Éditeur(s) : HAL CCSD Université des Antilles
Résumé : International audience
ISSN: 1779-0980

hal-01624738
https://hal.archives-ouvertes.fr/hal-01624738
DOI : 10.4000/etudescaribeennes.3383

Éditeur(s) : Londres : P. S. King and Son
Siècle(s) traité(s) : 19
Provenance : Université Caen Normandie. Service commun de la documentation
Permalien : http://www.manioc.org/patrimon/CAE19037
CAE19037

Éditeur(s) : HAL CCSD Lippincott, Williams & Wilkins
Résumé : International audience
OBJECTIVE: In immunocompromised patients, alternative schedules more immunogenic than the standard influenza vaccine regimen are necessary to enhance and prolong vaccine efficacy. We previously reported that the AS03A-adjuvanted 2009 A/H1N1v vaccine yielded a higher short-term immune response than the nonadjuvanted one in HIV-1-infected adults. This study reports the long-term persistence of the immune response. DESIGN AND METHODS: In a prospective, multicenter, randomized, patient-blinded trial, two doses of AS03A-adjuvanted H1N1v vaccine containing 3.75 μg haemagglutinin (n = 155; group A) or nonadjuvanted H1N1v vaccine containing 15 μg haemagglutinin (n = 151; group B), were administered 21 days apart. Haemagglutination inhibition and neutralizing antibodies were assessed 6 and 12 months after vaccination. RESULTS: In group A and B, the seroprotection rates were 83.7 and 59.4% at month 6, and 70.4 and 49.3 at month 12, respectively. In a multivariate analysis, persistence of seroprotection 12 months after vaccination was negatively associated with current smoking (odds ratio = 0.6, P = 0.03) and positively related with the AS03A-adjuvanted H1N1v vaccine (odds ratio = 2.7, P = 0.0002). CONCLUSION: In HIV-1-infected adults, two doses of adjuvanted influenza vaccine induce long-term persistence of immune response up to 1 year after vaccination.
ISSN: 0269-9370

hal-00875148
https://hal.archives-ouvertes.fr/hal-00875148
DOI : 10.1097/QAD.0b013e328359f27a
PUBMED : 23018437

Éditeur(s) : HAL CCSD
Résumé : International audience
Le tourisme à la ferme fait l'objet d'un intérêt croissant, tant de la part des médias que des élus, en cette période de crise que traversent de nombreuses zones rurales où dominaient traditionnellement les activités et les emplois agricoles.En effet, en raison de l'affirmation du secteur touristique dans l'économie et des nouvelles attentes des clientèles urbaines en quête de verdure, d'authenticité et de qualité, il semble qu'il y ait une "opportunité à saisir" pour les agriculteurs confrontés à une remise en cause de leur mode de production, de leur mode de vie. Après les décennies de travail vouées à l'intensification et à la spécialisation, les difficultés actuelles imposent à nombre d'agriculteurs des stratégies de diversification susceptibles d'apporter de nouvelles sources de revenus...
Géo-Centre-Ouest, Poitiers

hal-01405862
https://hal.univ-antilles.fr/hal-01405862
https://hal.univ-antilles.fr/hal-01405862/document
https://hal.univ-antilles.fr/hal-01405862/file/1997%20L%27agrotourisme%20en%20Poitou-Charentes.pdf

Éditeur(s) : HAL CCSD
Résumé : International audience
Background: The aim of this study was to identify the predictive factors of HIV disclosure to the sex partner in HIV pregnant women in Cayenne (French Guiana). Methods: A case control study was conducted including all deliveries in Cayenne from 2003 to 2010. For each case, a standardized questionnaire including epidemiological, clinical, and biological data was administered. Thirty-four women in the first group and 95 in the control group were included in the study. Results: The logistic regression showed that the variables that independently predicted HIV disclosure to the sex partner were the existence of a profession (OR=5.62, IC95% =1.3-24.26, p=0.021), disclosure to the doctor (OR=12.65, IC95% =2.87-55.8, p<0.001), the negative representations of HIV (OR=5.99, IC95% =1.17-30.69, p=0.032). The partner's HIV status was also linked to the outcome (OR=0.01, IC95% =0.001-0.07, p<0.001). Conclusion: These predictive factors should be considered in positive prevention programs and prevention of mother to child transmission.
Epidemiol

inserm-00915113
http://www.hal.inserm.fr/inserm-00915113
http://www.hal.inserm.fr/inserm-00915113/document
http://www.hal.inserm.fr/inserm-00915113/file/2012_Elenga_-_Predictive_Factorssur HIV_Status_Disclosure_to_Sex_Partner_in_Pregnant_women_in_cayenne_french_guiana.pdf
DOI : 10.4172/2161-1165.1000116

