Éditeur(s) : North-Holland Publishing Company, Amsterdam
Résumé : The Barents Sea is underlain by a thick (up to 5 km) sedimentary basin. Seismic refraction has outlined four main velocity discontinuities which have been correlated with geological units on the basis of the geological history of the region. The basin is underlain by a crystalline basement, the nature of which cannot be determined on the basis of seismic velocity alone. Metamorphosed Paleozoic units (velocities around 5-4 km/sec) lie over this basement. Their thickness is not well established but appears to reach 1 or 2 km in some cases. A very distinct and thick (up to 2.5 km) layer (4.1 km/sec) is found almost everywhere and is thought to correspond to a major discontinuity at the end ot the Paleozoic. This discontinuity is followed by a variable velocity layer (2.4-4 km/sec, up to 1.2 km thick) which includes Mesozoic and Cenozoic sediments and is limited to the south of the Barents Sea. The absence of thick Tertiary deposits support the idea that the Barents shelf was emergent at that time. Recent low-velocity sediments are found close to the shelf edge. [NOT CONTROLLED OCR]
Earth and Planetary Science Letters (North-Holland Publishing Company, Amsterdam), 1974 , Vol. 24 , P. 33-47

Droits : North-Holland Publishing Company, Amsterdam
http://archimer.ifremer.fr/doc/1974/publication-5447.pdf
http://archimer.ifremer.fr/doc/00000/5447/

Éditeur(s) : Bruxelles : Société des Beaux-Arts
Siècle(s) traité(s) : 19
Droits : Domaine public
Provenance : Archives territoriales de Guyane
Permalien : http://www.manioc.org/patrimon/GAD11061
GAD11061

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The Hedgehog (Hh) family of secreted proteins act as morphogens to control embryonic patterning and development in a variety of organ systems. Post-translational covalent attachment of cholesterol and palmitate to Hh proteins are critical for multimerization and long range signaling potency. However, the biological impact of lipid modifications on Hh ligand distribution and signal reception in humans remains unclear. In the present study, we report a unique case of autosomal recessive syndromic 46,XY Disorder of Sex Development (DSD) with testicular dysgenesis and chondrodysplasia resulting from a homozygous G287V missense mutation in the hedgehog acyl-transferase (HHAT) gene. This mutation occurred in the conserved membrane bound O-acyltransferase (MBOAT) domain and experimentally disrupted the ability of HHAT to palmitoylate Hh proteins such as DHH and SHH. Consistent with the patient phenotype, HHAT was found to be expressed in the somatic cells of both XX and XY gonads at the time of sex determination, and Hhat loss of function in mice recapitulates most of the testicular, skeletal, neuronal and growth defects observed in humans. In the developing testis, HHAT is not required for Sertoli cell commitment but plays a role in proper testis cord formation and the differentiation of fetal Leydig cells. Altogether, these results shed new light on the mechanisms of action of Hh proteins. Furthermore, they provide the first clinical evidence of the essential role played by lipid modification of Hh proteins in human testicular organogenesis and embryonic development.
ISSN: 1553-7390

hal-01063929
https://hal.archives-ouvertes.fr/hal-01063929
DOI : 10.1371/journal.pgen.1004340
PUBMED : 24784881

Éditeur(s) : Amsterdam : G. et I. Blaeu, 1635 Amsterdam : G. et I. Blaeu, 1635
Résumé : Detached from and originally published in the French ed. of W.J. Blaeu's atlas: Le theatre du monde ou Novvel atlas, 1635. Shows southeast coast of North America from Virginia to north coast of South America to east of Trinidad, west coast of Central America, West Indies. Includes embellished title cartouche, coats-of-arms. ill. scale and ill. of ships at sea. Includes scales in milliaria germanica and milliaria hispanica. Text in French on verso: Les isles de Amerique en l'ocean septentrional, audevant du Golfe de Mexique, & quelques provinces du continent. Engraved. Hand colored. Has vertical fold line at center of sheet. Relief represented by hachures. UCF Libraries' copy has reinforcement on right edge. This item is part of the West Indies collection.
(Language) Title in Latin: place names primarily in Spanish and Latin ; text on verso in French.
Caribbean area
North America
South America
Caribbean area
West Indies
West Indies

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
G4390 1635.B

Éditeur(s) : Paris : Librairie commerciale

Droits : Domaine public
Provenance : Université de Nantes. Service commun de la documentation
Permalien : http://www.manioc.org/patrimon/NAN13059-2
NAN13059-2

Éditeur(s) : M. Nijhoff. M. Nijhoff. ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1.-39. jaarg.; 1919/20-1959.
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 volumes.
(Issuing Body) Pub. in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Editors: 1919/20- Janus Boeke and others.
Suriname
Netherlands Antilles
Suriname
Netherlands Antilles

ABV7932
01646507
000328385
23014833
0372-7289

Éditeur(s) : M. Nijhoff. M. Nijhoff. ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1.-39. jaarg.; 1919/20-1959.
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 volumes.
(Issuing Body) Pub. in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Editors: 1919/20- Janus Boeke and others.
Suriname
Netherlands Antilles
Suriname
Netherlands Antilles

ABV7932
01646507
000328385
23014833
0372-7289

Éditeur(s) : F. L'Honore F. L'Honore ( Amsterdam )
Haiti
Haiti

000907785
AEL6949
02017360

Éditeur(s) : [s.n.] (Amsterdam)
Résumé : Appartient à l’ensemble documentaire : FranceAm
Bibliothèque nationale de France, département Philosophie, histoire, sciences de l'homme, G-28074

