Éditeur(s) : HAL CCSD
Résumé : International audience
AIM:We aimed to study the relationships between circulating 25-hydroxyvitamin D [25(OH)D], insulin resistance and leptin-to-adiponectin (L/A) ratio in Guadeloupean children and adolescents and to analyse the changes in 25(OH)D levels after a 1-year lifestyle intervention program.METHODS:25(OH)D concentrations were measured via a chemiluminescence assay. Cardiometabolic risk factors, homoeostasis model assessment of insulin resistance (HOMA-IR), and adipokines were measured. The lifestyle intervention included dietary counselling, regular physical activity.RESULTS:Among 117 girls and boys (11–15 years old, 31.6% obese), 40% had vitamin D deficiency (25(OH)D levels < 20 ng/mL). With linear regression models where 25(OH)D and HOMA-IR acted as independent variables and age, sex, BMI, L/A ratio as covariates, 25(OH)D was significantly associated with HOMA-IR alone (P = 0.036). HOMA-IR was also associated with BMI z-score ≥ 2, L/A ratio and an interaction term BMI z-score ≥ 2*L/A ratio (P < 0.001 for all). After one year, in 78 children/adolescent, mean serum 25(OH)D increased significantly from 21.4 ± 4.9 ng/mL at baseline to 23.2 ± 6.0 after 1 year; P = 0.003 whereas BMI z-score, HOMA-IR and L/A ratio decreased significantly (P = 0.003, P < 0.001 and P = 0.012; respectively).CONCLUSION:The association between 25(OH)D and HOMA-IR, independently of obesity and the high prevalence of vitamin D deficiency should be considered in order to prevent the later incidence of T2DM. A healthy lifestyle including non-sedentary and outdoor activities could be a way for improving vitamin D status.
Open Access Macedonian Journal of Medical Sciences

hal-01427889
http://hal.upmc.fr/hal-01427889
PUBMEDCENTRAL : PMC5175505

Éditeur(s) : Université des Antilles Tropiques Atrium Scène national - Martinique
Extrait de : "Rendre hommage à l'Atelier 45" : conférence, le 15 octobre 2016. Université des Antilles
Description : Enseignante d'histoire-géographie, docteur en histoire moderne, spécialiste de l'histoire de l'esclavage dans les Petites Antilles. Elle est l'auteure de plusieurs articles traitant de ces questions et de l'ouvrage « La canne à sucre et ses enjeux aux Antilles françaises ». Elle témoigne par un récit d'une rencontre enrichissante qui dura une année (la dernière), avec Monsieur Mystille. Personnage discret, qui a cependant participé et apporté à l'histoire de la Martinique. Érudit, amoureux de son île, de son patrimoine, il collectionnait les livres et les photos. Témoin « espiègle » des pages les plus importantes de notre histoire contemporaine, il aimait raconter sa Martinique. Cette rencontre, arrivée trop tardivement, lui permit, selon elle, d'appréhender différemment les hommes et les femmes qu'il avait côtoyés dans sa vie culturelle, politique et artistique.
Siècle(s) traité(s) : 21
Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V16297
V16297

Éditeur(s) : HAL CCSD American Diabetes Association
Résumé : International audience
OBJECTIVE: To compare incidences and risk factors for diabetes using seven definitions, with combinations of pharmacological treatment, fasting plasma glucose (FPG) ≥7.0 mmol/L, and HbA(1c) ≥6.5%. RESEARCH DESIGN AND METHODS: Participants aged 30-65 years from the Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) cohort were followed for 9 years. RESULTS: More men had incident diabetes as defined by FPG ≥7.0 mmol/L and/or treatment than by HbA(1c) ≥6.5% and/or treatment: 7.5% (140/1,867) and 5.3% (99/1,874), respectively (P < 0.009); for women incidences were similar: 3.2% (63/1,958) and 3.4% (66/1,954). Known risk factors predicted diabetes for almost all definitions. Among those with incident diabetes by FPG alone versus HbA(1c) alone, there were more men (78 vs. 35%), case patients were 8 years younger, and fewer were alcohol abstainers (12 vs. 35%) (all P < 0.005). A diabetes risk score discriminated well between those with and without incident diabetes for all definitions. CONCLUSIONS: In men, FPG definitions yielded more incident cases of diabetes than HbA(1c) definitions, in contrast with women. An FPG-derived risk score remained relevant for HbA(1c)-defined diabetes.
Diabetes Care