Éditeur(s) : HAL CCSD Oxford University Press
Résumé : International audience
The BioMart Community Portal (www.biomart.org) is a community-driven effort to provide a unified interface to biomedical databases that are distributed worldwide. The portal provides access to numerous database projects supported by 30 scientific organizations. It includes over 800 different biological datasets spanning genomics, proteomics, model organisms, cancer data, ontology information and more. All resources available through the portal are independently administered and funded by their host organizations. The BioMart data federation technology provides a unified interface to all the available data. The latest version of the portal comes with many new databases that have been created by our ever-growing community. It also comes with better support and extensibility for data analysis and visualization tools. A new addition to our toolbox, the enrichment analysis tool is now accessible through graphical and web service interface. The BioMart community portal averages over one million requests per day. Building on this level of service and the wealth of information that has become available, the BioMart Community Portal has introduced a new, more scalable and cheaper alternative to the large data stores maintained by specialized organizations.
ISSN: 0305-1048

hal-01146849
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01146849
DOI : 10.1093/nar/gkv350
PUBMED : 25897122

Éditeur(s) : HAL CCSD Human Kinetics
Résumé : International audience
OBJECTIVE: The aim was to examine the relationship between physical activity pattern and dietary profile. Although some clustering of the variables related to these major determinants of cardiovascular risk has been demonstrated, they have not been extensively studied together. PARTICIPANTS, DESIGN, AND SETTING: Two hundred two female university students from the main Guadeloupe (French West Indies) campus participated. They self-administered a validated Food Frequency Questionnaire and the 1-yr recall Modifiable Activity Questionnaire. Principal-component analysis was performed on the scores and the variables related to the physical activity pattern and dietary profile. RESULTS: A model including 10 variables explained 84.9% of the total variance. The physical activity pattern was not associated with the dietary profile, apart from fruit intake. The physical activity level was homogeneously low (median 1.58, first and last quartile cutoffs 1.54 and 1.66, respectively). There was no correlation between the physical activity level and the Food Frequency Questionnaire score (r=-.005). CONCLUSIONS: The absence of a strong relationship between the food and physical activity profiles is interpreted as a possible reflection of a dysregulation of the quality of food intake in this population with a sedentary lifestyle.
ISSN: 1526-484X

hal-00748203
https://hal.archives-ouvertes.fr/hal-00748203
DOI : 10.1123/ijsnem.20.5.401
PUBMED : 20975108

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Projections of climate change impacts on coral reefs produced at the coarse resolution (~1°) of Global Climate Models (GCMs) have informed debate but have not helped target local management actions. Here, projections of the onset of annual coral bleaching conditions in the Caribbean under Representative Concentration Pathway (RCP) 8.5 are produced using an ensemble of 33 Coupled Model Intercomparison Project phase-5 models and via dynamical and statistical downscaling. A high-resolution (~11 km) regional ocean model (MOM4.1) is used for the dynamical downscaling. For statistical downscaling, sea surface temperature (SST) means and annual cycles in all the GCMs are replaced with observed data from the ~4-km NOAA Pathfinder SST dataset. Spatial patterns in all three projections are broadly similar ; the average year for the onset of annual severe bleaching is 2040–2043 for all projections. However, downscaled projections show many locations where the onset of annual severe bleaching (ASB) varies 10 or more years within a single GCM grid cell. Managers in locations where this applies (e.g., Florida, Turks and Caicos, Puerto Rico, and the Domini-can Republic, among others) can identify locations that represent relative albeit temporary refugia. Both downscaled projections are different for the Bahamas compared to the GCM projections. The dynamically downscaled projections suggest an earlier onset of ASB linked to projected changes in regional currents, a feature not resolved in GCMs. This result demonstrates the value of dynamical downscaling for this application and means statistically downscaled projections have to be interpreted with caution. However, aside from west of Andros Island, the projections for the two types of downscaling are mostly aligned; projected onset of ASB is within AE10 years for 72% of the reef locations.
ISSN: 1354-1013

