Éditeur(s) : HAL CCSD Springer Verlag
Résumé : GPS velocities and seismicity across the Betic-Rif Arc structural domains (Morocco and Iberia) provide a basis to evaluate present-day seismotectonic processes between different deformation belts. The results show asymmetric movements in the complex Alboran system accommodating the convergence between the African (Nubian) and Eurasian plates. While the Betic Mountains are attached to Iberia, moving toward the southeast with respect to Africa, the Rif is divided into three blocks with distinct displacements relative to Nubia: (1) the Tangier block moving southeastward, (2) the Central Rif block moving SSW, and (3) the Oriental Rif block undergoing clockwise rotation. GPS-derived motions decrease in rate from the Rif nappes complex to the foreland.
ISSN: 0010-7999

hal-00411144
https://hal.archives-ouvertes.fr/hal-00411144
DOI : 10.1016/j.crte.2008.02.003

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
We use velocities from 65 continuous stations and 31 survey-mode GPS sites as well as kinematic modeling to investigate present day deformation along the Africa-Iberia plate boundary zone in the western Mediterranean region. The GPS velocity field shows southwestward motion of the central part of the Rif Mountains in northern Morocco with respect to Africa varying between 3.5 and 4.0 mm/yr, consistent with prior published results. Stations in the southwestern part of the Betic Mountains of southern Spain move west-southwest with respect to Eurasia (similar to 2-3 mm/yr). The western component of Betics motion is consistent with partial transfer of Nubia-Eurasia plate motion into the southern Betics. The southward component of Betics motion with respect to Iberia is kinematically consistent with south to southwest motion of the Rif Mountains with respect to Africa. We use block modeling, constrained by mapped surface faults and seismicity to estimate the geometry and rates of strain accumulation on plate boundary structures. Our preferred plate boundary geometry includes one block between Iberia and Africa including the SW Betics, Alboran Sea, and central Rif. This geometry provides a good fit to the observed motions, suggesting a wide transpressive boundary in the westernmost Mediterranean, with deformation mainly accommodated by the Gloria-Azores fault system to the West and the Rif-Tell lineament to the East. Block boundaries encompass aspects of earlier interpretations suggesting three main deformation styles: (i) extension along the NE-SW trending Trans-Alboran shear zone, (ii) dextral strike-slip in the Betics corresponding to a well defined E-W seismic lineament, and (iii) right lateral strike-slip motion extending West to the Azores and right-lateral motion with compression extending East along the Algerian Tell. We interpret differential motion in the Rif-Alboran-Betic system to be driven both by surface processes related the Africa-Eurasia oblique convergence and sub-crustal dynamic processes associated with the long history of subduction of the Neotethys ocean lithosphere. The dextral slip identified in the Betic Mountains in Southern Spain may be related to the offshore fault that produced the Great 1755 Lisbon Earthquake, and as such may represent a significant seismic hazard for the West Mediterranean region.
ISSN: 0012-821X

hal-00618337
https://hal.archives-ouvertes.fr/hal-00618337
DOI : 10.1016/j.epsl.2011.05.048

Éditeur(s) : HAL CCSD American Chemical Society
Résumé : International audience
Four bicyclic and three pentacyclic guanidine alkaloids (1–7) were isolated from a French Polynesian Monanchora n. sp. sponge, along with the known alkaloids monalidine A (8), enantiomers 9–11 of known natural product crambescins, and the known crambescidins 12–15. Structures were assigned by spectroscopic data interpretation. The relative and absolute configurations of the alkaloids were established by analysis of 1H NMR and NOESY spectra and by circular dichroism analysis. The new norcrambescidic acid (7) corresponds to interesting biosynthetic variation within the pentacyclic core. All compounds exhibited antiproliferative and cytotoxic efficacy against KB, HCT116, HL60, MRC5, and B16F10 cancer cells, with IC50 values ranging from 4 nM to 10 μM.
ISSN: 0163-3864

hal-01584556
https://hal.archives-ouvertes.fr/hal-01584556
DOI : 10.1021/acs.jnatprod.6b00168