Éditeur(s) : IRD : Institut de Recherche pour le Développement Université des Antilles et de la Guyane IRD : Institut de Recherche pour le Développement Université des Antilles et de la Guyane
Extrait de : "Projet CARIBSAT, système caribéen d'information environnementale" : conférence, le 21 mars 2013. Université des Antilles et de la Guyane
Résumé : L'intervention débute par la présentation de l'organisation de l'Espace Sud. Cet EPCI a des compétences qui couvrent l’aménagement du territoire, l'urbanisme et les transports, lesquelles s'appliquent au sud de la Martinique. L'optimisation de ces missions a conduit à la mise en place d'un outil cartographique, spécifiquement un Système d'information géographique. Ce SIG, lancé par un contrat de mandature 2008-2013, doit apporter des outils approfondis d'analyse, de gestion et de diagnostic. Ils concerneront entre autres la planification urbaine, le zonage, le PLU, les équipements publics ou l'immobilier, accessibles autant par les décideurs que par les particuliers. L'intégration au projet CARIBSAT a servi à l'application de techniques de télédétection utiles à la construction du SIG, par une approche spatiale couplant l'analyse des phénomènes naturels et des actions anthropiques.
L'intervention débute par la présentation de l'organisation de l'Espace Sud. Cet EPCI a des compétences qui couvrent l’aménagement du territoire, l'urbanisme et les transports, lesquelles s'appliquent au sud de la Martinique. L'optimisation de ces missions a conduit à la mise en place d'un outil cartographique, spécifiquement un Système d'information géographique. Ce SIG, lancé par un contrat de mandature 2008-2013, doit apporter des outils approfondis d'analyse, de gestion et de diagnostic. Ils concerneront entre autres la planification urbaine, le zonage, le PLU, les équipements publics ou l'immobilier, accessibles autant par les décideurs que par les particuliers. L'intégration au projet CARIBSAT a servi à l'application de techniques de télédétection utiles à la construction du SIG, par une approche spatiale couplant l'analyse des phénomènes naturels et des actions anthropiques.
Siècle(s) traité(s) : 21
Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V13086
V13086
V13086
V13086

Éditeur(s) : CRPLC : Centre de Recherche sur les Pouvoirs Locaux dans la Caraïbe CCEE : Conseil de la Culture, de l'Education et de l'Environnement
Extrait de : "La collectivité territoriale de Martinique : enjeux, débats et perspectives" : séminaire, le 24 octobre 2015. Université des Antilles
Description : La mise en place de la CTM nécessite une nouvelle approche des politiques publiques territoriales. En effet, en procédant à la fusion des compétences de la région et de celles du département, elle impose de penser globalement et de manière transversale l'action publique locale. Un exemple mérite d'être signalé : là où, dans l'Hexagone, les départements sont en charge des collèges, les régions des lycées et des transports scolaires, à la Martinique, une seule entité, la CTM, exerce l'ensemble de ces compétences. D'où la possibilité de dégager désormais une vision globale du système éducatif.
Siècle(s) traité(s) : 21
Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V15421
V15421

Éditeur(s) : American Geophysical Union
Résumé : As part of the French CLIPPER project, an eddy permitting model of the Atlantic circulation has been run for 22 years. The domain has open boundaries at Drake passage and at 30 degreesE, from Africa to Antarctica. The simulated mean circulation, as well as the eddy activity, is satisfactory for a 1/3 degrees model resolution, and the meridional heat transport at 30 degreesS is within the range estimated from observations. We use the "mixed" open boundary algorithm of Barnier et al. [1998], which has both a radiation condition and a relaxation to climatology. The climatological boundary forcing strongly constrains the solution in the whole domain. The model heat balance adjusts through the surface (heat flux retroaction term) more than the open boundaries. The radiation phase velocities calculated within the algorithm are analyzed. This shows, quite surprisingly, that both the eastern and western boundaries have a similar behavior, regardless of the preferred directions for advection (mainly eastward) and wave propagation (mainly westward). Our results confirm that open boundary algorithms behave differently according to the dynamics of the region considered. The passive boundary condition that Penduff et al. [2000] applied successfully in the north eastern Atlantic does not work in the present South Atlantic model. We emphasize the need for a careful prescription of the climatology at the open boundary, for which a new approach based on synoptic sections is implemented.
Journal of Geophysical Union - Research C - Oceans (0148-0227) (American Geophysical Union), 2001-10 , Vol. 106 , N. C10 , P. 22115-22129

Droits : 2001 American Geophysical Union
http://archimer.ifremer.fr/doc/2001/publication-454.pdf
DOI:10.1029/2000JC000376
http://archimer.ifremer.fr/doc/00000/454/

