Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
Collisional mountain belts grow as a consequence of continental plate convergence and eventuallydisappear under the combined effects of gravitational collapse and erosion. Using a decade ofGPS data, we show that the western Alps are currently characterized by zero horizontal velocityboundary conditions, offering the opportunity to investigate orogen evolution at the time ofcessation of plate convergence. We find no significant horizontal motion within the belt, but GPS andlevelling measurements independently show a regional pattern of uplift reaching ~2.5 mm/yr in thenorthwestern Alps. Unless a low viscosity crustal root under the northwestern Alps locally enhancesthe vertical response to surface unloading, the summed effects of isostatic responses to erosion andglaciation explain at most 60% of the observed uplift rates. Rock-uplift rates corrected from transientglacial isostatic adjustment contributions likely exceed erosion rates in the northwestern Alps. In theabsence of active convergence, the observed surface uplift must result from deep-seated processes.
ISSN: 2045-2322

hal-01357450
https://hal.archives-ouvertes.fr/hal-01357450
https://hal.archives-ouvertes.fr/hal-01357450/document
https://hal.archives-ouvertes.fr/hal-01357450/file/noquet2016.pdf
DOI : 10.1038/srep28404

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/00040/15136/12475.pdf
http://archimer.ifremer.fr/doc/00040/15136/

Éditeur(s) : Actes du 24ème congrès de la World Aquaculture Society, 17ème congrès de l'European Aquaculture Society, Torremolinos, Espagne. 24 - 28 mai 1993
Résumé : Ce document est un rapport de mission commun des 44 chercheurs du groupe IFREMER ayant participé au 2ème congrès mixte de la World Aquaculture Society et de l'European Aquaculture Society qui s'est tenu à Torremolinos, en Espagne, du 24 au 28 mai 1993.

Droits : 1993 Ifremer
http://archimer.ifremer.fr/doc/00021/13207/10259.pdf
http://archimer.ifremer.fr/doc/00021/13207/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
ISSN: 0264-3707

hal-00680683
https://hal-brgm.archives-ouvertes.fr/hal-00680683
DOI : 10.1016/j.jog.2011.11.010

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The eastern part of the Cordillera Occidental of Ecuador comprises thick buoyant oceanic plateaus associated with island-arc tholeiites and subduction-related calc-alkaline series, accreted to the Ecuadorian Continental Margin from Late Cretaceous to Eocene times. One of these plateau sequences, the Guaranda Oceanic Plateau is considered as remnant of the Caribbean–Colombian Oceanic Province (CCOP) accreted to the Ecuadorian Margin in the Maastrichtien. Samples studied in this paper were taken from four cross-sections through two arc-sequences in the northern part of the Cordillera Occidental of Ecuador, dated as (Río Cala) or ascribed to (Macuchi) the Late Cretaceous and one arc-like sequence in the Chogòn-Colonche Cordillera (Las Orquídeas). These three island-arcs can clearly be identified and rest conformably on the CCOP. In all four localities, basalts with abundant large clinopyroxene phenocrysts can be found, mimicking a picritic or ankaramitic facies. This mineralogical particularity, although not uncommon in island arc lavas, hints at a contribution of the CCOP in the genesis of these island arc rocks. The complete petrological and geochemical study of these rocks reveals that some have a primitive island-arc nature (MgO values range from 6 to 11 wt.%). Studied samples display marked Nb, Ta and Ti negative anomalies relative to the adjacent elements in the spidergrams characteristic of subduction-related magmatism. These rocks are LREE-enriched and their clinopyroxenes show a tholeiitic affinity (FeOT–TiO2 enrichment and CaO depletion from core to rim within a single crystal). The four sampled cross-sections through the island-arc sequences display homogeneous initial Nd, and Pb isotope ratios that suggest a unique mantellic source for these rocks resulting from the mixing of three components: an East-Pacific MORB end-member, an enriched pelagic sediment component, and a HIMU component carried by the CCOP. Indeed, the ankaramite and Mg-basalt sequences that form part of the Caribbean-Colombian Oceanic Plateau are radiogenically enriched in 206Pb/204Pb and 207Pb/204Pb and contain a HIMU component similar to that observed in the Gorgona basalts and Galápagos lavas. The subduction zone that generated the Late Cretaceous arcs occurred far from the continental margin, in an oceanic environment. This implies that no terrigenous detrital sediments interacted with the source at this period. Thus, the enriched component can only result from the melting of subducted pelagic sediments. We have thus defined the East-Pacific MORB, enriched (cherts, pelagic sediments) and HIMU components in an attempt to constrain and model the genesis of the studied island-arc magmatism, using a compilation of carefully selected isotopic data from literature according to rock age and paleogeographic location at the time of arc edification. Tripolar mixing models reveal that proportions of 12–15 wt.% of the HIMU component, 7–15 wt.% of the pelagic sediment end-member and 70–75 wt.% of an East-pacific MORB end-member are needed to explain the measured isotope ratios. These surprisingly high proportions of the HIMU/CCOP component could be explained by the young age of the oceanic plateau (5–15 Ma) during the Late Cretaceous arc emplacement. The CCOP, basement of these arc sequences, was probably still hot and easily assimilated at the island-arc lava source.
ISSN: 0895-9811

