Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The dating of alluvial landforms by cosmogenic nuclides requires distinguishing the pre-deposition inheritance from the post-deposition history of the clasts in the studied marker. Moreover, estimating catchment-scale erosion rates from the concentrations of cosmogenic nuclides in active alluvia requires a good knowledge of the local/regional relationships between rock exhumation and transport through space and time. This is still poorly known for timescales of tens of thousand years. In order to document the evolution of clast exhumation and transport rates through time, we analyze in situ 10Be concentrations in boulders and cobbles from hillslopes to outlet of an arid mountainous catchment located in Gobi-Altay, Mongolia, strongly affected by global climatic changes during the Pleistocene-Holocene period. Samples were collected on bedrock, abandoned alluvial deposits, active colluvia and alluvia. Our results show a large 10Be scattering in the active river bed, consistent with a low and discontinuous catchment erosion rate dominated by mass wasting and fluvial incision. On the contrary, pre-exposure signal within abandoned terraces is much more homogeneous, consistent with climatic pulses responsible of strong erosional events on hillslopes and rapid fluvial transport. These results show that exhumation/transport processes at the catchment scale vary in style and intensity through time as a consequence of climatic oscillations. The occurrence of abrupt climatic changes during short periods of time recorded by 10Be concentrations in abandoned alluvia raise questions about the temporal applicability of catchment erosion rates derived from cosmogenic nuclide concentrations measured in sediments of active rivers. On the other hand, strong and short erosion events limit and homogenize the pre-exposure 10Be signal in associated deposits like debris-flows, making them particularly suitable markers for dating in active tectonic and paleoclimatic studies.
ISSN: 0169-555X

hal-00626702
https://hal.archives-ouvertes.fr/hal-00626702
https://hal.archives-ouvertes.fr/hal-00626702/document
https://hal.archives-ouvertes.fr/hal-00626702/file/GEOMOR-2485R1_corrected.pdf
DOI : 10.1016/j.geomorph.2011.07.023

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Nitrogen (N) transfer from legume trees to associated crops is a key factor for the N economy of low-input agroforestry systems. In this work, we presented a new approach to estimate N transfer based on the 15N content of root exudates and N released by root turnover of the donor plant (Gliricidia sepium) and the temporal change of the 15N content of the receiver plant (Dichanthium aristatum). The study was carried out in greenhouse using two isotopic methods: 15N leaf feeding (LF) and the natural 15N abundance (NA). Measurements of exudate 15N were made at several dates before and after tree pruning. A time-dependent box model was devised to quantify N transfer in time and to make comparisons between the isotopic methods. In NA, although tree roots and exudates presented a similar 15N signature before tree pruning, exudates were strongly depleted in 15N after pruning. In LF, exudates were always depleted in 15N in relation to tree roots. Hence, the current assumption used in N transfer studies concerning the equal 15N/14N distribution in tissues of the donor plant and in its excreted N was not confirmed in our study. Before pruning, N transfer functioned as a two-N-source system (soil N and exudates N) and both isotopic methods provided similar estimates: 11–12% for LF and 10–15% for NA. Calculations performed with the model indicated that N transfer occurred with small or nil fractionation of 15N in exudates. After pruning, there was a third N source associated with N released from tree root turnover. During this period, the isotopic signature of the receiver plant showed a transient state due to the progressive decrease of 15N content of that N source. The amount of N derived from the tree represented 65% of the total N content of the grass at the end of the experiments.
ISSN: 1161-0301

hal-01082183
https://hal-agroparistech.archives-ouvertes.fr/hal-01082183
DOI : 10.1016/j.eja.2007.03.003

