Éditeur(s) : ESA Publication
Résumé : Satellite remote sensing has emerged as an essential and necessary observing system to acquire global information about the state of the ocean. Complemented with in situ observing networks, the ultimate goals are to be able to make accurate estimates of selected key sets of geophysical variables, with the intention of either making operational predictions across time and spatial boundaries, or advancing fundamental knowledge through development of empirical relationships and theoretical models. For satellite oceanography, improvements are then constantly being sought in our understandings of the geophysical processes, the sensor physics, the electromagnetic and microwave properties and interactions at the complex air-sea interface. Challenges appear as unlimited as the variety of sea surface dynamics and boundary layer meteorological conditions with their broad range of spatial and temporal scales across the globe. To face these challenges, numerous efforts took places over the passed decade to build an ever-increasing quality, quantity, duration and integration of ocean observations. In parallel, simulation capabilities largely improved. All these efforts are then all critically calling for improved methodologies to better structure the wealth of information that is made readily accessible. This latter aspect is a very demanding new component for future multidisciplinary scientific research. Major innovations to consolidate sensor data repositories, to automate tailored queries, to extract, reveal and quantify relationships will then closely associate computer science developments and applied statistics with comprehensive theoretical and experimental thematic studies.
Proceedings of OceanObs'09: Sustained Ocean Observations and Information for Society (ESA Publication), 2010

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00029/14046/11241.pdf
DOI:10.5270/OceanObs09.pp.12
http://archimer.ifremer.fr/doc/00029/14046/

Éditeur(s) : HAL CCSD
Résumé : In SW Yukon – SE Alaska, the boundary between the Pacific and North America plates is characterized by a syntaxis at the transition between the Aleutian subduction to the W and the Fairweather – Queen Charlotte strike-slip faults to the SE. The relative motion is oblique to the main fault structures, and the area is marked by the Yakutat block collision. From the Chugach – Saint Elias mountains in the plate boundary zone (up to 6 000 m high) to the intraplate strike-slip faults, markers of the present-day deformation give information on its partition in the system.During my PhD, I first measure surface deformation using a dense GPS network, deployed up to 500 km inland the North America plate. After precise processing and corrections of transient effects in the area (postseismic and glacial isostatic rebound), a new residual velocity field is produced for the syntaxis area, from which I derive strain rates. Those data allow me to quantify the fault slip rates for Fairweather and southern Denali strike-slip faults, and to characterize a bi-modal deformation pattern: Along the plate boundary, the deformation is localized on large-scale structures (accretionary prism to the W, Fairweather to the E); In the syntaxis area, strain rates are the highest and the GPS data shows a diffuse intraplate deformation, similar to an indentor pattern. The Yakutat block seems to strongly drive the North America plate deformation.This indentor pattern induces strong lateral variations on the large intraplate faults: the Denali – Totschunda – Duke River system. In a second part, I realize a regional geomorphological study to characterize the role and slip rate of those faults. From very high-resolution Digital Elevation Models (~ 1 m), a detailed cartography is done. On the basis of fieldwork observations, I measure offsets of fluvial and glacial markers, which are sampled for dating. A dextral cumulative deformation is highlighted on the northern Denali Fault, where as all southern Denali is marked by vertical deformation. This study allows me to quantify new slip rates for the system Denali – Totschunda – Duke River, and to show the leading role of the Totschunda (~ 14 mm/a) and Duke River (~ 6 mm/a) faults, contrary to the Denali Fault (~ 1 mm/a) North of the syntaxis.The new tectonic model for the Yakutat collision provides an important case study for the understanding of indentor systems. The concomitance of a rigid-block deformation (to the West) and diffuse deformation (to the East), as well as the near-zero slip rate on the lithospheric-scale southern Denali Fault highlight the major control of boundary conditions and the structural heritage on the orogen deformation.
Au SO Yukon – SE Alaska, la frontière entre les plaques Pacifique et Nord-Amérique est marquée par une syntaxe à la transition entre la subduction des Aléoutiennes à l’O et le décrochement de Fairweather – Queen Charlotte au SE. Le mouvement relatif est oblique et la région est marquée par la collision du bloc Yakutat. De la chaine des Chugach – Saint Elias en frontière de plaque (jusqu’à 6 000 m d’altitude) aux grands décrochements intraplaque, les marqueurs de la déformation actuelle apportent des informations sur sa partition dans ce système.Au cours de cette thèse, je m’intéresse dans un premier temps à mesurer la déformation de surface à l’aide d’un réseau GPS dense, déployé jusqu’à 500 km à l’intérieur de la plaque Nord-Amérique. Après un travail minutieux de traitement des données et de correction des effets transitoires (rebond post-glaciaire et post-sismique), un champ de vitesses résiduelles robuste et inédit est produit au niveau de la syntaxe, dont je dérive des taux de déformation. Ces données me permettent de quantifier les vitesses de glissement les failles décrochantes de Fairweather et Denali au Sud, et également de caractériser une déformation bimodale : En frontière de plaques, la déformation est localisée sur les grandes structures (prisme d’accrétion à l’O, Fairweather à l’E) ; Au niveau de la syntaxe, les taux de déformation sont les plus importants et les données GPS mettent en évidence une déformation intraplaque diffuse, similaire à un champ attendu à l’aplomb d’un indenteur. Le bloc Yakutat semble donc contrôler fortement la déformation de la plaque Nord-Amérique.Ce champ de déformation induit des variations latérales fortes sur les grandes failles intraplaque : le système Denali-Totschunda-Duke River. Dans une seconde partie, je réalise une étude géomorphologique régionale pour caractériser le rôle et la vitesse de ces failles. À partir de Modèles Numériques de Terrain très haute résolution (~ 1 m), une cartographie de détail est réalisée. Puis une mission de terrain me permet de mesurer des décalages sur des marqueurs fluviatiles et glaciaires et collecter des échantillons pour les dater. Je mets en évidence une déformation cumulée dextre sur le segment Nord de la faille de Denali, alors que toute la partie Sud déforme verticalement la surface. Cette étude me permet de quantifier de nouvelles vitesses de failles sur le système Denali-Totschunda-Duke River, et de montrer le rôle prépondérant des failles de Totschunda (~ 14 mm/a) et Duke River (~ 6 mm/a) contrairement à la faille de Denali (~ 1 mm/a) au Nord de la syntaxe.Le nouveau modèle cinématique proposé pour la région de collision Yakutat permet d’apporter un nouvel exemple à la compréhension des systèmes d’indenteur. La concomitance d’une déformation de blocs (à l’Ouest) et diffuse (à l’Est), ainsi que l’absence de déformation sur la faille lithosphérique de Denali Sud met en évidence le contrôle majeur des conditions aux limites et de l’héritage structural dans la déformation des orogènes.
https://hal.archives-ouvertes.fr/tel-01241688

