijerph13030316</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.3390/ijerph13030316</relation>
<identifier>PUBMED : 26978384</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/26978384</relation>
<language>en</language>
<subject lang=en> sub-Saharan Africa</subject>
<subject lang=en> Lead Isotopic Ratios</subject>
<subject lang=en> sources</subject>
<subject lang=en>Child</subject>
<subject lang=en> lead exposure</subject>
<subject>[SDV] Life Sciences [q-bio]</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Lead in childhood is well known to be associated with poor neurodevelopment. As part of a study on maternal anemia and offspring neurodevelopment, we analyzed blood lead level (BLL) with no prior knowledge of lead exposure in 225 mothers and 685 offspring 1 to 2 years old from Allada, a semi-rural area in Benin, sub-Saharan Africa, between May 2011 and May 2013. Blood samples were analyzed by inductively coupled plasma mass spectrometry. Environmental assessments in households and isotopic ratio measurements were performed for eight children with BLL extgreater 100 µg/L. High lead levels (BLL extgreater 50 µg/L) were found in 44% of mothers and 58% of children. The median BLL was 55.1 (interquartile range 39.2-85.0) and 46.6 (36.5-60.1) µg/L, respectively. Maternal BLL was associated with offspring's consumption of piped water and animals killed by ammunition. Children's BLL was associated with presence of paint chips in the house and consumption of animals killed by ammunition. In this population, with 98% of children still breastfed, children's BLL was highly associated with maternal BLL on multivariate analyses. Environmental measures and isotopic ratios supported these findings. Offspring may be highly exposed to lead in utero and probably via breastfeeding in addition to lead paint exposure</description>
<date>2016</date>
</dc>
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