Droits : http://creativecommons.org/licenses/by-nc/
hal-01223492
https://hal-univ-perp.archives-ouvertes.fr/hal-01223492
https://hal-univ-perp.archives-ouvertes.fr/hal-01223492/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01223492/file/Hooidonk_et_al-2015-Global_Change_Biology.pdf
DOI : 10.1111/gcb.12901

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
A temporary network of 10 broad-band seismic stations has been installed in French Polynesia for the Polynesian Lithosphere and Upper Mantle Experiment (PLUME). All the seismic stations were installed either on volcanic islands or on atolls of the various archipelagos of French Polynesia in a manner which complements the geographic coverage provided by the regional permanent stations. The primary aim of PLUME is to image the upper mantle structures related to plate motion and hotspot activity. However, because of its proximity to all sites, the ocean is responsible for a high level of noise in the seismic data and we show that these data can also be used to analyse ocean wave activity. The power spectral density (PSD) analyses of the seismic data recorded in French Polynesia show clear peaks in the 0.05– 0.10 Hz band (periods between 10 and 20 s), which corresponds to swell frequencies. Clear peaks in this frequency band are also observed in infrasonic data recorded on Tahiti. Ground motion analysis shows that the swell-related seismic noise (SRSN) is linearly polarized in the horizontal plane and its amplitude decreases rapidly with the distance from the shore. The microseismic and the infrasonic 'noise' amplitudes show very similar variations from station to station and both are strongly correlated with the swell amplitudes predicted by the National Oceanic and Atmospheric Administration (NOAA), wind-forced, 'WaveWatch' models. The swell direction can be estimated from SRSN polarization analysis but this has to be done with care since, for some cases, the ground motions are strongly controlled by the islands' anisometric shapes and by swell refraction processes. We find cases, however, such as Tahiti or roughly circular Tuamotu atolls, where the azimuth of the swell is in good agreement with the seismic estimates. We, therefore, demonstrate that the SRSN and the infrasonic signal observed in French Polynesia can be used in such cases as a proxy for swell amplitude and azimuth. From the continuous analysis of the data recorded in 2003 at the permanent seismic station PPTL in Tahiti, transfer functions have been obtained. This could provide a way to quantify the swell activity during the last two decades and, therefore, assist in the investigation of climate changes.
ISSN: 0956-540X

hal-01388809
http://hal.univ-reunion.fr/hal-01388809
http://hal.univ-reunion.fr/hal-01388809/document
http://hal.univ-reunion.fr/hal-01388809/file/Barruol_swell_GJI2006.pdf
DOI : 10.1111/j.1365-246X.2006.02871.x

Éditeur(s) : HAL CCSD
Résumé : International audience
Un festival, lorsqu'il atteint une certaine ampleur devient un facteur important du développement local. Il impulse une dynamique nouvelle dans l'espace où il se déroule, entraînant de nombreuses conséquences tant sociales qu'économiques. Il ne laisse personne indifférent. On le vit, on le subit, on y participe. Toute la société est concernée par l'événement.Le festival de Confolens a acquis au fil des années une grande notoriété internationale même s'il se déroule dans une région rurale assez enclavée. Le Confolentais est une région très peu industrialisée qui souffre de déprise agricole. Le dépeuplement s'inscrit davantage dans le paysage à chaque recensement...
Géo-Centre-Ouest, Poitiers

