Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The use of recombinant antigens has been shown to improve both the sensitivity and the standardization of the serological diagnosis of Farmer's lung disease (FLD). The aim of this study was to complete the panel of recombinant antigens available for FLD serodiagnosis with antigens of Lichtheimia corymbifera, known to be involved in FLD. L. corymbifera proteins were thus separated by 2D electrophoresis and subjected to western blotting with sera from 7 patients with FLD and 9 healthy exposed controls (HEC). FLD-associated immunoreactive proteins were identified by mass spectrometry based on a protein database specifically created for this study and subsequently produced as recombinant antigens. The ability of recombinant antigens to discriminate patients with FLD from controls was assessed by ELISA performed with sera from FLD patients (n = 41) and controls (n = 43) recruited from five university hospital pneumology departments of France and Switzerland. Forty-one FLD-associated immunoreactive proteins from L. corymbifera were identified. Six of them were produced as recombinant antigens. With a sensitivity and specificity of 81.4 and 77.3% respectively, dihydrolipoyl dehydrogenase was the most effective antigen for discriminating FLD patients from HEC. ELISA performed with the putative proteasome subunit alpha type as an antigen was especially specific (88.6%) and could thus be used for FLD confirmation. The production of recombinant antigens from L. corymbifera represents an additional step towards the development of a standardized ELISA kit for FLD diagnosis. © 2016 Rognon et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ISSN: 1932-6203

hal-01367148
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01367148
DOI : 10.1371/journal.pone.0160888

Résumé : La connaissance des facteurs qui influent sur les populations de tiques et en particulier sur leurs distributions est un préalable indispensable à l’étude des maladies qu’elles transmettent. Parmi eux, l’importance des facteurs biotiques et en particulier celle de la compétition interspécifique est peu connue et souvent négligée. L’objectif de ce travail était d’évaluer le rôle de la compétition interspécifique sur la distribution de deux espèces de tiques d’importance vétérinaire, Amblyomma variegatum et A. hebraeum. Alors que seule A. variegatum favorise la transmission de la dermatophilose, une maladie de peau débilitante pour les ruminants, les deux espèces sont vectrices de la cowdriose, maladie due à une bactérie Ehrlichia ruminantium qui représente une contrainte économique majeure pour l’élevage. L’impact de l’espèce vectrice dans l’épidémiologie de la cowdriose (différences de souches circulantes, sévérité des cas,…) est inconnu bien qu’ayant potentiellement des conséquences en termes de surveillance (risque épidémiologique à l’introduction d’animaux) et de contrôle (développement de vaccin régional adapté aux souches circulantes) de la maladie. Ces deux espèces ont une distribution contiguë en Afrique australe avec peu de chevauchement (distribution parapatrique) suggérant une préférence environnementale différentielle ou une compétition exclusive entre elles. Une revue des données de la littérature a permis de mettre en évidence un chevauchement de leur niche trophique, climatique, et temporelle, et une interférence comportementale via la production de leurs phéromones. Les deux espèces pourraient donc rentrer en compétition directement par interférence communicative ou reproductive (hybridation stérile), ou indirectement via le partage de ressources, prédateurs ou pathogènes communs. Le rôle des facteurs biotiques et abiotiques sur le maintien de la parapatrie de ces deux espèces a été analysée (i) d’une part par la comparaison de leur niche environnementale réalisée en Afrique australe, et aux deux zones de contact au Zimbabwe et Mozambique, par des méthodes d’ordination et de modèles de niche (Maxent) ; (ii) et d’autre part par l’étude de leurs distributions et de leurs interactions (distribution sur les hôtes, croisements hétérospécifiques) dans la zone de contact au Mozambique. Globalement les résultats montrent qu’en Afrique Sud-Est et au Zimbabwe les deux espèces occupent des niches environnementales distinctes, celle d’A. hebraeum incluant des zones plus chaudes et plus sèches que celle d’A. variegatum. Au contraire au Mozambique les deux niches se chevauchent considérablement. L’enquête de terrain dans cette zone montre que les deux espèces y sont moins souvent trouvées en sympatrie que les données prédites, suggérant une distribution en partie déterminée par des interactions biotiques. Dans les rares sites avec présence des deux espèces, A. variegatum et A. hebraeum partagent les mêmes sites de fixation sur les animaux et forment un pourcentage relativement élevé de couples hétérospécifiques. Ce pourcentage, bien que similaire entre les femelles A. variegatum et A. hebraeum, semble impliquer des processus de discrimination spécifique propres aux deux espèces intervenant au niveau de l’agrégation, de la fixation et du contact des individus. Nos résultats suggèrent l’existence d’une compétition exclusive entre les deux espèces, due à une compétition sexuelle probablement associée à une compétition indirecte. La frontière parapatrique semble occuper une position stable le long d’un gradient environnemental au Zimbabwe mais pas au Mozambique. Les conditions entrainant la coexistence ou l’exclusion des deux espèces avec formation d’une frontière parapatrique sont discutés à l’aide de modèles théoriques de compétition.
Studying the factors that influence tick populations and their distributions is an essential pre-requisite to understanding the dynamics of the diseases they transmit. The relative importance of biotic factors such as interspecific competition is not well known and often neglected. The objective of this study was to assess the influence of interspecific competition on the distribution of two tick species of veterinary importance, Amblyomma variegatum and A. hebraeum. Whereas only A. variegatum is known to favor dermatophilosis, a debilitating skin disease of ruminants, both species are good vectors of Ehrlichia ruminantium, the bacteria causing heartwater, a fatal disease of ruminants that presents a major constraint for livestock development in Africa. The impact of vector species in heartwater epidemiology (differences of circulating strains, severity of clinical cases…) is poorly known but may have important implications for surveillance (epidemiological risk of imported animals) and control (adapting regional vaccine programs to circulating strains) of the disease. These two ticks have abutting and marginally overlapping (i.e. parapatric) distributions in southern Africa, suggesting either differential environmental preferences or exclusive competition between the two species. A review of published data highlighted an important overlap of their trophic, climatic and seasonal niche, and existence of chemical behavior interference through pheromone production. Therefore, the two species might compete either directly by communicative or reproductive interference (sterile hybridization), or indirectly by sharing the same resources, predators or pathogens. The role of biotic and abiotic factors in determining parapatry of these species was assessed by (i) comparing their realized environmental niche in southern Africa, and at contact zones in Zimbabwe and Mozambique, using ordination techniques and environmental niche modeling (Maxent); (ii) studying their distributions and their interactions (distribution on co-infested host, heterospecific mating) at the contact zone in Mozambique. Globally, the results indicated the two species occupied distinctly different environmental niches in southern Africa and at the contact zone in Zimbabwe, with the niche of A. hebraeum including both hotter and drier areas than that of A. variegatum. However, in Mozambique their niches overlapped considerably. Field studies within this zone showed that sympatry was observed less frequently than predicted by niche models, suggesting an importance of biotic interactions. At the rare sites where both species were present, A. variegatum and A. hebraeum were observed to share the same preference sites on hosts and formed a high percentage of heterospecific pairs. Though this cross-mating rate was not significantly different between A. variegatum and A. hebraeum females, our observations suggest different mechanism of species discrimination involved for the two species acting at the aggregation, fixation and partner contact level. Our results strongly suggest exclusive competition between these species may arise from sexual competition probably interacting with other indirect forms of competition. The parapatric boundary apparently occupies a stable location along an environmental gradient at the contact zone in Zimbabwe but not in Mozambique. Conditions inducing coexistence or exclusion of both species with the formation of parapatric distributions are discussed in relation to theoretical models of competition. When sexual competition is introduced in these models, the relative frequency of two species is determined by their endogenous fitness (a function of environmental conditions), density dependent effects of competitive interactions, historical distributions and dispersal rates: survival of the first prevails when the immigration rate of a fitter invading species remains lower than an invasion threshold.

