Éditeur(s) : HAL CCSD Ecological Society of America
Résumé : Tropical plant diversity is extraordinarily high at both local and regional scales. Many studies have demonstrated that natural enemies maintain local diversity via negative density dependence, but we know little about how natural enemies influence beta-diversity across habitats and/or regions. One way herbivores could influence plant beta-diversity is by driving allocation trade-offs that promote habitat specialization across resource gradients. We therefore predicted that increasing resource availability should be accompanied by increasing herbivory rates and decreasing plant allocation to defense. Second, relative abundances within plant lineages are predicted to reflect patterns of habitat specialization and allocation trade-offs. A phylogenetic context is vital not only to compare homologous plant traits (including defense strategies) across habitat types, but also to connect evolutionary trade-offs to patterns of species diversification in each phylogenetic lineage. We tested these predictions for trees in white-sand, clay terra firme, and seasonally flooded forests in Peru and French Guiana that represent the range of soil fertility, forest structure, and floristic compositions found throughout the Amazon region. We established 74 0.5-ha plots in these habitats and sampled all trees. Within 12 representative plots we marked newly expanding leaves of 394 saplings representing 68 species, including the most abundant species in each plot in addition to species from five focal lineages: Swartzia and Inga (Fabaceae), Protieae (Burseracaeae), Bombacoideae (Malvaceae), and Micropholis (Sapotaceae). We measured total leaf production rates for each sapling and calculated relative herbivory impact as the ratio between herbivory rate and leaf production rate. Herbivory rates averaged 2.1% per month, did not correlate with leaf production rate, and were similar across habitats. Relative herbivore impacts exceeded leaf production rates for most species. Leaf production rate averaged 2.8%, was significantly higher in seasonally flooded forests than the other two habitats, and exhibited significant correlations with specific leaf area. Species with high herbivory rates exhibited significantly lower relative abundances in terra firme forests. Overall, focal species within lineages present contrasting patterns regarding their herbivory rates and leaf production rate within habitats. These results highlight why a lineage-based approach is necessary when attempting to connect hypotheses regarding evolutionary trade-offs to community assembly patterns.
ISSN: 0012-9658

hal-01032418
https://hal.archives-ouvertes.fr/hal-01032418

Éditeur(s) : HAL CCSD Université des Antilles
Résumé : International audience
Ecotourism provides an original conceptual framework that enables approaches to development that are better able to provide a more equitable distribution of income, as well as better organized and thought through initiatives which are more likely to promote a holistic sustainable local development. With somewhat less negative impact than normal tourism, considerably less that mass tourism, ecotourism can encompass nature tourism, cultural tourism, scientific exploration, and even outdoor sports... A definition of ecotourism should take into account the following six points: 1/ nature and culture, 2/ the welfare of the host community, tourists acting responsibly, 3/ participation by the local community, 5 / sustainability , 6/ promotion of cultural exchanges.
L’écotourisme ouvre un cadre conceptuel original qui permet d’envisager des démarches renouvelées de développement à partir des revenus issus de consommations touristiques mieux réfléchies et organisées, susceptibles de soutenir des initiatives de développement local s’inscrivant dans un projet global de développement durable. Variante douce du tourisme, loin du tourisme de masse, le champ de l’écotourisme s’étend aux confins du tourisme de nature, du tourisme culturel et des pratiques scientifiques et sportives de plein air. Une définition de l’écotourisme peut être proposée à partir des six points suivants : 1/ nature et culture, 2/ le bien-être des sociétés hôtes, 3/ des touristes responsables, 4/ la participation des sociétés hôtes, 5/ la durabilité, 6/ l’art de la rencontre.
ISSN: 1779-0980

hal-01624739
https://hal.archives-ouvertes.fr/hal-01624739
DOI : 10.4000/etudescaribeennes.414

Éditeur(s) : Actes de colloque Ifremer n°28, 2000. ISBN-13 978-2-84433-047-5 ISBN-10 978-2-84433-047-5
Résumé : The international symposium "Tuna Fishing and Fish Aggregating Devices " , October 1999, in Martinique, takes stock of the exploitation of large pelagic fish around FADs, based on regional synthesis for the three oceans and the Mediterranean Sea. Main themes include technology, fishing methods, impact on resources, biology of fish aggregation, anthropology and economic aspects of FAD exploitation. The meeting will gather and disseminate results from recent and ongoing studies on FADs in the different oceans of the world, enhance collaboration between scientists and managers involved in the development of FADs, promote the emergence of scientific and technical research, form a network for cooperation and enhance communications between researchers in the different locations concerned.
Le colloque international « Pêche thonière et dispositifs de concentration de poissons» organisé en octobre 1999, en Martinique, permet de dresser un bilan, sous forme de synthèses régionales, de l'exploitation des grands poissons pélagiques à l'aide de DCP dans les trois océans et en Méditerranée. La technologie, les méthodes de pêche, l'impact sur les ressources, le comportement agrégatif des poissons et les aspects socio-économiques de l'utilisation des DCP sont les principaux thèmes développés. Ces travaux permettront d'assurer une diffusion large des résultats à l'échelle de l'océan mondial, de favoriser les échanges entre les scientifiques et les gestionnaires impliqués dans le développement des systèmes DCP, de promouvoir l'émergence de thèmes et projets de recherche scientifique et technologique, de mettre en oeuvre un réseau de communication et d'échanges entre les sites et les régions concernées.

