Extrait de : Voyage a Surinam description des possessions néerlandaises dans la Guyane (Planche 4)
Siècle(s) traité(s) : 19
Droits : Domaine public
Permalien : http://www.manioc.org/images/GAD110610002i3
GAD110610002i3
GAD110610002i3

Éditeur(s) : Caribbean Volunteer Expeditions Caribbean Volunteer Expeditions ( Corning, NY )

Droits : All rights reserved by the source institution.

Éditeur(s) : HAL CCSD Landes Bioscience
Résumé : International audience
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
Autophagy

hal-00735751
https://hal.archives-ouvertes.fr/hal-00735751
PUBMED : 22966490

Éditeur(s) : HAL CCSD springer Link
Résumé : International audience
Experimental Astronomy

hal-01094521
https://hal.archives-ouvertes.fr/hal-01094521
BIBCODE : 2014ExA...tmp...41R
DOI : 10.1007/s10686-014-9383-4
ARXIV : 1310.0696

Éditeur(s) : Gauthier-villars
Résumé : Seismic, Seabeam, magnetic and gravimetrie surveys in the southern part of the N-Fiji basin were conducted during the SEAPSO LEG III Cruise. The active spreading axis was recognized between 17°30'S and 21°S. It consists of a continuous N-S Ridge cross-cut by transverse directions oriented N25 and N45. North of 17°30'S, the spreading System is more complex due to the existence of a possible triple junction located around 15° S. The eastern part of the N-Fiji basin, west of Viti Levu is mostly characterized by alternating highs and deeps (<4,000 m). This area must be regarded no more as a spreading center, but as complex boundary suffering transverse tectonics.
La mission SEAPSO III a permis de localiser une zone d'accrétion active, d'orientation méridienne et pratiquement continue entre 17°30'S et 21° S. Des accidents transverses, qui encadrent ou recoupent cette dorsale, s'orientent autour de deux directions principales N25 et N45. Au Nord de 17 30'S le système d'accrétion, beaucoup plus complexe, annonce la triple jonction reconnue aux alentours de 15" S. La partie orientale du bassin Nord-Fidjien (à l'Ouest de l'île de Viti Levu) est caractérisée par l'alternance de zones hautes et de dépressions dont certaines dépassent 4000 m de profondeur. Il s'agit d'une zone complexe de déformations liées à des accidents cisaillants transverses.
Comptes Rendus de l'Academie des Sciences Serie II (1251-8069) (Gauthier-villars), 1986-06 , Vol. 303 , N. 1 , P. 93-98

Droits : Académie des Sciences
http://archimer.ifremer.fr/doc/00184/29492/27835.pdf
http://archimer.ifremer.fr/doc/00184/29492/

Éditeur(s) : Elsevier
Résumé : Regardless of the degree of closure of a recirculation system, effluents are produced and replacement water is needed, which limits the possibility of locating a seawater production system away from the shoreline. At the Palavas Ifremer station, in the south of France, a High Rate Algal Pond (HRAP) was operated during several years to treat the effluent from a recirculating aquaculture system before reusing it. The effect of the HRAP-treated water on the recirculation system and on the fish was investigated and the optimal algae growing conditions were defined. The experiments were carried out in three rearing systems: one flow through, one recirculating and one recirculating with a HRAP. The water flow rate, temperature, pH and salinity conditions were similar in all systems. The effect of reusing the HRAP-treated water is very limited (1) on the functioning of the recirculation system and (2) on fish performance, but it allows a significant reduction of the dissolved inorganic nitrogen and phosphorus concentration in the rearing water. HRAP treatment reduced metal accumulation in muscle and liver of RAS fish, except for chromium and arsenic. All biomarkers presented no significant difference between systems, except for Superoxide Dismutase (SOD) and EROD, which showed a higher concentration in RAS and in both recirculating system respectively. (c) 2005 Elsevier B.V. All rights reserved.
Aquaculture (0044-8486) (Elsevier), 2006-03 , Vol. 252 , N. 1 , P. 92-101

