Éditeur(s) : HAL CCSD Springer
Résumé : International audience
One of the most important topics that occupy public health problems is the air quality. That is the reason why mechanical ventilation and air handling units (AHU) were imposed by the different governments in the collective or individual buildings. Many buildings create an artificial climate using heating, ventilation and airconditioning (HVAC) systems. Among the existing aerosols in the indoor air, we can distinguish the bioaerosol with biological nature such as bacteria, viruses, fungi. Respiratory viral infections are a major public health issue because they are usually highly infective. We spend about 90% of our time in closed environments such as homes, workplaces or transport. Some studies have shown that AHU contribute to the spread and transport of viral particles within buildings. The aim of this work is to study the characterization of viral bioaerosols in indoor environments and to understand the fate of mengovirus eukaryote RNA virus on glass fiber filter F7 used in AHU. In this study, a setup close to reality of AHU system was used. The mengovirus aerosolized was characterized and measured with the Electrical Low Pressure Impact (ELPI) and the Scanner Mobility Particle Size (SMPS) and detected with RT-qPCR. The results about quantification and the level of infectivity of mengovirus on the filter and in the biosampler showed that mengovirus can pass through the filter and remain infectious upstream and downstream the system. Regarding the virus effectiveness on the filter under a constant air flow, and mengovirus was remained infectious during 10 hours after aerosolization.
ISSN: 1867-0334

hal-01636427
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01636427
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01636427/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01636427/file/Fate%20of%20mengovirus%20on%20fiberglass%20filter_accepted.pdf
DOI : 10.1007/s12560-017-9310-8

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
The implication of oxidative stress as primary mechanism inducing doxorubicin (DOX) cardiotoxicity is still questionable as many in vitro studies implied supra-clinical drug doses or unreliable methodologies for reactive oxygen species (ROS) detection. The aim of this study was to clarify whether oxidative stress is involved in compliance with the conditions of clinical use of DOX, and using reliable tools for ROS detection. We examined the cytotoxic mechanisms of 2 μM DOX 1 day after the beginning of the treatment in differentiated H9c2 rat embryonic cardiac cells. Cells were exposed for 2 or 24 h with DOX to mimic a single chronic dosage or to favor accumulation, respectively. We found that apoptosis was prevalent in cells exposed for a short period with DOX: cells showed typical hallmarks as loss of anchorage ability, mitochondrial hyperpolarization followed by the collapse of mitochondrial activity, and nuclear condensation. Increasing the exposure period favored a shift to necrosis as the cells preferentially exhibited early DNA impairment and nuclear swelling. In either case, measuring the fluorescence lifetime of 1-pyrenebutyric acid or the intensities of dihydroethidium or amplex red showed a consistent pattern in ROS production which was a slight increased level far from representative of an oxidative stress. Moreover, pre-treatment with dexrazoxane provided a cytoprotective effect although it failed to detoxify ROS. Our data support that oxidative stress is unlikely to be the primary mechanism of DOX cardiac toxicity in vitro.
ISSN: 0300-8177

hal-01285736
https://hal-univ-perp.archives-ouvertes.fr/hal-01285736
DOI : 10.1007/s11010-016-2653-x

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
The structure and dynamic evolution of a mountain belt piedmont are controlled by strong interactions between tectonics, surface processes (erosion, sedimentation), and climate. Studying these couplings relies on detailed geometric and kinematic analysis of morphostructural markers (folds, faults, terraces, alluvial surfaces) and analysis of syntectonic sedimentation. To study quantitatively how these markers form, evolve and record deformation, we developed a new analogue modelling approach using a specific composite granular material. The originality stands in the simultaneous modelling of orogenic deformation mechanisms and erosion-transport-sedimentation processes, but also in the use of techniques allowing quantitative measurement of morphostructural evolution. This methodology opens new perspectives in the fields of geomorphology (relief dynamics), seismotectonics (study of active faults), and sedimentology (including sequential stratigraphy).
ISSN: 0010-7999

hal-00411972
https://hal.archives-ouvertes.fr/hal-00411972
DOI : 10.1016/j.crte.2008.01.005

