Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
BACKGROUND: In Guadeloupe and Martinique, two French Overseas Departments, colorectal cancer (CRC) has become an essential public health issue. However, little is known about CRC characteristics and the p53 status in these populations, particularly in Guadeloupe, whereas certification of a cancer registry has been recently validated. METHODS: This was a descriptive retrospective study of 201 patients who, between 1995 and 2000, underwent surgery for CRC in the Guadeloupe Teaching Hospital (GlpeTH; 83 patients) and in the Martinique Teaching Hospital (MqueTH; 118 patients). The clinicopathological features and the p53 expression, evaluated with immunohistochemistry, were compared at the time of diagnosis. A relationship between these parameters and the p53 expression was also studied. Data were analysed, using the SPSS computer software version 17.0. RESULTS: No statistical difference was found between the two groups of patients regarding age (p = 0.60), percentage of young patients (<=50 years; p = 0.94)), sex (p = 0.47), histological type (p = 0.073) and tumour sites (p = 0.65), although the GlpeTH patients were diagnosed with more distal colon cancers (54.2%) than the Mque TH patients (47.4%). By contrast, a significant difference was found regarding the tumour grade (p < 0.0001), the pTNM stage (p = 0.045) and the pT stage (p < 0.0001). Regarding p53 expression, solely for the MqueTH patients, nuclear expression was associated with pTNM, the percentage of p53 negative tumours increasing with the progression of the pTNM stages (p = 0.029). CONCLUSIONS: For the first time, this study reveals discrepancies in clinicopathological features and in the p53 status between the two groups of patients. The GlpeTH patients were diagnosed with more moderated CRCs but with few CRCs at pTNM IV stage. By contrast, the MqueTH patients were diagnosed with more differentiated tumours, but with many more CRCs at pTNM IV stage. This paradox may be due to differences in tumour location (distal vs proximal), multiplicity of the genetic profiles of patients, or patients getting treatment elsewhere. Although our study is limited due to its small size, it emphasizes the originality of our results.
ISSN: 1472-6890

inserm-00971313
http://www.hal.inserm.fr/inserm-00971313
http://www.hal.inserm.fr/inserm-00971313/document
http://www.hal.inserm.fr/inserm-00971313/file/1472-6890-14-12.pdf
DOI : 10.1186/1472-6890-14-12

Éditeur(s) : Impr. nationale Impr. nationale ( Port-au-Prince )
Résumé : (Dates or Sequential Designation) Print began: 1870.
(Numbering Peculiarities) None published 1887-1890; 1892-1915?
(Numbering Peculiarities) Numbering dropped with no. 22. (1891)?
(Issuing Body) 1946 issued by the Comité exécutif militaire, which was in power at this time.
At head of title, <1916-1957>: République d'Haïti; Département de la justice.
Edition statement starts appearing in 1916.
Bulletin for 1891, "publié avec la haute approbation de M. le secrétaire d'État de l'intérieur," was published in Paris by Ch. Dunod & P. Vicq.
Haiti
Haïti

643540980

Éditeur(s) : HAL CCSD Université des Antilles
Résumé : International audience
Cruise tourism is a sector that is rapidly expanding (16 million passengers in 2011). Today, cruising remains an essentially American affair, dominated by North American clients whose preferred destination is the Caribbean Sea. American cruise circuits continue to extend and diversify from the Panama Canal to the edge of Alaska. Meanwhile, cruises strengthen their position on the Mediterranean and Baltic Seas and has launched in East Asia from shores of the South China Sea to major rivers. Between continuity and recomposition, the cruise industry faces several challenges such as the limits of overcapacity (more than 6,000 passengers on board), its relationship with the host territories (ports of call), and the renewal of the “cruise” products.
Le tourisme de croisière est un secteur d’activité en pleine expansion (16 millions de passagers en 2011). De nos jours, la croisière reste encore une affaire essentiellement américaine, dominée par les clientèles nord-américaines, et dont le champ spatial privilégié est la mer des Caraïbes. Les circuits américains de la croisière s’étendent et se diversifient, du canal du Panama aux confins de l’Alaska. Parallèlement, la croisière conforte sa position sur les mers méditerranéenne et baltique et se déploie en Asie orientale, des rivages de la mer de Chine aux grands fleuves. Entre permanences et recompositions, l’industrie de la croisière doit relever plusieurs défis tels que les limites du gigantisme (plus de 6 000 passagers à bord), ses relations avec les territoires d’accueil (les ports d’escales), le renouvellement du produit « croisière ».
ISSN: 1779-0980