Droits : 2000 Ifremer
http://archimer.ifremer.fr/doc/00042/15326/12646.pdf
http://archimer.ifremer.fr/doc/00042/15326/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Estrogen receptor alpha (ERα) is generally considered to be a good prognostic marker because almost 70% of ERα-positive tumors respond to anti-hormone therapies. Unfortunately, during cancer progression, mammary tumors can escape from estrogen control, resulting in resistance to treatment. In this study, we demonstrate that activation of the actin/megakaryoblastic leukemia 1 (MKL1) signaling pathway promotes the hormonal escape of estrogen-sensitive breast cancer cell lines. The actin/MKL1 signaling pathway is silenced in differentiated ERα-positive breast cancer MCF-7 and T47D cell lines and active in ERα-negative HMT-3522 T4-2 and MDA-MB-231 breast cancer cells, which have undergone epithelial-mesenchymal transition. We showed that MKL1 activation in MCF-7 cells, either by modulating actin dynamics or using MKL1 mutants, down-regulates ERα expression and abolishes E2-dependent cell growth. Interestingly, the constitutively active form of MKL1 represses PR and HER2 expression in these cells and increases the expression of HB-EGF, TGFβ, and amphiregulin growth factors in an E2-independent manner. The resulting expression profile (ER-, PR-, HER2-) typically corresponds to the triple-negative breast cancer expression profile.
ISSN: 0303-7207

hal-01061363
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01061363
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01061363/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01061363/file/Activationsur the_MKL1actin_Kerdivel_et_al._text_Figures.pdf
DOI : 10.1016/j.mce.2014.03.009

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Understanding how communities respond to natural disturbances is fundamental to assess the mechanisms of ecosystem resistance and resilience. However, ecosystem responses to natural disturbances are rarely monitored both through space and time, while the factors promoting ecosystem stability act at various temporal and spatial scales. Hence, assessing both the spatial and temporal variations in species composition is important to comprehensively explore the effects of natural disturbances. Here, we suggest a framework to better scrutinize the mechanisms underlying community responses to disturbances through both time and space. Our analytical approach is based on beta diversity decomposition into two components, replacement and biomass difference. We illustrate this approach using a 9-year monitoring of coral reef fish communities off Moorea Island (French Polynesia), which encompassed two severe natural disturbances: a crown-of-thorns starfish outbreak and a hurricane. These disturbances triggered a fast logistic decline in coral cover, which suffered a 90% decrease on all reefs. However, we found that the coral reef fish composition remained largely stable through time and space whereas compensatory changes in bio-mass among species were responsible for most of the temporal fluctuations, as outlined by the overall high contribution of the replacement component to total beta diversity. This suggests that, despite the severity of the two disturbances, fish communities exhibited high resistance and the ability to reorganize their compositions to maintain the same level of total community biomass as before the disturbances. We further investigated the spatial congruence of this pattern and showed that temporal dynamics involved different species across sites; yet, herbivores controlling the proliferation of algae that compete with coral communities were consistently favored. These results suggest that compensatory changes in bio-mass among species and spatial heterogeneity in species responses can provide further
ISSN: 1932-6203

hal-01212344
https://hal-univ-perp.archives-ouvertes.fr/hal-01212344
https://hal-univ-perp.archives-ouvertes.fr/hal-01212344/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01212344/file/journal.pone.0138696.pdf
DOI : 10.1371/journal.pone.0138696

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This work combines structural and geochronological data to improve our understanding of the mechanical behaviour of continental crust involving large amount of magma or partially melted material in an abnormally hot collisional belt. We performed a magnetic and geochronological (U/Pb) study on a huge tonalitic batholith from the Neoproterozoic Araçuaí belt of East Brazil to determine the strain distribution through space and time. Anisotropy of magnetic susceptibility, combined with rock magnetism investigations, supports that the magnetic fabric is a good proxy of the structural fabric. Field measurements together with the magnetic fabrics highlight the presence in the batholith of four domains characterized by contrasted magmatic flow patterns. The western part is characterized by a gently dipping, orogen-parallel (∼NS) magmatic foliation that bears down-dip lineations, in agreement with westward thrusting onto the São Francisco craton. Eastward, the magmatic foliation progressively turns sub-vertical with a lineation that flips from sub-horizontal to sub-vertical over short distances. This latter domain involves an elongated corridor in which the magmatic foliation is sub-horizontal and bears an orogen-parallel lineation. Finally the fourth, narrow domain displays sub-horizontal lineations on a sub-vertical magmatic foliation oblique (∼N150°E) to the trend of the belt. U/Pb dating of zircons from the various domains revealed homogeneity in age for all samples. This, together with the lack of solid-state deformation suggests that: 1) the whole batholith emplaced during a magmatic event at ∼580 Ma, 2) the deformation occurred before complete solidification, and 3) the various fabrics are roughly contemporaneous. The complex structural pattern mapped in the studied tonalitic batholith suggests a 3D deformation of a slowly cooling, large magmatic body and its country rock. We suggest that the development of the observed 3D flow field was promoted by the low viscosity of the middle crust that turned gravitational force as an active tectonic force combining with the East-West convergence between the São Francisco and Congo cratons.
ISSN: 0191-8141

hal-00745696
https://hal.archives-ouvertes.fr/hal-00745696
DOI : 10.1016/j.jsg.2012.02.015