tel-01241688
https://hal.archives-ouvertes.fr/tel-01241688
https://hal.archives-ouvertes.fr/tel-01241688/document
https://hal.archives-ouvertes.fr/tel-01241688/file/manuscrit_anais_v2_optimise.pdf

Éditeur(s) : HAL CCSD
Résumé : International audience
Mylonite bodies are exhumed extensions at depth of shallow structural level brittle faults. They are characterised by intense strain localisation involving large volumes of middle to lower continental crust. The analysis of shear zone geometry and microstructures is a useful tool to decipher deformation kinematics, though finite strain estimation is still relatively qualitative. Timing of the deformation has also been the focus of numerous studies using the complete spectrum of geochronometers. However, only rare examples provide geochronological data that can be unambiguously interpreted and cooling, recrystallisation and neocrystallisation are difficult to tell from each other. Thus, time-scales over which major mylonite zones develop and remain active under ductile conditions as well as their strain rate often remain poorly documented. We investigated two sections across the South-Armorican Shear Zone (SASZ), a crustal-scale pluri-km thick dextral shear zone active during a single tectonic event of late-Variscan age and associated with syntectonic granite emplacement.. Finite strain profiles on these cross-sections, quantified from average Quartz grain-size in 34 samples, show a strong deformation partitioning towards the center of the SASZ, with a decrease, for each section, from 150µm in slightly deformed zones to less than 7-5 µm in the core of the ultramylonite. Furthermore, toward the core of the SASZ, development of a penetrative shear band network progressively eliminates lenses of less deformed rocks and results in homogenisation of the Quartz grain sizes. In parallel, we performed in-situ UV-laser Ar/Ar dating on the fabric-forming white micas. White micas population can be decomposed into inherited muscovites carried by the folation and newly-formed, syn-tectonic substituted phengites located along the shear bands yielding 2 age groups for each sample. Along the profiles, the difference between these two ages evolves from 10-15 Ma in weakly deformed domains to zero toward the SASZ core. In addition, mylonite-forming phengites yielded the same age irrespectively of their position on the section or of the rock strain.. On the regional point of view, this study brings deformation-ages for the late-orogenic evolution of the South Armorican domain. Strain accumulated along the SASZ in a time-span extending to 300-298 Ma, i.e. contemporaneously with the activity of nearby major extensional shear zones. These results support a new model of crustal-scale shear zone activity, where the whole body of the shear zone is active throughout its history (defined as the largest age difference through the section), i.e. the actively deforming zone does not get progressively narrower. The strain distribution nevertheless evolves with time, with an increasingly large fraction partitioned in the ultramylonitic core.
EGU General Assembly
Vienne, Austria

insu-00839320
https://hal-insu.archives-ouvertes.fr/insu-00839320
BIBCODE : 2010EGUGA..12.9881A

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Upper-mantle flow beneath the South Pacific is investigated by analysing shear wave splitting parameters at eight permanent long-period and broad-band seismic stations and 10 broad-band stations deployed in French Polynesia from 2001 to 2005 in the framework of the Polynesian Lithosphere and Upper Mantle Experiment (PLUME). Despite the small number of eventsand the rather poor backazimuthal coverage due to the geographical distribution of the natural seismicity, upper-mantle seismic anisotropy has been detected at all stations except at Tahiti where two permanent stations with 15 yr of data show an apparent isotropy. The median value of fast polarization azimuths (N67.5°W) is parallel to the present Pacific absolute platemotion direction in French Polynesia (APM: N67°W). This suggests that the observed SKS fast polarization directions result mainly from olivine crystal preferred orientations produced by deformation in the sublithospheric mantle due to viscous entrainment by the moving Pacific Plate and preserved in the lithosphere as the plate cools. However, analysis of individualmeasurements highlights variations of splitting parameters with event backazimuth that imply an actual upper-mantle structure more complex than a single anisotropic layer with horizontal fast axis. A forward approach shows that a two-layer structure of anisotropy beneath French Polynesia better explains the splitting observations than a single anisotropic layer. Second ordervariations in the measurements may also indicate the presence of small-scale lateral heterogeneities. The influence of plumes or fracture zones within the studied area does not appear to dominate the large-scale anisotropy pattern but may explain these second-order splitting variations across the network.
ISSN: 0956-540X

hal-01249275
https://hal.archives-ouvertes.fr/hal-01249275
https://hal.archives-ouvertes.fr/hal-01249275/document
https://hal.archives-ouvertes.fr/hal-01249275/file/GJI2007SKS.pdf
DOI : 10.1111/j.1365-246X.2007.03475.x

