Éditeur(s) : HAL CCSD
Résumé : Les dossiers thématiques d'Agropolis, n° 11
Dans le contexte actuel de contraintes climatiques et socioéconomiques, les agricultures des zones sèches doivent évoluer afin de s’adapter et de répondre à un double défi : produire plus pour satisfaire les besoins alimentaires importants de populations en croissance, mais aussi produire mieux de façon viable et durable. Pour cela, les agricultures de ces zones doivent évoluer vers des modes de production à la fois plus productifs, économes en ressources naturelles et résistants aux aléas climatiques.Dans ce cadre, l’ingénierie écologique propose de nouvelles alternatives de gestion des systèmes agro-sylvo-pastoraux caractéristiques des régions arides et semi-arides d’Afrique subsaharienne. Ceci implique de maitriser la complexité des systèmes étudiés et de s’inspirer à la fois du fonctionnement des écosystèmes naturels de référence à la région agroécologique concernée — les savanes pour les zones sèches ouest-africaines — et des pratiques traditionnelles et savoir-faire locaux issus d’une longue adaptation face aux contraintes environnementales.À partir des expériences ouest-africaines notamment, différentes options pratiques sont exposées dans ce dossier. On pourra ainsi agir sur la biodiversité des organismes, que ce soit les plantes ou les microorganismes du sol par exemple, favoriser le recyclage des matières organiques et des éléments nutritifs pour les plantes qui sont associées, maitriser les cycles de l’eau et, enfin, agir sur l’organisation des paysages pour favoriser un meilleur contrôle des ravageurs de culture.Cependant, développer une telle approche demande une vision intégrée du fonctionnement et de l’évolution des systèmes agro-sylvo-pastoraux. Les questions sociales — le foncier, l’urbanisation et les migrations — et économiques — les marchés des denrées de première nécessité, la pauvreté, etc. — sont des déterminants essentiels qu’il convient de prendre en compte pour le développement durable des populations dans les zones sèches en Afrique subsaharienne.
https://hal.archives-ouvertes.fr/hal-01585038

hal-01585038
https://hal.archives-ouvertes.fr/hal-01585038

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Few studies have investigated the influence of environmental conditions on the within-treevariation in Eucalyptus wood traits. The genotype and environment effects and their interactionsinfluence the wood properties. Their evaluations are crucial to estimate the genotype values andto select with efficiency. Thus, the aim of this study was to better understand the effect ofground slope and wind speed on the spatial variation of basic density (ρ), stiffness (MOE) andmicrofibril angle (MFA) of Eucalyptus wood. Wood discs cut along the trunk were sampledfrom 150 six-year-old Eucalyptus grandis x E. urophylla hybrids growing in 3 contrastinggrowing conditions influenced by ground slope and wind regime. Near Infrared (NIR)calibrations previously developed for ρ, MOE and MFA were used to predict in our discs. 2-Dplots presenting the spatial variation of predicted wood traits were compared. The higher theground slope, the greater the magnitude of radial variation in ρ, principally in the medium zoneof the trunk. The spatial variation of wood stiffness seems to be sensitive to two environmentalconditions. The MFA radial decreases were more pronounced where the wind speed was higher.At the base and top of the trees, however, there was no significant effect of growing conditionson the radial variation of the wood properties considered here.
ISSN: 0931-1890

hal-01451896
https://hal.archives-ouvertes.fr/hal-01451896
https://hal.archives-ouvertes.fr/hal-01451896/document
https://hal.archives-ouvertes.fr/hal-01451896/file/Art_Gril_al_Spatial_variation_wood_density_2016.pdf
DOI : 10.1007/s00468-015-1327-8

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
OBJECTIVES:Blood rheology plays a key role in the pathophysiology of sickle cell anaemia (SS) and sickle cell haemoglobin C disease (SC), but its evolution over the lifespan is unknown.MATERIALS AND METHODS:Blood viscosity, red blood cell (RBC) deformability and aggregation, foetal haemoglobin (HbF) and haematocrit were measured in 114 healthy individuals (AA), 267 SS (161 children + 106 adults) and 138 SC (74 children + 64 adults) patients.RESULTS:Our results showed that 1) RBC deformability is at its maximal value during the early years of life in SS and SC populations, mainly because HbF level is also at its peak, 2) during childhood and adulthood, hydroxycarbamide treatment, HbF level and gender modulated RBC deformability in SS patients, independently of age, 3) blood viscosity is higher in older SS and SC patients compared to younger ones and 4) haematocrit decreases as SS patients age.CONCLUSION:The hemorheological changes detected in older patients could play a role in the progressive development of several chronic disorders in sickle cell disease, whose prevalence increases with age. Retarding these age-related haemorheological impairments, by using suitable drugs, may minimize the risks of vaso-occlusive events and chronic disorders.
ISSN: 1932-6203

Droits : http://creativecommons.org/licenses/by/
hal-01669747
https://hal.univ-antilles.fr/hal-01669747
DOI : 10.1371/journal.pone.0158182
PUBMED : 27355589
PUBMEDCENTRAL : PMC4927160

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
BACKGROUND:Sickle cell anaemia (SCA) is a severe hereditary haemoglobinopathy characterised by haemorheological abnormalities, which play a role in the occurrence of several acute and chronic clinical complications. While βS -haplotypes and alpha-thalassaemia modulate SCA clinical severity, their effects on blood rheology have been incompletely described. The aim of this study was to test the effects of these genetic modifiers on the haemorheological properties and clinical complication of children with SCA.PROCEDURE:Steady-state haemorheological profile, biological parameters, βS -haplotypes, alpha-globin status, vaso-occlusive crisis (VOC) and acute chest syndrome frequencies were analysed in 128 children (aged 5 to 18 years) with SCA.RESULTS:Patients with alpha-thalassaemia showed increased red blood cell (RBC) deformability and aggregation compared to those without. Median VOC rate was higher in patients with homozygous alpha-thalassaemia compared to those with a normal alpha genotype. Conversely, the haemorheological profile and clinical complications were not influenced by the βS -haplotypes in our study.CONCLUSION:Our results demonstrate that alpha-thalassaemia is associated with higher risk for VOC events in children with SCA, which may be due in part to its effects on RBC deformability and aggregation.
ISSN: 1545-5009

hal-01668317
https://hal.univ-antilles.fr/hal-01668317
DOI : 10.1002/pbc.26455
PUBMED : 28097791