hal-01405810
https://hal.univ-antilles.fr/hal-01405810
https://hal.univ-antilles.fr/hal-01405810/document
https://hal.univ-antilles.fr/hal-01405810/file/1994%20le%20festival%20de%20folklore%20de%20Confolens.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Diploid budding yeast undergoes rapid mitosis when it ferments glucose, and in the presence of a non-fermentable carbon source and the absence of a nitrogen source it triggers sporulation. Rich medium with acetate is a commonly used pre-sporulation medium, but our understanding of the molecular events underlying the acetate-driven transition from mitosis to meiosis is still incomplete. We identified 263 proteins for which mRNA and protein synthesis are linked or uncoupled in fermenting and respiring cells. Using motif predictions, interaction data and RNA profiling we find among them 28 likely targets for Ume6, a subunit of the conserved Rpd3/Sin3 histone deacetylase-complex regulating genes involved in metabolism, stress response and meiosis. Finally, we identify 14 genes for which both RNA and proteins are detected exclusively in respiring cells but not in fermenting cells in our sample set, including CSM4, SPR1, SPS4 and RIM4, which were thought to be meiosis-specific. Our work reveals intertwined transcriptional and post-transcriptional control mechanisms acting when a MATa/α strain responds to nutritional signals, and provides molecular clues how the carbon source primes yeast cells for entering meiosis. Our integrated genomics study provides insight into the interplay between the transcriptome and the proteome in diploid yeast cells undergoing vegetative growth in the presence of glucose (fermentation) or acetate (respiration). Furthermore, it reveals novel target genes involved in these processes for Ume6, the DNA binding subunit of the conserved histone deacetylase Rpd3 and the co-repressor Sin3. We have combined data from an RNA profiling experiment using tiling arrays that cover the entire yeast genome, and a large-scale protein detection analysis based on mass spectrometry in diploid MATa/α cells. This distinguishes our study from most others in the field-which investigate haploid yeast strains-because only diploid cells can undergo meiotic development in the simultaneous absence of a non-fermentable carbon source and nitrogen. Indeed, we report molecular clues how respiration of acetate might prime diploid cells for efficient spore formation, a phenomenon that is well known but poorly understood.
ISSN: 1874-3919

hal-01122122
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122122
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122122/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01122122/file/Integrated%20RNA-%20and%20protein%20profiling%20of%20fermentation.pdf
DOI : 10.1016/j.jprot.2015.01.015

Éditeur(s) : HAL CCSD Université des Antilles
Résumé : International audience
Islands were studied for a long time as simple peripheral territories, territories which flesh out the seamless continuation of continental logic, meaningless territories without the prism and perspective of metropolitan power. Through the field of the island studies, critical questions cross various island experiences and their context of development and their configurations; or otherwise study specific temporalities, connectivities and materialities, in the context of globalization. To study islands requires taking the measure of these territories, far from any monolithic vision, to analyze their space with regard to their social and political realities, to identify their economic clout and their context of development and the legacies of the history, in consideration of their geographical neighbourhood. It is a question of considering the exogenous logics which make the island and interrogate its internal dynamics.The subject of study is the island, "island" as object, the island in the management of its space, the definition of its territorial project, the positioning of the island in its environmental perspective and the opportunities it enjoys and the strategies it deploys in the globalized economy. The wealth of scholarship of and about islands and island societies extends beyond the simple spatial frame of the island; ‘the Island’ can be understood as a synecdoche, a convenient, manageable and reasonable microcosm of the continent.
Les îles ont longtemps été étudiées comme de simples lieux périphériques, inscrits dans le prolongement de logiques continentales ; des espaces dépourvus de sens en dehors du prisme des puissances métropolitaines. A travers le champ des études insulaires, il s’agit désormais de croiser les différentes expériences insulaires, de poser les contextes de développement et d’étudier les configurations et les temporalités spécifiques des îles. Étudier les îles nécessite de prendre la mesure de ces territoires -loin de toute vision monolithique-, d’analyser leur espace au regard des réalités sociale et politique, de cerner leur poids économique et leur contexte de développement, des héritages de l’histoire à la prise en compte de leur voisinage géographique. Il s’agit de prendre en considération les logiques exogènes qui font l’île et d’interroger les dynamiques internes.Le sujet d’étude est l’île, l’objet «île », l’île dans la gestion de son espace, la définition de son projet territorial, le positionnement de l’île dans son environnement respectif et les opportunités et stratégies dans l’économie mondialisée. La richesse des enseignements des territoires et des sociétés insulaires débordent le simple cadre spatial de l’île qui peut être entendue comme une synecdoque, un microcosme commode et raisonnable du continent.
ISSN: 1779-0980

Droits : http://creativecommons.org/licenses/by-nc/
hal-01368434
https://hal.univ-antilles.fr/hal-01368434
https://hal.univ-antilles.fr/hal-01368434/document
https://hal.univ-antilles.fr/hal-01368434/file/mondes-insulaires-espaces-temporalites-ressources.pdf
DOI : 10.4000/etudescaribeennes.7272

