Éditeur(s) : Wiley-blackwell Publishing, Inc
Résumé : Vibrio splendidus, strain LGP32, is an oyster pathogen associated with the summer mortalities affecting the production of Crassostrea gigas oysters worldwide. Vibrio splendidus LGP32 was shown to resist to up to 10 mu M Cg-Def defensin and Cg-BPI bactericidal permeability increasing protein, two antimicrobial peptides/proteins (AMPs) involved in C. gigas immunity. The resistance to both oyster Cg-Def and Cg-BPI and standard AMPs (polymyxin B, protegrin, human BPI) was dependent on the ompU gene. Indeed, upon ompU inactivation, minimal bactericidal concentrations decreased by up to fourfold. AMP resistance was restored upon ectopic expression of ompU. The susceptibility of bacterial membranes to AMP-induced damages was independent of the ompU-mediated AMP resistance. Besides its role in AMP resistance, ompU proved to be essential for the adherence of V. splendidus LGP32 to fibronectin. Interestingly, in vivo, ompU was identified as a major determinant of V. spiendidus pathogenicity in oyster experimental infections. Indeed, the V. splendidus-induced oyster mortalities dropped from 56% to 11% upon ompU mutation (Kaplan Meier survival curves, P < 0.01). Moreover, in co-infection assays, the ompU mutant was out competed by the wild-type strain with competitive indexes in the range of 0.1-0.2. From this study, ompU is required for virulence of V. splendidus. Contributing to AMP resistance, conferring adhesive properties to V. splendidus, and being essential for in vivo fitness, the OmpU porin appears as an essential effector of the C. gigas/V. splendidus interaction.
Environmental Microbiology (1462-2912) (Wiley-blackwell Publishing, Inc), 2010-04 , Vol. 12 , N. 4 , P. 951-963

Droits : 2010 Society for Applied Microbiology and Blackwell Publishing Ltd
http://archimer.ifremer.fr/doc/00003/11421/8044.pdf
DOI:10.1111/j.1462-2920.2009.02138.x
http://archimer.ifremer.fr/doc/00003/11421/

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
BACKGROUND: The potential interest of antifungal treatment of non-immunocompromized patients with sepsis, extra-digestive Candida colonization and multiple organ failure is unknown. It represents three-quarters of antifungals prescribed in Intensive Care Units. It may allow early treatment of invasive fungal infection in the incubation phase but expose patients to unnecessary antifungal treatments with subsequent cost and fungal selection pressure. As early diagnostic tests for invasive candidiasis are still considered to be insufficient, the potential interest in this strategy needs to be demonstrated. METHODS: This prospective multicenter, double blind, randomized-controlled trial is conducted in 23 French Intensive Care Units. All adult patients, mechanically ventilated for more than four days with sepsis of unknown origin and with at least one extradigestive fungal colonization site and multiple organ failure are eligible for randomization. Patients with proven invasive candidiasis are not included. After a complete mycological screening, patients are allocated to receive micafungin 100 mg intravenously once a day or placebo for 14 days. We plan to enroll 260 patients. The main objective is to demonstrate that micafungin increases survival of patients without invasive candidiasis at day 28 as compared to placebo. Other outcomes include day 28 and 90 survival and organ failure evolution. Additionally, pharmacokinetics of micafungin in enrolled patients will be measured and evolution of fungal biomarkers and susceptibility profiles of infecting fungi will also be followed. DISCUSSION: This study will help to provide guidelines for treating non-immunocompromized patients with fungal colonization multiple organ failure and sepsis of unknown origin.Trial registration: Clinicaltrials.gov number NCT01773876.
ISSN: 1745-6215

inserm-00913515
http://www.hal.inserm.fr/inserm-00913515
http://www.hal.inserm.fr/inserm-00913515/document
http://www.hal.inserm.fr/inserm-00913515/file/1745-6215-14-399.pdf
PUBMED : 24261608