Éditeur(s) : HAL CCSD IOS Press
Résumé : International audience
The hematocrit-to-viscosity ratio (HVR) has been widely used has an estimate of red blood cell (RBC) oxygen transport effectiveness into the microvasculature or as an oxygen delivery index. However, no study investigated the possibility of HVR to truly reflect RBC oxygen transport effectiveness or to be an oxygen delivery index. We measured blood viscosity at high shear rate (225 s-1), hematocrit, HVR, as well as the microvascular oxyhemoglobin saturation (TOI; tissue oxygen index) by spatial resolved near-infrared spectroscopy (NIRS) at cerebral and muscle levels in three population known to have various degrees of hemorheological abnormalities: healthy subjects (AA), patients with sickle cell SC disease (SC) characterized by moderate anemia and patients with sickle cell anemia (SS) marked by severe anemia. At both the cerebral and muscle level, HVR was positively correlated with TOI (r = 0.28; p = 0.03 and r = 0.38; p = 0.003, at the cerebral and muscle level, respectively). These findings suggest that HVR probably play a key role in blood flow and hemodynamic regulation in the microvasculature, hence modulating the amount of oxygen available for tissues. Nevertheless, the strengths of the associations are weak (R2 < 0.50), suggesting that other determinants modulate microvascular blood flow and oxygenation, such as vascular geometry and vasomotor reserve.
ISSN: 1386-0291

inserm-01081701
http://www.hal.inserm.fr/inserm-01081701
http://www.hal.inserm.fr/inserm-01081701/document
http://www.hal.inserm.fr/inserm-01081701/file/2013%2C%20Waltz%20-%20Is%20there%20a%20relationship%20between%20the%20hematocrit-to-viscosity%20ratio%20and%20microvascular%20oxygenation%20in%20brain%20and%20muscle.pdf
PUBMED : 23719422

Éditeur(s) : CRILLASH : Centre de Recherches Interdisciplinaires en Lettres, Langues, Arts et Sciences Humaines
Extrait de : "Patrimonialisation et développement dans la Caraïbe et les Amériques" : colloque international, du 2 au 4 mars 2011. Université des Antilles et de la Guyane
Description : Présentation d'un projet d'extension portuaire de la ville de Bastia, principal port méditerranéen de transport de passagers dont la taille des infrastructures est actuellement insuffisante. Pourtant, malgré la définition d'un territoire par les acteurs qui le compose, le patrimoine n'a pas été au centre de cet aménagement. De plus, le montant élevé des travaux, a imposé un débat public avec l'ensemble des citoyens. Seulement, bien que les plans soient actés par la collectivité locale, des collectifs ont jugés ces débats de mascarade démocratique et ont décidé de s'opposer au projet. Quel modèle de développement emprunter ? L'extension du port est-elle profitable pour les populations locales ? Les autorités locales sont-elles capables de prendre en compte les acteurs locaux ?...
Siècle(s) traité(s) : 21
Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V12046
V12046

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : For Norwegians the name of our country is based on a route - "the way to the North" - and this was not a built route but using of the coast-line itself. As long as the boats and ships were the main means of travel this coastal way - "Nor-way" - was the main communication basis for most people, and for transport of goods. But even in the interior of the country, water, namely rivers and lakes were the main structures for communication. The lakes were most efficient for transport during the cold winters, by sledges on the frozen surfaces.When new means of transport took over most of the traffic, however, sea, lakes and rivers in many ways became obstacles instead of means of communication (?). This gave the government and others new challenges. In the sailing period up to the end of the eighteen hundreds, boats and harbors were the investment focus and sailors were recruited in every community from the age of 15. This meant that in a remote area at the Arctic Circle there were plenty of people who have been sailing around most of the work and could easily be hosts of visitors.This paper is mostly focusing on "how to market and develop these beautiful coastal areas to travelers using either their own cars, bikes, boats or collective transport". What types of geographical units are suited for marketing and developing such areas and how might local producers of accommodation, food & beverages, crafts, activities and arts be included in such organizations. The main focus will be on the work of organization "Kystriksvegen Reiseliv AS" that have been working with these challenges for closed to two decades. What have their successes and obstacles been and how have they been able to operate a sustainable business on a long coastal route with many car ferries, small islands, fjords and mountains and more than twenty municipalities.
Pour les Norvégiens, le nom de notre pays est basé sur un itinéraire - «le chemin vers le Nord» - et ce n'était pas une route construite, mais qui repose sur la ligne de côte elle-même. Tant que les bateaux et les navires étaient le principal moyen de déplacement de cette façon côtière – "Nor-way" - était la base principale de communication pour la plupart des gens et pour le transport de marchandises, et même à l'intérieur du pays, l'eau, à savoir les rivières et les lacs étaient les principales structures de communication. Les lacs sont les plus efficaces pour le transport pendant les hivers froids, par traîneaux sur les surfaces gelées.Avec l’arrivée des nouveaux moyens de transport, la mer, les lacs et les rivières à bien des égards, sont devenus obstacles (?). Cela a donné de nouveaux défis au gouvernement. A l’époque de la voile jusqu'à la fin des dix-huit centaines, des bateaux et des ports ont été l'objet d'investissements et les marins ont été recrutés dans toutes les collectivités dès l’âge de 15 ans. Cela signifie que dans une région éloignée dans le cercle arctique, il y avait beaucoup de gens qui étaient navigateurs et pouvaient facilement être les hôtes de visiteurs.Ce document est principalement axé sur «la façon de commercialiser et de développer ces belles régions côtières de voyageurs qui utilisent soit leurs propres voitures, motos, bateaux ou de transports collectifs». Quels types d'unités géographiques sont adaptés pour la commercialisation et le développement de ces régions ? Comment les producteurs locaux d'hébergement, de nourriture et de boissons, d’artisanat, les activités et les arts sont inclus dans ces organisations ? L'accent principal sera mis sur le travail de l’organisation "Reiseliv AS Kystriksvegen" qui a travaillé sur ces défis de fermeture depuis deux décennies. Quelles ont été leurs réussites et obstacles, et comment ont-ils pu exploiter une entreprise durable sur une longue route côtière avec des car-ferries, de nombreuses petites îles, des fjords et des montagnes et plus d’une vingtaine de municipalités.
Norvège