Éditeur(s) : HAL CCSD
Résumé : International audience
Biodiversité et Gestion des territoires
Schoelcher, Martinique

hal-01634304
https://hal.archives-ouvertes.fr/hal-01634304

Éditeur(s) : HAL CCSD Université des Antilles
Résumé : International audience
Ecotourism provides an original conceptual framework that enables approaches to development that are better able to provide a more equitable distribution of income, as well as better organized and thought through initiatives which are more likely to promote a holistic sustainable local development. With somewhat less negative impact than normal tourism, considerably less that mass tourism, ecotourism can encompass nature tourism, cultural tourism, scientific exploration, and even outdoor sports... A definition of ecotourism should take into account the following six points: 1/ nature and culture, 2/ the welfare of the host community, tourists acting responsibly, 3/ participation by the local community, 5 / sustainability , 6/ promotion of cultural exchanges.
L’écotourisme ouvre un cadre conceptuel original qui permet d’envisager des démarches renouvelées de développement à partir des revenus issus de consommations touristiques mieux réfléchies et organisées, susceptibles de soutenir des initiatives de développement local s’inscrivant dans un projet global de développement durable. Variante douce du tourisme, loin du tourisme de masse, le champ de l’écotourisme s’étend aux confins du tourisme de nature, du tourisme culturel et des pratiques scientifiques et sportives de plein air. Une définition de l’écotourisme peut être proposée à partir des six points suivants : 1/ nature et culture, 2/ le bien-être des sociétés hôtes, 3/ des touristes responsables, 4/ la participation des sociétés hôtes, 5/ la durabilité, 6/ l’art de la rencontre.
ISSN: 1779-0980

hal-01624739
https://hal.archives-ouvertes.fr/hal-01624739
DOI : 10.4000/etudescaribeennes.414

Éditeur(s) : HAL CCSD
Résumé : International audience
The tourist activity, by its international character and as a constantly expanding economic sector emerges as a means of obtaining international recognition being meanwhile an important economic sector of the national economy. In Romania case it appears as an "air breath" for an economic system in crisis and an extremely rolonged period of transition. By the dynamics, human and financial flow which it triggers, through the multiple forms which it covers, through the ability by which some thresholds (i.e. ideological or political) can impose an evolving path, tourism represents an economic sector for the countries in transition which can re-lauch or re-direct the subsequent evolution of a national economy. In ordeur to reach to these parameters a re-definition and a re-discovery of the real tourist potential is required in Romania case.
Condtions of the Foreign Tourism Developement in Central and Eastern Europe. Problems of the Development of Ecotourism with Special Emphasis on Mountain Areas

ISBN : 83-87196-28-2
hal-01412866
https://hal.univ-antilles.fr/hal-01412866
https://hal.univ-antilles.fr/hal-01412866/document
https://hal.univ-antilles.fr/hal-01412866/file/2002%20Alternatives%20for%20the%20development%20of%20tourism%20in%20Romania.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Background & Aims: The severity of liver diseases is exacerbated by the death of hepatocytes, which can be induced by the sensing of pathogen associated molecular patterns (PAMPs) derived from the gut microbiota. The molecular mechanisms regulating these cell death pathways are poorly documented. In this study, we investigated the role of the receptor interacting protein kinase 1 (RIPK1), a protein known to regulate cell fate decisions, in the death of hepatocytes using two in vivo models of PAMP-induced hepatitis. Methods: Hepatitis was induced in mice by independent injections of two different bacterial PAMPs: lipopolysaccharide (LPS) and unmethylated CpG oligodeoxynucleotide (CpG-DNA) motifs. The role of RIPK1 was evaluated by using mice specifically lacking RIPK1 in liver parenchymal cells (Ripk1(LPC-KO)). Administration of liposome-encapsulated clodronate served to investigate the role of Kupffer cells in the establishment of the disease. Etanercept, a tumor necrosis factor (TNF)-decoy receptor, was used to study the contribution of TNF-alpha during LPS-mediated liver injury. Results: Whereas RIPK1 deficiency in liver parenchymal cells did not trigger basal hepatolysis, it greatly sensitized hepatocytes to apoptosis and liver damage following a single injection of LPS or CpG-DNA. Importantly, hepatocyte death was prevented by previous macrophage depletion or by TNF inhibition. Conclusions: Our data highlight the pivotal function of RIPK1 in maintaining liver homeostasis in conditions of macrophage-induced TNF burst in response to PAMPs sensing. Lay summary: Excessive death of hepatocytes is a characteristic of liver injury. A new programmed cell death pathway has been described involving upstream death ligands such as TNF and downstream kinases such as RIPK1. Here, we show that in the presence of LPS liver induced hepatic injury was due to secretion of TNF by liver macrophages, and that RIPK1 acts as a powerful protector of hepatocyte death. This newly identified pathway in the liver may be helpful in the management of patients to predict their risk of developing acute liver failure. (C) 2017 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
ISSN: 0168-8278

