Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Two genome-wide association studies (GWASs) recently highlighted the HLA-DRA and HLA-DRB5 genes as associated with Parkinson disease (PD). However, because HLA-DRA displays a low level of polymorphisms and HLA-DRB5 is only present in approximately 20% of the population, these findings are difficult to interpret. Our aims were: (1) to replicate and investigate in greater detail the association between PD and the HLA-DR region; (2) to identify PD-associated HLA alleles; and (3) to perform a meta-analysis of our top finding. As part of 2 French population-based case-control studies of PD including highly ethnically homogeneous participants, we investigated the association between PD and 51 Single-nucleotide polymorphisms (SNPs) in the HLA-DR region. HLA-DRB1 alleles were imputed using the HLA(*) IMP software. HLA typing was performed in a subsample of the participants. We performed a meta-analysis of our top finding based on 4 GWAS data sets. Among 499 cases and 1123 controls, after correction for multiple testing, we found an association with rs660895 (OR/minor allele, 0.70; 95% CI, 0.57-0.87) within the HLA-DRB1 gene, which encodes the most polymorphic HLA-DR chain (DRβ). A meta-analysis (7996 cases, 36455 controls) confirmed this association (OR, 0.86; 95% CI, 0.82-0.91; P < .0001). SNP-based imputation of HLA alleles showed an inverse association between PD and the HLA-DRB1(*) 04 allele. We replicated an association between PD and the HLA-DR region and provided further insight into the loci and alleles involved. The highly polymorphic HLA-DRB1 locus contains rs660895, which represents a more legitimate candidate than previous ones. Our finding is in agreement with the hypothesis of an immune component in PD pathophysiology. © 2012 Movement Disorder Society.
ISSN: 0885-3185

inserm-00721562
http://www.hal.inserm.fr/inserm-00721562
http://www.hal.inserm.fr/inserm-00721562/document
http://www.hal.inserm.fr/inserm-00721562/file/Table1.pdf
http://www.hal.inserm.fr/inserm-00721562/file/Table2.pdf

Éditeur(s) : HAL CCSD
Résumé : International audience
The geology of the North Pyrenean Zone in the central Pyrenees allows for the observation in the field of theentire section of the Pyrenean rift, from the mantle to the crust and the Mesozoic cover (pre, syn and post rift).The good knowledge we have of the pre-Alpine history of the Pyrenees allows us to properly constrain the Alpinegeological evolution of the pre-Triassic rocks which record both Variscan and Alpine orogenic cycles.The mantle outcrop as kilometric to centimetric fragments of peridotite dispersed within a carbonate metamorphicbreccia. The study of peridotite serpentinisation shows several events of low-temperature serpentinisation, incontact with seawater. In some locallities, we can observe a mixture of fragments of variously serpentinizedperidotites. This suggests a tectonic context where fragments of peridotites from different structural levels weresampled more or less synchronously.The granulitic basement is characterized by a Variscan syndeformational HT event (300-280 Ma). So farwe have not found any trace of a Cretaceous HT event (> 500C). On the other hand, the basement is affectedby a regional metasomatism that began during the Jurassic and became more spatially focused with time until itwas restricted to the Pyrenean rift during the Aptien, Albian and Cenomanian. The talc-chlorite metasomatism(120-95 Ma) shows an evolution from a static toward a syn-deformation hydrothermal event, under a more or lessnormal geothermal gradient. Extensional deformation is recorded by the reworking of several inherited low-angleVariscan tectonic contacts, but also by dispersed high-angle extensional shear zones formed under greenshistconditions.The metamorphic Mesozoic cover of the basement massifs, which constitute the so-called Internal MetamorphicZone, is an allochtonous unit made of lenses of Mesozoic rocks enclosed into the breccia, whichlocally contains peridotite and basement clasts. The Mesozoic metamorphic carbonates show a first phase ofsyn-metamorphic (450-600C, P < 2 kb) ductile deformation, and subsequent phases of folding and fracturing.The datation of neoformed minerals give a 108-85 Ma time span for the metamorphism. We interpret this brecciaas an abandonment breccia which marks the emergence of the main detachment. The basal contact of the Mesozoiccover has a complex 3D geometry traced by Triassic evaporites. It corresponds to a major pre- and synorogenicpolyphased tectonic contact.All these data show a geometrically complex hyper-extended rift where the crust was not stretched under ahigh geothermal gradient but thinned by the tectonic extraction of relatively thin lenses and perhaps cut by highangle low-grade shear zones. The 3D geometry, as well as the strain records and the breccia lithologies stronglysuggest a non-cylindricity for the exhumation process, probably within a transtentional system
Geophysical Research Abstracts
Vienne, Austria

insu-01510371
https://hal-insu.archives-ouvertes.fr/insu-01510371

Éditeur(s) : Sage Publications
Résumé : It is becoming increasingly clear that humans impact marine ecosystems and their biodiversity to a very considerate degree, and evidence of the scale of impact is growing. An enabling factor for this has been a change in focus from local-level studies to increased emphasis on meta-analysis of global or regional-level analysis of fisheries' impact, Results include the facts that the world's total fish catches have been decreasing over the last decade or more; that larger, predatory fishes (table fish) are becoming increasingly scarcer; and that we are appropriating the ocean shelves' primary productivity to the same level as we are for terrestrial ecosystems. Ecosystems are being eroded in countries throughout the world, and though one might get the impression from the IUCN Red List that it is mainly a developed-country problem, it is alarming that the impact of severe overfishing may be on an even larger scale for developing countries. We describe aspects of the risks overfishing poses to marine ecosystems, and point out how ecosystem approaches to fisheries can be used to evaluate the potential impact of alternative fishing policy scenarios.
Il devient de plus en plus clair que les activités humaines altèrent les écosystèmes marins et leur biodiversité à un degré considérable, et les preures de l'échelle des impacts anthropiques s'accumulent. Un des facteurs déterminants de cette prise de conscience réside dans le changement d'échelle des études de l'impact des pêches qui sont passées d'un niveau local à un niveau global ou régional au travers d'études de type méta-analyse. Les résultats obtenus les plus évocateurs incluent le fait que la totalité des captures mondiales de poissons a diminué pendant la dernière décennie ou plus; que les grands prédateurs (l'essentiel des poissons "de table") deviennent de plus en plus rares; et que nous nous approprions la productivité primaire des plateaux continentaux au même titre que nous nous sommes appropriés celle des écosystèmes terrestres. Les écosystèmes sont érodés dans les pays du monde entier, et bien que la liste rouge de l'IUCN laisse penser que c'est principalement le problème des pays développés, il est alarmant de constater que l'impact de la surpêche excessive pourrait être une échelle bien plus grande encore pour les pays en voie de développement. Nous décrivons certains aspects des risques que pose la surpêche pour les écosystèmes marins, et mettons en exergue comment l'approche écosystémique des pêches peut être employée pour évaluer l'impact potentiel de scénarios alternatifs de règlementation des pêches.
Social Science Information (0539-0184) (Sage Publications), 2007-03 , Vol. 46 , N. 1 , P. 67-86