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Ecosystems are commonly affected by natural, episodic disturbances that can abruptly and drastically alter communities. Although it has been shown that resilient ecosystems can eventually recover to pre-disturbed states, the extent to which communities in early stages of recovery could be affected by multiple anthropogenic stressors is poorly understood. Pervasive and rising anthropogenic stressors in coastal marine systems that could interactively affect the recovery of these systems following natural disturbances include high sedimentation, nutrient enrichment, and overfishing. Using a 6-month field experiment, we examined the effects of all combinations of these three stressors on key functional groups in the benthic community growing on simulated, post-disturbance reef patches within a system recovering from large-scale natural disturbances (corallivorous seastar outbreak and cyclone). Our study revealed that sedimentation, nutrient enrichment, and overfishing (simulated using exclusion cages) interactively affected coral survival and algal growth, with taxon-specific effects at multiple scales. First, our treatments affected corals and algae differently, with sedimentation being more detrimental to macroalgal growth but less detrimental to coral (Porites rus) survival in caged plots, driving significant interactions between sedimentation and caging for both taxa. We also observed distinct responses between coral species and between algal functional groups, with the most extensive responses from algal turf biomass, for which sedimentation suppressed the synergistic (positive) combined effect of nutrient enrichment and caging. Our findings suggest that different combinations of ubiquitous anthropogenic stressors, related to either sea- or land-based activities, interactively influence community recovery from disturbance and may alter species compositions in the resulting community. Our findings further suggest that anthropogenic stressors could promote further degradation of coral reefs following natural disturbances by inhibiting recovery to coral-dominated states that provide vital ecosystem services to coastal populations worldwide.
ISSN: 0722-4028

hal-01430977
https://hal-univ-perp.archives-ouvertes.fr/hal-01430977
DOI : 10.1007/s00338-016-1489-x

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Few studies have investigated the influence of environmental conditions on the within-treevariation in Eucalyptus wood traits. The genotype and environment effects and their interactionsinfluence the wood properties. Their evaluations are crucial to estimate the genotype values andto select with efficiency. Thus, the aim of this study was to better understand the effect ofground slope and wind speed on the spatial variation of basic density (ρ), stiffness (MOE) andmicrofibril angle (MFA) of Eucalyptus wood. Wood discs cut along the trunk were sampledfrom 150 six-year-old Eucalyptus grandis x E. urophylla hybrids growing in 3 contrastinggrowing conditions influenced by ground slope and wind regime. Near Infrared (NIR)calibrations previously developed for ρ, MOE and MFA were used to predict in our discs. 2-Dplots presenting the spatial variation of predicted wood traits were compared. The higher theground slope, the greater the magnitude of radial variation in ρ, principally in the medium zoneof the trunk. The spatial variation of wood stiffness seems to be sensitive to two environmentalconditions. The MFA radial decreases were more pronounced where the wind speed was higher.At the base and top of the trees, however, there was no significant effect of growing conditionson the radial variation of the wood properties considered here.
ISSN: 0931-1890

hal-01451896
https://hal.archives-ouvertes.fr/hal-01451896
https://hal.archives-ouvertes.fr/hal-01451896/document
https://hal.archives-ouvertes.fr/hal-01451896/file/Art_Gril_al_Spatial_variation_wood_density_2016.pdf
DOI : 10.1007/s00468-015-1327-8

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Algorithms issued from the NonLinear Galerkin method have been used in many situations and with different discretizations for the resolution of evolutionary nonlinear equations. The main idea of these methods is to use a splitting of the solution in order to model the equation. According to the splitting of the solution, a splitting of the equation is obtained. The modeling principle is to freeze terms which have a small time variation. In this work we use wavelet discretizations of the 2-D Burgers equations and compare the results with the hierarchical finite elements method. The numerical tests indicate that wavelets give better results than finite elements
ISSN: 0885-7474

hal-00383423
https://hal.archives-ouvertes.fr/hal-00383423
DOI : 10.1007/s10915-004-4806-4

