Éditeur(s) : Florida State Museum, University of Florida Florida State Museum, University of Florida ( Gainsville, Fla. )
Résumé : (Bibliography) Includes bibliographical references.
Cover title.
Summaries in English and Spanish.
Bulletin of the Florida State Museum, volume 28, numbers 1-4
West Indies
Florida

Droits : Copyright held by the Florida Museum of Natural History, University of Florida. All rights reserved. Text, images and other media are for nonprofit, educational, and personal use of students, scholars, and the public. Any commercial use or republication by printed or electronic media is strictly prohibited without written permission of the museum. For permission or additional information, please contact the current editor of the Bulletin at bulletin@flmnh.ufl.edu.
09087148

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
BACKGROUND & AIMS: Nutrients influence non-alcoholic fatty liver disease. Essential fatty acids deficiency promotes various syndromes, including hepatic steatosis, through increased de novo lipogenesis. The mechanisms underlying such increased lipogenic response remain unidentified. METHODS: We used wild type mice and mice lacking Liver X Receptors to perform a nutrigenomic study that aimed at examining the role of these transcription factors. RESULTS: We showed that, in the absence of Liver X Receptors, essential fatty acids deficiency does not promote steatosis. Consistent with this, Liver X Receptors are required for the elevated expression of genes involved in lipogenesis in response to essential fatty acids deficiency. CONCLUSIONS: This work identifies, for the first time, the central role of Liver X Receptors in steatosis induced by essential fatty acids deficiency.
ISSN: 0168-8278

inserm-00872314
http://www.hal.inserm.fr/inserm-00872314
DOI : 10.1016/j.jhep.2013.01.006
PUBMED : 23333450

Éditeur(s) : HAL CCSD Frontiers
Résumé : International audience
Estrogens can induce rapid, short-lived physiological and behavioral responses, in addition to their slow, but long-term, effects at the transcriptional level. To be functionally relevant, these effects should be associated with rapid modulations of estrogens concentrations. 17β-estradiol is synthesized by the enzyme aromatase, using testosterone as a substrate, but can also be degraded into catechol-estrogens via hydroxylation by the same enzyme, leading to an increase or decrease in estrogens concentration, respectively. The first evidence that aromatase activity (AA) can be rapidly modulated came from experiments performed in Japanese quail hypothalamus homogenates. This rapid modulation is triggered by calcium-dependent phosphorylations and was confirmed in other tissues and species. The mechanisms controlling the phosphorylation status, the targeted amino acid residues and the reversibility seem to vary depending of the tissues and is discussed in this review. We currently do not know whether the phosphorylation of the same amino acid affects both aromatase and/or hydroxylase activities or whether these residues are different. These processes provide a new general mechanism by which local estrogen concentration can be rapidly altered in the brain and other tissues.
ISSN: 1662-4548

Droits : http://creativecommons.org/licenses/by/
hal-01142062
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01142062
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01142062/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01142062/file/fnins-09-00083.pdf
PUBMED : 25852459

Éditeur(s) : Société Française d'Ichtyologie
Résumé : In the present paper a new genus, Diretmoides, and a new species, Diretmoides parini, of the berycomorph family Diretmidae is described. The hitherto single genus of the family, Diretmus Johnson, 1863, therefore becomes monotypic while the new genus includes two species pauciradiatus (Woods, 1973) and parini sp. nov. The genus Diretmus is mainly charactcrized by three features (1) by its anus placed immediately anterior to the anal fin, (2) by a prepelvic ridge of ventral scutes and (3) by the high number of bony lamellae on the upper third of the operculum. The species of Diretmoides on the other hand have (1) their anus midway between the pelvics and the anal fin, (2) the ventral midline anterior to their pelvics is flat and is covered by normal body-scales and (3) there are only a few lamellae on the upper third of the operculum. Juveniles of the two Diretmoides-species differ from each other in their colour pattern,the adolescents and adults in meristic characters. All described species live meso-to bathypelagically. D. argenteus is widely distributed in tropical and temperate waters of all oceans. The two Diretmoides -species also live in the Atlantic as well as in the Pacific. However there is only one record of Diretmoides parini and none of D. pauciradiatus from the Indian Ocean. In addition to the described species, indication is given of the presumable existence of a third Diretmoides-species from off Japan. Artificial keys to adults and juveniJes are given at the end of this paper. NOT CONTROLLED OCR
Les auteurs décrivent un nouveau genre, Diretmoides, et une nouvelle espèce, Diretmoides parini. Le genre Diretmus ne comprend plus qu'une seule espèce D. argenteus Johnson, 1863; Diretmoides en comporte deux;D. pauciradiatus (Woods, 1973) d D. parini n.sp. Le genre Diretmus est caractérisé principalement par la position de l'anus juste en avant de l'anale par la présence en avant des pelviennes d'une carène épineuse ventrale et par la densité des lamelles osseuses sur le tiers supérieur de l'opercule. Chez Diretmoides l'anus est à mi-distance entre l'anale et les pelviennes; il n'y a pas de carène épineuse ventrale en avant des pelviennes et, sur le tiers supérieur de l'opercule, les lamelles osseuses sont peu nombreuses et éparses. Les jeunes Diretmoides se distinguent les uns des autres par leur coloration, les adolescents et les adultes par leurs caractères méristiques. Tous les Diretmidés actuellement connus sont des espèces méso à bathypélagiques. D. argenteus est largement distribué dans les eaux tropicales et tempérées de tous les océans. Les deux espèces de Diretmoides ont été signalées dans l'Atlantique et te Pacifique mais on ne connaît qu'une seule capture de D. parini dans l'océan indien et aucune de D. pauciradiatus. En outre. l'étude d'exemplaires provenant du Japon a amené les auteurs à souligner l'existence probable d'une troisième espèce de Diretmoides. Deux clés de détermination, l'une pour les adultes, l'autre pour les jeunes des trois espèces décrites, sont données à la fin de cette note. OCR NON CONTRÔLE
Cybium (Société Française d'Ichtyologie), 1981 , Vol. 5 , N. 1 , P. 33-60