http://www.theses.fr/2014AGUY0705/document

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: Heterogeneous patterns of malaria transmission are thought to be driven by factors including host genetics, distance to mosquito breeding sites, housing construction, and socio-behavioural characteristics. Evaluation of local transmission epidemiology to characterize malaria risk is essential for planning malaria control and elimination programmes. The use of geographical information systems (GIS) techniques has been a major asset to this approach. To assess time and space distribution of malaria disease in Bandiagara, Mali, within a transmission season, data were used from an ongoing malaria incidence study that enrolled 300 participants aged under six years old ". Methods: Children's households were georeferenced using a handheld global position system. Clinical malaria was defined as a positive blood slide for Plasmodium falciparum asexual stages associated with at least one of the following signs: headache, body aches, fever, chills and weakness. Daily rainfall was measured at the local weather station. Landscape features of Bandiagara were obtained from satellite images and field survey. QGIS™ software was used to map malaria cases, affected and non-affected children, and the number of malaria episodes per child in each block of Bandiagara. Clusters of high or low risk were identified under SaTScan W software according to a Bernoulli model. Results: From June 2009 to May 2010, 296 clinical malaria cases were recorded. Though clearly temporally related to the rains, Plasmodium falciparum occurrence persisted late in the dry season. Two " hot spots " of malaria transmission also found, notably along the Yamé River, characterized by higher than expected numbers of malaria cases, and high numbers of clinical episodes per child. Conversely, the northeastern sector of the town had fewer cases despite its proximity to a large body of standing water which was mosquito habitat. Conclusion: These results confirm the existence of a marked spatial heterogeneity of malaria transmission in Bandiagara, providing support for implementation of targeted interventions. Background Malaria is one of the leading causes of morbidity and mortality in the world, with an estimated 3.3 billion people at risk of malaria [1]. The incidence of malaria worldwide is estimated to be 216 million cases per year, with 81% of these cases occurring in sub-Saharan Africa. Malaria kills approximately 655,000 people per year; 91% of deaths occur in sub-Saharan Africa [1], mostly in children under five years of age. In Mali, West Africa, malaria represents 36.5% of consultation motives in health center, it is a leading cause of morbidity and mortality children of less than five years of age and the first reason of anaemia in pregnant women [2]. Malaria transmission is seasonal. Malaria parasite transmission and clinical disease are characterized by important microgeographic variation, often between adjacent villages, households or families [3-8]. This local heterogeneity is driven by a variety of factors including human genetics [9,10], distance to potential breeding sites [11,12], housing construction
ISSN: 1475-2875

hal-01307672
https://hal-amu.archives-ouvertes.fr/hal-01307672
https://hal-amu.archives-ouvertes.fr/hal-01307672/document
https://hal-amu.archives-ouvertes.fr/hal-01307672/file/1475-2875-12-82.pdf
DOI : 10.1186/1476-072X-2-5

