Éditeur(s) : HAL CCSD National Institute of Environmental Health Sciences
Résumé : International audience
Background: Glycol ethers (GE) are widely used organic solvents. Despite the potential neurotoxicity of several families of organic solvents, little is known about the impact of GE on the neurodevelopment of infants and children. Objectives: We investigated the relation between urinary concentrations of GE metabolites in pregnant women and neurocognitive abilities in their 6-year-old children in the PELAGIE mother-child cohort. Methods: Five GE metabolites were measured in first morning void urine samples of 204 French pregnant women in early pregnancy (<19 weeks of gestation). Psychologists assessed the neurocognitive abilities of their 6-year-old children with the Wechsler Intelligence Scale for Children IV (WISC) and the Developmental Neuropsychological Assessment (NEPSY). We analyzed the results with linear (WISC) and Poisson regression models (NEPSY), adjusted for potential confounders, including child's stimulation at home. Results: GE metabolites were detected in 90-100% of maternal urine samples. The WISC Verbal Comprehension score was significantly lower for children with the highest tertile of urinary phenoxyacetic acid (PhAA) [beta (third vs. first tertile)=-6.53; 95% CI: -11.44, -1.62]. Similarly, the NEPSY Design Copying subtest score was lower in those with the highest tertile of urinary ethoxyacetic acid (EAA) [beta (third vs. first tertile)=-0.11; 95% CI: -0.21, 0.00]. The other GE metabolites we studied were not significantly associated with WISC or NEPSY scores. Conclusions: Prenatal urine concentrations of two GE metabolites were associated with lower WISC Verbal Comprehension Index scores and NEPSY Design Copying subscale scores, respectively, at age 6 years. PhAA is the primary metabolite of 2-phenoxyethanol (EGPhE), which is commonly found in cosmetics, and precursors of EAA are frequently used in cleaning agents. Additional research is needed to confirm our findings and further explore potential effects of prenatal GE exposures on neurocognitive performance in children.
ISSN: 0091-6765

hal-01519256
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01519256
DOI : 10.1289/EHP39
PUBMED : 27740510

Éditeur(s) : HAL CCSD Université des Antilles
Résumé : International audience
In this study, we propose to analyze the limits of mass tourism in the French Antilles, specifically the decline of tourism, economic limits, and ecological degradation). The recognition of these limits is overdue, and signals a need to define another model for tourism development.The popular coastal sector in the south of Martinique has been subject new regulations to protect marine resources. These regulations require the development of new practices and a greater level of awareness for tourists, for example, around coral reefs and mangroves. Ecotourism programs aim to demonstrate to visitors the forests rich natural resources and biodiversity in general. It also features the inclusion of small rural businesses that benefit from additional sources of revenue as a result of ecotourism.The situation in the French Antilles is complex: Urbanization is fraught with serious consequences for the coastline. Tourism products currently being marketed on the island are not competitive (particularly against the political dynamics of the neighbouring island of Dominica). Ecotourism and sustainable tourism are just beginning to develop in such destinations, where tourism has been declining in the last ten years. The situation of the French Antilles is paradoxical in a region that generally has a very favourable tourism. Assessing these limits through the scope of ecotourism helps to highlight the causes of these difficulties and to adapting to new tourism practices.
En el contexto de este estudio, nos proponemos analizar los límites del turismo de masas en las Antillas Francesas (depreciación del turismo, las limitaciones económicas, ecológicas y las molestias). Este reconocimiento de esos límites está en el origen de la conciencia tardía de la necesidad de definir otro modelo de desarrollo turístico.En el sector costero de la más popular, como en el sur de Martinica, se pone en la normativa nuevo lugar para proteger los recursos marinos. Esto requiere el desarrollo de nuevas prácticas y la sensibilización de los turistas, por ejemplo, alrededor de los arrecifes de coral y los manglares.Programas en torno al ecoturismo también tienen como objetivo dar al visitante la riqueza de los recursos forestales y la biodiversidad en general. También incluye las pequeñas empresas rurales que reciben los nuevos ingresos a través del turismo.Pero la situación es compleja en las Antillas francesas: la urbanización está llena de importantes consecuencias para la costa. Productos turísticos que se comercializan actualmente no son competitivos (en particular, contra la dinámica política de la cercana isla de Dominica). Ecoturismo y desarrollo sostenible están empezando a desarrollar en este destino turístico, donde el turismo está en problemas en los últimos diez años.Esta situación es bastante paradójico en un turismo regional muy favorable. Sin lugar a dudas, pensando en el ecoturismo contribuye a identificar los destinos de estos retrasos y dificultades para adaptarse a nuevas prácticas de turismo.
Dans le cadre de cette étude, l’accent est mis sur les limites du tourisme de masse dans les Antilles françaises (dépréciation du tourisme, les contraintes économiques et les nuisances écologiques). La reconnaissance de ces limites est à l'origine de la prise de conscience tardive de la nécessité de définir un autre modèle de développement touristique.Dans le sud de la Martinique, le secteur le plus populaire du littoral, de nouvelles règlementations sont mises en place pour protéger les ressources marines. Cela nécessite le développement de nouvelles pratiques et de sensibilisation des touristes notamment autour des récifs coralliens et les mangroves. Les programmes autour de l'écotourisme visent également à montrer aux visiteurs la richesse des ressources forestières et de la biodiversité en général. Il comprend également les petites entreprises rurales qui reçoivent de nouveaux revenus grâce au tourisme.La situation est complexe dans les Antilles françaises: l'urbanisation est lourde de conséquences importantes sur la côte. Les produits touristiques commercialisés actuellement ne sont pas compétitifs (notamment contre la dynamique politique de l'île voisine de la Dominique). L'écotourisme et le tourisme durable commencent tout juste à se développer dans ces destinations où le tourisme classique est en difficulté depuis une dizaine d’années ; situation assez paradoxale au regard du dynamisme de ce secteur d’activité dans la région.
ISSN: 1779-0980