inserm-00739799
http://www.hal.inserm.fr/inserm-00739799
http://www.hal.inserm.fr/inserm-00739799/document
DOI : 10.2337/dc10-1581
PUBMED : 21346181

Résumé : Au début du vingtième siècle, une rupture radicale et fondatrice de modernité artistique eut lieu au Brésil. Cette modernité se démarque de celle d’Europe par la prise de conscience des distances géographiques, culturelles et politiques vis à vis de l’Europe et surtout de l’ancienne puissance coloniale, le Portugal, par la recherche de son identité à travers la multiplicité des métissages du Nouveau Monde, ses mythes et son histoire réelle décolonisée. L’avant-garde brésilienne émerge autour de 1928, à travers les Manifestes anthropophages d’Oswald de Andrade (1890-1954) qui est donc le fondateur des anthropophagies, que l’on peut définir comme un indianisme à rebours. Le ″mauvais sauvage″ exerce sa critique contre les impostures du monde. « La ″Descente anthropophagique″ n’est pas une révolution littéraire, ni sociale, ni politique, ni religieuse. Elle est tout cela à la fois ! Sa loi est simple : Ne m’intéresse que ce qui n’est pas à moi ! Loi de l’homme, loi de l’anthropophagie ! » . Elle prescrit donc la dévoration des modèles importés et leur digestion dans l’hybridation au nom de l’identité brésilienne, par déplacement de concepts freudiens : « L’anthropophagie c’est la transformation permanente du Tabou (manger de l’homme) en Totem (de l’identité brésilienne) ! » . Ici l’influence notable de la psychanalyse et de l’anthropologie est à resituer : le déplacement du tabou anthropophage demeure une transgression symbolique, une métaphore, mais la référence anthropophagique ne concerne pas que la période précolombienne, car elle se réactualise. Nous nous proposons d’étudier ce phénomène à travers quatre questions : 1°- Quelles relations existent entre l’anthropophagie, l’histoire, l’esthétique et l’idéologie ? 2°- Quelle est la place des femmes artistes brésiliennes dans l’émergence de ce mouvement, compte tenu de leur présence décisive dès l’origine ?3°- Compte tenu de la résurgence rhizomique de l’anthropophagie dans la 2e moitié du XXe siècle, y compris jusqu’à aujourd’hui, quelle est la place des femmes artistes dans ce phénomène ? Y a-t-il continuité avec l’époque fondatrice ?4°- Etant donné ce qui précède, peut-on déduire qu’il existe un courant spécifiquement féminin dans l’anthropophagie d’hier et d’aujourd’hui ? Quelle est son importance réelle ? Quelles sont ses relations et postures par rapport à la postmodernité et à la mondialisation de l’art contemporain ?
At the beginning of the twentieth century, in Brazil, a radical artistic rupture took place, which marked the beginning of a new era. The resulting modernity differed from its European counterpart by the awareness of geographical, cultural and political distances that alienated Brazil from Europe and more specifically from its former colonial owner, Portugal. Brazilian modernity sought to define its identity through important basic elements that constitute the stuff that the New World is made of: cross-breeding, mythology and post-colonialism. The Brazilian avant-garde emerged around 1928 with the publication of The Anthropophagy Manifesto by Oswald de Andrade (1890-1954), who is thus the founder of the Anthropophagy, that we can define as a backward step into a reinvented form of ″Amerindianness″. The ″bad savage″ voices his criticism against impostures of the world. « Anthropophagy art is not a literary revolution, nor is it a social plea, nor a political pamphlet, nor a religious tract. It is all these things at the same time. Its law is simple: everything that is not me is of interest to me. The law of men is the law of Anthropophagy ». It thus prescribes eating up imported models and digesting them through the process of hybridization in the name of Brazilian identity. By displacing Freudian concepts, «Anthropophagy is the permanent transformation of the Taboo (man-eating) into a Totem (Brazilian identity) ». The permeating influences of psychoanalysis and anthropology need to be put in perspective: the displacement of the anthropophagous taboo remains a symbolic act of transgression, a metaphor, but the anthropophagic reference does not concern the pre-Columbian period, because it is updated. We propose to study this phenomenon through four questions: 1°- What are the relations between Anthropophagy, history, esthetics and ideology? 2°- What is the place of women Brazilian artists in the emergence of this movement, taking into account their decisive presence right from the start? 3°- Taking into account the resurgence of Anthropophagy from the second half of the 20th century onwards, what is the place of women artists in this phenomenon? Are they pursuing the same interests as the founders of the movement?4°- Can we deduce that there exists a specifically female genre within the anthropophagic movement of yesterday and of today? If so, what is its relevance? Where does it stand with respect to the contemporary concepts of post-modernity and globalization in the present-day art world?

