Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
Walter W. S. Cook standing in Nicholls Town, a town in northeastern Andros, Bahamas. Cook was the founding director of the Institute of Fine Arts at New York University, served as an art professor from 1932 to 1953, and was historian of Medieval Spanish art. He was a companion of William Junior Bryant during Bryant’s trips to Andros and New Providence in 1946. In the distance of the image is a British flag, plantain or banana trees, and people walking down a narrow dirt path. Slide labeled Nicolls Town Andros Mar. '46.
Bahamas -- North America -- Nicholls Town, Andros

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 6:9
http://ufdc.ufl.edu/AA00028493/00001

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
Although TRAIL (tumor necrosis factor (TNF)-related apoptosis inducing ligand) is a well-known apoptosis inducer, we have previously demonstrated that acidic extracellular pH (pHe) switches TRAIL-induced apoptosis to regulated necrosis (or necroptosis) in human HT29 colon and HepG2 liver cancer cells. Here, we investigated the role of RIPK1 (receptor interacting protein kinase 1), RIPK3 and PARP-1 (poly (ADP-ribose) polymerase-1) in TRAIL-induced necroptosis in vitro and in concanavalin A (Con A)-induced murine hepatitis. Pretreatment of HT29 or HepG2 with pharmacological inhibitors of RIPK1 or PARP-1 (Nec-1 or PJ-34, respectively), or transient transfection with siRNAs against RIPK1 or RIPK3, inhibited both TRAIL-induced necroptosis and PARP-1-dependent intracellular ATP depletion demonstrating that RIPK1 and RIPK3 were involved upstream of PARP-1 activation and ATP depletion. In the mouse model of Con A-induced hepatitis, where death of mouse hepatocytes is dependent on TRAIL and NKT (Natural Killer T) cells, PARP-1 activity was positively correlated with liver injury and hepatitis was prevented both by Nec-1 or PJ-34. These data provide new insights into TRAIL-induced necroptosis with PARP-1 being active effector downstream of RIPK1/RIPK3 initiators and suggest that pharmacological inhibitors of RIPKs and PARP-1 could be new treatment options for immune-mediated hepatitis.
ISSN: 1350-9047

inserm-00871432
http://www.hal.inserm.fr/inserm-00871432
DOI : 10.1038/cdd.2012.90
PUBMED : 22814620

Éditeur(s) : [s.n.] ( Washington )
Résumé : Complete in 8 sheets.
"Polyconic projection."
Military grid.
"Contour interval 25, 50 feet changing to 100 feet at 100 foot contour."
Six classes of roads or trails are shown.
Provisional edition, 1940, by U.S. Army, Corps of Engineers, has title "Trinidad and Tobago .. Tactical map."
Marginal map: Index to sheets.
Trinidad and Tobago
Trinidad
Trinidad

Droits : This item is a work of the U.S. federal government and not protected by copyright pursuant to 17 U.S.C. §105.
002631426
06455957
AMZ8170
http://ufdc.ufl.edu/UF00065429/00001

Éditeur(s) : HAL CCSD
Résumé : Scope: TNF-Related Apoptosis-Inducing Ligand (TRAIL) induces apoptosis via the extrinsic death pathway in human colon cancer cells. Short Chain Fatty Acids (SCFA) by contrast induce apoptosis of cancer cells via the intrinsic death pathway. We have previously shown that food-grade dairy propionibacteria induce intrinsic apoptosis of colon cancer cells, via SCFA metabolites (propionate and acetate) acting on mitochondria. We investigate here the possible synergistic pro-apoptotic effect between Propionibacterium freudenreichii and TRAIL. Methods and results: Whole transcriptomic analysis demonstrated that propionibacterial supernatant or propionibacterial SCFA, in combination with TRAIL, increased pro-apoptotic gene expression (TRAIL-R2/DR5) and decreased anti-apoptotic gene expression (FLIPL, XIAP) in HT29 human colon cancer cells. The revealed synergistic pro-apoptotic effect, depending on both death receptors (TRAIL-R1/DR4, TRAIL-R2/DR5) and caspases (caspase-8, -9 and -3) activation, was lethal on cancer cells but not on normal human intestinal epithelial cells (HIEC), and was inhibited by Bcl-2 expression. Finally, milk fermented by P. freudenreichii induced HT29 cells apoptosis and enhanced TRAIL cytotoxic activity, as did P. freudenreichii culture supernatants or its SCFA metabolites.Conclusion: The revealed synergy opens new applications for food-grade P. freudenreichii-containing products as new adjuvants to potentiate TRAIL-based cancer therapy in colorectal cancer.
International Scientific Conference on Probiotics and Prebiotics - IPC2016
Budapest, Hungary