Droits : 2007 Sage Publications
http://archimer.ifremer.fr/doc/2007/publication-6123.pdf
DOI:10.1177/0539018407073656
http://archimer.ifremer.fr/doc/00000/6123/

Éditeur(s) : Elsevier
Résumé : Herbivorous (20% vegetable protein, 40% carbohydrate) and carnivorous diets (40% marine animal protein, 20% carbohydrate) were experimentally tested to assess their effect on the energy balance and energetic substrates utilized by postlarvae (PL's /15 days) and juvenile shrimp (3-6 g) of Litopenaeus vannamei. Postlarval stage 60 (PL60, early juveniles) shrimps fed HeD and CaD diets, then late juveniles (3-6 g) acclimated to the same diets were tested for their respective energy partitioning potential. No significant differences (p>0.05) on growth were obtained in early juveniles (mean final wet weight of 0.19 g). However in late juvenile stages a significant difference (p<0.05) in growth rate was observed. In terms of energy partitioning, both early and late juveniles seem to spend more energy in respiratory metabolism than in the elimination of excretion products. A change in feed composition based on quality protein sources induced some modifications on shrimp's activity measured by heat increment. Shrimps fed with an herbivorous diet showed a higher heat increment. Interestingly, the early stages of L vannamei display a remarkable capacity to assimilate a plant protein-based and a high carbohydrate level diet. Such capacity with a stimulation of genes would lead to a good adaptation of juveniles receiving all-plant diets to sustain growth performances up to a marketable size. The implications of these findings for the shrimp farming feeding costs are briefly discussed. (C) 2009 Elsevier B.V. All rights reserved.
Aquaculture (0044-8486) (Elsevier), 2009-11 , Vol. 296 , N. 1-2 , P. 123-128

Droits : 2009 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/2009/publication-7402.pdf
DOI:10.1016/j.aquaculture.2009.08.007
http://archimer.ifremer.fr/doc/00000/7402/

Éditeur(s) : HAL CCSD Borntraeger Science Publishers
Résumé : This study characterizes the stratigraphical context as well as the palaeoenvironmental and sealevel trends during the Late Frasnian and Famennian in the Buschteich section (Thuringia, Germany). An integrated approach combines conodont biostratigraphy, chemostratigraphy based on carbon and oxygen isotopes, conodont biofacies analyses and investigations of the morphotypes of foraminifera that occur in the section was applied. Conodonts provided a fine-scale biostratigraphical framework. All the Famennian conodont biozones were identified, with the exception of the three lowest. The Frasnian – Famennian transition was further identified by a positive carbon isotope excursion. This continuous Famennian record is developed in a condensed limestone succession. The reddish Griotte facies, typical of strata of this period, were not documented. Black shales were not developed except for an interval of dark colored mud rocks corresponding to the Hangenberg event at the top of the section. The carbonate succession of Buschteich was deposited in an outer ramp environment, pelagic organisms are the dominant fauna. This is corroborated by the overall dominance of the deep-water conodont genus Palmatolepis. Microfacies, conodont biofacies and foramini fera indicated a deepening trend from the Lower crepida to the Lower rhomboidea Zone, followed by a shallowing trend from the Upper rhomboidea to the praesulcata Zone. This sequence overall matches the sea level reference curve for Euramerica. The timing of maximum water depth at Buschteich, as well as the general sea-level reference record, differs from the Col des Tribes (Montagne Noire, France). Differential uplift or overprinting of the long-term eustatic changes may be the cause of the discrepancy in the local sea-level records.
ISSN: 0078-0421

hal-01623111
https://hal.archives-ouvertes.fr/hal-01623111
DOI : 10.1127/nos/2016/0318