Éditeur(s) : HAL CCSD American Society for Microbiology
Résumé : International audience
Toxoplasmosis is a life-threatening infection in immunocompromised patients (ICPs). The definite diagnosis relies on parasite DNA detection, but the incidence and burden of disease are ill-known in HIV-negative patients. A three-year retrospective study was conducted in 15 reference laboratories from the network of the French National Reference Center for Toxoplasmosis, to record the frequency of Toxoplasma DNA detection in ICPs, to review the molecular methods used for diagnosis and the prevention measures implemented in transplant patients. During the study period, out of 31,640 PCR performed in ICPs, 610 were positive (323 patients). Blood (n=337), cerebrospinal fluid (n=101) and aqueous humor (n=100) samples were more frequently positive. Chemoprophylaxis schemes in transplant patients differed between centers. PCR follow-up of allogeneic hematopoietic stem-cell transplant (allo-HSCT) patients was implemented in 8/15 centers. Data from 180 patients (13 centers) were further analyzed regarding clinical setting and outcome. Only 68/180 (38%) patients were HIV+; the remaining 62% consisted in 72 HSCT, 14 solid-organ transplants, and 26 miscellaneous immunodeficiencies. Cerebral toxoplasmosis and disseminated toxoplasmosis were most frequently observed in HIV and transplant patients, respectively. Of 72 allo-HSCT patients with a positive PCR, 23 were asymptomatic; all were diagnosed in centers performing systematic blood PCR follow-up, and received specific treatment. Overall survival of allo-HSCT patients at two months was better in centers with PCR follow-up than in other centers (p<0.01). This study provides updated data on the frequency of toxoplasmosis in HIV-negative ICPs and suggests that regular PCR follow-up of allo-HSCT patients could guide pre-emptive treatment and improve outcome.
ISSN: 0095-1137

hal-01134189
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01134189
DOI : 10.1128/JCM.03282-14
PUBMED : 25762774

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Clin Microbiol Infect 2012; 18 (Suppl. 4): 4043 Abstract In order to study complex microbial communities and their associated mobile genetic elements, such as the human gut microbiome, evolutionists could explore their genetic diversity with shared sequence networks. In particular, the detection of remarkable structures in gene networks of the gut microbiome could serve to identify important functions within the community, and would ease comparison of data sets from microbiomes of various sources (human, ape, mouse etc.) in a single analysis.
ISSN: 1198-743X

hal-01544804
https://hal.archives-ouvertes.fr/hal-01544804
DOI : 10.1111/j.1469-0691.2012.03856.x

Éditeur(s) : HAL CCSD Hindawi Publishing Corporation
Résumé : During the 1982-1984 bradyseismic crises in the Campi Flegrei area (Italy), the University of Wisconsin deployed a network of seismological stations to record local earthquakes. In order to analyse the potential of the recorded data in terms of tomographic imaging, a blind test was recently set up and carried out in the framework of a research project. A model representing a hypothetical 3D structure of the area containing the Campi Flegrei caldera was also set up, and a synthetic dataset of time arrivals was in turn computed. The synthetic dataset consists of several thousand P- and S-time arrivals, computed at about fourteen stations. The tomographic inversion was performed by four independent teams using different methods. The teams had no knowledge of either the input velocity model or the earthquake hypocenters used to create the synthetic dataset. The results obtained by the different groups were compared and analysed in light of the true model. This work provides a thorough analysis of the earthquake tomography potential of the dataset recording the seismic activity at Campi Flegrei in the 1982-1984 period. It shows that all the tested earthquake tomography methods provide reliable low-resolution images of the background velocity field of the Campi Flegrei area, but with some differences. However, none of them succeeds in detecting the hypothetical structure details (i.e. with a size smaller than about 1.5-2 km), such as a magmatic chamber 4 km deep and especially the smaller, isolated bodies, which represent possible magmatic chimneys and intrusions.
ISSN: 1687-885X

hal-00795584
https://hal.archives-ouvertes.fr/hal-00795584
DOI : 10.1155/2012/505286

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Alkali feldspar thermochronologic modeling with the 40Ar/39Ar method has generated marked advances in knowledge of the mechanisms for argon diffusion in feldspars. While the goal in many cases has been to extrapolate the observed and modeled argon behavior in feldspars to natural geological settings, scientific debate surrounding the true feasibility of such extrapolations and indeed, the validity of thermochronologic modeling in itself, have provided much impetus to improve laboratory techniques to test, and increase basic understanding of, argon diffusion. Two cornerstones for the debate over the feasibility of alkali feldspar thermochronology for modeling natural, geologic processes have been: 1. is volume diffusion the main mechanism for argon movement in feldspars? and 2. if volume diffusion is a viable mechanism, does argon then reside in discrete ‘domains' within the feldspar lattice? We describe a study of alkali feldspars from a profile through a well-controlled brittle fault zone in western Norway; the feldspars document argon loss during deformation and strongly suggest the existence of argon ‘domains' within the feldspars, at least during laboratory step heating. The progressive change in the character of argon diffusion is recognizable in the logr/ro diffusion data from the feldspars and is mimicked by physical changes observed optically in the feldspars through progressive degrees of brittle deformation. Modeling results indicate a reduction in size of the biggest domains and the appearance of smaller domains during the strongest stages of deformation. Whether or not this reveals the existence and the transformation of the domain structure in naturo is difficult to prove from our data alone, but interestingly, this behaviour corresponds directly to the physical (optical) appearance of more intense crack networks and subgrains in progressively more brecciated feldspars. Because the thermochronologic histories derived from modeling the feldspar data conform very well to the known tectonic history of the area, the feldspars appear to have successfully retained physical (optical and isotopic) records of episodic tectonic processes operating from ductile through lowtemperature brittle regimes in rocks with a Caledonian history overprinted by several later (younger) geologic events. However, because the ‘cold' brecciation is the last tectonothermal event recorded by these rocks, it is impossible to truly test for the existence of diffusion domains in naturo. Argon loss appears to have been effective only in the most highly brecciated (deformed) samples where the combination of the connected crack network, increased fluid flow and higher temperatures enhanced diffusion via fast diffusion pathways and thus, volume diffusion from the lattice. Only minor argon loss occurred in zones of lower brittle strain, although some development of cracks and brittle features is evident. Independent of the existence of diffusion domains, this study highlights the possible pitfalls when cooling histories are deduced from brecciated feldspars in which age and diffusion charateristics have been decoupled: while the geochronological memory has survived and is identical to that of nonbrecciated feldspars (suggesting no loss and minor effects of deformation), the diffusion characteristics have been completely transposed by brecciation and the appearance of new domains. Modeling feldspars with these latter characteristics would effectively utilise a new feldspar diffusion structure with an ‘old' (relict) age memory.
ISSN: 0016-7037