insu-00353692
https://hal-insu.archives-ouvertes.fr/insu-00353692
DOI : 10.1016/j.jsames.2008.06.003

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Subduction processes play a major role in plate tectonics and the subsequent geological evolution of Earth. This special issue focuses on ongoing research in subduction dynamics to a large extent (oceanic subduction, continental subduction, obduction…) for both past and active subduction zones and into mountain building processes and the early evolution of orogens. It puts together various approaches combining geophysics (imaging of subduction zones), petrology/geochemistry (metamorphic analysis of HP-UHP rocks, fluid geochemistry and magmatic signal, geochronology), seismology and geodesy (present-day evolution of subduction zones, active tectonics), structural geology (structure and evolution of mountain belts), and numerical modelling to provide a full spectrum of tools that can be used to constrain the nature and evolution of subduction processes and orogeny. Studies presented in this special issue range from the long-term (orogenic cycle) to short-term (seismic cycle).
ISSN: 0264-3707

insu-01287985
https://hal-insu.archives-ouvertes.fr/insu-01287985
https://hal-insu.archives-ouvertes.fr/insu-01287985/document
https://hal-insu.archives-ouvertes.fr/insu-01287985/file/rolland-2016.pdf
DOI : 10.1016/j.jog.2016.03.006

Éditeur(s) : HAL CCSD Météo et Climat
Résumé : International audience
Les risques hydrométéorologiques sont au coeur du programme de recherche HyMeX sur le cycle de l'eau en Méditerranée. HyMeX a pour ambition d'améliorer leur prévision, de mieux connaître leur variabilité à l'échelle pluriannuelle et de renseigner sur leur évolution, dans le contexte du changement climatique. À cette fin, deux campagnes de mesures dédiées à ces événements extrêmes (SOP1 : pluies intenses et crues rapides ; SOP2 : vents forts et formation d'eaux denses) sont organisées en Méditerranée nord-occidentale, entre septembre 2012 et mars 2013.
ISSN: 0026-1181

hal-00829760
https://hal.archives-ouvertes.fr/hal-00829760
DOI : 10.4267/2042/48793

Éditeur(s) : HAL CCSD BMJ Publishing Group
Résumé : International audience
BACKGROUND: Mutations in the leucine-rich-repeat kinase 2 (LRRK2) gene have been identified in families with autosomal dominant Parkinson's disease (ADPD), the most common of which is the p.G2019S substitution that has been found at varying frequencies worldwide. Because of the size of the LRRK2 gene, few studies have analysed the entire gene in large series of ADPD families. METHODS: We performed extensive mutation analyses of all 51 coding exons of the LRRK2 gene in index cases from 226 Parkinson's disease families compatible with autosomal dominant inheritance, mostly from France (n = 182) and North Africa (n = 14). RESULTS: We found 79 sequence variants, 29 of which were novel. Eight potentially or proven pathogenic mutations were found in 22 probands (9.7%). There were four novel amino acid substitutions that are potentially pathogenic (p.S52F, p.N363S, p.I810V, p.R1325Q) and two novel variants, p.H1216R and p.T1410M, that are probably not causative. The common p.G2019S mutation was identified in 13 probands (5.8%) including six from North Africa (43%). The known heterozygous p.R1441H and p.I1371V mutations were found in two probands each, and the p.E334K variant was identified in one single patient. Most potentially or proven pathogenic mutations were located in the functional domains of the Lrrk2 protein. CONCLUSION: This study leads us to conclude that LRRK2 mutations are a common cause of autosomal dominant Parkinson's disease in Europe and North Africa.
ISSN: 0022-2593

inserm-00529272
http://www.hal.inserm.fr/inserm-00529272
DOI : 10.1136/jmg.2008.062612
PUBMED : 19357115