Éditeur(s) : Université de Bretagne Occidentale
Résumé : The objective of the present work is to study the formation of the passive continental margins of the Central Segment of the South Atlantic, most particularly the Congo and Angola margins. We propose a combined approach, which integrates structural constraints based on geological cross-sections (based on seismic data) and global constraints based on plate kinematic reconstructions. The structural study is based on : i) MCS and refraction data collected during the ZaiAngo programme (a joint project conducted by Ifremer and Total) ; ii) proprietary, industrial seismic data (courtesy of Total) from the Angola margin and iii) on all available seismic lines from the Africa and Brazil conjugated margins, between Walvis Ridge and the Equatorial Fracture Zones. Based on theses data, three structural domains (continental, transitional and oceanic) have been defined, the major characteristics of which are : Crustal thinning occurs abruptly, mostly below the continental slope, over a lateral distance of less than 50 km. The top of the crust deepens as the Moho shallows. Only a few extensional structures are observed ; tilted blocks are very few (one or two, depending on the profile), found only on the upper part of the slope and sealed by a discordance prior to salt deposition. The transitional domain is characterized by the existence of a pre-salt basin lying over a thin crustal layer. No tilted blocks are observed in this domain and reflectors within the pre-salt sediment series are parallel to the base of the Aptian salt, over distances greater than 100 km, precluding the possibility of any significant deformation that would imply large horizontal motions. Two types of crust are observed in the transitional domain. "Type I" crust is found below the undeformed pre-salt sediment series located below the eastern part of the basin ; it is characterized by an upper layer of thickness greater than 5 km and a abnormal velocity layer (7.2 - 7.6 km/s), up to 6 km thick. "Type II" crust is less than 5 km thick and found below the salt compressive front that affects the western part of the basin. The salt cover is continuous (no erosion surface is observed), from the continental shelf to the western termination of the basin. Salt was not deposited in a confined environment (like in the Mediterranean), but in a shallow water, lagunal environment. This imposes the zero-level and constrains the paleo-bathymetry at the time of salt deposition, which dates the latest stage of margin formation. Understanding the formation of a margin cannot be approached without studying the homolog margin. Therefore, it is of major importance to reconstruct the closure of the ocean bordered by these homolog margins and take into account the constraints imposed by the kinematic reconstructions on the lateral motions of the lithospheric plates. In order to assess the relative position of the plates at the ocean closure (prior to crustal thinning), a global study was thus performed, integrating all geophysical and geological constraints, in the ocean and on land. The role of african intra-plate deformation and its limits and their consequences have been thoroughly studied. To juxtapose the margins of the central segment of the Southern Atlantic, it is all the margins bordering the Equatorial Atlantic that need to be adjuste precisely. The kinematic study of this last region shows that the reconstruction obtained are reliable, unambiguous with a quantifiable precision The best fitting poles (obtained using the PLACA software), show that it is impossible to close the margins beyond the superposition of the salt fronts, from the Angola and Brazil margins. The geological cross-sections based on seismic data from the homolog margins indicate that a 330 km wide basin with thin (< 12 km) crust was present at the time of the fit. This basin cannot result from horizontal movement related to pure stretching or simple shear, or any model implying conservative volume. This conclusion is consistent with the existence of presalt reflectors parallel to the salt layer wich extends to the platform: the formation of the pre-salt basin must be related to vertical motions. The scenario that we propose for the evolution of the Congo-Angola margin consist in four stages: the first phase corresponds to extensional deformation limited to the few tilted blocks observed on the upper part of the slope. During the second phase, the main crustal thinning occurs, vertical motions prevailes, resulting in the formation of the continental slope and in the subsidence of the basin. The third phase corresponds to the first stress striction: deformation is concentrated in a limited section of the basin, which corresponds to the salt compression front. A proto-oceanic crust is formed, probably composed of thinned continental crust intruded by mantle material. The second stress striction corresponds to the finale phase, resulting in oceanisation senso stricto. The evolution described shows that we can not apply conservative models for margin formation (such as McKenzie and Wernicke or any of their avatars). In order to explain this thinning, one should investigate non-conservative models (implying geochemical transformation, small scale convection, intrusion...) such as those proposed in marginal or continental basins with no horizontal movments.
Ce travail de thèse aborde la formation des marges continentales passives dans le segment central de l'océan Atlantique Sud (plus particulièrement au Congo et en Angola), en intégrant une étude en coupe (étude structurale à partir des coupes sismiques) et une étude en plan (étude cinématique). L'étude structurale de la marge a été réalisée à partir des données de sismique réflexion et réfraction de la campagne Zaïango et d'une compilation de données sismiques réflexion existantes sur toutes les marges africaine et brésilienne entre les zones de fracture équatoriales et la ride de Walvis. L'interprétation de ces données a permis d'individualiser la structure de la marge en trois domaines : continental, transitionnel et océanique et de déterminer quelques points majeurs sur la structuration de la marge. L'amincissement est abrupt, localisé dans la zone de pente continentale et restreint à 50 km. La marge montre peu de structures distensives : seuls un ou deux blocs basculés sont observés en haut de pente continentale. Le domaine transitionnel est caractérisé par la géométrie particulière de la sédimentation anté-salifère, l'absence de blocs basculés et la faible épaisseur de croûte. La couche sédimentaire anté-salifère montre des réflecteurs plans jusqu'à la base du sel, continus sur 100 km, éliminant toutes possibilités de déformation du socle pendant et après son dépôt. La croûte du domaine transitionnel peut-être divisée en deux types : une croûte de type I sur laquelle se déposent les sédiments non déformés, et une croûte de type II sur laquelle se superposent les limites du « front compressif salifère » bien exprimé dans les séries postsalifères. Enfin le sel, que l'on observe depuis la plate-forme jusqu'au bassin profond, ne se dépose pas dans un bassin confiné (comme en Méditerranée) mais à un niveau proche de 0 m (ressemblant probablement à un dépôt de type lagunaire) et donne la paléo-bathymétrie au moment de son dépôt qui marque la fin de la période de formation de la marge. La compréhension de la genèse d'une marge ne peut être approchée sans son homologue. Cette simple constatation, cette évidence, montre toute l'importance que l'on doit apporter à la reconstruction cinématique initiale de l'océan qui borde ces marges homologues et aux contraintes imposées par les reconstructions cinématiques sur les mouvements horizontaux des plaques lithosphériques. Afin d'étudier la position des marges au moment de cette fermeture, c'est-à-dire avant amincissement, une étude globale intégrant l'ensemble des données disponibles, géophysiques et géologiques, océaniques et continentales, a été réalisée. Le rôle de la déformation intraplaque africaine, ses limites et leurs conséquences a, en particulier, été l'objet d'une attention poussée. Pour juxtaposer les marges du segment central, ce sont toutes les marges de l'océan Atlantique Equatorial qui doivent être ajustées précisément. L'étude cinématique réalisée de la région équatoriale montre que l'on obtient une reconstruction fiable et sans ambiguïté, avec une précision que l'on peut quantifier. Les pôles issus de cette étude (et calculés avec le Logiciel PLACA) indiquent qu'il est impossible d'obtenir une fermeture plus serrée que celle qui conduit à la superposition des fronts salifères brésilien et angolais : les coupes issues de la sismique réflexion des deux marges indiquent qu'il subsiste un bassin aminci, large de plus de 330 km et dont la croûte n'excède jamais 13 kilomètres d'épaisseur. La formation de ce bassin ne peut résulter de mouvements horizontaux, ce qui exclut un amincissement par étirement (pure stretching) ou par l'existence d'une faille de détachement (simple shear) ou par quelque modèle conservatif que ce soit. Cette constatation corrobore l'observation de la présence d'horizons anté-salifère parallèles, entre eux et au sel, couche salifère que l'on retrouve sur la plate-forme : la création de ce bassin anté-salifère ne peut être que liée à un mouvement vertical. Le schéma d'évolution que nous proposons à partir des données structurales et des contraintes cinématiques présente quatre étapes : le premier stade correspond à une phase de déformation distensive limitée aux quelques rares blocs basculés observés en haut de pente continentale. C'est durant la deuxième étape que se déroule la phase d'amincissement principal, les mouvements verticaux prévalent, aboutissant à la formation de la pente continentale et à la subsidence du bassin. La troisième phase correspond à une première striction des contraintes : la déformation se concentre sur une partie réduite du bassin, coïncidant avec le front salifère compressif. Une proto-croûte océanique se forme, probablement composée de croûte continentale amincie et intrudée de matériel mantellique. La seconde striction correspond à la phase finale de formation de la marge et aboutit à l'océanisation sensu stricto. L'étude cinématique et la description de l'évolution de la marge à partir des données sismiques montre donc que l'on ne peut envisager l'application d'un modèle de genèse des marges avec conservation de volume (type McKenzie ou Wernicke et leurs avatars) : pour expliquer l'amincissement du bassin, il faudrait probablement nous intéresser aux modèles non-conservatifs (impliquant transformation, convection à petite échelle, ...) qui sont déjà invoqués pour la formation des bassins marginaux ou continentaux, sans mouvements horizontaux.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/2003/these-82.pdf
http://archimer.ifremer.fr/doc/00000/82/

