Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Peridotite xenoliths with a broad range of textures provides evidence for consistent microstructural evolution in a vertical transect of the shallow lithospheric mantle (35?55 km depth) beneath the Persani Mountains, SE Carpathians, Romania, due to ongoing plate convergence in the Carpathian Arc nearby. The recrystallized grain size, crystal preferred orientations strength, and resulting seismic anisotropy vary continuously and display a strong correlation to equilibrium temperatures, suggesting a continuous change in deformation conditions with depth. The shallowmost xenoliths have microstructures typical of high stress deformation, marked by strong recrystallization to fine grain sizes, which results in weak crystal preferred orientations and anisotropy. The deepest xenoliths have coarse-grained porphyroclastic microstructures and strong crystal preferred orientations. Replacive orthopyroxene structures, consuming olivine, and high H2O concentrations in the pyroxenes are observed in some xenoliths indicating limited percolation of fluids or volatile-rich melts. Despite the high stress deformation and high H2O contents in some of the studied xenoliths, analysis of olivine crystallographic orientations indicates that [100] slip systems, rather than ?wet? [001] accommodate most of the deformation in all samples. Seismic anisotropy estimated from the measured olivine and pyroxene crystal preferred orientations suggests that the strike-parallel fast SKS polarization directions and ~ 1 s delay times measured in the SE Carpathians are likely the consequence of convergence-driven belt-parallel flow in the lithospheric mantle.
ISSN: 0012-821X

hal-00317303
https://hal.archives-ouvertes.fr/hal-00317303
DOI : 10.1016/J.EPSL.2008.04.035

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Ash flow tuffs, or ignimbrites have been recently proposed to be a good material for palaeointensity determination. In this paper, we present a multidisciplinary study, combining geochronology, petrology, rock magnetism and palaeomagnetism, carried out on Oligocene to Early Miocene ignimbrites and related flows from the southern part of the Sierra Madre Occidental. Two new 40Ar/39Ar ages were determined for ignimbrites; 20.4 ± 0.2 Ma (the youngest age obtained so far in this area) and 29.2 ± 0.5 Ma. Density measurements, as a proxy for welding, proved to be extremely useful to estimate the emplacement temperature and the origin of the magnetizations carried by the ignimbrites. After alternating field and thermal demagnetizations, the mean palaeomagnetic pole (Lat = 66.8°N; Long = 180.5°E; Kappa = 142; A95 = 6.3°), calculated for the period 28-31 Ma, is in close agreement with our only Miocene determination. Comparison with the North America Synthetic Apparent Polar Path indicates a net counter-clockwise vertical axis rotation of about 10 ± 4° compared to stable North America, which occurred likely during the last extensional episode in the Late Miocene (ca. 12-9 Ma). Palaeointensity estimates, obtained with the Thellier-Coe method, are mainly questionable and should not be used for global interpretation. Therefore, these ignimbrites are not a viable material for reliable palaeointensity determinations.
ISSN: 0956-540X

hal-00854457
https://hal.archives-ouvertes.fr/hal-00854457
DOI : 10.1093/gji/ggt079

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The morphogenetic evolution of the Lesser Caucasus has been strongly influenced by Plio-Quaternary volcanic and tectonic events and Pleistocene glaciations. Fluvio-lacustrine environments, indicated by diatomaceous deposits, prevailed in the Syunik region of southern Armenia during the Pliocene and Pleistocene. The Pleistocene diatomaceous deposits studied contain leaf impressions and pollen, allowing local palaeoclimatic reconstructions. The chronology of morphogenetic events has been determined by 17 radiometric dates (K/Ar, Ar/Ar, U/Th), palaeomagnetic investigations and is placed in a spatial context by a detailed geomorphological map and a 24-km geological transect of the Vorotan valley, the main area studied. Before 1.21 Ma, tectonic movements (antecedents of the lower part of the Vorotan valley) generated extensive lake formations with diatomaceous deposits. From 993 ka, volcanic eruptions produced lava flows that covered the fluvio-lacustrine accumulations. During Marine Isotopic Stages 12, 6 and 4, glaciers and fluvio-glacial deposits were probably present overall the principal uplands and valleys of southern Armenia. At 53.68 ka (MIS 3), 12.6 ka, 10.78 ka and 4.14 ka (MIS 1), the development of travertines on some slopes and in some valleys highlights temperate and humid climatic phases. Palaeobotanical studies of leaf and pollen floras show that the vegetation changed several times from forested to steppic phases in response to the climate oscillations of the Lower Pleistocene. This work proposes a first morphogenic and palaeoclimatic reconstruction from the lower Pleistocene to the Postglacial period, when the first settlements of the population in the Lesser Caucasus were influenced by tectono-volcanic events, lake level changes and glacialeinterglacial oscillations forced by the obliquity orbital parameter (41 ky cycles).
ISSN: 1040-6182