Droits : 2005 Elsevier
http://archimer.ifremer.fr/doc/2006/publication-2306.pdf
DOI:10.1016/j.aquaculture.2005.11.053
http://archimer.ifremer.fr/doc/00000/2306/

Éditeur(s) : HAL CCSD Elsevier Masson
Résumé : International audience
ISSN: 1631-0691

hal-01083754
https://hal-agroparistech.archives-ouvertes.fr/hal-01083754
DOI : 10.1016/j.crvi.2009.01.006

Éditeur(s) : HAL CCSD European Geosciences Union
Résumé : International audience
The exchanges of carbon, water and energy between the atmosphere and the Amazon basin have global implications for the current and future climate. Here, the global atmospheric inversion system of the Monitoring of Atmospheric Composition and Climate (MACC) service is used to study the seasonal and interannual variations of biogenic CO 2 fluxes in Amazonia during the period 2002–2010. The system assimilated surface measurements of atmospheric CO 2 mole fractions made at more than 100 sites over the globe into an atmospheric transport model. The present study adds measurements from four surface stations located in tropical South America, a region poorly covered by CO 2 observations. The estimates of net ecosystem exchange (NEE) optimized by the inversion are compared to an independent estimate of NEE upscaled from eddy-covariance flux measurements in Amazonia. They are also qualitatively evaluated against reports on the seasonal and interannual variations of the land sink in South America from the scientific literature. We attempt at assessing the impact on NEE of the strong droughts in 2005 and 2010 (due to severe and longer-than-usual dry seasons) and the extreme rainfall conditions registered in 2009. The spatial variations of the seasonal and in-terannual variability of optimized NEE are also investigated. While the inversion supports the assumption of strong spatial heterogeneity of these variations, the results reveal critical limitations of the coarse-resolution transport model, the surface observation network in South America during the recent years and the present knowledge of modelling uncertainties in South America that prevent our inversion from capturing the seasonal patterns of fluxes across Amazonia. However, some patterns from the inversion seem consistent with the anomaly of moisture conditions in 2009.
ISSN: 1680-7316

hal-01557375
https://hal.univ-lorraine.fr/hal-01557375
https://hal.univ-lorraine.fr/hal-01557375/document
https://hal.univ-lorraine.fr/hal-01557375/file/acp-15-8423-2015.pdf
DOI : 10.5194/acp-15-8423-2015-supplement

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : While Amazonian forests are extraordinarily diverse, the abundance of trees is skewed strongly towards relatively few 'hyperdominant' species. In addition to their diversity, Amazonian trees are a key component of the global carbon cycle, assimilating and storing more carbon than any other ecosystem on Earth. Here we ask, using a unique data set of 530 forest plots, if the functions of storing and producing woody carbon are concentrated in a small number of tree species, whether the most abundant species also dominate carbon cycling, and whether dominant species are characterized by specific functional traits. We find that dominance of forest function is even more concentrated in a few species than is dominance of tree abundance, with only ≈1% of Amazon tree species responsible for 50% of carbon storage and productivity. Although those species that contribute most to biomass and productivity are often abundant, species maximum size is also influential, while the identity and ranking of dominant species varies by function and by region.
ISSN: 2041-1723

hal-01204225
https://hal.archives-ouvertes.fr/hal-01204225
DOI : 10.1038/ncomms7857
PRODINRA : 305614
PUBMED : 25919449