Droits : 1981 Société Française d'Ichtyologie
http://archimer.ifremer.fr/doc/1981/publication-3746.pdf
http://archimer.ifremer.fr/doc/00000/3746/

Éditeur(s) : Société Française d'Ichtyologie
Résumé : On the basis of geographical distribution and morphological analysis of the Atlantic Howella , two subspecies of H. brodiei have been established, H. brodiei brodiei for the IndoPacific and H. brodiei atlanlica for the tropical and boreal Atlantic. H. sherborni has been recognized as a separate species, probably distributed circumglobally in southern Ocean but presently recorded only from the South Atlantic, the central South Pacific and from off southern and south-eastern Australia respectively. H. b. atlanlica and H. b. brodiei are distinct by having 3 scale rows between the lateral line and the origin of the second dorsal fin, while H. sherborni has 4 scale rows there. H. sherborni is in geographical contact with the two subspecies while H. b. brodiei and H. b. atlantica are geographically isolated from each other. The new subspecies, H. b. atlantica occurs in the North Atlantic and the tropical South Atlantic. Specimens from 75 mm SL and longer, predominantly occur in the boreal areas, while specimens less than that length occur in the tropical areas respectively. A day and night bathymetric distribution and a size-depth stratification have been observed. NOT CONTROLLED OCR
L'étude de la distribution et l'analyse des caractères méristiques des Howella de l'Atlantique montre la présence dans les régions tempérées nord et tropicales d'une sous-espèce nouvelle, H. brodiei atlantica, et dans la zone tempérée sud de H. sherborni. H. sherborni, caractérisé par 4 rangées d'écailles entre la ligne latérale et l'origine de la seconde dorsale, est au contact, dans l'Atlantique, de H. b. atlantica et, dans les Océans Indien et Pacifique de H. b. brodiei; ces deux sous-espèces, isolées géographiquement, possèdent 3 rangées d'écailles entre la ligne latérale et l'origine de la seconde dorsale. Les exemplaires d'H. b. atlanlica mesurant 75 mm LS ou plus ont été capturés dans la zone tempérée de l'Atlantique nord et ceux de moins de 75 mm principalement dans l'Atlantique tropical et subtropical nord. Les différences de distribution bathymétrique, le jour et la nuit et selon les tailles, sont étudiées chez H. b. atlanlica et H. sherborni. OCR NON CONTRÔLE
Cybium (Société Française d'Ichtyologie), 1991-02 , Vol. 15 , N. 2 , P. 111-128