Droits : http://creativecommons.org/licenses/by-nc/
hal-01368523
https://hal.univ-antilles.fr/hal-01368523
https://hal.univ-antilles.fr/hal-01368523/document
https://hal.univ-antilles.fr/hal-01368523/file/le-tourisme-de-croisiere-dans-le-monde-permanences-et-recompositions%20%281%29.pdf
DOI : 10.4000/etudescaribeennes.5629

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Le tourisme de croisière est un secteur d’activité en pleine expansion (16 millions de passagers en 2011). De nos jours, la croisière reste encore une affaire essentiellement américaine, dominée par les clientèles nord-américaines, et dont le champ spatial privilégié est la mer des Caraïbes. Les circuits américains de la croisière s’étendent et se diversifient, du canal du Panama aux confins de l’Alaska. Parallèlement, la croisière conforte sa position sur les mers méditerranéenne et baltique et se déploie en Asie orientale, des rivages de la mer de Chine aux grands fleuves. Entre permanences et recompositions, l’industrie de la croisière doit relever plusieurs défis tels que les limites du gigantisme (plus de 6 000 passagers à bord), ses relations avec les territoires d’accueil (les ports d’escales), le renouvellement du produit « croisière ».
Cruise tourism is a sector that is rapidly expanding (16 million passengers in 2011). Today, cruising remains an essentially American affair, dominated by North American clients whose preferred destination is the Caribbean Sea. American cruise circuits continue to extend and diversify from the Panama Canal to the edge of Alaska. Meanwhile, cruises strengthen their position on the Mediterranean and Baltic Seas and has launched in East Asia from shores of the South China Sea to major rivers. Between continuity and recomposition, the cruise industry faces several challenges such as the limits of overcapacity (more than 6,000 passengers on board), its relationship with the host territories (ports of call), and the renewal of the “cruise” products.
Amérique du Nord
Caraïbes

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5629
http://journals.openedition.org/etudescaribeennes/5629

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
ISSN: 0003-4975

hal-01563338
http://hal.univ-brest.fr/hal-01563338
DOI : 10.1016/j.athoracsur.2016.03.093
PUBMED : 27262916

Éditeur(s) : HAL CCSD
Résumé : International audience
Leishmania parasites induce an immunomodulation by subverting the host immune response towards a CD4(+) Th2 lymphocytic cell response that favors parasite persistence. Here, we report that after successful treatment of visceral leishmaniasis due to Leishmania infantum, an immune reconstitution syndrome revealing hip septic arthritis was associated with a switch from Th2 towards a Th1 cytokine profile, and a decrease in the level of immunomodulating factors, such as soluble HLA-G and indoleamine 2,3-dioxygenase (IDO) activity. We then measured IDO activity in a cohort of 39 patients and uninfected control subjects. Results showed significantly enhanced IDO activity in patients with visceral Leishmania infection, compared with uninfected control subjects (P < 0.001), but also compared with treated patients (P < 0.05). A decrease in IDO activity could constitute a relevant biomarker for the restoration of the immune response during visceral leishmaniasis.
Innate Immunity

inserm-00818884
http://www.hal.inserm.fr/inserm-00818884
DOI : 10.1177/1753425912473170
PUBMED : 23413147

Résumé : Ce mémoire synthétise les travaux récents sur différents corps sableux de plate-forme. Il est basé sur l'analyse de données géophysiques et sédimentologiques provenant essentiellement des marges françaises (Manche, Atlantique, Méditerranée) et de la Mer de Chine de l'Est.