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
Retreatment with pegylated interferon (peg-IFN) and ribavirin (RBV) results in poor sustained virological response (SVR) rates in human immunodeficiency virus (HIV)/hepatitis C virus (HCV)-coinfected patients. There are limited data regarding the use of telaprevir plus peg-IFN/RBV in this population. HIV type 1-infected patients who previously failed ≥12 weeks of peg-IFN/RBV for HCV genotype 1 coinfection were enrolled in a single-arm, phase 2 trial. Patients with cirrhosis and previous null response were excluded. Authorized antiretrovirals were tenofovir, emtricitabine, efavirenz, atazanavir, and raltegravir. All patients received peg-IFN alfa-2a (180 µg/week) plus RBV (1000-1200 mg/day) for 4 weeks, followed by telaprevir (750 mg or 1125 mg every 8 hours with efavirenz) plus peg-IFN/RBV for 12 weeks and peg-IFN/RBV for 32-56 weeks according to virological response at week 8. The primary endpoint was the SVR rate at 24 weeks after the end of treatment (SVR24). Sixty-nine patients started treatment; SVR24 was achieved in 55 (80% [95% confidence interval, 68%-88%). SVR24 was not influenced by baseline fibrosis stage, IL28B genotype, antiretroviral regimen, HCV subtype, CD4 cell count, previous response to HCV treatment, HCV RNA level, or HCV RNA decline at week 4. HCV treatment was discontinued for adverse events (AEs) in 20% of patients, including cutaneous (4%), psychiatric (4%), hematological (6%), and other AEs (6%). Peg-IFN or RBV dose reduction was required in 23% and 43% of patients, respectively. Seventy percent of patients required erythropoietin, blood transfusions, or RBV dose reduction for anemia. Two patients died during the study. No HIV breakthrough was observed. Despite a high discontinuation rate related to toxicity, a substantial proportion of treatment-experienced HIV-coinfected patients achieved SVR24 with a telaprevir-based regimen. Clinical Trials Registration. NCT01332955.
ISSN: 1058-4838

hal-01118447
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01118447
PUBMED : 25139963
DOI : 10.1093/cid/ciu659

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Syn-orogenic detachments in accretionary wedges make the exhumation of high-pressure and low-temperature metamorphic rocks possible with little erosion. The velocity of exhumation within the subduction channel or the accretionary complex, and thus the shape of P-T paths, depend upon the kinematic boundary conditions. A component of slab retreat tends to open the channel and facilitates the exhumation. We document the effect of slab retreat on the shape of P-T paths using the example of the Phyllite-Quartzite Nappe that has been exhumed below the Cretan syn-orogenic detachment during the Miocene in Crete and the Peloponnese. Data show a clear tendency toward colder conditions at peak pressure and during exhumation where the intensity of slab retreat is larger. This spatial evolution of P-T gradient is accompanied with an evolution from a partly coaxial regime below the Peloponnese section of the detachment toward a clearly non-coaxial regime in Crete.
ISSN: 0040-1951

insu-00411771
https://hal-insu.archives-ouvertes.fr/insu-00411771
https://hal-insu.archives-ouvertes.fr/insu-00411771/document
https://hal-insu.archives-ouvertes.fr/insu-00411771/file/Jolivet-Tectonophysics-2010.pdf
DOI : 10.1016/j.tecto.2009.10.002

Éditeur(s) : HAL CCSD
Résumé : International audience
The complexity of the Lesser Antilles vegetation must be linked to the variety of topographic features that influence the structure of some climatic parameters, particularly the rainfall. The above mentioned environmental factors influence a plurality of biotopes colonized by specific phytocenoses. Using survey transects of different minimal areas, we highlighted the specific, biocenotic, structural and architectural heterogeneity of the survey stations. This spatio-temporal differentiation of plant groupings is strongly guided by the activities of the successive human societies. These elements show that the anthropized vegetation of the Lesser Antilles represents a true laboratory for the study of plant succession using the synchronic approach.
ISSN: 2320-5407

hal-01376445
https://hal.univ-antilles.fr/hal-01376445
DOI : 10.21474/IJAR01/1322