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
STUDY QUESTION: Can protein biomarkers of the male genital tract be identified in human seminal plasma? SUMMARY ANSWER: We identified potential biomarkers for each of the organs participating in the secretions of the human seminal plasma. WHAT IS KNOWN ALREADY: The seminal plasma fulfills critical functions for fertility by providing spermatozoa with a protective milieu, promoting their final maturation and modulating the immune responsiveness of the female reproductive tract. It is also considered to be a promising source of biomarkers of male infertility and/or pathologies of the male genital tract. STUDY DESIGN, SIZE, DURATION: This study combines proteomic analyses of normal seminal plasma together with transcriptomic gene expression profiling of human healthy tissues. MATERIALS, SETTING, METHODS: Non-liquefied seminal plasma proteins from a healthy donor were prefractionated using two sequential Proteominer™ libraries. Eight subproteome fractions were collected, trypsin digested and subjected to three successive mass spectrometry analyses for peptide characterization. The list of identified proteins was compared with and merged with other available data sets of the human seminal plasma proteome. The expression of corresponding genes was then investigated using tissue transcriptome profiles to determine where, along the male reproductive tract, these proteins were produced. Finally, tissue specificity of a selected subset of biomarker candidates was validated on human tissues. MAIN RESULTS AND THE ROLE OF CHANCE: We first performed a proteomic analysis of the human seminal plasma and identified 699 proteins. By comparing our protein list with other previous proteomic data sets, we found that 2545 unique proteins have been described so far in the human seminal plasma. We then profiled their expression at the gene level and identified 83 testis, 42 epididymis, 7 seminal vesicle and 17 prostate candidate protein markers. For a subset of testis-specific candidates, i.e. TKTL1, LDHC and PGK2, we further validated their germ cell expression and demonstrated that such markers could distinguish between semen from fertile and infertile men. LIMITATIONS, REASONS FOR CAUTION: While some of the markers we identified are well-known tissue-specific products, further dedicated studies to validate the biomarker status of new candidates will be required. Additionally, whether or not the abundance of these proteins is indeed decreased in some specific pathological situations remains to be determined. WIDER IMPLICATIONS OF THE FINDINGS: Using an integrative genomics approach, we identified biomarker candidates for each of the organs participating in the seminal plasma production. In this study, we essentially focused on germ cell markers and their potential application for the diagnosis of male infertility. Other types of markers also deserve a focused attention given their potential predictive value for various reproductive disorders, notably for prostate cancers. STUDY FUNDING/COMPETING INTEREST(S): This work was supported by the Proteomics Core Facility at Biogenouest and was funded by Conseil Régional de Bretagne, IBiSA and Agence de la Biomédecine grants. The authors declare that there exists a competing financial interest in this work that is related to a patent application on the use of identified germ cell-specific proteins in an antibody-based assay (Fertichip™) to predict the successful testicular biopsy outcomes in human non-obstructive azoospermia.
ISSN: 0268-1161

inserm-00814146
http://www.hal.inserm.fr/inserm-00814146
DOI : 10.1093/humrep/des360
PUBMED : 23024119

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Rapid cold hardening (RCH) is a form of thermal acclimation that allows ectotherms to fine-tune their physiological state to match rapid changes in thermal environment. Despite progress in recent years, there is still a considerable uncertainty regarding the physiological basis of RCH in insects. Here we investigated the physiological response of adult Drosophila melanogaster to a gradual reduction of temperature from 25 to 0°C followed by 1h at 0°C. As expected, this RCH treatment promoted cold tolerance, and so we hypothesized that this change could be detected at the proteomic level. Using 2D-DIGE, we found that only a few proteins significantly changed in abundance, and of these, we identified a set of four proteins of particular interest. These were identified as two different variants of glycogen phosphorylase (GlyP) of which three spots were up-regulated and another was down regulated. In subsequent experiments, we quantified upstream events by measuring the GlyP mRNA amount, but we found no marked effect of RCH. We also examined downstream events by measuring GlyP activity and the level of free sugars. We found no effect of RCH on GlyP activity. On the other hand, screening of whole animal sugar contents revealed a small increase in glucose levels following RCH while trehalose content was unaltered. This study highlights a complex regulation of GlyP in relation to RCH where we found associations between the cold tolerance, the protein abundance and the metabolite concentrations but no changes in mRNA expression and enzyme activity. These data stress the necessity of combining the hypothesis-generating power of an 'Omics' approach with subsequent targeted validations across several levels of the biological organization. We discuss reasons why different biological linked levels do not necessarily change stoichiometrically.
ISSN: 0022-1910

hal-00991032
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00991032
DOI : 10.1016/j.jinsphys.2014.01.009
PUBMED : 24508557