Résumé : La banane plantain (Musa paradisiaca) est l’aliment de base de millions de personnes dans le monde et sa culture génère des revenus permanents pour un grand nombre d’agriculteurs, dans des plantations de taille petite ou moyenne. Comme dans d’autres régions tropicales, la culture du plantain en Guadeloupe et en Haïti est soumise à de fortes contraintes parasitaires aussi bien telluriques (i.e. du sol : nématodes phytoparasites et charançon du bananier) qu’aériennes (Cercosporiose noire notamment). Les moyens de lutte conventionnels reposent sur l’usage de produits de synthèse dont les effets néfastes sur l’environnement (sols, eaux, animaux) comme sur la santé humaine ne sont plus supportables. Il est donc urgent de réfléchir à des solutions agro-écologiques permettant de rétablir les équilibres biologiques, de maintenir une bonne qualité des sols et une production optimale dans les systèmes de culture plantains. C’est le but de ce travail de thèse qui couple la réalisation d’un diagnostic agro-écologique dans des parcelles paysannes, et le test d’alternatives agro-écologiques en milieu semi-contrôlé. Pour ce faire, une typologie des systèmes de culture plantains a été réalisée à l’issue d’une enquête agro-environnementale dans les deux zones d’étude. Elle a permis de sélectionner 23 parcelles en Guadeloupe et 12 en Haïti dans lesquelles un diagnostic agro-écologique a été conduit. Sur la base de ce diagnostic et de la recherche d’alternatives agro-écologiques à l’usage des produits chimiques, une expérimentation au champ a été mise en place en Guadeloupe en station de recherche, permettant le test de trois pratiques culturales innovantes pour le plantain (seules et combinées), à savoir : i) l’introduction d’une plante de service Paspalum notatum pour la gestion des adventices et la réduction de l’utilisation d’herbicides ; ii) l’apport de vermicompost pour le contrôle des nématodes phytoparasites inféodés au bananier plantain et la fertilisation de celui-ci ; iii) l’utilisation de plants sains PIF (Plants Issus de Fragments de tiges) indemnes de nématodes et de larves de charançon du bananier. La typologie des systèmes de culture plantains révèle que : i) en Guadeloupe les précédents : jachère, ananas et banane plantain sont prédominants avec un niveau d’intensification faible (apports d’intrants chimiques faibles et peu fréquents) ou élevé (apports d’intrants chimiques élevés et plus fréquents) ; ii) en Haïti, les précédents : jachère, banane plantain et manioc prédominent avec un niveau d’intensification faible ou nul (apport d’intrants inexistant). Les résultats du diagnostic agro-écologique montrent que, i) lorsque le niveau d’intensification est faible, les bananeraies plantains pérennes et le précédent-ananas permettent de maintenir une bonne qualité du sol et une bonne régulation des parasites telluriques ; ii) lorsque le niveau d’intensification est fort, les populations d’ingénieurs du sol diminuent drastiquement, alors que le cortège parasitaire tellurique augmente sans que cela n’affecte l’obtention de bons niveaux de rendement instantannés (parcelles précédées d’ananas ou d’une jachère principalement) ; iii) en absence totale de fertilisation, il résulte une diminution de l’activité biologique du sol mais aussi du rendement du plantain, exacerbé par le choix des précédents-culturaux (manioc ou banane plantain) en lien avec les contraintes pédoclimatiques et la maladie des raies noires (Cercosporiose noire) causée par Mycosphaerella fijiensis, notamment au sein des parcelles Haïtiennes ; iv) la succession plantain/plantain est la plus pénalisante vis-à-vis de la culture du plantain, car quelque soit le niveau d’intensification, le rendement reste relativement faible, en lien avec une dégradation de l’état sanitaire, comparativement aux autres précédents.
Plantain (Musa paradisiaca) is the staple food of millions of people worldwide and its cropping generates ongoing revenues for many farmers who are planting small or medium size areas. As in other tropical regions, plantain cultivation in Guadeloupe and Haiti is under heavy parasitic constraints terrestrial (plant-parasitic nematodes and banana weevil) as well as aerial (black Sigatoka in particular). Conventional means of control based on the use of synthetic products which adverse effects on the environment (soil, water, animals ...) as on human health are not bearable any more. It is thus urgent to think about agroecological solutions allowing to restore the biological balances, to maintain good soil quality and optimal plantain cropping systems.This is the ultimate goal of this thesis which couples the realization of an agroecological diagnosis in peasants’ plots, and the test of agroecological alternatives in semi-controlled conditions. To do this, a typology of plantain cropping systems was carried out from an agrienvironmental survey in the two study areas. It allowed to select 23 plots in Guadeloupe and 12 in Haiti in which an agroecological diagnosis was implemented. Based on this diagnosis and the research of agroecological alternatives to the use of chemicals, a field experiment was set up in Guadeloupe, in an experimental station allowing the test of three innovative practices for plantain cultivation (alone and combined), namely : i) the introduction of a cover-crop Paspalum notatum for weed control while reducing the use of herbicides ; ii) the input of worms’ compost to control plant-parasitic nematodes specific to plantain and to fertilize it ; iii) the use of healthy “PIF” plants (plants issued from stem fragments) free from telluric pests (nematodes and weevil’s larvaes).The typology of plantains cropping systems shows: i) in Guadeloupe the previous crops are: fallow pineapple and plantain predominate with a low level of intensification (low and infrequent chemical inputs) or high (high and frequent chemical inputs); ii) in Haiti, the previous crops are: fallow, plantain and cassava predominate with a low level or no intensification at all (no inputs). The results of the agroecological analysis show that : i) when the level of intensification is low, perennial plantain and pineapple as previous crops help maintaining a good soil quality and a good regulation of the telluric pests ; ii) when the level of intensification is strong, the soil engineers drastically reduce, while the density of telluric parasites increases without affecting good levels of instantaneous yields (plots where the previous crop is pineapple or mostly fallow) ; iii) when the fertilization is totally missing, it decreases the biological activity of the soil furthermore the plantain yields, exacerbated by the choice of the previous crop (cassava or plantain), in connection with soils and climate constraints and the black Sigatoka caused by Mycosphaerella fijiensis, especially in the Haitian plots ; iv) the crop succession plantain/plantain is the most critical regarding the plantain’s cropping, because whatever the level of intensification, the yields remain relatively low in connection with a degradation of the health state, compared to other previous crops.The driving of an experiment in a research station shows that on the scale of one year, the three tested innovative practices allow maintaining a good soils quality. Healthy plants "PIF" have a better health state (absence of plant parasitic nematodes in the roots) which helps a significant increase of the yields. Cover-crop P. notatum helps the weeds and the soil pests control and favors the improvement of soil biological activity and plantain yields. Worms’ compost contributes to the maintenance of a better soils quality while allowing the regulation of the populations of plant-parasitic nematodes of the plantains.

