Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Miocene (17-11 Ma) magmatic activity in the Kabylies emplaced K-rich (and minor medium-K) calc-alkaline plutonic and volcanic rocks in five zones, delineating a ∼450 km long EW trending strip located along the northern coast of Algeria, between Annaba and Algiers. Their most likely source is the Kabylian subcontinental lithospheric mantle previously metasomatized during the Paleogene subduction of the Tethys oceanic lithosphere. Our preferred tectono-magmatic model involves a Tethyan slab detachment combined with African mantle delamination and crustal stacking, leading to the superimposition of the African continental crust over the Kabylian metasomatized lithospheric mantle. At ca. 17 Ma, the asthenospheric upwelling arising from lithospheric delamination and Tethyan slab tear triggered the thermal erosion of the latter mantle, inducing its partial melting. The corresponding mafic medium-K calc-alkaline magmas interacted with the African basement units during their ascent, generating intermediate to felsic K-rich calc-alkaline melts that display a characteristic trace element and isotopic crustal signature. Later on, slab tears propagated eastward and westward, promoting slab rollback perpendicular to plate convergence and inducing the emplacement of magmatic rocks of decreasing ages from central-eastern Algeria towards Tunisia and Morocco.
ISSN: 0899-5362

hal-01467997
https://hal.archives-ouvertes.fr/hal-01467997
DOI : 10.1016/j.jafrearsci.2016.10.005

Éditeur(s) : HAL CCSD Landes Bioscience
Résumé : International audience
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
Autophagy

hal-00735751
https://hal.archives-ouvertes.fr/hal-00735751
PUBMED : 22966490

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Volumetrically minor microsyenites, alkali microgranite and related trachytic dykes intrude early Pliocene OIB-like alkali basaltic and basanitic flows of the Meseta del Lago Buenos Aires in Central Patagonia (47 degrees S-71 degrees 30'W), and occur together with scarce trachytic lava flows. Whole-rock K-Ar ages between 3.98 and 3.08 Ma indicate that the emplacement of these felsic rocks occurred more or less synchronously with that of the post-plateau basaltic sequence that they intrude, during a bimodal mafic-felsic magmatic episode devoid of intermediate compositions. Chemically, these rocks have A(1)-type granitoid affinities and are characterized by high silica and alkali contents (60-68 wt.% SiO2; 8.7-10.8 wt.% Na2O+K2O), major and trace elements patterns evidencing evolution by low-pressure fractional crystallization, and Sr and Nd isotopic signatures similar to those of coeval basalts ((Sr-87/Sr-86)o=0.70488-0.70571; (Nd-143/Nd-144)(o)=0.512603-0.512645). Nevertheless, some of them have the most radiogenic Sr values ever reported for a magmatic rock in the Meseta and even in the whole Neogene Patagonian Plateau Lavas province ((Sr-17/Sr-86)(o)= 0.70556-0.70571; (Nd-143/Nd-144)(o)=0.512603-0.512608). In addition, very high contents of strongly incompatible elements in the most evolved rocks, together with Sr isotopic ratios higher than those of coeval basalts, suggest the occurrence of open-system magmatic processes. Continuous fractional crystallization from a primitive basaltic source, similar to post-plateau coeval basalts, towards alkali granites combined with small rates of assimilation of host Jurassic tuffs (AFC) in a shallow magmatic reservoir, best explains the geochemical and petrographic features of the felsic rocks. Therefore, A(1)-type magmatic rocks can be generated by open-system crystallization of deep asthenospheric melts in back-are tectonic settings. In Central Patagonia, these similar to 3-4 Ma old alkaline intrusions occur aligned along a similar to N160-170 trending lineament, the Zeballos Fault Zone, stacking the morphotectonic front of one segment of the Patagonian Cordillera. Intrusion along this fault zone
ISSN: 0024-4937

hal-00412030
https://hal.archives-ouvertes.fr/hal-00412030
DOI : 10.1016/j.lithos.2007.07.002

Éditeur(s) : HAL CCSD Wiley-VCH Verlag
Résumé : International audience
Deciphering the assembly history of the Milky Way is a formidable task, which becomes possible only if one can produce high-resolution chrono-chemo-kinematical maps of the Galaxy. Data from large-scale astrometric and spectroscopic surveys will soon provide us with a well-defined view of the current chemo-kinematical structure of the Milky Way, but will only enable a blurred view on the temporal sequence that led to the present-day Galaxy. As demonstrated by the (ongoing) exploitation of data from the pioneering photometric missions CoRoT, Kepler, and K2, asteroseismology provides the way forward: solar-like oscillating giants are excellent evolutionary clocks thanks to the availability of seismic constraints on their mass and to the tight age-initial-mass relation they adhere to. In this paper we identify five key outstanding questions relating to the formation and evolution of the Milky Way that will need precise and accurate ages for large samples of stars to be addressed, and we identify the requirements in terms of number of targets and the precision on the stellar properties that are needed to tackle such questions. By quantifying the asteroseismic yields expected from PLATO for red-giant stars, we demonstrate that these requirements are within the capabilities of the current instrument design, provided that observations are sufficiently long to identify the evolutionary state and allow robust and precise determination of acoustic-mode frequencies. This will allow us to harvest data of sufficient quality to reach a 10% precision in age. This is a fundamental pre-requisite to then reach the more ambitious goal of a similar level of accuracy, which will only be possible if we have to hand a careful appraisal of systematic uncertainties on age deriving from our limited understanding of stellar physics, a goal which conveniently falls within the main aims of PLATO's core science.
ISSN: 0004-6337