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Disentangling the autotrophic and heterotrophic components of soil CO2 efflux is critical to understanding the role of soil system in terrestrial carbon (C) cycling. In this study, we combined a stable C-isotope natural abundance approach with the trenched plot method to determine if root exclusion significantly affected the isotopic composition (δ13C) of soil CO2 efflux (RS). This study was performed in different forest ecosystems: a tropical rainforest and two temperate broadleaved forests, where trenched plots had previously been installed. At each site, RS and its δ13C (δ13CRs) tended to be lower in trenched plots than in control plots. Contrary to RS, δ13CRs differences were not significant. This observation is consistent with the small differences in δ13C measured on organic matter from root, litter and soil. The lack of an effect on δ13CRs by root exclusion could be from the small difference in δ13C between autotrophic and heterotrophic soil respirations, but further investigations are needed because of potential artefacts associated with the root exclusion technique.
ISSN: 0032-079X

bioemco-00353850
https://hal-bioemco.ccsd.cnrs.fr/bioemco-00353850
DOI : 10.1007/s11104-008-9844-5

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
ISSN: 1433-7541

hal-01279720
https://hal.archives-ouvertes.fr/hal-01279720

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : A detailed and integrated geologic–hydraulic–geophysical–geochemical study of groundwater flow in the near-vicinity of a borehole drilled into fractured and karstified limestone demonstrates the power of such an integrated approach in localising and characterising preferential groundwater flow pathways and ambient borehole flow. The study, conducted in the vicinity of a 100-m-deep research borehole on the island of Mallorca, achieves such characterisation on a scale from millimetres to tens of metres in scale. More specifically, it adds single packer and open-hole pumping test interpretations to the results obtained during fluid logging, impeller flowmeter testing, borehole imaging, core descriptions and an innovative fracture analysis. This approach allows the delineation of the main flowing features and showed that such features are directly or indirectly linked to karst phenomena. Understanding this complex flow system is critical for an appropriate assessment of groundwater resources and the design of sustainable groundwater production schemes.
ISSN: 1431-2174

hal-00404921
https://hal.archives-ouvertes.fr/hal-00404921
DOI : 10.1007/s10040-006-0086-4

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
The anisotropy of vibrational properties influences the acoustic behaviour of wooden pieces and their dependence on grain angle (GA). As most pieces of wood include some GA, either for technological reasons or due to grain deviations inside trunks, predicting its repercussions would be useful. This paper aims at evaluating the variability in the anisotropy of wood vibrational properties and analysing resulting trends as a function of orientation. GA dependence is described by a model based on transformation formulas applied to complex compliances, and literature data on anisotropic vibrational properties are reviewed. Ranges of variability, as well as representative sets of viscoelastic anisotropic parameters, are defined for mean hardwoods and softwoods and for contrasted wood types. GA-dependence calculations are in close agreement with published experimental results and allow comparing the sensitivity of different woods to GA. Calculated trends in damping coefficient (tanδ) and in specific modulus of elasticity (E′/ρ) allow reconstructing the general tanδ-E′/ρ statistical relationships previously reported. Trends for woods with different mechanical parameters merge into a single curve if anisotropic ratios (both elastic and of damping) are correlated between them, and with axial properties, as is indicated by the collected data. On the other hand, varying damping coefficient independently results in parallel curves, which coincide with observations on chemically modified woods, either "artificially", or by natural extractives.
ISSN: 0043-7719

hal-00804242
https://hal.archives-ouvertes.fr/hal-00804242
https://hal.archives-ouvertes.fr/hal-00804242/document
https://hal.archives-ouvertes.fr/hal-00804242/file/Anisotropy_wood_variational_properties_Bremaud_al_2011.pdf
DOI : 10.1007/s00226-010-0393-8

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
o abstract
ISSN: 0920-9069

hal-01546171
https://hal.archives-ouvertes.fr/hal-01546171

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : A preliminary version appeared in the 18th ACM-SIAM Symposium on Discrete Algorithms, pp. 746- 755, 2007
International audience
The Voronoi diagram of a finite set of objects is a fundamental geometric structure that subdivides the embedding space into regions, each region consisting of the points that are closer to a given object than to the others. We may define various variants of Voronoi diagrams depending on the class of objects, the distance function and the embedding space. In this paper, we investigate a framework for defining and building Voronoi diagrams for a broad class of distance functions called Bregman divergences. Bregman divergences include not only the traditional (squared) Euclidean distance but also various divergence measures based on entropic functions. Accordingly, Bregman Voronoi diagrams allow one to define information-theoretic Voronoi diagrams in sta- tistical parametric spaces based on the relative entropy of distributions. We define several types of Bregman diagrams, establish correspondences between those diagrams (using the Legendre transformation), and show how to compute them efficiently. We also introduce extensions of these diagrams, e.g. k-order and k-bag Bregman Voronoi diagrams, and introduce Bregman triangulations of a set of points and their connection with Bregman Voronoi diagrams. We show that these triangulations capture many of the properties of the celebrated Delaunay triangulation.
ISSN: 0179-5376