Droits : Université des Sciences et Technologies de Lille
http://archimer.ifremer.fr/doc/00034/14552/11801.pdf
http://archimer.ifremer.fr/doc/00034/14552/

Éditeur(s) : HAL CCSD
Résumé : International audience
Background: The aim of this study was to identify the predictive factors of HIV disclosure to the sex partner in HIV pregnant women in Cayenne (French Guiana). Methods: A case control study was conducted including all deliveries in Cayenne from 2003 to 2010. For each case, a standardized questionnaire including epidemiological, clinical, and biological data was administered. Thirty-four women in the first group and 95 in the control group were included in the study. Results: The logistic regression showed that the variables that independently predicted HIV disclosure to the sex partner were the existence of a profession (OR=5.62, IC95% =1.3-24.26, p=0.021), disclosure to the doctor (OR=12.65, IC95% =2.87-55.8, p<0.001), the negative representations of HIV (OR=5.99, IC95% =1.17-30.69, p=0.032). The partner's HIV status was also linked to the outcome (OR=0.01, IC95% =0.001-0.07, p<0.001). Conclusion: These predictive factors should be considered in positive prevention programs and prevention of mother to child transmission.
Epidemiol

inserm-00915113
http://www.hal.inserm.fr/inserm-00915113
http://www.hal.inserm.fr/inserm-00915113/document
http://www.hal.inserm.fr/inserm-00915113/file/2012_Elenga_-_Predictive_Factorssur HIV_Status_Disclosure_to_Sex_Partner_in_Pregnant_women_in_cayenne_french_guiana.pdf
DOI : 10.4172/2161-1165.1000116

Éditeur(s) : INRA : Institut National de la Recherche Agronomique Université des Antilles. Service commun de la documentation Caribbean Food Crops Society (CFCS)
Extrait de : 52e congrès annuel de la Société caribéenne des plantes alimentaires / 52nd annual meeting of the Caribbean food crops society (CFCS), du 10 au 16 juillet 2016. INRA, CFCS
Description : Farmers are very inventive, but their innovations often remain confined to their farm, or to small local networks. And the interest they might have for farmers other than their inventors is seldom analyzed. Tracking on-farm innovations aims at finding technical or organizational innovations designed by farmers, to characterize their agronomic, economic and environmental performance and analyze the conditions in which this performance is expressed. The talk presents the various stages of this tracking approach, applied to innovative cropping systems, basing on a variety of recent works, in France, Argentine, Burkina Faso and China: (1) Defining what we are looking for; (2) Identifying innovative systems; (3) Describing and characterizing innovative systems; (4) Assessing innovative systems; (5) Specifying the conditions for the success of innovative systems. The results of the tracking are aimed not only at the farmers, but at their advisors and researchers too: (i) Innovative and effective cropping systems, which can be a source of inspiration for farmers; (ii) Confirmation of the interest of a principle for reasoning cropping systems; (iii) Innovative practices, analyzed within a systemic framework, which can serve as bricks for the design of new systems; (iv) Questions to be looked into more thoroughly by experimentation. Compared to traditional approaches in agronomy, tracking innovative cropping systems provides a double break: break with a top-down approach, where agricultural R & D is regarded as the only source of innovation: by mobilizing the innovative capacities of farmers, tracking increases our collective capacity to invent new practices or new cropping systems, by using not only technical and scientific knowledge, but also the empirical knowledge, that is so rich in agriculture. And break with the primacy given to experimentation, as a source for the production of knowledge and the assessment of innovations. Les agriculteurs sont très inventifs, mais leurs innovations demeurent souvent confinées à leur ferme, ou à de petits réseaux locaux. Et l'intérêt qu'elles pourraient avoir pour des agriculteurs autres que leurs inventeurs est rarement analysé. Le cheminement des innovations à la ferme vise à trouver les innovations techniques ou organisationnelles conçues par des agriculteurs, pour caractériser leur agronomique, économique et la performance environnementale et pour analyser les conditions en lesquelles ces résultats sont exprimés. L'entretien présente les diverses étapes de cette approche de cheminement, appliquées aux systèmes d'emblavage innovateurs, basant sur un grand choix de travaux récents, les Frances, l'Argentin, au Burkina Faso et en Chine : (1) définissant ce que nous recherchons ; (2) identification des systèmes innovateurs ; (3) description et caractérisation des systèmes innovateurs ; (4) l'évaluation des systèmes innovateurs ; (5) spécification des conditions pour le succès des systèmes innovateurs. Les résultats du cheminement sont visés non seulement les agriculteurs, mais leurs conseillers et chercheurs trop : (i) systèmes d'emblavage innovateurs et efficaces, qui peuvent être une source d'inspiration pour des agriculteurs ; (ii) confirmation d'intérêt d'un principe pour les systèmes d'emblavage de motif ; (iii) pratiques innovatrices, analysées dans un cadre systémique, qui peut servir de briques à la conception de nouveaux systèmes ; (iv) questions à regarder dans plus complètement par expérimentation. Comparé aux approches traditionnelles en agronomie, le cheminement des systèmes d'emblavage innovateurs fournit une double coupure : cassez avec une approche hiérarchisée, où la R&D agricole est considérée comme la seule source d'innovation : en mobilisant les capacités innovatrices d'agriculteurs, le cheminement augmente notre capacité collective d'inventer de nouvelles pratiques ou nouveaux systèmes d'emblavage, à l'aide non seulement de technique et de la connaissance scientifique, mais également la connaissance empirique, qui est si riche en agriculture. Et coupure avec la primauté donnée à l'expérimentation, comme source pour la production de la connaissance et de l'évaluation des innovations.
Siècle(s) traité(s) : 21
Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V16242
V16242

