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<publisher>HAL CCSD</publisher>
<title lang=en>Welding, a risk factor of lung cancer: the ICARE study</title>
<creator>Matrat, Mireille</creator>
<creator>Guida, Florence</creator>
<creator>Mattei, Francesca</creator>
<creator>Cenée, Sylvie</creator>
<creator>Cyr, Diane</creator>
<creator>Fevotte, Joelle</creator>
<creator>Sanchez, Marie</creator>
<creator>Menvielle, Gwenn</creator>
<creator>Radoï, Loredana</creator>
<creator>Schmaus, Annie</creator>
<creator>Woronoff, Anne-Sophie</creator>
<creator>Luce, Danièle</creator>
<creator>Stücker, Isabelle</creator>
<contributor>Unité de pathologie professionnelle ; CHI Créteil</contributor>
<contributor>Centre de recherche en épidémiologie et santé des populations (CESP) ; Université de Versailles Saint-Quentin-en-Yvelines (UVSQ) - Université Paris-Sud - Paris 11 (UP11) - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Paul Brousse - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>Epidémiologie environnementale des cancers ; Université Paris-Sud - Paris 11 (UP11) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement (UMRESTTE) ; Université Claude Bernard Lyon 1 (UCBL) - Institut National de Recherche sur les Transports et leur Sécurité (INRETS) - Institut de Veille Sanitaire (INVS)</contributor>
<contributor>Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP) ; Université Pierre et Marie Curie - Paris 6 (UPMC) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>Oral medicine and oral surgery department ; Université Paris Descartes - Paris 5 (UPD5)</contributor>
<contributor>UMS 011 ; Institut National de la Santé et de la Recherche Médicale - Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)</contributor>
<contributor>Francim : Réseau français des registres des cancers ; CHU Toulouse [Toulouse] - Hôpital Purpan [Toulouse]</contributor>
<contributor>Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (CEF2P / CARCINO) ; Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon) - Université Bourgogne Franche-Comté (UBFC) - Université de Franche-Comté (UFC)</contributor>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<description>International audience</description>
<source>Occupational and Environmental Medicine</source>
<identifier>hal-01274887</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01274887</identifier>
<source>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01274887</source>
<source>Occupational and Environmental Medicine, 2016, 73 (4), pp.254-61. 〈10.1136/oemed-2015-102964〉</source>
<identifier>DOI : 10.1136/oemed-2015-102964</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1136/oemed-2015-102964</relation>
<identifier>PUBMED : 26865654</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/26865654</relation>
<language>en</language>
<subject>[SDV] Life Sciences [q-bio]</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>OBJECTIVES: We investigated the relationship between lung cancer and occupational exposure to welding activity in ICARE, a population-based case-control study. METHODS: Analyses were restricted to men (2276 cases, 2780 controls). Welding exposure was assessed through detailed questionnaires, including lifelong occupational history. ORs were computed using unconditional logistic regression, adjusted for lifelong cigarette smoking and occupational exposure to asbestos. RESULTS: Among the regular welders, welding was associated with a risk of lung cancer (OR=1.7, 95% CI 1.1 to 2.5), which increased with the duration (OR=2.0, 95% CI 1.0 to 3.9 when duration extgreater10 years), and was maximum 10-20 years since last welding. The risk was more pronounced in case of gas welding (OR=2.0, 95% CI 1.2 to 3.3), when the workpiece was covered by paint, grease, or other substances (OR=2.0, 95% CI 1.2 to 3.4) and when it was cleaned with chemical substances before welding. No statistically significant increase in lung cancer risk was observed among occasional welders. CONCLUSIONS: Although these results should be confirmed, we showed that type of welding and mode of workpiece preparation are important determinants of the lung cancer risk in regular welders</description>
<date>2016-02</date>
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