Éditeur(s) : HAL CCSD Wiley-VCH Verlag
Résumé : International audience
Deciphering the assembly history of the Milky Way is a formidable task, which becomes possible only if one can produce high-resolution chrono-chemo-kinematical maps of the Galaxy. Data from large-scale astrometric and spectroscopic surveys will soon provide us with a well-defined view of the current chemo-kinematical structure of the Milky Way, but will only enable a blurred view on the temporal sequence that led to the present-day Galaxy. As demonstrated by the (ongoing) exploitation of data from the pioneering photometric missions CoRoT, Kepler, and K2, asteroseismology provides the way forward: solar-like oscillating giants are excellent evolutionary clocks thanks to the availability of seismic constraints on their mass and to the tight age-initial-mass relation they adhere to. In this paper we identify five key outstanding questions relating to the formation and evolution of the Milky Way that will need precise and accurate ages for large samples of stars to be addressed, and we identify the requirements in terms of number of targets and the precision on the stellar properties that are needed to tackle such questions. By quantifying the asteroseismic yields expected from PLATO for red-giant stars, we demonstrate that these requirements are within the capabilities of the current instrument design, provided that observations are sufficiently long to identify the evolutionary state and allow robust and precise determination of acoustic-mode frequencies. This will allow us to harvest data of sufficient quality to reach a 10% precision in age. This is a fundamental pre-requisite to then reach the more ambitious goal of a similar level of accuracy, which will only be possible if we have to hand a careful appraisal of systematic uncertainties on age deriving from our limited understanding of stellar physics, a goal which conveniently falls within the main aims of PLATO's core science.
ISSN: 0004-6337

hal-01541393
https://hal.archives-ouvertes.fr/hal-01541393
ARXIV : 1706.3778
BIBCODE : 2017AN....338..644M
DOI : 10.1002/asna.201713385

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
New outcrops in the Sinis peninsula (Sardinia, Italy) allow a detailed description of the Messinian erosion surface. The correlation between outcrops, industrial seismic data and data collected offshore Oristano from a recent cruise permits reconstruction of the geometry of this surface from presently emerged interfluves to the deep canyons offshore, with: - onshore: an eroded karstic plateau presently cropping out over a 20 km × 5 km area. Well-preserved karst structures occur locally and can form several metres high reliefs. The southernmost edge of the plateau is limited by a cliff. The karstic plateau and the cliff are sealed by transgressive deposits of Pliocene age; - offshore, an interfluve zone with a mostly flat and low-angle dipping plateau, westward dissected by paleovalleys which were identified down to a depth of 2000 m. In the Oristano Gulf, Messinian paleovalleys were also identified. The Capo San Marco paleocliff was probably located on the edge of a canyon. Onshore, only one major erosion surface was identified, located at the top the Messinian sequence. Offshore, this surface extends down to the abyssal plain. The surface was emplaced above deposits related to the Terminal Carbonate Complex. This indicates that the marginal evaporites are older than the major drawdown of the Mediterranean sea-level. The major drawdown is related to the deposition of the deep evaporites.
ISSN: 0037-0738

hal-00407864
https://hal.archives-ouvertes.fr/hal-00407864
DOI : 10.1016/j.sedgeo.2008.06.005

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
ISSN: 0029-8549

hal-00524665
https://hal.archives-ouvertes.fr/hal-00524665

Éditeur(s) : HAL CCSD Wiley Open Access
Résumé : Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species' threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that support computation of a range of biodiversity indicators, is necessary to enable better understanding of historical declines and to project - and avert - future declines. We describe and assess a new database of more than 1.6 million samples from 78 countries representing over 28,000 species, collated from existing spatial comparisons of local-scale biodiversity exposed to different intensities and types of anthropogenic pressures, from terrestrial sites around the world. The database contains measurements taken in 208 (of 814) ecoregions, 13 (of 14) biomes, 25 (of 35) biodiversity hotspots and 16 (of 17) megadiverse countries. The database contains more than 1% of the total number of all species described, and more than 1% of the described species within many taxonomic groups - including flowering plants, gymnosperms, birds, mammals, reptiles, amphibians, beetles, lepidopterans and hymenopterans. The dataset, which is still being added to, is therefore already considerably larger and more representative than those used by previous quantitative models of biodiversity trends and responses. The database is being assembled as part of the PREDICTS project (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems - ). We make site-level summary data available alongside this article. The full database will be publicly available in 2015.
ISSN: 2045-7758

hal-01204216
https://hal.archives-ouvertes.fr/hal-01204216
DOI : 10.1002/ece3.1303
PRODINRA : 280886

