Éditeur(s) : HAL CCSD Wiley/Blackwell
Résumé : 4 pages
International audience
This article documents the addition of 268 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Alburnoides bipunctatus, Chamaerops humilis, Chlidonias hybrida, Cyperus papyrus, Fusarium graminearum, Loxigilla barbadensis, Macrobrachium rosenbergii, Odontesthes bonariensis, Pelteobagrus vachelli, Posidonia oceanica, Potamotrygon motoro, Rhamdia quelen, Sarotherodon melanotheron heudelotii, Sibiraea angustata, Takifugu rubripes, Tarentola mauritanica, Trimmatostroma sp. and Wallago attu. These loci were cross-tested on the following species: Alburnoides fasciatus, Alburnoides kubanicus, Alburnoides maculatus, Alburnoides ohridanus, Alburnoides prespensis, Alburnoides rossicus, Alburnoides strymonicus, Alburnoides thessalicus, Alburnoides tzanevi, Carassius carassius, Fusarium asiaticum, Leucaspius delineatus, Loxigilla noctis dominica, Pelecus cultratus, Phoenix canariensis, Potamotrygon falkneri, Trachycarpus fortune and Vimba vimba.
ISSN: 1755-098X

hal-00823716
https://hal.archives-ouvertes.fr/hal-00823716
DOI : 10.1111/1755-0998.12095
PUBMED : 23521844

Éditeur(s) : Springer
Résumé : Series of sensitivity tests were performed with a z-coordinate, global eddy-permitting (1/4 degrees) ocean/sea-ice model (the ORCA-R025 model configuration developed for the DRAKKAR project) to carefully evaluate the impact of recent state-of-the-art numerical schemes on model solutions. The combination of an energy-enstrophy conserving (EEN) scheme for momentum advection with a partial step (PS) representation of the bottom topography yields significant improvements in the mean circulation. Well known biases in the representation of western boundary currents, such as in the Atlantic the detachment of the Gulf Stream, the path of the North Atlantic Current, the location of the Confluence, and the strength of the Zapiola Eddy in the south Atlantic, are partly corrected. Similar improvements are found in the Pacific, Indian, and Southern Oceans, and characteristics of the mean flow are generally much closer to observations. Comparisons with other state-of-the-art models show that the ORCA-R025 configuration generally performs better at similar resolution. In addition, the model solution is often comparable to solutions obtained at 1/6 or 1/10 degrees resolution in some aspects concerning mean flow patterns and distribution of eddy kinetic energy. Although the reasons for these improvements are not analyzed in detail in this paper, evidence is shown that the combination of EEN with PS reduces numerical noise near the bottom, which is likely to affect current-topography interactions in a systematic way. We conclude that significant corrections of the mean biases presently seen in general circulation model solutions at eddy-permitting resolution can still be expected from the development of numerical methods, which represent an alternative to increasing resolution.
Ocean Dynamics (1616-7341) (Springer), 2006-12 , Vol. 56 , N. 5-6 , P. 543-567

Droits : © Springer 2006. Part of Springer Science+Business Media
http://archimer.ifremer.fr/doc/2006/publication-3514.pdf
DOI:10.1007/s10236-006-0082-1
http://archimer.ifremer.fr/doc/00000/3514/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The Miradouro da Lua cliffs, which are 60 km south of Luanda, record the building and uplift of the late Neogene Palaeo-Cuanza delta. The detailed study of the sedimentary architecture and stacking pattern permitted separation of the pile into five depositional units bounded by erosional surfaces and characterised by separate facies associations (genetic sequences = units in this paper). At the base of the series, aeolian deposits (Unit 1) mark the development of a possible coastal desert during the late Miocene aridification. The major Pliocene sea-level rise (Transgressive Systems Tract) led to the drowning of the continental platform into a discrete shoreface-foreshore sequence (Unit 2), followed by an expanded deltaic sequence (Unit 3) that represents the main outcrop of the area. The sedimentary fabric of this prograding wedge during the Highstand Systems Tract reveals laterally stacked pluri-hectometic mouth bars built by the abrupt switching of a bird-foot delta during the Pliocene highstand. The clinoforms are deeply incised by submarine gullies filled both by periodic river-driven turbidite and tidal currents (Unit 4) during the coeval growing of the delta. The topset of the prograding wedge and associated gullies infill is truncated by an overall erosional unconformity that marks the widespread development of an extensive braid-delta system (Unit 5) during the lower Pleistocene sea-level drop (Lowstand Systems Tract). The last 6 m of the Braid-delta unit is overprinted by a ferallitic profile, forming the surface of the plateau and indicating long-term subaerial exposure and weathering processes consistent with the maximum warming of the middle to late Pleistocene interglacial periods. The successive abrupt shifts of the depositional systems through the sedimentary pile indicate a high-amplitude sea level amplified by major coastal uplifts and the reorganisation of the fluvial network. In this context, the palaeo-Cuanza prograding wedge signals the westward tilting and 60 m total uplift of the coastal plain during the Pliocene. A new uplift pulse by differential tilt and slope increase is deduced from the widespread development of the braid-delta complex during the early Pleistocene. The last tectonic event corresponds to the 80- to 100-m uplift and ferallitic paedogenesis during the middle to late Pleistocene interglacial stages.
ISSN: 0899-5362

