Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The origin of plate tectonics is one of the most fundamental issues in earth and planetary sciences. Laboratory experiments indicate that the viscosity of silicate rocks is so strongly temperature-dependent that the entire surface of the Earth should be one immobile rigid plate. The rheology of oceanic lithosphere is, however, still poorly understood, and there exist few constraints on the temperature dependency of viscosity on the field scale. Here we report a new kind of observational constraint based on the geoid along oceanic fracture zones. We identify a large number of conspicuous small-scale geoid anomalies, which cannot be explained by the standard evolution model of oceanic lithosphere, and estimate their source density perturbations using a new Bayesian inversion method. Our results suggest that they are caused most likely by small-scale convection involving temperature perturbations of ∼300 K±100 K∼300 K±100 K. Such thermal contrast requires the activation energy of mantle viscosity to be as low as View the MathML source100±50 kJmol−1 in case of diffusion creep, and View the MathML source225±112 kJmol−1 in case of dislocation creep, substantially reducing the thickness of the stiffest part of oceanic lithosphere. Oceanic lithosphere may thus be broken and bent much more easily than previously thought, facilitating the operation of plate tectonics.
ISSN: 0012-821X

hal-01467827
https://hal.archives-ouvertes.fr/hal-01467827
DOI : 10.1016/j.epsl.2016.05.027

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Two-dimensional simulations using a thermomechanical model based on a finite-difference method on a staggered grid and a marker in cell method are performed to study the plume-lithosphere interaction beneath moving plates. The plate and the convective mantle are modelled as a homogeneous peridotite with a Newtonian temperature- and pressure-dependent viscosity. A constant velocity, ranging from 5 to 12.5 cm yr−1, is imposed at the top of the plate. Plumes are generated by imposing a thermal anomaly of 150 to 350 K on a 50 km wide domain at the base of the model (700 km depth); the plate atop this thermal anomaly is 40 Myr old. We analyse (1) the kinematics of the plume as it impacts the moving plate, (2) the dynamics of time-dependent small-scale convection (SSC) instabilities developing in the low-viscosity layer formed by spreading of hot plume material at the base of the lithosphere and (3) the resulting thermal rejuvenation of the lithosphere. The spreading of the plume material at the base of the lithosphere, characterized by the ratio between the maximum down- and upstream horizontal (dimensionless) velocities in the plume-fed sublithospheric layer, Peup/Pedown depends on the ratio between the maximum plume upwelling velocity and the plate velocity, Peplume/Peplate. For fast plate velocities and sluggish plumes (low Peplume/Peplate), plate motion drags most plume material and downstream flow is dominant. As Peplume/Peplate increases, an increasing part of the plume material flows upstream. SSC systematically develops in the plume-fed sublithospheric layer, downstream from the plume. Onset time of SSC decreases with the Rayleigh number. For vigorous plumes, it does not depend on plate velocity. For more sluggish plumes, however, variations in the plume spreading behaviour at the base of the lithosphere result in a decrease in the onset time of SSCs with increasing plate velocity. In any case, SSC results in uplift of the isotherm 1573 K by up to 20 km relative to its initial equilibrium depth at the impact point.
ISSN: 0956-540X

hal-00856763
https://hal.archives-ouvertes.fr/hal-00856763
DOI : 10.1093/gji/ggt128

