untitled
<OAI-PMH schemaLocation=http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd>
<responseDate>2018-01-15T18:32:14Z</responseDate>
<request identifier=oai:HAL:hal-01099719v1 verb=GetRecord metadataPrefix=oai_dc>http://api.archives-ouvertes.fr/oai/hal/</request>
<GetRecord>
<record>
<header>
<identifier>oai:HAL:hal-01099719v1</identifier>
<datestamp>2018-01-11</datestamp>
<setSpec>type:ART</setSpec>
<setSpec>subject:sdv</setSpec>
<setSpec>subject:stat</setSpec>
<setSpec>collection:UNIV-RENNES1</setSpec>
<setSpec>collection:UNIV-BREST</setSpec>
<setSpec>collection:UNIV-AG</setSpec>
<setSpec>collection:CSTB</setSpec>
<setSpec>collection:CNRS</setSpec>
<setSpec>collection:UNIV-UBS</setSpec>
<setSpec>collection:MATHBREST</setSpec>
<setSpec>collection:INVS</setSpec>
<setSpec>collection:SANTE_PUB_INSERM</setSpec>
<setSpec>collection:IFR140</setSpec>
<setSpec>collection:LMBA</setSpec>
<setSpec>collection:IRSET</setSpec>
<setSpec>collection:INSERM</setSpec>
<setSpec>collection:IRSET-ERD</setSpec>
<setSpec>collection:BIOSIT</setSpec>
<setSpec>collection:UR1-UFR-SVE</setSpec>
<setSpec>collection:UBS</setSpec>
<setSpec>collection:EHESP</setSpec>
<setSpec>collection:UR1-HAL</setSpec>
<setSpec>collection:USPC</setSpec>
<setSpec>collection:UR1-SDV</setSpec>
<setSpec>collection:IRSET-9</setSpec>
<setSpec>collection:UNIV-ANGERS</setSpec>
<setSpec>collection:IRSET-EHESP</setSpec>
</header>
<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=en>Environmental determinants of different Blood Lead Levels in children: a quantile analysis from a nationwide survey.</title>
<creator>Etchevers, Anne</creator>
<creator>Le Tertre, Alain</creator>
<creator>Lucas, Jean-Paul</creator>
<creator>Bretin, Philippe</creator>
<creator>Oulhote, Youssef</creator>
<creator>Le Bot, Barbara</creator>
<creator>Glorennec, Philippe</creator>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>Institut de Veille Sanitaire (INVS) ; Institut de Veille Sanitaire (INVS)</contributor>
<contributor>Centre Scientifique et Technique du Bâtiment (CSTB)</contributor>
<contributor>LMBA_UBS ; Laboratoire de Mathématiques de Bretagne Atlantique (LMBA) ; Université de Bretagne Sud (UBS) - Université de Brest (UBO) - Centre National de la Recherche Scientifique (CNRS) - Université de Bretagne Sud (UBS) - Université de Brest (UBO) - Centre National de la Recherche Scientifique (CNRS)</contributor>
<contributor>Ministère des affaires sociales, de la santé et des droits des femmes - Direction générale de la santé</contributor>
<contributor>Université de Montréal, Montréal, Canada</contributor>
<contributor>École des Hautes Études en Santé Publique [EHESP] (EHESP)</contributor>
<description>International audience</description>
<source>ISSN: 0160-4120</source>
<source>Environment International</source>
<publisher>Elsevier</publisher>
<identifier>hal-01099719</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-01099719</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-01099719/document</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-01099719/file/Manuscript_Etchevers_EI_V3_no%20%20changes%20marked.pdf</identifier>
<source>https://hal.archives-ouvertes.fr/hal-01099719</source>
<source>Environment International, Elsevier, 2015, 74, pp.152-159. 〈10.1016/j.envint.2014.10.007〉</source>
<identifier>DOI : 10.1016/j.envint.2014.10.007</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.envint.2014.10.007</relation>
<identifier>PUBMED : 25454232</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/25454232</relation>
<language>en</language>
<subject lang=en>soil</subject>
<subject lang=en>dust</subject>
<subject lang=en>water</subject>
<subject lang=en>blood lead</subject>
<subject lang=en>lead exposure</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<subject>[STAT] Statistics [stat]</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Background: Blood Lead Levels (BLLs) have substantially decreased in recent decades in children in France. However, further reducing exposure is a public health goal because there is no clear toxicological threshold. The identification of the environmental determinants of BLLs as well as risk factors associated with high BLLs is important to update prevention strategies. We aimed to estimate the contribution of environmental sources of lead to different BLLs in children in France.Methods: We enrolled 484 children aged from 6 months to 6 years, in a nationwide cross-sectional survey in 2008-2009. We measured lead concentrations in blood and environmental samples (water, soils, household settled dusts, paints, cosmetics and traditional cookware). We performed two models: a multivariate generalized additive model on the geometric mean (GM), and a quantile regression model on the 10th, 25th, 50th, 75th and 90th quantile of BLLs. Results: The GM of BLLs was 13.8 μg/L (=1.38 µg/dL) (95% Confidence Intervals (CI): 12.7-14.9) and the 90th quantile was 25.7 μg/L (CI: 24.2-29.5). Household and common area dust, tap water, interior paint, ceramic cookware, traditional cosmetics, playground soil and dust, and environmental tobacco smoke were associated with the GM of BLLs. Household dust and tap water made the largest contributions to both the GM and the 90th quantile of BLLs. The concentration of lead in dust was positively correlated with all quantiles of BLLs even at low concentrations. Lead concentrations in tap water above 5 µg/L were also positively correlated with the GM, 75th and 90th quantiles of BLLs in children drinking tap water.Conclusions: Preventative actions must target household settled dust and tap water to reduce the BLLs of children in France. The use of traditional cosmetics should be avoided whereas ceramic cookware should be limited to decorative purposes.</description>
<date>2015-01-01</date>
<rights>info:eu-repo/semantics/OpenAccess</rights>
</dc>
</metadata>
</record>
</GetRecord>
</OAI-PMH>