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5286
http://journals.openedition.org/etudescaribeennes/5286

Résumé : The purpose of this book is to value the economic significance of marine-related activities in France. Each industrial, or public non-commercial, sector is characterized by key figures relating to annual turnover, value added, employment and budget. These figures are accompanied with qualitative information on the recent development, current situation and future perspectives of the sector in terms of markets, employment and technological progress. Public and private R&D is also allowed for. Given the diversity of marine-related activities, this information aims at enabling the reader to assess their importance from a comparative angle. From the sector-based approach it is possible to draw certain conclusions. Notably, commercial activities contributed over 1,3% of the GDP in 1995, such ratio having to be seen as a minimum estimate, worked out on the basis of available data. Seaside-related tourism is by far the most important industry. Most activities experienced a decrease in employment in the first half of the '90s. The estimated annual amount spent on R&D was over FFr 4,5 billion in the recent past period 1995-1996.
Le présent ouvrage a pour but d'évaluer l'importance économique des activités liées à la mer en France. Chaque secteur - industriel marchand, public non marchand - est caractérisé par des chiffres clés portant sur le chiffre d'affaires annuel, la valeur ajoutée, l'emploi, le budget. Ces indicateurs sont accompagnés d'informations qualitatives sur l'évolution récente, la situation actuelle et les perspectives du secteur : marchés, emplois, progrès technique. La R&D publique et privée est également prise en compte. Compte tenu de la diversité des activités liées à la mer, ces informations visent à permettre au lecteur d'en apprécier l'importance sous un angle comparatif. L'approche sectorielle permet de tirer certaines conclusions. Notamment, les activités marchandes ont contribué à plus de 1,3 % du PIB en 1995, un tel ratio devant être compris comme un minimum, calculé à partir des données disponibles. Le tourisme littoral est, de loin, l'activité la plus importante. Dans la plupart des branches, l'emploi baisse dans la première moitié des années 1990. Les dépenses annuelles de R&D sont estimées à plus de 4,5 milliards de francs dans la période récente 1995-1996.

Droits : 1997 Ifremer
http://archimer.ifremer.fr/doc/2001/rapport-1347.pdf
http://archimer.ifremer.fr/doc/00000/1347/

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
Ro 31-8220 is a potent protein kinase C (PKC) inhibitor belonging to the chemical class of bisindolylmaleimides (BIMs). Various PKC-independent effects of Ro 31-8220 have however been demonstrated, including inhibition of the ATP-binding cassette drug transporter breast cancer resistance protein. In the present study, we reported that the BIM also blocks activity of the solute carrier organic cation transporter (OCT) 1, involved in uptake of marketed drugs in the liver, in a PKC-independent manner. Ro 31-8220, in contrast to other pan-PKC inhibitors such as staurosporine and chelerythrine, was thus shown to cis-inhibit uptake of the reference OCT1 substrate tetraethylammonium in OCT1-transfected HEK293 cells in a concentration-dependent manner (IC50 = 0.18 μM) and without altering membrane expression of OCT1. This blockage of OCT1 was also observed in human hepatic HepaRG cells that constitutionally express OCT1. It likely occurred through a mixed mechanism of inhibition. Ro 31-8220 additionally trans-inhibited TEA uptake in OCT1-transfected HEK293 cells, which likely discards a transport of Ro 31-8220 by OCT1. Besides Ro 31-8220, 7 additional BIMs, including the PKC inhibitor LY 333531, inhibited OCT1 activity, whereas 4 other BIMs were without effect. In silico analysis of structure-activity relationships next revealed that various molecular descriptors, especially 3D-WHIM descriptors related to total size, correspond to key physico-chemical parameters for inhibition of OCT1 activity by BIMs. In addition to activity of OCT1, Ro 31-8220 inhibited those of other organic cation transporters such as multidrug and toxin extrusion protein (MATE) 1 and MATE2-K, whereas, by contrast, it stimulated that of OCT2. Taken together, these data extend the nature of cellular off-targets of the BIM Ro 31-8220 to OCT1 and other organic cation transporters, which has likely to be kept in mind when using Ro 31-8220 and other BIMs as PKC inhibitors in experimental or clinical studies
ISSN: 1932-6203

hal-01255837
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01255837
DOI : 10.1371/journal.pone.0144667
PUBMED : 26657401
PUBMEDCENTRAL : PMC4675551

