Éditeur(s) : Gauthier-Villars
Oceanologica Acta (0399-1784) (Gauthier-Villars), 1989-04 , Vol. 12 , N. 2 , P. 131-140

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00131/24224/22217.pdf
http://archimer.ifremer.fr/doc/00131/24224/

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Pituitary adenomas are currently classified by histological, immunocytochemical and numerous ultrastructural characteristics lacking unequivocal prognostic correlations. We investigated the prognostic value of a new clinicopathological classification with grades based on invasion and proliferation. This retrospective multicentric case-control study comprised 410 patients who had surgery for a pituitary tumour with long-term follow-up. Using pituitary magnetic resonance imaging for diagnosis of cavernous or sphenoid sinus invasion, immunocytochemistry, markers of the cell cycle (Ki-67, mitoses) and p53, tumours were classified according to size (micro, macro and giant), type (PRL, GH, FSH/LH, ACTH and TSH) and grade (grade 1a: non-invasive, 1b: non-invasive and proliferative, 2a: invasive, 2b: invasive and proliferative, and 3: metastatic). The association between patient status at 8-year follow-up and age, sex, and classification was evaluated by two multivariate analyses assessing disease- or recurrence/progression-free status. At 8 years after surgery, 195 patients were disease-free (controls) and 215 patients were not (cases). In 125 of the cases the tumours had recurred or progressed. Analyses of disease-free and recurrence/progression-free status revealed the significant prognostic value (p < 0.001; p < 0.05) of age, tumour type, and grade across all tumour types and for each tumour type. Invasive and proliferative tumours (grade 2b) had a poor prognosis with an increased probability of tumour persistence or progression of 25- or 12-fold, respectively, as compared to non-invasive tumours (grade 1a). This new, easy to use clinicopathological classification of pituitary endocrine tumours has demonstrated its prognostic worth by strongly predicting the probability of post-operative complete remission or tumour progression and so could help clinicians choose the best post-operative therapy.
ISSN: 0001-6322

hal-00875723
https://hal.archives-ouvertes.fr/hal-00875723
DOI : 10.1007/s00401-013-1084-y
PUBMED : 23400299

Éditeur(s) : Gauthier-Villars
Résumé : The littoral area of Benin is a lagoonal-estuarial, indeed even deltaic, environment. Poor in species, the mangrove of Benin belongs to the tropical Atlantic type tending to be humid, considering the "drought belt" which affects this region. It undergoes profound hydrological changes in the course of the different seasons in relation to the Mono and Couffo Rivers. The granulometric analysis and the study of the facies makes clear a lenticular-type sedimentation in relation to numerous and rapid hydrodynamic variations. The clayish quartzose sediment also contains a chemical phase (pyrite is transformed through oxidation into jarosite, gypsum and halite in relation to the micromilieux of evaporation) and an important organic phase - with a pH level ranging from 5 to 6. Kaolinite, from the nearby "Continental terminal", is deposited during calm periods. The smectites seem linked to high energy, sandier deposits and their origin should probably be sought in a far away back country (Eocene, basement).
Oceanologica Acta, Special issue (0399-1784) (Gauthier-Villars), 1982

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00246/35730/34238.pdf
http://archimer.ifremer.fr/doc/00246/35730/

Éditeur(s) : Amer Meteorological Soc
Résumé : Salinity measurements from 119 surface drifters in 2007-12 were assessed; 80% [Surface Velocity Program with a barometer with a salinity sensor (SVP-BS)] and 75% [SVP with salinity (SVP-S)] of the salinity data were found to be usable, after editing out some spikes. Sudden salinity jumps are found in drifter salinity records that are not always associated with temperature jumps, in particular in the wet tropics. A method is proposed to decide whether and how to correct those jumps, and the uncertainty in the correction applied. Northeast of South America, in a region influenced by the Amazon plume and fresh coastal water, drifter salinity is very variable, but a comparison with data from the Soil Moisture and Ocean Salinity satellite suggests that this variability is usually reasonable. The drifter salinity accuracy is then explored based on comparisons with data from Argo floats and from thermosalinographs (TSGs) of ships of opportunity. SVP-S/SVP-BS drifter records do not usually present significant biases within the first 6 months, but afterward biases sometimes need to be corrected (altogether, 16% of the SVP-BS records). Biases start earlier after 3 months for drifters not protected by antifouling paint. For the few drifters for which large corrections were applied to portions of the record, the accuracy cannot be proven to be better than 0.1 psu, and it cannot be proven to be better than 0.5 psu for data in the largest variability area off northeast South America. Elsewhere, after excluding portions of the records with suspicious salinity jumps or when large corrections were applied, the comparisons rule out average biases in individual drifter salinity record larger than 0.02 psu (midlatitudes) and 0.05 psu (tropics).
Journal Of Atmospheric And Oceanic Technology (0739-0572) (Amer Meteorological Soc), 2014-04 , Vol. 31 , N. 4 , P. 967-983

Droits : 2014 American Meteorological Society
http://archimer.ifremer.fr/doc/00190/30095/28748.pdf
DOI:10.1175/JTECH-D-13-00158.1
http://archimer.ifremer.fr/doc/00190/30095/