http://www.theses.fr/2014AGUY0758/document

Éditeur(s) : HAL CCSD Springer Verlag/EDP Sciences
Résumé : International audience
In the dense tropical rainforest understorey, saplings exhibit different growth strategies aiming at reaching light levels better fitting their ecology. Investing mainly in height growth, at the expense of their width, a lot are close to mechanical instability. Tachigali melinonii, a long living heliophilic tree species, is frequently observed to be extremely slender and supported by neighbours. Such observations suggest an active growth control through the perception of mechanical environment. * Mechanical environment or light availability, which one is the most influent on growth and slenderness (H/D)? To test this question, we recorded growth of control and staked saplings of two species with contrasting habits and ecology: T. melinonii, and Dicorynia guianensis, along a natural light gradient. * Dicorynia, the more stable, responded more clearly to the staking treatment, showing slenderness increase when light is available, whereas for Tachigali, only light availability governed growth. * For Tachigali, growth allocation is mainly governed by light availability and ontogeny, whereas Dicorynia is probably similar to the average tree strategy, using the thigmomorphogenetic physiological process to control its stability.
ISSN: 1286-4560

hal-00534019
https://hal.archives-ouvertes.fr/hal-00534019
DOI : 10.1051/forest/2009104

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The main purpose of this paper is to propose a deterministic mathematical model with control variable which describes the spatiotemporal spread of emph{Salmonella} within a laying flock. This model assume an indirect transmission of the disease within the flock through the bacteria density in the environment. We provide a mathematical analyze of the null controllability of the model: we begin to construct a family of solutions to the linear null-controllability problem using the the Carleman inequality. Then, by a generalized Leray-Shauder fixed point theorem, we show that one can bring the system to rest at final time T.
ISSN: 0307-904X

Droits : info:eu-repo/semantics/OpenAccess
hal-01683267
https://hal.univ-antilles.fr/hal-01683267
https://hal.univ-antilles.fr/hal-01683267/document
https://hal.univ-antilles.fr/hal-01683267/file/APM-S-13-02490-1.pdf

Éditeur(s) : HAL CCSD Blackwell Publishing
Résumé : International audience
In the Causses platform (south-east France), Late Hettangian to Sinemurian deposits were interpreted previously as shallow-water carbonate ramp deposits. A new look at these deposits has shown a fault-controlled mosaic carbonate platform that is different from the carbonate ramp models. Within the platform mosaic, 15 lithofacies have been recognized, which are organized in four facies associations, including peritidal, restricted shallow sub-tidal, sand dunes and sub-tidal shelf facies associations. The rapid lateral and vertical facies changes, and the lack of consistent landward or seaward direction indicated by the pattern of facies changes, question the existence of a shoreline suggested by the traditional models for this region. Instead, the facies organization and cycle stacking pattern suggest deposition in a mosaic of intertidal islands between which sub-tidal restricted or open conditions could coexist in very close proximity. Such a platform mosaic would have been defined by tectonic activities along normal faults which segmented the shallow-water Causses platform. The facies and facies associations are arranged into metre-scale, peritidal and sub-tidal cycles that are also variable. Certain cycles show the same stacking pattern in all the sections and seem to be traceable over tens of kilometres. On the contrary, other cycles cannot be correlated; they are present only in specific sections and have a maximum lateral extension of 1 or 2 km. These metre-scale cycles stack to form four medium-scale cycles bounded by surfaces that display sub-aerial exposure features. Medium-scale cycles stack into two larger-scale cycles (tens of metres thick) and are bounded by well-defined karstic surfaces. Based on their lateral continuity and their stacking pattern, the metre-scale cycles are controlled probably by high frequency eustatic variations overprinting the topographic irregularities formed by differential subsidence of fault-bounded blocks. Episodic fault activities may reorganize the topography so that, even if eustatic changes may still be the major control of cycles, the expression and number of cycles could be different. Cycles of medium and large-scale are interpreted as being allogenic, controlled by changes in eustasy and/or subsidence rates as evidenced by their lateral continuity and the correlations of the large-scale cycles with third-order depositional sequences.
ISSN: 1469-3496

hal-00411940
https://hal.archives-ouvertes.fr/hal-00411940
DOI : 10.1111/j.1365-3091.2007.00896.x