hal-00198283
https://hal.archives-ouvertes.fr/hal-00198283
https://hal.archives-ouvertes.fr/hal-00198283/document
https://hal.archives-ouvertes.fr/hal-00198283/file/KsparBreccia_Arnaud_Eide_GCA_2000.pdf

Éditeur(s) : HAL CCSD
Résumé : The heterogeneous nature and sometimes karstified carbonate environments has a direct impact on many environmental issues, such as coastal aquifers affected by saltwater intrusion. At the south of the island of Mallorca (Spain), the Llucmajor carbonate platform offers a privileged site for the study of such intrusions including the experimental site of Campos who meets the intrusion at shallow depth. The characterization of heterogeneous properties passes through a preliminary description of the properties of carbonate reservoirs, including those of the porosity. According to the wide range of sizes of heterogeneities from micrometer to hundreds of meters, the use of multiscale methods is required. This thesis focused on the determination of multiscale porosities from the microporosity to karstic porosity, and of relationships between observation scale changes of these properties. At the micron scale, high-resolution X-ray microtomography allows to extract the microporosity and the microporous network connectivity. At lower resolution (mm), X-ray tomography is also used to study the micro- and macro-porous network at the core scale which is already allocated to number of observations and measurements, including petrophysical. At the borehole scale, the wall images are used to identify the dissolved zones from centimeter macropores to plurimetric karstic cavities. At the larger scale, surface geophysics study the lateral extension of the karsts and heterogeneities. Finally, the porous structure of the studied site is integrated with its wide range of scales into the regional geology of the Llucmajor platform. Thus, the hydrogeophysical observatory set up on the site of Campos to monitor the spreading of salt water in the aquifer is integrated in its geological and petrophysical context, in order to refine the interpretation of its variations of salinity measurements during the time.
La nature hétérogène et parfois karstifiée des milieux carbonatés a un impact direct sur nombre de problématiques environnementales, comme celle des aquifères côtiers affectés par une intrusion d'eau salée. Au sud de l'ile de Majorque (Baléares, Espagne), la plate-forme carbonatée de Llucmajor offre un site privilégié pour l'étude de telles intrusions notamment avec le site expérimental de Campos, qui rencontre l'intrusion à faible profondeur. La caractérisation des propriétés hétérogènes du réservoir passe par une description préalable des propriétés des réservoirs carbonatés et notamment celle de la porosité. Au regard de la large gamme d'échelles d'hétérogénéités allant du micromètre à la centaine de mètre, l'utilisation de méthodes multi-échelles est nécessaire. Ce travail de thèse a porté sur la caractérisation multi-échelle de la porosité, allant de la microporosité à la porosité karstique, et l'établissement de relations entre les changements d'échelles d'observation de ces propriétés. A très petite échelle, la microtomographie haute-résolution à rayons X extrait à l'échelle du micron la microporosité et la connectivité des réseaux microporeux. A plus basse fréquence (celle du mm), la tomographie est également utilisée afin d'étudier le réseau micro- et macroporeux à l'échelle des carottes, à laquelle sont réalisées nombre d'observations et de mesures, notamment pétrophysiques. A l'échelle du puits, les images de paroi permettent d'identifier les zones de dissolution allant des macropores centimétriques aux cavités karstiques plurimétriques. A plus grande échelle, la géophysique de surface permet d'étudier l'extension latérale de ces karsts et hétérogénéités. Enfin, la structure poreuse du site étudié sur cette vaste gamme d'échelles est intégrée à la géologie régionale de la plate-forme de Llucmajor. Ainsi, l'observatoire installé sur le site pour surveiller la propagation de l'eau salée dans l'aquifère a pu être replacé dans son contexte géologique et pétrophysique, afin d'affiner l'interprétation de ses mesures de variations de salinité au cours du temps.
https://tel.archives-ouvertes.fr/tel-00633488

tel-00633488
https://tel.archives-ouvertes.fr/tel-00633488
https://tel.archives-ouvertes.fr/tel-00633488/document
https://tel.archives-ouvertes.fr/tel-00633488/file/TheseHebert.pdf

Éditeur(s) : HAL CCSD Techno-Press
Résumé : Fractures and faults riddle the Earth’s crust on all scales, and the deformation associated with them is presumed to have had significant effects on its petrological and structural evolution. However, despite the abundance of directly observable earthquake activity, unequivocal evidence for seismic slip rates along ancient faults is rare and usually related to frictional melting and the formation of pseudotachylites. We report novel microstructures from garnet crystals in the immediate vicinity of seismic slip planes that transected lower crustal granulites during intermediate-depth earthquakes in the Bergen Arcs area, western Norway, some 420 million years ago. Seismic loading caused massive dislocation formations and fragmentation of wall rock garnets. Microfracturing and the injection of sulfide melts occurred during an early stage of loading. Subsequent dilation caused pervasive transport of fluids into the garnets along a network of microfractures, dislocations, and subgrain and grain boundaries, leading to the growth of abundant mineral inclusions inside the fragmented garnets. Recrystallization by grain boundary migration closed most of the pores and fractures generated by the seismic event. This wall rock alteration represents the initial stages of an earthquake-triggered metamorphic transformation process that ultimately led to reworking of the lower crust on a regional scale.
ISSN: 2287-528X

hal-01553309
https://hal.archives-ouvertes.fr/hal-01553309
https://hal.archives-ouvertes.fr/hal-01553309/document
https://hal.archives-ouvertes.fr/hal-01553309/file/austrheim2017.pdf
DOI : 10.1126/sciadv.1602067