http://www.theses.fr/2014AGUY0766/document

Éditeur(s) : Université des Antilles
Extrait de : Les rencontres culturelles de la BU 2016-2017. Université des Antilles
Description : "Cri de mes racines" (Work in Progress). Le duo-danse Josiane Antourel et Yna Boulangé revisite ce spectacle composé par Jean-François Colombo, et conçu à l'origine sous la forme d'un solo pour J. Antourel. Ce travail de création et de réadaptation, expliquent les artistes, "puise ses forces dans les gestes quotidiens et traditionnels de la Martinique". Ceux-ci se conjuguent ici avec "l'image d'Haïti, celle de son relief sinueux, qui renvoie le reflet de la morphologie de la femme caribéenne. Ce chant du corps en évoque les combats, les révoltes et les douleurs : porte-parole de l'île, elle tient « debout » en lutte contre elle-même. Une métaphore poétique pour rappeler un système social et politique hostile, celui de nos contrées... celui d'Haïti en particulier". Le duo Boulangé-Antourel prolonge et poursuit, à la manière d'un hommage, l'engagement artistique du chorégraphe martiniquais Jean-François Colombo, décédé en 1996.

Droits : CC-BY-NC-ND - Attribution - Pas d'utilisation commerciale - Pas de modification
Permalien : http://www.manioc.org/fichiers/V17012
V17012