Éditeur(s) : HAL CCSD AGU and the Geochemical Society
Résumé : International audience
Microbathymetry data, in situ observations, and sampling along the 13°20′N and 13°20′N oceanic core complexes (OCCs) reveal mechanisms of detachment fault denudation at the seafloor, links between tectonic extension and mass wasting, and expose the nature of corrugations, ubiquitous at OCCs. In the initial stages of detachment faulting and high-angle fault, scarps show extensive mass wasting that reduces their slope. Flexural rotation further lowers scarp slope, hinders mass wasting, resulting in morphologically complex chaotic terrain between the breakaway and the denuded corrugated surface. Extension and drag along the fault plane uplifts a wedge of hangingwall material (apron). The detachment surface emerges along a continuous moat that sheds rocks and covers it with unconsolidated rubble, while local slumping emplaces rubble ridges overlying corrugations. The detachment fault zone is a set of anostomosed slip planes, elongated in the along-extension direction. Slip planes bind fault rock bodies defining the corrugations observed in microbathymetry and sonar. Fault planes with extension-parallel stria are exposed along corrugation flanks, where the rubble cover is shed. Detachment fault rocks are primarily basalt fault breccia at 13°20′N OCC, and gabbro and peridotite at 13°30′N, demonstrating that brittle strain localization in shallow lithosphere form corrugations, regardless of lithologies in the detachment zone. Finally, faulting and volcanism dismember the 13°30′N OCC, with widespread present and past hydrothermal activity (Semenov fields), while the Irinovskoe hydrothermal field at the 13°20′N core complex suggests a magmatic source within the footwall. These results confirm the ubiquitous relationship between hydrothermal activity and oceanic detachment formation and evolution.
ISSN: 1525-2027

hal-01571973
https://hal.archives-ouvertes.fr/hal-01571973
https://hal.archives-ouvertes.fr/hal-01571973v2/document
https://hal.archives-ouvertes.fr/hal-01571973/file/Escart-n_et_al-2017-Geochemistry%2C_Geophysics%2C_Geosystems.pdf
DOI : 10.1002/2016GC006775