hal-01541393
https://hal.archives-ouvertes.fr/hal-01541393
ARXIV : 1706.3778
BIBCODE : 2017AN....338..644M
DOI : 10.1002/asna.201713385

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This study presents new geochemical data on 26 mafic lavas from the Middle Atlas and Central Morocco volcanic provinces, including Miocene nephelinites and Pliocene-Quaternary (3.9-0.6Ma) nephelinites, basanites, alkali and subalkaline basalts. Most of them represent near-primary magmas, although some alkali basalts were derived from the minor fractionation of olivine and diopside phenocrysts. These evolved samples and the subalkaline basalt display higher 207Pb/204Pb and Zr/Nb ratios and lower εNd consistent with their contamination by lower crustal granulites during an open fractionation process. The progressive enrichment in incompatible elements observed from alkali basalts to nephelinites suggests their derivation from decreasing partial melting degrees of an enriched mantle source located at the garnet-spinel transition zone. The strong negative spikes observed for K in multielement patterns indicate that this source contained a residual pargasitic amphibole. We propose that partial melting occurred at around 2GPa, i.e. near the lithosphere-asthenosphere boundary beneath the Middle Atlas (60-80km).The trace element and isotopic Sr-Nd-Pb-Hf signature of the uncontaminated lavas displays a geochemical flavour intermediate between those of high μ (HIMU), "C", and enriched mantle components. It is very similar to that of abundant metasomatic amphibole- and clinopyroxene-rich lithospheric peridotites and pyroxenites carried by Middle Atlas lavas, which likely represent an analog of the source of these lavas. It is therefore not necessary to postulate the contribution of a "fresh" asthenospheric mantle to their genesis. We propose that they resulted from the partial melting of the base of a veined lithospheric mantle metasomatised during the late Cretaceous by alkaline melts from the Central Atlantic plume, the ancestor of the Canary plume. Melting was probably triggered by the flux of a hot mantle within a regional SW-NE sub-lithospheric channel, in response to either the Alboran slab retreat or edge-driven convection around the West African craton.
ISSN: 0024-4937

insu-01056523
https://hal-insu.archives-ouvertes.fr/insu-01056523
DOI : 10.1016/j.lithos.2014.07.009

Éditeur(s) : HAL CCSD
Résumé : National audience
The Lesser Antilles subduction zone has produced no recent strong thrust earthquakes, making it difficult to quantify the seismic hazard from such events. The Lesser Antilles arc has a low subduction rate and an accretionary wedge that is very wide at its southern end. To investigate the effect of the wedge on seismogenesis, numerical models of forearc thermal structure were constructed along six transects perpendicular to the arc in order to determine the thermally predicted width of the seismogenic zone. The geometry of each section is constrained by published seismic profiles and crustal models derived from gravity and seismic data and by earthquake hypocenters at depth. A major constraint on the deep part of the model is that mantle temperature beneath the volcanic arc should achieve a temperature of 1,100°C to generate partial melts. Predicted surface heat flow is compared to the available heat flow observations. Thermal modeling results indicate a systematic southward increase in the width of the seismogenic zone, more than doubling in width from north to south and corresponding to a dramatic southward increase in forearc width (distance from the arc to the deformation front of the accretionary wedge). The minimum width of the seismogenic zone (distance between the intersections of the subduction interface with the 150°C and 350°C isotherms) increases from about 80 km, north of 16°N, to 230 km, at 13°N. The maximum width (between the 100°C and 450°C isotherms) ranges from about 150 km in the north to up to 320 km in the south. This large variation in the width of the seismogenic zone is a consequence of the increasing width of the accretionary wedge to the south, caused by the increased thickness of sediment on the subducting plate. There is good agreement between the thermally predicted seismogenic limits and the sparse distribution of recorded thrust earthquakes, which are observed only in the northern portion of the arc. Possible scenarios for mega-thrust earthquakes are discussed. Depending on the segment length (along-strike) of the rupture plane, the occurrence of an event of magnitude 8-9 cannot be excluded.
Bulletin Société Géologique de France

insu-00814056
https://hal-insu.archives-ouvertes.fr/insu-00814056
DOI : 10.2113/gssgfbull.184.1-2.47