Éditeur(s) : HAL CCSD Taylor & Francis
Résumé : International audience
Introduction: Drug transporters are now recognized as major players involved in pharmacokinetics and toxicology. Methods for assessing their activity are important to consider, particularly owing to regulatory requirements with respect to inhibition of drug transporter activity and prediction of drug–drug interactions. In this context, the use of fluorescent-dye-based transport assays is likely to deserve attention.Areas covered: This review provides an overview of the nature of fluorescent dye substrates for ATP-binding cassette and solute carrier drug transporters. Their use for investigating drug transporter activity in cultured cells and clinical hematological samples, drug transporter inhibition, drug transporter imaging and drug transport at the organ level are summarized.Expert opinion: A wide range of fluorescent dyes is now available for use in various aspects of drug transporter studies. The use of these dyes for transporter analyses may, however, be hampered by classic pitfalls of fluorescence technology, such as quenching. Transporter-independent processes such as passive diffusion of dyes through plasma membrane or dye sequestration into subcellular compartments must also be considered, as well as the redundant handling by various distinct transporters of some fluorescent probes. Finally, standardization of dye-based transport assays remains an important on-going issue
ISSN: 1742-5255

hal-01162381
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01162381
DOI : 10.1517/17425255.2015.1053462
PUBMED : 26050735

Éditeur(s) : HAL CCSD Geological Society of America
Résumé : International audience
On the New Jersey shelf (offshore North America), the presence of pore water fresher than seawater is known from a series of boreholes completed during the 1970s and 1980s. To account for this fresh water, a fi rst hypothesis involves possible present-day active dynamic connections with onshore aquifers, while a second involves meteoritic and/or sub- ice-sheet waters during periods of lowered sea level. Expedition 313 drilled three boreholes on the middle shelf, offering a unique opportunity for the internal structure of the siliciclastic system to be accessed, at scales ranging from the depositional matrix to the continental margin. This enables the stratigraphic architecture to be correlated with the spatial distribution and salinity of saturating fl uids. Expedition 313 revealed both very low salinities (<3 g/L) at depths exceeding 400 m below the seafl oor and evidence for a multilayered reservoir organization, with freshand/ or brackish-water intervals alternating vertically with salty intervals. In this study we present a revised distribution of the salinity beneath the middle shelf. Our observations suggest that the processes controlling salinity are strongly infl uenced by lithology, porosity, and permeability. Saltier pore waters generally occur in coarse-grained intervals and fresher pore waters occur in fi ne-grained intervals. The transition from fresher to saltier intervals is often marked by cemented horizons that probably act as permeability barriers. In the lowermost parts of two holes, the salinity varies independently of lithology, suggesting different mechanisms and/or sources of salinity. We present an interpretation of the sedimentary facies distribution, derived from core, logs, and seismic profi le analyses, that is used to discuss the marginscale two-dimensional reservoir geometry and permeability distribution. These proposed geometries are of primary importance when considering the possible pathways and emplacement mechanisms for the fresh and salty water below the New Jersey shelf.
EISSN: 1553-040X

insu-00858241
https://hal-insu.archives-ouvertes.fr/insu-00858241
DOI : 10.1130/GES00855.1

Éditeur(s) : HAL CCSD Wiley-Blackwell Wiley
Résumé : International audience
Rhodamine 123 is a fluorescent cationic dye commonly used as a mitochondrial probe and known or suspected to be transported by certain drug membrane transporters. The present study was designed to characterize the putative interactions of rhodamine 123 with human organic cation transporter (OCT) 1 and OCT2. Intracellular uptake of the dye was demonstrated to be enhanced in both hOCT1- and hOCT2-overexpressing HEK293 cells when compared with control HEK293 cells. This increase of rhodamine 123 influxes was found to be a saturable carrier-mediated process, with low K(m) values (K(m) = 0.54 μm and K(m ) = 0.61 μm for transport of the dye in hOCT1- and hOCT2-positive HEK293 cells, respectively). Known inhibitors of hOCT1 and hOCT2 activities such as verapamil, amitriptyline, prazosin, and quinine were next demonstrated to decrease rhodamine 123 accumulation in hOCT1- and hOCT2-overexpressing HEK293 cells. In addition, the dye was found to inhibit hOCT1- and hOCT2-mediated uptake of tetraethylammonium (TEA), a model substrate for both hOCT1 and hOCT2; rhodamine 123 appeared nevertheless to be a more potent inhibitor of hOCT1-mediated TEA transport (IC(50) = 0.37 μm) than of that mediated by hOCT2 (IC(50 ) = 61.5 μm). Taken together, these data demonstrate that rhodamine 123 is a high-affinity substrate for both hOCT1 and hOCT2. This dye may be therefore useful for fluorimetrically investigating cellular hOCT1 or hOCT2 activity, knowing, however, that other factors potentially contributing to cellular accumulation of rhodamine 123, including mitochondrial membrane potential or expression of the efflux transporter P-glycoprotein, have also to be considered.
ISSN: 0767-3981