Éditeur(s) : Actes de la 8ème Conférence de l'IIFET (Marrakech, juillet 1996)
Résumé : In the framework of French-Brazil co-operation, the French Institute of research for exploitation of the sea (IFREMER), the State of Bahia and the company Littoral Sul Maricultura have developed a new technique for shrimp farming (Penaeus vannamei) using floating cages. After trials carried out during three years, this technique turns out very interesting from several viewpoints. The growth speed and the survival rate are very good, the negative effects on the environmental quality are weak and local fishermen have proved eager to adopt this technique as a part-time activity. In the same time, a technico-economic analysis, using a computerised simulation tool, as well as a market analysis in the State of Bahia have been carried out in order to assess the feasibility of such a project and to help research and development decisions. Despite low first investment and good biological results, the ex-farm production cost of shrimps weighing 15 g is as high as 4,5 US$ per kilo. This price is due to the low productivity of the labour and to the cost of nets which have a short life-time. It is possible to consider this activity as profitable on the market of Salvador de Bahia. Nevertheless, the question is how to face the international competition, which is particularly strong in the case of tropical shrimps. The conditions allowing enterprises to develop a strategy based on product quality and environmentally friendliness are reviewed. [NOT CONTROLLED OCR]
Dans le cadre de la coopération Franco-Brésilienne, l'IFREMER, l'Etat de Bahia et la société Littoral Sul Maricultura ont développé une nouvelle technique d'élevage de crevettes pénéides (Penaeus vannamei) en utilisant des cages flottantes. Après trois années de mise au point, cette technique s'est avérée intéressante sur plusieurs aspects. La vitesse de croissance et le taux de survie sont très satisfaisants, les effets négatifs sur la qualité du milieu naturel sont faibles et les pêcheurs locaux ont accueilli favorablement cette nouvelle pratique en complément de leur activité traditionnelle. Parallèlement, une analyse technico-économique utilisant un outil de simulation informatique ainsi qu'une analyse du marché de la crevette dans l'état de Bahia ont été conduites afin d'évaluer la faisabilité d'un tel projet et d'orienter les actions de recherche et développement. En dépit d'investissements initiaux plus faibles que dans les élevages en bassins et de bonnes performances zootechniques, le coût de production de crevettes de 15 g atteint 4,7 US$ par kilo. Dans les conditions de marché de l'Etat de Bahia, la rentabilité d'un projet d'élevage de crevettes en cage serait assurée, mais la faible productivité du travail et le coût de remplacement des filets ne permettent pas d'avoir des coûts de production aussi bas que dans les élevages en bassins. C'est pourquoi la question se pose de la possibilité pour ce type de production innovante d'affronter une concurrence internationale très forte comme dans le cas des crevettes tropicales. En particulier, les conditions dans lesquelles les entreprises peuvent développer une stratégie de compétitivité basée sur la qualité de leurs produits et sur le respect de l'environnement sont analysées. [OCR NON CONTRÔLE]

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1996/acte-4071.pdf
http://archimer.ifremer.fr/doc/00000/4071/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Transmission electron microscopy observations on olivine crystals deformed at moderate (≤1273 K) temperature evidenced dislocations interactions explaining the hardening observed in the experiments, but also recovery mechanisms by the absorption or emission of point defects. Thus we investigate the possibility that, at geological strain-rates, these recovery processes allow steady-state deformation by dislocation creep at low to moderate temperatures in the lithospheric mantle. We test this hypothesis using a 2.5-D dislocation dynamics (DD) model, which combines dislocation glide and recovery by climb. This model shows that diffusion-controlled recovery processes allow for steady-state deformation by dislocation creep in the lithospheric mantle at stresses <500 MPa. For stresses of 50–200 MPa, steady-state strain-rates of 10−15 s−110−15 s−1 may be attained at temperatures as low as 900 K. Fitting of the DD model produces a flow law, which represents a lower bound for the lithospheric mantle strength, since the models describe the deformation of an olivine single crystal in an easy slip orientation. Comparison of strain-rates and Moho temperatures inferred for different geodynamic environments and the predictions of this model-based flow law implies, nevertheless, that, except in incipient rifts, most of the observed deformation may be produced by stress levels ≤200 MPa, consistent with those inferred to be produced by convection. This convergence suggests that the present models, which explicitly calculate the time-dependent dislocation dynamics, may provide a correct first order estimate of the mechanical behaviour of the lithospheric mantle, which cannot be derived directly from any existing data.
ISSN: 0012-821X

hal-01277178
https://hal.archives-ouvertes.fr/hal-01277178
https://hal.archives-ouvertes.fr/hal-01277178/document
https://hal.archives-ouvertes.fr/hal-01277178/file/Boioli.pdf
DOI : 10.1016/j.epsl.2015.10.012

Éditeur(s) : HAL CCSD MAIK Nauka/Interperiodica
Résumé : Interaction between surface processes and deep tectonic processes plays a key role in the structural evolution, kinematics and exhumation of rocks in orogenic wedges. The deformation patterns observed in analogue models applied to natural cases of present active or ancient mountain belts reflect several first order processes that result of these interactions. Internal strain partitioning due to mechanical behaviour of a thrust wedge has a strong impact on the vertical component of displacement of tectonic units that in return favour erosion in domains of important uplift. Such strain partitioning is first controlled by tectonic processes, but surface processes exert a strong feed back on wedge dynamics. Indeed, material transfer in thrust wedges not only depends on its internal dynamics, it is also influenced by climate controlled surface processes involving erosion and sedimentation. Effects of erosion are multiple: they allow long term localization of deformed domains, they favour important exhumation above areas of deep underplating and combined with sedimentation in the foreland they contribute to maintain the wedge in a critical state for long time periods. The simple models illustrate well how mountain belts structure, kinematics of tectonic units and exhumation are determined by these complex interactions.
ISSN: 0016-8521

hal-00561361
https://hal.archives-ouvertes.fr/hal-00561361
DOI : 10.1134/S0016852110060075

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Seven male subjects volunteered to participate in an investigation of whether the diurnalincrease in core temperature influences the effects of pre-cooling or passivewarm-up on muscular power. Morning (07:00-09:00 h) and afternoon (17:00-19:00 h) evaluation of maximal power output during a cycling sprint was performed on different days in a control condition (room at 21.8 °C, 69% rh), after 30 min of pre-cooling in a cold bath (16 °C), or after 30 min of passivewarm-up in a hot bath (38 °C). Despite an equivalent increase from morning to afternoon in core temperature in all conditions (+0.4 °C, P < 0.05), power output displayed a diurnalincrease in control condition only. A local cooling or heating of the leg in a neutral environment blunted the diurnal variation in muscular power. Because pre-cooling decreases muscle power, force and velocity irrespective of time-of-day, athletes should strictly avoid any cooling before a sprint exercise. In summary, diurnal variation in muscle power output seems to be more influenced by muscle rather than core temperature.
ISSN: 1440-2440

hal-00706159
https://hal.univ-antilles.fr/hal-00706159
DOI : 10.1016/j.jsams.2007.09.008

