Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
CONTEXT: Chlordecone, an environmentally persistent organochlorine insecticide used intensively in banana culture in the French West Indies until 1993, has permanently polluted soils and contaminated foodstuffs. Consumption of contaminated food is the main source of exposure nowadays. We sought to identify main contributors to blood chlordecone concentration (BCC) and to validate an exposure indicator based on food intakes. MATERIAL AND METHODS: We used a food frequency questionnaire (FFQ) completed by a sample of 194 pregnant women to estimate their dietary exposure to chlordecone and compared it to blood levels. In a first approach, chlordecone daily intake was estimated as the product of daily eaten quantity of 214 foodstuffs, multiplied by their chlordecone content, and summed over all items. We then predicted individual blood chlordecone concentration with empirical weight regression models based on frequency of food consumption, and without contamination data. RESULTS: Among the 191 subjects who had BCC determination, 146 (76%) had detectable values and mean BCC was 0.86 ng/mL (range < LOD-13.2). Mean per capita dietary intake of chlordecone was estimated at 3.3 microg/day (range: 0.1-22.2). Blood chlordecone levels were significantly correlated with food exposure predicted from the empirical weight models (r=0.47, p<0.0001) and, to a lesser extent, with chlordecone intake estimated from food consumption and food contamination data (r=0.20, p=0.007). Main contributors to chlordecone exposure included seafood, root vegetables, and Cucurbitaceous. CONCLUSION: These results show that the Timoun FFQ provides valid estimates of chlordecone exposure. Estimates from empirical weight models correlated better with blood levels of chlordecone than did estimates from the dietary intake assessment.
ISSN: 0013-9351

inserm-00517109
http://www.hal.inserm.fr/inserm-00517109
http://www.hal.inserm.fr/inserm-00517109/document
http://www.hal.inserm.fr/inserm-00517109/file/Pesticide_exposureofpregnantwomeninGuadeloupe.pdf
DOI : 10.1016/j.envres.2009.10.015

Éditeur(s) : HAL CCSD Lippincott, Williams & Wilkins
Résumé : International audience
BACKGROUND: People in developed countries are widely exposed to low levels of organochlorine pesticides, polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs). Seafood is a major contributor to PCB exposure. Toxicity of those various pollutants to reproductive and endocrine functions raises questions about possible effects on fertility. We explored whether serum levels of these pollutants and seafood consumption were associated with the fertility of couples enrolled in a French birth cohort (PELAGIE). METHODS: Time-to-pregnancy was investigated in 3,421 pregnant women by asking how many months they had taken to conceive. Levels of 14 organochlorine pesticides, 12 PCBs, and 10 PBDE compounds were measured in cord blood serum from a random subcohort (n = 394). Mercury concentrations measured in maternal hair were considered as a potential coexposure. Fecundability odds ratios (ORs) were estimated from multivariate discrete-time Cox proportional hazard models. RESULTS: Shellfish consumption was associated with longer time-to-pregnancy (fecundability OR ≥twice/week vs. 0.410 µg/L vs. <0.266 µg/L, fecundability OR = 0.46 [0.32-0.66]). In multiple sensitivity analyses, reduced fecundability was most consistently associated with shellfish consumption, p,p'-DDE, total PCBs, PCB153, and PCB187. Models that simultaneously included multiple coexposure factors led to similar conclusions. CONCLUSIONS: Our findings were robust in sensitivity analyses, including analysis restricted to primiparous women. These results suggest that PCBs, p,p'-DDE, and other shellfish contaminants may impair human fertility.
ISSN: 1044-3983

inserm-00826533
http://www.hal.inserm.fr/inserm-00826533
DOI : 10.1097/EDE.0b013e31827f53ec
PUBMED : 23348067