Éditeur(s) : Neidine editeurs
Résumé : This article calls back first of all a set of facts relative to the main stakes considering sea and ocean so much on the economic point of view, in the scientific technological and innovative fields, in the governance aspects as also in the culture and international prestige ones. Then the article synthesizes several of the elements of the European study on the blue growth, the established priorities, the results of the study and its recommendations. The case of New Caledonia is then analyzed which shows that considering the 11 economic priorities identified by the European Union, 10 interest or may interest this ultra-marine country. A focus is proposed on a second European study which concerns the implementation of a Blue Society (Sea for Society Project) and in synthesis and perspectives the authors wonder about the possibilities and the profits which New Caledonia could take advantage of the implementation of a maritime and marine strategy based on the principles of blue growth and blue society.
Cet article rappelle tout d’abord un ensemble de faits relatifs aux grands enjeux de la maritimisation tant au plan de l’économie, de la science, de la technologie et de l’innovation, de la gouvernance comme également de la culture et du rayonnement international. Ensuite l’article synthétise plusieurs des éléments de l’étude européenne sur la croissance bleue, les priorités établies, les résultats de l’étude et ses recommandations. Le cas de la Nouvelle-Calédonie est alors abordé qui montre que sur les 11 priorités économiques identifiées par l’Europe, 10 intéressent ou sont susceptible d’intéresser ce pays ultra-marin. Un focus est proposé sur une seconde étude européenne qui concerne la mise en place d’une Société Bleue et en synthèse et perspectives les auteurs s’interrogent sur les possibilités et bénéfices que la Nouvelle-Calédonie pourrait tirer de la mise en place d’une stratégie maritime et marine basée sur les principes de croissance et de société bleues.
Tai Kona (2269-7535) (Neidine editeurs), 2013-11 , N. 5 , P. 12-35

Droits : Tai Kona
http://archimer.ifremer.fr/doc/00174/28505/26854.pdf
http://archimer.ifremer.fr/doc/00174/28505/

Résumé : Don Vicente was entertaining Ignacio Haya, a manufacturing friend from New York, when Gargol and Gutierrez arrived. Haya, of the firm Sanchez and Haya, had come to Key West for both business and pleasure; he always enjoyed the warm Florida climate. Sr. Haya was also there to discuss business. Both he and Ybor were constantly being threatened with labor strikes which could cripple their operations. Haya saw the problem as so serious that he had already dispatched his associate, Serafin Sanchez, to search for other possible locations to open branch factories.8 Don Vicente was also confronted with labor hostility in Key West, and he too wanted to move to a location where labor was not organized. They were undoubtedly influenced by other manufacturers who were forming company towns, away from the crowded cities, as a means of accelerating production and limiting union influence. Ybor and Haya sent inquiries to Galveston, Mobile, and Pensacola, expressing their interests in possibly locating in one of those cities. Don Vicente had earlier learned about Tampa from Edward Manrara, but had not yet given it serious consideration as a possible location for a branch factory; not until the visit of Gutierrez and Gargol.
(Funding) Funded in part by the Institute for Museum and Library Services (IMLS), Ephemeral Cities Project.
Tampa |z 1271000 |2 ceeus
Hillsborough County |z 12057 |2 ceeus
United States of America -- Florida -- Hillsborough County -- Tampa

Droits : All rights reserved. 2005.
C24-05713

Éditeur(s) : HAL CCSD Elsevier Elsevier Masson
Résumé : Thalattosuchia was a diverse clade of marine crocodylomorphs known from the Early Jurassic to the Early Cretaceous. Recent studies have hypothesized that their extinction was two-phased: (1) habitat loss near/at the Jurassic-Cretaceous boundary heavily reduced their morphofunctional diversity, particularly in Europe, while (2) climate change and a shift in marine fauna during the Early Cretaceous (either at the Valanginian-Hauterivian boundary or during the early Hauterivian) finished off the already stressed clade. Unfortunately, the Cretaceous fossil record of thalattosuchians is poor, with only one putative “teleosaurid” specimen and approximately ten metriorhynchid specimens. Here we re-describe the youngest known teleosaurid from the Cretaceous (Valanginian of south-eastern France). Originally considered to be a teleosaurid (possibly Steneosaurus), we demonstrate that it belongs to Metriorhynchidae, and a newly discovered subclade, Plesiosuchina. It differs from Plesiosuchus in the pattern of tooth enamel ornamentation and the variation in dentary alveoli size. Referring this specimen to Metriorhynchidae means there are no definitive Cretaceous teleosaurid specimens. Furthermore, it suggests that both durophagous and piscivorous teleosaurids became extinct at the end of the Jurassic. Interestingly, this is the fourth metriorhynchid lineage known to cross the Jurassic-Cretaceous boundary. As such, it would appear that the two thalattosuchian families responded very differently to the lowering sea levels at the end of the Jurassic: teleosaurids possibly became extinct, while metriorhynchids were seemingly unaffected.
ISSN: 0753-3969

hal-01122803
https://hal.archives-ouvertes.fr/hal-01122803
DOI : 10.1016/j.annpal.2014.01.002