inserm-00872840
http://www.hal.inserm.fr/inserm-00872840
DOI : 10.1111/j.1472-8206.2012.01071.x
PUBMED : 22913740

Éditeur(s) : Elsevier Sci Ltd
Résumé : Several marine geophysical data and piston-coring surveys acquired during the last decade allow one to better understand the close dynamic interactions between the sand-rich Orinoco turbidite system and the compressional structures of the Barbados prism. These interactions have been active since Eocene time as illustrated by the study of outcrops onshore Barbados Island. Because of strong morphologic and tectonic control in the east-Caribbean active margin, the present-day Orinoco turbiditic pattern system does not exhibit a classic fan geometry. The sea-floor geometry between the slope of the front of the Barbados prism and the slope of the South-American margin induces the convergence of the turbidite channels toward the abyssal plain, at the front of the accretionary prism. Also, whereas in most passive margins the turbidite systems are organized upstream to downstream as canyon, channel-levee and lobes, here, due to the tectonic control, the sedimentary system is organized upstream to downstream as channel-levee, canyons and channelized lobes. Indeed, at the edge of the Orinoco platform, the system has multiple sources with several distributaries and downstream the channel courses are complex with frequent convergences or divergences that are emphasized by the effects of the undulating seafloor tectonic morphologies associated with active thrust tectonics and mud volcanism. On top of the accretionary prism, turbidite sediments are filling transported piggy-back basins whose timing of sedimentation vs. deformation is complex. While erosion processes are almost absent on the highly subsiding Orinoco platform and in the upper part of the turbidite system, they develop mostly between 2000 and 4000 m of water depth, above the compressional structures of the Barbados prism (canyons up to 3 km wide and 300 m deep). In the abyssal plain, the main turbiditic channel develops toward the east and connects with the Vidal mid-Atlantic channel. The sediments transported in this channel are filling several elongated basins linked with fracture zones (notably the Barracuda Basin), and finally end their course in the Puerto-Rico trench, the deepest morphologic depression of the region. Piston-cores have demonstrated that turbidite sediments above the accretionary prism and in the abyssal plain are mostly coarse sandy deposits covered by recent pelagic planktonic-rich sediments, which corresponds to slower sand deposition during the post-glacial sea level rise. Numerical stratigraphic modelling suggests that during the last glacial event, the main depocentres were located above the tectonic prism and in the abyssal plain, at the front of the prism and that, during the Holocene eustatic rise, a large accommodation space formed on the shelf confining sedimentation mostly on the Orinoco deltaic platform and producing a starvation downstream in the turbidite system.
Marine And Petroleum Geology (0264-8172) (Elsevier Sci Ltd), 2015-06 , Vol. 64 , P. 76-103

Droits : 2015 Elsevier Ltd. All rights reserved.
http://archimer.ifremer.fr/doc/00252/36373/34913.pdf
DOI:10.1016/j.marpetgeo.2014.12.015
http://archimer.ifremer.fr/doc/00252/36373/