Éditeur(s) : HAL CCSD
Résumé : In this paper we introduce k-laminar graphs a new class of graphs which extends the idea of Asteroidal triple free graphs. Indeed a graph is k-laminar if it admits a diametral path that is k-dominating. This bio-inspired class of graphs was motivated by a biological application dealing with sequence similarity networks of reads (called hereafter read networks for short). We briefly develop the context of the biological application in which this graph class appeared and then we consider the relationships of this new graph class among known graph classes and then we study its recognition problem. For the recognition of k-laminar graphs, we develop polynomial algorithms when k is fixed. For k=1, our algorithm improves a Deogun and Krastch's algorithm (1999). We finish by an NP-completeness result when k is unbounded.
https://hal.inria.fr/hal-01282715

hal-01282715
https://hal.inria.fr/hal-01282715
ARXIV : 1603.01179

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Upper mantle anisotropy beneath the African IRIS and Geoscope stations is investigated through the measurements of splitting of teleseismic shear waves such as SKS, SKKS and PKS phases. Seismic anisotropy data are interesting on their own as a measure of upper mantle active or frozen deformation beneath a given station, but each station is of potential interest since it can be used to retrieve source-side seismic anisotropy at remote sites if one is able to perform station-side anisotropy correction. We performed systematic investigations of teleseismic shear wave splitting at 15 stations from the IRIS and Geoscope global seismic networks, which are located on both the oceanic and the continental parts of the African plate. Anisotropy is generally well observed at continental stations. The patterns we present generally show much more complexity than the results previously published from smaller data sets. Despite this complexity, the splitting parameters generally appear in several places to contain a signature of the regional geodynamic setting (rift structures, Archaean craton, Pan-African belt), although a deeper source of anisotropy (asthenospheric) may be present. At the oceanic stations, anisotropy measurements are much more difficult to perform because the signal is generally of poor quality. MSEY, in the Seychelles (Indian ocean), is the exception and displays a clear correlation of the azimuth of the fast split shear wave with the trend of the absolute plate motion, as defined by hotspot tracks.
ISSN: 0956-540X

hal-01380389
https://hal.archives-ouvertes.fr/hal-01380389
https://hal.archives-ouvertes.fr/hal-01380389/document
https://hal.archives-ouvertes.fr/hal-01380389/file/Barruol_SKS_afric_GJI2001.pdf
DOI : 10.1046/j.0956-540x.2001.01481.x

Éditeur(s) : HAL CCSD Springer
Résumé : International audience
he search for frequent conceptual links (FCL) is a new network clustering approach that exploits both the network structure and the node properties. While recent works have been focused on the optimisation of the FCL extraction, no study has been conducted on the matching or the intersections between the conceptual links and the classical clustering approach which consists in extracting communities. In this paper, we focus on these two approaches. Our objective is to evaluate the possible relationships existing between FCL and communities to understand how the patterns obtained by each kind of methods may match as well as the useful knowledge resulting from the intersections of these two kinds of knowledge. For this purpose, we propose a set of original measures, based on the notion of homogeneity, assessing the level of shared information between these patterns when they are extracted from the same dataset. The measures are applied on three datasets and demonstrate the importance of considering simultaneously various kinds of knowledge and their intersections.
ISSN: 1869-5450

hal-01312313
https://hal.archives-ouvertes.fr/hal-01312313
DOI : 10.1007/s13278-014-0197-1

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
A hallmark of living systems is the management and the storage of information through genetic and epigenetic mechanisms. Although the notion of epigenetics was originally given to any regulation beyond DNA sequence, it has often been restricted to chromatin modifications, supposed to behave as cis-markers, specifying the sets of genes to be expressed or repressed. This definition does not take into account the initial view of epigenetics, based on nonlinear interaction networks whose "attractors" can remain stable without need for any chromatin mark. In addition, most chromatin modifications are the steady state resultants of highly dynamic modification and de-modification activities and, as such, seem poorly appropriate to work as long-term memory keepers. Instead, the basic support of epigenetic memory could remain the attractors, to which chromatin modifications belong as do many other components. The influence of chromatin modifications in memory is highly questionable when envisioned as static structural marks, but can be recovered under the dynamic circuitry perspective, thanks to their self-templating properties. Beside their standard repressive or permissive functions, chromatin modifications can also influence transcription in multiple ways such as: (1) by randomizing or inversely stabilizing gene expression, (2) by mediating cooperativity between pioneer and secondary transcription factors, and (3) in the hysteresis and the ultrasensitivity of gene expression switches, allowing the cells to take unambiguous transcriptional decisions.
ISSN: 1420-682X

hal-01063617
https://hal.archives-ouvertes.fr/hal-01063617
DOI : 10.1007/s00018-012-0923-7
PUBMED : 22331281