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : 17 pages, 11 figures.
International audience
The problem addressed in this paper is the automatic extraction of names from a document image. Our approach relies on the combination of two complementary analyses. First, the image-based analysis exploits visual clues to select the regions of interest in the document. Second, the textual-based analysis searches for name patterns and low-level word textual features. Both analyses are then combined at the word level through a neural network fusion scheme. Reported results on degraded documents such as facsimile and photocopied technical journals demonstrate the interest of the combined approach.
ISSN: 1433-7541

hal-00329459
https://hal.archives-ouvertes.fr/hal-00329459
DOI : 10.1007/s10044-006-0038-6

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Rapid cold hardening (RCH) is a form of thermal acclimation that allows ectotherms to fine-tune their physiological state to match rapid changes in thermal environment. Despite progress in recent years, there is still a considerable uncertainty regarding the physiological basis of RCH in insects. Here we investigated the physiological response of adult Drosophila melanogaster to a gradual reduction of temperature from 25 to 0°C followed by 1h at 0°C. As expected, this RCH treatment promoted cold tolerance, and so we hypothesized that this change could be detected at the proteomic level. Using 2D-DIGE, we found that only a few proteins significantly changed in abundance, and of these, we identified a set of four proteins of particular interest. These were identified as two different variants of glycogen phosphorylase (GlyP) of which three spots were up-regulated and another was down regulated. In subsequent experiments, we quantified upstream events by measuring the GlyP mRNA amount, but we found no marked effect of RCH. We also examined downstream events by measuring GlyP activity and the level of free sugars. We found no effect of RCH on GlyP activity. On the other hand, screening of whole animal sugar contents revealed a small increase in glucose levels following RCH while trehalose content was unaltered. This study highlights a complex regulation of GlyP in relation to RCH where we found associations between the cold tolerance, the protein abundance and the metabolite concentrations but no changes in mRNA expression and enzyme activity. These data stress the necessity of combining the hypothesis-generating power of an 'Omics' approach with subsequent targeted validations across several levels of the biological organization. We discuss reasons why different biological linked levels do not necessarily change stoichiometrically.
ISSN: 0022-1910

hal-00991032
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00991032
DOI : 10.1016/j.jinsphys.2014.01.009
PUBMED : 24508557

Éditeur(s) : HAL CCSD Springer Verlag/EDP Sciences
Résumé : No efficient method is available to compare multi-locus estimates of diversity while taking into account inter-locus and inter-population stochastic variance. The advent of genome scan approaches makes the development of such tests absolutely necessary. We developed a method to compare genome-wide diversity estimates while taking into account-and factoring out-variation in census size and making use of inter-locus variance to assess significance of differences in diversity levels. An approach based on rarefaction with bootstrap re-sampling (RaBoT) was implemented into a test of multi-locus comparison of diversity coded in R. The properties of the test were studied by applying it to simulated populations with varying diversity levels and varying differences in diversity levels. The test was then applied to empirical data from disturbed and undisturbed populations of Virola michelii (Myristicaceae) genotyped at 693 amplified fragment length polymorphism (AFLP) markers. RaBoT was found to be rather conservative, with large numbers of false negatives when the diversity in the compared populations was similar, and false positives mostly associated to comparisons of populations with extremely high levels of diversity. When applied to empirical data, RaBoT detected higher genetic diversity in a post-disturbance than in an undisturbed population and lower genetic diversity in a seedling than in the corresponding adult population, but it also revealed differences in diversity between subgroups within the disturbed and undisturbed plots. RaBoT is a sensitive method to compare multi-locus levels of diversity that can be applied both at the genotype level for dominant markers (e.g. AFLP) and at the allele level for biallelic codominant markers (e.g. single-nucleotide polymorphisms).
ISSN: 1286-4560

hal-01032413
https://hal.archives-ouvertes.fr/hal-01032413
DOI : 10.1007/s13595-013-0302-z

