untitled
<OAI-PMH schemaLocation=http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd>
<responseDate>2018-01-15T18:37:30Z</responseDate>
<request identifier=oai:HAL:inserm-00769338v1 verb=GetRecord metadataPrefix=oai_dc>http://api.archives-ouvertes.fr/oai/hal/</request>
<GetRecord>
<record>
<header>
<identifier>oai:HAL:inserm-00769338v1</identifier>
<datestamp>2018-01-09</datestamp>
<setSpec>type:ART</setSpec>
<setSpec>subject:sdv</setSpec>
<setSpec>collection:INSERM</setSpec>
<setSpec>collection:SANTE_PUB_INSERM</setSpec>
<setSpec>collection:UNIV-AG</setSpec>
<setSpec>collection:IFR140</setSpec>
<setSpec>collection:IRSET</setSpec>
<setSpec>collection:UNIV-RENNES1</setSpec>
<setSpec>collection:IRSET-ERD</setSpec>
<setSpec>collection:BIOSIT</setSpec>
<setSpec>collection:UR1-UFR-SVE</setSpec>
<setSpec>collection:UNIV-LORRAINE</setSpec>
<setSpec>collection:EHESP</setSpec>
<setSpec>collection:UR1-HAL</setSpec>
<setSpec>collection:USPC</setSpec>
<setSpec>collection:UR1-SDV</setSpec>
<setSpec>collection:IRSET-9</setSpec>
<setSpec>collection:UNIV-ANGERS</setSpec>
</header>
<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=en>Economic evaluation of health consequences of prenatal methylmercury exposure in France.</title>
<creator>Pichery, Céline</creator>
<creator>Bellanger, Martine</creator>
<creator>Zmirou-Navier, Denis</creator>
<creator>Fréry, Nadine</creator>
<creator>Cordier, Sylvaine</creator>
<creator>Roue-LeGall, Anne</creator>
<creator>Hartemann, Philippe</creator>
<creator>Grandjean, Philippe</creator>
<contributor>École des Hautes Études en Santé Publique [EHESP] (EHESP)</contributor>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>Département santé environnement ; Institut de Veille Sanitaire</contributor>
<contributor>Service de Santé Publique ; Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)</contributor>
<contributor>Nutrition-Génétique et Exposition aux Risques Environnementaux (NGERE) ; Institut National de la Santé et de la Recherche Médicale (INSERM) - Université de Lorraine (UL)</contributor>
<contributor>Institute of Public Health ; UNIVERSITY OF SOUTHERN DENMARK</contributor>
<contributor>Department of Environmental Health ; Harvard School of Public Health</contributor>
<description>International audience</description>
<source>ISSN: 1476-069X</source>
<source>Environmental Health</source>
<publisher>BioMed Central</publisher>
<identifier>inserm-00769338</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00769338</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00769338/document</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00769338/file/1476-069X-11-53.pdf</identifier>
<source>http://www.hal.inserm.fr/inserm-00769338</source>
<source>Environmental Health, BioMed Central, 2012, 11 (1), pp.53. 〈10.1186/1476-069X-11-53〉</source>
<identifier>DOI : 10.1186/1476-069X-11-53</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1186/1476-069X-11-53</relation>
<identifier>PUBMED : 22883022</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/22883022</relation>
<language>en</language>
<subject lang=it>Economic evaluation</subject>
<subject lang=it>Methylmercury</subject>
<subject lang=it>Prenatal exposure</subject>
<subject lang=it>Neurodevelopmental deficits</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>UNLABELLED: ABSTRACT: BACKGROUND: Evidence of a dose-response relationship between prenatal exposure to methylmercury (MeHg) and neurodevelopmental consequences in terms of IQ reduction, makes it possible to evaluate the economic consequences of MeHg exposures. OBJECTIVE: To perform an economic evaluation of annual national benefits of reduction of the prenatal MeHg exposure in France. METHODS: We used data on hair-Hg concentrations in French women of childbearing age (18-45 years) from a national sample of 126 women and from two studies conducted in coastal regions (n = 161and n = 503). A linear dose response function with a slope of 0.465 IQ point reduction per μg/g increase in hair-Hg concentration was used, along with a log transformation of the exposure scale, where a doubling of exposure was associated with a loss of 1.5 IQ points. The costs calculations utilized an updated estimate of €2008 17,363 per IQ point decrement, with three hypothetical exposure cut-off points (hair-Hg of 0.58, 1.0, and 2.5 μg/g). RESULTS: Because of higher exposure levels of women in coastal communities, the annual economic impacts based on these data were greater than those using the national data, i.e. € 1.62 billion (national), and € 3.02 billion and € 2.51 billion (regional), respectively, with the linear model, and € 5.46 billion (national), and € 9.13 billion and € 8.17 billion (regional), with the log model, for exposures above 0.58 μg/g. CONCLUSIONS: These results emphasize that efforts to reduce MeHg exposures would have high social benefits by preventing the serious and lifelong consequences of neurodevelopmental deficits in children.</description>
<date>2012</date>
</dc>
</metadata>
</record>
</GetRecord>
</OAI-PMH>