Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
ISSN: 0003-4975

hal-01563338
http://hal.univ-brest.fr/hal-01563338
DOI : 10.1016/j.athoracsur.2016.03.093
PUBMED : 27262916

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Aims: The aims of this study were to compare short-and long-term outcomes for clinical T2N0 oesophageal cancer with analysis of (i) primary surgery (S) versus neoadjuvant therapy plus surgery (NS), (ii) squamous cell carcinoma and adenocarcinoma subsets; and (iii) neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy.Methods: Data were collected from 30 European centres from 2000 to 2010. Among 2944 included patients, 355 patients (12.1%) had cT2N0 disease; 285 (S) and 70 (NS), were compared in terms of short-and long-term outcomes. Propensity score matching analyses were used to compensate for differences in baseline characteristics.Results: No significant differences between the groups were shown in terms of in hospital morbidity and mortality. Nodal disease was observed in 50% of S-group at the time of surgery, with 20% pN2/N3. Utilisation of neoadjuvant therapy was associated with significant tumour downstaging as reflected by increases in pT0, pN0 and pTNM stage 0 disease, this effect was further enhanced with neoadjuvant chemoradiotherapy. After adjustment on propensity score and confounding factors, for all patients and subset analysis of squamous cell and adenocarcinoma, neoadjuvant therapy had no significant effect upon survival or recurrence (overall, loco-regional, distant or mixed) compared to surgery alone. There were no significant differences between neoadjuvant chemotherapy and chemoradiotherapy in short-or long-term outcomes.Conclusion: The results of this study suggest that a surgery alone treatment approach should be recommended as the primary treatment approach for cT2N0 oesophageal cancer despite 50% of patients having nodal disease at the time of surgery.
ISSN: 0959-8049

hal-01666517
https://hal.univ-lorraine.fr/hal-01666517
DOI : 10.1016/j.ejca.2015.11.024

Éditeur(s) : HAL CCSD
Résumé : In this paper we define the $p$-density of a finite subset $Dsubsetma{N}^r$, and show that it gives a good lower bound for the $p$-adic valuation of exponential sums over finite fields of characteristic $p$. We also give an application: when $r=1$, the $p$-density is the first slope of the generic Newton polygon of the family of Artin-Schreier curves associated to polynomials with their exponents in $D$.
https://hal.archives-ouvertes.fr/hal-00551478

hal-00551478
https://hal.archives-ouvertes.fr/hal-00551478
ARXIV : 0812.3382

Éditeur(s) : HAL CCSD Impact journals
Résumé : International audience
Targeted therapies have substantially changed the management of non-small cell lung cancer (NSCLC) patients with driver oncogenes. Given the high frequency, EGFR and ALK aberrations were the first to be detected and paved the way for tyrosine kinase inhibitor (TKI) treatments. Other kinases such as ROS1 and more recently RET have emerged as promising targets, and ROS1 and RET TKIs are already available for precision medicine. We screened a large cohort of 713 Caucasian non-squamous NSCLC patients lacking EGFR/KRAS/BRAF/HER2/PI3KCA/ALK aberrations for ROS1 and RET rearrangements using fluorescence in situ hybridization to determine the frequency and clinicopathological characteristics of ROS1- and RET-positive patients. Frequencies of ROS1 and RET rearrangements were 2.1% and 2.52%, respectively. Contrary to common belief, both ROS1 and RET rearrangements were detected in patients with a history of smoking, and the RET-positive patients were not younger than the negative patients. Moreover, RET but not ROS1 rearrangement was associated with the female gender. Nearly half of the ROS1-rearranged patients were successfully treated with ROS1 TKIs. In contrast, only 5/18 RET-positive patients received off-label RET TKIs. Two patients had stable disease, and three experienced disease progression. In addition to the 18 RET-positive cases, 10 showed isolated 5' signals. The clinical relevance is unknown but if the frequency is confirmed by other groups, the question whether these patients are eligible to TKIs will arise. More potent RET TKIs are under development and may improve the response rate in RET-positive patients. Therefore, we recommend the routine implementation of RET testing in non-squamous NSCLC patients, including those with a history of smoking.
ISSN: 1949-2553

hal-01578586
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01578586
DOI : 10.18632/oncotarget.18408
PUBMED : 28881815

