Éditeur(s) : Caribbean Volunteer Expeditions Caribbean Volunteer Expeditions ( Corning, NY )

Droits : All rights reserved by the source institution.

Éditeur(s) : HAL CCSD American Geophysical Union
Résumé : International audience
Rheological properties of mantle minerals and rocks at temperatures (T) appropriate to much of Earth's lithosphere have remained poorly constrained, even though past experimental studies on olivine single crystals and polycrystalline aggregates have quantified the high-temperature creep mechanisms (T > 1200 degrees C). Consequently, we have performed deformation experiments on crystals of San Carlos olivine at lower temperatures, from 900 degrees to 1200 degrees C, in triaxial compression along the [101](c) direction. The experiments were carried out at a confining pressure of 300 MPa in a high-resolution gas-medium mechanical testing apparatus at differential stresses of 100 to 500 MPa. Several samples were deformed at constant displacement rate and others at constant load, in order to provide insight into possible effects of work-hardening. Under the deformation conditions investigated, little evidence of work-hardening was observed. The data follow a power-law dependence on stress, as in previous high-temperature deformation studies. The samples were, however, considerably weaker than predicted by the experimentally determined high-temperature constitutive equation for olivine crystals of this orientation from the study of Bai et al. (1991). The mechanical behavior correlates instead with the weaker of the two mechanisms (flow laws) that contribute to the high-temperature constitutive equation. Thus, our experiments demonstrate that published high-temperature constitutive equations overestimate the strength of lithospheric mantle and that the transition to low-temperature creep occurs at lower temperatures than previously inferred. Citation: Demouchy, S., S. E. Schneider, S. J. Mackwell, M. E. Zimmerman, and D. L. Kohlstedt (2009), Experimental deformation of olivine single crystals at lithospheric temperatures, Geophys. Res. Lett., 36, L04304, doi: 10.1029/2008GL036611.
ISSN: 0094-8276

hal-00420070
https://hal.archives-ouvertes.fr/hal-00420070
DOI : 10.1029/2008GL036611

Siècle(s) traité(s) : 17
Droits : Domaine public
Provenance : Archives territoriales de Guyane
Permalien : http://www.manioc.org/patrimon/GAD11008
GAD11008

Résumé : Extrait du Journal de physique du mois de mai 1788
Siècle(s) traité(s) : 18
Provenance : Ville de Bordeaux. Bibliothèque municipale
Permalien : http://www.manioc.org/patrimon/BBX19033
BBX19033

Éditeur(s) : Paris : Recueil Sirey
Résumé : 6e édition, entièrement revue et condensée par Maurice Besson. Introduction générale par René Maunier.
Siècle(s) traité(s) : 16
Droits : Domaine public
Provenance : Communauté d'agglomération de La Rochelle. Médiathèque Michel-Crépeau
Permalien : http://www.manioc.org/patrimon/MMC16029
MMC16029

Éditeur(s) : Paris : A. Challamel
Résumé : Revue mensuelle d'agronomie tropicale : juillet à décembre 1913
Siècle(s) traité(s) : 20
Droits : Domaine public
Provenance : Collectivité territoriale de Guyane. Bibliothèque Alexandre-Franconie
Permalien : http://www.manioc.org/patrimon/FRA11277
FRA11277

Extrait de : L'illustration, n°277, p. 119-121
Résumé : Article et photographies 4 p.
Siècle(s) traité(s) : 20
Droits : Domaine public
Provenance : ORkidé|Fonds privé Pierre Rostan
Permalien : http://www.manioc.org/patrimon/ORK12155
ORK12155

Éditeur(s) : Paris : Librairie Larousse
Siècle(s) traité(s) : 19
Droits : Domaine public
Provenance : Communauté d'agglomération de La Rochelle. Médiathèque Michel-Crépeau
Permalien : http://www.manioc.org/patrimon/MMC16023-2
MMC16023-2