Éditeur(s) : HAL CCSD
Résumé : Patagonia is well known for spectacular occurrences of a variety of glacial-derived landforms and deposits and for a long history of ancient glaciations. In this paper, we first review the diverse evidence that demonstrates the development of glacial-related sedimentary units within the Central Patagonian Cordillera since 7 Ma. Well preserved glacial landforrns at the top surface of mesetas on both sides of the Lago General Carrera-Buenos Aires are described: the Meseta Guenguel to the north, and the volcanic Meseta del Lago Buenos Aires to the south. The latter meseta corresponds to a 3 Ma old, morphologically inverted paleo-piedmont, based on Ar/Ar dates of the uppermost lava flows. It shows evidence of glacier advances to the NE direction. Over a distance of 20 km, glacial landforms observed by remote sensing data and digital elevation model define glacial tongues that were fed by the Cordillera reliefs to the west. These lobes are now beheaded from their westward sources along a morpho-structural corridor that bounds the Meseta del Lago Buenos Aires to the west. These remnants can be correlated with the oldest glacial landforms recognized north of Lago General Carrera-Buenos Aires, on the Meseta Guenguel that form the Chipanque moraine system. From these features it is concluded that the glacial drainage network of Central Patagonia has been strongly modified following relief inversion in response to erosion processes and to tectonic causes. Changes occurred after 3 Ma, from a smooth piedmont surface covered by an extensive ice mantle ending with ample glacial lobes, to the current series of deeply incised glacial valleys such as the Lago General Carrera-Buenos Aires depression. These new data bear important constraints on the history and development of the first glaciations in southern South America.
ANDEAN GEOLOGY

hal-00512682
https://hal.archives-ouvertes.fr/hal-00512682

Éditeur(s) : HAL CCSD Springer
Résumé : The analysis of three different regions of the South- Pyrenean fold-and-thrust belt reveals that during the Tertiary compression the hydrological system was compartmentalised in time and space. During the early-middle Eocene, when the thrust front affected marine soft-sediments in the Ainsa basin, the thrust fault zones were dominated by formation fluids derived from Eocene marine waters trapped in the underlying Eocene marls, although influences of meteoric waters were also present. During the middle-late Eocene, when the thrust front emplaced marine rocks over continental redbeds in the eastern Catalan basin (L'Escala thrust), the thrust fault zones were dominated by meteoric fluids. These fluids flowed preferentially along these faults, draining laterally the meteoric fluids and acting as barriers hindering their flowing towards more external parts of the belt. During the Oligocene, the most external part of the fold-and-thrust belt in the eastern Catalan basin developed on top of a salt detachment horizon. The thrust front affected continental materials of late Eocene-Oligocene age. At this moment, the thrusts were conduits for meteoric fluids arriving from the surface and also for evolved meteoric fluids migrating over short distance upwards after being in contact with the underlying evaporitic beds. Most of the fractures show a similar sequence of microfractures. Microfractures of stage 1 formed when the sediment was poorly lithified. Microfractures of stage 2 represent the main episode of vein formation which developed when a progressive induration of the host sediment occurred. During microfracture stage 3, formed in an extensional regime, the host sediment was more indurated. The repetition of this sequence of microfractures in different fracture generations of the same outcrop indicates that the sediment induration was restricted to the vicinity of the vein. Away from the veins, the sediment remained poorly lithified during the entire deformation cycle. Calcite cement within the host rock precipitated later than the syn-compressive veins, when the sediment was more indurated. Elemental geochemistry and stable isotopes of the calcite veins indicates that early generation of microfractures is infilled by local fluids (either marine or meteoric), whereas external fluids (meteoric or evolved meteoric) infilled the main compressive stage of microfractures. The hot temperature of these fluids (157°C to 183°C in the Atiart-Arro example) indicates their circulation through deep parts of the thrust belt. The progressive increase of the 87Sr/86Sr ratio through time is due to the progressive uplift, exposure and erosion of the internal Pyrenean Axial Zone.
Thrust belts and foreland basins, from fold kinematics to hydrocarbon systems

hal-00408001
https://hal.archives-ouvertes.fr/hal-00408001
DOI : 10.1007/978-3-540-69426-7_5