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
BACKGROUND: Environmental exposures, including dietary contaminants, may influence the developing immune system. This study assesses the association between maternal pre-parturition consumption of seafood and wheeze, eczema, and food allergy in preschool children. Fish and shellfish were studied separately as they differ according to their levels of omega-3 polyunsaturated fatty acids (which have anti-allergic properties) and their levels of contaminants. METHODS: The PELAGIE cohort included 3421 women recruited at the beginning of pregnancy. Maternal fish and shellfish intake was measured at inclusion by a food frequency questionnaire. Wheeze, eczema, and food allergy were evaluated by a questionnaire completed by the mother when the child was 2 years old (n = 1500). Examination of the associations between seafood intake and outcomes took major confounders into account. Complementary sensitivity analyses with multiple imputation enabled us to handle missing data, due mostly to attrition. RESULTS: Moderate maternal pre-parturition fish intake (1 to 4 times a month) was, at borderline significance, associated with a lower risk of wheeze (adjusted OR = 0.69 (0.45-1.05)) before age 2, compared with low intake (< once/month). This result was not, however, consistent: after multiple imputation, the adjusted OR was 0.86 (0.63-1.17). Shellfish intake at least once a month was associated with a higher risk of food allergy before age 2 (adjusted OR = 1.62 (1.11-2.37)) compared to low or no intake (< once/month). Multiple imputation confirmed this association (adjusted OR = 1.52 (1.05-2.21)). CONCLUSIONS: This study suggests that maternal pre-parturition shellfish consumption may increase the risk of food allergy. Further large-scale epidemiologic studies are needed to corroborate these results, identify the contaminants or components of shellfish responsible for the effects observed, determine the persistence of the associations seen at age 2, and investigate potential associations with health effects observable at later ages, such as allergic asthma.
ISSN: 1476-069X

Droits : info:eu-repo/semantics/OpenAccess
inserm-00926282
http://www.hal.inserm.fr/inserm-00926282
http://www.hal.inserm.fr/inserm-00926282/document
http://www.hal.inserm.fr/inserm-00926282/file/1476-069X-12-102.pdf
DOI : 10.1186/1476-069X-12-102

Éditeur(s) : XXXIII International Symposium on New Species for Mediterranean Aquaculture, Alghero, 22-24 Avril 1998
Résumé : Mediterranean aquaculture development is now at a crossroads. The production of seabass and seabream has been increasing at a smart and constant pace for the last ten years. Nevertheless, it is still far behind the Northern European salmonid industry in terms of level of production, reduction of production costs and market internationalisation. Meanwhile, an in depth transformation of market conditions is ongoing in Europe which remains the main target market for Mediterranean aquaculture products. The most important issues are the soaring role of supermarkets in the distribution chain, the development of new processing techniques like pre-packed fresh fish, the growing importance of catering and the evolution of the consumer behaviour. Seafood consumer behaviour results from contradictory attitudes such as scrutiny of products' origin and farming process, research of the best value for money, desire of social image and need for easy to store and ready to cook fish. As in any other seafood industry, product differentiation has become a pre-requisite to fit consumer's demand and reach new consumers thanks to market segmentation. From a theoretical point of view, two kinds of differentiation have to be taken into account: horizontal differentiation basedon the diversity of presentations of the same quality and vertical differentiation based on a hierarchy of quality. Examining precedents in the poultry industry and salmonid industry make it possible to assess the potential role new species may play in product differentiation. In the case of Mediterranean aquaculture, an analysis of the market structure for fresh fish in France, Italy and Greece reveals two different ways of product differentiation: new well known species with a good image for connoisseur markets and standard quality fish provided by species with high growth potential for the mass market. In any case, particular attention has to be given to reputation, long term production costs and capacity to provide a large range of products. [NOT CONTROLLED OCR]

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1998/acte-4008.pdf
http://archimer.ifremer.fr/doc/00000/4008/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Ciguatera Fish Poisoning (CFP) is a non-bacterial seafood poisoning well characterized in the remote archipelagos of French Polynesia, yet poorly documented in the Society archipelago, most notably on Moorea, the second most populated island in French Polynesia, which counts a high proportion of fishermen fishing on a regular basis. To address this knowledge gap, a holistic study of the ciguatera issue was conducted on Moorea. First, ciguatera risk was analysed in terms of incidence rate, fish species most commonly involved and risk stratification in Moorea lagoon based on 2007–2013 epidemiological data. A mean incidence rate of 8 cases per 10,000 inhabitants for the study period and an average under-reporting rate of 54% were found. Taking into account hospitalization and medication fees, and loss of productive days, the health-related costs due to CFP were estimated to be USD $1613 and $749 for each reported and unreported case, respectively, with an overall cost of USD $241,847 for the study period. Comparison of the present status of CFP on Moorea with a risk map established in the late 1970’s showed that the spatial distribution of the risk has stayed relatively stable in time, with the north shore of the island remaining the most prone to ciguatera. Evaluation of the current knowledge on CFP among different populations groups, i.e. fishermen, residents and visitors, was also conducted through direct and indirect interviews. About half of the fishermen interviewed were actually able to identify risky fishing areas. While, overall, the CFP risk perception in the fishing community of Moorea seemed accurate, although not scientifically complete, it was sufficient for the safe practice of their fishing activities. This may be due in part to adaptive responses adopted by 36% of the fishermen interviewed, such as the avoidance of either high-risk fishing sites or toxic species. At the residents and visitors’ level, the study points out a striking lack of awareness of the CFP issue among visitors, as compared to local residents. Indeed, less than 25% of Moorea visitors vs. an average of 98% in residents were aware of CFP or of its presence on the island. Interestingly, evaluation of the fish consumption preferences showed that 70% of visitors do not consume lagoon fish during their stay, not for fear of CFP, but mainly due to the lack of availability of these species in recreational facilities or because they have nutritional preference for pelagic fish. This lack of awareness, along with the report by several CFP patients of the consumption of fish species yet banned for sale, stress the need for improved communication efforts on this critical issue among both residents and visitors on Moorea. The implementation of a public outreach strategy is proposed, based on both existing information networks and low-cost communication actions through information displays at various strategic locations, e.g. Tahiti-Faa’a international airport, the ferry boat station, recreational facilities, as well as the major trading points on Moorea Island.
ISSN: 1568-9883

