Éditeur(s) : Pergamon-elsevier Science Ltd
Résumé : The present work aimed at better understanding metal and metalloid bioaccumulation in the edible Pacific blue shrimp Litopenaeus stylirostris, using both laboratory and field approaches. In the laboratory, the bioaccumulation kinetics of Ag, Cd, Co, Cr, and Zn have been investigated in shrimp exposed via seawater and food, using the corresponding gamma-emitting radiotracers (Ag-110m, Cd-109, Co-57, Cr-51, and Zn-65) and highly sensitive nuclear detection techniques. Results showed that hepatopancreas and intestine concentrated the metals to the highest extent among the blue shrimp organs and tissues. Moulting was found to play a non negligible detoxification role for Co, Cr and, to a lesser extent, Zn. Metal retention by L stylirostris widely varied (from a few days to several months), according to the element and exposure pathway considered (a given metal was usually less strongly retained when ingested with food than when it was taken up from the dissolved phase). In the field study, Ag, As, Cd, Co, Cr, Cu, Mn, Ni, and Zn were analysed in shrimp collected from a New Caledonian aquaculture pond. Metal concentrations in the shrimp muscles were generally relatively low and results confirmed the role played by the digestive organs and tissues in the bioaccumulation/storage/detoxification of metals in the Pacific blue shrimp. Preliminary risk considerations indicate that consumption of the shrimp farmed in New Caledonia is not of particular concern for human health. (C) 2010 Elsevier Ltd. All rights reserved.
Marine Pollution Bulletin (0025-326X) (Pergamon-elsevier Science Ltd), 2010 , Vol. 61 , N. 7-12 , P. 576-584

Droits : 2010 Elsevier Ltd All rights reserved.
http://archimer.ifremer.fr/doc/00014/12528/9869.pdf
DOI:10.1016/j.marpolbul.2010.06.035
http://archimer.ifremer.fr/doc/00014/12528/

Éditeur(s) : HAL CCSD Institut d'Histoire de la Révolution française
Résumé : International audience
At the peak of the second colonial Empire, citizenship there has three essential characteristics: it is fragmented by diverse forms of hierarchisation of the electorate ; it is reserved solely for nationals of the colonial Empire, the French and natives within a differentiated conception of nationality ; it is marked by the idea of civilisation. This situation came about in several stages: in 1978, specific citizenship is devised to civilise the newly freed; between 1848 and 1870, in Algeria there is some experimentation with local citizenship for the French, foreigners and natives, but this was abandoned; between 1870 and 1898, local citizenship is devised, expanded to include national elections for the natives of French India, whilst with the Algerian financial delegations, the “representation of interests” is accompanied by French citizenship without the right to participate in local elections.
Dans le second Empire colonial à son apogée, la citoyenneté a trois caractéristiques essentielles : elle est fragmentée par diverses formes de hiérarchisation quant à l’électorat ; elle est réservée aux seuls ressortissants de l’Empire colonial, les Français et les indigènes, dans le cadre d’une conception différenciée de la nationalité ; elle est marquée par l’idée de civilisation. Cette situation est née en plusieurs étapes : en 1798, on conçoit une citoyenneté spécifique pour civiliser les nouveaux libres ; entre 1848 et 1870, en Algérie, on expérimente puis abandonne une citoyenneté locale pour les Français, les étrangers et les indigènes ; entre 1870 et 1898, on conçoit une citoyenneté locale élargie aux élections nationales pour les natifs de l’Inde française, alors qu’avec les délégations financières algériennes, la « représentation des intérêts » s’accompagne d’une citoyenneté française amputée du droit de participer à une élection locale.
ISSN: 2105-2557

hal-01620584
https://hal.archives-ouvertes.fr/hal-01620584
DOI : 10.4000/lrf.1460