Éditeur(s) : Elsevier
Résumé : The New Caledonia blue shrimp Litopenaeus stylirostris is commercially produced under semi-intensive rearing conditions. The size of the farming earthen ponds (5–10 ha) and the subsequent production constraints make it difficult to use them as experimental units for random experiments. Moreover, since every pond has its own characteristics, ponds' effects cannot be ruled out, thus making it hard to define true replicates. In order to design future experiments under conditions resembling those used in production, we evaluated the possible use of floating cages as experimental units with the aim of assessing treatment effects with a reasonable statistical power. To this end, two sets of floating cages were placed respectively in two different ponds in a commercial farm. In both cases the zootechnical conditions in the cages were similar in post-larvae origin, management, and diet and feeding regime. The aim of the study was to evaluate on a technical basis the possibility of rearing shrimps in floating cages set up in earthen ponds and to assess this method from a statistical standpoint. Shrimps reared in and outside the cages showed comparable growth and survival rates. The variability in the zootechnical parameters between cages, expressed as the estimated coefficient of variation (CV) for survival rate, total final biomass (g), final body weight (g), daily increment in body weight (g day− 1) and FCR were 11.0, 13.7, 4.4, 5.4, and 7.0%, respectively. On the basis of these figures, we calculated for a given statistical power (80%) the number of replicates (cages) that would be required to reveal significant differences between two treatments, at a 5% level of significance. We found that for expected differences of 20% from the control mean, 3 and 6 floating cages per treatment would be reasonable to determine statistical differences for growth parameters and survival rate, respectively. Moreover, we showed a significant pond effect in regard to survival and growth between the two sets of cages. These results illustrated the within-farm variability among the ponds, and confirmed that the specific characteristics of each pond from the same farm make it difficult to use the ponds themselves as experimental units. The study demonstrates that rearing in floating cages is an economical, powerful and sensitive experimental tool for shrimp culture studies specifically carried out under conditions close to semi-intensive production.
Aquaculture (0044-8486) (Elsevier), 2008-07 , Vol. 279 , N. 1-4 , P. 63-69

Droits : 2008 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/2008/publication-4363.pdf
DOI:10.1016/j.aquaculture.2008.03.053
http://archimer.ifremer.fr/doc/00000/4363/

Éditeur(s) : Elsevier
Résumé : Emplacement of post-glacial turbidites is commonly controlled by rapid changes in sea level or by seismicity. On the continental rise of the Gulf of Lions (Western Mediterranean), an aseismic area, we identified turbiditic beds deposited during the rising stage and highstand of sea level. Swath bathymetry, sediment cores, in situ Cone Penetrating Tests (CPTU), heavy mineral associations and radiocarbon dating determined the source, composition, distribution and age of the turbiditic beds. Turbidites are composed of homogeneous to positively graded silts to medium sand with quartz (up to 90%), shell debris and shelfal benthic faunas. Their distribution on the sea floor is very patchy and controlled by abundant inherited erosional bedforms. Their source is found in relict regressive sands at the outershelf. Their deposition occurred just after the onset of the post-glacial sea level rise and the concomitant sediment starvation of the Rhone deep sea turbiditic system until recently. Whilst canyons are fed with sand by strong seasonal hydro-sedimentary dynamics on the outershelf, the emplacement of post-glacial turbidites is not controlled by sea level changes but probably by the periodic flushing of the canyons. Our study revealed that this low energy aseismic margin undergoes significant transport of sand, down to the base of slope, during the sea-level rise and the Holocene highstand.
Marine Geology (0025-3227) (Elsevier), 2009-02 , Vol. 257 , N. 1-4 , P. 65-86

Droits : 2009 Published by Elsevier Ltd.
http://archimer.ifremer.fr/doc/2009/publication-6316.pdf
DOI:10.1016/j.margeo.2008.10.013
http://archimer.ifremer.fr/doc/00000/6316/

Éditeur(s) : HAL CCSD
Résumé : 6 pages
In a Spiking Neural Networks (SNN), spike emissions are sparsely and irregularly distributed both in time and in the network architecture. Since a current feature of SNNs is a low average activity, efficient implementations of SNNs are usually based on an Event-Driven Simulation (EDS). On the other hand, simulations of large scale neural networks can take advantage of distributing the neurons on a set of processors (either workstation cluster or parallel computer). This article presents DAMNED, a large scale SNN simulation framework able to gather the benefits of EDS and parallel computing. Two levels of parallelism are combined: Distributed mapping of the neural topology, at the network level, and local multithreaded allocation of resources for simultaneous processing of events, at the neuron level. Based on the causality of events, a distributed solution is proposed for solving the complex problem of scheduling without synchronization barrier.
https://hal.archives-ouvertes.fr/hal-00015137

hal-00015137
https://hal.archives-ouvertes.fr/hal-00015137
https://hal.archives-ouvertes.fr/hal-00015137v2/document
https://hal.archives-ouvertes.fr/hal-00015137/file/hal_damned.pdf
ARXIV : cs.NE/0512018

