Éditeur(s) : HAL CCSD
Résumé : International audience
A 6 mg./kg. daily dose of levamisole was given during three days to ten carriers of microfilarias Wuchereria bancrofti in Tahiti. No action against adult worms was noticed. The immediate microfilaricid action was at least equivalent to the action of DEC. However the decrease of microfilaremia was not so long with levamisole than with DEC given to a lower dose. Lastly the amount of reactions after a treatment by levamisole is notable.
Bull Soc Pathol Exot Filiales

hal-00715413
https://hal.univ-antilles.fr/hal-00715413
PUBMED : 1037387

Éditeur(s) : HAL CCSD
Résumé : International audience
The authors analyze the data concerning 219 sera, that they have tested in passive hemagglutination, with as antigen a Dirofilaria immitis proteic extract, in French Polynesia. Besides its light sensitivity, this method does appear very interesting. It points out: --First, that there is a gaussian distribution of the results found at various dilutions, both by "filarian" and "non filarian" people. Therefore, this distribution is a feasible and practical parameter for evaluation of the Filariasis transmission in different populations. --On the other hand, that there is an inverse correlation between the presence of microfilaria in the blood and the level of immunological response for lymphatic Filariasis.
Bull Soc Pathol Exot Filiales

hal-00715412
https://hal.univ-antilles.fr/hal-00715412
PUBMED : 1037386

Éditeur(s) : HAL CCSD
Résumé : International audience
In French Polynesia the cases of leprosy are individually severe, like in Asia, but the endemy always stood under a relatively low level. A strong campaign of chemiotherapy has been conducted for 25 years. Unfortunatly the actions of systematic detection of new cases are not sufficient and the sanitary education is almost non existent. The territory is actualy reached by deep demographic and social upsettings and chemiotherapy used alone is not enough efficient to obtain a definitive decrease of the endemy or even to avoid, for a long time, a new increase. However a significant decrease of the age of advent of the decrease must be credited to the action of chemiotherapy.
Bull Soc Pathol Exot Filiales

hal-00715415
https://hal.univ-antilles.fr/hal-00715415
PUBMED : 1037614

Éditeur(s) : HAL CCSD
Résumé : International audience
Realized in French Polynesia among 274 patients with elephantiasis, this survey studied the microfilaremia, the eosinophily, the immunoglobulin titers and the antifilarian antibodies (done by passive hemagglutination) for Wuchereria bancrofti var. pacifica. Patients with elephantiasis seldom have circulating microfilariae in their blood. Hypereosinophily is frequent but rarely high. It is similar to the one patients with microfilaremia. There is a trend towards neutropenia during lymphangitic crisis that occur on an elephantiasis limb. The IgE titer is clearly increased, the IgG one is lesser elevated. The mean values are identical to those encoutered among microfilariae asymptomatic cariers. On the other hand the serodiagnosis is more frequently positive among elephantiasic patients.
Bull Soc Pathol Exot Filiales

hal-00715424
https://hal.univ-antilles.fr/hal-00715424
PUBMED : 385164

Éditeur(s) : HAL CCSD
Résumé : International audience
The authors compare the serological results obtained before and after a single dose with diethylcarbamazine (6 mg./kg.) in a homogeneous and strongly infected with Wuchereria bancrofti var, pacifica population. They point out a statistically significant decrease of the hemagglutining antibody titres of filarian patients.
Bull Soc Pathol Exot Filiales

hal-00715414
https://hal.univ-antilles.fr/hal-00715414
PUBMED : 1037437

Éditeur(s) : HAL CCSD
Résumé : International audience
An important hypereosinophilia is usually regarded as an interesting argument of presumption in lymphatic filariasis. This present report concerns 278 Polynesians people infected with Wuchereria bancrofti pacifica. Six kinds of patients were analysed: carriers of microfilarias, patients with elephantiasis, with lymphangitis attacks, new infections, carriers of microfilariasis recently treated with Diethylcarbamazine and, at least, 100 fellows without filariasis. The results which were observed differ, in some aspects, from the usually admitted ideas.
Bull Soc Pathol Exot Filiales

hal-00715417
https://hal.univ-antilles.fr/hal-00715417
PUBMED : 1037617