Éditeur(s) : Elsevier
Résumé : As top predators of pelagic food webs, large fish naturally bioaccumulate mercury (Hg). Determining Hg burdens in commercialized fish is essential considering the concern about effects of contaminants on human health and the legal thresholds that are therefore set for local consumption and/or exportation. Total Hg levels were measured in the muscular tissue of 183 fish of five commercially important species from the tropical zone of the Western Indian Ocean. All individuals were measured and sexed in order to study the impregnation of Hg with size and sex within each species. Values of Hg found in this part of the Indian Ocean were comparable to Hg in muscular tissue of the same species studied in other areas. The highest Hg levels were noted in Swordfish (Xiphias gladius) caught in waters surrounding Reunion Island (3.97 +/- 2.67 mu g g(-1) dry weight). Following the Swordfish, in decreasing order of Hg content, were the Yellowfin Tuna (Thunnus albacares) and the Skipjack (Katsuwonus pelamis), then the Common Dolphinfish (Coryphaena hippurus) and the Wahoo (Acanthocybium solandri). In the North of the Mozambique Channel, Swordfish had higher Hg levels than Yellowfin Tunas, and Dolphinfish exhibited intermediate Hg levels. The size of a fish was a determining factor of its Hg burden, as was the species. Differences in size-normalized Hg levels were observed between the two study zones for Swordfish and Common Dolphinfish. Sex, in contrast, did not influence Hg levels suggesting that females and males have similar feeding habits. The muscular Hg levels presented here suggest that consumers of fish originating from the Western Indian Ocean should limit themselves to one Swordfish based meal per week, or one fish meal a day if they choose to eat tuna or Common Dolphinfish. (c) 2006 Elsevier B.V. All rights reserved.
The Science of The Total Environment (0048-9697) (Elsevier), 2006-08 , Vol. 366 , N. 2-3 , P. 688-700

Droits : 2006 Elsevier
http://archimer.ifremer.fr/doc/2006/publication-1862.pdf
DOI:10.1016/j.scitotenv.2006.02.006
http://archimer.ifremer.fr/doc/00000/1862/

Éditeur(s) : HAL CCSD IOS Press
Résumé : International audience
Cancer is generally conceived as a dedifferentiation process in which quiescent post-mitotic differentiated cells acquire stem-like properties and the capacity to proliferate. This view holds for the initial stages of carcinogenesis but is more questionable for advanced stages when the cells can transdifferentiate into the contractile phenotype associated to migration and metastasis. Singularly from this perspective, the hallmark of the most aggressive cancers would correspond to a genuine differentiation status, even if it is different from the original one. This seeming paradox could help reconciling discrepancies in the literature about the pro-or anti-tumoral functions of candidate molecules involved in cancer and whose actual effects depend on the tumoral grade. These ambiguities which are likely to concern a myriad of molecules and pathways, are illustrated here with the selected examples of chromatin epigenetics and myocardin-related transcription factors, using the human MCF10A and MCF7 breast cancer cells. Self-renewing stem like cells are characterized by a loose chromatin with low levels of the H3K9 trimetylation, but high levels of this mark can also appear in cancer cells acquiring a contractile-type differentiation state associated to metastasis. Similarly, the myocardin-related transcription factor MRTF-A is involved in metastasis and epithelial-mesenchymal transition, whereas this factor is naturally enriched in the quiescent cells which are precisely the most resistant to cancer: cardiomyocytes. These seeming paradoxes reflect the bistable epigenetic landscape of cancer in which dedifferentiated self-renewing and differentiated migrating states are incompatible at the single cell level, though coexisting at the population level. © 2016-IOS Press and the authors. All rights reserved.
ISSN: 0888-6008

hal-01367146
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01367146
DOI : 10.3233/BD-150210
PUBMED : 27177343

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Cet article vise à mener une analyse juridique du concept de mondialisation. Alors que la mondialisation est souvent décriée comme anti-démocratique, nous démontrerons que d’un point de vue strictement juridique, il apparaît que la réalité est plus nuancée. Nous passerons en revue les critiques de la mondialisation liées à la perte de souveraineté de l’Etat, qui nous paraissent devoir être relativisées à la fois dans son étendue et dans son impact sur la démocratie. Nous montrerons comment le droit international surmonte ces difficultés en permettant un nouvel équilibre entre Etat et individu sur la scène internationale, et comment à un modèle de démocratie traditionnel fondé sur l’Etat est en train de succéder une démocratie fondée sur la société civile transnationale. Enfin, nous évoquerons le rôle essentiel du juge afin de préserver démocratie et état de droit dans l’ordre international, malgré les limites qui lui sont inhérentes.
This article aims to critically analyse the concept of globalization, from a legal standpoint. While globalization is often criticized as anti-democratic, we demonstrate that from a strictly legal point of view, the reality is subtler. We review the criticisms of globalization related to the loss of state sovereignty, which we believe need to be put into perspective in both their extent and their impact on democracy. We show how international law overcomes the new challenges due to globalization by allowing a new balance between the State and the Individual on the international plane. We then show that the classical model of democracy based on the State is being superseded by a democracy based on transnational civil society. Finally, we discuss the essential role of the judge to preserve democracy and rule of law in the international order, despite the limitations inherent to his competences.