Éditeur(s) : Hyacinth M. Simpson Hyacinth M. Simpson ( Manitoba, Canada )
Résumé : The word macomère is widely used by women in the Caribbean to mean "my child's godmother"; "my best friend and close female confindante"; "my bridesmaid, or another female wedding member of a wedding party of which I was a bridesmaid"; "the godmother of the child to whom I am also godmother"; "the woman who, by virtue of the depth of her friendship, has rights and privileges over my child and is a surrogate mother." This name seems appropriate because it so clearly expresses the intimate relations which women in the Caribbean share, is so firmly gendered, and honors the importance of friendship in relation to the important rituals of marriage, birth, and (implied) death. Moreover, macomère is a French Creole word which, although related to the French language, has taken on a structure and meaning which is indigenous to the Caribbean. The word is spelled in this way, instead of in the clearly Creole manner (macumè, makumeh, macoomè, macomeh, and many other variants), so that the female connotations of the word are highlighted and those meanings which apply to males ("a womanish or gossipy man"; "a homosexual") are less obvious. In those islands where Krèol (linguistic term for the French patos) is the first language, the same term is used for both females and males with meaning determined by the context. In islands such as Trinidad, however, where English has overlain Krèol, the Creole (linguistic term for the English patois) has incorporated the redundant my macomè and macomè man, thus reinforcing both the perceptions of intimacy and the female quality of the term. Interestingly enough, Richard Allsopp in The Dictionary of Caribbean English Usage (Oxford University Press, 1996) has indicated the possibility that maku in Belize, with the meaning "midwife", is also derived from macomère. Hence, the word forces us to recall the continuities and correspondences in Caribbean languages and cultures, as well as the dynamic, creative, and transforming power of Creoles. In the purely English-speaking islands, the only comparable term is godmother (usually the mother's best friend). In the Hispanophone Caribbean, there is the similar comadre, although, as we would expect, some of the connotations are different. Join us in continuing to interrogate all the connotations of the meaning inherent in this culturally rich lexical item from the Caribbean Creoles.