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
The effects of biodiversity on the transmission of infectious diseases now stand as a cornerstone of many public health policies. The upper Amazonia and Guyana shield are hot-spots of biodiversity that offer genuine opportunities to explore the relationship between the risk of transmission of Chagas disease and the diversity of its triatomine vectors. Over 730 triato-mines were light-trapped in four geomorphological landscapes shaping French-Guiana, and we determined their taxonomic status and infection by Trypanosoma cruzi. We used a model selection approach to unravel the spatial and temporal variations in species abundance , diversity and infection. The vector community in French-Guiana is typically made of one key species (Panstrongylus geniculatus) that is more abundant than three secondary species combined (Rhodnius pictipes, Panstrongylus lignarius and Eratyrus mucronatus), and four other species that complete the assemblage. Although the overall abundance of adult triatomines does not vary across French-Guiana, their diversity increases along a coastal-inland gradient. These variations unravelled a non-monotonic relationship between vector biodiversity and the risk of transmission of Chagas disease, so that intermediate biodiversity levels are associated with the lowest risks. We also observed biannual variations in triatomine abundance, representing the first report of a biannual pattern in the risk of Cha-gas disease transmission. Those variations were highly and negatively correlated with the average monthly rainfall. We discuss the implications of these patterns for the transmission of T. cruzi by assemblages of triatomine species, and for the dual challenge of controlling Amazonian vector communities that are made of both highly diverse and mostly intrusive species.
ISSN: 1935-2727

Droits : http://creativecommons.org/licenses/by/
hal-01298091
https://hal-univ-perp.archives-ouvertes.fr/hal-01298091
https://hal-univ-perp.archives-ouvertes.fr/hal-01298091/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01298091/file/journal.pntd.0004427.PDF
DOI : 10.1371/journal.pntd.0004427