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5876
http://journals.openedition.org/etudescaribeennes/5876

Éditeur(s) : Elsevier Science Bv
Résumé : Monitoring fish and underwater habitats, particularly in and around marine protected areas (MPAs) requires non-destructive observation methods. This is generally achieved by divers conducting underwater visual censuses (UVC), but video-based techniques are now being used more often to observe underwater macrofauna and habitats. A comparison of these two techniques is relevant with the development of high-definition (HD) video, which constitutes a substantial improvement over previously available video resolutions at limited extra cost. We conducted a paired observation experiment involving both HD video and UVC in an MPA located in the New Caledonian lagoon, which is a highly diversified coral reef ecosystem. We compared three techniques for counting fish along 50 m x 4 m delineated strip transects: UVC and two video techniques in which the diver used either a straight trajectory (I-type transect) or a browsing one (S-type transect). The results showed that the proportion of fish that were not identified up to the species level did not exceed 3.3% in video observations versus 1.7% in UVC. The abundance and species richness were larger in UVC than in videos, and S-type transects detected more individuals and species than I-type transects. The average abundance and species richness observed by UVC were 1094 individuals and 69.7 species per transect respectively. In comparison with UVC. I-type and S-type video transects detected on average 56% and 61% of the abundance and 85% and 77% of the species richness seen by UVC respectively. Our results showed that, in comparison to UVC data recorded in situ, the post field analysis of HD video images provided representative observations of fish abundance and species diversity, although fewer species and individuals were detected. The advantages and shortcomings of each observation technique for monitoring fish assemblages, particularly in an MPA are discussed. HD video appears to be a cost-effective technique in terms of the human resources and time needed for field implementation. Overall, this study suggests that HD video-based techniques constitute an interesting complement to UVC, or an alternative when these cannot be implemented. (C) 2010 Elsevier B.V. All rights reserved.
Fisheries Research (0165-7836) (Elsevier Science Bv), 2011-01 , Vol. 107 , N. 1-3 , P. 84-93

Droits : 2010 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/00031/14192/11470.pdf
DOI:10.1016/j.fishres.2010.10.011
http://archimer.ifremer.fr/doc/00031/14192/

Éditeur(s) : HAL CCSD Elsevier
Résumé : 00000 ăWOS:000386415300011
International audience
Highly biologically active marine sesquiterpene ilimaquinone was selected for chemical modifications. Its biotransformation was investigated using a combinatorial approach as an original way to screen different strains of microorganisms. Mucor circinelloides ATCC 8541 was able to structurally modify ilimaquinone into three different compounds. A stereospecific epoxidation was observed and compared to chemical epoxidation. A hydroxylation of the decalin ring was also observed as well as an unexpected substitution on the quinone ring by ethanolamine. Compounds were evaluated against several cell lines. (C) 2016 Elsevier Ltd. All rights reserved.
ISSN: 0040-4039

hal-01483185
https://hal.archives-ouvertes.fr/hal-01483185
DOI : 10.1016/j.tetlet.2016.09.075