Résumé : Chapters in Volume 1: - Law of the sea and international straits - Trends in the French merchant fleet - International shipping - Safety and rescue at sea, the case of yachting - Marine research and economic development - The respective roles played at sea by the state and local authorities - Social trends in populations linked to the sea: commercial seafarers - Future perspectives for marine leisure activities - French ports, outlook for the year 2000 Chapters in Volume 2: - European organisation in terms of seafood - The role of the sea in the development of the DOM/TOM (French overseas départements and territories) - France's international policy and naval and maritime resources - Naval strategies of the major powers - Europe's security in the Mediterranean, the example of the Balkans - Nuclear-weapon-free areas and peace zones at sea - France and geopolitical balances in the South Pacific - The North-west of the Indian Ocean and the world energy supply
Rapports des dix-sept groupes de séminaires de la promotion "Liberté, égalité, fraternité" de l'Ecole nationale d'administration, février à juillet 1988: Chapitres du Tome1: - Le droit de la mer et les détroits internationaux - L'évolution de la flotte de commerce française - Les transports maritimes internationaux - Sécurité et sauvetage en mer, le cas de la plaisance - Recherche en mer et développement économique - Les rôles respectifs de l'État et des collectivités locales en mer - L'évolution sociale des populations attachées à la mer : les marins de commerce - Les perspectives d'avenir des loisirs de la mer - Les ports français, perspectives pour l'an 2000 Chapitres du Tome2: - Organisation européenne en matière de produit de la mer - Le rôle de la mer dans le développement des DOM/TOM - La politique internationale de la France et les moyens navals et maritimes - Les stratégies navales des grandes puissances - La sécurité de l'Europe en Méditerranée, l'exemple des Balkans - Les zones exemptes d'armes nucléaires et les zones de paix en mer - La France et les équilibres géopolitiques dans le Pacifique Sud - Le Nord-Ouest de l'océan Indien et l'approvisionnement énergétique mondial

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1988/rapport-1027.pdf
http://archimer.ifremer.fr/doc/1988/sup-1027.pdf
http://archimer.ifremer.fr/doc/00000/1027/

Éditeur(s) : Amer Geophysical Union
Résumé : On November 21, 2004, a magnitude 6.3 earthquake occurred offshore, 10 km south of Les Saintes archipelago in Guadeloupe (French West Indies). There were more than 30000 aftershocks recorded in the following two years, most of them at shallow depth near the islands of the archipelago. The main shock and its main aftershock of February 14, 2005 (M-w = 5.8) ruptured a NE-dipping normal fault (Roseau fault), mapped and identified as active from high-resolution bathymetric data a few years before. This fault belongs to an arc-parallel en echelon fault system that follows the inner edge of the northern part of the Lesser Antilles arc, accommodating the sinistral component of oblique convergence between the North American and Caribbean plates. The distribution of aftershocks and damage (destruction and landslides) are consistent with the main fault plane location and attitude. The slip model of the main shock, obtained by inverting jointly global broadband and local strong motion records, is characterized by two main slip zones located 5 to 10 km to the SE and NW of the hypocenter. The main shock is shown to have increased the Coulomb stress at the tips of the ruptured plane by more than 4 bars where most of the aftershocks occurred, implying that failures on fault system were mainly promoted by static stress changes. The earthquake also had an effect on volcanic activity since the Boiling Lake in Dominica drained twice, probably as a result of the extensional strain induced by the earthquake and its main aftershock.
Journal Of Geophysical Research-solid Earth (0148-0227) (Amer Geophysical Union), 2011-10 , Vol. 116 , N. B10301 , P. 1-25

Droits : Copyright 2011 by the American Geophysical Union.
http://archimer.ifremer.fr/doc/00200/31099/29511.pdf
DOI:10.1029/2011JB008310
http://archimer.ifremer.fr/doc/00200/31099/