hal-00488441
https://hal.archives-ouvertes.fr/hal-00488441
https://hal.archives-ouvertes.fr/hal-00488441/document
https://hal.archives-ouvertes.fr/hal-00488441/file/BVD-DCG.pdf

Éditeur(s) : HAL CCSD Springer Verlag
Résumé :  
Genetic variation for intrinsic water use efficiency (W i) and related traits was estimated in a full-sib family of Quercus robur L. over 3 years. The genetic linkage map available for this F1 family was used to locate quantitative trait loci (QTL) for W i, as estimated by leaf carbon stable isotope composition (δ 13C) or the ratio of net CO2 assimilation rate (A) to stomatal conductance to water vapour (g w) and related leaf traits. Gas exchange measurements were used to standardize estimates of A and g w and to model the sensitivity of g w to leaf-to-air vapour pressure deficit (sgVPD). δ 13C varied by more than 3‰ among the siblings, which is equivalent to 40% variation of W i. Most of the studied traits exhibited high clonal mean repeatabilities (>50%; proportion of clonal mean variability in global variance). Repeatabilities for δ 13C, leaf mass per area (LMA) and leaf nitrogen content were higher than 70%. For δ 13C, ten QTLs were detected, one of which was detected repeatedly for all 3 years and consistently explained more than 20% of measured variance. Four genomic regions were found in which co-localizing traits linked variation in W i to variations in leaf chlorophyll and nitrogen content, LMA and sgVPD. A positive correlation using clonal means between δ 13C and A/g w, as well as a co-localisation of QTL detected for both traits, can be seen as validation of the theoretical model linking the genetic architecture of these two traits.
ISSN: 1614-2942

hal-01032066
https://hal.archives-ouvertes.fr/hal-01032066
DOI : 10.1007/s11295-007-0107-z

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Many iterative processes can be interpreted as discrete dynamical systems and, in certain cases, they correspond to a time discretisation of differential systems. In this article the authors propose generating numerical methods in numerical linear algebra by modelling the linear system to be solved as a given state of a dynamical system; the solution can be reached asymptotically, as a (asymptotically stable) steady state, but also as a finite time (shooting methods). In that way, any (stable) numerical scheme for the integration of such a problem can be presented as a method for solving linear systems. The authors discuss aspects of this approach, which allows them to recover some known methods but also to introduce new ones. Finally, some convergence results and numerical illustrations are presented.
ISSN: 1017-1398

hal-00730194
https://hal.archives-ouvertes.fr/hal-00730194

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
ISSN: 0049-6979

halshs-00681736
https://halshs.archives-ouvertes.fr/halshs-00681736

Éditeur(s) : HAL CCSD Springer International Publishing
Résumé : International audience
15th French-Japanese Oceanography Symposium of Oceanography “Marine Productivity, Perturbations and Resilience of Socio-Ecosystems

ISBN : 978-3-319-13878-7-38
hal-01212907
https://hal-univ-perp.archives-ouvertes.fr/hal-01212907