Éditeur(s) : HAL CCSD
Résumé : International audience
In French Guiana, located on the northeastern coast of South America, bats of different species are very numerous. The infection of bats and their ticks with zoonotic bacteria, especially Rickettsia species, is so far unknown. In order to improve knowledge of these zoonotic pathogens in this French overseas department, the presence and diversity of tick-borne bacteria was investigated with molecular tools in bat ticks. In the beginning of 2013, 32 bats were caught in Saint-Jean-du-Maroni, an area close to the coast of French Guiana, and the ticks of these animals were collected. A total of 354 larvae of Argasidae soft ticks (Ornithodoros hasei) from 12 bats (Noctilio albiventris) were collected and 107 of them were analysed. DNA was extracted from the samples and quantitative real-time PCR was carried out to detect Rickettsia spp., Bartonella spp., Borrelia spp. and Coxiella burnetii. All tested samples were negative for Bartonella spp., Borrelia spp. and Coxiella burnetii. Rickettsia DNA was detected in 31 (28.9%) ticks. An almost entire (1118 base pairs long) sequence of the gltA gene was obtained after the amplification of some positive samples on conventional PCR and sequencing. A Bayesian tree was constructed using concatenated rrs, gltA, ompA, ompB, and gene D sequences. The study of characteristic sequences shows that this Rickettsia species is very close (98.3-99.8%) genetically to R. peacockii. Nevertheless, the comparative analysis of sequences obtained from gltA, ompA, ompB, rrs and gene D fragments demonstrated that this Rickettsia is different from the other members of the spotted fever group. The sequences of this new species were deposited in GenBank as Candidatus Rickettsia wissemanii. This is the first report showing the presence of nucleic acid of Rickettsia in Ornithodoros hasei ticks from South American bats. (C) 2016 Elsevier GmbH. All rights reserved.
TICKS AND TICK-BORNE DISEASES

hal-01459758
https://hal.archives-ouvertes.fr/hal-01459758
DOI : 10.1016/j.ttbdis.2016.09.004

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: Adolescent obesity is prevalent in Pacific region ethnic groups (European, Melanesian and Polynesian) living in both urban and rural areas. Although body perception is an important factor of weight gain or loss, little is known about the body self-perceptions of Pacific region adolescents. This study therefore evaluated adolescent perceptions of body weight according to ethnicity (European, Melanesian or Polynesian), socioeconomic status (low, intermediate or high) and living area (rural or urban) in New Caledonia.Methods: Sociodemographic and anthropomorphic data from 737 adolescents (351 boys and 386 girls) with ages ranging from 11 to 16 years were collected and analysed. The International Obesity Task Force (IOTF) standards were used to define weight status as normal-weight, underweight or overweight/obese. Weight perception was assessed from detailed questionnaires, with adolescents rating their own weight with the following descriptors: 'about the right weight', 'too heavy', or 'too light'.Results: Results showed that only 8.5% of normal-weight adolescents (7% boys and 10% girls) identifying themselves as ‘too heavy’. Normal-weight Melanesian adolescents were less likely than their European counterparts to assess themselves as too heavy (OR = 0.357). However, half the overweight/obese adolescents underestimated their weight status (53% boys and 48% girls). Weight misperception was associated with ethnicity, socioeconomic status and living area, with gender-specific differences.Conclusions: The results of this study suggest that these sociodemographic factors should be taken into account when designing public health policies and health education school programmes in New Caledonia and, more broadly, the Pacific regio
ISSN: 1471-2458

Droits : info:eu-repo/semantics/OpenAccess
hal-01678909
https://hal.univ-antilles.fr/hal-01678909
https://hal.univ-antilles.fr/hal-01678909/document
https://hal.univ-antilles.fr/hal-01678909/file/Misperception%20of%20weight%20status%20in%20the%20pacific-%20preliminary%20findings%20in%20rural%20and%20urban%2011-%20to%2016-year-olds%20of%20New%20Caledonia%20Ste%CC%81phane%20Frayon%20et%20al%202017.pdf
DOI : 10.1186/s12889-016-3982-0