Éditeur(s) : Actes du colloque, April 28-30 1997
Résumé : Due to favourable environmental conditions and political will, marine fish farming has developed recently around the Mediterranean. The Mediterranean area is characterised by a large number of islands which are extremely diversified from geographical, political or socioeconomic point of views. As a matter of fact, it turns out that almost a third of the Mediterranean fish farming production comes from these islands which have proven to offer good conditions for the development of that new activity. The reasons why somany enterprises have been established on islands are very diverse. Taking advantage of good environmental conditions is the most common motivation, since islands are usually less submitted to constraints due to town extension, industry development or intensive agriculture. Moreover, as far as European Union countries are concerned, incentive policy towards ultraperipheral or late development regions has made it possible to attribute specific subsidies to islands for aquaculture in the aim of more employment and wealth. Like any other economic activity, aquaculture has to face some specific constraints due to the insular context. Transport to and from the islands is more expensive and less regular, which has a negative impact on the price competitiveness of the insular products. Local markets are often too small to make it possible for the enterprises to develop first at a domestic level and to take advantage of economies of scale. Thanks to their positive and attractive world-wide image, Mediterranean islands could promote the quality of their products on the basis of geographical origin, of quality of the environment or of specific production processes. Information networks implementation and marketing approach in terms of image are challenges Mediterranean islands have to take up in order to supply the large European seafood market with quality products. [NOT CONTROLLED OCR]
Grâce à de bonnes conditions de milieu et à une volonté politique affirmée, l'élevage des poissons marins s'est développé récemment dans la Méditerranée. Le bassin méditerranéen possède un très grand nombre d'îles qui sont très diverses de par leur caractéristiques géographiques, politiques ou socio-économiques. Près du tiers de la production de poissons marins d'élevage des pays méditerranéens est réalisée dans des îles. Les raisons qui ont incité tant d'entreprises à s'établir sur des îles sont diverses. La motivation principale avancée par les promoteurs de l'aquaculture insulaire méditerranéenne est la qualité de l'environnement des îles et la disponibilité en sites, justifiée par le fait que les îles sont moins soumises à certaines contraintes comme l'extension des villes, le développement de zones industrielles ou l'intensification de l'agriculture. La politique d'aide envers les régions ultra-périphériques ou en retard de développement a permis d'attribuer des subventions spécifiques aux îles pour développer l'aquaculture dans un objectif de création de richesse et d'emploi. Comme toute autre activité économique dans les îles, l'aquaculture doit faire face à des contraintes directement liées à l'insularité. Le transport est plus coûteux et moins régulier, ce qui a un effet négatif sur la compétitivité prix des produits. Les marchés locaux sont souvent trop petits pour permettre aux entreprises de se développer d'abord en interne et de profiter d'économies d'échelle. Une réponse possible à cette contrainte de concurrence internationale pourrait être la promotion des produits sur la base de l'origine géographique,de la qualité de l'environnement ou de procédés de production spécifiques afin de valoriser l'image très positive et la notoriété de ces îles dans le monde entier. Les réseaux dédiés à l'information, à la recherche et au transfert technologique sont des outils nécessaires pour compenser les contraintes dues à la petite taille et à l'isolement dans le but de fournir le vaste marché européen en produits de la mer de qualité. [OCR NON CONTRÔLE]

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1997/acte-4010.pdf
http://archimer.ifremer.fr/doc/00000/4010/

Résumé : The goal of this study was to provide economic data to align Ifremer's research programme with the global socio-economic context, which is the crux of this work. Although the economies of the French Overseas Departments and Territories are poorly understood in mainland France, a brief macroeconomic analysis shows that they have the following main features: steady, but unbalanced growth, as indicated by high unemployment rates and low trade indices, and an overdeveloped services sector. This situation can be explained by an economic growth regime specific to the French overseas regions. It is based on, for the most part, public subsidies, a voluntary strategy promoted by the public authorities to raise the standards of living in the overseas regions.
L'objet de cette étude est de fournir des éléments économiques qui permettent de mettre en parallèle la démarche de programmation de recherche de l'IFREMER et le contexte socio-économique d'ensemble dans lequel cette recherche s'insère. Si l'économie des DOM-TOM reste méconnue en métropole, une analyse macroéconomique rapide montre bien quelles en sont les caractéristiques principales : une croissance soutenue mais très déséquilibrée comme l'attestent un taux de chômage élevé et un taux de couverture des importations dérisoire, l'existence d'un secteur tertiaire qualifié parfois d'"hypertrophié"... Cette situation s'explique par un mode de croissance spécifique à l'outre-mer français. Il repose pour une large part sur l'intervention financière publique, qui elle-même découle de la volonté exprimée par les pouvoirs publics de promouvoir un rattrapage rapide des niveaux de vie ultramarins. [OCR NON CONTRÔLE]

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1991/rapport-4094.pdf
http://archimer.ifremer.fr/doc/00000/4094/

Éditeur(s) : HAL CCSD
Résumé : International audience
Cumulative human impacts have led to the degradation of marine ecosystems and thedecline of biodiversity in the European and contiguous seas. Effective conservationmeasures are urgently needed to reverse these trends. Conservation must entail societalchoices, underpinned by human values and worldviews that differ between the countriesbordering these seas. Social, economic and political heterogeneity adds to the challenge ofbalancing conservation with sustainable use of the seas. Comprehensive macro-regionalcoordination is needed to ensure effective conservation of marine ecosystems andbiodiversity of this region. Under the European Union Horizon 2020 framework programme,the MarCons COST action aims to promote collaborative research to support marinemanagement, conservation planning and policy development. This will be achieved bydeveloping novel methods and tools to close knowledge gaps and advance marineconservation science. This action will provide support for the development of macro-regional and national policies through six key actions: to develop tools to analysecumulative human impacts; to identify critical scientific and technical gaps in conservationefforts; to improve the resilience of the marine environment to global change and biologicalinvasions; to develop frameworks for integrated conservation planning across terrestrial,freshwater, and marine environments; to coordinate marine conservation policy acrossnational boundaries; and to identify effective governance approaches for marine protectedarea management. Achieving the objectives of these actions will facilitate the integration ofmarine conservation policy into macro-regional maritime spatial planning agendas for theEuropean and contiguous seas, thereby offsetting the loss of biodiversity and ecosystemservices in this region.
Research Ideas and Outcomes

hal-01474085
https://hal-univ-perp.archives-ouvertes.fr/hal-01474085
https://hal-univ-perp.archives-ouvertes.fr/hal-01474085/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01474085/file/RIO_article_11884.pdf
DOI : 10.3897/rio.3.e11884