Éditeur(s) : HAL CCSD
Résumé : National audience
RFIA
Lyon, France

hal-01313397
https://hal.archives-ouvertes.fr/hal-01313397

Éditeur(s) : HAL CCSD
Résumé : National audience
Actes du 20ième colloque du GRETSI (2005)
Louvain-la-Neuve, Belgium

hal-00605242
https://hal.archives-ouvertes.fr/hal-00605242

Éditeur(s) : HAL CCSD
Résumé : International audience
Proceedings of IEEE Power Engineering Society General Meeting, 2007.

hal-00692555
https://hal.archives-ouvertes.fr/hal-00692555

Éditeur(s) : HAL CCSD
Résumé : International audience
Proceedings - 26th IEEE International Conference on Advanced Information Networking and Applications Workshops, WAINA 2012
Fukuoka, Japan

hal-00755765
https://hal.archives-ouvertes.fr/hal-00755765

Éditeur(s) : HAL CCSD
Résumé : Session "Articles"
National audience
Nous présentons ici une méthode permettant de créer et de représenter sous forme vectorielle des classes de transition à partir d'une classification supervisée basée sur des arbres de décision flous. Cette méthode est particulièrement utile pour la classification stricte de données dont les frontières sont naturellement diffuses ainsi que pour leur représentation au sein d'un System d'Information Géographique. C'est le cas par exemple des formations forestières entre lesquels les transitions sont généralement étalées sur plusieurs centaines de mètres avec des gradients dépendant de condition environnementales locales ne permettant pas de définir une transition identique dans toutes les directions. La méthode présentée permet d'ajouter des classes lorsque les zones de transition sont trop étendues plutôt que de fixer une frontière arbitrairement
Actes de la conférence RFIA 2012
Lyon, France

Droits : info:eu-repo/semantics/OpenAccess
hal-00656502
https://hal.archives-ouvertes.fr/hal-00656502
https://hal.archives-ouvertes.fr/hal-00656502/document
https://hal.archives-ouvertes.fr/hal-00656502/file/rfia2012_submission_57.pdf

Éditeur(s) : HAL CCSD
Résumé : National audience
7ème Atelier Fouille de Données Complexes dans un processus d'extraction de connaissances - Complexité liée aux données multiples
Hammamet, Tunisia

hal-00604032
https://hal.archives-ouvertes.fr/hal-00604032

Éditeur(s) : HAL CCSD
Résumé : International audience
Proceedings of 2004 IEEE International Conference on Fuzzy Systems

hal-00605239
https://hal.archives-ouvertes.fr/hal-00605239

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
ISSN: 0950-7051

hal-00604031
https://hal.archives-ouvertes.fr/hal-00604031

Éditeur(s) : HAL CCSD
Résumé : In this paper we compute the first vertex of a generic Newton polygon in some special cases, and the corresponding Hasse polynomial. This allows us to show the nonexistence of $p$-cyclic coverings of the projective line in characteristic $p$ with supersingular jacobian for some (infinite families of) genera.
https://hal.archives-ouvertes.fr/hal-00551456

hal-00551456
https://hal.archives-ouvertes.fr/hal-00551456
ARXIV : 0912.2051

Éditeur(s) : HAL CCSD InTech
Applied Biological Engineering - Principles and Practice

ISBN : 978-953-51-0412-4
hal-00683825
https://hal.archives-ouvertes.fr/hal-00683825