Éditeur(s) : HAL CCSD IOS Press
Résumé : International audience
The aim of the present study was to test the effects of hydroxyurea (HU) therapy on clinical, hematological and hemorheological parameters in adult patients with sickle cell anemia (SCA). Hematological and hemorheological parameters were measured in 28 SCA patients before HU therapy (i.e., baseline) and at 6, 12 and 24 months of treatment. RBC deformability was determined by ektacytometry at 30 Pa. RBC aggregation properties were investigated by light-backscatter method. Blood viscosity was measured at 225 s-1 by a cone-plate viscometer. The rates of vaso-occlusive crises and acute chest syndrome were lower at 1 and 2 years of HU therapy compared to baseline. The proportion of patients with leg ulcers tended to decrease after 2 years of treatment. Hemoglobin oxygen saturation improved with HU therapy. HU therapy induced a decrease of platelet and white blood cell counts and a rise in fetal hemoglobin level and mean cell volume. While hemoglobin concentrations increased under HU, blood viscosity remained unchanged all along the study. RBC deformability increased over baseline values at 6 months of HU therapy and continued to rise until the end of the follow-up period. In conclusion, the improvement in RBC deformability probably compensates the increase of hemoglobin on blood viscosity and participates to the improvement of the clinical status of patients.
ISSN: 1386-0291

hal-01668327
https://hal.univ-antilles.fr/hal-01668327
DOI : 10.3233/CH-170280

Éditeur(s) : HAL CCSD Ferrata Storti Foundation
Résumé : International audience
BACKGROUND: Little is known about the effects of blood rheology on the occurrence of acute chest syndrome and painful vaso-occlusive crises in children with sickle cell anemia and hemoglobin SC disease. DESIGN AND METHODS: To address this issue, steady-state hemorheological profiles (blood viscosity, red blood cell deformability, aggregation properties) and hematologic parameters were assessed in 44 children with sickle cell anemia and 49 children with hemoglobin SC disease (8-16 years old) followed since birth. Clinical charts were retrospectively reviewed to determine prior acute chest syndrome or vaso-occlusive episodes, and rates of these complications were calculated. RESULTS: Multivariate analysis revealed that: 1) a higher steady-state blood viscosity was associated with a higher rate of vaso-occlusive crises in children with sickle cell anemia, but not in children with hemoglobin SC disease; 2) a higher steady-state red blood cell disaggregation threshold was associated with previous history of acute chest syndrome in children with hemoglobin SC disease and boys with sickle cell anemia. CONCLUSIONS: Our results indicate for the first time that the red blood cell aggregation properties may play a role in the pathophysiology of acute chest syndrome in children with hemoglobin SC disease and boys with sickle cell anemia. In addition, whereas greater blood viscosity is associated with a higher rate of vaso-occlusive crises in children with sickle cell anemia, no association was found in children with hemoglobin SC disease, underscoring differences in the etiology of vaso-occlusive crises between sickle cell anemia and hemoglobin SC disease.
ISSN: 0390-6078

inserm-00849038
http://www.hal.inserm.fr/inserm-00849038
http://www.hal.inserm.fr/inserm-00849038/document
http://www.hal.inserm.fr/inserm-00849038/file/inserm-00849038.pdf
DOI : 10.3324/haematol.2012.066670

Éditeur(s) : HAL CCSD
Résumé : International audience
The main purpose of this note is to propose viscosity approximation methods which amount to selecting a particular fixed-point of a given nonexpansive self mapping in a general Hilbert space. The connection with the selection principles of Attouch, in the context of convex minimization and monotone inclusion problems, is made and an application to a semi-coercive elliptic problem is then stated. Key words: nonexpansive mappings, fixed-points, monotone operators, iterative methods, convex optimization, selection, penalty ...
Lecture notes in economics and mathematical systems

hal-00776623
https://hal.univ-antilles.fr/hal-00776623

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
OBJECTIVES:Blood rheology plays a key role in the pathophysiology of sickle cell anaemia (SS) and sickle cell haemoglobin C disease (SC), but its evolution over the lifespan is unknown.MATERIALS AND METHODS:Blood viscosity, red blood cell (RBC) deformability and aggregation, foetal haemoglobin (HbF) and haematocrit were measured in 114 healthy individuals (AA), 267 SS (161 children + 106 adults) and 138 SC (74 children + 64 adults) patients.RESULTS:Our results showed that 1) RBC deformability is at its maximal value during the early years of life in SS and SC populations, mainly because HbF level is also at its peak, 2) during childhood and adulthood, hydroxycarbamide treatment, HbF level and gender modulated RBC deformability in SS patients, independently of age, 3) blood viscosity is higher in older SS and SC patients compared to younger ones and 4) haematocrit decreases as SS patients age.CONCLUSION:The hemorheological changes detected in older patients could play a role in the progressive development of several chronic disorders in sickle cell disease, whose prevalence increases with age. Retarding these age-related haemorheological impairments, by using suitable drugs, may minimize the risks of vaso-occlusive events and chronic disorders.
ISSN: 1932-6203