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : The aim of this paper is to study Moroccan music festivals against the existing theories on globalization, while coming up with new concepts aimed at overcoming the problems often facing experts in popular culture and media studies who feel that globalization thesis lapses into fatal gestures of leveling, reductionism, and totalitarianism, especially when it tries to account for current discussions related to the circulation of artifacts and cultural texts. The general consensus has it that modern technologies have hugely altered the meaning and revolutionized the traditional functions attached to art and cultural industries. The grotesque circulation of western cultural artifacts is justifiably judged to be many times agonizing for theorists in cultural studies, linguistics and political science, etc who want to be sure that the unequal transmissions of products across the world will not harm local cultural, linguistic and economic capital of the less dominant other. Moroccan music festivals for instance are seen to be increasingly governed by a complex whirlpool of the far-too-melodramatic implications of today’s world global connections. In view of this, this paper, which borrows from data collected during between 2010 and 2011, will examine cultural industries, music festivals in general and the Essaouira festival in particular, in relation to world flows, while holding the argument that the appropriation of western artifacts locally has always been part of a not-so-novel process of mobility of what we call world cultural nomadictates (nomadic dictates). The paper gives a detailed definition of this concept and develops other new concepts (e.g. recurents, exclusives) related to the «glocal» face of culture and art in Morocco in an attempt to find an escape route outside the impasses of the globalization/cultural imperialism theses surrounding the study of cultural industries. To drive this idea home, we will open up the discussion at hand onto existing controversies around notions of place, authenticity, urbanism, tourism and consumption.
L'objectif de cette recherche est d’étudier les festivals de musique marocains en portant un regard critique sur les théories existantes de la mondialisation et en proposant de nouveaux concepts afin de surmonter les problèmes auxquels les théoriciens de la culture populaire et des médias se sont souvent confrontés. Selon eux, le concept de mondialisation sombre dans le réductionnisme et le totalitarisme, surtout lorsqu’il s’agit de la circulation des objets et des textes culturels. Un consensus général semble s’être développé autour de l’idée selon laquelle les technologies modernes ont considérablement altéré et révolutionné le sens et les fonctions traditionnelles de l'art et des industries culturelles. L'insolite diffusion des objets culturels occidentaux est à juste titre source d’angoisse pour les théoriciens des études culturelles, de la linguistique, et des sciences politiques qui veulent s'assurer que la transmission inégale des produits dans le monde ne nuira pas au capital local, culturel, linguistique et économique de l'autre (le moins dominant). Les festivals de musique marocains, par exemple, sont perçus comme étant de plus en plus tributaires des vicissitudes de la mondialisation actuelle. Dans cette perspective, cette recherche, s'inspire de données recueillies au cours de deux années de travail de terrain (2010/2011), et se penche sur les flux mondiaux de produits culturels qui mettent en interface les industries culturelles, les festivals de musique en général et celui d'Essaouira en particulier. Elle maintient l'idée selon laquelle l'appropriation des objets occidentaux par les communautés locales a toujours fait partie d'un processus de mobilité, qui n'est pas si récent, de ce que nous appelons les ‘nomadictâtes’ culturels du monde (dictâtes nomades). En explicitant la définition de ce concept, cette recherche développe d'autres concepts liés à la notion de glocalité de la culture et de l'art au Maroc. Enfin, elle suggère aussi une issue à l’impasse des théories de la mondialisation traditionnelles et celle de l’impérialisme culturel en particulier dans lesquelles l’étude des industries culturelles semble s’être emprisonnée. Pour ce faire, nous exposons le débat actuel sur les controverses autour des notions de lieu, d'authenticité, d'urbanisme, de tourisme, et de consommation.
Maroc

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5993
http://journals.openedition.org/etudescaribeennes/5993

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Well-designed and effectively managed networks of marine reserves can be effective tools for both fisheries management and biodiversity conservation. Connectivity, the demographic linking of local populations through the dispersal of individuals as larvae, juveniles or adults, is a key ecological factor to consider in marine reserve design, since it has important implications for the persistence of metapopulations and their recovery from disturbance. For marine reserves to protect biodiversity and enhance populations of species in fished areas, they must be able to sustain focal species (particularly fishery species) within their boundaries, and be spaced such that they can function as mutually replenishing networks whilst providing recruitment subsidies to fished areas. Thus the configuration (size, spacing and location) of individual reserves within a network should be informed by larval dispersal and movement patterns of the species for which protection is required. In the past, empirical data regarding larval dispersal and movement patterns of adults and juveniles of many tropical marine species have been unavailable or inaccessible to practitioners responsible for marine reserve design. Recent empirical studies using new technologies have also provided fresh insights into movement patterns of many species and redefined our understanding of connectivity among populations through larval dispersal. Our review of movement patterns of 34 families (210 species) of coral reef fishes demonstrates that movement patterns (home ranges, ontogenetic shifts and spawning migrations) vary among and within species, and are influenced by a range of factors (e.g. size, sex, behaviour, density, habitat characteristics, season, tide and time of day). Some species move <0.1–0.5 km (e.g. damselfishes, butterflyfishes and angelfishes), <0.5–3 km (e.g. most parrotfishes, goatfishes and surgeonfishes) or 3–10 km (e.g. large parrotfishes and wrasses), while others move tens to hundreds (e.g. some groupers, emperors, snappers and jacks) or thousands of kilometres (e.g. some sharks and tuna). Larval dispersal distances tend to be <5–15 km, and self-recruitment is common. Synthesising this information allows us, for the first time, to provide species, specific advice on the size, spacing and location of marine reserves in tropical marine ecosystems to maximise benefits for conservation and fisheries management for a range of taxa. We recommend that: (i) marine reserves should be more than twice the size of the home range of focal species (in all directions), thus marine reserves of various sizes will be required depending on which species require protection, how far they move, and if other effective protection is in place outside reserves; (ii) reserve spacing should be <15 km, with smaller reserves spaced more closely; and (iii) marine reserves should include habitats that are critical to the life history of focal species (e.g. home ranges, nursery grounds, migration corridors and spawning aggregations), and be located to accommodate movement patterns among these. We also provide practical advice for practitioners on how to use this information to design, evaluate and monitor the effectiveness of marine reserve networks within broader ecological, socioeconomic and management contexts.
ISSN: 1464-7931