hal-01624756
https://hal.archives-ouvertes.fr/hal-01624756
DOI : 10.4000/etudescaribeennes.5262

Éditeur(s) : HAL CCSD
Résumé : International audience
The French ministry of education introduced in 2005 the « organized returning of knowledge » (ROC) in the French baccalauréat as a tool to render more efficient the mathematical education at the end of secondary school. This article is based on an analysis of the ROC of the 2006 Antilles-Guyane baccalauréat, by the anthropological approach to didactics, which leads to the construction of its mathematical site. Through this analysis, some features of the ROC are discussed, such as its consistency (including from the view point of the institution) and the transparency of this evaluation.
L’introduction des restitutions organisées de connaissances (ROC) dans les épreuves du baccalauréat, à partir de 2005, est une réponse de l’institution à la volonté de rendre plus efficace l’enseignement en cycle terminal. Cet article s’appuie sur l’analyse de la ROC du sujet Antilles Guyane session 2006 par une approche anthropologique en proposant la construction de son site mathématique. Au travers de cet exemple sont interrogées certaines caractéristiques du concept ROC comme sa cohérence (notamment institutionnelle) et la transparence de cette évaluation.
Annales de didactique et de sciences cognitives

hal-01530860
https://hal.univ-antilles.fr/hal-01530860

Éditeur(s) : HAL CCSD
Résumé : International audience
The Amerindian genetic heritage is extremely poor in the French Antilles (Martinique and Guadeloupe archipelago). However, the early and important valorisation of the cultural Amerindian legacies has played a role, since the beginning of the 20th century, in the local expression of a specific cultural identity, distinct from the French national one. The absence of declared Amerindian descendants has for a part supported this strong valorisation. Unlike the African heritages, the Amerindian legacies were not linked to a painful and socially sensitive memory. However, before the last decades, the deep social integration of those legacies was limited by the progress of the identity building process. Nowadays, the identity discourse centered on "Antillanité" and "Créolité" notions allows the progressive disappearance of those bottlenecks and authorizes the transformation of those Amerindian legacies in French Antillean heritage elements socially recognised.
L'héritage amérindien est extrêmement faible du point de vue génétique dans les Antilles françaises. Cependant, sa valorisation importante et précoce a implicitement joué un rôle particulier dans l'expression d'une identité locale distincte de l'identité nationale française. Cette forte valorisation a sans doute été favorisée par le fait qu'en l'absence de descendants déclarés, l'histoire amérindienne, pour l'essentiel détachée du phénomène colonial, n'était liée à aucune mémoire douloureuse. Cependant, avant les dernières décennies, la place faite à cet héritage ne pouvait être que limitée du fait même de l'état de la pensée identitaire. Aujourd'hui, avec le développement d'un discours centré sur les notions de créolité et d'antillanité, les sources de ce blocage sont en train de céder petit à petit. Nous assistons ainsi à la transformation de cet héritage en un des éléments reconnus du patrimoine antillais.
Outre-Mers

Droits : info:eu-repo/semantics/OpenAccess
hal-01020219
https://hal.univ-antilles.fr/hal-01020219
https://hal.univ-antilles.fr/hal-01020219/document
https://hal.univ-antilles.fr/hal-01020219/file/De_l_archA_ologie_prA_colombienne_au_patrimoine.pdf

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : This paper presents French historical sources and references about Tobago collected in the Libraries and Archives of Martinique and the record of two archaeological missions sent from Martinique to Tobago in the 1990’s. French contributions to the history of Tobago, published or not, gives light on the French speaking protestant Walloons who settled in the island during the 17th century. In addition the author shows the links between Dutch and French Huguenot families in the West Indies in spite of the French State.
Cet article tente la recension des sources et de la bibliographie de l’histoire de Tobago en langue française dans les fonds des Archives et des Bibliothèques de la Martinique et rappelle les missions archéologiques martiniquaises envoyées dans cette île au cours des années 1990. Les travaux français éclairent le rôle joué au XVIIe siècle par les Wallons, protestants de langue française, dans la colonisation de Tobago. L’auteur montre ensuite les liens tissés aux Antilles entre les familles hollandaises et huguenotes, malgré les persécutions de l’Etat français.
Tobago