Éditeur(s) : HAL CCSD American Chemical Society
Résumé : Three new monoterpene indole alkaloids (13) have been isolated from the bark of Geissospermum laeve-, together with the known alkaloids (-)-leuconolam (4), geissolosimine (5), and geissospermine (6). The structures of 1-3 were elucidated by analysis of their HRMS and NMR spectroscopic data. The absolute configuration of geissolaevine (I). was deduced from the comparison of experimental and theoretically calculated ECD spectra. The isolation workflow was guided by a molecular networking-based dereplication strategy using an in-house database of monoterpene indole alkaloids. In addition, five known compounds previously undescribed in the Geissospermum genus were dereplicated from the G. laeve alkaloid extract network and were assigned with various levels of identification confidence. The antiparasitic activities against Plasmodium falciparum and Leishmania donovani as well as the Ortotoxic activity against the MRC-5 cell line were determined for compounds 1-5.
ISSN: 0163-3864

hal-01605065
https://hal.archives-ouvertes.fr/hal-01605065
DOI : 10.1021/acs.jnatprod.6b01013
PRODINRA : 402605
PUBMED : 28282127

Résumé : Les fourmis sont des organismes cibles appropriés pour les études environnementales. Au cours de notre étude, nous nous sommes focalisés sur les fourmis de la litière via l'application de deux méthodes de récolte complémentaires selon le protocole all (ants of leaf litter). Dans les forêts naturelles de Guyane française, l'hétérogénéité environnementale et les perturbations structurent les communautés de fourmis de la litière en influençant la richesse, la diversité, l'abondance et la densité en espèces ainsi que les compositions taxonomique et fonctionnelle. Chaque type de formation végétale possède une communauté spécifique. La fragmentation et la conversion des forêts en plantations ont entrainé une altération plus ou moins profonde des communautés; cette variabilité est fonction du type d’agriculture et des espèces d'essences cultivées. Bien que l'altération des communautés se soit révélée maximale dans la plupart des monocultures, les plantations de cacaoyers ont un potentiel de conservation réel. Enfin, dans un contexte ou il est urgent de simplifier l'intégration des arthropodes dans les études de conservation, de contrôle et de suivi de la santé des écosystèmes terrestres, la méthode des réseaux de neurones est apparue comme un outil puissant pour mettre en évidence et analyser les patrons des communautés de fourmis.
Ants are reliable and relevant target organisms for environmental surveys. In our study, we focused on litter-dwelling ants through the use of two complementary sampling methods that were implemented according to the ants of leaf litter (all) protocol. In pristine forests of french guiana, leaf-litter ant communities are structured by environmental heterogeneity and natural perturbations - which influence species richness, diversity, abundance and density, as well as taxonomic and functional composition. This results in habitat-specific communities for each vegetal formation. Forest fragmentation and conversion into monocultures have led to a more or less deep alteration of the ant communities; this variability depends on the type of agricultural system and cultivated tree species. Although the intensity of community alteration peaked in tree monocultures, cocoa plantation exhibited a real potential for native species conservation. Finally, in the current context where simplifying the integration of arthropods into conservation programs as well as into surveys designed to monitor and manage the environment is critical, the use of neural networks appears to be a powerful tool for reliably highlighting and analyzing ant communities patterns.

http://www.theses.fr/2011AGUY0475/document

Éditeur(s) : AgroParisTech, ABIES
Résumé : Aquaculture is one of the main supply of protein in feed for mankind, notably in Asia. It increases and had exceeded the level of production of world fisheries, which is decreasing. According to sites and rearing methods, aquaculture contributes to add value but also in some cases to impact negatively the aquatic ecosystems. In the coastal area, a rich and productive zone, but also a place of conflicts, this activity presents a high potential for development if it takes into account the rules of sustainability. The conditions of this sustainability may be cleared with appropriate methods of foresight analysis applied for each development project. The analysis of the professional experience of D. Lacroix for 33 years in aquaculture is structured in three steps. Firstly, the work is to check the scientific value of the research conducted under his responsibility in various contexts and for different responsibilities. This study refers to the requirements of a PhD. In the second part of the work, the results of few major projects (French West Indies, French Guyana….) are analysed with the support of the theory of translation (Callon et al) which allows to build a network of actors and to project it into the context. This way of study includes a special attention to the aspects of time planning, legitimacy and acceptability. Finally, the author examines how this knowledge gained from experience could help building a method for foresight analysis aiming at a shorter planning, a better timing and less means for future projects. To achieve this goal the author integrates the vision of the economist R. Passet which structures any project in an ecosystemic framework, including criteria of sustainability. The mix of these two approaches (Callon & Passet) entails in a new tool for foresight analysis, called Aster, which originality is to offer the possibility to test various scenarios and related consequences to help decision -makers. This new method of foresight analysis, is then tested on the well known case study of the development of prawn Macrobrachium rosenbergii in French Guyana. The test shows to be successful as it delivers precise and arguable recommendations about research and development for all stakeholders.
L'aquaculture est l'une des composantes principales de l'apport en protéines dans le monde, surtout en Asie. Elle croît, alors que la pêche, qu'elle a dépassée en tonnage comme en valeur, décline. Selon les écosystèmes et les méthodes employées, elle peut contribuer à valoriser, mais aussi à dégrader les milieux aquatiques. Dans la zone côtière, espace riche et productif au plan biologique mais convoité, l'aquaculture conserve un potentiel de développement si sa mise en œuvre intègre les principes de la durabilité. Celle-ci peut être éclairée par la prospective avec des méthodes d'analyse adaptées à chaque projet. L'analyse de l'expérience de 33 ans en aquaculture de D. Lacroix est faite en trois temps. D'abord, il s'agit de vérifier la qualité de ses travaux de recherche scientifique menés dans des contextes et avec des responsabilités variés en suivant la grille d'analyse de référence d'un doctorat. Ensuite, l'analyse consiste à prendre un recul critique sur les bilans de réalisations majeures (Antilles, Guyane…) en mobilisant l'approche de M. Callon dont la théorie de la traduction permet de construire le réseau des acteurs et de le projeter dans la problématique. Cette grille d'analyse est complétée par l'étude des aspects de temporalité, légitimité et d'acceptabilité pour chaque réalisation. Ce travail sur diverses situations d'intervention permet de préparer une réflexion sur la proposition méthodologique qui suit et son adaptation à des conditions variables. Enfin, les connaissances acquises sont synthétisées afin de construire une méthode de prospective qui permettrait de gagner en temps, en efficacité et en moyens sur des projets à venir. Pour cela, l'analyse s'appuie sur la vision de R. Passet, qui structure les éléments de tout projet dans la hiérarchie des composantes de la durabilité. Le système dynamique qui en résulte peut être alors croisé avec divers scénarios afin d'en simuler les conséquences et donc d‟éclairer les choix. Cette méthode, dite Aster, est testée sur le cas « modèle » et bien documenté de l'élevage de la crevette Macrobrachium rosenbergii en Guyane française. Elle permet d'aboutir à des recommandations précises et argumentées en matière de recherche comme de développement pour tout décideur impliqué.