hal-01286497
https://hal.archives-ouvertes.fr/hal-01286497
PRODINRA : 349367

Éditeur(s) : Army Map Service, U.S. Army, Army Map Service, U.S. Army Army Map Service, U.S. Army, Army Map Service, U.S. Army ( Washington, D.C )
Résumé : (Internal Comments) prepared under the direction of the Chief of Engineers, U.S. Army, by the Army Map Service.
(Statement of Responsibility) prepared under the direction of the Chief of Engineers, U.S. Army, by the Army Map Service.
Relief shown by contours and spot heights.
Complete in 8 sheets.
Military grid.
"Contour interval 25, 50 feet changing to 100 feet at 100 foot contour."
Six classes of roads or trails are shown.
Provisional edition, 1940, by U.S. Army, Corps of Engineers, has title "Trinidad and Tobago .. Tactical map."
Marginal map: Index to sheets.
Trinidad and Tobago -- Trinidad
Trinidad

06455957

Résumé : Complete in 9 sheets.
"Polyconic."
Military grid.
Relief shown by hachures with spot heights in feet.
Four classes of roads or trails are shown.
Marginal map: Index to adjoining sheets.
Jamaica
Jamaica

Droits : This item is a work of the U.S. federal government and not protected by copyright pursuant to 17 U.S.C. §105.
002630415
AMZ7150
06455596
6455596
http://ufdc.ufl.edu/UF00080728/00001

Éditeur(s) : HAL CCSD Impact journals
Résumé : International audience
TNF-Related Apoptosis-Inducing Ligand (TRAIL) is a well-known apoptosis inducer, which activates the extrinsic death pathway. TRAIL is pro-apoptotic on colon cancer cells, while not cytotoxic towards normal healthy cells. However, its clinical use is limited by cell resistance to cell death which occurs in approximately 50% of cancer cells. Short Chain Fatty Acids (SCFA) are also known to specifically induce apoptosis of cancer cells. In accordance, we have shown that food grade dairy propionibacteria induce intrinsic apoptosis of colon cancer cells, via the production and release of SCFA (propionate and acetate) acting on mitochondria. Here, we investigated possible synergistic effect between Propionibacterium freudenreichii and TRAIL. Indeed, we hypothesized that acting on both extrinsic and intrinsic death pathways may exert a synergistic pro-apoptotic effect. Whole transcriptomic analysis demonstrated that propionibacterial supernatant or propionibacterial metabolites (propionate and acetate), in combination with TRAIL, increased pro-apoptotic gene expression (TRAIL-R2/DR5) and decreased anti-apoptotic gene expression (FLIP, XIAP) in HT29 human colon cancer cells. The revealed synergistic pro-apoptotic effect, depending on both death receptors (TRAIL-R1/DR4, TRAIL-R2/DR5) and caspases (caspase-8, -9 and -3) activation, was lethal on cancer cells but not on normal human intestinal epithelial cells (HIEC), and was inhibited by Bcl-2 expression. Finally, milk fermented by P. freudenreichii induced HT29 cells apoptosis and enhanced TRAIL cytotoxic activity, as did P. freudenreichii DMEM culture supernatants or its SCFA metabolites. These results open new perspectives for food grade P. freudenreichii-containing products in order to potentiate TRAIL-based cancer therapy in colorectal cancer
ISSN: 1949-2553

hal-01259215
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01259215
DOI : 10.18632/oncotarget.6881
PUBMED : 26771233