Droits : All rights reserved by the source institution.
39971238

Éditeur(s) : Actes de Colloque: Avancées et nouvellles technologies en toxinologie, éditeurs: Julien BARBIER, Evelyne BENOIT, Pascale MARCHOT, César MATTEI, Denis SERVENT
Résumé : Over the past seven years, methods available for the detection of phycotoxins have been extensively reviewed in a number of international expert committees, such as the consultations organised by FAO/IOC/WHO and EFSA, as well as by individual scientists. These reviews have shown that the methods available have severe limitations for the use in official control, either due to their limited scope and detection capability or due to a lack of calibration standards, reference materials and validation efforts. The present review focuses on recent developments in the detection of phycotoxins in several areas of applied research. Not being able to exhaustively describe all recent developments, the review focussed on three areas of interest to the authors: (i) detection of ultra-trace amounts of toxins, (ii) metabolism of toxins and their localisation in biological tissues, and (iii) approaches to detect unknown toxins or analogues of known toxins. Miniaturisation in combination with physico-chemical techniques appears to be a very efficient approach to detect low trace amounts of individual toxin analogues. In particular, the detection of azaspiracids and okadaic acid and analogues, using micro-filtration and on-line pre-concentration techniques, has shown to be useful for the characterisation of various algal and shellfish species. In the area of interactions of toxins with shellfish and mammalian systems, it is noted that several studies on biomarkers reveal either protein biomarkers of exposure to toxins or potential pathways of metabolism of the toxins themselves. A particular focus is given to recent findings in the areas of brevetoxin metabolism and biomarkers as well as azaspiracid localisation and metabolism. Finally, the detection of novel compounds is a particularly challenging area. The interest in this area has risen over the past years following cases of unexplained mouse toxicity such as the UK cockle toxicity and the French atypical toxicity in mussels and oysters from the Atlantic and Mediterranean coasts. Some attention is given to immuno-, functional and cellular bio-assays for the identification of bioactive agents in shellfish.
Durant les sept dernières années, les méthodes disponibles pour la détection des phycotoxines ont été abondamment revues dans de nombreux groupes internationaux d’expertises, tels que les consultations organisées par FAO/IOC/WHO et EFSA ainsi que dans de nombreux articles scientifiques de synthèse. Ces revues ont démontré que, vis-à-vis des systèmes de régulations officiels, les méthodes disponibles présentent des limites d’utilisation importantes. Soit elles ont un périmètre réduit et des limites de détection trop élevées, soit il y a un manque d’étalons, de matériaux de référence ou d’efforts de validation. La présente revue focalise sur les développements récents dans la détection de phycotoxines en recherche appliquée. Sans vouloir décrire de manière exhaustive tous les développements récents, la revue examine trois domaines d’intérêt pour les auteurs : (i) la détection de quantités ultra-traces de toxines, (ii) la métabolisation et la localisation des toxines dans des tissus biologiques, et (iii) les approches pour la détection de toxines non-répertoriées ou des analogues de toxines connues. La miniaturisation en combinaison avec les techniques physico-chimiques constitue apparemment une approche efficace pour la détection de faibles traces d’analogues individuels des toxines. En particulier, la micro-filtration et des techniques de pré-concentration en ligne se sont montrées utiles pour la détection des azaspiracides et des toxines du groupe de l’acide okadaïque dans la caractérisation de diverses espèces d’algues et de coquillages. Dans le domaine des interactions des toxines avec les coquillages et des systèmes vivants de mammifères, nous avons noté que plusieurs études sur les bio-marqueurs révèlent soit des marqueurs protéiniques d’exposition aux toxines, soit des marqueurs du métabolisme des toxines elles-mêmes. Un intérêt spécifique a été trouvé dans les résultats d’étude sur le métabolisme des brévétoxines et des azaspiracides. La détection des composés bioactifs non-répertoriés constitue un défi particulièrement difficile. Ce domaine a trouvé plus d’intérêt dû à plusieurs cas de toxicités inexpliquées dans le test souris telles que les toxicités observées dans les coques en provenance de Grande-Bretagne ou encore dans les moules et huîtres des côtes méditerranéennes et atlantiques françaises. Une attention particulière a été consacrée à l’identification d’agents bioactifs par les essais cellulaires ou fonctionnels ou basés sur la détection immuno-chimique.

Droits : 2010 SFET
http://archimer.ifremer.fr/doc/00019/12975/9949.pdf
http://archimer.ifremer.fr/doc/00019/12975/

Éditeur(s) : Centre Océanologique de Bretagne
Résumé : One of the criteria for selecting a shrimp of commercial interest in French Polynesia is the acceptability of artificial diet; such a criterion has been used to test Penaeus merguiensis.Experiments have been carried out in Centre Océanologique du Pacifique in Tahiti island where the water temperature range is 25-29°C, salinity 35 ppt, pH. 8.2, and photoperiod constant.Juveniles used in this study are hatched in CNEXO-COP at Vairao.It has been found that a 50-55% protein content diet gives a better growth performance. A carbohydrate such as starch appears more suitable than glucose or glucose plus starch in isonitrogenous purified diets.A vitamin mix rich in vitamin C, choline and inositol provides better results and a mineral mix with 3% magnesium reaches optimum. The major nutritional results for this species are applied to formulation of artificial diets.With the best diet, growth performances are normal: from 2.8 g to 9.0 g in 90 days, with about 60% survival rate at alow density, 20 animals/m² under strict control. But at another scale, in 400 m² graw-out tanks, growth was rather low even with an excellent Japanese diet containing 60% protein.Therefore, P. merguiensis does not appear to be a good candidate species for aquafarming in French Polynesia. [NOT CONTROLLED OCR]
Recueil des Travaux du Centre Océanologique de Bretagne (Centre Océanologique de Bretagne), 1979 , P. 705-714

Droits : Centre Océanologique de Bretagne
http://archimer.ifremer.fr/doc/1979/publication-5272.pdf
http://archimer.ifremer.fr/doc/00000/5272/

