Manioc : Portail | resultats 1 - 19 pour la recherche: Canal Guitton

Canal Guitton avant réfection, et à sec,après rétablissement des eaux le 16 Février 1931
Auteur(s) : Direction Générale des Travaux Publics

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Mémoire pour le chef de brigade Magloire Pélage et pour les habitants de la Guadeloupe chargés par cette colonie de l'administration provisoire après le départ du capitaine général dans le mois de brumaire an X T.2
Auteur(s) : Frasans, Hippolyte de (1768-18..) Langloys, Jean-Thomas (1746-1804)
Année de publication :

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Mémoire pour le chef de Brigade Magloire Pélage et pour les habitants de la Guadeloupe. Tome second
Auteur(s) : Frasans, Hippolyte de (1768-18..) Langloys, Jean-Thomas (1746-1804)
Année de publication :

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On the Use of Doppler Shift for Sea Surface Wind Retrieval From SAR
Auteur(s) : Mouche, Alexis Collard, Fabrice Chapron, Bertrand Dagestad, Knut-frode Guitton, Gilles Johannessen, Johnny A. Kerbaol, Vincent Hansen, Morten Wergeland

Éditeur(s) : Ieee-inst Electrical Electronics Engineers Inc
Résumé : The synthetic aperture radar (SAR) Doppler centroid has been used to estimate the scatter line-of-sight radar velocity. In weak to moderate ocean surface current environment, the SAR Doppler centroid is dominated by the directionality and strength of wave-induced ocean surface displacements. In this paper, we show how this sea state signature can be used to improve surface wind retrieval from SAR. Doppler shifts of C-band radar return signals from the ocean are thoroughly investigated by colocating wind measurements from the ASCAT scatterometer with Doppler centroid anomalies retrieved from Envisat ASAR. An empirical geophysical model function (CDOP) is derived, predicting Doppler shifts at both VV and HH polarization as function of wind speed, radar incidence angle, and wind direction with respect to radar look direction. This function is used into a Bayesian inversion scheme in combination with wind from a priori forecast model and the normalized radar cross section (NRCS). The benefit of Doppler for SAR wind retrieval is shown in complex meteorological situations such as atmospheric fronts or low pressure systems. Using in situ information, validation reveals that this method helps to improve the wind direction retrieval. Uncertainty of the calibration of Doppler shift from Envisat ASAR hampers the inversion scheme in cases where NRCS and model wind are accurate and in close agreement. The method is however very promising with respect of future SAR missions, in particular Sentinel-1, where the Doppler centroid anomaly will be more robustly retrieved.
Ieee Transactions On Geoscience And Remote Sensing (0196-2892) (Ieee-inst Electrical Electronics Engineers Inc), 2012-07 , Vol. 50 , N. 7 , P. 2901-2909

Droits : 2012 IEEE
http://archimer.ifremer.fr/doc/00088/19896/17554.pdf
DOI:10.1109/TGRS.2011.2174998
http://archimer.ifremer.fr/doc/00088/19896/

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Differential analysis of glioblastoma multiforme proteome by a 2D-DIGE approach.
Auteur(s) : Collet, Brigitte Guitton, Nathalie Saikali, Stephan Avril, Tony Pineau, Charles Hamlat, Abderrahmane Mosser, Jean Quillien, Véronique
Auteurs secondaires : Service de Biologie ; CRLCC Eugène Marquis (CRLCC) Plateforme Protéomique-Biogenouest (PPB) ; Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) - Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) - Proteomics Core Facility (Protim) ; Université de Rennes 1 (UR1) - Plateforme Génomique Santé Biogenouest® - Plateforme Génomique Santé Biogenouest® Service d'anatomie et cytologie pathologiques [Rennes] ; Université de Rennes 1 (UR1) - Hôpital Pontchaillou - CHU Pontchaillou [Rennes] Institut de Génétique et Développement de Rennes (IGDR) ; Université de Rennes 1 (UR1) - IFR140 - Centre National de la Recherche Scientifique (CNRS) This work was supported by PRIR grants, and was conducted with facilities of the High-Throughput Proteomics Platform Biogenouest (Rennes) and Histopathological Platform (Rennes I University).

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
UNLABELLED: ABSTRACT: BACKGROUND: Genomics, transcriptomics and proteomics of glioblastoma multiforme (GBM) have recently emerged as possible tools to discover therapeutic targets and biomarkers for new therapies including immunotherapy. It is well known that macroscopically complete surgical excision, radiotherapy and chemotherapy have therapeutic limitations to improve survival in these patients. In this study, we used a differential proteomic-based technique (2D-Difference Gel Electrophoresis) coupled with matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry to identify proteins that may serve as brain tumor antigens in new therapeutic assays. Five samples of patients presenting a GBM and five samples of microscopically normal brain tissues derived from brain epileptic surgery specimen were labeled and run in 2D-PAGE (Two-Dimensional Polyacrylamide Gel Electrophoresis) with an internal pool sample on each gel. Five gels were matched and compared with DIA (Difference In-gel Analysis) software. Differential spots were picked, in-gel digested and peptide mass fingerprints were obtained. RESULTS: From 51 protein-spots significantly up-regulated in GBM samples, mass spectrometry (MS) identified twenty-two proteins. The differential expression of a selected protein set was first validated by western-blotting, then tested on large cohorts of GBM specimens and non-tumor tissues, using immunohistochemistry and real-time RT-PCR. CONCLUSIONS: Our results confirmed the importance of previously described proteins in glioma pathology and their potential usefulness as biological markers but also revealed some new interesting targets for future therapies.
ISSN: 1477-5956

inserm-00585020
http://www.hal.inserm.fr/inserm-00585020
http://www.hal.inserm.fr/inserm-00585020/document
http://www.hal.inserm.fr/inserm-00585020/file/1477-5956-9-16.pdf
DOI : 10.1186/1477-5956-9-16

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