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.1032
http://journals.openedition.org/etudescaribeennes/1032

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
BACKGROUND:Dengue fever is the most important arboviral infection that affects humans, particularly in tropical and subtropical regions. Here, we provide the first comprehensive overview of the severity of dengue epidemics in French Guiana.METHODOLOGY/PRINCIPAL FINDINGS:We monitored hospitalized cases between 2008 and 2013. Detailed clinical features and biological parameters were collected on a daily basis from all cases. Among the 1,356 cases, 216 (16%) were classified according to the WHO 2009 classification as dengue without warning signs (WS), 926 (68%) were classified as dengue with WS and 214 (16%) were classified as severe dengue. The severity rates were similar between the three major epidemics that occurred during the study period, whereas the hospitalization rate was highest in 2013. Fluid accumulation, aspartate aminotransferase (ASAT) counts>193 IU/L and platelet counts<75,000 cells/mm3 were associated with dengue severity.CONCLUSIONS/SIGNIFICANCE:Our findings provide a recent epidemiological description of the severity of dengue epidemics in French Guiana. These results highlight the potential impacts and consequences of implementing the WHO 2009 classification on hospital activity. Future studies should include virological and immunological investigations of well-documented serum samples
ISSN: 1932-6203

inserm-01481447
http://www.hal.inserm.fr/inserm-01481447
http://www.hal.inserm.fr/inserm-01481447/document
http://www.hal.inserm.fr/inserm-01481447/file/2017%2C%20Flamand%20-%20Epidemiological%20assessment%20of%20the%20severity%20of%20dengue%20epidemics%20in%20French%20Guiana.pdf
DOI : 10.1371/journal.pone.0172267.t003

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
BACKGROUND: The insecticide chlordecone was extensively used in the French West Indies to control banana root borer. Its persistence in soils has led to the widespread pollution of the environment, and human beings are still exposed to this chemical. Chlordecone has been shown to impair neurological and behavioural functions in rodents when exposed gestationally or neonatally. OBJECTIVES: The aim of the study was to evaluate the impact of prenatal and postnatal exposure to chlordecone on the cognitive, visual, and motor development of 7-month-old infants from Guadeloupe. METHODS: Infants were tested at 7 months (n=153). Visual recognition memory and processing speed were assessed with the Fagan Tests of Infant Intelligence (FTII), visual acuity with the Teller Acuity Card, and fine motor development with the Brunet-Lezine. Samples of cord blood and breast milk at 3 months (n=88) were analyzed for chlordecone concentrations. Postnatal exposure was determined through breast feeding and frequency of contaminated food consumption by the infants. RESULTS: Cord chlordecone concentrations in tertiles were associated with reduced novelty preference on the FTII in the highly exposed group (β=-0.19, p=0.02). Postnatal exposure through contaminated food consumption was marginally related to reduced novelty preference (β=-0.14, p=0.07), and longer processing speed (β=0.16, p=0.07). Detectable levels of chlordecone in cord blood were associated with higher risk of obtaining low scores on the fine motor development scale (OR=1.25, p<0.01). CONCLUSION: These results suggest that pre- and postnatal low chronic exposure to chlordecone is associated with negative effects on cognitive and motor development during infancy.
ISSN: 0013-9351

hal-00875939
https://hal.archives-ouvertes.fr/hal-00875939
DOI : 10.1016/j.envres.2012.07.006
PUBMED : 22910562

Éditeur(s) : Amer Geophysical Union
Résumé : On November 21, 2004, a magnitude 6.3 earthquake occurred offshore, 10 km south of Les Saintes archipelago in Guadeloupe (French West Indies). There were more than 30000 aftershocks recorded in the following two years, most of them at shallow depth near the islands of the archipelago. The main shock and its main aftershock of February 14, 2005 (M-w = 5.8) ruptured a NE-dipping normal fault (Roseau fault), mapped and identified as active from high-resolution bathymetric data a few years before. This fault belongs to an arc-parallel en echelon fault system that follows the inner edge of the northern part of the Lesser Antilles arc, accommodating the sinistral component of oblique convergence between the North American and Caribbean plates. The distribution of aftershocks and damage (destruction and landslides) are consistent with the main fault plane location and attitude. The slip model of the main shock, obtained by inverting jointly global broadband and local strong motion records, is characterized by two main slip zones located 5 to 10 km to the SE and NW of the hypocenter. The main shock is shown to have increased the Coulomb stress at the tips of the ruptured plane by more than 4 bars where most of the aftershocks occurred, implying that failures on fault system were mainly promoted by static stress changes. The earthquake also had an effect on volcanic activity since the Boiling Lake in Dominica drained twice, probably as a result of the extensional strain induced by the earthquake and its main aftershock.
Journal Of Geophysical Research-solid Earth (0148-0227) (Amer Geophysical Union), 2011-10 , Vol. 116 , N. B10301 , P. 1-25