Éditeur(s) : HAL CCSD
Résumé : International audience
Febrile illness is a common cause of attendance at emergency departments. The purpose of this study was to describe infectious aetiologies of fever in a tropical setting. We prospectively included 1443 febrile patients, all French Guiana residents, who presented at Cayenne Hospital emergency department. This report will propose an overview of aetiologies of febrile illness in French Guiana, and tropical diseases such as malaria and arbovirus infections are discussed. Almost 30% of fevers remained unexplained. Further prospective multicentre studies are warranted to improve the diagnosis of overlooked pathogens in French Guiana. Such studies would lead to conclusions of specific interest in the travel medicine field.
Transactions of the Royal Society of Tropical Medicine and Hygiene / Transactions of the Royal Society for Tropical Medicine and Hygiene

pasteur-00584097
https://hal-riip.archives-ouvertes.fr/pasteur-00584097
DOI : 10.1016/j.trstmh.2008.06.011
PUBMED : 18640694

Éditeur(s) : HAL CCSD American Geophysical Union (AGU)
Résumé : International audience
The objective of this study was to realize a three-dimensional (3-D) geological model of the deep basin structure of the Middle Durance region (of folds and faults) by integration of geological and geophysical data, and to evaluate its fault geometry and tectonic history. All of the available geophysical and geological data were compiled in three dimensions using the gOcad geomodeler. The geological and geophysical data were used to build a 3-D geological model of the Middle Durance region. The data on the 3-D geometry of fault surfaces and stratigraphic horizons and the thickness maps of the main stratigraphic units are supported by the 3-D geological model. We show that the Middle Durance Fault cannot be interpreted as a single fault plane that affected the entire Meso-Cenozoic sedimentary layers and the Paleozoic basement but as a listric segmented faulting system in sedimentary layers, rooted in Triassic evaporites and a normal block faulting system in the basement. This decoupling level in the Triassic layers reveals thin-skin deformation, formed by strong mechanical decoupling between the Mesozoic sedimentary cover and the Paleozoic basement. This study also confirms that the Provence geological structure has resulted mainly from Pyrenean deformation, which was partly reactivated by Alpine deformation. We demonstrate that the Middle Durance Fault Zone is a transfer fault that accommodates deformation of the sedimentary filling of the South-East Basin through modified fold geometry over a zone of 7 km to 8 km around the main segment of the fault zone.
ISSN: 0278-7407

hal-01172221
https://hal.archives-ouvertes.fr/hal-01172221
DOI : 10.1002/2014TC003749

Éditeur(s) : HAL CCSD John Libbey Eurotext
Résumé : International audience
Environmental health risk assessment is commonly used in France for risk management purposes. The Methodology section of the "Société française de santé environnement" (French Society for Environmental Health) seeks to improve the utility and implementation of risk assessment in France. An initial operational objective is to make a list of short-, intermediate- and long-term improvements. This inventory is based in part on the experience and expertise of society members in this area and in part on their analysis of "Science and Decisions: Advancing Risk Assessment" (National Research Council 2009). In this paper, the Society recommends modifications in the indications for and use of risk assessments, during each of the four stages of the process: hazard identification and dose-response assessment, exposure assessment, risk characterization, and results interpretation. Some may be implemented now, while others need consensus building or research because of gaps in knowledge. Environmental health risk assessment must be understood as a decision tool for risk management in situations of uncertainly. Thus, appropriate linkage is required between decision making and assessment, and between the methods and the expected results.
L'évaluation des risques sanitaires est fréquemment utilisée en France dans les processus de décision en santé environnementale. La section " Méthodologie d'évaluation des risques sanitaires " de la Société française de santé environnement (SFSE) s'est donnée pour objectif de proposer des éléments de réflexion et des outils méthodologiques en vue d'améliorer l'utilité et les pratiques de l'évaluation des risques sanitaires. Un premier objectif opérationnel est l'inventaire des améliorations possibles à court, moyen et long termes à apporter à la démarche et à son utilisation. Ce travail s'est fondé, d'une part, sur la pratique et l'expertise des membres de la section, et, d'autre part, sur une lecture critique du rapport " Science and Decisions : Advancing Risk Assessment " publié en 2009 par le National Research Council et portant également sur les évolutions de la démarche. Dans cet article, la section restitue les conclusions de cet inventaire critique et propose un certain nombre d'améliorations en termes d'indications et d'utilisations de l'évaluation des risques sanitaires pour chacune des quatre étapes : identification des dangers et relation dose-réponse ; évaluation de l'exposition ; caractérisation des risques ; et interprétation des résultats. Certaines recommandations peuvent être mises en oeuvre immédiatement ; d'autres, en préalable à leur mise en oeuvre, nécessitent un consensus ou encore de la recherche car les connaissances manquent. En conclusion, la section insiste sur le fait que l'évaluation des risques sanitaires doit être comprise comme une aide à la décision en situation d'incertitude ; l'articulation entre le contexte décisionnel et l'évaluation, sa méthodologie et les résultats attendus est donc primordiale.
ISSN: 1635-0421

