Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This paper proposes a new approach for the on-site detection of micropollutants in water in case of accidental or intentional contamination (characterized by high concentration). The technique is based on the use of an automatic multiple solid phase extraction step (MSPE) followed by direct or indirect UV spectrometry (MSPE/UV) for the detection of organic contaminants in water (such as regulated molecules (pesticides ...) as well as emerging pollutants (pharmaceutical products, endocrine disruptors ...)). The development of the system supposes firstly the choice of the most appropriate sorbent(s) and secondly conditions for the detection of targeted micropollutants, from several solid phase extraction cartridges and eluting solvents. Two different extraction sorbents were chosen. These sorbents and several eluting solvents allow the first separation of the compounds based on the physico-chemical properties of each substance (pKa, log Kow) and on the specific interactions with the sorbent. Finally, a UV analysis (either at the maximum of absorbance using a calibration curve or from the whole spectrum using a multicomponent (deconvolution) exploitation method) of each fraction allows a determination and a quantification of each compound. The method is rapid (less than 2 h), sensitive enough for an accidental/intentional contamination (between 5 and 40 μg*L− 1 according to the substances) and with a good precision (between 4 and 14%).
ISSN: 0026-265X

hal-00878024
https://hal.archives-ouvertes.fr/hal-00878024
DOI : 10.1016/j.microc.2012.10.025

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
An inter-laboratory exercise was organized under the PHARMAS EU project, by the Advanced School of Public Health (EHESP), in order to evaluate the performances of analytical methods for the measurement of antibiotics in waters (surface and tap). This is the first time such an exercise on antibiotics has been organized in Europe, using different kinds of analytical methods and devices. In this exercise thirteen laboratories from five countries (Canada, France, Italy, the Netherlands and Portugal) participated, and a total number of 78 samples were distributed. During the exercise, 2 testing samples (3 bottles of each) prepared from tap water and river water, respectively, spiked with antibiotics, were sent to participants and analyzed over a period of one month. A final number of 77 (98.7%) testing samples were considered. Depending on substances studied by each participant, 305 values in duplicate were collected, with the results for each sample being expressed as the target concentration. A statistical study was initiated using 611 results. The mean value, standard deviation, coefficient of variation, standard uncertainty of the mean, median, the minimum and maximum values of each series as well as the 95% confidence interval were obtained from each participant laboratory. In this exercise, 36 results (6% of accounted values) were outliers according to the distribution over the median (box plot). The outlier results were excluded. In order to establish the stability of testing samples in the course of the exercise, differences between variances obtained for every type of sample at different intervals were evaluated. The results showed no representative variations and it can be considered that all samples were stable during the exercise. The goals of this inter-laboratory study were to assess results variability when analysis is conducted by different laboratories, to evaluate the influence of different matrix samples, and to determine the rate at which participating laboratories successfully completed the tests initiated.
Talanta

hal-00878118
https://hal.archives-ouvertes.fr/hal-00878118
DOI : 10.1016/j.talanta.2012.06.064
PUBMED : 22939142

Éditeur(s) : HAL CCSD
Résumé : International audience
Environmental context The safeguarding of water supplies and drinking water is a major issue when considering human health risk management. In this context, an automatic and on-site fractionation system for the detection of organic contaminants has been developed. The main goal of this system is to establish an initial diagnosis by identifying a class of substances involved in a case of pollution. Abstract This paper proposes a new approach for the preconcentration, fractionation, prediction and detection of organic micropollutants in water. The main aim of this study was to implement an innovative fractionation method and a prediction model based on the physicochemical properties of compounds and interactions with the sorbent of solid-phase extraction cartridges. Two sorbents (Strata-SAX and Oasis-HLB) and three specific eluting solvents (mixture of methanol and sodium chloride and mixtures of acetonitrile and ultrapure water) were used to separate organic compounds into five specific fractions according to their physicochemical properties (anionic and cationic or neutral compounds with various polarity). More than 75 molecules (43 molecules individually studied and a mixture with 43 molecules, including 11 molecules individually studied) including pesticides, pharmaceuticals, endocrine disruptors and polycyclic aromatic hydrocarbons, with various properties were studied, and the results showed that the elution fraction can be predicted for more than 85% of the compounds. This methodology could simplify the analytical chain by reducing detailed analysis on limited categories of compounds, and could be used for a rapid and on-site screening of organic compounds. © CSIRO 2016.
Environmental Chemistry

hal-01373945
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01373945
DOI : 10.1071/EN15135