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The mangrove swamp environment constitutes a sulphide rich habitat harbouring some thioautotrophic organisms. The ciliate Zoothamnium niveum and the nematode Eubostrichus dianae, both known to live associated with bacterial sulphide-oxidizing ectosymbionts, were analysed as positive controls by Raman microspectrometry. The detection of the 3 Raman bands characteristic of elemental sulphur (S8) allows us to define a positive model of sulphide-oxidizing symbiotic invertebrates and by extrapolation, of thioautotrophic organisms. A fast screening using this tool was carried out on eukaryotic organisms such as hydrozoan, nematodes, annelids, copepods, and ciliate (Pseudovorticella sp.) and on free-living filamentous bacteria found on decomposing leaves in order to detect thioautotrophic organisms. The Raman microspectrometry permits us: (i) to reveal thioautotrophic metabolism of free-living bacteria (Beggiatoa sp.) and even for Archaea and (ii) to detect sulphide-oxidizing endosymbiotic and ectosymbiotic bacteria associated with the Bivalve Lucina pectinata and Pseudovorticella sp., respectively. Raman microspectrometry represents a fast, easy and non destructive technique which can be used on living organisms without constraints of sample size. The Raman analysis can also be completed by ultrastructural analysis (SEM, TEM) on the same sample.
ISSN: 0141-1136

hal-00715329
https://hal.univ-antilles.fr/hal-00715329
DOI : 10.1016/j.marenvres.2010.02.001

Éditeur(s) : HAL CCSD
Résumé : Background. Chlorine is the most widely used disinfectant for drinking water treatment. During treatment process, the natural organic matter present in water reacts with chlorine to form disinfection by-products (DBPs), such as trihalomethanes (THMs) and haloacetic acids (HAAs), the most occurring ones. Several identified DBPs were recognized carcinogens or fetotoxic in animals. We conducted two epidemiological studies to assess the health effects of human exposure to DBPs regarding cancer and reproduction. Association between THM exposure and the risk of bladder cancer: a pooled analysis of 3 European case-control studies. The study included 2381 cases and 3086 controls from 3 case-control studies (France, Finland, Spain). Environmental exposure to SPCs was measured by THM concentrations in water distribution systems, retrospectively estimated through the 40-year exposure window. Information about water uses (tap water ingestion, showers and baths, swimming-pool attendance) was available. An increased risk of bladder cancer was observed, in men only, with increasing THM concentrations in water systems and duration of exposure to chlorinated surface water. No association was observed with exposure through tap water ingestion. Exposure through showers, baths and swimming in pools (available in Spanish study only) was associated with an increased risk of bladder cancer. Three North-American case-control studies were joined to the three European ones into a meta-regression. No specific dose-response relationship was identified for European studies. A global dose-response relationship was consequently estimated, including 4351 cases and 7055 controls. Association between DBP exposure and the risk of preterm birth and Intra-Uterine Growth Retardation (IUGR). This study was conducted within the PELAGIE cohort (3400 pregnant women included in early pregnancy, in Brittany, France, between 2002 and 2006). Exposure during pregnancy was measured by 2 indicators: THM concentrations in water distribution systems and a biomarker of HAA ingestion, the level of trichloroacetic acid in maternal urine at inclusion (in a nested case-control study). The regulatory database SISE-Eaux was used to estimate THMs concentrations in the water distribution systems. Water uses during pregnancy (ingested tap water, swimming-pool attendance, showers and bath frequencies and duration) were collected with questionnaires. Our results suggest an association between prenatal exposure to DBPs (THMs and HAAs) and the risk of IUGR. No association was found with the risk of preterm birth.
Contexte. La chloration est le traitement le plus utilisé pour désinfecter l’eau distribuée à la population. Lors du traitement, des sous-produits de chloration (SPCs) se forment par réaction de la matière organique naturelle présente dans l’eau avec le chlore. Les produits les plus présents sont les trihalométhanes (THMs), les acides haloacétiques (HAAs). Des études toxicologiques (animales et in vitro) ont montré la génotoxicité et/ou carcinogénicité et la reprotoxicité de certains SPCs. Nous avons mené deux études évaluant les effets sur la santé humaine de l’exposition aux SPCs, dans le domaine du cancer et de la reproduction. Association entre exposition aux THMs et risque de cancer de la vessie : une analyse poolée de 3 études cas-témoins européennes. Cette analyse a inclus 2381 cas et 3086 témoins issus de 3 études cas-témoins (France, Espagne, Finlande). L’exposition environnementale aux SPCs a été mesurée par la concentration en THMs estimée rétrospectivement dans les réseaux de distribution d’eau au cours des 40 années de la fenêtre d’exposition. Les usages de l’eau connus sont l’ingestion, les douches et les bains, la fréquentation de piscine (étude espagnole seulement). Une relation croissante a été observée entre le niveau environnemental de THMs, la durée d’exposition à une eau de surface chlorée et le risque de cancer de la vessie, chez les hommes uniquement. Aucune association n’a été observée avec l’exposition via l’ingestion d’eau du robinet. L’exposition via les douches, les bains et la piscine est apparue liée au risque de cancer de la vessie. Trois études cas-témoins nord-américaines ont été intégrées dans une méta-régression. Aucune spécificité européenne de la relation dose-réponse n’a été mise en évidence. Une relation dose-réponse globale incluant 4351 cas et 7055 témoins a été estimée. Association entre exposition aux SPCs et risque de prématurité et de retard de croissance intra-utérin (RCIU). Cette étude est issue de la cohorte bretonne Pélagie (3400 femmes enceintes recrutées en début de grossesse entre 2002 et 2006). L’exposition pendant la grossesse a été mesurée à l’aide de 2 indicateurs : la concentration en THMs de l’eau distribuée dans les réseaux et le dosage d’un biomarqueur urinaire (acide trichloroacétique) pour un sous-échantillon de femmes (étude cas-témoins nichée). Les niveaux dans les réseaux proviennent de la base de données réglementaire SISE-Eaux. Les usages de l’eau du robinet par les femmes pendant la grossesse ont été collectés par questionnaire (quantité d’eau du robinet bue, fréquentation de la piscine, fréquence et durée des douches et des bains). Notre étude suggère une association entre l’exposition prénatale aux SPCs et le risque de RCIU. Aucune association n’est observée avec le risque de prématurité.
https://tel.archives-ouvertes.fr/tel-00927735