hal-00481939
https://hal.archives-ouvertes.fr/hal-00481939
DOI : 10.1016/j.quaint.2010.02.008

Éditeur(s) : HAL CCSD
Résumé : International audience
The tourist activity, by its international character and as a constantly expanding economic sector emerges as a means of obtaining international recognition being meanwhile an important economic sector of the national economy. In Romania case it appears as an "air breath" for an economic system in crisis and an extremely rolonged period of transition. By the dynamics, human and financial flow which it triggers, through the multiple forms which it covers, through the ability by which some thresholds (i.e. ideological or political) can impose an evolving path, tourism represents an economic sector for the countries in transition which can re-lauch or re-direct the subsequent evolution of a national economy. In ordeur to reach to these parameters a re-definition and a re-discovery of the real tourist potential is required in Romania case.
Condtions of the Foreign Tourism Developement in Central and Eastern Europe. Problems of the Development of Ecotourism with Special Emphasis on Mountain Areas

ISBN : 83-87196-28-2
hal-01412866
https://hal.univ-antilles.fr/hal-01412866
https://hal.univ-antilles.fr/hal-01412866/document
https://hal.univ-antilles.fr/hal-01412866/file/2002%20Alternatives%20for%20the%20development%20of%20tourism%20in%20Romania.pdf

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Staphylococcus aureus is a highly versatile, opportunistic pathogen and the etiological agent of a wide range of infections in humans and warm-blooded animals. The epithelial surface is its principal site of colonization and infection. In this work, we investigated the cytopathic effect of S. aureus strains from human and animal origins and their ability to affect the host cell cycle in human HeLa and bovine MAC-T epithelial cell lines. S. aureus invasion slowed down cell proliferation and induced a cytopathic effect, resulting in the enlargement of host cells. A dramatic decrease in the number of mitotic cells was observed in the infected cultures. Flow cytometry analysis revealed an S. aureus-induced delay in the G2/M phase transition in synchronous HeLa cells. This delay required the presence of live S. aureus since the addition of the heat-killed bacteria did not alter the cell cycle. The results of Western blot experiments showed that the G2/M transition delay was associated with the accumulation of inactive cyclin-dependent kinase Cdk1, a key inducer of mitosis entry, and with the accumulation of unphosphorylated histone H3, which was correlated with a reduction of the mitotic cell number. Analysis of S. aureus proliferation in asynchronous, G1- and G2-phase-enriched HeLa cells showed that the G2 phase was preferential for bacterial infective efficiency, suggesting that the G2 phase delay may be used by S. aureus for propagation within the host. Taken together, our results divulge the potential of S. aureus in the subversion of key cellular processes such as cell cycle progression, and shed light on the biological significance of S. aureus-induced host cell cycle alteration.
ISSN: 1932-6203

hal-00873672
https://hal.archives-ouvertes.fr/hal-00873672
https://hal.archives-ouvertes.fr/hal-00873672/document
https://hal.archives-ouvertes.fr/hal-00873672/file/Staphylococcus_aureus-Induced.accepted.pdf
DOI : 10.1371/journal.pone.0063279