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The Hedgehog (Hh) family of secreted proteins act as morphogens to control embryonic patterning and development in a variety of organ systems. Post-translational covalent attachment of cholesterol and palmitate to Hh proteins are critical for multimerization and long range signaling potency. However, the biological impact of lipid modifications on Hh ligand distribution and signal reception in humans remains unclear. In the present study, we report a unique case of autosomal recessive syndromic 46,XY Disorder of Sex Development (DSD) with testicular dysgenesis and chondrodysplasia resulting from a homozygous G287V missense mutation in the hedgehog acyl-transferase (HHAT) gene. This mutation occurred in the conserved membrane bound O-acyltransferase (MBOAT) domain and experimentally disrupted the ability of HHAT to palmitoylate Hh proteins such as DHH and SHH. Consistent with the patient phenotype, HHAT was found to be expressed in the somatic cells of both XX and XY gonads at the time of sex determination, and Hhat loss of function in mice recapitulates most of the testicular, skeletal, neuronal and growth defects observed in humans. In the developing testis, HHAT is not required for Sertoli cell commitment but plays a role in proper testis cord formation and the differentiation of fetal Leydig cells. Altogether, these results shed new light on the mechanisms of action of Hh proteins. Furthermore, they provide the first clinical evidence of the essential role played by lipid modification of Hh proteins in human testicular organogenesis and embryonic development.
ISSN: 1553-7390

hal-01063929
https://hal.archives-ouvertes.fr/hal-01063929
DOI : 10.1371/journal.pgen.1004340
PUBMED : 24784881

Éditeur(s) : Paris : Morizot
Résumé : Nouvelle édition
Il manque les tomes : 1:Histoire de la géographie 3:Asie(suite) 8:Europe(suite) et Table générale Chaque tome concernant des pays précis , ils sont indépendant les uns des autres
Description : Nouvelle édition continuée jusqu'à nos jours, d'après les documents scientifiques les plus récents, les derniers voyages et les dernières découvertes par V.-A. Malte-Brun fils,...

Droits : Domaine public
Provenance : Collectivité territoriale de Guyane. Bibliothèque Alexandre-Franconie
Permalien : http://www.manioc.org/patrimon/FRA11193
FRA11193

Éditeur(s) : Cayenne : Imprimerie du gouvernement
Résumé : Année 1916
Siècle(s) traité(s) : 20
Droits : Domaine public
Provenance : Collectivité territoriale de Guyane. Bibliothèque Alexandre-Franconie
Permalien : http://www.manioc.org/patrimon/FRA11243
FRA11243

Éditeur(s) : Paris : Morizot
Résumé : Nouvelle édition
Description : Nouvelle édition continuée jusqu'à nos jours, d'après les documents scientifiques les plus récents, les derniers voyages et les dernières découvertes par V.-A. Malte-Brun fils,...

Droits : Domaine public
Provenance : Collectivité territoriale de Guyane. Bibliothèque Alexandre-Franconie
Permalien : http://www.manioc.org/patrimon/FRA11196
FRA11196

Éditeur(s) : HAL CCSD Endocrine Society
Résumé : International audience
Sertoli cells (SCs), the only somatic cells within seminiferous tubules, associate intimately with developing germ cells. They not only provide physical and nutritional support but also secrete factors essential to the complex developmental processes of germ cell proliferation and differentiation. The SC transcriptome must therefore adapt rapidly during the different stages of spermatogenesis. We report comprehensive genome-wide expression profiles of pure populations of SCs isolated at 5 distinct stages of the first wave of mouse spermatogenesis, using RNA sequencing technology. We were able to reconstruct about 13 901 high-confidence, nonredundant coding and noncoding transcripts, characterized by complex alternative splicing patterns with more than 45% comprising novel isoforms of known genes. Interestingly, roughly one-fifth (2939) of these genes exhibited a dynamic expression profile reflecting the evolving role of SCs during the progression of spermatogenesis, with stage-specific expression of genes involved in biological processes such as cell cycle regulation, metabolism and energy production, retinoic acid synthesis, and blood-testis barrier biogenesis. Finally, regulatory network analysis identified the transcription factors endothelial PAS domain-containing protein 1 (EPAS1/Hif2α), aryl hydrocarbon receptor nuclear translocator (ARNT/Hif1β), and signal transducer and activator of transcription 1 (STAT1) as potential master regulators driving the SC transcriptional program. Our results highlight the plastic transcriptional landscape of SCs during the progression of spermatogenesis and provide valuable resources to better understand SC function and spermatogenesis and its related disorders, such as male infertility.
ISSN: 0888-8809

hal-01146846
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01146846
DOI : 10.1210/me.2014-1356
PUBMED : 25710594