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Spinel (± plagioclase) peridotite xenoliths from the Tallante and Los Perez volcanic centres in the eastern Betics (SE Spain) range from depleted (clinopyroxene-poor) harzburgites to fertile (clinopyroxene-rich) lherzolites and orthopyroxene-free wehrlites. Significantly, only one harzburgite, which is depleted in heavy rare earth elements (HREE), retains the imprint of ca. 20% ancient melting of an original garnet lherzolite source. In contrast, REE abundances of other harzburgites and lherzolites from the eastern Betics have been increased by melt-rock reaction. The whole-rock and mineral compositions of these mantle rocks are largely controlled by three types of modal metasomatism: 1) common clinopyroxene-orthopyroxene addition and olivine consumption which increased FeOt, SiO2 and Al2O3, and decreased MgO compared to the refractory melting products; 2) subordinate orthopyroxene dissolution and precipitation of clinopyroxene and olivine, which led to higher FeOt and MgO and lower SiO2 than in common (orthopyroxene-rich) lherzolites; and 3) rare orthopyroxene consumption and olivine addition that caused higher FeOt and lower SiO2 compared to the original melting residues. These mineral modal and major element variations have been produced mostly by interactions with relatively FeOt-rich/SiO2-poor melts, likely derived from a peridotite-pyroxenite lithospheric mantle with a highly heterogeneous isotopic composition. Melting of the lithospheric mantle in the western Mediterranean was triggered by upwelling of the asthenosphere induced by back-arc extension in the Late Oligocene-Early Miocene. Trapping of small fractions of exotic melts in whole-rocks — likely the parental magmas of Miocene back-arc dykes that intruded the Betic crust — caused local disequilibrium between the trace element signatures and Pb isotopic compositions of clinopyroxene and whole-rock. Subsequent interaction with SiO2-undersaturated magmas, similar to the parental melts of the Pliocene alkali basalts that host the xenoliths, promoted orthopyroxene consumption and clinopyroxene-olivine enrichment at locations close to magma conduits, and finally generated orthopyroxene-free wehrlites. This event constitutes the last episode of the Cenozoic magmatic evolution of the westernmost Mediterranean which is recorded in the mantle xenoliths from the eastern Betics.
ISSN: 0024-4937

hal-01553092
https://hal.archives-ouvertes.fr/hal-01553092
DOI : 10.1016/j.lithos.2016.12.011

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Sickle cell anaemia (SCA) is the most frequent genetic haemoglobinopathy, which exhibits a highly variable clinical course characterized by hyper-coagulable and pro-inflammatory states, as well as endothelial dysfunction. Extracellular microvesicles are released into biological fluids and play a role in modifying the functional phenotype of target cells. We hypothesized that potential differences in plasma-derived extracellular microvesicles (EV) function and cargo from SCA patients may underlie divergent clinical trajectories. Plasma EV from SCA patients with mild, intermediate and severe clinical disease course were isolated, and primary endothelial cell cultures were exposed. Endothelial cell activation, monocyte adhesion, barrier disruption and exosome cargo (microRNA microarrays) were assessed. EV disrupted the endothelial barrier and induced expression of adhesion molecules and monocyte adhesion in a SCA severity-dependent manner compared to healthy children. Microarray approaches identified a restricted signature of exosomal microRNAs that readily distinguished severe from mild SCA, as well as from healthy children. The microRNA candidates were further validated using quantitative real time polymerase chain reaction assays, and revealed putative gene targets. Circulating exosomal microRNAs may play important roles in predicting the clinical course of SCA, and in delineation of individually tailored, mechanistically-based clinical treatment approaches of SCA patients in the near future.
ISSN: 0007-1048

hal-01668328
https://hal.univ-antilles.fr/hal-01668328
DOI : 10.1111/bjh.14104

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Field and petrostructural investigations in the Central Mauritanides provide new precisions on the polyorogenic character of the nappe edifice of this belt. The upper structural unit exposed in the Gaoua area includes anatectic gneisses and high-grade metasediments affected by medium temperature, high-pressure metamorphism and cut by granitoids. They represent a basement unconformably overlain by a monometamorphic cover, the Gaoua Group, of assumed lower Paleozoic age. Late Paleozoic regional metamorphism of metapelites from this cover is characterized by pyrophyllite-kyanite-chloritoid assemblages equilibrated at T around 420 degrees C and P = 1 GPa. In the lower structural unit exposed in the south around Boufkerine-Farkaka, metapelites of the Gadel Group display slightly retrogressed garnet-kyanite-staurolite-rutile assemblages that equilibrated at T around 600 degrees C and P >= 1.2 GPa before the intrusion of 639 Ma old plutons. The Gadel Group locally overlies in unconformity polycyclic gneisses. This continental assemblage represents an outboard terrane inserted between two monocyclic greenschist facies terranes: remnants of oceanic lithosphere in the east and arc-derived metasediments and metavolcanics cut by 670 Ma old calc-alkaline plutons in the west. All units have been involved in late Paleozoic nappes emplaced to the east above the West African craton and its late Neoproterozoic to Cambro-ordovician cover. Though an east-directed vergence is locally recorded in the Neoproterozoic units, most early E-W trending stretching and mineral lineations are synchronous with greenschist facies metamorphism developed during the Late Paleozoic and roughly coeval with the Applachian nappe system.
ISSN: 0899-5362

hal-00424501
https://hal.archives-ouvertes.fr/hal-00424501
DOI : 10.1016/j.jafrearsci.2008.09.004