Droits : 2010 The author, AgroParisTech, ABIES
http://archimer.ifremer.fr/doc/00032/14349/11633.pdf
http://archimer.ifremer.fr/doc/00032/14349/

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : During the last couple of decades, the countries of the world have become increasingly interconnected into a single capitalist economic system. Globalization processes have facilitated the flow of goods and services. They have also led to new forms of exclusion, inequality and “culture conflict”. This paper elaborates on the nexus between transnational organized crime networks, fundamental Islamic movements and terrorist groups in the Balkan region, and argues that these movements for social, political and economic change are bi-products of globalization. After the fall of the Soviet Union, criminal-political formations expanded drastically in the newly emerging Balkan democracies. The weak government structures, the deteriorating domestic economy and the vulnerable government institutions made the Balkan region a safe haven for war profiteers, career criminals and fundamental Islamists. This paper gives a detailed overview of the origin, nature and expansion of several politicized illicit markets in the Balkans. It further elaborates on the birth of fundamental Islamic movements after communism. The complex interrelation between globalization, wars, organized crime and fundamental Islam is at the forefront of this paper.
Durant les deux dernières décennies, le monde s’est intégré dans un seul système économique capitaliste. Alors que les processus de mondialisation ont facilité les flux de biens et de services, ils ont aussi mené à des formes nouvelles d’exclusion, d’inégalité et de « conflit culturel ». Cet essai offre une réflexion sur le lien entre les réseaux transnationaux du crime organisé, les mouvements islamiques radicaux et les groupes terroristes dans la région des Balkans. Il soutient l’idée selon laquelle ces mouvements qui luttent pour le changement social, politique et économique sont les conséquences directes de la mondialisation. Après la chute de l’Union Soviétique, les formations politico-criminelles se sont rapidement accrues au sein des démocraties balkaniques émergentes. La fragilité des structures gouvernementales, la détérioration de l’économie domestique et la vulnérabilité des institutions ont transformé la région balkanique en lieu idéal pour ceux qui font des conflits armés leur fonds de commerce, pour les criminels de carrière ainsi que pour les intégristes islamiques. Cette recherche offre une analyse détaillée de l’origine, de la nature et du développement de plusieurs marchés illicites dans la région des Balkans. Elle se penche aussi sur l’origine des mouvements intégristes islamiques depuis la fin du communisme. Au cœur de cette analyse se loge donc l’interface entre la mondialisation, les conflits armés, le crime organisé et l’intégrisme islamique.
Kosovo

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5871
http://journals.openedition.org/etudescaribeennes/5871

Éditeur(s) : HAL CCSD Society for the Study of Reproduction
Résumé : International audience
Spermmotility notably depends on the structural integrity of the flagellum and the regulation ofmicrotubule dynamics. Although researchers have started to use " omics" techniques to characterize the human sperm's molecular landscape, the constituents responsible for the assembly, organization, and dynamics of the flagellum microtubule have yet to be fully defined. In this study, we defined a core set of 116 gene products associated with the human sperm microtubulome (including products potentially involved in abnormal ciliary phenotypes and male infertility disorders). To this end, we designed and applied an integrated genomics workflow and combined relevant proteomics, transcriptomics, and interactomics datasets to reconstruct a dynamic interactome map. By further integrating phenotypic information, we defined a disease-interaction network; this enabled us to highlight a number of novel factors potentially associated with altered sperm motility and male fertility. Lastly, we experimentally validated the expression pattern of two candidate genes (CUL3 and DCDC2C) that had never previously been associated with male germline differentiation. Our analysis suggested that CUL3 and DCDC2C's products have important roles in the sperm flagellum. Taken as a whole, our results demonstrate that an integrated genomics strategy can highlight relevant molecular factors in specific sperm components. This approach could be easily extended by including other " omics" data (from asthenozoospermic men, for example) and identifying other critical proteins from the human sperm microtubulome. Summary Sentence Although researchers have started to use "omics" techniques to characterize the human sperm's molecular landscape, the constituents responsible for the assembly, organization, and dynamics of the flagellum microtubule have yet to be fully defined.
ISSN: 0006-3363

hal-01515563
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01515563
DOI : 10.1095/biolreprod.116.143479
PUBMED : 28395323