hal-01532060
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01532060
DOI : 10.1016/j.jhep.2017.01.005
PUBMED : 28088582

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
Increasingly frequent severe coral bleaching is among the greatest threats to coral reefs posed by climate change. Global climate models (GCMs) project great spatial variation in the timing of annual severe bleaching (ASB) conditions; a point at which reefs are certain to change and recovery will be limited. However, previous model-resolution projections (~1 × 1°) are too coarse to inform conservation planning. To meet the need for higher-resolution projections, we generated statistically downscaled projections (4-km resolution) for all coral reefs; these projections reveal high local-scale variation in ASB. Timing of ASB varies >10 years in 71 of the 87 countries and territories with >500 km 2 of reef area. Emissions scenario RCP4.5 represents lower emissions mid-century than will eventuate if pledges made following the 2015 Paris Climate Change Conference (COP21) become reality. These pledges do little to provide reefs with more time to adapt and acclimate prior to severe bleaching conditions occurring annually. RCP4.5 adds 11 years to the global average ASB timing when compared to RCP8.5; however, >75% of reefs still experience ASB before 2070 under RCP4.5. Coral reef futures clearly vary greatly among and within countries, indicating the projections warrant consideration in most reef areas during conservation and management planning.
ISSN: 2045-2322

hal-01441969
https://hal-univ-perp.archives-ouvertes.fr/hal-01441969
https://hal-univ-perp.archives-ouvertes.fr/hal-01441969/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01441969/file/local%20scale.pdf
DOI : 10.1038/srep39666

Éditeur(s) : HAL CCSD L'Harmattan
https://hal-agroparistech.archives-ouvertes.fr/hal-01543079

hal-01543079
https://hal-agroparistech.archives-ouvertes.fr/hal-01543079

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Analysis of microbial biodiversity is hampered by a lack of reference genomes from most bacteria, viruses, and algae. This necessitates either the cultivation of a restricted number of species for standard sequencing projects or the analysis of highly complex environmental DNA metagenome data. Single-cell genomics (SCG) offers a solution to this problem by constraining the studied DNA sample to an individual cell and its associated symbionts, prey, and pathogens. We used SCG to study marine heterotrophic amoebae related to Paulinella ovalis (A. Wulff) P.W. Johnson, P.E. Hargraves & J.M. Sieburth (Rhizaria). The genus Paulinella is best known for its photosynthetic members such as P.chromatophora Lauterborn that is the only case of plastid primary endosymbiosis known outside of algae and plants. Here, we studied the phagotrophic sister taxa of P.chromatophora that are related to P.ovalis and found one SCG assembly to contain -cyanobacterial DNA. These cyanobacterial contigs are presumably derived from prey. We also uncovered an associated cyanophage lineage (provisionally named phage PoL_MC2). Phylogenomic analysis of the fragmented genome assembly suggested a minimum genome size of 200Kbp for phage PoL_MC2 that encodes 179 proteins and is most closely related to Synechococcus phage S-SM2. For this phage, gene network analysis demonstrates a highly modular genome structure typical of other cyanophages. Our work demonstrates that SCG is a powerful approach for discovering algal and protist biodiversity and for elucidating biotic interactions in natural samples.
ISSN: 0022-3646

hal-01544797
https://hal.archives-ouvertes.fr/hal-01544797
DOI : 10.1111/jpy.12028

Éditeur(s) : HAL CCSD L'Harmattan
https://hal-agroparistech.archives-ouvertes.fr/hal-01543077

hal-01543077
https://hal-agroparistech.archives-ouvertes.fr/hal-01543077