Résumé : Written on recto: "Un antiguo cruce de ferrocarril. Pinar del Río. An old Railway Gate."
CHC5017
Pinar del Río (Cuba)

Droits : http://merrick.library.miami.edu/digitalprojects/copyright.html
chc50170006070001001
1515

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
The Cathedral of Saint John the Divine, reconstructed in the 1840s, is an Antiguan landmarked located in the island’s capital Saint John’s. This Anglican Cathedral is part of the Diocese of the North East Caribbean and Aruba. In this image is the south gate of the church featuring statues of Saint John the Baptist and Saint John the Divine which were erected in 1789. Below the statue of Saint John the Divine is a woman crouched down resting her elbowing on a box. In the distance are Cathedral’s twin towers. One of the towers features a clock.
Antigua and Barbuda -- Caribbean region -- Saint John's, Antigua

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@ucf.edu
CFM1972_01a
Sheet 1:20
http://ufdc.ufl.edu/AA00028352/00001

Résumé : Digitized with funding from the Digital Library of the Caribbean grant awarded by TICFIA.
South America -- Aruba -- Fundacion Salba Nos Burico
Caribbean

Droits : Copyright, Erich Kesse, 2008. May be used in accord with Creative Commons license allowing Attribution + Noncommercial + ShareAlike (by-nc-sa).

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
A man looking at a wooden gate in a residential neighborhood. This residential street is bordered by concrete walls. Slide labeled Nassau Mar .'46.
Bahamas -- North America -- New Providence Island

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 16:4
http://ufdc.ufl.edu/AA00029445/00001

North America -- Puerto Rico -- Puerto Rico -- San Juan -- San Juan -- Fortaleza de San Juan
Caribbean

Droits : 2007, Erich Kesse - CC: at-nc-sa (Creative Commons license requiring attribution, prohibiting commercial uses, and requiring rights-share for use of this image.)

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
Typical of the upper class homes in the area, most of which had gated communities. There are various bushes and trees throughout the yard that serve as decorations.
Cuba -- Caribbean region

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 27: 19
http://ufdc.ufl.edu/CA01200438/00001

Éditeur(s) : Carey, Lea & Blanchard. J. Cochrane and co. Carey, Lea & Blanchard. ( Philadelphia ) J. Cochrane and co. ( London )
Résumé : From Wikipedia (March 23, 2013) http://en.wikipedia.org/wiki/Richard_Robert_Madden : Richard Robert Madden (born Dublin, Ireland 22 August 1798, died Dublin, 5 February 1886) was an Irish doctor, writer, abolitionist and historian of the United Irishmen. He was born at Wormwood Gate, Dublin to Edward Madden, a silk manufacturer. He was educated at private schools. He studied medicine in Paris, Italy, and St George's Hospital, London. While in Naples he became acquainted with Lady Blessington and her circle.[1] Madden was employed in the British civil service from 1833, first as a justice of the peace in Jamaica, where he was one of six Special Magistrates sent to oversee the eventual liberation of Jamaica's slave population, according to the terms of the Slavery Abolition Act 1833. From 1835 he was Superintendent of the freed Africans in Havana. His son, Thomas More Madden, who later became a surgeon and writer, was born there. In 1839 he became the investigating officer into the slave trade on the west coast of Africa, in 1847 the secretary for the West Australian colonies. He returned to Dublin and in 1850 he was named secretary of the Office for Loan Funds in Dublin.[2] He died at his home in Booterstown, just south of Dublin city, in 1886 and is interred in Donnybrook Cemetery.
Early Caribbean literature and history.

Droits : See Google and Hathi Trust statements.
18826401
http://ufdc.ufl.edu/AA00014503/00001

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. They are organized by geographical location.
Two-story yellow house with white gate and yellow concrete fence. Tall coconut trees in the yard.
Haiti -- Caribbean region
Haiti
Haiti
Haiti

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 57:7
http://ufdc.ufl.edu/CA01200280/00001

North America -- Puerto Rico -- Puerto Rico -- San Juan -- San Juan -- Cementerio Santa Maria Magdalena de Parssi
Caribbean

Droits : 2007, Erich Kesse - CC: at-nc-sa (Creative Commons license requiring attribution, prohibiting commercial uses, and requiring rights-share for use of this image.)