Droits : http://creativecommons.org/licenses/by-nc-nd/
hal-01334353
https://hal-univ-perp.archives-ouvertes.fr/hal-01334353
https://hal-univ-perp.archives-ouvertes.fr/hal-01334353/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01334353/file/Green_et_al-2015-Biological_Reviews.pdf
DOI : 10.1111/brv.12155

Éditeur(s) : HAL CCSD
Résumé : International audience
BACKGROUND: The effects of pressure-controlled (PC) ventilation on the ventilatory and haemodynamic parameters during laparoscopy procedures had not been carefully assessed. This prospective cross-over study was undertaken to compare how volume-controlled (VC) and PC modes could affect pulmonary mechanics, gas exchange, and cardiac function in patients undergoing laparoscopy. METHODS: Twenty-one patients undergoing laparoscopic urological procedures had their lungs ventilated at the beginning with VC ventilation. PC ventilation was instituted at the end of the VC sequence. Ventilator settings were adjusted to keep tidal volume, respiratory rate, and Fi(o(2)) constant in every mode. A complete set of ventilatory, haemodynamic, and gas exchange parameters was obtained under VC after 40 min of pneumoperitoneum and 20 min after switching for PC. Transoesophageal echocardiography was performed in order to evaluate systolic and diastolic function of the heart. RESULTS: When VC was switched to PC, peak airway pressure decreased [mean (sd) 32 (6) vs 27 (6) cm H(2)O; P < 0.0001], peak inspiratory flow increased [17 (3) vs 48 (8) litre min(-1); P < 0.0001), and dynamic compliance improved [+15 (8)%]. No difference was noted for static airway pressure, static compliance, and arterial oxygenation. No significant change could be demonstrated in the systolic [left ventricular end-systolic wall stress 66 (16) vs 63 (14) x 10(3) dyn cm(-2) m(-2)] or diastolic function [early diastolic velocity 10.3 (2.5) vs 10.5 (2.7) cm s(-1)]. CONCLUSIONS: In this study, no short-term beneficial effect of PC ventilation could be demonstrated over conventional VC ventilation in patients with pneumoperitoneum.
BJA

hal-00689758
https://hal.archives-ouvertes.fr/hal-00689758
DOI : 10.1093/bja/aem166
PUBMED : 17626027