Droits : 1991 Société Française d'Ichtyologie
http://archimer.ifremer.fr/doc/1991/publication-3769.pdf
http://archimer.ifremer.fr/doc/00000/3769/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Estrogens are known as steroid hormones affecting the brain in many different ways and a wealth of data now document effects on neurogenesis. Estrogens are provided by the periphery but can also be locally produced within the brain itself due to local aromatization of circulating androgens. Adult neurogenesis is described in all vertebrate species examined so far, but comparative investigations have brought to light differences between vertebrate groups. In teleost fishes, the neurogenic activity is spectacular and adult stem cells maintain their mitogenic activity in many proliferative areas within the brain. Fish are also quite unique because brain aromatase expression is limited to radial glia cells, the progenitor cells of adult fish brain. The zebrafish has emerged as an interesting vertebrate model to elucidate the cellular and molecular mechanisms of adult neurogenesis, and notably its modulation by steroids. The main objective of this review is to summarize data related to the functional link between estrogens production in the brain and neurogenesis in fish. First, we will demonstrate that the brain of zebrafish is an endogenous source of steroids and is directly targeted by local and/or peripheral steroids. Then, we will present data demonstrating the progenitor nature of radial glial cells in the brain of adult fish. Next, we will emphasize the role of estrogens in constitutive neurogenesis and its potential contribution to the regenerative neurogenesis. Finally, the negative impacts on neurogenesis of synthetic hormones used in contraceptive pills production and released in the aquatic environment will be discussed
ISSN: 0960-0760

hal-01174214
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01174214
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01174214/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01174214/file/Steroid%20modulation%20of%20neurogenesis.pdf
DOI : 10.1016/j.jsbmb.2015.06.011

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: The meiotic developmental pathway in yeast enables both differentiation of vegetative cells into haploid spores that ensure long-term survival, and recombination of the parental DNA to create genetic diversity. Despite the importance of proper metabolic regulation for the supply of building blocks and energy, little is known about the reprogramming of central metabolic pathways in meiotically differentiating cells during passage through successive developmental stages. Results: Metabolic regulation during meiotic differentiation in budding yeast was analyzed by integrating information on genome-wide transcriptional activity, 26 enzymatic activities in the central metabolism, the dynamics of 67 metabolites, and a metabolic flux analysis at mid-stage meiosis. Analyses of mutants arresting sporulation at defined stages demonstrated that metabolic reprogramming is tightly controlled by the progression through the developmental pathway. The correlation between transcript levels and enzymatic activities in the central metabolism varies significantly in a developmental stage-dependent manner. The complete loss of phosphofructokinase activity at mid-stage meiosis enables a unique setup of the glycolytic pathway which facilitates carbon flux repartitioning into synthesis of spore wall precursors during the co-assimilation of glycogen and acetate. The need for correct homeostasis of purine nucleotides during the meiotic differentiation was demonstrated by the sporulation defect of the AMP deaminase mutant amd1, which exhibited hyper-accumulation of ATP accompanied by depletion of guanosine nucleotides. Conclusions: Our systems-level analysis shows that reprogramming of the central metabolism during the meiotic differentiation is controlled at different hierarchical levels to meet the metabolic and energetic needs at successive developmental stages.
ISSN: 1471-2180

inserm-01094132
http://www.hal.inserm.fr/inserm-01094132
http://www.hal.inserm.fr/inserm-01094132/document
http://www.hal.inserm.fr/inserm-01094132/file/s12915-014-0060-x.pdf
DOI : 10.1186/s12915-014-0060-x

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: An environmental health inequality is a major public health concern in Europe. However just few studies take into account a large set of characteristics to analyze this problematic. The aim of this study was to identify and describe how socioeconomic, health accessibility and exposure factors accumulate and interact in small areas in a French urban context, to assess environmental health inequalities related to infant and neonatal mortality.Methods: Environmental indicators on deprivation index, proximity to high-traffic roads, green space, and healthcare accessibility were created using the Geographical Information System. Cases were collected from death certificates in the city hall of each municipality in the Nice metropolitan area. Using the parental addresses, cases were geocoded to their census block of residence. A classification using a Multiple Component Analysis following by a Hierarchical Clustering allow us to characterize the census blocks in terms of level of socioeconomic, environmental and accessibility to healthcare, which are very diverse definition by nature. Relation between infant and neonatal mortality rate and the three environmental patterns which categorize the census blocks after the classification was performed using a standard Poisson regression model for count data after checking the assumption of dispersion.Results: Based on geographic indicators, three environmental patterns were identified. We found environmental inequalities and social health inequalities in Nice metropolitan area. Moreover these inequalities are counterbalance by the close proximity of deprived census blocks to healthcare facilities related to mother and newborn. So therefore we demonstrate no environmental health inequalities related to infant and neonatal mortality.Conclusion: Examination of patterns of social, environmental and in relation with healthcare access is useful to identify census blocks with needs and their effects on health. Similar analyzes could be implemented and considered in other cities or related to other birth outcomes.
ISSN: 1476-069X

halshs-01366285
https://halshs.archives-ouvertes.fr/halshs-01366285
https://halshs.archives-ouvertes.fr/halshs-01366285/document
https://halshs.archives-ouvertes.fr/halshs-01366285/file/art_10.1186_s12940-016-0163-7.pdf
PUBMED : 27449640