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
The nature and extent of the regional lithosphere-asthenosphere interaction beneath Ireland and Britain remains unclear. Although it has been established that ancient Caledonian signatures pervade the lithosphere, tertiary structure related to the Iceland plume has been inferred to dominate the asthenosphere. To address this apparent contradiction in the literature, we image the 3-D lithospheric and deeper upper-mantle structure beneath Ireland via non-linear, iterative joint teleseismic-gravity inversion using data from the ISLE (Irish Seismic Lithospheric Experiment), ISUME (Irish Seismic Upper Mantle Experiment) and GRACE (Gravity Recovery and Climate Experiment) experiments. The inversion combines teleseismic relative arrival time residuals with the GRACE long wavelength satellite derived gravity anomaly by assuming a depth-dependent quasilinear velocity-density relationship. We argue that anomalies imaged at lithospheric depths probably reflect compositional contrasts, either due to terrane accretion associated with Iapetus Ocean closure, frozen decompressional melt that was generated by plate stretching during the opening of the north Atlantic Ocean, frozen Iceland plume related magmatic intrusions, or a combination thereof. The continuation of the anomalous structure across the lithosphere-asthenosphere boundary is interpreted as possibly reflecting sub-lithospheric small-scale convection initiated by the lithospheric compositional contrasts. Our hypothesis thus reconciles the disparity which exists between lithospheric and asthenospheric structure beneath this region of the north Atlantic rifted margin.
ISSN: 0956-540X

hal-00617815
https://hal.archives-ouvertes.fr/hal-00617815
DOI : 10.1111/j.1365-246X.2011.04921.x

Éditeur(s) : HAL CCSD Geological Society of America
Résumé : International audience
The post-rift denudation history of high-elevation divergent continentalmargins is central to deciphering source-to-sink systems acrosssuch margins and to unraveling their topographic evolution. We performed40Ar-39Ar dating of supergene K-Mn oxides from supergenemanganese ore deposits in order to constrain the age of in situ formedlaterites on both the lowland and highland sides of the Western GhatsEscarpment of Peninsular India. Documentation of laterites as oldas 53 Ma on the highland and 47 Ma at the foot of the escarpmentshows that the escarpment stabilized before 47 Ma (possibly 60 Ma).The topographic setting of the dated weathering mantles also constrainsdenudation of the lowland and the highland since ca. 50 Mato maximums of 5 m/m.y. and 15 m/m.y., respectively. Our resultschallenge denudation rates derived from apatite fission track thermochronologyby documenting the topography and relief longevityof the southwest Indian margin and its hinterland. The results precludelarge-magnitude uplift of Peninsular India after the Eocene,and more generally argue against late Neogene uplift and topographicrejuvenation of continental shields.
ISSN: 0091-7613

ird-01419633
http://hal.ird.fr/ird-01419633
http://hal.ird.fr/ird-01419633/document
http://hal.ird.fr/ird-01419633/file/GEOLOGY-S-15-00851_HAL.pdf
DOI : 10.1130/G37303.1

Éditeur(s) : HAL CCSD
Résumé : International audience
Debris avalanches derived from the flanks of volcanic islands are among the largest on Earth. Debris avalanches are rare, catastrophic destabilizations that still keep geologists debating about the mechanisms that initiate them and make them travel huge runout distances. To shed light on the trigger of such destabilizations, we studied the inland scar of a debris avalanche deposit cropping out at Piton des Neiges, a dormant and eroded basaltic volcano of La Réunion Island. The avalanche deposit rests on a pile of 50-70 sill intrusions with a shallow northward dip, i.e. toward the sea. We measured the anisotropy of magnetic susceptibility in a transect across the uppermost sill of the pile in contact with the avalanche deposit. This transect reveals a strongly asymmetric magnetic fabric, consistent with a north-directed shear movement of the upper intrusion wall. This suggests that the upper sill induced a co-intrusive shear displacement of the volcano flank toward the sea. The upper sill margin in contact with the avalanche is striated, showing that this intrusion is older than the avalanche. Striae indicate a northward direction of avalanche runout. The upper sill margin also displays a magmatic lineation consistent with a magma flow in the intrusion toward the north. There is thus a striking kinematic consistency between the directions of intrusion propagation and avalanche runout, both oriented toward the sea. From the above results, we propose that repeated sill intrusions, such as observed on Piton des Neiges, increase the instability of a volcanic edifice. Each injection induces an incremental slip of the overlying rock mass, which may eventually end up into a landslide. Sill intrusions associated with seaward displacements of volcano flank, such as inferred for the April 2007 eruption of Piton de la Fournaise (also in La Réunion), should therefore be considered as a potential trigger of debris avalanches.
Fall meeting
San Francisco, United States