Éditeur(s) : Elsevier
Résumé : High-resolution sedimentological and micropaleontological studies of several deep-sea cores retrieved from the levees of the Celtic and Armorican turbidite systems (Bay of Biscay - North Atlantic Ocean) allow the detection of the major oscillations of the British-Irish Ice Sheet (BIIS) and 'Fleuve Manche' palaeoriver discharges over the last 30,000 years, which were mainly triggered by climate changes. Between 30 and 20 cal ka, the turbiditic activity on the Celtic-Annorican margin was weak, contrasting with previous stratigraphic models which predicted a substantial increase of sediment supply during low sea-level stands. This low turbidite deposit frequency was most likely the result of a weak activity of the 'Fleuve Manche' palaeoriver and/or of a reduced seaward transfer of sediments from the shelf to the margin. However, two episodes of turbiditic activity increase were detected in the Celtic-Armorican margin, during Heinrich events (HE) 3 and 2. This strengthening of the turbiditic activity was triggered by the meltwater releases from European ice sheets and glaciers favouring the seaward transfer of subglacial material, at least via 'Fleuve Manche' palaeoriver. At around 20 cal ka, a significant increase of turbidite deposit frequency occurred as a response to the onset of the last deglaciation. The retreat of the European ice sheets and glaciers induced a substantial increase of the 'Fleuve Manche' palaeoriver discharges and seaward transfer of continentally-derived material into the Armorican turbidite system. The intensification of the turbiditic activity on the Celtic system was directly sustained by the widespread transport of subglacial sediments from the British-Irish Ice Sheet (BIIS) to the Celtic Sea via the Irish Sea Basin. A sudden reduction of turbiditic activity in the Armorican system, between ca. 19 and 18.3 cal ka, could have been triggered by the first well known abrupt sea-level rise ('meltwater pulse', at around 19 cal ka) favouring the trapping of sediment in the 'Fleuve Manche' palaeoriver valleys and the decrease of the seaward transfer of continentally-derived material. The maximum of turbiditic activity strengthening in the Celtic-Armorican margin, between ca. 18.3 and 17 cal ka, was induced by the decay of European ice sheets and glaciers producing the most extreme episode of the 'Fleuve Manche' palaeoriver runoff and a great seaward transfer of subglacial material into the Bay of Biscay, Between ca. 17.5 and 16 cal ka, the turbiditic activity significantly decreased in both Celtic and Armorican turbidite systems in response to a global re-advance of glaciers and ice sheets in Europe. The last episode of ice sheet retreat, between ca. 16 and 14 cal ka, is well expressed in the Celtic system by a new increase of the turbiditic activity. The major episode of sea-level rise at around 14 cal ka ('Meltwater Pulse 1A'), precluding the seaward transfer of sediments, induced the end of turbiditic activity in both the Celtic and the Armorican system. Although two main phases of global sea-level rise seem to have had an effect on the Celtic-Armorican margin, this work proposes the BUS retreat and associated riverine discharges as the main trigger mechanisms of the turbiditic activity in this region during the last 30,000 years.
Marine Geology (0025-3227) (Elsevier), 2008 , Vol. 247 , N. 1-2 , P. 84-103

Droits : 2008 Elsevier B.V. All rights reserved
http://archimer.ifremer.fr/doc/2008/publication-3729.pdf
DOI:10.1016/j.margeo.2007.08.006
http://archimer.ifremer.fr/doc/00000/3729/

Résumé : The maritime economy includes the activities linked to the sea, namely: - Marine resource extraction: living resources and marine minerals, - Exploitation of marine space and of physical properties of marine waters (energy plants - using marine water as a heat sink, marine renewable energies, submarine cable laying, - maritime and coastal construction and public works, maritime transport, Navy), - Exploitation of seascapes (tourism, leisure, boating), - Resource processing (of living resources and oil & gas) - Manufacturing and service industries supplying the above exploitation activities: shipbuilding, ship repair and boat building and their suppliers, oil and gas services, financial services, - Public services: defence; State intervention at sea and public services to maritime activities and to seafarers; public and private activities contributing to the protection of marine and coastal environment; and public research. Since 1997, the French Marine Economic Data report, published by Ifremer, includes a set of key sectoral indicators used to value the economic significance of the French marine-related activities in terms of production and jobs, their role in the national economy, their weight in international competition and the importance of non-market public services. The analysis of the marine sectors is carried out mainly at national scale but regional indicators are also presented when they are available. The European dimension of the activities is also taken into account.

Droits : 2014 Ifremer
http://archimer.ifremer.fr/doc/00253/36455/34990.pdf
DOI:10.13155/36455
http://archimer.ifremer.fr/doc/00253/36455/

Éditeur(s) : HAL CCSD Elsevier
Résumé : Understanding chemical element mobility during high-pressure metamorphism is paramount to the knowledge of the transformations occurring during the course of eclogite-facies metamorphism. In particular, the role of deformation and fluid circulation appear essential. In order to better decipher this role, we investigated two eclogite-facies samples from the Lindas Nappe in the Bergen arcs (Norwegian Caledonides), which are related to a fluid/deformation metamorphic event. This study, based on detailed microtextural investigations, coupled with major and trace element analyses, either in situ EMPA and LA-ICP-MS or by conventional ICP-MS nebulisation on mineral fractions, illustrates the complexity of chemical reactions accompanying the eclogite- and amphibolite-facies metamorphism. A single eclogite-facies mineral species two eclogite-facies (i.e. phengite and epidote) depicts various chemical features depending on its textural location at thin-section scale. The correlation with the mineralogical reaction occurring in each textural site demonstrates that the compositional variations are inherited from the precursor minerals. Thus, the composition of eclogite-facies minerals is locally controlled by the composition of few hundred-micron domains. On the contrary, alteration phases of the amphibolite facies (symplectite and calcic amphibole) display clear enrichment in LILE, Pb, Sr and LREE compared to their precursor minerals (omphacite and garnet). This supports that the transport of elements at hand-sample scale was enhanced during the retrogression and elements were efficiently delocalised from one textural site to another. The contrasting behaviour of element mobility between peak eclogite-facies metamorphism and retrogression can be explained in terms of rate processes and fluid/deformation activity. During eclogitisation,deformation allows the formation of textural and mineralogical microdomains. Contemporaneously the fluid circulation favours the development of heterogeneities by transport of elements in excess towards areas protected from deformation where phengite-bearing quartz lenses crystallise. This, together with the very fast recrystallisation of eclogite-facies minerals, results in a heterogeneous redistribution of elements at sample scale and in a chemical disequilibrium between different microdomains of hundred-micron size. During retrogression in the amphibolite facies, coeval with long-term ductile deformation, the fluids act as an efficient vector to redistribute the elements from a given textural site to another and, thus, allow to reach, at hand-sample scale, a new chemical equilibrium between the different crystallising phases.
ISSN: 0024-4937