Éditeur(s) : HAL CCSD American Physiological Society
Résumé : Full text: http://jn.physiology.org/content/88/3/1475
International audience
The contribution of voltage-gated calcium channels (VGCC) to the development of cultured embryonic cockroach brain neurons was assessed using pharmacological agents. VGCC currents were recorded using the patch-clamp technique and were found to be blocked dose-dependently by micromolar concentrations of mibefradil. The activation and inactivation properties of the calcium channels enable a sizeable calcium current to flow at rest (about -30 and -20 mV in high-potassium culture media). As expected, the cytoplasmic-free calcium concentration was found to rise when the extracellular potassium concentration was raised from 3 to 15 and 30 mM. The effects of VGCC blockers and calcium chelators were different in fresh and in mature cultures in which the neurons were connected to each other to form a defined network. In fresh cultures, the two non-selective VGCC blockers (verapamil and mibefradil) induced a dose-dependent cell death that was proportional to their blocking effect on I(Ba). This effect could not be prevented by addition of fetal calf serum to the culture medium. A similar effect was obtained using intra- or extracellular calcium chelating agents (10 microM BAPTA-AM or 10 mM EGTA). Quite unexpectedly, blockade of the P/Q-like (omega-Aga WA-sensitive) component of the calcium current by 500 nM of omega-AgaTx IVA had no lethal effect, suggesting that the corresponding channels are not involved in the survival mechanism. As expected from their lack of effect on I(Ba), isradipine, nifedipine, and omega-CgTx GVIA did not induce cell death. When the neurons started growing neurites, their sensitivity to calcium channel blockade by mibefradil decreased, indicating a correlation between neurite outgrowth and resistance to calcium depletion. In mature cultures, the neurons became resistant to mibefradil, verapamil, and BAPTA-AM. However, these agents, as well as omega-AgaTx IVA, had a significant inhibitory effect on the increase in diameter of the connectives that linked adjacent clusters of neurons. This effect has been shown to result, in the case of mibefradil, from an inhibition of neurite outgrowth characterized by a significant reduction of the number of primary neurites and secondary branchings but not to a significant modification of the diameter of individual neurites. These results support the view that, as in vertebrates, calcium influx through VGCC plays an important role in survival and neurite outgrowth of cultured embryonic insect neurons. The differential contribution of the P/Q-like and R-like (omega-Aga WA-sensitive) calcium channels in these processes is discussed.
ISSN: 0022-3077

hal-00982287
https://hal.archives-ouvertes.fr/hal-00982287
DOI : 10.1152/jn.00749.2001
PUBMED : 12205168

North America -- Puerto Rico -- Puerto Rico -- San Juan -- San Juan -- Castillo San Cristobal
Caribbean

Droits : 2007, Erich Kesse - CC: at-nc-sa (Creative Commons license requiring attribution, prohibiting commercial uses, and requiring rights-share for use of this image.)

Éditeur(s) : HAL CCSD Elsevier
Résumé : Remerciements :- Dr. Jacques Delabie- Andrea Yockey-Dejean- Geoff Brown- Jean-Pierre Andrieu
Background: Most ant venoms consist predominantly of small linear peptides, although some contain disulfide linked peptides as minor components. However, in striking contrast to other ant species, some Anochetus venoms are composed primarily of disulfide-rich peptides. In this study, we investigated the venom of the ant Anochetus emarginatus with the aim of exploring these novel disulfide-rich peptides.Methods: The venom peptidome was initially investigated using a combination of reversed-phase HPLC and mass spectrometry, then the amino acid sequences of the major peptides were determined using a combination of Edman degradation and de novo MS/MS sequencing. We focused on one of these peptides, U-1-PONTX-Ae1a (Ae1a), because of its novel sequence, which we predicted would form a novel 3D fold. Ae1a was chemically synthesized using Fmoc chemistry and its 3D structure was elucidated using NMR spectroscopy. The peptide was then tested for insecticidal activity and its effect on a range of human ion channels.Results: Seven peptides named poneritoxins (PONTXs) were isolated and sequenced. The three-dimensional structure of synthetic Ae1a revealed a novel, compact scaffold in which a C-terminal beta-hairpin is connected to the N-terminal region via two disulfide bonds. Synthetic Ae1a reversibly paralyzed blowflies and inhibited human L-type voltage-gated calcium channels (Ca(v)1).Conclusions: Poneritoxins from Anochetus emarginatus venom are a novel class of toxins that are structurally unique among animal venoms.General significance: This study demonstrates that Anochetus ant venoms are a rich source of novel ion channel modulating peptides, some of which might be useful leads for the development of biopesticides.
ISSN: 0304-4165

hal-01511987
https://hal.archives-ouvertes.fr/hal-01511987
https://hal.archives-ouvertes.fr/hal-01511987/document
https://hal.archives-ouvertes.fr/hal-01511987/file/2016_Touchard_Biochimica_Biophysica_%7B4B3BE6A3-AE83-4C6E-B678-BBFB5CC84AF7%7D.pdf
DOI : 10.1016/j.bbagen.2016.07.027

North America -- Puerto Rico -- Puerto Rico -- San Juan -- San Juan -- Cementerio Santa Maria Magdalena de Parssi
Caribbean

Droits : 2007, Erich Kesse - CC: at-nc-sa (Creative Commons license requiring attribution, prohibiting commercial uses, and requiring rights-share for use of this image.)