Droits : http://creativecommons.org/licenses/by/
hal-01669747
https://hal.univ-antilles.fr/hal-01669747
DOI : 10.1371/journal.pone.0158182
PUBMED : 27355589
PUBMEDCENTRAL : PMC4927160

Éditeur(s) : HAL CCSD Yokohama
Résumé : International audience
We make use of the viscosity technique to develop a convergent method for approximating a common element of the set of fixed points of a demicontractive operator and the set of solutions of a monotone equilibrium problem. The proposed algorithm is obtained by coupling a modified hybrid steepest descent method with the extragradient algorithm. Under mild conditions, the strong convergence of the sequences generated by the algorithm is obtained. Using this result we obtain two corollaries which improve or develop several corresponding results in this field.
Journal of Nonlinear and Convex Analysis

hal-00779988
https://hal.univ-antilles.fr/hal-00779988

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
In this paper, the generalized Stokes problem αu−νΔu+∇p=f, ∇u=0, is considered, where ν denotes the kinematic viscosity, α is a positive parameter proportional to the inverse of the time-step, and the source term f gathers the external forcing, the nonlinear term, and the explicit part of the linear term. The system is derived from a time discretization for the Navier-Stokes equation governing the motion of a two-dimensional incompressible fluid. A domain decomposition numerical method is developed for solving the system. The original domain is divided into several nonoverlapping subdomains, and in each subdomain the concerned equations are discretized by certain finite element methods. A new feature of the method is that the pressure p is required to be piecewise linear rather than piecewise constant, so that the nonphysical oscillations in the solution using piecewise linear pressure are eliminated. However, a difficulty in using piecewise linear pressure is that the Stokes problem in each subdomain involves Dirichlet boundary conditions on pressure at the interface, which is not a real Stokes problem. To avoid the difficulty, a modification is proposed which removes the continuity conditions on the pressure across the interface. In this way, the Stokes problem in each subdomain has only Dirichlet boundary conditions on the velocity. Formulations and discussions for both the methods are presented, which shows that the modified method is simpler than the original one. Numerical experiments are displayed to show the efficiency of the methods, especially that the modified method has the same accuracy as the original one.
ISSN: 0749-159X