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Les « printemps » arabo-africains se suivent et ne se ressemblent pas, aux  « printemps » doux et pacifiques succèdent des « printemps » chauds et sanguinaires. Un « printemps » en chasse un autre, mais le bilan est mitigé, l’avenir encore incertain et les acquis réversibles. Indéniablement, ils n’ont pas encore dit leur dernier mot. De nouvelles raisons de préoccupations voient le jour, de nature différente ; elles ont pour nom : instabilité, intolérance, chaos, paralysie de l’État et ses institutions, menace qui plane sur le droit des femmes, des minorités de tous ordres, sur la liberté de conscience et le droit à la différence. Mais aussi de nouvelles raisons d’espérer des lendemains meilleurs.L'Afrique n’en est pas à un « printemps » près, mais les retombées sont toujours restées en deçà des attentes. La mise en place laborieuse d'un système panafricain des droits de l’homme et des peuples fut saluée, à juste titre, comme un évènement majeur et un « printemps » avant  la  lettre.L'article retrace toutes les étapes et péripéties de cette mise en place, le contexte, les tenants  et  les aboutissants de l'élaboration de la Charte africaine des droits de l'homme et des peuples qui en constitue le substratum. Il met en exergue ses spécificités, ses originalités, les mécanismes prévus et les organes érigés (Commission et Cour Africaine des Droits de l'Homme et des Peuples) pour assurer l'application et la promotion des  droits de l'homme et des peuples. À beaucoup d’égards, la Charte innove courageusement et originalement par  rapport à ses illustres devancières.Dans son intitulé d'abord : il s'agit d'une Charte et non d’une Déclaration. Ensuite, les droits de l’homme sont couplés aux droits des peuples et hissés au même niveau d'importance et d'impérativité, sinon plus. Enfin, la Charte ne reconnait pas seulement des droits mais elle édicte des devoirs (envers la famille, la communauté, l'État, l'Afrique, l’environnement, etc.) et fait de l'accomplissement de ceux-ci une condition de la jouissance de ceux-là. Deux décennies de recul et seulement 12 affaires traitées (sur seulement 24 qui lui sont parvenus), on peut dire que cette dernière est loin d'avoir atteint sa vitesse de croisière et mérité tant d'espoir placé en elle. De là à jeter le bébé avec l'eau du  bain, occulter tous les bienfaits d'un système qui est loin d'avoir démérité, il n'y a qu'un pas que ne franchirons guère.
The Arab-African springs follow one after the other but are not alike, soft and peaceful springs are succeeded by hot and bloodthirsty springs. One spring expels another one, but the situation s balance sheet is mixed, the future is still uncertain and the experiences are reversible. Undeniably, they didn't say their last word. New reasons of preoccupation are born, made of different nature : they are named : instability, intolerance, chaos, paralysis of the state and its institutions, threat to the women rights, minorities of all kinds, the conscience freedom and the rights to difference ; but also new reasons to hope for a better tomorrow. Africa is not at its last "spring" but the rewards remained always below expectations.The laborious Implementation of a Pan-African system of human rights and peoples was hailed, deservedly, as a major event and a "spring" far ahead of its time. The article in attached outlines all the steps and vicissitudes of this implementation rerelease the context, the end and results of the elaboration of human and people’s rights African charter which constitutes the substratum. It highlights its specificities, its originalities, the planed mechanisms and high instruments (Commission and the African Court of Human and Peoples' Rights) to ensure the application and the promotion of human and people’s rights.In many respects, the Charter innovates bravely and originally compared to its illustrious predecessors.At first in its title: it is matter of a charter and not a declaration. Then, human rights are closely connected to the people’s rights and hoisted at the same level of importance and imperativeness or more. Finally, the Charter does not only recognizes rights but it promulgates duties (to family, community, the state, Africa, the environment, etc.) and makes of the fulfillment of these a condition of enjoyment of those. Two decades backout, and only 12 cases treated (from only 24 have reached) later, in front of the Court, we can say that it is far from having reached its cruising speed and deserved so much hope placed in it.From there to throw the baby out with the bath water, hide all the benefits of a system which is far from being unworthy, there is only one step which shall exceed hardly.
Afrique

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.6735
http://journals.openedition.org/etudescaribeennes/6735

