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<title lang=en>Environmental exposure assessment in European birth cohorts: results from the ENRIECO project.</title>
<creator>Gehring, Ulrike</creator>
<creator>Casas, Maribel</creator>
<creator>Brunekreef, Bert</creator>
<creator>Bergström, Anna</creator>
<creator>Bonde, Jens Peter</creator>
<creator>Botton, Jérémie</creator>
<creator>Chévrier, Cecile</creator>
<creator>Cordier, Sylvaine</creator>
<creator>Heinrich, Joachim</creator>
<creator>Hohmann, Cynthia</creator>
<creator>Keil, Thomas</creator>
<creator>Sunyer, Jordi</creator>
<creator>Tischer, Christina</creator>
<creator>Toft, Gunnar</creator>
<creator>Wickman, Magnus</creator>
<creator>Vrijheid, Martine</creator>
<creator>Nieuwenhuijsen, Mark</creator>
<contributor>Risk Assessment Sciences Institute ; Utrecht University [Utrecht]</contributor>
<contributor>Epidemiologia Ambiental ; Centre for Research in Environmental Epidemiology (CREAL) - Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP) of Pamplona - Institut Hospital del Mar d'Investigacions Mèdiques (IMIM)</contributor>
<contributor>Julius Center for Health Sciences and Primary Care ; University Medical Center Utrecht</contributor>
<contributor>Institute of Environmental Medicine ; Karolinska Institutet [Stockholm] - Sachs' Children's Hospital</contributor>
<contributor>Department of Occupational and Environmental Medicine ; Bispebjerg University Hospital</contributor>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>Helmholtz Zentrum ; Institute of Epidemiology - München & German Research Centre for Environmental Health</contributor>
<contributor>Institute of Social Medicine ; Charité University Medical Center Berlin - Epidemiology and Health Economics</contributor>
<contributor>Preventive Medicine and Public Health ; Universitat Pompeu Fabra [Barcelona]</contributor>
<contributor>Department of Occupational Medicine ; Aarhus University Hospital</contributor>
<contributor>This work was supported by ENRIECO (Environmental Health Risks in European Birth Cohorts), a project conducted within the European Union's 7th Framework Programme (Theme 6, Environment (Including Climate Change)) [Grant agreement number: 226285].</contributor>
<description>International audience</description>
<source>ISSN: 1476-069X</source>
<source>Environmental Health</source>
<publisher>BioMed Central</publisher>
<identifier>inserm-00785248</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00785248</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00785248/document</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00785248/file/1476-069X-12-8.pdf</identifier>
<source>http://www.hal.inserm.fr/inserm-00785248</source>
<source>Environmental Health, BioMed Central, 2013, 12 (1), pp.8. 〈10.1186/1476-069X-12-8〉</source>
<identifier>DOI : 10.1186/1476-069X-12-8</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1186/1476-069X-12-8</relation>
<identifier>PUBMED : 23343014</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/23343014</relation>
<language>en</language>
<subject lang=fr>Environment</subject>
<subject lang=fr>Europe</subject>
<subject lang=fr>Exposure assessment</subject>
<subject lang=fr>Birth cohort</subject>
<subject lang=fr>Review</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>ABSTRACT: Environmental exposures during pregnancy and early life may have adverse health effects. Single birth cohort studies often lack statistical power to tease out such effects reliably. To improve the use of existing data and to facilitate collaboration among these studies, an inventory of the environmental exposure and health data in these studies was made as part of the ENRIECO (Environmental Health Risks in European Birth Cohorts) project. The focus with regard to exposure was on outdoor air pollution, water contamination, allergens and biological organisms, metals, pesticides, smoking and second hand tobacco smoke (SHS), persistent organic pollutants (POPs), noise, radiation, and occupational exposures. The review lists methods and data on environmental exposures in 37 European birth cohort studies. Most data is currently available for smoking and SHS (N=37 cohorts), occupational exposures (N=33), outdoor air pollution, and allergens and microbial agents (N=27). Exposure modeling is increasingly used for long-term air pollution exposure assessment; biomonitoring is used for assessment of exposure to metals, POPs and other chemicals; and environmental monitoring for house dust mite exposure assessment. Collaborative analyses with data from several birth cohorts have already been performed successfully for outdoor air pollution, water contamination, allergens, biological contaminants, molds, POPs and SHS. Key success factors for collaborative analyses are common definitions of main exposure and health variables. Our review emphasizes that such common definitions need ideally be arrived at in the study design phase. However, careful comparison of methods used in existing studies also offers excellent opportunities for collaborative analyses. Investigators can use this review to evaluate the potential for future collaborative analyses with respect to data availability and methods used in the different cohorts and to identify potential partners for a specific research question.</description>
<date>2013-01-23</date>
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