Droits : info:eu-repo/semantics/OpenAccess
NNT : 2013REN1B008
tel-00927735
https://tel.archives-ouvertes.fr/tel-00927735
https://tel.archives-ouvertes.fr/tel-00927735/document
https://tel.archives-ouvertes.fr/tel-00927735/file/COSTET_DEIBER_Nathalie4.pdf

Résumé : The increase in the number of marinas and the problems that they pose has prompted Ifremer to analyse the consequences of these structures on the coastal environment. This report reviews the impacts associated with the construction and the operation of marinas. Some simple measures are proposed to reduce the inconveniences and ensure the compatibility of pleasure boating with other traditional activities. Most of all, these measures seek to reconcile the existence of marinas with environmental protection. This report is intended, in particular, for spatial planners and those responsible for protecting the coastal environment: representatives of administrative bodies; national, local, county ("department") and regional governments; organisations and associations in charge of environmental conservation.
La multiplication des ports de plaisance et les problèmes qu'ils posent ont incité l'Ifremer à analyser les conséquences de ces constructions sur le milieu littoral. L'ouvrage présenté passe en revue les impacts liés à la construction et à l'exploitation du port. Il propose quelques mesures simples qui visent à réduire les nuisances et assurer la compatibilité de la plaisance avec les autres activités traditionnelles. Et, surtout, il cherche à concilier l'implantation du port avec la protection de l'environnement. Cet ouvrage s'adresse, en particulier, à toutes les personnes qui ont des responsabilités dans la protection et l'aménagement du littoral: représentants de l'État, de l'Administration, des municipalités, des départements, des régions, organismes et associations chargés de sa sauvegarde. [OCR NON CONTRÔLE]

Droits : Institut français de recherche pour l'exploitation de la Mer, IFREMER, 1991
http://archimer.ifremer.fr/doc/1991/rapport-4460.pdf
http://archimer.ifremer.fr/doc/00000/4460/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Predicting the impact of underground engineering on the environment requires the knowledge of natural media at different scales. In particular, understanding basic phenomena controlling the properties of rocks in the presence of complex fluids necessitates a detailed atomic description of the solid/fluid/solid contacts, the subject of Part I of the present study. First, building the solid interspace between two different crystals in a non-periodic situation is achieved using the ab initio and molecular mechanics code GenMol (TM). A description of the fluid confined within the interspace is then derived from the original genetic iterative multi-species (GIMS) algorithm implemented in the same code. This approach consists of equilibrating chemical potentials, cycle after cycle and species after species, between the confined fluid and the free natural fluid. An elementary iteration for a species k consists of different steps incrementing the number N-k of particles k, with other numbers N-k remaining constant. At each step, an optimum fluid composition is obtained by a genetic process distributing the fluid particles on a grid by stochastic shots, followed in fine by a refining process. The effectiveness of the GIMS approach is demonstrated in the case study of a fluid confined between two (0 0 1) kaolinite faces, with apertures h varying between 4 and 10 A. connected to a 9-species external solution [H2O, Cl-, Na+ CO2(aq), NaCl(aq), Ca2+, Mg2+, HCO3-, H3O+] where concentrations are ranging from 55 to 10(-4) mol/L. The results show a drastic variation in the solute/solvent and cations/ions ratios in the confined fluid when aperture h is lowered to less than 1 nm. These results obtained with a very rapid convergence of the iterative algorithm combined with a very competitive genetic optimizer are validated with high precision on a free solution. This description of contacts between crystals is original and unattainable by standard crystal interface approaches. It opens the way to understanding and/or predicting phenomena between crystals in a complex natural environment, such as adhesion or repulsion investigated in the Part II of this study.
ISSN: 0022-0248

hal-00544569
https://hal.archives-ouvertes.fr/hal-00544569
DOI : 10.1016/j.jcrysgro.2010.08.009

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The susceptibility of Anopheles mosquitoes to Plasmodium infections relies on complex interactions between the insect vector and the malaria parasite. A number of studies have shown that the mosquito innate immune responses play an important role in controlling the malaria infection and that the strength of parasite clearance is under genetic control, but little is known about the influence of environmental factors on the transmission success. We present here evidence that the composition of the vector gut microbiota is one of the major components that determine the outcome of mosquito infections. A. gambiae mosquitoes collected in natural breeding sites from Cameroon were experimentally challenged with a wild P. falciparum isolate, and their gut bacterial content was submitted for pyrosequencing analysis. The meta-taxogenomic approach revealed a broader richness of the midgut bacterial flora than previously described. Unexpectedly, the majority of bacterial species were found in only a small proportion of mosquitoes, and only 20 genera were shared by 80% of individuals. We show that observed differences in gut bacterial flora of adult mosquitoes is a result of breeding in distinct sites, suggesting that the native aquatic source where larvae were grown determines the composition of the midgut microbiota. Importantly, the abundance of Enterobacteriaceae in the mosquito midgut correlates significantly with the Plasmodium infection status. This striking relationship highlights the role of natural gut environment in parasite transmission. Deciphering microbe-pathogen interactions offers new perspectives to control disease transmission.
ISSN: 1553-7366

hal-01546176
https://hal.archives-ouvertes.fr/hal-01546176
DOI : 10.1371/journal.ppat.1002742