hal-00730200
https://hal.archives-ouvertes.fr/hal-00730200

Éditeur(s) : HAL CCSD
Résumé : To understand the effect of inherited lithospheric structures on the continental plates deformation process, we have developed a multi scale model that explicitly takes into account an anisotropic viscosity due to the Crystal Preferred Orientation (CPO) of olivine in the mantle by coupling a viscoplastic self-consistent simulation of the deformation at the polycrystalline aggregate to a 3D Finite Element code. Using this tool, we calculate the mechanical behavior of a continental lithosphere submitted to extension for various initial structures. The first set of experiments investigates the deformation of a plate with a homogeneous initial olivine CPO. Results show that the macroscopic anisotropy is strongly dependent on the initial orientation of the olivine CPO relative to the solicitation and to its evolution. The second set of experiments aims to analyze the deformation of a continental plate containing pre-existing lithospheric scale shear zones. These multi-domain models show that the olivine mechanical anisotropy may induce the reactivation of pre-existing lithospheric scale shear zones in a plate submitted to rifting. In both cases, the results shows that the macroscopic mechanic anisotropy induced by the evolution of olivine CPO in the upper mantle is a key parameter to understand the deformation of the continental plates and to explain the observed reactivation of inherited structure from past tectonics events
Afin de comprendre l'effet des structures préexistantes sur la déformation des plaques continentales, nous avons développé une méthode de modélisation mécanique multi-échelle utilisant une viscosité anisotrope induite par les Orientations Préférentielles du Réseau (OPR) des cristaux d'olivine présents dans le manteau. Cette méthode en couple le calcul viscoplastique autocohérent de la déformation d'un agrégat d'olivine à un code éléments finis 3D. Elle a été utilisée pour le calcul du comportement mécanique d'une plaque continentale soumise à une extension. Une première série d'expériences numériques sur l'extension de plaque lithosphérique présentant des OPR initiales d'olivine homogènes a permis de montrer que l'anisotropie mécanique macroscopique est fortement dépendante de l'orientation initiale de l'OPR. La seconde série de simulations analyse l'extension d'une plaque continentale présentant une zone présentant des OPR d'olivine héritées d'un événement tectonique précédant. Les résultats de ces calculs multi-domaines que l'anisotropie mécanique de l'olivine peut expliquer la réactivation des zones de cisaillement héritées lors du rifting. Les résultats obtenus dans les deux séries de modèles montrent que l'anisotropie mécanique macroscopique induite par l'évolution des OPR d'olivine dans le manteau supérieur est un paramètre clé pour la compréhension de la déformation des plaques continentales et pour expliquer la réactivation observée de structures tectoniques, tels que les grands décrochements, lors des épisodes tectoniques ultérieurs.
https://tel.archives-ouvertes.fr/tel-00369463

tel-00369463
https://tel.archives-ouvertes.fr/tel-00369463
https://tel.archives-ouvertes.fr/tel-00369463/document
https://tel.archives-ouvertes.fr/tel-00369463/file/KnollThese09.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The aim of this work is to propose viscosity approximation methods which amounts to selecting a particular fixed-point of a given nonexpansive self-mapping.
Journal of Mathematical Analysis and applications

hal-00776600
https://hal.univ-antilles.fr/hal-00776600
DOI : 10.1006/jmaa.1999.6615

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Objectives To investigate the association between priapism in men with sickle cell anemia (SCA) and hemorheological and hemolytical parameters. Materials and Methods Fifty-eight men with SCA (median age: 38 years) were included; 28 who had experienced priapism at least once during their life (priapism group) and 30 who never experienced this complication (control group). Twenty-two patients were treated with hydroxycarbamide, 11 in each group. All patients were at steady state at the time of inclusion. Hematological and biochemical parameters were obtained through routine procedures. The Laser-assisted Optical Rotational Cell Analyzer was used to measure red blood cell (RBC) deformability at 30 Pa (ektacytometry) and RBC aggregation properties (laser backscatter versus time). Blood viscosity was measured at a shear rate of 225 s(-1) using a cone/plate viscometer. A principal component analysis was performed on 4 hemolytic markers (i.e., lactate dehydrogenase (LDH), aspartate aminotransferase (ASAT), total bilirubin (BIL) levels and reticulocyte (RET) percentage) to calculate a hemolytic index. Results Compared to the control group, patients with priapism exhibited higher ASAT (p = 0.01), LDH (p = 0.03), RET (p = 0.03) levels and hemolytic indices (p = 0.02). Higher RBC aggregates strength (p = 0.01) and lower RBC deformability (p = 0.005) were observed in patients with priapism compared to controls. After removing the hydroxycarbamide-treated patients, RBC deformability (p = 0.01) and RBC aggregate strength (p = 0.03) were still different between the two groups, and patients with priapism exhibited significantly higher hemolytic indices (p = 0.01) than controls. Conclusion Our results confirm that priapism in SCA is associated with higher hemolytic rates and show for the first time that this complication is also associated with higher RBC aggregate strength and lower RBC deformability.
ISSN: 1932-6203

hal-01390971
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01390971
DOI : 10.1371/journal.pone.0154866
PUBMED : 27145183

