Manioc : Portail | resultats 161 - 180 pour la recherche: Martin, Georges

Journal historique de la révolution de la partie de l'est de Saint-Domingue, commencée le 10 août 1808 : avec des notes statistiques sur cette partie
Auteur(s) : Guillermin de Montpinay, Gilbert
Année de publication :

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Survival and morbidity of preterm children born at 22 through 34 weeks' gestation in France in 2011: results of the EPIPAGE-2 cohort study.
Auteur(s) : Ancel, Pierre-Yves Goffinet, François Kuhn, Pierre Langer, Bruno Matis, Jacqueline Hernandorena, Xavier Chabanier, Pierre Joly-Pedespan, Laurence
Auteurs secondaires : Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A 1125)) ; Institut National de la Recherche Agronomique (INRA) - Université Sorbonne Paris Cité (USPC) - Institut National de la Santé et de la Recherche Médicale (INSERM) Service de Gynécologie et Obstétrique [Cochin] ; Assistance publique - Hôpitaux de Paris (AP-HP) - CHU Cochin [AP-HP] Recherche Epidémiologique en Santé Périnatale et Santé des Femmes et des Enfants (UMR_S 953) ; Institut National de la Santé et de la Recherche Médicale (INSERM) - Université Paris Descartes - Paris 5 (UPD5) - Université Pierre et Marie Curie - Paris 6 (UPMC) - Université Paris-Sud - Paris 11 (UP11) Laboratoire d'Imagerie et de Neurosciences Cognitives (LINC) ; Université Louis Pasteur - Strasbourg I - IFR37 - Centre National de la Recherche Scientifique (CNRS) Service de gynécologie–obstétrique ; CHU Strasbourg - Hôpital de Hautepierre [Strasbourg] Centre de compétences des microangiopathies thrombotiques ; CHU Bordeaux [Bordeaux] pôle gynécologie-obstétrique et médecine foetale ; CHU Bordeaux [Bordeaux] Périnatalité, grossesse, Environnement, PRAtiques médicales et DEveloppement (PEPRADE) ; CHU Clermont-Ferrand - Université d'Auvergne - Clermont-Ferrand I (UdA)

Éditeur(s) : HAL CCSD
Résumé : International audience
Up-to-date estimates of the health outcomes of preterm children are needed for assessing perinatal care, informing parents, making decisions about care, and providing evidence for clinical guidelines. To determine survival and neonatal morbidity of infants born from 22 through 34 completed weeks' gestation in France in 2011 and compare these outcomes with a comparable cohort in 1997. The EPIPAGE-2 study is a national, prospective, population-based cohort study conducted in all maternity and neonatal units in France in 2011. A total of 2205 births (stillbirths and live births) and terminations of pregnancy at 22 through 26 weeks' gestation, 3257 at 27 through 31 weeks, and 1234 at 32 through 34 weeks were studied. Cohort data were collected from January 1 through December 31, 1997, and from March 28 through December 31, 2011. Analyses for 1997 were run for the entire year and then separately for April to December; the rates for survival and morbidities did not differ. Data are therefore presented for the whole year in 1997 and the 8-month and 6-month periods in 2011. Survival to discharge and survival without any of the following adverse outcomes: grade III or IV intraventricular hemorrhage, cystic periventricular leukomalacia, severe bronchopulmonary dysplasia, retinopathy of prematurity (stage 3 or higher), or necrotizing enterocolitis (stages 2-3). A total of 0.7% of infants born before 24 weeks' gestation survived to discharge: 31.2% of those born at 24 weeks, 59.1% at 25 weeks, and 75.3% at 26 weeks. Survival rates were 93.6% at 27 through 31 weeks and 98.9% at 32 through 34 weeks. Infants discharged home without severe neonatal morbidity represented 0% at 23 weeks, 11.6% at 24 weeks, 30.0% at 25 weeks, 47.5% at 26 weeks, 81.3% at 27 through 31 weeks, and 96.8% at 32 through 34 weeks. Compared with 1997, the proportion of infants surviving without severe morbidity in 2011 increased by 14.4% (P < .001) at 25 through 29 weeks and 6% (P < .001) at 30 through 31 weeks but did not change appreciably for those born at less than 25 weeks. The rates of antenatal corticosteroid use, induced preterm deliveries, cesarean deliveries, and surfactant use increased significantly in all gestational-age groups, except at 22 through 23 weeks. The substantial improvement in survival in France for newborns born at 25 through 31 weeks' gestation was accompanied by an important reduction in severe morbidity, but survival remained rare before 25 weeks. Although improvement in survival at extremely low gestational age may be possible, its effect on long-term outcomes requires further studies. The long-term results of the EPIPAGE-2 study will be informative in this regard.
ISSN: 2168-6211

hal-01258705
http://hal.univ-brest.fr/hal-01258705
PUBMED : 25621457
DOI : 10.1001/jamapediatrics.2014.3351

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