Éditeur(s) : HAL CCSD
Résumé : International audience
Kisspeptins are well known as mediators of the coordinated communication between the brain-pituitary axis and the gonads in many vertebrates. To test the hypothesis that gonadal steroids regulate kiss1 and kiss2 mRNA expression in European sea bass (a teleost fish), we examined the brains of gonad-intact (control) and castrated animals, as well as castrated males (GDX) and ovariectomized females (OVX) that received testosterone (T) and estradiol (E2) replacement, respectively, during recrudescence. In GDX males, low expression of kiss1 mRNA is observed by in situ hybridization in the caudal hypothalamus (CH) and the mediobasal hypothalamus (MBH), although hypothalamic changes in kiss1 mRNA levels were not statistically different among the groups, as revealed by real-Time PCR. However, T strongly decreased kiss2 expression levels in the hypothalamus, which was documented in the MBH and the nucleus of the lateral recess (NRLd) in GDX T-Treated sea bass males. Conversely, it appears that E2 evokes lowkiss1mRNAin the CH, while there were cells expressing kiss2 in the MBH and NRLd in these OVX females. These results demonstrate that kisspeptin neurons are presumably sensitive to the feedback actions of sex steroids in the sea bass, suggesting that the MBH represents a major site for sex steroid actions on kisspeptins in this species. Also, recent data provide evidence that both positive and negative actions occur in key factors involved in sea bass reproductive function, including changes in the expression of gnrh-1/gonadotropin, cyp19b, er and ar genes and sex steroid and gonadotropin plasma levels in this teleost fish. © 2016. Published by The Company of Biologists Ltd.
Journal of Experimental Biology

hal-01406072
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01406072
DOI : 10.1242/jeb.137364
PUBMED : 27591305

Éditeur(s) : HAL CCSD Public Library of Science
Résumé : International audience
BACKGROUND: Histoplasmosis is an endemic fungal infection in French Guiana. It is the most common AIDS-defining illness and the leading cause of AIDS-related deaths. Diagnosis is difficult, but in the past 2 decades, it has improved in this French overseas territory which offers an interesting model of Amazonian pathogen ecology. The objectives of the present study were to describe the temporal trends of incidence and mortality indicators for HIV-associated histoplasmosis in French Guiana. METHODS: A retrospective study was conducted to describe early mortality rates observed in persons diagnosed with incident cases of HIV-associated Histoplasma capsulatum var. capsulatum histoplasmosis admitted in one of the three main hospitals in French Guiana between 1992 and 2011. Early mortality was defined by death occurring within 30 days after antifungal treatment initiation. Data were collected on standardized case report forms and analysed using standard statistical methods. RESULTS: There were 124 deaths (45.3%) and 46 early deaths (16.8%) among 274 patients. Three time periods of particular interest were identified: 1992-1997, 1998-2004 and 2005-2011. The two main temporal trends were: the proportion of early deaths among annual incident histoplasmosis cases significantly declined four fold (χ2, p<0.0001) and the number of annual incident histoplasmosis cases increased three fold between 1992-1997 and 1998-2004, and subsequently stabilized. CONCLUSION: From an occasional exotic diagnosis, AIDS-related histoplasmosis became the top AIDS-defining event in French Guiana. This was accompanied by a spectacular decrease of early mortality related to histoplasmosis, consistent with North American reference center mortality rates. The present example testifies that rapid progress could be at reach if awareness increases and leads to clinical and laboratory capacity building in order to diagnose and treat this curable disease.
ISSN: 1935-2727

inserm-01065109
http://www.hal.inserm.fr/inserm-01065109
http://www.hal.inserm.fr/inserm-01065109/document
http://www.hal.inserm.fr/inserm-01065109/file/PLOS_Neglected_Tropical_Dis_2014.pdf
http://www.hal.inserm.fr/inserm-01065109/file/2014_Adenis_-_HIV-associated_histoplasmosis_early_mor.pdf

