Éditeur(s) : Université des Antilles et de la Guyane. Faculté des lettres et sciences humaine Association Ouacabou Conseil général de la Martinique Musée Départemental d'Archéologie Précolombienne et de la Préhistoire
Extrait de : 24e congrès international de l'Association internationale d'archéologie de la Caraïbe, du 24 au 29 juillet 2011. Université des Antilles et de la Guyane"
Description : Cette communication nous présente une étude sur la plantation de Betty's Hope à Antigua. Betty's Hope est une ancienne propriété sucrière qui a fonctionné entre 1651 et 1944. Quel impact environnemental provoque la culture du sucre à Antigua ? Comment fonctionnait cette plantation sucrière (hommes, matériels, machines)?
Siècle(s) traité(s) : 20
Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V12090
V12090

Éditeur(s) : Springer
Résumé : The transforming growth factor (TGF)-beta superfamily is a group of important growth factors involved in multiple processes such as differentiation, cell proliferation, apoptosis and cellular growth. In the Pacific oyster Crassostrea gigas, the oyster gonadal (og) TGF-beta gene was recently characterized through genome-wide expression profiling of oyster lines selected to be resistant or susceptible to summer mortality. Og TGF-beta appeared specifically expressed in the gonad to reach a maximum when gonads are fully mature, which singularly contrasts with the pleiotropic roles commonly ascribed to most TGF-beta family members. The function of og TGF-beta protein in oysters is unknown, and defining its role remains challenging. In this study, we develop a rapid bacterial production system to obtain recombinant og TGF-beta protein, and we demonstrate that og TGF-beta is processed by furin to a mature form of the protein. This mature form can be detected in vivo in the gonad. Functional inhibition of mature og TGF-beta in the gonad was conducted by inactivation of the protein using injection of antibodies. We show that inhibition of og TGF-beta function tends to reduce gonadic area. We conclude that mature og TGF-beta probably functions as an activator of germ cells development in oyster.
Marine Biotechnology (1436-2228) (Springer), 2011-10 , Vol. 13 , N. 5 , P. 971-980

Droits : Springer Science+Business Media, LLC 2011
http://archimer.ifremer.fr/doc/00042/15371/13438.pdf
DOI:10.1007/s10126-010-9361-4
http://archimer.ifremer.fr/doc/00042/15371/

Éditeur(s) : HAL CCSD American Society for Microbiology
Résumé : International audience
A rapid and specific high-performance liquid chromatography method with UV detection (HPLC-UV) for the simultaneous determination of 12 beta-lactam antibiotics (amoxicillin, cefepime, cefotaxime, ceftazidime, ceftriaxone, cloxacillin, imipenem, meropenem, oxacillin, penicillin G, piperacillin, and ticarcillin) in small samples of human plasma is described. Extraction consisted of protein precipitation by acetonitrile. An Atlantis T3 analytical column with a linear gradient of acetonitrile and a pH 2 phosphoric acid solution was used for separation. Wavelength photodiode array detection was set either at 210 nm, 230 nm, or 298 nm according to the compound. This method is accurate and reproducible (coefficient of variation [CV] < 8%), allowing quantification of beta-lactam plasma levels from 5 to 250 μg/ml without interference with other common drugs. This technique is easy to use in routine therapeutic drug monitoring of beta-lactam antibiotics.
ISSN: 0066-4804

hal-00875271
https://hal.archives-ouvertes.fr/hal-00875271
https://hal.archives-ouvertes.fr/hal-00875271/document
https://hal.archives-ouvertes.fr/hal-00875271/file/Simultaneous_Determination-accepted.pdf
PUBMED : 21788467

Éditeur(s) : Direction Générale des Travaux Publics Direction Générale des Travaux Publics ( Haiti )
Résumé : This collection of over 5,000 black and white photographs held by the National Archives of Haiti dates from 1918 to 1945. It contains images of public buildings before and after restoration, public works, monuments, and the visits of U.S. Presidents and other officials.
Haiti