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Le Costa Rica est devenu une référence incontournable sur le plan de l’écotourisme et de la conservation de l’environnement depuis une quinzaine d’années. Le pays est « célèbre pour son approche éclairée de la préservation de l’environnement ». Environ 27 % de la superficie du pays est protégée et les parcs nationaux couvrent plus de 13 % du territoire costaricien. À travers l’analyse des processus de développement du tourisme, l’exemple du Costa Rica démontre l’importance des facteurs politiques et du contrôle des images dans la mise en tourisme d’un lieu.
Costa Rica has become an essential reference point in terms of ecotourism and conservation of the environment over the past fifteen years. The country became famous for its original policy to preserve the environment. Approximately 27% of the country's land is protected and national parks cover more than 13% of the Costa Rican territory. An analysis of the Costa Rican approaches to the development of tourism, provides an example of the importance of political factors and the control of “image” in the popular and public imagination.
Costa Rica

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.432
http://journals.openedition.org/etudescaribeennes/432

Éditeur(s) : HAL CCSD
Résumé : International audience
Background: We examined the association between exposure during pregnancy to trihalomethanes, the most common water disinfection by-products, and birth outcomes in a European cohort study (Health Impacts of Long-Term Exposure to Disinfection By-Products in Drinking Water). We took into account exposure through different water uses, measures of water toxicity, and genetic susceptibility. Methods: We enrolled 14,005 mothers (2002-2010) and their children from France, Greece, Lithuania, Spain, and the UK. Information on lifestyle- and water-related activities was recorded. We ascertained residential concentrations of trihalomethanes through regulatory records and ad hoc sampling campaigns and estimated route-specific trihalomethane uptake by trimester and for whole pregnancy. We examined single nucleotide polymorphisms and copy number variants in disinfection by-product metabolizing genes in nested case-control studies. Results: Average levels of trihalomethanes ranged from around 10 μg/L to above the regulatory limits in the EU of 100 μg/L between centers. There was no association between birth weight and total trihalomethane exposure during pregnancy (β = 2.2 g in birth weight per 10 μg/L of trihalomethane, 95% confidence interval = 3.3, 7.6). Birth weight was not associated with exposure through different routes or with specific trihalomethane species. Exposure to trihalomethanes was not associated with low birth weight (odds ratio [OR] per 10 μg/L = 1.02, 95% confidence interval = 0.95, 1.10), small-for-gestational age (OR = 0.99, 0.94, 1.03) and preterm births (OR = 0.98, 0.9, 1.05). We found no gene-environment interactions for mother or child polymorphisms in relation to preterm birth or small-for-gestational age. Conclusions: In this large European study, we found no association between birth outcomes and trihalomethane exposures during pregnancy in the total population or in potentially genetically susceptible subgroups. © 2016 Wolters Kluwer Health, Inc.
Epidemiology

hal-01392115
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01392115
DOI : 10.1097/EDE.0000000000000544
PUBMED : 27468006

Éditeur(s) : HAL CCSD
Résumé : International audience
The published literature related to distributed parameter systems theory is quite large, and it is not feasible in a single book to give a detailed review on the wide historical development of all of it. Our choice of what to cover was motivated by the following consideration. Since distributed parameter systems evolve in time and space, the research investigations on their analysis and control focus on considering the whole system domain for any study. We feel strongly that within this research field, animportant consideration was missing; that of considering that the system may give raise to prescribed subdomains (regions) where one has to achieve an objective. This is the case of so many applications ranging from engineering to life sciences. For that reason, covering classical prerequisite in analysis and control areas, we have devoted the book to the extension of the classical distributed parameter results to regional ones.Students of mathematics do not come into contacts with distributed parameter systems during their classes. They are introduced to them when they start research and often they are influenced by the knowledge and the advice of experimented scientists. This was our case at the very beginning of these research investigations in the mid 70’s. We would liketo express our special thanks to many of them and mainly late Professor Anthony J. Pritchard (University of Warwick, GB) and late Professor J.L. Lions (College de France) who were so encouraging in front of our determination in driving an academic carrier. We also express our thanks to our co-workers and research students. We wish to acknowledge the feedback from all those who took courses based on various parts of this book.This book may be used by graduate students in mathematics, engineering, physics, and even by students from other fields such as life or environmental sciences. This book may also be used as an information source for researchers and education professionals. We assume that the readers already know the basic concepts of analysis and control of distributedparameter systems.
https://hal.archives-ouvertes.fr/hal-01297188

ISBN : 978-2-35412-140-2
hal-01297188
https://hal.archives-ouvertes.fr/hal-01297188

Éditeur(s) : HAL CCSD
Résumé : International audience
Home health care workers interventions have been implemented in western countries to improve health status of patients with respiratory diseases especially asthma and allergic illnesses. Twenty-six controlled studies dealing with prevention and control of these diseases through home environmental interventions were reviewed. After a comprehensive description of the characteristics of these studies, the effectiveness of each intervention was then evaluated in terms of participants' compliance with the intervention program, improvement of quality of the indoor environment, and finally improvement of health outcomes, in detailed tables. Limitations and biases of the studies are also discussed. Overall, this review aims at giving a toolbox for home health care workers to target the most appropriate measures to improve health status of the patient depending on his and/or her environment and disease. Only a case-by-case approach with achievable measures will warrant the efficacy of home interventions. This review will also provide to the research community a tool to better identify targets to focus in future evaluation studies of home health care workers action.
Journal of allergy and clinical immunology. In practice

hal-01477202
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01477202
DOI : 10.1016/j.jaip.2016.07.011
PUBMED : 27665387