Éditeur(s) : HAL CCSD American Physiological Society
Résumé : International audience
Zidi-Yahiaoui N, Callebaut I, Genetet S, Le Van Kim C, Cartron JP, Colin Y, Ripoche P, Mouro-Chanteloup I. Functional analysis of human RhCG: comparison with E. coli ammonium transporter reveals similarities in the pore and differences in the vestibule. Am J Physiol Cell Physiol 297: C537–C547, 2009. First published June 24, 2009; doi:10.1152/ajpcell.00137.2009.—Rh glycoproteins are members of the ammonium transporter (Amt)/methylamine permease (Mep)/Rh family facilitating movement of NH3 across plasma membranes. Homology models constructed on the basis of the experimental structures of Escherichia coli AmtB and Nitrosomonas europaea Rh50 indicated a channel structure for human RhA (RhAG), RhB (RhBG), and RhC (RhCG) glycoproteins in which external and internal vestibules are linked by a pore containing two strictly conserved histidines. The pore entry is constricted by two highly conserved phenylalanines, “twin-Phe.” In this study, RhCG function was investigated by stopped-flow spectrofluorometry measuring kinetic pH variations in HEK293E cells in the presence of an ammonium gradient. The apparent unitary NH3 permeability of RhCG was determined and was found to be close to that of AmtB. With a site-directed mutagenesis approach, critical residues involved in Rh NH3 channel activity were highlighted. In the external vestibule, the importance of both the charge and the conformation of the conserved aspartic acid was shown. In contrast to AmtB, individual mutations of each phenylalanine of the twin-Phe impaired the function while the removal of both resulted in recovery of the transport activity. The impact of the mutations suggests that, although having a common function and a similar channel structure, bacterial AmtB and human Rh vary in several aspects of the NH3 transport mechanisms.
ISSN: 0363-6143

hal-00417492
https://hal.archives-ouvertes.fr/hal-00417492
DOI : 10.1152/ajpcell.00137.2009.

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Tropical islands are characterized by thermal and orographical forcings which may generate microscale air mass circulations. The Lesser Antilles Arc includes small tropical islands (width lower than 50 km) where a total of one-and-a-half million people live. Air quality over this region is affected by anthropogenic and volcanic emissions, or saharan dust. To reduce risks for the population health, the atmospheric dispersion of emitted pollutants must be predicted. In this study, the dispersion of anthropogenic nitrogen oxides (NOx) is numerically modelled over the densely populated area of the Guadeloupe archipelago under weak trade winds, during a typical case of severe pollution. The main goal is to analyze how microscale resolutions affect air pollution in a small tropical island. Three resolutions of domain grid are selected: 1 km, 333 m and 111 m. The Weather Research and Forecasting model (WRF) is used to produce real nested microscale meteorological fields. Then the weather outputs initialize the Lagrangian Particle Dispersion Model (FLEXPART). The forward simulations of a power plant plume showed good ability to reproduce nocturnal peaks recorded by an urban air quality station. The increase in resolution resulted in an improvement of model sensitivity. The nesting to subkilometer grids helped to reduce an overestimation bias mainly because the LES domains better simulate the turbulent motions governing nocturnal flows. For peaks observed at two air quality stations, the backward sensitivity outputs identified realistic sources of NOx in the area. The increase in resolution produced a sharper inverse plume with a more accurate source area. This study showed the first application of the FLEXPART-WRF model to microscale resolutions. Overall, the coupling model WRF-LES-FLEXPART is useful to simulate the pollutant dispersion during a real case of calm wind regime over a complex terrain area. The forward and backward simulation results showed clearly that the subkilometer resolution of 333 m is necessary to reproduce realistic air pollution patterns in this case of short-range transport over a complex terrain area. Globally, this work contributes to enrich the sparsely documented domain of real nested microscale air pollution modelling. This study dealing with the determination of the proper resolution grid and proper turbulence scheme, is of significant interest to the near-source and complex terrain air quality research community.
ISSN: 1352-2310

hal-01349208
https://hal.archives-ouvertes.fr/hal-01349208
DOI : 10.1016/j.atmosenv.2016.05.028