Droits : All rights reserved by the National Archives of Haiti.
7667

Extrait de : L'Univers. Histoire et description de tous les peuples, de leurs religions, mœurs, coutumes, etc. (Planche 89)
Siècle(s) traité(s) : 19
Droits : Domaine public
Permalien : http://www.manioc.org/images/GAD110440005i1
GAD110440005i1

North America -- United States Virgin Islands
Caribbean
1970-2005

Résumé : Speaker: Ruben Berrocal, Secretary General of Panama's National Secretariat of Science and Technology (SENACYT)
Introduction: Betty Loiselle, Director of the Tropical Conservation and Development Program, UF

Droits : Copyright UF Center for Latin American Studies and individual presenters. Permission granted to University of Florida to digitize and display this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
http://ufdc.ufl.edu/AA00028387/00002

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
A man and woman standing in the middle of trees. Slide labeled Betty's land, Cutting brush with machete.
Bahamas -- North America -- Hope Town, Elbow Cay, Abaco

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
Sheet 19:2
http://ufdc.ufl.edu/AA00029564/00001

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
We use velocities from 65 continuous stations and 31 survey-mode GPS sites as well as kinematic modeling to investigate present day deformation along the Africa-Iberia plate boundary zone in the western Mediterranean region. The GPS velocity field shows southwestward motion of the central part of the Rif Mountains in northern Morocco with respect to Africa varying between 3.5 and 4.0 mm/yr, consistent with prior published results. Stations in the southwestern part of the Betic Mountains of southern Spain move west-southwest with respect to Eurasia (similar to 2-3 mm/yr). The western component of Betics motion is consistent with partial transfer of Nubia-Eurasia plate motion into the southern Betics. The southward component of Betics motion with respect to Iberia is kinematically consistent with south to southwest motion of the Rif Mountains with respect to Africa. We use block modeling, constrained by mapped surface faults and seismicity to estimate the geometry and rates of strain accumulation on plate boundary structures. Our preferred plate boundary geometry includes one block between Iberia and Africa including the SW Betics, Alboran Sea, and central Rif. This geometry provides a good fit to the observed motions, suggesting a wide transpressive boundary in the westernmost Mediterranean, with deformation mainly accommodated by the Gloria-Azores fault system to the West and the Rif-Tell lineament to the East. Block boundaries encompass aspects of earlier interpretations suggesting three main deformation styles: (i) extension along the NE-SW trending Trans-Alboran shear zone, (ii) dextral strike-slip in the Betics corresponding to a well defined E-W seismic lineament, and (iii) right lateral strike-slip motion extending West to the Azores and right-lateral motion with compression extending East along the Algerian Tell. We interpret differential motion in the Rif-Alboran-Betic system to be driven both by surface processes related the Africa-Eurasia oblique convergence and sub-crustal dynamic processes associated with the long history of subduction of the Neotethys ocean lithosphere. The dextral slip identified in the Betic Mountains in Southern Spain may be related to the offshore fault that produced the Great 1755 Lisbon Earthquake, and as such may represent a significant seismic hazard for the West Mediterranean region.
ISSN: 0012-821X

hal-00618337
https://hal.archives-ouvertes.fr/hal-00618337
DOI : 10.1016/j.epsl.2011.05.048

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
Saint Ann's Bay is the capital of the parish of Saint Ann, Jamaica. In 1494, Christopher Columbus landed in the area and named the spot Santa Gloria. The first building on the right, in the foreground, is Frank Watson's Off Course Betting establishment. This is a view of the beach from Wharf Street. Slide labeled Jam. St. Ann's Bay near where Col. landed.
Jamaica -- Caribbean region -- Saint Ann's Bay, Saint Ann

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
http://ufdc.ufl.edu/AA00030973/00001

Résumé : The slides were taken on collecting trips sponsored by the William L. Bryant Foundation, where books, music and art indigenous to the regions were gathered. The are organized by geographical location.
In the foreground, the building sign says "Frank Watson's Off Course Betting: The name you know and trust." On the lower level of the building is a sign for a barber salon. There is an advertising sign on the corner of the street that says, "You don't have to get pregnant." The building on the right is the Saint Ann's Bay Courthouse in the parish of Saint Ann, Jamaica, which was built in 1860. Slide labeled Jam. St. Ann's Bay.
Jamaica -- Caribbean region -- Saint Ann's Bay, Saint Ann