Éditeur(s) : HAL CCSD Impact journals
Résumé : International audience
TNF-Related Apoptosis-Inducing Ligand (TRAIL) is a well-known apoptosis inducer, which activates the extrinsic death pathway. TRAIL is pro-apoptotic on colon cancer cells, while not cytotoxic towards normal healthy cells. However, its clinical use is limited by cell resistance to cell death which occurs in approximately 50% of cancer cells. Short Chain Fatty Acids (SCFA) are also known to specifically induce apoptosis of cancer cells. In accordance, we have shown that food grade dairy propionibacteria induce intrinsic apoptosis of colon cancer cells, via the production and release of SCFA (propionate and acetate) acting on mitochondria. Here, we investigated possible synergistic effect between Propionibacterium freudenreichii and TRAIL. Indeed, we hypothesized that acting on both extrinsic and intrinsic death pathways may exert a synergistic pro-apoptotic effect. Whole transcriptomic analysis demonstrated that propionibacterial supernatant or propionibacterial metabolites (propionate and acetate), in combination with TRAIL, increased pro-apoptotic gene expression (TRAIL-R2/DR5) and decreased anti-apoptotic gene expression (FLIP, XIAP) in HT29 human colon cancer cells. The revealed synergistic pro-apoptotic effect, depending on both death receptors (TRAIL-R1/DR4, TRAIL-R2/DR5) and caspases (caspase-8,-9 and-3) activation, was lethal on cancer cells but not on normal human intestinal epithelial cells (HIEC), and was inhibited by Bcl-2 expression. Finally, milk fermented by P. freudenreichii induced HT29 cells apoptosis and enhanced TRAIL cytotoxic activity, as did P. freudenreichii DMEM culture supernatants or its SCFA metabolites. These results open new perspectives for food grade P. freudenreichii-containing products in order to potentiate TRAIL-based cancer therapy in colorectal cancer.
ISSN: 1949-2553

hal-01404971
https://hal.inria.fr/hal-01404971
https://hal.inria.fr/hal-01404971/document
https://hal.inria.fr/hal-01404971/file/2016%20Oncotarget_The%20probiotic%20Propionibacterium%20freudenreichii%20as%20a%20new%20adjuvant%20for%20TRAIL-based%20therapy%20in%20colorectal%20cancer..pdf
DOI : 10.18632/oncotarget.6881

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
A man and a woman walk along a sandy path near Winding Bay, Great Abaco. The woman, pictured, traveled with William Junior Bryant during his trip to the Bahamas in April 1965. In the distance is a thatch roofed house. Slide labeled Hot on Winding Bay Where Canadian Lived 3 Mos. April '65.
Bahamas -- North America -- Winding Bay, Great Abaco

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 11:4
http://ufdc.ufl.edu/AA00028951/00001

Éditeur(s) : [s.n.] ( Washington )
Résumé : Complete in 8 sheets.
"Polyconic projection."
Military grid.
"Contour interval 25, 50 feet changing to 100 feet at 100 foot contour."
Six classes of roads or trails are shown.
Provisional edition, 1940, by U.S. Army, Corps of Engineers, has title "Trinidad and Tobago .. Tactical map."
Marginal map: Index to sheets.
Trinidad and Tobago
Trinidad
Trinidad

002631426
06455957
AMZ8170
http://ufdc.ufl.edu/UF00065429/00002

Éditeur(s) : [s.n.] ( Washington )
Résumé : "Polyconic projection."
Military grid.
Relief shown by hachures with spot heights in feet.
Five classes of roads or trails are shown.
Marginal map: Index to adjoining sheets.
Guyana
Guyana

Droits : This item is a work of the U.S. federal government and not protected by copyright pursuant to 17 U.S.C. §105.
06453929
002632176
http://ufdc.ufl.edu/UF00082555/00001

Résumé : Herbácea perenne, con ramas rastreras o ascendentes, con raíces en los nudos. Hojas opuestas, sésiles, elípticas a obovadas de 2 a 12 cm, obtusas a agudas en el ápice, más o menos cuneadas en la base, serrado-dentadas, a menudo lobuladas. Cabezuelas solitarias en pedúnculos axilares o terminales; involucros campanulados; capítulos radiados, amarillos, en número de 10 aproximadamente. Aquenio obovoide, tuberculado.
Herbacée pérenne, à branches rampantes ou ascendantes, avec des racines au niveau des noeuds. Feuilles opposées, sessiles, elliptiques à obovées de 2 à 12 cm, obtuses à aiguës à la pointe, plus ou moins cunéiformes à la base, aux bords découpés en dents-de-scie, souvent lobées. Capitules solitaires en pédoncules axillaires ou terminaux; involucrés en forme de clochette; capitules radiés, jaunes, approximativement au nombre de 10. Akène ovoïde, tuberculé.
Perennial herb, with trailing or ascending branches rooting at thenodes.  Leaves opposite, sessile, elliptical to obovate, 2-12 cm x 1-6 cm, apex acute,cuneate at the base, marginsserrate-dentate often lobed; inflorescence a capitulum on axillary or terminal peduncles; ray florets bright yellow; achenes 5mm long, oblong to obovoid, compressed.
Originaria de América, ampliamente distribuida en las regiones tropicales y subtropicales del mundo.
Originaire d’;Amérique, largement répandue dans les régions tropicales et subtropicales du monde.
Native to America, widely distributed in trop

http://www.tramil.net/fototeca/plant360

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
A man walks along a sandy path near Winding Bay, Great Abaco, Bahamas. The man wears a blue plaid shirt and a straw hat. The path is surrounded by tall grasses and bushes. Slide labeled Farm Near Winding Bay N of Cherokee April '65.
Bahamas -- North America -- Winding Bay, Great Abaco