Éditeur(s) : Physiomar 08, Book of abstracts - Brest, France - 1-4 September, 2008
Résumé : This second mollusc physiology meeting has being organized jointly by LEMAR (IUEM: European Institute for Marine Studies) and LPI (Ifremer: French Institute for the Exploitation of the Sea), as both laboratories conduct research in this field. Physiomar 08 followed the very successful workshop 'Physiological aspects of reproduction and nutrition in marine mollusks' held in La Paz (Mexico) in November 2006 under the guidance of Maria Concepcion Lora Vilchis and Elena Palacios Metchenov from CIBNOR. This year's meeting has focus on Reproduction, Growth, Nutrition and Genetics and genomics of marine molluscs, and included a specific session on the effects of climate change on mollusc physiology: Global change. This conference has served as a forum for the communication of recent advances in all aspects of the physiology in molluscs. Researchers, students, stakeholders and mollusc farmers have had the opportunity to communicate personally in a friendly environment with leaders in the field. This meeting aimed to provide a vehicle for continuing exchanges, cooperation, and collaboration in the field of the physiology of marine molluscs to better understand their adaptation ability in a changing environment, their ecological significance, and to promote their sustainable culture.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/2008/acte-4600.pdf
http://archimer.ifremer.fr/doc/00000/4600/

Éditeur(s) : Elsevier Science Bv
Résumé : On the Mediterranean continental shelves the post-glacial transgressive succession is a complex picture composed by seaward progradations, related to sea level stillstands and/or increased sediment supply to the coasts, and minor flooding surfaces, associated to phases of enhanced rates of sea level rise. Among Late Pleistocene examples, major mid-shelf progradations have been related to the short-term climatic reversal of the Younger Dryas event, a period during which the combination of increased sediment supply from rivers and reduced rates of sea level rise promoted the formation of progradations up to tens-meter thick. While the documentation of coastal and subaqueous progradations recording the Younger Dryas interval are widely reported in the literature, the model of compound progradation within transgressive deposits is not proposed so far. Here we present the documentation of a deltaic system where both delta front sands and related fine-grained subaqueous progradations (prodeltaic to shallow marine) have been preserved. The Paleo Gargano Compound Delta (PGCD) formed offshore the modern Gargano Promontory (southern Adriatic Sea), and is composed by a coastal coarse-grained delta of reduced thickness and a muddy subaqueous clinoform, up to 30 meters thick. The PGCD, probably the first worldwide documentation of a compound delta within the transgressive record, provides the opportunity to investigate the processes controlling the formation of a compound delta system during an overall sea level rise and the factors that allowed its preservation. The finding of the PGCD provides the opportunity of a comparison with modern worldwide compound systems.
Marine Geology (0025-3227) (Elsevier Science Bv), 2015-04 , Vol. 362 , P. 43-59

Droits : 2015 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/00250/36158/34714.pdf
DOI:10.1016/j.margeo.2015.01.010
http://archimer.ifremer.fr/doc/00250/36158/

Éditeur(s) : Elsevier
Résumé : Evidence has accumulated that climate variability influences the state and functioning of marine ecosystems. At the same time increasing pressure from exploitation and other human activities has been shown to impact exploited and non-exploited species and potentially modify ecosystem structure. There has been a tendency among marine scientists to pose the question as a dichotomy, i.e., whether (1) "natural" climate variability or (2) fishery exploitation bears the primary responsibility for population declines in fish populations and the associated ecosystem changes. However, effects of both climate and exploitation are probably substantially involved in most cases. More importantly, climate and exploitation interact in their effects, such that climate may cause failure in a fishery management scheme but that fishery exploitation may also disrupt the ability of a resource population to withstand, or adjust to, climate changes. Here, we review how exploitation, by altering the structure of populations and ecosystems, can modify their ability to respond to climate. The demographic effects of fishing (removal of large-old individuals) can have substantial consequences on the capacity of populations to buffer climate variability through various pathways (direct demographic effects, effects on migration, parental effects). In a similar way, selection of population sub-units within metapopulations may also lead to a reduction in the capacity of populations to withstand climate variability and change. At the ecosystem level, reduced complexity by elimination of species, such as might occur by fishing, may be destabilizing and could lead to reduced resilience to perturbations. Differential exploitation of marine resources could also promote increased turnover rates in marine ecosystems, which would exacerbate the effects of environmental changes. Overall (and despite the specificities of local situations) reduction in marine diversity at the individual, population and ecosystem levels will likely lead to a reduction in the resilience and an increase in the response of populations and ecosystems to future climate variability and change. Future management schemes will have to consider the structure and functioning of populations and ecosystems in a wider sense in order to maximise the ability of marine fauna to adapt to future climates. (C) 2009 Elsevier B.V. All rights reserved.
Journal of Marine Systems (0924-7963) (Elsevier), 2010-02 , Vol. 79 , N. 3-4 , P. 403-417

Droits : 2009 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/2010/publication-7384.pdf
DOI:10.1016/j.jmarsys.2008.12.018
http://archimer.ifremer.fr/doc/00000/7384/