Éditeur(s) : HAL CCSD
Résumé : International audience
“Affective Computing is computing that relates to, arises from, or deliberately influences emotions” (R.W. Picard, MIT Press, 1997). Specifically, psychosocial equilibrium is now considered as a major issue for both individual and public health. Predicting human emotions via non-intrusive methods is a great challenge triggered by the rise of intelligent assisting systems. In order to determine the emotional state of a subject having a potential psychosocial disorder, it is required to process both neutral and expressive emotions. A computer-engineered method aiming to provide emotional information from videos is proposed. An original approach for affect classification and its interpretation is presented.The database is part of the HUMAINE database, and consists of a large volume of video clips, each displaying individuals, depressed or not, talking with a conversational agent. Both the high-dimensionality of data and its temporal aspect require a pre-training that consists of cleaning, sorting and feature selection, in order to make relevant information usable for further processing by MachineLearning methods. Next step consists in classifying the affective state of subjects according to their positivity or negativity (Russell's model, 1980). By means of six independent classifiers, each running a Support Vector Machine algorithm, separate performances are obtained for each class of emotions. The results reveal an interesting “neutral area phenomenon”, where emotions tend to be harder to be detected.Though more frequent, neutral emotions seem to carry less discriminant information than expressive ones. This issue will be a key for designing a tuning step in further research.
Caribbean Academy Of Science
Deshaies, France

hal-01408029
https://hal.univ-antilles.fr/hal-01408029

Éditeur(s) : HAL CCSD
Résumé : International audience
In this paper, we use a segmentation method applied to the plants images analysis. The segmentation gives groups of pixels, and we propose to use merging operators to address the most relevant groups in order to improve the recognitions systems performance. In particular, we use an operator called Pi fully reinforced. The experiments carried out show that the use of Pi improves outcomes for structuring groups of pixels.
Advanced Information Networking and Applications
Fukuoka, Japan

hal-00652125
https://hal.archives-ouvertes.fr/hal-00652125
DOI : 10.1109/WAINA.2012.40

Éditeur(s) : HAL CCSD
Résumé : International audience
Progress in Pattern Recognition, Image Analysis, Computer Vision, and Applications Lecture Notes in Computer Science

hal-00855088
https://hal.archives-ouvertes.fr/hal-00855088

Éditeur(s) : HAL CCSD
Résumé : Document soutenu à l'atelier Fouille de Données Complexes de la conférence EGC2017
International audience
"L'informatique affective est l'informatique qui se réfère à, résulte de, ou influence délibérément les émotions" (Picard (1997)). Singulièrement, l'équi-libre psychosocial est désormais considéré comme une préoccupation majeure pour la santé, tant sur le plan individuel que public. Prédire les émotions hu-maines via des méthodes non-invasives est un challenge propulsé notamment par le développement des systèmes d'accompagnement intelligents. Afin de dé-terminer l'état émotionel d'un individu, ayant potentiellement un trouble psy-chosocial, il convient de traiter tant les émotions expressives que neutres. Une approche originale de classification de l'information émotionelle à partir de vi-déos est proposée.
Extraction et Gestion des Connaissances
Grenoble, France

Droits : http://creativecommons.org/licenses/by-nc-sa/
hal-01513329
https://hal.archives-ouvertes.fr/hal-01513329
https://hal.archives-ouvertes.fr/hal-01513329/document
https://hal.archives-ouvertes.fr/hal-01513329/file/egcArticle%20scholet.pdf

Éditeur(s) : HAL CCSD
Résumé : International audience
Proceedings of Fifth International Conference on Research Challenges in Information Science (RCIS), 2011
Gosier (Guadeloupe), France

hal-00688162
https://hal.archives-ouvertes.fr/hal-00688162
DOI : 10.1109/RCIS.2011.6006871

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
We show that, for any finite field Fq , there exist infinitely many real quadratic function fields over Fq such that the numerator of their zeta function is a separable polynomial. As pointed out by Anglès, this is a necessary condition for the existence, for any finite field Fq, of infinitely many real function fields over Fq with ideal class number one (the so-called Gauss conjecture for function fields). We also show conditionally the existence of infinitely many real quadratic function fields over Fq such that the numerator of their zeta function is an irreducible polynomial.
ISSN: 0022-314X

hal-00978911
https://hal.archives-ouvertes.fr/hal-00978911
https://hal.archives-ouvertes.fr/hal-00978911/document
https://hal.archives-ouvertes.fr/hal-00978911/file/AubryBlache5_10.pdf
DOI : 10.1016/j.jnt.2007.10.014