hal-01387002
http://hal.univ-reunion.fr/hal-01387002

Éditeur(s) : HAL CCSD Histochemical Society
Résumé : International audience
The galectin-4 protein is mostly expressed in the digestive tract and is associated with lipid raft stabilization, protein apical trafficking, wound healing, and inflammation. While most mammalian species, including humans, have a single Lgals4 gene, some mice have two paralogues: Lgals4 and Lgals6. So far, their significant similarities have hindered the analysis of their respective expression and function. We took advantage of two antibodies that discriminate between the galectin-4 and galectin-6 proteins to document their patterns of expression in the normal and the dextran sodium sulfate (DSS)-damaged digestive tract in the mouse. In the normal digestive tract, their pattern of expression from tongue to colon is quite similar, which suggests functional redundancy. However, the presence of galectin-4, but not galectin-6, in the lamina propria of the DSS-damaged colon, its association with luminal colonic bacteria, and differences in subcellular localization of these proteins suggest that they also have distinct roles in the normal and the damaged mouse digestive tract. Our results provide a rare example of ancestral and derived functions evolving after tandem gene duplication.
ISSN: 0022-1554

hal-01544764
https://hal.archives-ouvertes.fr/hal-01544764
DOI : 10.1369/0022155413478612

Éditeur(s) : HAL CCSD University of Szeged, Bolyai Institute
Résumé : International audience
We consider the semilinear heat equation in a boundeddomain of R^m. We prove the null controllability of the systemwith a finite number of constraints on the normal derivative, whenthe control acts on a bounded subset of the domain. First, weshow that the problem can be transformed into a null controllabilityproblem with constraint on the control, for a linear system.Then, we use an appropriate observability inequality to solve thelinearized problem. Finally, we prove the main result by means ofa fixed-point method.
ISSN: 1417-3875

hal-01679144
https://hal.archives-ouvertes.fr/hal-01679144
DOI : 10.14232/ejqtde.2012.1.95

Éditeur(s) : HAL CCSD
Résumé : International audience
Sedimentary basins, through the sedimentary successions and the nature of the deposits, reflect the geology of thearea from which the sediments were derived and thus provide valuable record of hinterland tectonism. As the collisionbetween the South China and the Indochina blocks (i.e. the Indosinian orogeny) is still the object of a numberof controversies regarding, for instance, its timing and the polarity of the subduction, the sedimentary basins associatedwith this mountain belt are likely to provide clues to reconstruct its geodynamic evolution. However, boththe Sam Nua Basin (located to the south of the inner zones of the Indosinian orogeny and the Song Ma ophiolites)and the Song Da Basin (located to the north of the inner zones), northern Vietnam, are still lacking importantinformation regarding the depositional environments and the ages of the main formations that they contain.Using sedimentological and dating analyses (foraminifers biostratigraphy and U-Pb dating on detrital zircon), weprovide a new stratigraphic framework for these basins and propose a geodynamic evolution of the present-daynorthern Vietnam.During the Early Triassic, the Sam Nua Basin was mainly supplied by volcaniclastic sediments originating froman active volcanic activity. Geochemical investigations, combined with sedimentological and structural analyses,support an arc-related setting for this magmatism. This magmatic arc resulted from the subduction of a south dippingoceanic slab that once separated the South China from the Indochina blocks. During the Middle to the LateTriassic, the Sam Nua Basin underwent erosion that lead to the formation of a major unconformity, termed theIndosinian unconformity. This unconformity is interpreted to result from the erosion of the Indosinian mountainbelt, built after the continental collision between the South China and the Indochina blocks. Later, during the LateTriassic, the Sam Nua Basin experienced the deposition of very coarse material, emplaced under continental settingand representing the product of the erosion of the Indosinian mountain belt.To the North, the Song Da Basin is characterized by strongly diachronous deposits over a basal unconformitydeveloped at the expense of volcanic and volcaniclastic deposits related to the Emeishan Large Igneous Province.The sedimentary succession indicates a foreland setting during the Early to the Middle Triassic, which contrastswith the commonly assumed rift setting for these sediments. Thus, the Song Da Basin documents the formation ofthe Indosinian thrust belt, located immediately to the South of the basin.
European Geosciences Union General Assembly 2017
Vienne, Austria