Droits : Copyright 2011 by the American Geophysical Union.
http://archimer.ifremer.fr/doc/00200/31099/29511.pdf
DOI:10.1029/2011JB008310
http://archimer.ifremer.fr/doc/00200/31099/

Éditeur(s) : HAL CCSD
Résumé : The social change which takes place in the French West Indies after the Second World War ensues from a historical interactive process. It occurs between 1946 and 1961, within the frame of the new dynamic fostered in the aftermath of the war. Here we refer to the new political status of Department, the outbreak of social conflicts during the process of decolonization, the public policies and the planning of “the economic and social development” of the overseas departments. The dynamic also includes the population growth with the birth of a new generation- from the sociological point of view. The aforementioned interaction instils the new type of society emerging in the French West Indies since the 1960’s, without drastically changing their colonial social structure. This transformation named “Departmentalization” seems paradoxical because it will generate “modern” social frustrations, while maintaining existing frustrations that stemmed from the plantation society. This process led to the transition from a slave society to a consumer society. It allows us to understand the persistence of a latent social unrest in these departments, in spite of the overall significant improvement of the living conditions during the early twentieth century.
La transformation sociale des Antilles françaises qui se produit après la Seconde Guerre mondiale résulte d’un processus interactif historique. Celui-ci se produit entre 1946 et 1961 autour des nouvelles dynamiques de l’après-guerre. Il s’agit du statut départemental, de la décolonisation avec l’explosion des conflits sociaux, de la politique publique de « développement économique et social » avec la planification dans les départements d’outre-mer, et de l’accroissement démographique avec l’apparition d’une nouvelle génération « sociologique ». C’est précisément cette interaction qui est à l’origine du nouveau type de société qui émerge aux Antilles à partir des années 1960 sans pour autant que leur structure sociale coloniale ne soit bouleversée. Cette construction qui prend le nom commun de « Départementalisation » est paradoxale car elle va générer des frustrations sociales « modernes », tout en maintenant des frustrations anciennes issues de la société de plantation. En induisant ainsi le passage d’un monde d’ « habitation » à un monde de consommation, cette construction permet de comprendre un peu mieux, le maintien, au début du XXIe siècle, d’un malaise social latent dans ces départements en dépit d’une amélioration sensible et générale des conditions de vie.
https://hal.archives-ouvertes.fr/tel-01675708

Droits : info:eu-repo/semantics/OpenAccess
tel-01675708
https://hal.archives-ouvertes.fr/tel-01675708
https://hal.archives-ouvertes.fr/tel-01675708/document
https://hal.archives-ouvertes.fr/tel-01675708/file/D%C3%A9colonisation%20et%20changement%20social%20aux%20Antilles%20fran%C3%A7aises%20%281946-1961%29%20-%20Ma%C3%ABl%20LAVENAIRE%202017.pdf

Éditeur(s) : HAL CCSD Lippincott, Williams & Wilkins
Résumé : International audience
The aim of the study was to investigate the impact of first-line combined antiretroviral therapy (cART) regimen on the course of CD8 + T-cell counts in human immunodeficiency virus (HIV)-infected patients. A retrospective observational study conducted on the French DAT'AIDS Cohort of HIV-infected patients. We selected 605 patients initiating a first-line cART between 2002 and 2009, and which achieved a sustained undetectable HIV plasma viral load (pVL) for at least 12 months without cART modification. The evolution of CD8 + T-cell counts according to cART regimen was assessed. CD8 + T-cell counts were assessed in 572 patients treated with 2NRTIs+1PI/r (n= 297), 2NRTIs+1NNRTI (n= 207) and 3NRTIs (n= 68). In multivariate analysis, after 12 months of follow-up, the 3NRTIs regimen was associated with a significantly smaller decrease of CD8 + T-cell count compared with NNRTI-containing regimens (–10.2 cells/mL in 3NRTIs vs –105.1 cells/mL; P=0.02) but not compared with PI-containing regimens (10.2 vs –60.9 cells/mL; P=0.21). After 24 months, the 3NRTIs regimen was associated with a smaller decrease of CD8 + T-cell count and % compared with PI/r-and NNRTI-containing regimens (0.2 in 3NRTIs vs –9.9 with PI/r-regimens, P=0.001, and vs –11.1 with NNRTI-regimens, p < 0.0001). A focus analysis on 11 patients treated with an INSTI-containing cART regimen during the study period showed after 12 months of follow-up, a median decrease of CD8 + T-cell count of –155 [inter quartile range: –302; –22] cells/mL. Our data highlight the fact that cART regimens have differential effects on CD8 pool down regulation. Abbreviations: cART = combined antiretroviral therapy, HIV = human immunodeficiency virus, INSTI = integrase strand transfer inhibitor, NNRTI = non-nucleotide reverse transcriptase inhibitor, NRTI = nucleotide reverse transcriptase inhibitor, PI/r = Ritonavir-boosted protease inhibitor, pVL = plasma viral load.
ISSN: 0025-7974

inserm-01408002
http://www.hal.inserm.fr/inserm-01408002
http://www.hal.inserm.fr/inserm-01408002/document
http://www.hal.inserm.fr/inserm-01408002/file/2016%2C%20Poizot-Martin%20-%20First-line%20cART%20regimen%20impacts%20the%20course%20of%20CD8%2B%20T-cell%20counts%20in%20HIV-infected%20patients.pdf
DOI : 10.1097/MD.0000000000005087

