Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
In East Asia, widespread extensional sedimentary basins together with the close association of Metamorphic Core Complexes and magmatism are prominent features of the large-scale wide rift system developed during late Mesozoic times. This region thus appears as a proper place to study continental extension as well as questions about the link between continental extension and magmatism. This paper primarily provides pioneer exhumation time-constraints on the Linglong MCC (Jiaodong Peninsula) including cooling and deformation ages. MCC cooling at mid-crustal levels occurred at ca. 143 Ma. Besides, last ductile deformation occurred at ca. 134 Ma while final exhumation stages, under brittle 2 conditions, occurred as late as ca. 128 Ma. Continuous crustal stretching were then recorded by the emplacement of a synkinematic pluton in the upper crust at ca. 128 Ma that cooled fast below an intracrustal shear zone crossing the ductile-brittle transition at ca. 123 Ma. The ca. 120-118 Ma age cluster is ascribed to the fast cooling of undeformed plutons marking the end of extension that lasted, in the area, over a minimum period of ca. 30 My. Combining other MCC exhumation constraints and the onset of subsidence in the sedimentary basins, total duration of late Mesozoic extension in East Asia could be estimated at ca. 60 My, related with a rather long process for extension from 160 to at least 100 Ma. East Asian continental extension is heterogeneously distributed in space and time as revealed by fundamental differences between two end-member classes of migmatite-cored MCC already described in other wide rift systems. Extension seems to have first favoured partial melting which subsequently, in turn, maintained continental extension.
ISSN: 1342-937X

insu-00752551
https://hal-insu.archives-ouvertes.fr/insu-00752551
https://hal-insu.archives-ouvertes.fr/insu-00752551/document
https://hal-insu.archives-ouvertes.fr/insu-00752551/file/Charles_et_al_Gondwana_Research_2012.pdf
DOI : 10.1016/j.gr.2012.10.011

Éditeur(s) : HAL CCSD
Résumé : International audience
Dans ce travail, nous analysons les données concernant les articles publiés à la conférence EGC. Notre objectif est d’identifier et de comprendre les tendances en matière de collaborations. Pour ce faire, nous adoptons une modélisation descriptive, à travers une approche réseau qui consiste à générer tout d’abord le réseau de collaborations des auteurs à partir des données. Nous enrichissons ensuite les noeuds de ce réseau d’une dizaine d’attributs individuels extraits à partir des données. Enfin, nous recherchons des vues conceptuelles, une approche récente de clustering de liens, qui permet de synthétiser des réseaux en mettant en évidence les ensembles d’attributs retrouvés fréquemment liés dans le réseau. Les résultats obtenus montrent les tendances existantes dans les comportements de collaborations. Dans ce papier, nous présentons ces tendances et montrons comment elles évoluent selon différents seuils d’extraction.
Extraction et gestion des connaissances
Reims, France

hal-01312559
https://hal.archives-ouvertes.fr/hal-01312559

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The Blake excursion was among the first recognized with directional and intensity behavior known mainly from marine sediment and Chinese loess. Age estimates for the directional shifts in sediments are poorly constrained to about 118−100 ka, i.e., at the marine isotope stage (MIS) 5e/5d boundary. Moreover, sediments at Lac du Bouchet maar, France and along the Portuguese margin reveal what may be a "post-Blake" excursion at about 105−95 ka. The excursional directions are associated with a prominent paleointensity minimum between about 125 and 95 ka in global stacked records. Lava flow recordings of the Blake excursion(s) have, however, been questionable because precise ages required for correlation with these sediment records are lacking. To establish new, independent records of the Blake excursion, and link these into a larger Quaternary GITS, we have undertaken 40Ar/39Ar incremental heating and unspiked K-Ar experiments on groundmass from the transitionally magnetized Inzolfato flow on Lipari Island. We also obtained 40Ar/39Ar incremental heating results for a lava flow on Amsterdam Island originally thought to record the Mono Lake excursion and from the transitionally magnetized El Calderon basalt flow, New Mexico that was K-Ar dated by Champion et al. (1988) at 128 ± 66 ka. Unspiked K-Ar ages of four samples from the Inzolfato flow are 102.5 ± 4.7, 101.3 ± 3.3, 97.1 ± 2.6, and 96.8 ± 3.1 ka and thus indistinguishable from one another. 40Ar/39Ar results are more complex, with three samples yielding discordant age spectra. Based on incremental heating data obtained in both the UW-Madison and Gif-sur-Yvette 40Ar/39Ar laboratories, a fourth sample yields six concordant age plateaus and a weighted mean age of 105.2 ± 1.4 ka that we take as the best estimate of time since the flow erupted. Five 40Ar/39Ar incremental heating experiments on the Amsterdam Island lava yield a plateau age of 120 ± 12 ka, whereas ages from two sites in the Calderon flow are 112 ± 23 and 101 ± 14 ka, together giving a weighted mean of 104 ± 12 ka. The age of 120 ± 12 ka from Amsterdam Island, though imprecise, correlates with the Blake excursion. In contrast, the 104-105 ka age obtained from both Lipari and New Mexico indicates that these lavas record a younger period of dynamo instability, most probably associated with the post-Blake excursion. These radioisotopic ages are consistent with the astronomical ages of two paleointensity minima in the PISO-1500 global stack. Our findings indicate that the Blake and post-Blake excursions are both global features of past geodynamo behavior and support the hypothesis that Brunhes chron excursions are temporally clustered into two groups of at least a half-dozen each spanning over 220 to 30 ka and 720 to 520 ka.
ISSN: 1871-1014

hal-01054336
https://hal.archives-ouvertes.fr/hal-01054336
DOI : 10.1016/j.quageo.2012.12.005