insu-01510331
https://hal-insu.archives-ouvertes.fr/insu-01510331

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Some epidemiological investigations have revealed that frequent consumption of well-done cooked meats and tobacco smoking are risk factors for breast cancer in women. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic aromatic amine that is formed in well-done cooked meat, and 4-aminobiphenyl (4-ABP) is an aromatic amine that arises in tobacco smoke and occurs as a contaminant in the atmosphere. Both compounds are rodent mammary carcinogens, and putative DNA adducts of PhIP and 4-ABP have been frequently detected, by immunohistochemistry (IHC) or (32)P-post-labeling methods, in mammary tissue of USA women. Because of these findings, PhIP and 4-ABP have been implicated as causal agents of human breast cancer. However, the biomarker data are controversial: both IHC and (32)P-post-labeling are non-selective screening methods and fail to provide confirmatory spectral data. Consequently, the identities of the lesions are equivocal. We employed a specific and sensitive liquid chromatography/mass spectrometry (MS) method, to screen tumor-adjacent normal mammary tissue for DNA adducts of PhIP and 4-ABP. Only 1 of 70 biopsy samples obtained from Minneapolis, Minnesota breast cancer patients contained a PhIP-DNA adduct. The level was three adducts per 10(9) nucleotides, a level that is 100-fold lower than the mean level of PhIP adducts reported by IHC or (32)P-post-labeling methods. The occurrence of 4-ABP-DNA adducts was nil in those same breast tissues. Our findings, derived from a specific mass spectrometry method, signify that PhIP and 4-ABP are not major DNA-damaging agents in mammary tissue of USA women and raise questions about the roles of these chemicals in breast cancer.
ISSN: 0143-3334

hal-00682453
https://hal.archives-ouvertes.fr/hal-00682453
DOI : 10.1093/carcin/bgr252
PUBMED : 22072616

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Several recent studies have documented that reactions between melt and crystal mush in primitive gabbroic rocks (via reactive porous flow) have an important control in the formation of the lower oceanic crust and the evolution of MORBs. In this context, olivine-rich rocks can form either by fractional crystallization of primitive melts or by open system reactive percolation of pre-existing (possibly mantle-derived) olivine matrix. To address this question, we performed in-situ trace element analyses (by LA-ICP-MS) of olivine from the Erro-Tobbio ophiolite Unit (Ligurian Alps), where mantle peridotites show gradational contacts with an hectometer-scale body of troctolites and plagioclase wehrlites, and both are cut by later decameter-wide lenses and dykes of olivine gabbros. Previous studies inferred that troctolites and olivine gabbros represent variably differentiated crystallization products from primitive MORB-type melts. Olivines in the three rock types (mantle peridotites, troctolites, olivine gabbros) exhibit distinct geochemical signature and well-defined elemental correlations. As expected, compatible elements (e.g. Ni) show the highest concentrations in peridotites (2580–2730 ppm), intermediate in troctolites (2050–2230 ppm) and lowest in gabbros (1355–1420 ppm), whereas moderate incompatible elements (e.g. Mn, Zn) show the opposite behaviour. By contrast, highly incompatible elements like Zr, Hf, Ti, HREE are variably enriched in olivines of troctolites, and the enrichment in absolute concentrations is coupled to development of significant HFSE/REE fractionation (ZrN/NdN up to 80). AFC modelling shows that such large ZrN/NdN ratios in olivines are consistent with a process of olivine assimilation and plagioclase crystallization at decreasing melt mass, in agreement with textural observations. In-situ trace element geochemistry of olivine, combined with microstructural investigations, thus appears a powerful tool to investigate reactive percolation and the origin of olivine-rich rocks in the lower oceanic crust.
ISSN: 0016-7037

hal-01419938
https://hal.archives-ouvertes.fr/hal-01419938
DOI : 10.1016/j.gca.2016.06.029