Droits : domaine public
http://gallica.bnf.fr/ark:/12148/bpt6k109690m

Éditeur(s) : HAL CCSD European Respiratory Society
Résumé : IF 8.332
International audience
The respiratory manifestations of eosinophilic granulomatosis with polyangiitis (EGPA) have not been studied in detail. In this retrospective multicentre study, EGPA was defined by asthma, eosinophilia and at least one new onset extra-bronchopulmonary organ manifestation of disease. The study population included 157 patients (mean±SD age 49.4±14.1 years), with a mean±SD blood eosinophil count of 7.4±6.4×109 L-1 at diagnosis. There was a mean±SD of 11.8±18.2 years from the onset of asthma to the diagnosis of EGPA, of 1.4±8.4 years from the first onset of peripheral eosinophilia to the diagnosis of EGPA, and of 7.4±6.4 years from EGPA diagnosis to the final visit. Despite inhaled and oral corticosteroid treatment, the severity of asthma increased 3-6 months before the onset of the systemic manifestations. Asthma was severe in 57%, 48%, and 56% of patients at diagnosis, at 3 years, and at the final visit, respectively. Persistent airflow obstruction was present in 38%, 30%, and 46% at diagnosis, at 3 years, and at the final visit, respectively. In EGPA, asthma is severe, antedates systemic manifestations by a mean of 12 years, and progresses to long-term persistent airflow obstruction despite corticosteroids in a large proportion of patients, which affects long-term management and morbidity. Copyright © 2016 ERS.
ISSN: 0903-1936

hal-01406073
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01406073
DOI : 10.1183/13993003.00097-2016
PUBMED : 27587545

Éditeur(s) : D.J. Changuion D.J. Changuion ( Amsterdam )
Résumé : (Statement of Responsibility) Par M. Bossu ...
The author's observations during his first two visits to the country, 1751-1757 and 1757-1762.
Frontispiece and plates bound between vols. l and 2.
W. Howes, U.S. -iana, 1962, no. B626 (p. 66)
Mississippi River Valley
Southern States
Louisiana
Haiti

001853108
02509582
AJS7468
gs 18000186 //r19

Éditeur(s) : [s.n.] (Amsterdam)
Résumé : Appartient à l’ensemble documentaire : FranceAm
Bibliothèque nationale de France, département Philosophie, histoire, sciences de l'homme, G-28072

Droits : domaine public
http://gallica.bnf.fr/ark:/12148/bpt6k1096889

Éditeur(s) : M. Nijhoff M. Nijhoff ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1 jaarg. (1919/20)-39 jaarg. (Dec. 1959).
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 vols.
(Issuing Body) Published in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Suriname
Netherland Antilles

000328385
27645363
ABV7932
sn 93026062

Éditeur(s) : M. Nijhoff. M. Nijhoff. ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1.-39. jaarg.; 1919/20-1959.
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 volumes.
(Issuing Body) Pub. in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Editors: 1919/20- Janus Boeke and others.
Suriname
Netherlands Antilles
Suriname
Netherlands Antilles

ABV7932
01646507
000328385
23014833
0372-7289

Éditeur(s) : M. Nijhoff. M. Nijhoff. ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1.-39. jaarg.; 1919/20-1959.
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 volumes.
(Issuing Body) Pub. in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Editors: 1919/20- Janus Boeke and others.
Suriname
Netherlands Antilles
Suriname
Netherlands Antilles

ABV7932
01646507
000328385
23014833
0372-7289

Éditeur(s) : M. Nijhoff. M. Nijhoff. ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1.-39. jaarg.; 1919/20-1959.
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 volumes.
(Issuing Body) Pub. in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Editors: 1919/20- Janus Boeke and others.
Suriname
Netherlands Antilles
Suriname
Netherlands Antilles

ABV7932
01646507
000328385
23014833
0372-7289

Éditeur(s) : Wed. I. Ottens (Amsterdam)
Résumé : Échelle(s) : Milliaria Germanica... 15 [=Om. 116 ; 1:957 850 ]
Appartient à l’ensemble documentaire : AnvilAmN
Bibliothèque nationale de France, département Cartes et plans, CPL GE DD-2987 (9085 B)
Amérique (parties)
Martinique (France)

Droits : domaine public
http://gallica.bnf.fr/ark:/12148/btv1b5902450j

Éditeur(s) : M. Nijhoff. M. Nijhoff. ( 's-Gravenhage )
Résumé : (Dates or Sequential Designation) 1.-39. jaarg.; 1919/20-1959.
(Numbering Peculiarities) Aug. 1944-Nov. 1945 nos. were not issued.
(Numbering Peculiarities) "1. jaargang" is in 2 volumes.
(Issuing Body) Pub. in Amsterdam by N. v. Boek- en Handelsdrukkerij, 1919-20.
Editors: 1919/20- Janus Boeke and others.
Suriname
Netherlands Antilles
Suriname
Netherlands Antilles

ABV7932
01646507
000328385
23014833
0372-7289

Éditeur(s) : [s.n.] (Amsterdam)
Résumé : Appartient à l’ensemble documentaire : FranceAm
Bibliothèque nationale de France, département Philosophie, histoire, sciences de l'homme, G-28071

Droits : domaine public
http://gallica.bnf.fr/ark:/12148/bpt6k109687x

Éditeur(s) : Paris : Arthus Bertrand
Siècle(s) traité(s) : 19
Droits : Domaine public
Provenance : Collectivité territoriale de Martinique. Bibliothèque Schoelcher
Permalien : http://www.manioc.org/patrimon/SCH13079
SCH13079