ineris-00963325
https://hal-ineris.archives-ouvertes.fr/ineris-00963325
DOI : 10.1684/ers.2011.0435
INERIS : EN-2012-016

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : The area of forest plantations is increasing worldwide helping to meet timber demand and protect natural forests. However, with global change, monospecific plantations are increasingly vulnerable to abiotic and biotic disturbances. As an adaption measure we need to move to plantations that are more diverse in genotypes, species, and structure, with a design underpinned by science. TreeDivNet, a global network of tree diversity experiments, responds to this need by assessing the advantages and disadvantages of mixed species plantations. The network currently consists of 18 experiments, distributed over 36 sites and five ecoregions. With plantations 1-15 years old, TreeDivNet can already provide relevant data for forest policy and management. In this paper, we highlight some early results on the carbon sequestration and pest resistance potential of more diverse plantations. Finally, suggestions are made for new, innovative experiments in understudied regions to complement the existing network.
ISSN: 0044-7447

hal-01204232
https://hal.archives-ouvertes.fr/hal-01204232
DOI : 10.1007/s13280-015-0685-1
PRODINRA : 324368
PUBMED : 26264716

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
BACKGROUND: In the context of recent guidelines on invasive candidiasis (IC), how French intensive care units (ICUs) are managing IC? METHODS: This is a prospective observational multicenter cohort study. During 1 year (2012-2013), 87 French ICUs enrolled consecutive patients with suspected or proven IC (SIC or PIC) and receiving systemic antifungal therapy (SAT). Data were collected up to 28 days after inclusion. RESULTS: We studied 835 patients, 291 with PIC and 544 with SIC. At SAT initiation, patients with SIC were significantly more severe (SAPS II 50.1 ± 18.7 vs. 46.2 ± 18.0). Severe sepsis or septic shock prompted to initiate empiric SAT in 70 % of SIC. Within 4 days in median, the initial SAT was modified in 49 % of patients with PIC vs. 33 % patients with SIC. Modifications were most often motivated by mycological results, and de-escalation was the most frequent change. Regarding compliance to IC management guidelines, echinocandin was used for 182 (62.5 %) patients with PIC, and 287 (52.7 %) of those with SIC; central venous catheter was removed in 87 (54.3 %) of patients with candidaemia, and 43 of the remaining patients received echinocandin; and de-escalation was undertaken after 5 days of SAT in 142 patients, after 10 days in 13 patients. As 20.6 % of SIC were secondarily documented, 403/835 (48 %) patients had finally a proven IC. Candida albicans was the main pathogen (65.3 %), then Candida glabrata (15.9 %). The 28-day mortality rates were 40.0 % in candidaemia, 25.4 % in cIAI, and 26.7 % in deep-seated candidiasis. In the overall population of patients with proven IC, four independent prognostic factors were identified: immunosuppression (Odds Ratio (OR) = 1.977: 1.03-3.794 95 % confidence interval (CI), p = 0.04), age (OR = 1.035; 1.017-1.053 95 % CI; p  extless 0.001), SAPS extgreater46 on ICU admission (OR = 2.894; 1.81-4.626 95 % CI; p  extless 0.001), and surgery just before or during ICU stay (OR = 0.473; 0.29-0.77 95 % CI; p  extless 0.001). CONCLUSION: When SAT is initiated in French ICUs, the IC is ultimately proven for 48 % of patients. Empiric SAT is initiated in severely ill ICU patients. The initial SAT is often adapted, with de-escalation to fluconazole when possible. Mortality rate remains high
ISSN: 2110-5820

hal-01259216
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01259216
DOI : 10.1186/s13613-015-0103-7
PUBMED : 26743881