Éditeur(s) : Wiley-blackwell
Résumé : The history of colonization and dispersal in fauna distributed among deep-sea chemosynthetic ecosystems remains enigmatic and poorly understood because of an inability to mark and track individuals. A combination of molecular, morphological and environmental data improves understanding of spatial and temporal scales at which panmixia, disruption of gene flow or even speciation may occur. Vestimentiferan tubeworms of the genus Escarpia are important components of deep -sea cold seep ecosystems, as they provide long-term habitat for many other taxa. Three species of Escarpia, Escarpia spicata [Gulf of California (GoC)], Escarpia laminata [Gulf of Mexico (GoM)] and Escarpia southwardae (West African Cold Seeps), have been described based on morphology, but are not discriminated through the use of mitochondrial markers (cytochrome oxidase subunit 1; large ribosomal subunit rDNA, 16S; cytochrome b). Here, we also sequenced the exon-primed intron-crossing Haemoglobin subunit B2 intron and genotyped 28 microsatellites to (i) determine the level of genetic differentiation, if any, among the three geographically separated entities and (ii) identify possible population structure at the regional scale within the GoM and West Africa. Results at the global scale support the occurrence of three genetically distinct groups. At the regional scale among eight sampling sites of E. laminata (n=129) and among three sampling sites of E. southwardae (n=80), no population structure was detected. These findings suggest that despite the patchiness and isolation of seep habitats, connectivity is high on regional scales.
Molecular Ecology (0962-1083) (Wiley-blackwell), 2013-08 , Vol. 22 , N. 16 , P. 4147-4162

Droits : 2013 John Wiley & Sons Ltd
http://archimer.ifremer.fr/doc/00152/26354/24515.pdf
DOI:10.1111/mec.12379
http://archimer.ifremer.fr/doc/00152/26354/

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Les facteurs répulsifs de l’émigration haïtienne ont complètement changé depuis les années 1950 qui marquèrent le début de ce mouvement avec le régime duvaliériste. Les entités géopolitiques et sociopolitiques qui en résultent évoluent, elles aussi, proportionnellement et rationnellement aux motivations des individus en partance. Ainsi, les exilés forcés rêvaient de retrouver leur chère Haïti, les nouveaux primo-arrivants sont des individus qui cherchent à se ré-enraciner dans un terreau aux airs d’ailleurs. Le diasporique est-il un individu dont l’identité est figée ? Dans cet article, une étude statistique simple cherche à démontrer l’évolution des mentalités des jeunes Haïtiens à travers un questionnement des identités et des orientations culturelles. Des dynamiques se font jour montrant que la diaspora est fluctuante comme les identités et les cultures qui la composent.
The Push factors of Haitian emigration have completely changed since the late 1950s which marked the beginning of this movement with the Duvalier regime. The geopolitical and sociopolitical entities which result from it are changing as well, in proportion and accordance with the motivations of the people who leave. Thus, the forced exiles dreamt of going back to their dearest Haiti, the latest newly-arrived immigrants are individuals who desire to re-root into a land that sounds like “elsewhere”. Must the diasporic individual’s identity be stable? In this article, a simple survey seeks to shed light on the changing mentalities of young Haitians, examining their identities and cultural choices. Emerging trends show that diaspora is a flow, not unlike the identities and the cultures of which it is composed.
New York

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.4628
http://journals.openedition.org/etudescaribeennes/4628

