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<publisher>HAL CCSD</publisher>
<title lang=en>Environmental and dietary exposure of young children to inorganic trace elements</title>
<creator>Glorennec, Philippe</creator>
<creator>Lucas, Jean-Paul</creator>
<creator>Mercat, Anne-Camille</creator>
<creator>Roudot, Alain-Claude</creator>
<creator>Le Bot, Barbara</creator>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>École des Hautes Études en Santé Publique [EHESP] (EHESP)</contributor>
<contributor>Laboratoire de Mathématiques de Bretagne Atlantique (LMBA) ; Centre National de la Recherche Scientifique (CNRS) - Université de Bretagne Sud (UBS) - Université de Brest (UBO)</contributor>
<contributor>Centre scientifique et technique du bâtiment ( CSTB) ; Université Paris-Est (UPE)</contributor>
<contributor>Laboratoire d'Evaluation du Risque Chimique pour le COnsommateur (LERCCO) ; Université de Brest (UBO)</contributor>
<contributor> French Ministry of Ecology (MEDDAT-SU0001768).</contributor>
<description>International audience</description>
<source>ISSN: 0160-4120</source>
<source>Environment International</source>
<publisher>Elsevier</publisher>
<identifier>inserm-01404061</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01404061</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01404061/document</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01404061/file/rev1%20-%20MS%20Expo%20metals.pdf</identifier>
<source>http://www.hal.inserm.fr/inserm-01404061</source>
<source>Environment International, Elsevier, 2016, 97, pp.28 - 36. 〈10.1016/j.envint.2016.10.009〉</source>
<identifier>DOI : 10.1016/j.envint.2016.10.009</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.envint.2016.10.009</relation>
<identifier>PUBMED : 27770708</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/27770708</relation>
<language>en</language>
<subject lang=en> Residential exposure</subject>
<subject lang=en> Public health</subject>
<subject lang=en>Aggregate exposure</subject>
<subject lang=en> Metal</subject>
<subject lang=en> Total diet study</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Children are exposed to toxic metals and metalloids via their diet and environment. Our objective was to assess the aggregate chronic exposure of children aged 3–6 years, living in France, to As, Cd, Cr, Cu, Mn, Pb, Sb, Sr, and V present in diet, tap water, air, soil and floor dust in the years 2007–2009. Dietary data came from the French Total Diet Study, while concentrations in residential tap water, soil and indoor floor dust came from the ‘Plomb-Habitat’ nationwide representative survey on children's lead exposure at home. Indoor air concentrations were assumed to be equal to outdoor air concentrations, which were retrieved from regulatory measurements networks. Human exposure factors were retrieved from literature. Data were combined with Monte Carlo simulations. Median exposures were 1.7, 0.3, 10.2, 34.1, 60.3, 0.7, 0.1, 44.3, 1.5 and 95th percentiles were 4.4, 0.5, 15.8, 61.3, 98.3, 2.5, 0.1, 111.1, 2.9 μg/kg bw/d for As, Cd, Cr, Cu, Mn, Pb, Sb, Sr, and V respectively. Dietary exposures dominate aggregate exposures, with the notable exception of Pb - for which soils and indoor floor dust ingestion contribute most at the 95th percentile. The strengths of this study are that it aggregates exposures that are often estimated separately, and uses a large amount of representative data. This assessment is limited to main diet and residential exposure, and does not take into account the relative bioavailability of compounds. These results could be used to help target prevention strategies.</description>
<date>2016-10-19</date>
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