Éditeur(s) : HAL CCSD American Society of Tropical Medicine and Hygiene
Résumé : International audience
In disease-endemic areas, histoplasmosis is the main differential diagnosis for tuberculosis among human immunodeficiency virus (HIV)-infected patients. However, no study has compared the two diseases. Thus, the objective of this study was to compare tuberculosis and histoplasmosis in HIV-infected patients. A population of 205 HIV-infected patients (99 with tuberculosis and 106 with histoplasmosis) hospitalized in Cayenne, French Guiana during January 1, 1997-December 31, 2008 were selected retrospectively from the French Hospital Database on HIV. Multivariate analysis showed that tuberculosis was associated with cough (adjusted odds ratio [AOR] = 0.20, 95% confidence interval [CI] = 0.05-0.73) and a C-reactive protein level > 70 mg/L (AOR = 0.98, 95% CI = 0.97-0.99). Variables associated with disseminated histoplasmosis were a γ-glutamyl transferase level > 72 IU/L (AOR = 4.99, 95% CI = 1.31-18.99), origin from French Guiana (AOR = 5.20, 95% CI = 1.30-20.73), disseminated localization (AOR = 6.40, 95% CI = 1.44-28.45), a concomitant opportunistic infection (AOR = 6.71, 95% CI = 1.50-29.96), a neutrophil count < 2,750 cells/mm(3) (AOR = 10.54, 95% CI = 2.83-39.24), a CD4 cell count < 60 cells/mm(3) (AOR = 11.62, 95% CI = 2.30-58.63), and a platelet count < 150,000/mm(3) (AOR = 19.20, 95% CI = 3.35-110.14). Tuberculosis and histoplasmosis have similarities, but some factors show a greater association with one of these diseases. Thus, adapted therapeutic choices can be made by using simple clinical and paraclinical criteria.
ISSN: 0002-9637

inserm-01065027
http://www.hal.inserm.fr/inserm-01065027
http://www.hal.inserm.fr/inserm-01065027/document
http://www.hal.inserm.fr/inserm-01065027/file/2014_Adenis_-_Tuberculosis_and_Histoplasmosis_among_HIV.pdf
DOI : 10.4269/ajtmh.13-0084

Éditeur(s) : HAL CCSD Lelivredart
Résumé : Beau livre Préface de Serge Patient (1934- ), écrivain et poète, lauréat du prix Carbet 2001
De la récolte à la mise en fûts
Les rhums Saint-Maurice

ISBN : 978-2-35532-152-8
hal-01601745
https://hal.archives-ouvertes.fr/hal-01601745
PRODINRA : 393937

Éditeur(s) : HAL CCSD Geological Society of America
Résumé : International audience
Mechanisms that control seismic activity in low strain rate areas such as western Europe remain poorly understood. For example, in spite of low shortening rates of <0.5 mm/ yr, the Western Alps and the Pyrenees are underlain by moderate but frequent seismicity detectable by instruments. Beneath the elevated part of these mountain ranges, analysis of earthquake focal mechanisms indicates extension, which is commonly interpreted as the result of gravitational collapse. Here we show that erosional processes are the predominant control on present-day deformation and seismicity. We demonstrate, using fi nite element modeling, that erosion induces extension and rock uplift of the elevated region of mountain ranges accommodating relatively low overall convergence. Our results suggest that an erosion rate of ~1 mm/yr can lead to extension in mountain ranges accommodating signifi cant shortening of <3 mm/yr. Based on this study, the seismotectonic framework and seismic hazard assessment for low strain rate areas need to be revisited, because erosion-related earthquakes could increase seismic hazard.
ISSN: 0091-7613

insu-00817341
https://hal-insu.archives-ouvertes.fr/insu-00817341
DOI : 10.1130/G33942.1

Résumé : Les diverses provinces de notre Empire Colonial d'Asie, qui forment l'Indo-Chine méridionale, sont comprises, au point de vue ichtyologique, dans une zone spéciale que les naturalistes dénomment « Zone Indienne ». Elle s'étend sur tout le Sud de l'Asie, depuis le Tigre jusqu'au Yang-Tsé-Kyang, ou fleuve Bleu, englobant une région maritime et fluviale exceptionnellement riche en poissons. Dans une remarquable étude : « Les poissons de la Basse Cochinchine et du Cambodge », le docteur Tirant affirme qu'on compte dans cette zone plus de 1.907 espèces marines sur 3.587 décrites dans les auteurs classiques et 625 espèces d'eau douce sur 2.269 espèces connues.