Éditeur(s) : Academic Affairs Library, University of North Carolina at Chapel Hill Academic Affairs Library, University of North Carolina at Chapel Hill ( [Chapel Hill, N.C.] )
Résumé : (Statement of Responsibility) written and revised from his own words by Samuel Moore.
(Original Version) Transcribed from the photocopy of: Detroit : Printed for the author, Mahommah Gardo Baquaqua, by Geo. E. Pomeroy & Co., Tribune office, 1854. 66 p. ; 22 cm. Biography of Mahommah G. Baquaqua : a native of Zoogoo, in the interior of Africa (a convert of Christianity), with a description of that part of the world, including the manners and customs of the inhabitants ... Mahommah's early life, his education, his capture and slavery in Western Africa and Brazil, his escape to the United States, from thence to Hayti, (the city of Port Au Prince,) his reception by the Baptist Missionary there, the Rev. W.L. Judd; his conversion to Christianity, Baptism, and return to this country, his views, objects and aim / written and revised from his own words by Samuel Moore, ESQ., late publisher of the "North of England Shipping Gazette," author of several popular works, and editor of sundry reform papers. Cover title: An interesting narrative : biography of Mahommah G. Baquaqua ...|"Prayer of the oppressed"--P. [66].
(Funding) Funding from the National Endowment for the Humanities supported the electronic publication of this title.
(System Details) Mode of access: Internet World Wide Web.
(System Details) System requirements: PC with modem or direct Internet connection; SGML viewer required for SGML files.
Title from electronic title page.
This electronic edition has been transcribed from a photocopy supplied by the North Carolina State University Library.
Includes information about Central Africa "their religious notions, form of government, laws, appearance of the country, buildings, agriculture, manufactures, shepherds and herdsmen, domestic animals, marriage ceremonials, funeral services, styles of dress, trade and commerce, modes of warfare, system of slavery, &c., &c."
This electronic edition is part of the UNC-CH digitization project's database, Documenting the American South. It is a part of the collection North American slave narratives.
Text transcribed by Apex Data Services, Inc. Text encoded by Apex Data Services, Inc., Elizabeth S. Wright and Natalia Smith.
Early Caribbean Digital Archive.
Africa
Africa
Brazil
Africa, Central
Africa, Central

Droits : See: http://docsouth.unc.edu/neh/baquaqua/menu.html
48112283
ocm48112283
http://ufdc.ufl.edu/AA00015610/00001

Éditeur(s) : ICCAT
Résumé : The present working document aims to list the main environmental databases (including in-situ observations, remote-sensing data and ocean models outputs), that are currently available on the Net and of interest in open-sea fisheries biology and ecology.
Ce document a pour objet de lister les principales bases de données environnementales (concernant les données in-situ, satellitaires et les sorties de modèles océaniques), qui sont actuellement disponibles sur la toile et d’intérêt pour l’écologie halieutique se rapportant aux ressources thonières.
El objetivo de este documento es presentar una relación de las principales bases de datos medioambientales (sobre datos in situ, vía satélite y valores de salida de los modelos oceánicos) que están disponibles actualmente en la red y que revisten interés para la ecología pesquera relacionada con los recursos atuneros.
Collective Volume of Scientific Papers (1021-5212) (ICCAT), 2005 , Vol. 58 , N. 5 , P. 1756-1760

Droits : ICCAT
http://archimer.ifremer.fr/doc/00194/30501/28911.pdf
http://archimer.ifremer.fr/doc/00194/30501/

Éditeur(s) : HAL CCSD
Résumé : International audience
Structure and evolution of networks have been areas of growing interest in recent years, especially with the emergence of Social Network Analysis (SNA) and its application in numerous fields. Researches on diffusion are focusing on network modeling for studying spreading phenomena. While the impact of network properties on spreading is now widely studied, involvement of network dynamicity is very little known. In this paper, we address the epidemiology context and study the consequences of network evolutions on spread of diseases. Experiments are conducted by comparing incidence curves obtained by evolution strategies applied on two generated and two real networks. Results are then analyzed by investigating network properties and discussed in order to explain how network evolution influences the spread. We present the MIDEN framework, an approach to measure impact of basic changes in network structure, and DynSpread, a 2D simulation tool designed to replay infections scenarios on evolving networks.
Database and Expert Systems Applications - 22nd International Conference, DEXA 2011, Toulouse, France, August 29 - September 2, 2011, Proceedings, Part II
Toulouse, France

hal-00614925
https://hal.archives-ouvertes.fr/hal-00614925
DOI : 10.1007/978-3-642-23091-2_49