Éditeur(s) : HAL CCSD Elsevier
Résumé : Une approche par datations multiples a été menée sur les dépôts de sédiments de crue retrouvés dans les gorges du Gardon (Languedoc). Le plomb-210, le césium-137 et l’analyse géochimique des sédiments contaminés par les mines ont été utilisés pour reconstruire l’histoire des dépôts de crue. Cette approche a été combinée avec l’historique des crues du Gardon depuis 1890 pour affiner l’approche géochronologique. Au niveau de la cavité GG et de la terrasse GE les analyses ont permis d’illustrer les mécanismes d’érosion-redéposition pouvant perturber les séquences de sédiments. Les enregistrements des dépôts de sédiments de crue sont complets sur la terrasse GE située à 10 m au-dessus du lit mineur à partir de 1958, et incomplets auparavant. Sur la période 1880-1958, 25 crues ont eu un débit suffisant (>1450 m3/s) pour recouvrir la terrasse, alors que l’on recense seulement 5 à 6 crues depuis 1958 (pour un débit de submersion supérieur à 1700 m3/s). L’augmentation progressive du débit de submersion et la fréquence moindre d’inondation de la terrasse ont pu permettre sur la période récente la stabilisation de la couche de surface par la végétation et limiter l’érosion lors de crues importantes. Les enregistrements semblent complets dans la cavité GG située à 15 m au-dessus du lit mineur. La fréquence moindre de submersion à ce niveau plus élevé peut expliquer une meilleure stabilisation des dépôts de crue, rendus moins vulnérables à l’érosion. La datation au radiocarbone a été testée même si elle ne permet pas de dater avec précision les dépôts de crue des derniers siècles. Sur la terrasse GE, 80% des dates au carbone 14 sur charbon de bois sont beaucoup trop vieilles par rapport aux autres techniques de datation, ce qui peut s’expliquer par une remobilisation/déstockage de charbons de bois anciens. Les datations radiocarbone sur graines donnent de meilleurs résultats, car issues d’une production annuelle, plus facilement décomposable et moins sujette à des dépôts intermédiaires. Au final, il apparaît que la technique de datation par radiocarbone sur des charbons de bois retrouvés dans les séquences sédimentaires n’est pas fiable, alors qu’elle est la plus pratiquée en paléo-hydrologie. L’utilisation combinée du plomb-210, du césium-137, de l’analyse géochimique des sédiments et des informations sur les crues historiques a permis de discriminer et de dater les différents dépôts de crue de ce dernier siècle dans la cavité GG et la terrasse GE. / A multidating approach was carried out on slackwater flood deposits, preserved in valley side rock cave and terrace, of the Gardon River in Languedoc, southeast France. Lead-210, caesium-137, and geochemical analysis of mining-contaminated slackwater flood sediments have been used to reconstruct the history of these flood deposits. These age controls were combined with the continuous record of Gardon flow since 1890, and the combined records were then used to assign ages to slackwater deposits. The stratigraphic records of terrace GE and cave GG were excellent examples to illustrate the effects of erosion/preservation in a context of a progressively self-censoring, vertically accreting sequence. The sedimentary flood record of the terrace GE located at 10 m above the channel bed is complete for years post-1958 but incomplete before. During the 78-year period 1880-1958, 25 floods of a sufficient magnitude (> 1450 m3/s) have covered the terrace. Since 1958, however, the frequency of inundation of the deposits has been lower:only 5 or 6 floods in 52 years have been large enough to exceed the necessary threshold discharge (> 1700 m3/s). The progressive increase of threshold discharge and the reduced frequency of inundation at the terrace could allow stabilisation of the vegetation cover and improved protection against erosion from subsequent large magnitude flood events. The sedimentary flood record seems complete for cave GG located at 15 m above the channel bed. Here, the low frequency of events would have enabled a high degree of stabilisation of the sedimentary flood record, rendering the deposits less susceptible to erosion. Radiocarbon dating are used in this study and compared to the other dating techniques.Eighty percent of radiocarbon dates on charcoals were considerably older than those obtained by the other techniques in the terrace. On the other hand, radiocarbon dating on seeds provided better results. This discrepancy between radiocarbon dates on charcoal and seeds is explained by the nature of the dated material (permanent wood vs. annual production and resistance to degradation process). Finally, we showed in this study that although the most common dating technique used in paleoflood hydrology is radiocarbon dating, usually on charcoal preserved within slackwater flood sediments, this method did not permitus to define a coherent age model. Only the combined use of lead-210, caesium-137, and geochemical analysis of mining-contaminated sediments with the instrumental flood record can be applied to discriminate and date the recent slackwater deposits of the terrace GE and cave GG.
ISSN: 0169-555X

hal-01059669
https://hal.archives-ouvertes.fr/hal-01059669
https://hal.archives-ouvertes.fr/hal-01059669/document
https://hal.archives-ouvertes.fr/hal-01059669/file/ly2014-pub00040953.pdf
IRSTEA : PUB00040953

Éditeur(s) : HAL CCSD European Geosciences Union
Résumé : International audience
The seasonal climate drivers of the carbon cycle in tropical forests remain poorly known, although these forests account for more carbon assimilation and storage than any other terrestrial ecosystem. Based on a unique combination of seasonal pan-tropical data sets from 89 experimental sites (68 include aboveground wood productivity measurements and 35 litter productivity measurements), their associated canopy photosynthetic capacity (enhanced vegetation index, EVI) and climate, we ask how carbon assimilation and aboveground allocation are related to climate seasonality in tropical forests and how they interact in the seasonal carbon cycle. We found that canopy photosynthetic capacity seasonality responds positively to precipitation when rainfall is < 2000 mm yr(-1) (water-limited forests) and to radiation otherwise (light-limited forests). On the other hand, independent of climate limitations, wood productivity and litterfall are driven by seasonal variation in precipitation and evapotranspiration, respectively. Consequently, light-limited forests present an asynchronism between canopy photosynthetic capacity and wood productivity. First-order control by precipitation likely indicates a decrease in tropical forest productivity in a drier climate in water-limited forest, and in current light-limited forest with future rainfall < 2000 mm yr(-1).
ISSN: 1726-4170

hal-01557759
https://hal.univ-lorraine.fr/hal-01557759
https://hal.univ-lorraine.fr/hal-01557759/document
https://hal.univ-lorraine.fr/hal-01557759/file/bg-13-2537-2016.pdf
DOI : 10.5194/bg-13-2537-2016