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Glioblastoma (GB), the most frequent primary tumor of the central nervous system, remains one of the most lethal human cancers despite intensive researches. Current paradigm in the study of GB has been focused on inter-patient variability and on trying to isolate new classification elements or prognostic factors. Here, using ICPL, a technique for protein relative quantification by mass spectrometry, we investigated protein expression between the four regions of GB on clinically relevant biopsies from 5 patients. We identified 584 non-redundant proteins and 31 proteins were found to be up-regulated in the tumor region compared to the peri-tumoral brain tissue, among which, 24 proteins belong to an interaction network linked to 4 biological processes. The core of this network is mainly constituted of interactions between beta-actin (ACTB) with heat shock proteins (HSP90AA1, HSPA8) and 14-3-3 proteins (YWHAZ, YWHAG, YWHAB). A cluster of three isoforms of the sodium pump α-subunit (ATP1A1, ATP1A2, ATP1A3) was also identified outside this network. The differential expression observed for ACTB and 14-3-3γ was further validated by western blot and/or immunohistochemistry. Our study confirms the identity of previously proposed molecular targets, highlights several functional processes altered in GB such as energy metabolism and synaptic transmission and could thus provide added value to new therapeutic trails.
ISSN: 1874-3919

hal-00877756
https://hal.archives-ouvertes.fr/hal-00877756
DOI : 10.1016/j.jprot.2012.04.034
PUBMED : 22575386

Éditeur(s) : HAL CCSD Wiley-Blackwell
Résumé : International audience
Understanding the distribution of genetic diversity in the light of past demographic events linked with climatic shifts will help to forecast evolutionary trajectories of ecosystems within the current context of climate change. In this study, mitochondrial sequences and microsatellite loci were analysed using traditional population genetic approaches together with Bayesian dating and the more recent approximate Bayesian computation scenario testing. The genetic structure and demographic history of a commercial fish, the black scorpionfish, Scorpaena porcus, was investigated throughout the Mediterranean and Black Seas. The results suggest that the species recently underwent population expansions, in both seas, likely concomitant with the warming period following the Last Glacial Maximum, 20 000 years ago. A weak contemporaneous genetic differentiation was identified between the Black Sea and the Mediterranean Sea. However, the genetic diversity was similar for populations of the two seas, suggesting a high number of colonizers entered the Black Sea during the interglacial period and/or the presence of a refugial population in the Black Sea during the glacial period. Finally, within seas, an east/west genetic differentiation in the Adriatic seems to prevail, whereas the Black Sea does not show any structured spatial genetic pattern of its population. Overall, these results suggest that the Black Sea is not that isolated from the Mediterranean, and both seas revealed similar evolutionary patterns related to climate change and changes in sea level.
ISSN: 1471-8278

hal-01330323
https://hal-univ-perp.archives-ouvertes.fr/hal-01330323
DOI : 10.1111/mec.13616

Éditeur(s) : American Geophysical Union
Résumé : Magmatism associated with subducting plate edges or slab tears has been suggested in the southern Okinawa Trough. The cross back-arc volcanic trail, which consists of a cluster of about 70 seamounts, is located above a Ryukyu slab tear lying along the 123.3°E meridian. In November 2003, more than 3300 earthquakes recorded in this area by 15 ocean bottom seismometers and surrounding land stations during a period of 12 days were used to determine the three-dimensional Vp and Vs velocity structures and Vp/Vs ratios. A mantle inflow characterized by low Vp and Vs and high Vp/Vs passing through the slab tear is imaged. The fluid and/or melt component is rising obliquely from the slab tear in the directions of the cross back-arc volcanic trail, the northern slope of the southern Okinawa Trough and to north of Iriomote Island. The asthenospheric intake is also imaged by an inclined chip-like high Vp/Vs and low Vp and Vs body dipping northerly, which might be linked to the slab retreat. West of the slab tear, most of the earthquakes are located around low Vp and Vs and high Vp/Vs bodies, which suggests that the seismicity is related to magmatic and/or fluid activities. East of it, earthquakes are concentrated in an area characterized by high Vp and Vs velocities and low Vp/Vs, suggesting that the magma chamber is absent beneath the axial part of the trough and that normal faulting is the main factor controlling the seismicity.
Journal of Geophysical Research ( JGR ) - Solid earth (0148-0227) (American Geophysical Union), 2007-08 , Vol. 112 , N. B8 , P. NIL_13-NIL_32

Droits : 2007 AGU
http://archimer.ifremer.fr/doc/2007/publication-3032.pdf
DOI:10.1029/2006JB004703
http://archimer.ifremer.fr/doc/00000/3032/