Résumé : L’objet de cette thèse est de présenter les spécificités épidémiologiques, étiologiques et thérapeutiques de la pathologie neurovasculaire dans la population noire spécifique que constitue la population martiniquaise. En 1998, l’étude ERMANCIA I a permis de mettre en évidence une surincidence des accidents vasculaires cérébraux (AVC) en Martinique d’environ 40% par rapport à la métropole avec une haute prévalence de l’hypertension artérielle et du diabète. Ces résultats ont participé à la création en 2003 de la 1ère unité neurovasculaire aux Antilles. Le suivi à 5 ans des patients ERMANCIA I a révélé que la moitié était décédée et que 50% des survivants présentaient une démence vasculaire (soit le double des cohortes métropolitaines), probablement favorisé par une microangiopathie cérébrale sous-jacente souvent sévère amplifiant l’impact cognitif de l’AVC. Ce suivi a également permis d’identifier les faiblesses de la prévention secondaire en Martinique avec près de 80% des hypertendus qui restent mal équilibrés justifiant la création en 2006 d’un réseau de prévention. L’efficacité de ce réseau a été évaluée montrant un taux élevé de bon contrôle tensionnel (74% vs 39%, p=0,01) et une morbi-mortalité vasculaire moindre à 2,5 ans (8,3% vs 24%, p<0,001) que chez les patients contrôles. En 2012, ERMANCIA II a permis de révéler une diminution majeure (en moyenne 30%) de l’incidence des AVC dans la population martiniquaise et de la mortalité à 1 mois pour les patients ≤55 ans (20% vs 8%, p=0,03) probablement en raison d’une meilleure implémentation des mesures de prévention primaire et de la prise en charge en UNV respectivement. Nos données ont également permis de décrire certaines spécificités étiologiques des AVC chez les Martiniquais : grande fréquence de l’athérome intracrânien (pour lequel nous apportons des arguments en faveur d’une nouvelle classification), infarctus choroïdiens antérieurs dont nous décrivons le profil évolutif particulier, infarctus lacunaires multiples sévères. Deux étiologies plus « classiques » comme la drépanocytose et les IC sur morsure de serpent sont devenues anecdotiques. En revanche, une dysplasie carotidienne focale, étiologie déjà décrite mais supposée rare , pourrait être responsable d’un tiers des infarctus carotidiens d’origine indéterminée chez les Afro-Caribéens ≤55 ans exposant à un risque élevé de récidive sous traitement antiagrégant (28% à 14 mois), contre aucun pour les patients traités par endartériectomie. Sur le plan thérapeutique, nos résultats sont en faveur d’un surrisque hémorragique de la thrombolyse standard chez les patients martiniquais les plus âgés, probablement en rapport avec un cumul de lésions microangiopathiques plus important. En l’absence de neuroradiologie interventionnelle en Martinique, nos travaux montrent que certains patients avec occlusion artérielle proximale résistante à la thrombolyse IV standard peuvent bénéficier d’un complément de thrombolytique (0,1mg/Kg de tenecteplase). Une étude randomisée est prévue afin de mieux mesurer le potentiel thérapeutique de cette stratégie. Pour conclure, l’intérêt de ces données est que la population martiniquaise partage très probablement beaucoup de ses « particularités » avec d’autres populations noires encore peu décrites et pour lesquelles l’occidentalisation progressive du mode de vie risque d’accentuer le fardeau représenté par les AVC.
Our work presented herein aimed to describe the epidemiological, etiological and therapeutic features of the stroke pathology in the Martinican Afro-Caribbean population. In 1998, the first population-based epidemiological study, ERMANCIA I, showed a 40% greater firstever stroke incidence in Martinique compared to those observed in continental France, with a high prevalence of hypertension and diabetes. These results contributed to the creation, in 2003, of the first stroke unit in the Caribbean area. In the 5_year follow-up study, we found that half of the patients had died and that 50% of survivors were affected from vascular dementia (twice compared with continental French cohorts): this figure was probably favored by severe underlying cerebral microangiopathy that amplified the cognitive impact of stroke. We also identified a failure in the secondary prevention in Martinique, certified by nearly 80% of hypertensive patients still insufficiently controlled. As a result, in 2006, we developed a well-structured stroke prevention network. The efficiency of this network was attested by the high rate of good blood pressure control (74% vs. 39%, p=0.01) and the reduced vascular morbidity and mortality rate (8.3% vs. 24%, p <0.001) after a 30-month period of activity, in comparison with control “historic” patients. In 2012, ERMANCIA II study revealed a 30% reduction of first-ever stroke incidence and a reduced mortality rate at 1 month for patients ≤55 years (8% vs. 20%, p = 0.03), compared to these observed in ERMANCIA I, likely due to improvement of primary stroke prevention and the best stroke unit management at the acute phase, respectively. Based on our etiological data, we underline: 1) the relatively high frequency of symptomatic intracranial atherosclerosis, for which we propose a new definition; 2) the clinic-radiological features of stroke in the anterior choroidal artery; 3) the atypical picture of “malignant” multilacunar syndrome. On the other hand, stroke due to sickle cell disease or “trigonocephale” snakebite were only anecdotal. However, we found that carotid-bulb atypical fibromuscular dysplasia (CAFD), a very unusual previously described cause of stroke, could be responsible for up to the third of carotidterritory stroke of so-called undetermined etiology among patients ≤55 years. In addition, the relatively high rate of recurrence under antiplatelet (28% at 14 months), was dramatically reduced by endarterectomy in patients with CAFD. From a therapeutic point of view, our results showed an excess rate of post-thrombolysis symptomatic intracerebral hemorrhages in older patients, a figure probably linked to the severe underlying hypertension-triggered cerebral microangiopathy. Owing to the lack of neurointerventionnal option in Martinique, we tested a new therapeutic strategy in patients with a proximal arterial occlusion not responsive to standard IV thrombolysis, consisting in an additional administration of IV tenecteplase, 0.1mg/kg. Our preliminary results were promising, leading us to plan a randomized study. Finally, most of the characteristics of stroke in this Afro-Caribbean population are probably shared by the majority of black people. Thus, our results could have a universal impact in the understanding of stroke burden in blacks.

http://www.theses.fr/2015AGUY0909/document