Éditeur(s) : HAL CCSD National Institute of Environmental Health Sciences (NIEHS) National Institute of Environmental Health Sciences
Résumé : International audience
Long-term exposure to persistent pollutants with hormonal properties (endocrine-disrupting chemicals, EDCs) may contribute to the risk of prostate cancer (PCa). However, epidemiological evidence remains limited. We investigated the relationship between PCa and plasma concentrations of universally widespread pollutants, in particular p,p'-dichlorodiphenyl dichloroethene (DDE) and the non-dioxin like polychlorinated biphenyl congener 153 (PCB153). We evaluated before treatment 576 men with newly diagnosed PCa and 655 controls in Guadeloupe (French West Indies). Exposure was analyzed according to case-control status. Associations were assessed by unconditional logistic regression analysis, controlling for confounding factors. Missing data were handled by multiple imputation. We estimated a significant positive association between DDE and PCa (adjusted odds ratio [OR] 1.53; 95% CI 1.02, 2.30 for the highest versus lowest quintile of exposure; PTrend = 0.01). PCB153 was inversely associated with PCa (OR 0.30; 95% CI 0.19, 0.47 for the highest versus lowest quintile of exposure values; PTrend < 0.001). Also, PCB153 was more strongly associated to low-grade than high grade PCa. Associations of PCa with DDE and PCB153 were in opposite directions. This may reflect differences in the mechanisms of action of these EDCs, and although our findings need to be replicated in other populations, they are consistent with complex effects of EDCs on human health.
ISSN: 0091-6765

hal-01118553
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01118553
DOI : 10.1289/ehp.1408407
PUBMED : 25493337

Éditeur(s) : HAL CCSD WB Saunders
Résumé : International audience
OBJECTIVE: We hypothesized that, in Human Immunodeficiency Virus and Hepatitis C Virus (HIV/HCV) co-infected patients who did not respond to peg-interferon and ribavirin, a maintenance therapy with peg-interferon could induce fibrosis regression. METHODS: This was a randomized study with two parallel groups. HIV/HCV co-infected patients received peg-interferon α-2a at 180 μg/week or remained on observation for 96 weeks. The primary endpoint was the percentage of patients who experienced a decrease of at least one point in their Metavir fibrosis score between initial and final liver biopsies. Secondary endpoints included plasma fibrosis markers at week 96, occurrence of HCV-related complications, and survival. RESULTS: A total of 52 patients were randomized (peg-interferon: 25; control: 27) including 18 with cirrhosis. The median (interquartile range) age was 44 (40-46) years, and 69% were male. A total of 64% had ALT levels >1.5 normal values, and the CD4 cell count was 391 (296-537) cells/mm(3); 67% of patients had HIV RNA <200 copies/mL at entry. The main endpoint was assessed in 41 patients. Response rates were 3/20 (15%) and 4/21 (19%) in the peg-interferon and control groups, respectively (p = 0.99). There was no significant difference between peg-interferon and control groups on plasma fibrosis markers at the final visit. Severe liver-related complications were observed in 2 and 5 patients in peg-interferon and control groups, respectively. Three deaths were observed, all in the control group. CONCLUSIONS: A maintenance therapy with peg-interferon α-2a over 96 weeks in HIV/HCV co-infected patients, who were non-responders to HCV treatment, did not change liver fibrosis. ClinicalTrials.gov Identifier: NCT00122616.
ISSN: 0163-4453

hal-00875067
https://hal.archives-ouvertes.fr/hal-00875067
DOI : 10.1016/j.jinf.2013.05.007
PUBMED : 23800784

Éditeur(s) : HAL CCSD
Résumé : International audience
Over the past decade, much attention has been devoted to the development of forest biomass estimation methods at a stand scale, leading to the establishment of allometric models (Chave et al., 2014). These allometric equations use a unique wood specific gravity value (WSG) per species, but neglect the within tree variations of WSG found by others (Wiemann & Williamson, 1989).The main objectives of this study are (1) to illustrate the diversity of radial (from pith to bark) and longitudinal (from bottom to top) patterns of WSG variation within and between species, (2) to highlight different trends of WSG radial variations and the possible misinterpretations of these trends due to the effect of heartwood and (3) to link these variations and patterns to the successional status of the species (from pioneer to sciaphilic species).We sampled 33 small trees (10 Wood sciences underpinning tropical ecology and management. International closing symposium of the XYLAREDD project.
Tervuren, Belgium