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Le changement climatique et le développement durable du tourisme représentent des enjeux majeurs pour l’avenir du tourisme dans plusieurs régions du monde, notamment aux Antilles françaises. Aussi, la présente étude se propose d’analyser et d’évaluer les effets économiques de la variation climatique sur le secteur touristique à la Guadeloupe et à la Martinique, pour quatre raisons essentielles : (a) le secteur du tourisme et les petites économies insulaires qui en dépendent, comme celles de la Guadeloupe et de la Martinique, sont fortement sensibles à la variabilité et au changement du climat. (b) la vulnérabilité intrinsèque de ces petites destinations et de leurs infrastructures à l’élévation du niveau de la mer et aux évènements climatiques extrêmes (cyclones, inondations, sécheresse), (c) la haute dépendance de l’industrie touristique régionale à l’utilisation des énergies fossiles, (d) enfin, en raison du fait qu’aucune évaluation économique chiffrée n’a été produite à ce jour sur les effets économiques de la la variation climatique sur le secteur touristique à la Guadeloupe et à la Martinique. Par conséquent, il importe de cerner dans ces deux régions les conséquences possibles de ce changement au plan touristique et d’envisager le cas échéant des stratégies d’adaptation et d’atténuation. Ce faisant, cette étude se fixe quatre objectifs principaux : (a) examiner les facteurs qui influencent la demande et l’offre de tourisme aux Antilles Françaises ; (b) effectuer à l’aide d’un modèle de demande touristique, l’impact économique de ces facteurs sur le nombre d’arrivées ainsi que sur la dépense touristique dans ces régions ; (c) évaluer et projeter en termes de coût, les effets du changement climatique sur l’activité touristique ; et (d) proposer aux autorités locales, des stratégies d’adaptation et d’atténuation face au défi du changement climatique.L’évaluation de ces différents effets est abordée ici à l’aide d’un modèle structurel de base (MSB) et d’un modèle structurel général (MSG), inspirés tous deux des travaux de Harvey (1990) pour capter à l’aide d’un indice climato-touristique, les éléments du climat qui impactent l’activité touristique. Cet indice synthétique est calculé en se basant sur les données climatiques du passé selon deux scénarios climatiques proposés par le groupe d’experts intergouvernemental sur l’évolution du climat (GIEC) – un scénario pessimiste A2, et un scénario optimiste B2-. Les résultats issus de l’application de ces modèles montrent que les caractéristiques climato-touristiques de la Guadeloupe et de la Martinique subiront vraisemblablement un déclin à long terme, et devraient au plan économique impacter négativement le secteur touristique de ces destinations, se traduisant par des pertes à la fois d’attractivité et de chiffre d’affaires du secteur. Les pertes subies par le tourisme en raison du changement climatique s’élèveraient à l’horizon 2100, et selon le scénario A2, à 45 millions d’euros à la Guadeloupe soit 0,7% de son PIB 2004, et à 60 millions d’euros à la Martinique soit 0,8% de son PIB 2004.
Climate change and the tourism sustainable development are important challenges for tourism future trends of many countries, including the French West Indies. Therefore, this study provides an evaluation of the likely economic effects of climate change on tourism sector in Guadeloupe and Martinique, and identifies four reasons why these countries should be concerned about the potential effects of climate change on tourism: (a) Guadeloupe and Martinique are island destinations very sensitive to climate change; (b) their intrinsic vulnerability and their infrastructure to sea level rise and extreme climatic events (e.g. hurricanes and floods); (c) the high dependence of their tourist industry on carbon-based fuels; and (d) up to date, no economic evaluation of climate change on tourism sector in Guadeloupe and Martinique is provided. Therefore, this study attempted to quantify the likely effects of the changes in the climatic factors on the economy of the French West Indies. There are four main objectives in this study. The first is to examine the factors that influence the demand and supply tourism in Guadeloupe and Martinique. The second is to forecast the impact of climate change to tourism arrivals until 2050 under two scenarios from the intergovernmental panel on climate change (IPCC) – A2: pessimistic scenario and B2: optimistic scenario-. Third is to evaluate and forecast the cost of climate change to the tourism sector until 2100. The fourth is to recommend to authorities the adaptation and mitigation strategies that can be undertaken by the tourism sector to French West Indies to address climate change.Following Harvey (1990), a Basic Structural Model (BSM) and a General structural Model (GSM), are employed to model tourist arrivals to Martinique. A tourism climatic index (TCI) conceptualized by Mieczkowski (1985) is used in this model to capture the elements of climate that impact on a destination’s experience. The results suggest that under both scenarios, the island’s key tourism climatic features will probably decline, and therefore, negatively impact on the destination experience of visitors. Tourism losses due to climate change are projected in 2100 to 45 millions euros in Guadeloupe, or 0.7% of its GDP, and to 60 millions euros in Martinique, or 0,8% of its GDP.
Guadeloupe
Martinique

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.6750
http://journals.openedition.org/etudescaribeennes/6750

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
During compressive events, deformation in sedimentary basins is mainly accommodated by thrust faulting and related fold growth. Thrust faults are generally rooted in the basement and may act as conduits or barriers for crustal fluid flow. Most of recent studies suggest that fluid flow through such discontinuities is not apparent and depends on the structural levels of the thrust within the fold-and-thrust belt. In order to constrain the paleofluid flow through the Jaca thrust-sheet-top basin (Paleogene southwest-Pyrenean fold-and-thrust belt) this study compares on different thrust faults located at different structural levels. The microstructures in the different fault zones studied are similar and consist of pervasive cleavage, calcite shear veins (SV1), extension veins (EV1) and late dilatation veins (EV3). In order to constrain the nature and the source of fluids involved in fluid-rock interactions within fault zones, a geochemical approach, based on oxygen and carbon stable isotope and trace element compositions of calcite from different vein generations and host rocks was adopted. The results suggest a high complexity in the paleohydrological behaviors of thrust faults providing evidence for a fluid-flow compartmentalization within the basin. Previous studies in the southern part of the Axial Zone (North of the Jaca basin) indicates a circulation of deep metamorphic water, probably derived from the Paleozoic basement, along fault zones related to the major basement Gavarnie thrust. In contrast, in northern part of the Jaca basin, the Monte Perdido thrust fault is affected by a closed hydrological fluid system involving formation water during its activity. The Jaca and Cotiella thrust faults, in turn, both located more to the south in the basin, are characterized by a composite fluid flow system. Indeed, stable isotope and trace element compositions of the first generations of calcite veins suggest a relatively closed paleohydrological system, whereas the late calcite vein generations, which are probably associated with the late tectonic activity of the basin, support a contribution of both meteoric and marine waters. Based on these results, a schematic fluid-flow model is presented. This model allows visualization of three main fluid flow compartments along a N-S transect.
ISSN: 0264-8172

hal-00963606
https://hal.archives-ouvertes.fr/hal-00963606
DOI : 10.1016/j.marpetgeo.2013.09.005