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : La relation du tourisme à la pauvreté conduit à envisager celle-ci comme objet de droit, i.e. d’une régulation juridique conçue et modulée en considération des objectifs recherchés, quant au contenu et à l’efficacité de la norme. Le traitement juridique de la pauvreté connaît toutefois des limites, en raison des difficultés techniques et conceptuelles auxquelles se heurte l’instrumentalisation juridique des politiques de lutte contre la pauvreté, au plan formel comme à celui des principes généraux du droit afférents aux conditions de vie et à la dignité des individus et des groupes. Il convient alors d’apprécier les apports comme les limites de la régulation du tourisme comme instrument de lutte contre la pauvreté, à la fois quant à la contribution qu’un tourisme maîtrisé peut apporter à sa réduction, et quant aux excès d’un tourisme de masse porteur de facteurs de déstructuration culturelle et de désintégration sociétale au détriment des plus défavorisées.
The relationship of tourism to poverty leads us to consider it as an object of law, i.e. a legal regulation designed in consideration of the objectives sought, on the content and effectiveness of the legal standard.However, the legal treatment of poverty knows limits, due to technical and conceptual challenges facing the legal manipulation of policies against poverty. This applies to the formal level as that of the general principles of law relating to living conditions and dignity of individuals and groups.It should then assess the contributions and limits in the regulation of tourism as a tool to fight poverty, both in terms of the contribution that tourism can make toward reducing poverty, and in terms of the excesses of tourism and cultural disintegration of society at the expense of marginalized, poor populations.

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.6509
http://journals.openedition.org/etudescaribeennes/6509

Éditeur(s) : HAL CCSD
Résumé : Some States host Open Registers (also known under the pejorative term of “flags of convenience”): ships are registered regardless of their actual owners’ nationality or residence, and thus States enable them to escape from their country of origin’s legal framework. By being an aspect of globalization, this phenomenon has been growing up for 30 years, and is nowadays widespread, or even universal. Because each State fixes the conditions for implementation of its right to register ships, the phenomenon is a legal one. But it has strong economic implications too. Indeed, the laws of the State of registration – namely “flag state” – determine certain costs or some advantages for the company that adopts it, and can be attractive or repellent as for them.This work proposes an economic reading of the open registers of ships as a recent object of economics and tries to highlight the contribution of this activity to small islands’ economies, especially through some Caribbean examples (the Caribbean is by the way the historical cradle of this activity and offshore financial centres).Based on data concerning the last 30 years and 7 open-registry countries of the Caribbean (Gross Domestic Products and some items of the balances of payments), the research conducted here shows that, except perhaps Antigua, no significant correlation exists in host countries between the fleets registered and the economic gains : the “open registration” is not, by itself, a gain for small island economies surveyed.
Certains Etats pratiquent la libre immatriculation, également connue sous le terme péjoratif de « pavillons de complaisance » : ils enregistrent des navires chez eux sans considération de la nationalité ou de la résidence effective des propriétaires, et leur permettent ainsi d’échapper au cadre légal de leur pays d’origine. Aspect de la mondialisation, le phénomène qui a pris de l’ampleur dans les 30 dernières années est aujourd’hui largement répandu, voire universel.Au-delà des aspects juridiques (chaque Etat organise son droit à immatriculer les navires), la libre immatriculation a des conséquences économiques fortes car la législation de l’Etat d’immatriculation – dit « Etat du pavillon » – détermine certains coûts ou certaines facilités pour l’entreprise qui l’adopte.Le présent travail propose une lecture de la libre immatriculation des navires en tant qu’objet récent de la science économique et tente, à ce titre, de lever le voile sur la portée de cette activité sur les pays d’accueil, en prenant le cadre restreint de petites économies insulaires de la Caraïbe, berceau historique de cette activité et des centres financiers offshore.Sur la base de données économiques sur 30 ans concernant 7 pays de libre immatriculation de la Caraïbe (produits intérieurs bruts et éléments des balances des paiements), la recherche menée montre qu’hormis peut-être le cas à approfondir d’Antigua, aucune corrélation significative n’existe entre le nombre de navires immatriculés et les gains économiques dans les pays d’accueil. Ces résultats vont dans le sens des critiques de la libre immatriculation : cette activité ne présente pas, en soi, un gain pour les petites économies insulaires étudiées.
https://tel.archives-ouvertes.fr/tel-00697681

Droits : info:eu-repo/semantics/OpenAccess
NNT : 2012AGUY0508
tel-00697681
https://tel.archives-ouvertes.fr/tel-00697681
https://tel.archives-ouvertes.fr/tel-00697681/document
https://tel.archives-ouvertes.fr/tel-00697681/file/12angelleli.pdf