Éditeur(s) : HAL CCSD American Geophysical Union
Résumé : International audience
We present the results of a paleomagnetic study of seven new volcanic sections (146 flows) from Kerguelen Archipelago. For two of these sections, preliminary (;40;Ar/;39;Ar) ages are reported to aid in the calibration of the paleomagnetic results. The primary contribution of this report, however, is a compilation of these new data with those already published in order to describe statistically the characteristics of the paleomagnetic field as recorded by the Kerguelen flood basalts. In total, 258 paleomagnetic directions sampled at 13 stratigraphic sections through the lava pile are available and span an approximately 5 Ma window: from 25 to 30 Ma. The composite section represents at least 11 polarity zones that are correlated to the reference geomagnetic polarity timescale. Our approach is to investigate the average normal and reversed polarity field directions over this 5 Ma window. We calculated a paleomagnetic pole found to be located at ;λ; = 85.5°N, = 189.3°E (A;95; = 2.3°, K = 16.5, N = 233). This pole is in close agreement with the coeval paleomagnetic poles obtained from different worldwide places when analyzed in the Indo-Atlantic hot spot reference frame. In the statistical analysis we tackle the specific question: Is the secular variation isotropic? This question is directly related to the occurrence of a longitudinal confinement of the virtual geomagnetic poles, which is still a matter of debate among paleomagnetists. By means of statistical tests we show that the paleomagnetic data from Kerguelen agree with an isotropic model for paleosecular variation. Finally, we present adjustments to Camps and Prévot's (1996) statistical model, developed for some Northern Hemisphere latitudes, to the Southern Hemisphere paleomagnetic data from Kerguelen.
ISSN: 0148-0227

hal-00407636
https://hal.archives-ouvertes.fr/hal-00407636
https://hal.archives-ouvertes.fr/hal-00407636/document
https://hal.archives-ouvertes.fr/hal-00407636/file/pcamps-JGR2007.pdf
DOI : 10.1029/2006JB004648

Éditeur(s) : HAL CCSD Society for Industrial and Applied Mathematics
Résumé : International audience
In this paper, we developed a theoretical study for nonconservative sytems in one dimension in order to construct numerical schemes for solving the Riemann problem. The nonconservative form of our model system required the use of a well-adapted theory in order to give us a sense of our problem. We chose a framework of generalized functions for solving a scalar hyperbolic equation with a discontinuous coefficient $sigma_t +usigma_x approx 0$, where u is the velocity solution of a Burgers's equation. After an explicit solution of the Riemann problem, we derived Godunov split schemes for computing an approximate solution of the Cauchy problem. We applied our study to a system modeling elasticity and a system modeling gas dynamics. Some stability properties of a scheme and its convergence to a generalized solution are proved for the first model. Numerical experiments confirmed this convergence result. For the second model, calculations of flows containing weak-to-moderate shocks showed that conservation errors are reduced when the mesh is refined but were not entirely eliminated.
ISSN: 0036-1429

hal-00770266
https://hal.univ-antilles.fr/hal-00770266
DOI : 10.1137/S0036142900378637

Éditeur(s) : HAL CCSD Mineralogical Society of America
Résumé : International audience
Hydrogen distribution between nominally anhydrous minerals (NAMs) of a garnet-lherzolite under subsolidus conditions has been investigated. Separated NAMs from a garnet-peridotite from Patagonia (Chile) are annealed together (olivine, orthopyroxene, clinopyroxene, and garnet) using a piston-cylinder at 3 GPa and 1100 °C using talc-pyrex cell assembly for 10, 25, and 100 h. The talc-pyrex assembly provides enough hydrogen in the system to re-equilibrate the hydrogen concentrations at high pressure. The three coexisting nominally anhydrous minerals (NAMs, i.e., olivine, orthopyroxene, and clinopyroxene) were successfully analyzed using FTIR. The resulting hydrogen concentrations exceed significantly the initial hydrogen concentration by a factor of 13 for olivine and a factor of 3 for both pyroxenes. Once mineral-specific infrared calibrations are applied, the average concentrations in NAMs are 115 ± 12 ppm wt H2O for olivine, 635 ± 75 ppm wt H2O for orthopyroxene, and 1214 ± 137 ppm wt H2O for clinopyroxene, garnet grains are dry. Since local equilibrium seems achieved over time (for 100 h), the calculated concentration ratios are interpreted as mineral-to-mineral hydrogen partition coefficients (i.e., Nernst’s law) for a garnet-peridotite assemblage. It yields, based on mineral-specific infrared calibrations, DOpx/Ol = 5 ± 1, DCpx/Ol = 10 ± 2, and DCpx/Opx = 1.9 ± 0.4. While DCpx/Opx is in agreement (within error) with previous results from experimental studies and concentration ratios observed in mantle-derived peridotites, the DPx/Ol from this study are significantly lower than the values reported from mantle-derived xenoliths and also at odd with several previous experimental studies where melt and/or hydrous minerals co-exists with NAMs. The results confirm the sensitivity of hydrogen incorporation in olivine regarding the amount of water-derived species (H) in the system and/or the amount of water in the coexisting silicate melt. The results are in agreement with an important but incomplete dehydration of mantle-derived olivine occurring at depth, during transport by the host magma or during slow lava flow cooling at the surface. The rapid concentration modification in mantle pyroxenes also points out that pyroxenes might not be a hydrogen recorder as reliable as previously thought.
ISSN: 0003-004X