Éditeur(s) : HAL CCSD
Résumé : Juin 2003
Dans le contexte actuel de mondialisation, de changement climatique et de forte anthropisation de la biosphère, les Petites Antilles s'érigent en monde marginal ou encore en anti-monde. Fracturées du point de vue politique, économique, linguistique et à certains égards culturel, ces territoires insulaires du Bassin caraïbe recèlent de richesses environnementales (physiques, écosystèmiques et paysagères). Comme partout ailleurs dans le monde humanisé, la survie de ces sociétés implique le rétablissement des grands équilibres écologiques consubstantiels à une articulation efficiente entre le naturel, l'urbain et l'agricole. Compte tenu de la pression démographique, variable d'une île à l'autre, la pérennité des écosystèmes en covariance avec un développement économique profitant au plus grand nombre ne peut se concevoir à l'échelle insulaire. Il semble judicieux d'imaginer un développement à l'échelle de l'archipel basé sur la complémentarité, puisque au sein de chaque composante les diverses ressources biologiques terrestres et marines sont insuffisantes pour assurer une autosuffisance en termes de produits de premières nécessités et d'énergie. Le développement des Petites Antilles s'il doit être durable et prendre comme ossature les directives de Rio (Brésil, 1992) et de Johannesburg (Afrique du Sud, 2002), il devra s'inscrire dans une gestion administrative, scientifique, technique et agricole commune dans le cadre d'une Caraïbe fonctionnellement unifiée. A l'unité floristique, faunistique et biocénotique doivent correspondre des stratégies et donc des politiques, similaires mais diversifiées, d'utilisation des ressources abiotiques (énergie éolienne, hydroélectrique et photovoltaïque) et biotiques (écosystèmes terrestres et marins, flore, faune, sols). Malheureusement dans le présent, la compartimentation économique et politique de la Caraïbe rend ces propos profondément utopiques. Néanmoins dans le futur la survie des peuples des Petites Antilles, impliquera un développement durable signifié par des rapports équilibrés entre hommes et milieux.
–––––
In the nowadays context of "globalization", climatic variation and great anthropization of the biosphere, the Lesser Antilles appear as a marginal world. In a political point of view, those islands offer a greatly distinct and fractured image. The same fact can also be observed in an economic, linguistic and, in a certain measure, cultural perspective. Despite of such a statement, those territories of the Caribbean basin keep economic and landscape resources whom survival depends on the re-establishment of the great ecologic structures implying a productive articulation between the natural, the urban and the agricultural. It seems pertinent to imagine a development on the level of the archipelago based upon complementarity since each constituent presents a limited number of earth and marine biologic reserves which do not guarantee an autosubsistance in energy and first nessecity productivity. A lasting development of the Lesser Antilles supposes a necessary and commun administrative, scientific, technical and agricultural management within the setting of a Caribbean functionally unified. Facing the biocenotic unity, a useful strategy, based on a similar and diversified organization in the exploitation of biophisic resources, must be erected. Such statements could be considered as utopic, regarding the situation of politic and economic division in the Caribbean nowadays. However, in the future, the survival of those insular societies will imply a lasting development lying upon an efficient relationship between Man and environment.
https://halshs.archives-ouvertes.fr/halshs-00003054

Droits : info:eu-repo/semantics/OpenAccess
halshs-00003054
https://halshs.archives-ouvertes.fr/halshs-00003054
https://halshs.archives-ouvertes.fr/halshs-00003054/document
https://halshs.archives-ouvertes.fr/halshs-00003054/file/Devpt-durable_JOSEPH-PHILIPPE.pdf