Éditeur(s) : HAL CCSD Cnrs
Résumé : International audience
Tourism, Labour, Migration : Relationships and Human Mobility. -- A significant economic reality, the tourism market is at the origin of new and varied migratory paths in an increasingly restrictive international context. Established and emerging tourist destinations provide interesting laboratories in which to analyse the logic of the multiple forms of contemporary mobility. They constitute platforms that receive flows of tourists and workers from which new migratory paths are forged. At the meeting points between various flows, interrelationships, overlappings, and new filiations take shape.
Turismo, trabajo, migración : interrelaciones y lógicas de movilidad. -- Como realidad económica consolidada, el mercado turístico se encuentra en el centro de trayectorias migratorias diversas y renovadas en un contexto internacional cada vez más complejo. Las zonas turísticas -las clásicas y las emergentes- constituyen interesantes laboratorios a la hora de analizar la lógica de las movilidades contemporáneas y sus múltiples recomposiciones.Estos lugares, que reciben flujos de turistas y trabajadores, son una especie de plataformas que generan nuevas corrientes migratorias. En estos puntos de encuentro entre flujos diversos surgen interrelaciones, imbricaciones, filiaciones.
Réalité économique établie, le marché touristique est au coeur de trajectoires migratoires variées et renouvelées dans un contexte international de plus en plus contraignant. Les lieux touristiques, anciens et émergents, constituent d'intéressants laboratoires pour analyser les logiques des mobilités contemporaines et leurs recompositions multiformes. Ils constituent des plates-formes qui reçoivent des flux de touristes et de travailleurs à partir desquelles s'établissent de nouvelles trajectoires migratoires. De ces points de rencontre entre des flux variés où se dessinent des interrelations, des chevauchements, des filiations.
ISSN: 0765-0752

hal-01413567
https://hal.univ-antilles.fr/hal-01413567
https://hal.univ-antilles.fr/hal-01413567/document
https://hal.univ-antilles.fr/hal-01413567/file/2002%20Tourisme%2C%20travail%2C%20migration%20interrelation%20et%20logiques%20mobilitaires.pdf
DOI : 10.4000/remi.1676

Éditeur(s) : Caribbean Development Research Services Inc Caribbean Development Research Services Inc ( Barbados )
Résumé : The actually stated legislative preferences of Guyanese at this time are noteworthy since these speak to the activities that Guyanese wish to prevent. In this regard it is clear that Guyanese desire most to prevent “public sex” of any sort, but are especially concerned about relations between two or three men. Although there is a stated preference for the retention of the buggery law, there is little interest in having the state prevent private sex between adults (of any sex) if that were possible. This peculiarity suggests that Guyanese are perhaps really concerned about public manifestations of sexual orientation, as distinct from private manifestations and appear to believe that the changing of the laws would help to encourage these public manifestations. The juxtaposition of Guyanese support for decriminalisation (of homosexual acts) with their opinion on other major social issues does lend support to the suggestion that Guyanese are less committed to the retention of these laws than they are to issues like corporal punishment which also have a religious justification. This distance is significant, as is the finding in the survey that the position of a political party is not likely to affect its chances at the polls.

Droits : All rights reserved by the source institution.
http://ufdc.ufl.edu/AA00016151/00001