hal-01622132
https://hal.archives-ouvertes.fr/hal-01622132
DOI : 10.2138/am-2017-6089

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
The chemical and isotopic compositions of clay minerals such as illite and chlorite are commonly used to quantify diagenetic and low-grade metamorphic conditions, an approach that is also used in the present study of the Monte Perdido thrust fault from the South Pyrenean fold-and-thrust belt. The Monte Perdido thrust fault is a shallow thrust juxtaposing upper Cretaceous-Paleocene platform carbonates and Lower Eocene marls and turbidites from the Jaca basin. The core zone of the fault, about 6 m thick, consists of intensely deformed clay-bearing rocks bounded by major shear surfaces. Illite and chlorite are the main hydrous minerals in the fault zone. Illite is oriented along cleavage planes while chlorite formed along shear veins (<50 μm in thickness). Authigenic chlorite provides essential information about the origin of fluids and their temperature. δ18O and δD values of newly formed chlorite support equilibration with sedimentary interstitial water, directly derived from the local hanging wall and footwall during deformation. Given the absence of large-scale fluid flow, the mineralization observed in the thrust faults records the P-T conditions of thrust activity. Temperatures of chlorite formation of about 240°C are obtained via two independent methods: chlorite compositional thermometers and oxygen isotope fractionation between cogenetic chlorite and quartz. Burial depth conditions of 7 km are determined for the Monte Perdido thrust reactivation, coupling calculated temperature and fluid inclusion isochores. The present study demonstrates that both isotopic and thermodynamic methods applied to clay minerals formed in thrust fault are useful to help constrain diagenetic and low-grade metamorphic conditions.
ISSN: 0010-7999

hal-00757736
https://hal.archives-ouvertes.fr/hal-00757736
DOI : 10.1007/s00410-011-0718-0

Éditeur(s) : Marine Biological Laboratory
Résumé : Hydrothermal vent tubeworms, Riftia pachyptila Jones, were maintained alive and studied on board ship using flow-through pressure aquaria. Simultaneous measurements of O2, SIGMA-CO2, SIGMA-H2S fluxes showed that the intact symbioses reach maximum rates of uptake of SIGMA-CO2 (>2 mu-mole g-1 h-1) at about 90 mu-M SIGMA-H2S. Measurements were made of hemolymph and coelomic fluid SIGMA-CO2, SIGMA-H2S, thiosulfate, pH, and hemoglobin concentrations in worms kept under various conditions of O2 and SIGMA-H2S. Normal hemolymph pH appears to be about 7.5 and is not affected by SIGMA-H2S and SIGMA-CO2 concentrations within the ranges observed. We conclude that Riftia is specialized to provide sulfide to its symbionts with minimal interaction of sulfide with the animal metabolism. The uptake of sulfide is apparently by diffusion into the hemolymph, facilitated by the sulfide-binding properties of the hemoglobins. Both SIGMA-CO2 and P(CO2) are elevated in the hemolymph above their levels in the medium, although they are reduced under autotrophic conditions. Thus inorganic carbon is apparently concentrated from the medium into the hemolymph by an unknown mechanism.
Biological Bulletin (0006-3185) (Marine Biological Laboratory), 1991-02 , Vol. 180 , N. 1 , P. 135-153

Droits : 1991 Marine Biological Laboratory
http://archimer.ifremer.fr/doc/00178/28970/27392.pdf
DOI:10.2307/1542437
http://archimer.ifremer.fr/doc/00178/28970/