Éditeur(s) : HAL CCSD Springer
Résumé : International audience
Diabetologia
Stockholm, Sweden

hal-01204766
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01204766
DOI : 10.1007/s00125-015-3687-4

Éditeur(s) : HAL CCSD Springer
Résumé : International audience
We present here a synthesis of the evolution of rifted continental margin systems in the Gulf of Aden. These margins are volcanic to the west of the Gulf of Aden, where they are influenced by the Afar hotspot, and non-volcanic east of longitude 46° E. The combined use of magnetics, gravity, seismic reflection, field observations (tectonic, stratigraphic and sedimentological) and oil well data allowed us to obtain better constraints on the timing of continental rifting and seafloor spreading. From the Permo-Triassic to the Oligocene, the Arabian-African plate was subject to distributed extension, probably due, at least from the Cretaceous, to tensile stresses related to the subduction of the Tethysian slab in the north. In Late Eocene-Early Oligocene, 34-33 Ma ago, rifting started to localise along the future area of continental breakup. Initially guided by the inherited basins, continental rifting then occurred synchronously over the entire gulf before becoming localised on the northern and southern borders of the inherited grabens, in the direction of the Afar hotspot. In the areas with non-volcanic margins (in the east), the faults marking the end of rifting trend parallel to the inherited grabens. Only the transfer faults cross-cut the inherited grabens, and some of these faults later developed into transform faults. The most important of these transform faults follow a Precambrian trend. Volcanic margins were formed in the west of the Gulf, up to the Guban graben in the southeast and as far as the southern boundary of the Bahlaf graben in the northeast. Seaward dipping reflectors can be observed on many oil industry seismic profiles. The influence of the hotspot during rifting was concentrated on the western part of the gulf. Therefore, it seems that the western domain was uplifted and eroded at the onset of rifting, while the eastern domain was characterised by more continuous sedimentation. The phase of distributed deformation was followed by a phase of strain localisation during the final rifting stage, just before formation of the Ocean-Continent Transition (OCT), in the most distal graben (DIM graben). About 20 Ma ago, at the time of the continental break-up, the emplacement of the OCT started in the east with exhumation of the subcontinental mantle. Farther west, the system was heated up by the strong influence of the Afar hotspot, which led to breakup with much less extension. In the Gulf of Aden (s.str), up to the Shukra El Sheik fracture zone, oceanic spreading started 17.6 Ma ago. West of this fracture zone, oceanic accretion started 10 Ma ago, and 2 Ma ago in the Gulf of Tadjoura. Post-rift deformation of the eastern margins of the Gulf of Aden can be seen in the distal and proximal domains. Indeed, the substantial post-rift uplift of these margins could be associated with either the continental break-up, or activity of the Afar hotspot and related volcanic/magmatic activity. Uplift of the northern proximal margin was still active (e.g. stepped beach rocks exposed at 60 m of 2 Ma; 30 m of 35,200 years; 10 and 2 m) and active volcanoes can be inferred at depths of between 70 and 200 km beneath the margin (at 5-10 km distance from the coast). On the distal margin, heat flow measurements show a high value that is associated with post-rift volcanic activity and the development of a volcano (with flows and sills) shortly after the formation of the OCT. The Afar hotspot is therefore important for several reasons. It allows the localisation of deformation along the Red Sea/Aden system and the rapid opening of the Gulf after the continental break-up; its influence also seems to persist during the post-rift period.
ISSN: 1866-7411

hal-01053089
https://hal.archives-ouvertes.fr/hal-01053089
DOI : 10.1007/s12517-011-0475-4