Éditeur(s) : HAL CCSD Humana Press
Résumé : International audience
The sodium-proton exchanger 1 (NHE-1) is a membrane transporter that exchanges Na(+) for H(+) ion across the membrane of eukaryotic cells. It is cooperatively activated by intracellular protons, and this allosteric regulation is modulated by the biophysical properties of the plasma membrane and related lipid environment. Consequently, NHE-1 is a mechanosensitive transporter that responds to osmotic pressure, and changes in membrane composition. The purpose of this study was to develop the relationship between membrane surface tension, and the allosteric balance of a mechanosensitive transporter such as NHE-1. In eukaryotes, the asymmetric composition of membrane leaflets results in a difference in surface tensions that is involved in the creation of a reservoir of intracellular vesicles and membrane buds contributing to buffer mechanical constraints. Therefore, we took this phenomenon into account in this study and developed a set of relations between the mean surface tension, membrane asymmetry, fluid phase endocytosis and the allosteric equilibrium constant of the transporter. We then used the experimental data published on the effects of osmotic pressure and membrane modification on the NHE-1 allosteric constant to fit these equations. We show here that NHE-1 mechanosensitivity is more based on its high sensitivity towards the asymmetry between the bilayer leaflets compared to mean global membrane tension. This compliance to membrane asymmetry is physiologically relevant as with their slower transport rates than ion channels, transporters cannot respond as high pressure-high conductance fast-gating emergency valves.
ISSN: 1085-9195

inserm-00871709
http://www.hal.inserm.fr/inserm-00871709
http://www.hal.inserm.fr/inserm-00871709/document
http://www.hal.inserm.fr/inserm-00871709/file/art_3A10.1007_2Fs12013-012-9340-7.pdf
DOI : 10.1007/s12013-012-9340-7

Éditeur(s) : HAL CCSD
Résumé : International audience
Millimeter waves (MMW) will be increasingly used for future wireless telecommunications. Previous studies on skin keratinocytes showed that MMW could impact the mRNA expression of Transient Receptor Potential cation channel subfamily Vanilloid, member 2 (TRPV2). Here, we investigated the effect of MMW exposure on this marker, as well as on other membrane receptors such as Transient Receptor Potential cation channel subfamily Vanilloid, member 1 (TRPV1) and purinergic receptor P2X, ligand-gated ion channel, 3 (P2 × 3). We exposed the Neuroscreen-1 cell line (a PC12 subclone), in order to evaluate if acute MMW exposures could impact expression of these membrane receptors at the protein level. Proteotoxic stress-related chaperone protein Heat Shock Protein 70 (HSP70) expression level was also assessed. We used an original high-content screening approach, based on fluorescence microscopy, to allow cell-by-cell analysis and to detect any cell sub-population responding to exposure. Immunocytochemistry was done after 24 h MMW exposure of cells at 60.4 GHz, with an incident power density of 10 mW/cm2. Our results showed no impact of MMW exposure on protein expressions of HSP70, TRPV1, TRPV2, and P2 × 3. Moreover, no specific cell sub-populations were found to express one of the studied markers at a different level, compared to the rest of the cell populations. However, a slight insignificant increase in HSP70 expression and an increase in protein expression variability within cell population were observed in exposed cells, but controls showed that this was related to thermal effect. Bioelectromagnetics. 37:444–454, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Bioelectromagnetics

hal-01371963
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01371963
DOI : 10.1002/bem.21995
PUBMED : 27483046

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Voltage-gated calcium currents are important for the survival and growth of embryonic cockroach brain neurons in primary culture. In the present experiments, we have studied, using the patch-clamp technique, the evolution with time in culture of the voltage-dependency and of the pharmacological properties of the calcium conductance of these neurons during the formation of a network. We have observed a progressive increase of the high-voltage-activated calcium conductance and a 10mV shift of the voltage-dependency of activation towards more negative potentials. The proportion of the R-like calcium current component increased during network formation. At the same time, the highly omega-AgaTxIVA-sensitive P-like component of the current is progressively replaced by a component which is less sensitive to the toxin. The origin and functional implications of these modifications are discussed.
ISSN: 0304-3940

hal-00982273
https://hal.archives-ouvertes.fr/hal-00982273
DOI : 10.1016/j.neulet.2004.05.002
PUBMED : 15246554