Éditeur(s) : HAL CCSD American Society for Microbiology
Résumé : International audience
: Estradiol signaling is ideally suited for analyzing molecular and functional linkages between the different layers of information directing transcriptional regulations: DNA sequence, chromatin modifications and the spatial organization of the genome. Hence, estrogen receptor (ER) can bind at a distance from its target genes and engages timely and spatially coordinated processes to regulate their expression. In the context of the coordinated regulations of co-linear genes, identifying which ER binding sites (ERBSs) regulate a given gene still remains a challenging question. Here, we investigated the coordination of such regulatory events at a 2 Mb genomic locus containing the estrogen-sensitive TFF cluster of genes in breast cancer cells. We demonstrated that this locus exhibits a hormone and cohesin-dependent reduction in the plasticity of its three-dimensional organization that allows multiple ERBSs to be dynamically brought to the vicinity of estrogen-sensitive genes. Additionally, by using triplex forming oligonucleotides, we could precisely document the functional links between ER engagement at given ERBSs and the regulation of particular genes. Hence, our data evidence a formerly suggested cooperation of enhancers towards gene regulations, and also show that redundancy between ERBSs can occur.
ISSN: 0270-7306

hal-00984591
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00984591
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00984591/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00984591/file/Mol._Cell._Biol.-2014-Quintin-MCB.00918-13.pdf
DOI : 10.1128/MCB.00918-13

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Forecasting of sea-state characteristics, with warning time of a few hours, appears a necessity in Operational Oceanography. linking sophisticated marine monitoring systems with forecasting modeling tools. In this paper, instead of using conventional numerical models, a Takagi-Sugeno-rule-based Fuzzy Inference System (FIS) was developed aiming at forecasting wave parameters based on the wind speed and direction, and the lagged-wave characteristics. Initial and final antecedent fuzzy membership functions were identified using the subtractive clustering method. The model was applied on the wind and wave dataset recorded in years 2000-2006 by an oceanographic buoy deployed in the Aegean Sea. The model showed perfect fit for the training period (2000-2005; 12,274 data points), and expanded its hindcasting ability during 2006 (1044 data points), as the verification part of the series. Model results, for a lead time of 3 h, showed good agreement between the predicted and the observed significant wave height (RMSE=0.216) and zero-up-crossing period (RMSE=0.315). According to other model performance criteria, the fuzzy model slightly underpredicted both wave characteristics (the linear regression slope was 0.911 for wave height and 0.788 for wave period), and reduced its forecasting ability at higher prediction intervals (+6 to + 12 h). Overall, model results illustrated that the developed FIS could serve as a valuable tool for the operational prediction of wave characteristics in Northern Aegean Sea, through the utilization of the POSEIDON network.
ISSN: 0029-8018

hal-00456020
https://hal.archives-ouvertes.fr/hal-00456020
DOI : 10.1016/j.oceaneng.2009.08.016

Éditeur(s) : HAL CCSD
Résumé : One of the major challenges in forest ecology is to understand the ecology, physiology and potential responses of the> 250000 species of vascular plants of the planet through the categorization of this diversity into functional groups. This approach is essentially based on functional traits analysis, but few investigations were made in tropical areas. The aim of this study was to determine functional groups in two contrasted tropical ecosystems, dry (DF) and mountain rain (MRF) forest (respectively rainfall of 1 200 mm/year and 10 000 mm/year). Guadeloupe Island in FWI presents both these ecosystems spread over less 100 km. In a first time, we developed an original species typology based on 7 "soft" traits, easy to measure (stomatal density, leaf trichom density, chlorophyll content, leaf nitrogen content, specific leaf area, wood density, leaf area, plant height). The method was based on principal component analysis (PCA) and agglomerative hierarchical clustering (AHC) applied to these traits measured at the individual level (Blazy et al., 2009). In a second time, we evaluated the relevance of these soft trait-based groups compared to a typology based on 5 "hard" ecophysiological traits, more costly to quantify but with higher functional significance (difference between predawn and minimum leaf water potential, stomatal conductance, maximal carbon assimilation rate, leaf water potential at 90% of loss of stem hydraulic conductivity). When performed on the dominant canopy species in DF and MRF (a total of 13 species and 60 mature individuals), the typological approach based on soft traits seems relevant to discriminate groups with a distinct functional reality. Through both ecosystems, we obtained 4 homogenous groups. Two were exclusively composed by DF's or MRF's species, indicating that a functional strategy can be linked to specific environmental conditions. The two other groups showed a mix of DF and MRF species indicating that different functional strategies can coexist in the same environment. These mixed groups seem distinct by their ecophysiological features, particularly in term of hydraulic characteristics. One group was composed by drought tolerant species, water spender species, with a high xylem embolism resistance, whereas the second one was composed by water saver species, less resistant to embolism. Therefore, a determination of functional groups based on soft traits could be useful to model ecosystem's responses to environmental changes on a global scale.
Book of Abstracts - isem 2013 - Ecological Modelling for Ecosystem Sustainability
Toulouse, France

hal-00964668
https://hal.archives-ouvertes.fr/hal-00964668