hal-01391648
https://hal-univ-perp.archives-ouvertes.fr/hal-01391648
DOI : 10.1016/j.hal.2016.10.003

Résumé : In the French West Indies islands, the transfer of chlordecone (kepone) from treated grounds towards the marine environment has been proved since the beginning of 2000s. In 2008, a maximal residue limit (MRL) was set at 20 µg / kg wet weight in fish and seafood, and therefore intensified the concern about the risks of high human exposure to the pesticide due to the consumption of contaminated marine products. To answer this concern, several sampling cruises were carried by public authorities and by Ifremer in order to analyze the contamination of the fish fauna around the Guadeloupe island. The data collected within these surveys improved our knowledge on the characteristics of the contamination of fish fauna and allowed to assess the distribution of this contamination in relation with optional geographical plans of the marine area around the Guadeloupe island. Further, this study was completed by an assessment of the fishery activity in areas which are the more exposed to the chlordecone contamination, taking into account data from a fishery observatory which has been set up in the archipelago since 2007. The results allow to precise two main characteristics of distribution of the contamination: its spatial and specific dimensions. About the spatial aspect, contamination of the fish fauna is centred on marine areas which are closely downstream contaminated watersheds. Concerning the marine fauna, two species groups are particularly exposed: the very coastal ones, particularly those living at or close to the mouth of rivers, and crustaceans wherever they live. Among fishes, the most contaminated species belong to many various groups which are present in the very coastal belt, more or less regularly. Lastly, this study provided orders of magnitude on the relative part of the fishery activity around the archipelagos for which the contamination is of great concern.
Aux Antilles, l’existence d’un transfert de la molécule de chlordécone des sols traités vers le milieu marin est avérée depuis le début des années 2000. L’établissement d’une limite maximale de résidus à 20 µg/kg pf pour tous les produits marins en 2008 y a intensifié la préoccupation vis-à-vis des risques d’exposition des populations humaines par les produits de la pêche. Pour répondre à cette préoccupation, depuis 2008, plusieurs campagnes d’échantillonnage ont été réalisées par les services de l’Etat (DAAF) et par l’Ifremer pour analyser la contamination de la faune halieutique autour de la Guadeloupe. Les données collectées de 2008 à 2011 par ces plans d’observation ont été utilisées pour actualiser les connaissances sur les caractéristiques de la contamination de la faune halieutique autour de la Guadeloupe, et analyser cette distribution en référence à différents schémas de segmentation du domaine marin. L’étude a été complétée par une analyse de l’activité halieutique dans les secteurs les plus sensibles à la contamination, à partir des données du système d’informations halieutiques déployé dans l’archipel depuis 2007. L’analyse a permis de préciser deux traits majeurs de cette distribution : sa dimension spatiale et son caractère spécifique. Sur le plan spatial, la contamination de la faune halieutique est centrée sur les espaces maritimes situées immédiatement en aval des bassins versants contenant des sols contaminés. Sur le plan faunistique, deux groupes apparaissent particulièrement sensibles, les espèces très côtières, en particulier celles fréquentant les embouchures des cours d’eau, et les crustacés, quelque soit leur milieu de vie. Chez les poissons, parmi les espèces contaminées, on trouve un large cortège d’espèces fréquentant plus ou moins régulièrement la bande littorale. Enfin, l’étude a permis de fournir des ordres de grandeur sur la part de l’activité halieutique de l’archipel directement concernée par cette pollution.

Droits : 2013 Ifremer
http://archimer.ifremer.fr/doc/00136/24762/22840.pdf
http://archimer.ifremer.fr/doc/00136/24762/