Éditeur(s) : HAL CCSD Wiley-Blackwell
Résumé : International audience
Sinkholes are frequently observed where soluble rocks are present, in meteoritic recharge areas or when subsurface dissolution causes ground collapse. Seismic profiles on the inner shelf of the Gulf of Lions (W. Mediterranean) display a giant atypical sub-circular structure, up to 800-m thick and 2-km wide. It is characterized by down-warped internal seismic reflections forming a concave V-shaped depression rooted in the substratum, most likely carbonated. This structure is interpreted as a poly-phased solution-subsidence/collapse structure of Plio-Quaternary age. The last phase of deformation probably occurred during the last sea-level low-stand phase. The mechanism proposed for the creation of this structure is collapse/dissolution of the soluble substratum, as a result of a combination of several possible factors including pre-existing deep Messinian palaeo-karst with active groundwater flows during Plio-Quaternary lowstands, and deep-rooted acidic fluids ascending through the substratum.
ISSN: 0954-4879

hal-00758063
https://hal.archives-ouvertes.fr/hal-00758063
DOI : 10.1111/j.1365-3121.2011.01051.x

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Sickle cell anemia (SCA) and hemoglobin SC (HbSC) disease are the two most common forms of sickle cell disease (SCD), a frequent hemoglobinopathy which exhibits a highly variable clinical course. Although high levels of microparticles (MPs) have been consistently reported in SCA and evidence of their harmful impact on the SCA complication occurrences have been provided, no data on MP pattern in HbSC patients has been reported so far. In this study, we determined and compared the MP patterns of 84 HbSC and 96 SCA children, all at steady-state, using flow cytometry. Most of circulating MPs were derived from platelets (PLTs) and red blood cells (RBCs) in the two SCD syndromes. Moreover, we showed that HbSC patients exhibited lower blood concentration of total MPs compared to SCA patients, resulting mainly from a decrease of MP levels originated from RBCs and to a lesser extent from PLTs. We did not detect any association between blood MP concentrations and the occurrence of painful vaso-occlusive crises, acute chest syndrome and pulmonary hyper-tension in both patient groups. We also demonstrated for the first time, that whatever the considered genotype, RBC-derived MPs exhibited higher externalized phosphatidylserine level and were larger than PLT-derived MPs.
ISSN: 1932-6203

hal-01668322
https://hal.univ-antilles.fr/hal-01668322
https://hal.univ-antilles.fr/hal-01668322/document
https://hal.univ-antilles.fr/hal-01668322/file/journal.pone.0177397.pdf
DOI : 10.1371/journal.pone.0177397

Éditeur(s) : HAL CCSD
Résumé : International audience
The deformation of natural systems in response to subsurface water storage and redistribution provides insightsinto the main water flow path within heterogeneous systems, including the role of faults or fractures. A longbaseline tiltmeter was installed in the low-noise underground laboratory of Rustrel (LSBB) to study the responseof the Fontaine de Vaucluse (FDV) karst hydrosystem to water cycle. Tilt data and piezometric levels recorded in aborehole close to the LSBB show a strong correlation with the discharge of the system observed at the FDV spring30 km away. Over several months, tilt data were recorded on three base lines, thus allowing, for the first time,to study the tilt gradient variation that appears homogeneous. Such information provides a significant constrainton hydrological processes leading to the measured deformation. Several deformation models were tested usingthe ADELI code to estimate the type of hydro-mechanical structure that could reproduce the measured tilt andits gradient. On one hand, models show that uniform loading at the surface produces a much smaller signal thanobserved on measured data. On the other hand, the deformation related to the filling of a fracture following aprecipitation event requires unrealistic fracture size. Finally, we found that a suitable hydro-mechanical modelcorresponds to the loading of numerous fractures at the interface between the saturated and unsaturated zones. Sucha configuration predicts a tilt distribution in agreement with observations. This study suggests that tilt networksinto a karst system should provide key observation for deciphering hydrological processes
Geophysical Research Abstracts
Vienne, Austria