Droits : All rights to images are held by the respective holding institution. This image is posted publicly for non-profit educational uses, excluding printed publication. For permission to reproduce images and/or for copyright information contact Special Collections & University Archives, University of Central Florida Libraries, Orlando, FL 32816 phone (407) 823-2576, email: speccoll@mail.ucf.edu
CFM1972_01a
http://ufdc.ufl.edu/AA00030970/00001

Éditeur(s) : Blackwell science
Résumé : This paper provides an exploratory analysis aiming to seek whether the colour of environmental noise theory could help in understanding the intriguing reproductive strategy of Atlantic bluefin tuna (BFT). A frequency-based approach based on spectral exponents, f(beta) with beta < 0, is chosen and applied on 10 biogeographical provinces covering the North Atlantic. The major BFT spawning area, i.e. the Mediterranean Sea, was the only one to display a pink power spectrum, whereas open ocean regions displayed more reddened fluctuations, i.e. greater variance at low frequencies. Environmental noise in the Mediterranean could, thus, offer more favourable characteristics on the long-term than the open ocean. The implications of these findings are discussed in regards to medium and long (possibly evolutionary) time scales.
Fisheries Oceanography (1054-6006) (Blackwell science), 2007-03 , Vol. 16 , N. 2 , P. 202-206

Droits : 2007 Blackwell science
http://archimer.ifremer.fr/doc/2007/publication-2437.pdf
DOI:10.1111/j.1365-2419.2006.00424.x
http://archimer.ifremer.fr/doc/00000/2437/

Éditeur(s) : Musée départemental d'archéologie précolombienne et de préhistoire de la Martinique
2012.0.1.241

Droits : Reproduction soumise à autorisation du Musée départemental d’archéologie précolombienne et de préhistoire de la Martinique
http://www.patrimoines-martinique.org/ark:/35569/a0114236047409quYWu

Extrait de : Santo Domingo : past and present with a glance at Hayti (p.369)
Résumé : Gravure représentant un moulin à sucre "primitif"
Siècle(s) traité(s) : 19
Droits : Domaine public
Provenance : Université des Antilles et de la Guyane. Service commun de la documentation
Permalien : http://www.manioc.org/images/HASH017a7b56af2412452017e087
HASH017a7b56af2412452017e087

Éditeur(s) : HAL CCSD
Résumé : International audience
Gevokizumab is a potent anti-interleukin (IL)-1 beta neutralizing monoclonal antibody (mAb), which may be used for treating inflammatory or autoimmune diseases. The present study was designed to characterize the potential effects of this mAb towards well-established IL-1 beta-mediated repression of hepatic drug detoxifying proteins, like cytochrome P450 (CYP) 3A4 and drug transporters. Primary cultured human hepatocytes were exposed to various concentrations of IL-1 beta in the absence or presence of gevokizumab (5 A mu g/mL); mRNA expression and activity of CYP3A4 and transporters were next determined. Gevokizumab was found to down-modulate, but not abolish, the repression of CYP3A4 and drug transporter mRNAs caused by IL-1 beta in human hepatocytes, through shifting up IL-1 beta half maximal inhibitory concentration (IC50) values by factors ranging from 6.8 to 10.4. The mAb concomitantly shifted IL-1 beta IC50 values towards CYP3A4 activity from 22.0 pg/mL (in the absence of gevokizumab) to 796 pg/mL (in the presence of gevokizumab) and counteracted the decrease of organic anion-transporting polypeptide activity occurring in response to 50 pg/mL IL-1 beta, but not that occurring at higher IL-1 beta concentration (1000 pg/mL). Gevokizumab attenuates, but not abolishes, IL-1 beta-mediated functional repression of CYP3A4 and drug transporters in human hepatocytes, which agrees with the fact that the mAb is considered as a modulator and not a blocker of IL-1 beta signaling. This attenuation of IL-1 beta-mediated down-regulation of hepatic detoxifying proteins by gevokizumab may have to be evaluated in terms of potential therapeutic protein drug-drug interactions when considering future development and therapeutic uses of this IL-1 beta neutralizing mAb.
ISSN: 0378-7966

hal-01616062
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01616062
DOI : 10.1007/s13318-017-0406-1