hal-01188894
https://hal-sde.archives-ouvertes.fr/hal-01188894

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
INTRODUCTION:The frequency, the clinical characteristics, and the prognosis of dengue is highly variable. Dengue fever is associated with a range of neurological manifestations. The objective of the present study was to determine the incidence of neurological signs and their predictive factors using data from cases of dengue seen and followed in Cayenne Hospital during the Dengue 2 epidemic in 2013.METHODS:In 2013, a longitudinal study using data from all cases of dengue seen in Cayenne hospital was collected. Medical records used a standardized form to collect demographic information, clinical signs and biological results and the date at which they were present. The analysis used Cox proportional modeling to obtain adjusted Hazard ratios.RESULTS:A total of 1574 patients were included 221 of whom developed central nervous system signs. These signs were spontaneously resolutive. There were 9298person days of follow-up and the overall incidence rate for central nervous system signs was 2.37 per 100 person-days. The variables independently associated with central nervous system anomalies were headache, Adjusted Hazard ratio (AHR) = 1.9(95%CI = 1.4-2.6), bleeding AHR = 2 ((95%CI = 1.3-3.1), P = 0.001, abdominal pain AHR = 1.9 ((95%CI = 1.4-2.6), P<0.001, aches AHR = 2.1 ((95%CI = 1.5-2.9), P<0.001, and fatigue AHR = 1.5 ((95%CI = 1.3-1.7), P<0.001.DISCUSSION:Overall, the present study suggests that neurological signs of dengue are not exceptional even in patients without the most severe features of dengue. These manifestations were spontaneously resolutive. Here it was not possible to distinguish between encephalitis or encephalopathy. Further studies would require more in depth exploration of the patients.
ISSN: 1932-6203

inserm-01421218
http://www.hal.inserm.fr/inserm-01421218
http://www.hal.inserm.fr/inserm-01421218/document
http://www.hal.inserm.fr/inserm-01421218/file/2016%2C%20Djossou%20-%20Incidence%20and%20Predictive%20Factors%20of%20Central%20Nervous%20System%20Dysfunction%20in%20Patients%20Consulting.pdf
DOI : 10.1371/journal.pone.0150828.t003

Éditeur(s) : [s.n.]
Résumé : (Funding) Funded in part by the University of Florida, the Florida Heritage Project of the State University Libraries of Florida, the Institute for Museum and Library Services, and the U.S. Department of Education's TICFIA granting program.
Colombia
Guyana
Suriname
French Guiana
Panama
Venezuela
Grenada
Trinidad and Tobago
Netherlands Antilles
Aruba

Droits : This item is presumed to be in the public domain. The University of Florida George A. Smathers Libraries respect the intellectual property rights of others and do not claim any copyright interest in this item. Users of this work have responsibility for determining copyright status prior to reusing, publishing or reproducing this item for purposes other than what is allowed by fair use or other copyright exemptions. Any reuse of this item in excess of fair use or other copyright exemptions may require permission of the copyright holder. The Smathers Libraries would like to learn more about this item and invite individuals or organizations to contact Digital Services (UFDC@uflib.ufl.edu) with any additional information they can provide.
002357416
ALW1859
http://ufdc.ufl.edu/UF00066664/00001

Résumé : In the French West Indies islands, the transfer of chlordecone (kepone) from treated grounds towards the marine environment has been proved since the beginning of 2000s. In 2008, a maximal residue limit (MRL) was set at 20 µg / kg wet weight in fish and seafood, and therefore intensified the concern about the risks of high human exposure to the pesticide due to the consumption of contaminated marine products. To answer this concern, several sampling cruises were carried by public authorities and by Ifremer in order to analyze the contamination of the fish fauna around the Guadeloupe island. The data collected within these surveys improved our knowledge on the characteristics of the contamination of fish fauna and allowed to assess the distribution of this contamination in relation with optional geographical plans of the marine area around the Guadeloupe island. Further, this study was completed by an assessment of the fishery activity in areas which are the more exposed to the chlordecone contamination, taking into account data from a fishery observatory which has been set up in the archipelago since 2007. The results allow to precise two main characteristics of distribution of the contamination: its spatial and specific dimensions. About the spatial aspect, contamination of the fish fauna is centred on marine areas which are closely downstream contaminated watersheds. Concerning the marine fauna, two species groups are particularly exposed: the very coastal ones, particularly those living at or close to the mouth of rivers, and crustaceans wherever they live. Among fishes, the most contaminated species belong to many various groups which are present in the very coastal belt, more or less regularly. Lastly, this study provided orders of magnitude on the relative part of the fishery activity around the archipelagos for which the contamination is of great concern.
Aux Antilles, l’existence d’un transfert de la molécule de chlordécone des sols traités vers le milieu marin est avérée depuis le début des années 2000. L’établissement d’une limite maximale de résidus à 20 µg/kg pf pour tous les produits marins en 2008 y a intensifié la préoccupation vis-à-vis des risques d’exposition des populations humaines par les produits de la pêche. Pour répondre à cette préoccupation, depuis 2008, plusieurs campagnes d’échantillonnage ont été réalisées par les services de l’Etat (DAAF) et par l’Ifremer pour analyser la contamination de la faune halieutique autour de la Guadeloupe. Les données collectées de 2008 à 2011 par ces plans d’observation ont été utilisées pour actualiser les connaissances sur les caractéristiques de la contamination de la faune halieutique autour de la Guadeloupe, et analyser cette distribution en référence à différents schémas de segmentation du domaine marin. L’étude a été complétée par une analyse de l’activité halieutique dans les secteurs les plus sensibles à la contamination, à partir des données du système d’informations halieutiques déployé dans l’archipel depuis 2007. L’analyse a permis de préciser deux traits majeurs de cette distribution : sa dimension spatiale et son caractère spécifique. Sur le plan spatial, la contamination de la faune halieutique est centrée sur les espaces maritimes situées immédiatement en aval des bassins versants contenant des sols contaminés. Sur le plan faunistique, deux groupes apparaissent particulièrement sensibles, les espèces très côtières, en particulier celles fréquentant les embouchures des cours d’eau, et les crustacés, quelque soit leur milieu de vie. Chez les poissons, parmi les espèces contaminées, on trouve un large cortège d’espèces fréquentant plus ou moins régulièrement la bande littorale. Enfin, l’étude a permis de fournir des ordres de grandeur sur la part de l’activité halieutique de l’archipel directement concernée par cette pollution.