insu-01308594
https://hal-insu.archives-ouvertes.fr/insu-01308594

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The number of satellites and sensors devoted to Earth observation has become increasingly elevated, delivering extensive data, especially images. At the same time, the access to such data and the tools needed to process them has considerably improved. In the presence of such data flow, we need automatic image interpretation methods, especially when it comes to the monitoring and prediction of environmental and societal changes in highly dynamic socio-environmental contexts. This could be accomplished via artificial intelligence. The concept described here relies on the induction of classification rules that explicitly take into account structural knowledge, using Aleph, an Inductive Logic Programming (ILP) system, combined with a multi-class classification procedure. This methodology was used to monitor changes in land cover/use of the French Guiana coastline. One hundred and fifty-eight classification rules were induced from 3 diachronic land cover/use maps including 38 classes. These rules were expressed in first order logic language, which makes them easily understandable by non-experts. A 10-fold cross-validation gave significant average values of 84.62%, 99.57% and 77.22% for classification accuracy, specificity and sensitivity, respectively. Our methodology could be beneficial to automatically classify new objects and to facilitate object-based classification procedures.
ISSN: 0098-3004

hal-01369822
https://hal.archives-ouvertes.fr/hal-01369822
https://hal.archives-ouvertes.fr/hal-01369822/document
https://hal.archives-ouvertes.fr/hal-01369822/file/CAGEO-D-13-00538R1_article.pdf
DOI : 10.1016/j.cageo.2014.08.013

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The characteristic frequencies at which two different melt-related attenuation mechanisms occur in partially molten gabbronorite are computed as a function of aspect ratios of the melt-filled cracks, and the melt viscosity. The computations were done for basaltic and andesitic melts. The melt viscosity is constrained by (i) laboratory measurements performed in the range 10(8)-10(14) Pa s with a creep apparatus and in the range 10(-1) to 10(5) Pas with a rotational Couette viscorneter, and (ii) modeling of viscosity at high temperatures. The results of the characteristic frequency calculations suggest that melt squirt flow is a viable attenuation mechanism at seismic frequencies for aspect ratio of melt inclusions in the range 10(-1) to 10(-2) for the andesite, and 10(-4) to 10(-3) for the two basalts.
ISSN: 0031-9201

hal-00412014
https://hal.archives-ouvertes.fr/hal-00412014
DOI : 10.1016/j.pepi.2008.04.010

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The mucosal events of HIV transmission have been extensively studied, but the role of infected cells present in the genital and rectal secretions, and in the semen, in particular, remains a matter of debate. As a prerequisite to a thorough in vivo investigation of the early transmission events through infected cells, we characterized in detail by multi-parameter flow cytometry the changes in macaque seminal leukocytes during SIVmac251 infection, focusing on T cells, macrophages and dendritic cells. Using immunocytofluorescence targeting SIV proteins and real-time quantitative PCR targeting SIV DNA, we investigated the nature of the infected cells on sorted semen leukocytes from macaques at different stages of infection. Finally, we cocultured semen CD4(+) T cells and macrophages with a cell line permissive to SIV infection to assess their infectivity in vitro. We found that primary infection induced strong local inflammation, which was associated with an increase in the number of leukocytes in semen, both factors having the potential to favor cell-associated virus transmission. Semen CD4(+) T cells and macrophages were productively infected at all stages of infection and were infectious in vitro. Lymphocytes had a mucosal phenotype and expressed activation (CD69 & HLA-DR) and migration (CCR5, CXCR4, LFA-1) markers. CD69 expression was increased in semen T cells by SIV infection, at all stages of infection. Macrophages predominated at all stages and expressed CD4, CCR5, MAC-1 and LFA-1. Altogether, we demonstrated that semen contains the two major SIV-target cells (CD4+ T cells and macrophages). Both cell types can be productively infected at all stages of SIV infection and are endowed with markers that may facilitate transmission of infection during sexual exposure.
ISSN: 1553-7366

hal-00955292
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00955292
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00955292/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00955292/file/Semen_CD4_T-accepted.pdf
PUBMED : 24348253