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Background Although the French eating model may differ from those of other countries, no studies to date have investigated dietary patterns in a wide age range of adults and at the national level. We aimed to identify dietary patterns (DP) of French adults and assess their associations with demographic, socio-economic and behavioural factors. Methods The present study included 2624 adults (1087 men, 1537 women) aged 18–79 years from the cross-sectional national French INCA2 dietary survey. Dietary data were collected using a 7-day estimated food record. Clusters of DP were derived using principal component analysis and clustering, conjointly. Age-adjusted logistic regression analyses were used to investigate the association between DP and correlates. Results Five DP were identified, namely ‘traditional’, ‘prudent’, ‘diversified’, ‘processed’ and ‘sandwiches’. Men were more likely to follow a traditional diet and women the ‘prudent’ pattern. Members of the ‘processed’ and ‘sandwiches’ patterns were younger compared to non-members. Healthier dietary patterns were overall positively associated with a higher socio-economic position, healthier behaviours (in terms of sedentary behaviours and smoking status) and lower body mass index. Under-reporting of energy intake, restrictive diet to lose weight and dietary supplement consumption were also related to specific DP, although differentially in men and women. Associations with contextual factors (i.e. household composition, agglomeration size and region) were also observed. Conclusions The identification of adults’ dietary patterns and associated behaviours (all modifiable) is important for the conceptualisation of multi-behavioural programs. The additional information on social and environmental correlates is also essential for targeting the most vulnerable population groups in the context of such public health interventions
ISSN: 0952-3871

hal-01299975
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01299975
DOI : 10.1111/jhn.12315
PUBMED : 25233099

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
The interpretation of coseismic surface deformation measurements through inversion techniques is of major importance to understand the mechanical behaviour of a seismic fault. Dense geodetic data sets in the vicinity of the ruptured fault provide unique constraints on detailed fault geometry and slip distribution at depth, making them complementary to seismological data. Bam earthquake (Mw 6.6, 2003 December 26) induced surface deformation has been precisely mapped by Envisat ASAR interferometry and by subpixel correlation techniques applied to Spot-5 and ASAR amplitude images. These oblique and horizontal estimations of deformation have been completed with one levelling profile along the main road crossing the rupture from west to east. We process these data (separately and jointly) in a two-step inversion technique, within the elastic half-space theory framework. Our objective is to determine the dislocation model at depth that satisfies simultaneously all the geodetic constraints. Also, we estimate the relative contribution of each geodetic data set to this inversion process.We first use a stochastic direct approach called neighbourhood algorithm in order to estimate the average characteristics of the rupture, and their relative uncertainty. Constraining in this way the geometry of the ruptured fault, we then linearize the inverse problem and compute the slip distribution on the fault using a standard weighted least-square technique, assuming the solution is smooth to some degree. At each step, we discuss the optimal models, their stability as well as the relative influence of each data set on the derived models parameters. Our preferred model reveals a shallow dislocation on a quasi-vertical fault, slightly dipping towards east. The slip vector has a strike-slip component as high as 2 m, while the dip-slip component seems negligible.However, the estimation of the resolution matrices emphasizes the fact that the details of deep fault slip distribution remain out of the scope of this ill-conditioned inverse problem. Yet, our preferred model suggests a main dislocation limited at depth between 1 and 6 km. By contrast, the aftershocks observed in the months following the earthquake are located just beneath the estimated main shock.
ISSN: 0956-540X

hal-00314173
https://hal.archives-ouvertes.fr/hal-00314173
https://hal.archives-ouvertes.fr/hal-00314173/document
https://hal.archives-ouvertes.fr/hal-00314173/file/GJI-2007-169-849-briole.pdf
DOI : 10.1111/j.1365-246X.2007.03358.x