Éditeur(s) : Littoral 2004, Aberdeen, Scotland, UK, September 2004
Résumé : NAMIBIE (a french acronym for Integrated Multimedia Navigator Within Coastal Environment Data Bases) is a specific tool which first concept has been established by Ifremer and has been developped by an association between research in the field of coastal environment, innovation in the field of new information and communication technologies and services in the field of coastal integrated management and impact studies. The objectives of this tool are to facilitate research, direct access and display of relevant multimedia coastal integrated data and information according to an interactive, widely opened and playfull interface. The principles are based upon the fact that sustainable decision making needs an optimized unterstanding of coastal processes and better consultation between actors. In this purpose the development of the tool has considered that the end-user should and could be free to look after the data and the information he needs for a particular site or environment of interest and for a specific ICZM question according to easy navigation interfaces. That is why NAMIBIE concept is based upon : - a coherent 3D representation of the coasts (i.e. from catchement areas to continental shelf and deep sea), which considers a coherent DEM from land to sea and textural representation of the environment using satellite imagery textural displays, - a 3D navigator which allows the user to fly or dive over and within the coastal environment of interest, - a multimedia database (text, graphs, image, maps, geographic objects, modelling results...) specific to the territory of interest, - an interactive interface which helps in finding relevant information associated to specific questions. The technologies used include VRML data format, integration of standard GIS format (shp, grid, img) within the navigator, integration and display of modelling data. The production chain is realized in C++ and Java scripts allow dialogue between web pages and 3D windows. Applications are presented on the coasts of Languedoc Roussillon region (French Mediterranean border) in the framework of ICZM problematics

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00089/20055/17696.pdf
http://archimer.ifremer.fr/doc/00089/20055/

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : L’organisation et la gestion des espaces publics en milieu urbain sont au centre des préoccupations de la puissance publique. Cet intérêt est lié dans les pays en développement aux nombreux dysfonctionnements recensés dans la ville. Ces difficultés sont entretenues par la démographie galopante, l’urbanisation informelle et à l’accroissement des activités industrielles, commerciales entre autres. À Dakar, la question de la mobilité urbaine est exacerbée par les puissants mouvements pendulaires entre la ville centrale et la périphérie amplifiés par les stationnements anarchiques et par l’inorganisation des modes de transports urbains.Le type d’espace public choisi pour cet article est une gare routière située au cœur du Plateau de Dakar : Petersen. Elle apparaît comme l’une des plus importantes gares routières du pays, surtout en matière de fréquentation avec plus de 50 000 personnes par jour. Le mode de gestion appliqué ici est la concession, une convention par laquelle la puissance publique confie la gestion de l’équipement à la SAGES une structure privée prenant en charge les intérêts parfois très contradictoires des différents acteurs.
The organization and management of public spaces in urban areas is a central concern of public authorities. This interest is linked in developing countries with numerous shortcomings identified in the city. These difficulties sustained by massive population growth, urbanization informal, and increased industrial activities, commercial and others. In Dakar, the question of urban mobility is exacerbated by the significant commuting between the city center and the periphery that are amplified by the chaotic parking lots and the disorganization of urban transport modes.The type of public space chosen for this article is a bus station in the heart of the Plateau de Dakar: Petersen. It appears as one of the largest bus stations in the country, especially in terms of attendance with over 50,000 people per day.The management method applied here is the concession, an agreement by which the public entrusts the management of equipment at the SAGES, a private organization that supports some very conflicting interests of different actors.
Sénégal
Dakar

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.7858
http://journals.openedition.org/etudescaribeennes/7858

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is only expressed in radial glial progenitors in the brain of fish and (ii) it is exquisitely sensitive to estrogens. Based on these properties, we demonstrate that natural or synthetic hormones (alone or in binary mixture), including androgens or progestagens, and industrial chemicals induce a concentration-dependent GFP expression in radial glial progenitors. As GFP expression can be quantified by in vivo imaging, this model presents a very powerful tool to screen and characterize compounds potentially acting as estrogen mimics either directly or after metabolization by the zebrafish embryo. This study also shows that radial glial cells that act as stem cells are direct targets for a large panel of endocrine disruptors, calling for more attention regarding the impact of environmental estrogens and/or certain pharmaceuticals on brain development. Altogether these data identify this in vivo bioassay as an interesting alternative to detect estrogen mimics in hazard and risk assessment perspective.
ISSN: 1932-6203

hal-00877371
https://hal.archives-ouvertes.fr/hal-00877371
https://hal.archives-ouvertes.fr/hal-00877371/document
https://hal.archives-ouvertes.fr/hal-00877371/file/Screening_Estrogenic_Activities-accepted.pdf
DOI : 10.1371/journal.pone.0036069