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 10:20
http://ufdc.ufl.edu/AA00028947/00001

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
A sandy path surrounded by beach plants, which leads to the sea near Winding Bay, Great Abaco, Bahamas. Slide labeled Winding Bay April '65.
Bahamas -- North America -- Winding Bay, Great Abaco

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 11:1
http://ufdc.ufl.edu/AA00028948/00001

Éditeur(s) : HAL CCSD Wiley-Blackwell
Résumé : International audience
UNLABELLED: Interleukin (IL)-33, a member of the IL-1 cytokine family, positively correlates with acute hepatitis and chronic liver failure in mice and humans. IL-33 is expressed in hepatocytes and is regulated by natural killer T (NKT) cells during concanavalin A (ConA)-induced acute liver injury. Here, we investigated the molecular mechanisms underlying the expression of IL-33 during acute hepatitis. The expression of IL-33 and its regulation by death receptor pathways was investigated after the induction of ConA-acute hepatitis in wildtype (WT), perforin(-/-) , tumor necrosis factor related apoptosis inducing ligand (TRAIL)(-/-) , and NKT cell-deficient (CD1d(-/-) ) mice. In addition, we used a model of acute liver injury by administering Jo2/Fas-antibody or D-galactosamine-tumor necrosis factor alpha (TNFα) in WT mice. Finally, the effect of TRAIL on IL-33 expression was assessed in primary cultured murine hepatocytes. We show that IL-33 expression in hepatocytes is partially controlled by perforin during acute liver injury, but not by TNFα or Fas ligand (FasL). Interestingly, the expression of IL-33 in hepatocytes is blocked during ConA-acute hepatitis in TRAIL-deficient mice compared to WT mice. In contrast, administration of recombinant murine TRAIL associated with ConA-priming in CD1d-deficient mice or in vitro stimulation of murine hepatocytes by TRAIL but not by TNFα or Jo2 induced IL-33 expression in hepatocytes. The IL-33-deficient mice exhibited more severe ConA liver injury than WT controls, suggesting a protective effect of IL-33 in ConA-hepatitis. CONCLUSION: The expression of IL-33 during acute hepatitis is dependent on TRAIL, but not on FasL or TNFα.
ISSN: 0270-9139

hal-00874194
https://hal.archives-ouvertes.fr/hal-00874194
PUBMED : 22961755
DOI : 10.1002/hep.25893

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
Sandy path lined with trees on Great Guana Cay, Abaco, Bahamas. Great Guana Cay is one of the several cays and islands in the Bahamas that form a 120-mile-long chain stretching over 650 square miles. Slide labeled Path to Beach Great Guiana Feb '57.
Bahamas -- North America -- Great Guana Cay, Abaco

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 10:2
http://ufdc.ufl.edu/AA00028928/00001

Éditeur(s) : HAL CCSD Thieme Publishing
Résumé : International audience
The purpose of this study was to investigate thermal response, hydration and performance over a 6-day, 142-km trail running race in tropical conditions. 9 participants competed in the 2011 Gwadarun (30 °C ± 2.4 °C and 82 ± 4 % RH). Data were collected on days 1, 4 and 6. Gastrointestinal temperature (T gi ) and heart rate (HR) were measured using portable telemetry units, whereas blood samples were collected for hematocrit, osmolarity, plasma concentrations, alkaline reserves and creatine phosphokinase. The performances expressed in speed were correlated with both total body water and body mass
ISSN: 0172-4622

hal-01135194
https://hal.univ-antilles.fr/hal-01135194
https://hal.univ-antilles.fr/hal-01135194/document
https://hal.univ-antilles.fr/hal-01135194/file/s-0033-1361186-ThermoregulationHydratationPerformance.pdf
DOI : 10.1055/s-0033-1361186