Éditeur(s) : HAL CCSD
Résumé : International audience
Metamorphic soles correspond to m to 500m thick tectonic slices welded beneath most of the large-scale ophiolites.They typically show a steep inverted metamorphic structure where the pressure and temperature conditions ofcrystallization increase upward (from 500100ºC at 0.50.2 GPa to 800100ºC at 1.00.2 GPa), with isogradssubparallel to the contact with the overlying ophiolitic peridotite. The proportion of mafic rocks in metamorphicsoles also increases from the bottom (meta-sediments rich) to the top (approaching the ophiolite peridotites). Thesesoles are interpreted as the result of heat transfer from the incipient mantle wedge toward the nascent slab (associatedwith large-scale fluid transfer and possible shear heating) during the first My of intra-oceanic subduction(as indicated by radiometric ages). Metamorphic soles provide therefore major constraints on early subductiondynamics (i.e. thermal structure, fluid migration and rheology along the nascent slab interface).We present a detailed structural and petrological study of the metamorphic sole from 4 major cross-sections alongthe Oman ophiolite. We show precise pressure–temperature estimates obtained by pseudosection modelling andEBSD measurements performed on both the garnet-bearing and garnet-free high-grade sole. Results allow quantificationof the micro-scale deformation and highlight differences in pressure–temperature–deformation conditionsbetween the 4 different locations, showing that the inverted metamorphic gradient through the sole is not continuousin all locations.Based on these new constraints, we suggest a new tectonic–petrological model for the formation of metamorphicsoles below ophiolites. This model involves the stacking of several homogeneous slivers of oceanic crust leadingto the present-day structure of the sole. In this view, these thrusts are the result of rheological contrasts between thesole and the peridotite as the plate interface progressively cools down. These slivers later underwent several stagesof retrogression (partly mediated by ascending fluids from the slab) from amphibolite- to prehnite/pumpellite-faciesconditions.
Geophysical Research Abstracts
Vienne, Austria

insu-01309369
https://hal-insu.archives-ouvertes.fr/insu-01309369

Éditeur(s) : HAL CCSD
Résumé : International audience
Idiopathic pulmonary fibrosis (IPF) is the most frequent chronic idiopathic interstitial pneumonia in adults. The management of rare diseases in France has been organised by a national plan for rare diseases, which endorsed a network of expert centres for rare diseases throughout France. This article is an overview of the executive summary of the French guidelines for the management of IPF, an initiative that emanated from the French National Reference Centre and the Network of Regional Competence Centres for Rare Lung Diseases. This review aims at providing pulmonologists with a document that: 1) combines the current available evidence; 2) reviews practical modalities of diagnosis and management of IPF; and 3) is adapted to everyday medical practice. The French practical guidelines result from the combined efforts of a coordination committee, a writing committee and a multidisciplinary review panel, following recommendations from the Haute Autorité de Santé. All recommendations included in this article received at least 90% agreement by the reviewing panel. Herein, we summarise the main conclusions and practical recommendations of the French guidelines.
Eur Respir Rev

hal-01063982
https://hal.archives-ouvertes.fr/hal-01063982
DOI : 10.1183/09059180.00001814
PUBMED : 24881074

Éditeur(s) : HAL CCSD
Résumé : International audience
Understanding subduction rheology in both space and time has been a challenge since the advent of plate tectonics.We herein focus on "subduction infancy", which corresponds to the first 0-2 My immediately following subductionnucleation, when a newly born slab penetrates into the overriding plate mantle and heats up.The only remnants of this critical, yet elusive, geodynamic step are thin metamorphic soles, commonly found beneathpristine, 100-1000 km long portions of oceanic lithosphere emplaced on top of continents (i.e. ophiolites).In this study, we show how, during subduction infancy, transient mechanical properties of both the mantle and crustacross the subduction plate interface (during 100s ky) control and hinder the penetration of tectonic plates intothe mantle, and how this results in strong peaks of resistance and even slicing of their surface — leaving behindthin, chopped-off metamorphic slivers (i.e. metamorphic soles).These findings constrain the mechanical behaviour of the subduction plate interface (with implications for couplingprocesses and earthquake generation) as well as the properties of the crust and mantle. They also highlight the roleof fluids in enabling subduction to overcome this early resistance.
Geophysical Research Abstracts
Vienne, Austria

insu-01309386
https://hal-insu.archives-ouvertes.fr/insu-01309386