Éditeur(s) : HAL CCSD
Résumé : International audience
Background Chlordecone is a persistent organochlorine insecticide with well-defined estrogenic properties. It was intensively used in the French West Indies until 1993 to control the banana root borer. Because of the long-term contamination of soils and water, the population is currently exposed to chlordecone through food consumption. Chlordecone has been found in the blood of pregnant women and in cord blood. It has been shown to be an endocrine-disrupting chemical and exposure during pregnancy may affect fetal growth. Objectives The objective of our study was to examine the association between prenatal exposure to chlordecone and fetal growth based on the TIMOUN birth cohort conducted in Guadeloupe, with a focus on the potential modification of this relationship by maternal body mass index (BMI) and gestational weight gain (GWG). Methods Chlordecone was determined in cord plasma at birth in 593 babies. Birth weight was the indicator of fetal growth. Maternal pre-pregnancy BMI and GWG were determined. Adherence to GWG recommendations of the US Institute of Medicine based on maternal pre-pregnancy BMI was assessed. Birth weight was analyzed relative to cord blood chlordecone levels using linear and non-linear regression models. Results Overall chlordecone in cord blood was not associated with birth weight, but we found an interaction between chlordecone exposure with GWG and adherence to GWG recommendations. After stratification by GWG, we found a significant U-shaped association between birth weight and chlordecone exposure, within the upper quartiles of GWG or excessive GWG. Conclusion Chlordecone exposure may affect fetal growth, particularly when excessive GWG is present. © 2016 Elsevier Inc.
Environmental Research

hal-01367154
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01367154
DOI : 10.1016/j.envres.2016.08.004
PUBMED : 27560981

Éditeur(s) : HAL CCSD Cambridge University Press (CUP)
Résumé : We present detailed biostratigraphy based on conodonts and palaeoenvironmental trends deduced from microfacies and conodont abundance through the Famennian (Late Devonian) at Col des Tribes (Montagne Noire, France). The succession is characterized by micritic limestones deposited in settings oscillating between mid to outer ramp. Facies contain poor fauna, widely dominated by nektonic organisms. This section is complete and one of the most conodont-rich for the Famennian of the north Gondwana-related area. The Upper Kellwasser event (Frasnian–Famennian boundary) and the Hangenberg (Devonian–Carboniferous boundary) have been lithologically identified. They are characterized by decimetre-thick black dysoxic to anoxic argillaceous sediments. The Condroz and annulata events, although not materialized by lithological changes, have been positioned due to the precise stratigraphy. The first event occurred during the deposition of condensed ferruginous facies (griotte limestones) and the second event during the deposition of micrites barren of benthic fauna. The combination of information from both facies and conodont biofacies changes allows a general sea-level curve through the entire Famennian for north Gondwana to be proposed for the first time. At Col des Tribes, the general trend is a slight deepening upwards from triangularis to trachytera zones, then a pronounced shallowing-upwards trend from upper trachytera to praesulcata zones. This curve correlates with the well-known reference curve from Euramerica concerning the late Famennian (trachytera to praesulcata Zones). There are some discrepancies in minor cycles which can be explained by tectonical phenomena at the onset of the edification of the Variscan belt in Europe.
ISSN: 0016-7568

hal-01115222
https://hal.archives-ouvertes.fr/hal-01115222
DOI : 10.1017/S0016756813000927

Éditeur(s) : Elsevier
Résumé : The family Kareniaceae is mostly known in France for recurrent blooms of Karenia mikimotoi in the Atlantic, English Channel, and Mediterranean Sea and for the unusual green discoloration in the saltwater lagoon of Diana (Corsica) caused by Karlodinium corsicum in April 1994. In terms of diversity, this taxonomic group was long overlooked owing to the difficult identification of these small unarmored dinoflagellates. In this study, thanks to the molecular characterization performed on single cells from field samples and cultures, twelve taxonomic units were assigned to the known genera Karenia, Karlodinium and Takayama, whereas one could not be affiliated to any described genus. The molecular phylogeny inferred from the D1–D2 region of the LSU rDNA showed that five of them formed a sister taxon of a known species, and could not be identified at species-level, on the basis of molecular analysis only. Among these latter taxa, one Karlodinium which was successfully cultured was investigated by studying the external morphological features (using two procedures for cells fixation), ultrastructure, pigment composition, and haemolytic activity. The results of our analyses corroborate the genetic results in favour of the erection of Karlodinium gentienii sp. nov., which possesses an internal complex system of trichocysts connected to external micro-processes particularly abundant in the epicone, and a peculiar pigment composition. In addition, preliminary assays showed a haemolytic activity.
Harmful Algae (1568-9883) (Elsevier), 2014-12 , Vol. 40 , P. 75-91

Droits : 2014 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/00225/33611/32310.pdf
DOI:10.1016/j.hal.2014.10.006
http://archimer.ifremer.fr/doc/00225/33611/