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
A man walks along a sandy path flanked by trees located near Nicholls Town, a town in northeastern Andros, Bahamas. The man pictured was a companion of William Junior Bryant and Walter W. S. Cook during Bryant’s the Bahamas in 1946. Slide labeled Bryant Above Nicolls Town Andros Mar. '46.
Bahamas -- North America -- Nicholls Town, Andros

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 6:5
http://ufdc.ufl.edu/AA00028461/00001

Éditeur(s) : HAL CCSD
Résumé : TNF-Related Apoptosis-Inducing Ligand (TRAIL) is a well-known apoptosis inducer, which activates the extrinsic death pathway. TRAIL is pro-apoptotic on colon cancer cells, while not cytotoxic towards normal healthy cells. However, its clinical use is limited by cell resistance to cell death which occurs in approximately 50% of cancer cells. Short Chain Fatty Acids (SCFA) are also known to specifically induce apoptosis of cancer cells. In accordance, we have shown that food grade dairy propionibacteria induce intrinsic apoptosis of colon cancer cells, via the production and release of SCFA (propionate and acetate) acting on mitochondria. Here, we investigated possible synergistic effect between Propionibacterium freudenreichii and TRAIL. Indeed, we hypothesized that acting on both extrinsic and intrinsic death pathways may exert a synergistic pro-apoptotic effect. Whole transcriptomic analysis demonstrated that propionibacterial supernatant or propionibacterial metabolites (propionate and acetate), in combination with TRAIL, increased pro-apoptotic gene expression (TRAIL-R2/DR5) and decreased anti-apoptotic gene expression (FLIP, XIAP) in HT29 human colon cancer cells. The revealed synergistic pro-apoptotic effect, depending on both death receptors (TRAIL-R1/DR4, TRAIL-R2/DR5) and caspases (caspase-8, -9 and -3) activation, was lethal on cancer cells but not on normal human intestinal epithelial cells (HIEC), and was inhibited by Bcl-2 expression. Finally, milk fermented by P. freudenreichii induced HT29 cells apoptosis and enhanced TRAIL cytotoxic activity, as did P. freudenreichii DMEM culture supernatants or its SCFA metabolites. These results open new perspectives for food grade P. freudenreichii-containing products in order to potentiate TRAIL-based cancer therapy in colorectal cancer.
4 . International Symposium on Propionibacteria and Bibfidobacteria
Cork, Ireland

hal-01372131
https://hal.archives-ouvertes.fr/hal-01372131
PRODINRA : 371605

Éditeur(s) : HAL CCSD
Résumé : Food-grade dairy propionibacteria are nutraceutical producers. They release short chain fatty acids (SCFAs), folic acid and cobalamin, which play a role in intestinal physiology. SCFAs induce apoptosis via the mitochondrial death pathway. We investigated the potential of dairy propionibacteria-fermented products to synergize with drugs used in gastric and colorectal cancer.Fermented milk contained high and viable populations of propionibacteria. This product, as well as its cell-free supernatant, were tested in vitro on gastric HGT-1 and colic HT-29 cells with respect to apoptosis and synergy with known anti-cancer molecules, camptothecin and the human cytokine TRAIL (TNF Related Apoptosis Inducing Ligand). Viability was monitored and apoptosis quantified by Hoescht staining, ROS production, mitochondrial membrane potential perturbation and caspases activity assay. A transcriptomic study on genome-wide microarray was performed in collaboration with the company Miltenyi.Fermented milk induced cell death in both gastric and colon cancer cells. Characterization of cells revealed cell cycle arrest, drop in intracellular ATP, depolarization of mitochondria, translocation of key apoptosis proteins, processing of caspases and fragmentation of the nucleus. Interestingly, the fermented milk was shown to potentiate the cytotoxic effect of molecules used in cancer chemotherapy, camptothecin and TRAIL. The observed synergistic pro-apoptotic effect between TRAIL and propionibacterial SCFAs depended on death receptors and on caspases, was more lethal on cancer cells than on normal human intestinal epithelial cells (HIEC), and was inhibited by Bcl-2 expression. Transcriptomics revealed that propionibacterial metabolites boosted TRAIL-induced modulation of gene expression in human colon cancer cells.These results open new perspectives in the field of colon cancer cells prevention and/or treatment. The synergy with pro-apoptotic chemotherapy molecules suggests that such a fermented product, or the propionibacterium alone, may be proposed as a food supplement to enhance the effects of anticancer treatments.
The 2nd International conference on Cell Death In Cancer (CDIC)
La Baule, France

hal-01209622
https://hal.archives-ouvertes.fr/hal-01209622
PRODINRA : 261291