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This work relates to the characterisation of the predominant gill protein of the white clam, Codakia orbicularis (Linné, 1758), which harbours endosymbiotic sulphur-oxidising chemoautotrophic bacteria. Total RNA was extracted from the clam to perform 3'rapid amplification of cDNA ends (3'RACE) using degenerate oligonucleotides prepared from a partial sequence of a predominant protein of about 14kDa, termed codakine. The partial peptide sequence was obtained by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and Edman degradation. Clones isolated from the cDNA library and containing the gene of interest were used in polymerase chain reaction (PCR). The PCR and RACE-PCR products were sequenced to determine the entire coding DNA sequence of codakine. BLAST analysis revealed about 23% to 29% sequence identity between codakine and various animal C-type lectins that are often involved in symbiosis and immune defences. Codakine also contains the motifs and domains of Ca(2+)-dependent C-type lectins, and in particular the tripeptide EPN motif frequently found in mannose-binding lectins (MBLs). Analysis of the protein by affinity chromatography on a mannose-agarose column is consistent with the findings that codakine is a dimeric Ca(2+)-dependent MBL of about 29kDa. Based on the present results, it is hypothesised that this novel C. orbicularis gill protein is involved in the recognition of symbiotic and pathogenic bacteria.
ISSN: 1050-4648

hal-00746015
https://hal.univ-antilles.fr/hal-00746015
DOI : 10.1016/j.fsi.2006.06.013
PUBMED : 17169576

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
A novel antimicrobial peptide, named Bicarinalin, has been isolated from the venom of the ant Tetramorium bicarinatum. Its amino acid sequence has been determined by de novo sequencing using mass spectrometry and by Edman degradation. Bicarinalin contained 20 amino acid residues and was C-terminally amidated as the majority of antimicrobial peptides isolated to date from insect venoms. Interestingly, this peptide had a linear structure and exhibited no meaningful similarity with any known peptides. Antibacterial activities against Staphylococcus aureus and S. xylosus strains were evaluated using a synthetic replicate. Bicarinalin had a potent and broad antibacterial activity of the same magnitude as Melittin and other hymenopteran antimicrobial peptides such as Pilosulin or Defensin. Moreover, this antimicrobial peptide has a weak hemolytic activity compared to Melittin on erythrocytes, suggesting potential for development into an anti-infective agent for use against emerging antibiotic-resistant pathogens.
ISSN: 0196-9781

hal-00996401
https://hal.archives-ouvertes.fr/hal-00996401
DOI : 10.1016/j.peptides.2012.08.018
PUBMED : 22960382

Éditeur(s) : Longman, Hurst, Rees, Orme & Brown, Paternoster Row, Longman, Hurst, Rees, Orme & Brown, Paternoster Row, ( London )
Résumé : Hand colored ca. 2000. Plate from A general collection of the best and most interesting voyages and travels in all parts of the world / by John Pinkerton. -- London : Longman, Hurst, Rees, Orms, & Brown, 1808-14. 17 v.
Digital image.2005.600 ppi, 4952 x 6400 pixels, 92,854 kb rgb tif. Prints. Box 39.
Roseau (Dominica)

Droits : All rights reserved by the source institution.
2004-319-1
2004-425-1

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
This special issue in honour of the late Olivier Jaoul brings together contributions from experimental and theoretical mineralogy, the area of most of Olivier's own work, focused for the most part on the Earth's mantle. The volume is divided into three sections; diffusion, deformation and seismic properties. New technological developments have often had a strong impact on research in this area, as again shown by Olivier's constant search to improve the resolution of the short diffusion profiles typical of major cations in mantle silicates. In the section on diffusion the impact of improved computer performance for modelling diffusion and point defect configurations on one hand, and high pressure experimental techniques on the other hand, highlight the continued development in this area. The section on deformation deals with wide range of subjects, including the deformation of olivine and quartz and the relation between deformation and diffusion, both subjects close to Olivier's personal interests. This illustrates the new possibilities to undertake deformation experiments at mantle pressures and temperatures, as well as improvement in high-fidelity viscoelastic measurements at high temperature. In the last section on seismic properties we discover theoretical developments on predicting properties near the Earth's surface and a new experimental application, which allows the determination of sound velocity at very high pressures with implications for the Earth's inner core.
ISSN: 0031-9201

hal-00475657
https://hal.archives-ouvertes.fr/hal-00475657
DOI : 10.1016/j.pepi.2008.09.009