hal-01053716
https://hal.archives-ouvertes.fr/hal-01053716
DOI : 10.1016/j.jafrearsci.2014.01.013

Éditeur(s) : HAL CCSD Oxford University Press
Résumé : International audience
Enhancers are developmentally controlled transcriptional regulatory regions whose activities are modulated through histone modifications or histone variant deposition. In this study, we show by genome-wide mapping that the newly discovered deoxyribonucleic acid (DNA) modification 5-hydroxymethylcytosine (5hmC) is dynamically associated with transcription factor binding to distal regulatory sites during neural differentiation of mouse P19 cells and during adipocyte differentiation of mouse 3T3-L1 cells. Functional annotation reveals that regions gaining 5hmC are associated with genes expressed either in neural tissues when P19 cells undergo neural differentiation or in adipose tissue when 3T3-L1 cells undergo adipocyte differentiation. Furthermore, distal regions gaining 5hmC together with H3K4me2 and H3K27ac in P19 cells behave as differentiation-dependent transcriptional enhancers. Identified regions are enriched in motifs for transcription factors regulating specific cell fates such as Meis1 in P19 cells and PPARγ in 3T3-L1 cells. Accordingly, a fraction of hydroxymethylated Meis1 sites were associated with a dynamic engagement of the 5-methylcytosine hydroxylase Tet1. In addition, kinetic studies of cytosine hydroxymethylation of selected enhancers indicated that DNA hydroxymethylation is an early event of enhancer activation. Hence, acquisition of 5hmC in cell-specific distal regulatory regions may represent a major event of enhancer progression toward an active state and participate in selective activation of tissue-specific genes.
ISSN: 0305-1048

inserm-00716879
http://www.hal.inserm.fr/inserm-00716879
http://www.hal.inserm.fr/inserm-00716879/document
http://www.hal.inserm.fr/inserm-00716879/file/nar.gks595.full.pdf
DOI : 10.1093/nar/gks595

Éditeur(s) : HAL CCSD American Geophysical Union - AGU
Résumé : without
InterRidge News

hal-00464150
https://hal.archives-ouvertes.fr/hal-00464150

Éditeur(s) : HAL CCSD MDPI
Résumé : International audience
Lead in childhood is well known to be associated with poor neurodevelopment. As part of a study on maternal anemia and offspring neurodevelopment, we analyzed blood lead level (BLL) with no prior knowledge of lead exposure in 225 mothers and 685 offspring 1 to 2 years old from Allada, a semi-rural area in Benin, sub-Saharan Africa, between May 2011 and May 2013. Blood samples were analyzed by inductively coupled plasma mass spectrometry. Environmental assessments in households and isotopic ratio measurements were performed for eight children with BLL extgreater 100 µg/L. High lead levels (BLL extgreater 50 µg/L) were found in 44% of mothers and 58% of children. The median BLL was 55.1 (interquartile range 39.2-85.0) and 46.6 (36.5-60.1) µg/L, respectively. Maternal BLL was associated with offspring's consumption of piped water and animals killed by ammunition. Children's BLL was associated with presence of paint chips in the house and consumption of animals killed by ammunition. In this population, with 98% of children still breastfed, children's BLL was highly associated with maternal BLL on multivariate analyses. Environmental measures and isotopic ratios supported these findings. Offspring may be highly exposed to lead in utero and probably via breastfeeding in addition to lead paint exposure
ISSN: 1660-4601

hal-01296778
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01296778
DOI : 10.3390/ijerph13030316
PUBMED : 26978384