Droits : 2013 Ifremer
http://archimer.ifremer.fr/doc/00136/24762/22840.pdf
http://archimer.ifremer.fr/doc/00136/24762/

Résumé : The maritime fisheries and mariculture guidance law passed in 1997 specifies that with the perspective of renegotiation of the common fisheries policy in 2002, a report on the special conditions of inshore fisheries be drawn up by the Government. To do so, the Minister of Agriculture and Fisheries entrusted this task to three experts, who are the authors of this report. In accordance with their remit, the situation of fisheries in territorial waters and estuaries of metropolitan France and the four DOM overseas departments ( counties) was examined, in the framework of meetings with professional fishermen, administrations, elected officials and scientific organisations. The first part situates fishing activities in coastal areas within the overall context of French fisheries. The second part provides a detailed report for each seafront (Channel, Atlantic, Mediterranean, West Indies, French Guyana and Reunion Island) on the regulatory framework, fleets, stocks, uses of resources and vulnerable areas of interest for fisheries. The report then analyses the competition within fisheries and with other activities (recreational fishing, extraction of aggregates, tourism, etc.). After these observations, the authors make ten proposals to improve the conditions under which coastal or inshore fisheries are practiced.
La loi d'orientation sur la pêche maritime et les cultures marines votée en 1997 précise que dans la perspective de la renégociation de la politique commune des pêches en 2002, un rapport sur les conditions particulières de l'exercice de la pêche dans la bande côtière sera établi par le Gouvernement. Pour y satisfaire, le Ministre de l'Agriculture et de la Pêche en a confié l'élaboration à trois experts, les auteurs du présent rapport. Conformément à la lettre de mission, la situation de la pêche dans les eaux territoriales et estuaires du territoire métropolitain et des quatre départements d'Outre-Mer a été examinée dans le cadre de rencontres avec les professionnels, les administrations, les élus, les organismes scientifiques. Une première partie permet de situer les activités halieutiques en zone côtière dans le contexte global de la pêche française. La seconde partie est un bilan détaillé par façade (Manche, Atlantique, Méditerranée, Antilles, Guyane, Réunion) du cadre réglementaire, des flottilles, des ressources, des usages de la ressource et des zones sensibles d'intérêt halieutiques. Le rapport analyse ensuite les compétitions au sein de la pêche et avec d'autres activités (pêche récréative, extractions de granulats, tourisme,...). A l'issue de ces différents constats, les auteurs font dix propositions pour améliorer les conditions d'exercice de la pêche en zone côtière.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/2000/rapport-1200.pdf
http://archimer.ifremer.fr/doc/00000/1200/

