Éditeur(s) :
HAL CCSD Résumé : International audience
Systemic Antifungal therapy (SAT) of invasive candidiasis (IC) needs to be started immediately upon clinical suspicion. Controversies exist then about potential harms from antifungal de-escalation (DE).(1) in cases of documented IC, early DE to fluconazole is recommended by US guidelines but discouraged in EU guidelines. in non-documented IC, no data are available to guide SAT DE. These questions are key issues however as the relationship between antifungal use and Candida antifungal resistance has been repeatedly demonstrated.
Intensive Care Medicine Experimental
hal-01334073
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01334073 DOI : 10.1186/2197-425X-3-S1-A5
PUBMED : 27290057