Éditeur(s) : HAL CCSD
Résumé : International audience
This study assessed the usefulness of UV spectrophotometry for the monitoring of a yeast-based deoxygenation process proposed for ships' ballast water treatment to prevent the transfer of aquatic invasive species. Ten-day laboratory experiments using three treatment concentrations and different water types were conducted and resulted in complete oxygen depletion of treated waters. The treatment performance and quality of treated waters were determined by measuring the UV-visible absorbance spectra of water samples taken over time. Samples were also used for laboratory analysis of water quality properties. The UV absorbance spectra values were strongly correlated (r = 0.96) to yeast cell density in treated waters. The second-order derivative (D (2)) of the spectra varied greatly over time, and the spectrum profiles could be divided into two groups corresponding to the oxygenated and anoxic phases of the treatment. The D (2) value at 215 nm was strongly correlated (r = 0.94) to ammonia levels, which increased over time. The D (2) value at 225 nm was strongly correlated (r  extgreater 0.97) to DO concentration. Our results showed that UV spectrophotometry may provide a rapid assessment of the behavior and performance of the yeast bioreactor over time by quantifying (1) the density of yeast cells, (2) the time at which anoxic conditions were reached, and (3) a water quality index of the treated water related to the production of ammonia. We conclude that the rapidity of the technique confers a solid advantage over standard methods used for water quality analysis in laboratory and would permit the direct monitoring of the treatment performance on-board ships
Environmental Monitoring and Assessment

hal-01286253
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01286253
DOI : 10.1007/s10661-016-5209-3
PUBMED : 26944435

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
BACKGROUND AND AIMS: Infection by hepatitis C virus is a worldwide health problem. An inadequate Th2 cytokine response promotes the fibrosis-cirrhosis fate. Immune-modulating molecules favoring a Th2 profile, such as HLA-G molecules of the HLA class Ib family, may play a role in chronic hepatitis. HLA-G contributes to the escape of tumors, and their involvement in viral infections has been increasingly described. The aim of this work was to study the expression of HLA-G in the liver, its cellular source and its regulation in cases of chronic C hepatitis. METHODS: HLA-G cells in blocks of liver derived from patients infected with HCV were labeled by immunohistochemistry and enumerated. Double immunofluorescence allowed the identification of the cellular source. HLA-G secretion by a human mast cell line was quantified by ELISA after various stimulations. After treatment with IFN-α real-time PCR was performed to determine the kinetics of cytokine expression profiles, followed by heat map clustering analysis. RESULTS: The number of HLA-G + cells was significantly associated with the area of fibrosis. For the first time, we identify the HLA-G+ cells as being mast cells. HLA-G secretion was significantly induced in human mast cells stimulated by IL-10 or interferons of class I. The transcriptome of the secretome of this cell line stimulated by IFN-α revealed that i) the HLA-G gene is upregulated late, ii) T lymphocytes and NK cells are recruited. CONCLUSIONS: These findings suggest an autocrine loop in the genesis of HCV liver fibrosis, based on mast cells expressing HLA-G.
ISSN: 0168-8278

hal-00874106
https://hal.archives-ouvertes.fr/hal-00874106
https://hal.archives-ouvertes.fr/hal-00874106/document
https://hal.archives-ouvertes.fr/hal-00874106/file/Amiot-Expression-HLA-G-revised.pdf
DOI : 10.1016/j.jhep.2013.09.006

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Semi-Volatile Organic Compounds (SVOCs) are commonly present in dwellings and several are suspected of having effects on male reproductive function mediated by an endocrine disruption mode of action. To improve knowledge of the health impact of these compounds, cumulative toxicity indicators are needed. This work derives Benchmark Doses (BMD) and Relative Potency Factors (RPF) for SVOCs acting on the male reproductive system through the same mode of action. We included SVOCs fulfilling the following conditions: detection frequency (>10%) in French dwellings, availability of data on the mechanism/mode of action for male reproductive toxicity, and availability of comparable dose-response relationships. Of 58 SVOCs selected, 18 induce a decrease in serum testosterone levels. Six have sufficient and comparable data to derive BMDs based on 10 or 50% of the response. The SVOCs inducing the largest decrease in serum testosterone concentration are: for 10%, bisphenol A (BMD10= 7.72E-07 mg/kg bw/d; RPF10= 7033679); for 50%, benzo[a]pyrene (BMD50= 0.030 mg/kg bw/d; RPF50= 1630), and the one inducing the smallest one is benzyl butyl phthalate (RPF10 and RPF50= 0.095). This approach encompasses contaminants from diverse chemical families acting through similar modes of action, and makes possible a cumulative risk assessment in indoor environments. The main limitation remains the lack of comparable toxicological data.
ISSN: 0273-2300

hal-01237085
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01237085
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01237085/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01237085/file/Multiple%20exposures%20to%20indoor%20contaminants_accepted.pdf
DOI : 10.1016/j.yrtph.2015.11.017