Résumé : For several years the fishermen of the West Indies have directed their activities towards new fishing grounds, notably the bathyales zones adjacent to island plateaux up to approximately 1000 metres in depth. Explorations earned out since 1989 have shown that diverse crustacean populations could be exploited. However, populations and exploitable stocks arc not well known. The use of crustaceans traps as a fishing technique permits the capture of shellfish, shrimps and prawns of which at least six species could have commercial interest. The main objective of this work is do draw up an inventory of the principal commercial species as well as the accompanying species belonging to the subordres Decapoda macrura, anomura, brachyura, and to the orders Isopoda and Amphipoda. It is intended for fishermen and other socio-professionals of the fishing industry. It should enable them to identify and name these previously unexploited varieties of crustacea to facilitate their sale in local markets.
Depuis quelques années, des pécheurs antillais orientent leurs activités vers de nouveaux secteurs de pèche, notamment les zones bathyales adjacentes aux plateaux insulaires, jusque vers 1000 mètres de profondeur. Des campagnes exploratoires menées depuis 1989. on montré que diverses populations carcinologiques pouvaient l'aire l'objet d'une exploitation. Toutefois, populations et stocks exploitables ne sont pas bien connus. L'emploi du casier comme technique de pêche, permet la capture de crustacés: crevettes et langoustines, dont au moins 6 espèces peuvent avoir un intérêt commercial. Ce travail nomenclatural a pour premier objectif de dresser l'inventaire ces principales espèces commerciales ainsi que des espèces accompagnatrices appartenant aux infra-ordres des Décapodes macroures, anomoures, brachyoures et aux ordres des Isopodes et des Amphipodes. Il est destine aux pécheurs et aux autres personnes des catégories socioprofessionnelles de la filière pêche. II devrait leur permettre d'identifier et de nommer ces produits nouveaux pour faciliter leur vente sur les marchés locaux.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1993/rapport-992.pdf
http://archimer.ifremer.fr/doc/00000/992/

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
BACKGROUND: African Americans with head and neck squamous cell carcinoma (HNSCC) have a lower survival rate than whites. This study investigated the functional importance of ancestry-informative single-nucleotide polymorphisms (SNPs) in HNSCC and also examined the effect of functionally important genetic elements on racial disparities in HNSCC survival. METHODS: Ancestry-informative SNPs, RNA sequencing, methylation, and copy number variation data for 316 oral cavity and laryngeal cancer patients were analyzed across 178 DNA repair genes. The results of expression quantitative trait locus (eQTL) analyses were also replicated with a Gene Expression Omnibus (GEO) data set. The effects of eQTLs on overall survival (OS) and disease-free survival (DFS) were evaluated. RESULTS: Five ancestry-related SNPs were identified as cis-eQTLs in the DNA polymerase beta (POLB) gene (false discovery rate [FDR]<0.01). The homozygous/heterozygous genotypes containing the African allele showed higher POLB expression than the homozygous white allele genotype (P<.001). A replication study using a GEO data set validated all 5 eQTLs and also showed a statistically significant difference in POLB expression based on genetic ancestry (P=.002). An association was observed between these eQTLs and OS (P<.037; FDR<0.0363) as well as DFS (P=.018 to.0629; FDR<0.079) for oral cavity and laryngeal cancer patients treated with platinum-based chemotherapy and/or radiotherapy. Genotypes containing the African allele were associated with poor OS/DFS in comparison with homozygous genotypes harboring the white allele. CONCLUSIONS: Analyses show that ancestry-related alleles could act as eQTLs in HNSCC and support the association of ancestry-related genetic factors with survival disparities in patients diagnosed with oral cavity and laryngeal cancer. (C) 2016 American Cancer Society.
ISSN: 0008-543X

hal-01519253
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01519253
DOI : 10.1002/cncr.30457
PUBMED : 27906459

Éditeur(s) : HAL CCSD Dipartamento di Scienze della Terra, Università degli Studi di Modena
Résumé : International audience
The aim or this paper is to give an overall view of the natural hazards and risks affecting the French West Indies. These are mainly connected with hurricanes, volcanic eruptions and earthquakes which have caused several deaths and seriously weakened the local economy during the last three centuries. First of all the geological and geographical conditions which determine the natural predisposition of the French West Indies to geophysical and atmospheric hazards are described. Then the risk for the population is taken into account, both in terms of' the direct effects of the above mentioned hazards and of the side-effects, that is tidal waves, floods and mass movements. Finally the economic and social impact of natural disasters on the French West Indies and the difficulties arising in risk mitigation are shown.
Lo scopo di questo lavoro è di fornire un quadro generale dei rischi naturali che interessano le Antille Francese. Questi sono principalmente connessi con uragani, eruzioni vulcaniche e terremoti che, nel corso degli ultirni tre secoli hanno causato parecchi decessi e seriamente indebolito la economia locale. Vengono dapprima descritte le condizioni geologiche e geografiche che determinano la naturale predisposizione delle Antille Francese a minacche di tipo sia endogeno che esogeno. Viene poi considerato il rischio per la.popolazione, sia in termiini di effetti diretti dei fenomeni sopra citati che in termini di effetti marginali dovuti allo sviluppo di marernotti, alluvioni e frane. Infine viene considerato l’impatto sul tessuto sociale ed economico dei disastri di origine naturale nelle Antille Francese e le difficoltà che insorgono nella mitigazione del rischio.
The Erasmus 93-94 Programme in Geomorphology : Intensive Course in the French Antilles and Student Mobility

Droits : info:eu-repo/semantics/OpenAccess
ISBN : 88-900094-0-3
hal-01191892
https://hal.archives-ouvertes.fr/hal-01191892
https://hal.archives-ouvertes.fr/hal-01191892/document
https://hal.archives-ouvertes.fr/hal-01191892/file/D%27Ercole%201995%20-%20Natural%20hazards%20in%20the%20French%20West%20Indies.pdf