Éditeur(s) : HAL CCSD
Résumé : Iran covers a large area limited in longitude by the meridians 44°E and 64°E and in latitude by the parallels 25°N and 40°N. Mapping a new gravity field over Iran is the first important data for geodetic, geophysicaland geodynamical considerations. In this thesis, the gravity measurements are used to determine the gravimetric geoid over Iran. This geoid is coupled with the GPS height and altitude (levelling) to realize an operational vertical surface at the territory of Iran. The contribution of the principal geodetic and gravimetric works realized in recent years are the establishment of: 1) the national absolute gravity network of Iran (NAGNI09), 2) the national gravity calibration line of Iran (NGCLI10) and 3) the multi-observations geodetic and gravimetric network of Iran (MPGGNI10). The absolute gravity network consists in 24 stations where the gravity measurement has been realized with the help of gravimeters FG5, with a precision better than 5μ Gal. The repetition of the observations at two stations between 2000 and 2007 makes obvious the inter-annual variations of gravity in relation of the amount of underground water changes and (or) tectonic deformation. The absolute gravity network has served the base stations for the realization of the MPGGNI10 geodetic and gravimetric network with a mesh of 55 km, at which the gravity is measured with the help of relative gravimeters CG-5 and CG-3/M, the GPS height and the altitude with a precision of 0.010 mGal, 0.03 m, and 3mm km respectively. The remove-restore technique coupled with the Helmert's condensation method is chousen to compute a new gravimetric geoid model, IRGeoid10, with a absolute and relative precision of the order of 0.26 m and 2.8 ppm respectively. The gravimetric geoid is adjusted at the GPS/levelling points to define new vertical reference surface over Iran
L'Iran couvre une grande superficie en longitude entre les méridiens 44°E et 64°E et en latitude entre les parallèles 25°N et 40°N. la cartographie de champ de pesanteur sur l'Iran est de premiére importance pour des considérations d'ordre géodésique, géophysique et geodynamique. Dans cette thèse, les mesures de pesanteur sont utilisées pour déterminer le géoïde gravimétrique sur l'Iran. Ce géoïde est couplé à la mesure de hauteur GPS et d'altitude (nivellement) pour réaliser une surface verticale opérationnelle sur le territoire Iranien. La contribution aux principaux travaux géodésiques et gravimétriques réalisés ces dernières années porte sur l'établissement: 1) du réseau national de gravimétrique absolu de l'Iran (NAGNI09), 2) de la ligne nationale d'étalonnage de gravimétrique de l'Iran (NGCLI10), 3) du réseau multi- observations géodésiques et gravimétriques de l'Iran (MPGGNI10). Le réseau gravimétrique absolu, comporte 24 stations où la mesure de la pesanteur a été réalisée à l'aide de gravimètres FG5, avec une précision meilleure que 5μ Gal. La répétition des observations sur deux sites entre 2000 et 2007 met en évidence des variations inter-annuelles de la pesanteur en relation avec l'évolution du contenu en eau du sous-sol et (ou) la déformation tectonique. Le réseau a servi de point d'appui pour la réalisation du réseau géodésique et gravimétrique MPGGNI10 de maille 55 km sur lequel a été mesuré la pesanteur à l'aide des gravimètres relatifs CG5 et CG-3/M, la hauteur de GPS et l'altitude avec une précision respectivement de 0.010 mGal, 0.03 m et 3mm km . La technique de retrait- restoration couplée à la méthode de condensation de Helmert a permis de calculer un nouveau modèle de géoïde gravimétrique, IRGeoid10, avec une précision absolue et relatif respectivement de l'ordre de 0.26m et 2.8 ppm. Ce géoïde est ajusté aux points GPS nivelés pour définir un nouveau référentiel des altitudes sur l'Iran.
https://tel.archives-ouvertes.fr/tel-00627614

tel-00627614
https://tel.archives-ouvertes.fr/tel-00627614
https://tel.archives-ouvertes.fr/tel-00627614/document
https://tel.archives-ouvertes.fr/tel-00627614/file/TheseYaghoubHatamDef.pdf

Éditeur(s) : HAL CCSD American Geophysical Union (AGU)
Résumé : International audience
This paper presents a new balanced structural cross-section of the Jaca thrust-sheet-top basin of the southern Pyrenees combined with paleo-thermometry and apatite fission track (AFT) thermochronology data. The cross-section, based on field data and interpretation of industrial seismic reflection profiles, allows refinement of previous interpretations of the south-directed thrust system, involving the identification of new thrust faults, and of the kinematic relationships between basement and cover thrusts from the middle Eocene to the early Miocene. AFT analysis shows a southward decrease in the level of fission track resetting, from totally reset Paleozoic rocks and lower Eocene turbidites (indicative of heating to Tmax > ~120 °C), to partially reset middle Eocene turbidites and no/very weak resetting in the upper Eocene-lower Oligocene molasse (Tmax < ~60 °C). AFT results indicate a late Oligocene-early Miocene cooling event throughout the Axial Zone and Jaca Basin. Paleo-maximum temperatures determined by vitrinite reflectance measurements and Raman spectroscopy of carbonaceous material reach up to ~240 °C at the base of the turbidite succession. Inverse modelling of AFT and vitrinite reflectance data with the QTQt software for key samples show compatibility between vitrinite-derived Tmax and the AFT reset level for most of the samples. However, they also suggest that the highest temperatures determined in the lowermost turbidites correspond to a thermal anomaly rather than burial heating, possibly due to fluid circulation during thrust activity. From these results, we propose a new sequential restoration of the south Pyrenean thrust system propagation and related basin evolution.
ISSN: 0278-7407

insu-01312746
https://hal-insu.archives-ouvertes.fr/insu-01312746
https://hal-insu.archives-ouvertes.fr/insu-01312746/document
https://hal-insu.archives-ouvertes.fr/insu-01312746/file/Labaume_et_al-2016-Tectonics.pdf
DOI : 10.1002/2016TC004192

Éditeur(s) : HAL CCSD
Résumé : International audience
Kisspeptins are well known as mediators of the coordinated communication between the brain-pituitary axis and the gonads in many vertebrates. To test the hypothesis that gonadal steroids regulate kiss1 and kiss2 mRNA expression in European sea bass (a teleost fish), we examined the brains of gonad-intact (control) and castrated animals, as well as castrated males (GDX) and ovariectomized females (OVX) that received testosterone (T) and estradiol (E2) replacement, respectively, during recrudescence. In GDX males, low expression of kiss1 mRNA is observed by in situ hybridization in the caudal hypothalamus (CH) and the mediobasal hypothalamus (MBH), although hypothalamic changes in kiss1 mRNA levels were not statistically different among the groups, as revealed by real-Time PCR. However, T strongly decreased kiss2 expression levels in the hypothalamus, which was documented in the MBH and the nucleus of the lateral recess (NRLd) in GDX T-Treated sea bass males. Conversely, it appears that E2 evokes lowkiss1mRNAin the CH, while there were cells expressing kiss2 in the MBH and NRLd in these OVX females. These results demonstrate that kisspeptin neurons are presumably sensitive to the feedback actions of sex steroids in the sea bass, suggesting that the MBH represents a major site for sex steroid actions on kisspeptins in this species. Also, recent data provide evidence that both positive and negative actions occur in key factors involved in sea bass reproductive function, including changes in the expression of gnrh-1/gonadotropin, cyp19b, er and ar genes and sex steroid and gonadotropin plasma levels in this teleost fish. © 2016. Published by The Company of Biologists Ltd.
Journal of Experimental Biology

hal-01406072
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01406072
DOI : 10.1242/jeb.137364
PUBMED : 27591305