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Extractives can affect vibrational properties tanδ (damping coefficient) and E'/ρ (specific Young's modulus) but this is highly dependent on species, compounds, and cellular locations. This paper investigates such effects for African Padauk (Pterocarpus soyauxii Taub.), a tropical hardwood with high extractives content and a preferred material for xylophones. 5 groups of 26 heartwood specimens with large, yet comparable, ranges in vibrational properties were extracted in different solvents. Changes in vibrational properties were set against yields of extracts and evaluation of their cellular location. Methanol (ME) reached most of compounds (13%), located about half in lumen and half in cell-wall. Water solubility was extremely low. tanδ and E'/ρ were very strongly related (R2≥0.93), but native wood had abnormally low values of tanδ, while extraction shifted this relation towards higher tanδ values. ME extracted heartwood became in agreement with the average of many species, and close to sapwood. Extractions increased tanδ as much as 60%, irrespective of minute moisture changes or of initial properties. Apparent E'/ρ was barely changed (+2% to -4%) but, after correcting the mass contribution of extracts, was in fact slightly reduced (down to -10% for high E'/ρ), and increasingly so for specimens with low initial values of E'/ρ.
ISSN: 0043-7719

hal-00804236
https://hal.archives-ouvertes.fr/hal-00804236
https://hal.archives-ouvertes.fr/hal-00804236/document
https://hal.archives-ouvertes.fr/hal-00804236/file/Effect_extractives_vibrational_properties_Bremaud_al.pdf
DOI : 10.1007/s00226-010-0337-3

Éditeur(s) : HAL CCSD Springer
Résumé : Borehole logs provide in situ information about the fluctuations of petrophysical properties with depth and thus allow the characterization of the crustal heterogeneities. A detailed investigation of these measurements may lead to extract features of the geological media. In this study, we suggest a regularity analysis based on the continuous wavelet transform to examine sonic logs data. The description of the local behavior of the logs at each depth is carried out using the local Hurst exponent estimated by two (02) approaches: the local wavelet approach and the average-local wavelet approach. Firstly, a synthetic log, generated using the random midpoints displacement algorithm, is processed by the regularity analysis. The obtained Hurst curves allowed the discernment of the different layers composing the simulated geological model. Next, this analysis is extended to real sonic logs data recorded at the Kontinentales Tiefbohrprogramm (KTB) pilot borehole (Continental Deep Drilling Program, Germany). The results show a significant correlation between the estimated Hurst exponents and the lithological discontinuities crossed by the well. Hence, the Hurst exponent can be used as a tool to characterize underground heterogeneities.
ISSN: 1866-7411

hal-00617470
https://hal.archives-ouvertes.fr/hal-00617470
DOI : 10.1007/s12517-010-0129-y

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
The purpose of this investigation was to characterize the management and prognosis of severe Pneumocystis jirovecii pneumonia (PJP) in human immunodeficiency virus (HIV)-negative patients. An observational cohort study of HIV-negative adults with PJP documented by bronchoalveolar lavage (BAL) through Gomori-Grocott staining or immunofluorescence, admitted to one intensive care unit (ICU) for acute respiratory failure, was undertaken. From 1990 to 2010, 70 patients (24 females, 46 males) were included, with a mean age of 58.6 ± 18.3 years. The mean Simplified Acute Physiology Score (SAPS)-II was 36.9 ± 20.4. Underlying conditions included hematologic malignancies (n = 21), vasculitis (n = 13), and solid tumors (n = 13). Most patients were receiving systemic corticosteroids (n = 63) and cytotoxic drugs (n = 51). Not a single patient received trimethoprim-sulfamethoxazole as PJP prophylaxis. Endotracheal intubation (ETI) was required in 42 patients (60.0 %), including 38 with acute respiratory distress syndrome (ARDS). In-ICU mortality was 52.9 % overall, reaching 80.9 % and 86.8 %, respectively, for patients who required ETI and for patients with ARDS. In the univariate analysis, in-ICU mortality was associated with SAPS-II (p = 0.0131), ARDS (p < 0.0001), shock (p < 0.0001), and herpes simplex virus (HSV) or cytomegalovirus (CMV) on BAL (p = 0.0031). In the multivariate analysis, only ARDS was associated with in-ICU mortality (odds ratio [OR] 23.4 [4.5-121.9], p < 0.0001). PJP in non-HIV patients remains a serious disease with high in-hospital mortality. Pulmonary co-infection with HSV or CMV may contribute to fatal outcome.
ISSN: 0934-9723

inserm-00872789
http://www.hal.inserm.fr/inserm-00872789
DOI : 10.1007/s10096-012-1730-7
PUBMED : 22930407

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
ISSN: 0927-6947

hal-00507830
https://hal.archives-ouvertes.fr/hal-00507830