hal-00404602
https://hal.archives-ouvertes.fr/hal-00404602
DOI : 10.1016/j.lithos.2006.10.001

Éditeur(s) : HAL CCSD Société géologique de France
Résumé : U-Pb ages obtained from detrital zircon from terrigenous sediments are used to determine the sources. Present fluvial sand-bars of the Ogooue river yield age spectra of detrital zircons in agreement with Archean and Early Proterozoic Sources found in the drainage. The large proportion of Late Proterozoic zircons cannot be derived from primary erosion of the watershed basement rocks, since there is no formation of that age in the area. This later group of zircons is in good agreement with reworking of the aeolian Paleogene Bateke Sands, by regressive erosion in the upper reaches of the Ogooue river, as they contain a majority of Late Proterozoic age zircons. The sources of Late Proterozoic zircons in the Bateke Sand are very distant, and transported and reworked - at least in part - by aeolian processes. Our results, together with the widely distributed Paleogene sediments over continental Africa, suggests that Paleogene was it time of subdued erosion of the cratonic areas and extensive reworking, transport and deposition within continental Africa. In contrast, our results from the Ogooue river indicate active present incision of the cratonic area, erosion of the previous continental sediments, and export of the river bed-load to the continental margin. This temporal evolution of erosion-transport-deposition is correlated with the drastic climate change that occurred during the Cenozoic, leading to a more efficient mechanical erosion, and it correlates with the increase of terrigenous flux to the margin, observed during the Neogene.
EISSN: 1777-5817

hal-00411165
https://hal.archives-ouvertes.fr/hal-00411165
DOI : 10.2113/gssgfbull.179.1.29

Éditeur(s) : HAL CCSD Taylor & Francis
Résumé : International audience
The retroviral genome consists of an intron-containing transcript that has essential cytoplasmic functions in the infected cell. This viral transcript can escape splicing, circumvent the nuclear checkpoint mechanisms and be transported to the cytoplasm by hijacking the host machinery. Once in the cytoplasm, viral unspliced RNA acts as mRNA to be translated and as genomic RNA to be packaged into nascent viruses. The murine leukemia virus (MLV) is among the first retroviruses discovered and is classified as simple Retroviridae due to its minimal encoding capacity. The oncogenic and transduction abilities of MLV are extensively studied, whereas surprisingly the crucial step of its nuclear export has remained unsolved until 2014. Recent work has revealed the recruitment by MLV of the cellular NXF1/Tap-dependent pathway for export. Unconventionally, MLV uses of Tap to export both spliced and unspliced viral RNAs. Unlike other retroviruses, MLV does not harbor a unique RNA signal for export. Indeed, multiple sequences throughout the MLV genome appear to promote export of the unspliced MLV RNA. We review here the current understanding of the export mechanism and highlight the determinants that influence MLV export. As the molecular mechanism of MLV export is elucidated, we will gain insight into the contribution of the export pathway to the cytoplasmic fate of the viral RNA
ISSN: 1547-6286

hal-01217990
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01217990
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01217990/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01217990/file/Insights%20into%20the%20nuclear%20export%20of%20murine%20leukemia%20virus%20intron-containing%20RNA.pdf
DOI : 10.1080/15476286.2015.1065375

Éditeur(s) : HAL CCSD IOS Press
Résumé : International audience
The hematocrit-to-viscosity ratio (HVR) has been widely used has an estimate of red blood cell (RBC) oxygen transport effectiveness into the microvasculature or as an oxygen delivery index. However, no study investigated the possibility of HVR to truly reflect RBC oxygen transport effectiveness or to be an oxygen delivery index. We measured blood viscosity at high shear rate (225 s −1), hematocrit, HVR, as well as the microvascular oxyhemoglobin saturation (TOI; tissue oxygen index) by spatial resolved near-infrared spectroscopy (NIRS) at cerebral and muscle levels in three population known to have various degrees of hemorheological abnormalities: healthy subjects (AA), patients with sickle cell SC disease (SC) characterized by moderate anemia and patients with sickle cell anemia (SS) marked by severe anemia. At both the cerebral and muscle level, HVR was positively correlated with TOI (r = 0.28; p = 0.03 and r = 0.38; p = 0.003, at the cerebral and muscle level, respectively). These findings suggest that HVR probably play a key role in blood flow and hemodynamic regulation in the microvasculature, hence modulating the amount of oxygen available for tissues. Nevertheless, the strengths of the associations are weak (R 2 < 0.50), suggesting that other determinants modulate microvascular blood flow and oxygenation, such as vascular geometry and vasomotor reserve.
ISSN: 1386-0291