Éditeur(s) : Elsevier
Résumé : High P-wave velocities (7.1-7.8 km/s) lower crustal bodies (LCBs) imaged along volcanic margins are commonly interpreted as plume and break-up-related thick mafic underplating. This interpretation is partly challenged in this paper based on new seismic observations and modelling of the outer Voring Basin (Norway). An exceptional strong amplitude reflection, the T Reflection, is particularly well defined below the North Gjallar Ridge (NGR) between 7 and 8 s TWT. The T Reflection is located near the volcanic lava flows emplaced during the NE Atlantic breakup (similar to 55-54 Ma ago) and coincides with the top of the LCB, forming a mid-crustal dome. Based on structural and temporal relationships, we show that the dome clearly influences the structural development of the NGR and predates the continental breakup at least by 10-15 Ma. Using a thermo-kinematical model, we tried also to investigate and quantify the relationships between the extension, LCB and the magmatic production. Modelling suggests that significant Paleocene-Early Eocene magmatism can be produced without any temperature anomaly in the mantle if differential stretching occurs during the break-up initiation. The conclusion of 2D thermo-kinematical parametric analysis is that the magmatic model predicts, either little extension (beta < 2) with no melting or high extension (beta > 5) with significant melting along the outer Voring Basin. We suggest that the continental part of the LCB could not necessarily be breakup-related and so magmatic, as has often been stated previously. It is concluded here that the continental part of the LCB observed beneath the outer Voring Basin may be partly (or fully) attributed to inherited, high-pressure granulite/eclogite lower crustal rocks. The real amount of mafic material emplaced along the outer Voring Basin could be 20-40% less than thought.
Tectonophysics (0040-1951) (Elsevier), 2006 , Vol. 412 , N. 3-4 , P. 255-278

Droits : 2005 Elsevier B.V. All rights reserved
http://archimer.ifremer.fr/doc/2006/publication-1042.pdf
DOI:10.1016/j.tecto.2005.10.038
http://archimer.ifremer.fr/doc/00000/1042/

Éditeur(s) : Université des Antilles Université LAVAL Aix-Marseille Université UFAC Brésil
Extrait de : "Métissages : chercher, penser, créer, façonner et dire la culture" : colloque international, du 4 au 6 juin 2018. Université des Antilles
Description : À mieux les observer, l'univers naturel, le monde social, de même que l'homme, sont d'exceptionnels pots de sons à la richesse insondable. En effet, nul recoin ne s'en trouve privé, et l'homme, en tout lieu et en tout temps, a toujours eu les sons dans la peau, sans oublier les peaux des bêtes dont il se sert pour fabriquer des membranophones, toutes sortes de tambours. Et les sons produits sont une somme de relations, un pot de mélanges et de rapports en tous genres. Ils se font dans la société, dans la nature et même au-delà. Aussi ces sons, émis ici et là en ondes tonales et/ou bruiteuses, changent-ils, si promptement, si exactement, en quelques vérités animées voire en universelles aventures.

Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V18210
V18210

Éditeur(s) : Direction Générale des Travaux Publics Direction Générale des Travaux Publics ( Haiti )
Résumé : This collection of over 5,000 black and white photographs held by the National Archives of Haiti dates from 1918 to 1945. It contains images of public buildings before and after restoration, public works, monuments, and the visits of U.S. Presidents and other officials.
Haiti

Droits : All rights reserved by the National Archives of Haiti.
11046

Éditeur(s) : HAL CCSD American Chemical Society
Résumé : International audience
2-Amino-9H-pyrido[2,3-b]indole (AalphaC) is the most abundant carcinogenic heterocyclic aromatic amine (HAA) formed in mainstream tobacco smoke. AalphaC is a liver carcinogen in rodents, but its carcinogenic potential in humans is not known. To obtain a better understanding of the genotoxicity of AalphaC in humans, we have investigated its metabolism and its ability to form DNA adducts in human hepatocytes. Primary human hepatocytes were treated with AalphaC at doses ranging from 0.1-50 muM, and the metabolites were characterized by ultra-performance LC/ion trap multistage mass spectrometry (UPLC/MSn). Six major metabolites were identified: a ring-oxidized doubly conjugated metabolite, N2-acetyl-2-amino-9H-pyrido[2,3-b]indole-6-yl-oxo-(beta-d-glucuronic acid) (N2-acetyl-AalphaC-6-O-Gluc); two ring-oxidized glucuronide (Gluc) conjugates: 2-amino-9H-pyrido[2,3-b]indol-3-yl-oxo-(beta-d-glucuronic acid) (AalphaC-3-O-Gluc) and 2-amino-9H-pyrido[2,3-b]indol-6-yl-oxo-(beta-d-glucuronic acid) (AalphaC-6-O-Gluc); two sulfate conjugates, 2-amino-9H-pyrido[2,3-b]indol-3-yl sulfate (AalphaC-3-O-SO3H) and 2-amino-9H-pyrido[2,3-b]indol-6-yl sulfate (AalphaC-6-O-SO3H); and the Gluc conjugate, N2-(beta-d-glucosidurony1)-2-amino-9H-pyrido[2,3-b]indole (AalphaC-N2-Gluc). In addition, four minor metabolites were identified: N2-acetyl-9H-pyrido[2,3-b]indol-3-yl sulfate (N2-acetyl-AalphaC-3-O-SO3H), N2-acetyl-9H-pyrido[2,3-b]indol-6-yl sulfate (N2-acetyl-AalphaC-6-O-SO3H), N2-acetyl-2-amino-9H-pyrido[2,3-b]indol-3-yl-oxo-(beta-d-glucuronic acid) (N2-acetyl-AalphaC-3-O-Gluc), and O-(beta-d-glucosidurony1)-2-hydroxyamino-9H-pyrido[2,3-b]indole (AalphaC-HN2-O-Gluc). The latter metabolite, AalphaC-HN2-O-Gluc is a reactive intermediate that binds to DNA to form the covalent adduct N-(2'-deoxyguanosin-8-yl)-2-amino-9H-pyrido[2,3-b]indole (dG-C8-AalphaC). Preincubation of hepatocytes with furafylline, a selective mechanism-based inhibitor of P450 1A2, resulted in a strong decrease in the formation of AalphaC-HN2-O-Gluc and a concomitant decrease in DNA adduct formation. Our findings describe the major pathways of metabolism of AalphaC in primary human hepatocytes and reveal the importance of N-acetylation and glucuronidation in metabolism of AalphaC. P450 1A2 is a major isoform involved in the bioactivation of AalphaC to form the reactive AalphaC-HN2-O-Gluc conjugate and AalphaC-DNA adducts.
ISSN: 0893-228X

anses-01419468
https://hal-anses.archives-ouvertes.fr/anses-01419468
https://hal-anses.archives-ouvertes.fr/anses-01419468/document
https://hal-anses.archives-ouvertes.fr/anses-01419468/file/Bellamri%20et%20al.%20-%202016%20-%20Metabolism%20of%20the%20Tobacco%20Carcinogen%202-Amino-9H-py.pdf
DOI : 10.1021/acs.chemrestox.6b00394

Extrait de : Santo Domingo : past and present with a glance at Hayti (p.95)
Résumé : Gravure représentant un moulin à sucre français
Siècle(s) traité(s) : 18
Droits : Domaine public
Provenance : Université des Antilles et de la Guyane. Service commun de la documentation
Permalien : http://www.manioc.org/images/HASH01aa0e64046d379122cb8f91
HASH01aa0e64046d379122cb8f91