Éditeur(s) : Elsevier Sci Ltd
Résumé : The reduction of by-catch mortality is an objective of the ecosystem approach to fisheries and a request made by consumers. Elasmobranchs, an important component of the French tropical tuna purse seine fishery by-catch, are currently thrown back into the sea. Fishers interact with various types of elasmobranchs that range widely in size, weight and shape, and could pose various degrees of danger to the crew. A diversity of discarding practices within the fleet were reported, some practices were considered suitable, others needed to be adapted and improved and others simply had to be banned. The majority of the crews were likely to improve their handling practices if they were presented with practical suggestions that were quick and easy. Combining scientific observations and empirical knowledge from skippers and crew, a manual, providing appropriate handling practices to ensure crew safety and increase the odds of survival for released animals has been developed and disseminated. Bringing these good practices onto the decks of fishing vessels should contribute to the reduction of the fishing mortality of some vulnerable species. It would be positively viewed by consumers as an act that reduces fishing's footprint on the environment and promoting animal welfare which would improve the image of fishing industry. Mitigation research is by definition an iterative process and different complementary methods must be carried out at different levels of the fishing process to significantly reduce the mortality of the by-catch.
Marine Policy (0308-597X) (Elsevier Sci Ltd), 2014-02 , Vol. 44 , P. 312-320

Droits : 2013 Elsevier Ltd. All rights reserved.
http://archimer.ifremer.fr/doc/00159/27008/28367.pdf
DOI:10.1016/j.marpol.2013.09.025
http://archimer.ifremer.fr/doc/00159/27008/

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
Cancer cells display alterations in many cellular processes. One core hallmark of cancer is the Warburg effect which is a glycolytic reprogramming that allows cells to survive and proliferate. Although the contributions of environmental contaminants to cancer development are widely accepted, the underlying mechanisms have to be clarified. Benzo[a]pyrene (B[a]P), the prototype of polycyclic aromatic hydrocarbons, exhibits genotoxic and carcinogenic effects, and it is a human carcinogen according to the International Agency for Research on Cancer. In addition to triggering apoptotic signals, B[a]P may induce survival signals, both of which are likely to be involved in cancer promotion. We previously suggested that B[a]P-induced mitochondrial dysfunctions, especially membrane hyperpolarization, might trigger cell survival signaling in rat hepatic epithelial F258 cells. Here, we further characterized these dysfunctions by focusing on energy metabolism. We found that B[a]P promoted a metabolic reprogramming. Cell respiration decreased and lactate production increased. These changes were associated with alterations in the tricarboxylic acid cycle which likely involve a dysfunction of the mitochondrial complex II. The glycolytic shift relied on activation of the Na+/H+ exchanger 1 (NHE1) and appeared to be a key feature in B[a]P-induced cell survival related to changes in cell phenotype (epithelial-to-mesenchymal transition and cell migration).
ISSN: 2045-2322

Droits : http://creativecommons.org/licenses/by/
hal-01359569
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01359569
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01359569/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01359569/file/The%20environmental%20carcinogen-CCBY%20%281%29.pdf
DOI : 10.1038/srep30776

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Au cours des vingt dernières années, l'industrie des croisières au Mexique a apporté des changements importants qui découlent des tendances mondiales actuelles, d'un meilleur positionnement sur le marché, pour l'adoption généralisée de politiques nationales de promotion du tourisme croisière et pour la réforme radicale du système portuaire national qui a permis l'entrée de la participation privée dans les investissements des infrastructures, de gestion et d'exploitation des ports. Dans ce contexte, on a redéfini l´organisation spatiale du tourisme de croisière avec de nouveaux ports d´arrivée, des itinéraires variés à partir de différents ports d´origine et d’escales plaçant le Mexique en tête des destinations mondiales de l’industrie des croisières. Ainsi, l'objectif de cet article est d'examiner les conditions qui ont conduit à la dynamique spatio-temporelle du tourisme de croisière dans le pays à travers un examen critique de la nouvelle géographie régionale du tourisme de croisière au Mexique.
The cruise industry in Mexico has had significant changes stemming from current global trends during the last two decades. This has been due to its favorable and strategic geographical position in the market, its warm climate and proximity to the United States. Hence there has been a major relevance towards adopting national tourism policies as well as reforming the national port system allowing the entrance of private investment infrastructure, cruise terminal management and operation. The spatial organization of cruise tourism destination ports in Mexico has been redefined in this context. That is to say, there are new home ports, new routes and ports of call that have placed the country as a world’s leading destination for cruise ship arrivals. Therefore, the aim of this paper is to examine the conditions which have led the spatio-temporal dynamics into a critical review of the new regional geography of cruise tourism in Mexico.
En las dos últimas décadas el sector de los cruceros turísticos en México ha presentado profundos cambios, derivados de las tendencias globales, de un mayor aprovechamiento de su favorable condición geográfica dentro del mercado, por una mayor incorporación de la actividad en las políticas turísticas nacionales y por la profunda reforma del sistema portuario nacional que posibilitó el ingreso de la participación privada en la inversión de infraestructura, gestión y operación de terminales de cruceros. En este contexto se ha redefinido la organización espacial del turismo de cruceros con nuevas rutas que articulan diferentes puertos de origen y escalas que han posicionado a México como destino líder mundial en arribo de cruceros. De esta forma, el objetivo del presente artículo es examinar las condiciones que han propiciado la dinámica espacio-temporal del turismo de cruceros en el país, que conduzca a una revisión crítica de la nueva geografía regional de los cruceros turísticos en México.
Mexique

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5077
http://journals.openedition.org/etudescaribeennes/5077