hal-01163460
https://hal.univ-antilles.fr/hal-01163460
DOI : 10.3233/CH-131742

Éditeur(s) : Elsevier
Résumé : A study of organic carbon mineralization from the Congo continental shelf to the abyssal plain through the Congo submarine channel and Angola Margin was undertaken using in situ measurements of sediment oxygen demand as a tracer of benthic carbon recycling. Two measurement techniques were coupled on a single autonomous platform: in situ benthic chambers and microelectrodes, which provided total and diffusive oxygen uptake as well as oxygen microdistributions in porewaters. In addition, sediment trap fluxes, sediment composition (Org-C, Tot-N, CaCO3, porosity) and radionuclide profiles provided measurements of, respectively input fluxes and burial rate of organic and inorganic compounds. The in situ results show that the oxygen consumption on this margin close to the Congo River is high with values of total oxygen uptake (TOU) of 4 +/- 0.6, 3.6 +/- 0.5 mmol m(-2) d(-1) at 1300 and 3100m depth, respectively, and between 1.9 +/- 0.3 and 2.4 +/- 0.2 mmol m(-2) d(-1) at 4000 m depth. Diffusive oxygen uptakes (DOU) were 2.8 +/- 1.1, 2.3 +/- 0.8, 0.8 +/- 0.3 and 1.2 +/- 0.1 mmol m(-2) d(-1), respectively at the same depths. The magnitude of the oxygen demands on the slope is correlated with water depth but is not correlated with the proximity of the submarine channel-levee system, which indicates that cross-slope transport processes are active over the entire margin. Comparison of the vertical flux of organic carbon with its mineralization and burial reveal that this lateral input is very important since the sum of recycling and burial in the sediments is 5-8 times larger than the vertical flux recorded in traps. Transfer of material from the Congo River occurs through turbidity currents channelled in the Congo valley, which are subsequently deposited in the Lobe zone in the Congo fan below 4800 m. Ship board measurements of oxygen profiles indicate large mineralization rates of organic carbon in this zone, which agrees with the high organic carbon content (3%) and the large sedimentation rate (19 mm y(-1)) found on this site. The Lobe region could receive as high as 19 mol C m(-2) y(-1), 1/3 being mineralized and 2/3 being buried and could constitute the largest depocenter of organic carbon in the South Atlantic.
Deep Sea Research Part II: Topical Studies in Oceanography (0967-0645) (Elsevier), 2009-11 , Vol. 56 , N. 23 , P. 2223-2238

Droits : 2009 Elsevier B.V. All rights reserved.
http://archimer.ifremer.fr/doc/2009/publication-7316.pdf
DOI:10.1016/j.dsr2.2009.04.005
http://archimer.ifremer.fr/doc/00000/7316/

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The Tso Morari serpentinites in the Ladakh area, northwest Himalaya, originated from the forearc mantle overlying the northward subducting Neo-Tethys lithosphere and the margin of the Indian continent. The serpentinites are characterized by high concentration of fluid-mobile elements (FME: As, Sb, B, Li, and U) compared to ophiolitic or abyssal serpentinites. The Pb isotopic compositions of serpentinites show influence of the subducted Indian continental lithosphere. Trace element concentrations of antigorite determined in situ with Laser Ablation High Resolution Inductively Coupled Mass Spectrometer (LA-HR-ICP-MS) show high contents of FME including Pb, in contrast to the spatially associated iron oxides. Rare earth elements (REE) and compatible elements, such as Sc and Co, remained immobile during the hydration, allowing the identification of the primary minerals (olivine or orthopyroxene) from which serpentine formed. Serpentinized olivine displays higher Sb and As concentrations (up to 1000 x PM) than serpentinized orthopyroxenes that are enriched in Pb, Cs and Li (2 to up to 10 x PM).;We propose that the observed FME distribution in two types of serpentine reflect the differential incorporation of FME during the downward movement of the serpentinite along the subduction plane. At temperature lower than 400 degrees C, at shallow depths, olivine is preferentially serpentinized and incorporates elements that are fluid soluble at low temperatures, such as Sb and As. Above 400 degrees C, orthopyroxene is hydrated and incorporates Pb, Cs, Li and possibly Ba. Boron and U are incorporated in both types of serpentine suggesting that they are released from slabs at temperatures around 300-400 degrees C. The serpentine acts as a sink for water, but also for FME and transports them to deeper and hotter levels in the mantle, down to the isotherm 600-650 degrees C where dehydration occurs.
ISSN: 0009-2541

hal-00475565
https://hal.archives-ouvertes.fr/hal-00475565
DOI : 10.1016/j.chemgeo.2009.10.002