Droits : 1911 Augustin Challamel, Editeur, Paris
http://archimer.ifremer.fr/doc/00032/14303/11582.pdf
http://archimer.ifremer.fr/doc/00032/14303/

Éditeur(s) : HAL CCSD SAGE Publications
Résumé : International audience
In Western French Guiana there was a dramatic increase in HIV-prevalence between 1990 and 2000. The present study describes the causes of fever among HIV patients hospitalized in the medical ward of the only hospital in the western part of French Guiana. A retrospective descriptive study was conducted between January 1st 2008 and June 30th 2010 in the department of medicine of Saint Laurent du Maroni Hospital. The main characteristics of 67 patients having presented with fever in the first 48 hours of hospitalization were described. Among patients with CD4<200/mm3 the main febrile opportunistic infection was disseminated histoplasmosis (41.1%). Among patients with CD4 counts <50/mm3 and fever without focal points 85.7% had disseminated histoplasmosis. Three patients died and all had disseminated histoplasmosis. Disseminated histoplasmosis is the most common febrile opportunistic infection in western French Guiana. Primary prophylaxis with itraconazole among immunocompromised patients seems warranted.
ISSN: 0956-4624

inserm-01082409
http://www.hal.inserm.fr/inserm-01082409
http://www.hal.inserm.fr/inserm-01082409/document
http://www.hal.inserm.fr/inserm-01082409/file/2014%2C%20Vantilcke%20-%20Fever%20and%20HIV.pdf
http://www.hal.inserm.fr/inserm-01082409/file/Histoplasmosis_tab_2%5B1%5D%20revised.pdf

Éditeur(s) : HAL CCSD Springer-Verlag
Résumé : absent
Genome mapping and molecular breeding in plants. Forest trees

ISBN : 978-3-5403-4540-4
hal-01189181
https://hal.archives-ouvertes.fr/hal-01189181
PRODINRA : 12233

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Tourism economic development and traditional culture preservation has been a topic of concern and discussion in academic fields. Based on the development of the tourism economy in Xijiang Miao Village of China, the paper focuses on the analysis of the preservation methods and effects of traditional culture in Chinese ethnic communities. Finally, it points out that the preservation of traditional cultures and tourism development in ethnic communities are not always contradictory. Including the community’s participation can help achieve a “win-win” situation for all actors.
Le développement économique du tourisme et la préservation de la culture traditionnelle est un sujet de préoccupation et de discussion dans les milieux universitaires. Basé sur le développement de l'économie du tourisme du village Miao Xijiang en Chine, cet article se concentre sur l'analyse des méthodes de préservation et leurs conséquences sur la culture traditionnelle des communautés ethniques chinoises. Enfin, l’étude souligne que la préservation des cultures traditionnelles et le développement du tourisme dans les communautés ethniques ne sont pas toujours contradictoires ; la participation de la communauté peut aider à atteindre une situation "gagnant-gagnant" pour tous les acteurs.
Chine
Guizhou
Leisha

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.7556
http://journals.openedition.org/etudescaribeennes/7556

Éditeur(s) : HAL CCSD
Résumé : National audience
Il virus dell’epatite C (HCV), a trasmissione parenterale, è stato identificato nel 1989 come il virus responsabile delle epatiti «non A non B». L’infezione colpisce circa 170 milioni di persone nel mondo e 200 000 persone in Francia hanno una replicazione virale attiva. Nei paesi industrializzati, l’epidemia ha accompagnato lo sviluppo della trasfusione sanguigna e della tossicomania endovenosa. I test enzyme-linked immunosorbent assay che individuano gli anticorpi anti-HCV hanno permesso uno screening attendibile dell’infezione a partire dal 1992. La rilevazione dell’acido ribonucleico virale C permette la diagnosi dell’infezione cronica che fa seguito all’epatite acuta in circa l’80% dei casi. La gravità dell’infezione è legata allo sviluppo progressivo di una fibrosi epatica che conduce alla cirrosi dopo una mediana di evoluzione di 30-40 anni. La malattia è, così, responsabile di circa 350 000 decessi per anno nel mondo, legati, in parti uguali, all’insufficienza epatica e al carcinoma epatocellulare. Il trattamento ha compiuto enormi progressi in 20 anni e nuove molecole antivirali sono in corso di sviluppo clinico.
EMC - AKOS - Trattato di Medicina

hal-01154232
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01154232
DOI : 10.1016/S1634-7358(15)70635-2