Résumé : Publiée dans le cadre du premier Congrès international d'histoire coloniale à Paris
Siècle(s) traité(s) : 20
Droits : Domaine public
Provenance : Ville de Pointe-à-Pitre. Réseau des bibliothèques
Permalien : http://www.manioc.org/patrimon/PAP11103
PAP11103

Éditeur(s) : HAL CCSD Society for the Study of Reproduction
Résumé : International audience
The endonuclease DICER that processes micro-RNAs and small interfering RNAs is essential for normal spermatogenesis and male fertility. We previously showed that the deletion of Dicer1 gene in postnatal spermatogonia in mice using Ngn3 promoter-driven Cre expression caused severe defects in the morphogenesis of haploid spermatid to mature spermatozoon, including problems in cell polarization and nuclear elongation. In this study, we further analyzed the same mouse model and revealed that absence of functional DICER in differentiating male germ cells induces disorganization of the cell-cell junctions in the seminiferous epithelium. We detected discontinuous and irregular apical ectoplasmic specializations between elongating spermatids and Sertoli cells. The defective anchoring of spermatids to Sertoli cells caused a premature release of spermatids into the lumen. Our findings may help also explain the abnormal elongation process of remaining spermatids because these junctions and the correct positioning of germ cells in the epithelium are critically important for the progression of spermiogenesis. Interestingly, cell adhesion-related genes were generally upregulated in Dicer1 knockout germ cells. Claudin 5 ( Cldn5 ) was among the most upregulated genes and we show that the polarized localization of CLAUDIN5 in the apical ectoplasmic specializations was lost in Dicer1 knockout spermatids. Our results suggest that DICER-dependent pathways control the formation and organization of cell-cell junctions in the seminiferous epithelium via the regulation of cell adhesion-related genes
ISSN: 0006-3363

hal-01274239
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01274239
DOI : 10.1095/biolreprod.115.131938
PUBMED : 26510868

Éditeur(s) : Paris : Librairie Paul Ollendorff
Siècle(s) traité(s) : 18
Droits : Domaine public
Provenance : Collectivité territoriale de Guyane. Bibliothèque Alexandre-Franconie
Permalien : http://www.manioc.org/patrimon/FRA12065
FRA12065

Éditeur(s) : Paris : P. Ollendorf
Résumé : Publié d'après les manuscrits inédits
Deuxième édition
Siècle(s) traité(s) : 20
Droits : Domaine public
Provenance : Ville de Pointe-à-Pitre. Réseau des bibliothèques
Permalien : http://www.manioc.org/patrimon/PAP11021
PAP11021

Éditeur(s) : Paris : Morizot
Résumé : Nouvelle édition
Description : Nouvelle édition continuée jusqu'à nos jours, d'après les documents scientifiques les plus récents, les derniers voyages et les dernières découvertes par V.-A. Malte-Brun fils,...

Droits : Domaine public
Provenance : Collectivité territoriale de Guyane. Bibliothèque Alexandre-Franconie
Permalien : http://www.manioc.org/patrimon/FRA11197
FRA11197

Éditeur(s) : Paris : A. Picard et fils

Droits : Domaine public
Provenance : Université de Nantes. Service commun de la documentation
Permalien : http://www.manioc.org/patrimon/NAN13024
NAN13024

Éditeur(s) : Port-au-Prince, Haïti : Imprimerie La Presse
Siècle(s) traité(s) : 20
Provenance : Conseil départemental de la Guadeloupe. La Médiathèque Caraïbe
Permalien : http://www.manioc.org/patrimon/LAM18023
LAM18023