Éditeur(s) : HAL CCSD Wiley/Blackwell
Résumé : International audience
This article documents the addition of 512 microsatellite marker loci and nine pairs of Single Nucleotide Polymorphism (SNP) sequencing primers to the Molecular Ecology Resources Database. Loci were developed for the following species: Alcippe morrisonia morrisonia, Bashania fangiana, Bashania fargesii, Chaetodon vagabundus, Colletes floralis, Coluber constrictor flaviventris, Coptotermes gestroi, Crotophaga major, Cyprinella lutrensis, Danaus plexippus, Fagus grandifolia, Falco tinnunculus, Fletcherimyia fletcheri, Hydrilla verticillata, Laterallus jamaicensis coturniculus, Leavenworthia alabamica, Marmosops incanus, Miichthys miiuy, Nasua nasua, Noturus exilis, Odontesthes bonariensis, Quadrula fragosa, Pinctada maxima, Pseudaletia separata, Pseudoperonospora cubensis, Podocarpus elatus, Portunus trituberculatus, Rhagoletis cerasi, Rhinella schneideri, Sarracenia alata, Skeletonema marinoi, Sminthurus viridis, Syngnathus abaster, Uroteuthis (Photololigo) chinensis, Verticillium dahliae, Wasmannia auropunctata, and Zygochlamys patagonica. These loci were cross-tested on the following species: Chaetodon baronessa, Falco columbarius, Falco eleonorae, Falco naumanni, Falco peregrinus, Falco subbuteo, Didelphis aurita, Gracilinanus microtarsus, Marmosops paulensis, Monodelphis Americana, Odontesthes hatcheri, Podocarpus grayi, Podocarpus lawrencei, Podocarpus smithii, Portunus pelagicus, Syngnathus acus, Syngnathus typhle,Uroteuthis (Photololigo) edulis, Uroteuthis (Photololigo) duvauceli and Verticillium albo-atrum. This article also documents the addition of nine sequencing primer pairs and sixteen allele specific primers or probes for Oncorhynchus mykiss and Oncorhynchus tshawytscha; these primers and assays were cross-tested in both species.
ISSN: 1755-098X

hal-01094222
https://hal-agroparistech.archives-ouvertes.fr/hal-01094222
DOI : 10.1111/j.1755-0998.2010.02916.x

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
ObjectivesTo compare the efficacy, in current clinical practice, of ă first regimens containing abacavir with lamivudine (ABC/3TC) or ă tenofovir with emtricitabine (TDF/FTC) in patients with baseline viral ă load 100000 HIV-1 RNA copies/mL. ă MethodsUsing a prospective cohort, we selected all patients starting a ă first HIV regimen based either on ABC/3TC or on TDF/FTC. The propensity ă score (PS) method was used to limit the indication bias due to the ă observational nature of the data. Adjusting and weighting methods via PS ă were used to compare the effectiveness of a first regimen containing ă ABC/3TC or TDF/FTC. The primary outcome was treatment failure by month ă 12 (M12). ă ResultsOverall, 2781 patients started an antiretroviral (ARV) regimen ă with ABC/3TC or TDF/FTC each in combination with efavirenz, boosted ă atazanavir or boosted darunavir. Among the 2472 uncensored patients ă before M12, 962 (39%) had a baseline viral load 100000 copies/mL of ă whom 294 were in treatment failure at or before M12. Our analyses showed ă no difference between ABC/3TC and TDF/FTC in the risk of treatment ă failure at M12 in patients starting an ARV regimen with a high viral ă load (100000 copies/mL). ă ConclusionsUsing a large prospectively collected cohort of patients ă seeking care in France, we found no evidence that ABC/3TC based regimens ă led to more failures than TDF/FTC based ones in patients with high ă baseline viral loads.
ISSN: 1464-2662

hal-01482656
https://hal.archives-ouvertes.fr/hal-01482656
DOI : 10.1111/hiv.12306