Éditeur(s) : HAL CCSD IOS Press
Résumé : International audience
This document, supported by both the International Society for Clinical Hemorheology and the European Society for Clinical Hemorheology and Microcirculation, proposes new guidelines for hemorheological methods used in experimental and clinical studies. It is based on a similar document entitled: "Guidelines for measurement of blood viscosity and erythrocyte deformability" published in 1986 by the Expert Panel on Blood Rheology of the International Committee for Standardization in Hematology. Recent methods, techniques and instruments, as well as new approaches to interpretation of results, are added to these new guidelines; wide spread adoption should improve comparability between hemorheological laboratories and increase the reliability of rheological tests.
ISSN: 1386-0291

hal-00709840
https://hal.archives-ouvertes.fr/hal-00709840
https://hal.archives-ouvertes.fr/hal-00709840/document
https://hal.archives-ouvertes.fr/hal-00709840/file/New_Guidelines_accepted_1-4-2009.pdf

Éditeur(s) : HAL CCSD Yokohama Publishers
Résumé : International audience
ISSN: 1348-9151

hal-00780002
https://hal.univ-antilles.fr/hal-00780002

Éditeur(s) : HAL CCSD IOS Press
Résumé : International audience
Purpose: The aim of this study was to clarify whether exercising in a tropical climate induces blood rheology alterations despite ad libitum hydration. Methods: Hematological, biochemical and hemorheological changes were investigated in young healthy adults (N = 9 men, 20.7 ± 0.8 yrs) after a 10-km race in hot and humid conditions. Subjects' maximal aerobic abilities were tested using a maximal ramp exercise. Blood was sampled at rest (T R), at the end of the race (T Ex), and after 24 hours of recovery (T 24). Ad libitum hydra-tion was allowed during the race. Blood viscosity (b), red blood cell deformability (EI), aggregation (AI) and disaggregation shear rate (␥) were measured. Results: Hematocrit, hemoglobin and plasma concentration of chlorine, sodium and potassium did not change in response to exercise. No functional consequence was observed on RBC deformability since EI remained unchanged. Percentages of echinocytes, schizocytes and stomatocytes remained in the subclinical range at all times. AI, µ and ßb did not present change. Conclusion: Running exercise in tropical climate with ad libitum hydration does not alter the main rheological properties of blood.
ISSN: 1386-0291

hal-01163975
https://hal.univ-antilles.fr/hal-01163975
DOI : 10.3233/CH-2011-1388

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Continuous Global Positioning System (CGPS) position time series from eastern North America constrain the pattern and magnitude of regional crustal deformation. Initial analysis delineates consistent uplift patterns, as expected from glacial isostatic adjustment (GIA) predictions, but the associated horizontal deformation is not definitive, in part due to the short time periods for a significant number of the available stations. We employ an eigenpattern decomposition in order to define a unique, finite set of deformation patterns for this continuous GPS data. Similar in nature to the empirical orthogonal functions historically employed in the analysis of atmospheric and oceanographic phenomena, the method derives the eigenvalues and eigenstates from the diagonalization of the correlation matrix using a Karhunen-Loeve expansion (KLE). The KLE technique is used to identify the important modes in both time and space for the CGPS data, modes that potentially include signals such as horizontal and vertical GIA, tectonic strain, and seasonal effects. Here we filter both the vertical and horizontal velocity patterns on different spatiotemporal scales in order to study the potential geophysical sources, after the removal of correlated and random noise. The method is successful in disaggregating the linear vertical signal from more variable and less spatially correlated signals. The vertical and horizontal results are compared to the predictions of the ICE-3G GIA loading model with a number of plausible mantle viscosity profiles. The horizontal velocity analysis allows for qualitative differentiation between several potential GIA models and suggests that, with longer time series, this technique can be employed to remove correlated noise and improve estimates of crustal strain patterns and their sources.
ISSN: 0033-4553

hal-00795454
https://hal.archives-ouvertes.fr/hal-00795454
DOI : 10.1007/s00024-011-0420-1