Éditeur(s) : HAL CCSD
Résumé : International audience
Up-to-date estimates of the health outcomes of preterm children are needed for assessing perinatal care, informing parents, making decisions about care, and providing evidence for clinical guidelines. To determine survival and neonatal morbidity of infants born from 22 through 34 completed weeks' gestation in France in 2011 and compare these outcomes with a comparable cohort in 1997. The EPIPAGE-2 study is a national, prospective, population-based cohort study conducted in all maternity and neonatal units in France in 2011. A total of 2205 births (stillbirths and live births) and terminations of pregnancy at 22 through 26 weeks' gestation, 3257 at 27 through 31 weeks, and 1234 at 32 through 34 weeks were studied. Cohort data were collected from January 1 through December 31, 1997, and from March 28 through December 31, 2011. Analyses for 1997 were run for the entire year and then separately for April to December; the rates for survival and morbidities did not differ. Data are therefore presented for the whole year in 1997 and the 8-month and 6-month periods in 2011. Survival to discharge and survival without any of the following adverse outcomes: grade III or IV intraventricular hemorrhage, cystic periventricular leukomalacia, severe bronchopulmonary dysplasia, retinopathy of prematurity (stage 3 or higher), or necrotizing enterocolitis (stages 2-3). A total of 0.7% of infants born before 24 weeks' gestation survived to discharge: 31.2% of those born at 24 weeks, 59.1% at 25 weeks, and 75.3% at 26 weeks. Survival rates were 93.6% at 27 through 31 weeks and 98.9% at 32 through 34 weeks. Infants discharged home without severe neonatal morbidity represented 0% at 23 weeks, 11.6% at 24 weeks, 30.0% at 25 weeks, 47.5% at 26 weeks, 81.3% at 27 through 31 weeks, and 96.8% at 32 through 34 weeks. Compared with 1997, the proportion of infants surviving without severe morbidity in 2011 increased by 14.4% (P < .001) at 25 through 29 weeks and 6% (P < .001) at 30 through 31 weeks but did not change appreciably for those born at less than 25 weeks. The rates of antenatal corticosteroid use, induced preterm deliveries, cesarean deliveries, and surfactant use increased significantly in all gestational-age groups, except at 22 through 23 weeks. The substantial improvement in survival in France for newborns born at 25 through 31 weeks' gestation was accompanied by an important reduction in severe morbidity, but survival remained rare before 25 weeks. Although improvement in survival at extremely low gestational age may be possible, its effect on long-term outcomes requires further studies. The long-term results of the EPIPAGE-2 study will be informative in this regard.
ISSN: 2168-6211

hal-01258705
http://hal.univ-brest.fr/hal-01258705
PUBMED : 25621457
DOI : 10.1001/jamapediatrics.2014.3351

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Ethnopharmacological relevancePsidium acutangulum Mart. ex DC is a small tree used by the Wayana Amerindians from the Upper-Maroni in French Guiana for the treatment of malaria.Aim of the studyIn a previous study, we highlighted the in vitro antiplasmodial, antioxidant and anti-inflammatory potential of the traditional decoction of P. acutangulum aerial parts. Our goal was then to investigate on the origin of the biological activity of the traditional remedy, and eventually characterize active constituents.Materials and methodsLiquid-liquid extractions were performed on the decoction, and the antiplasmodial activity evaluated against chloroquine-resistant FcB1 ([3H]-hypoxanthine bioassay) and 7G8 (pLDH bioassay) P. falciparum strains, and on a chloroquine sensitive NF54 ([3H]-hypoxanthine bioassay) P. falciparum strain. The ethyl acetate fraction (D) was active and underwent bioguided fractionation. All the isolated compounds were tested on P. falciparum FcB1 strain. In vitro anti-inflammatory activity (IL-1β, IL-6, IL-8, TNFα) of the ethyl acetate fraction and of an anti-Plasmodium active compound, was concurrently assessed on LPS-stimulated human PBMC and NO secretion inhibition was measured on LPS stimulated RAW murine macrophages. Cytotoxicity of the fractions and pure compounds was measured on VERO cells, L6 mammalian cells, PBMCs, and RAW cells.ResultsFractionation of the ethyl acetate soluble fraction (IC50 ranging from 3.4 to <1 µg/mL depending on the parasite strain) led to the isolation of six pure compounds: catechin and five glycosylated quercetin derivatives. These compounds have never been isolated from this plant species. Two of these compounds (wayanin and guaijaverin) were found to be moderately active against P. falciparum FcB1 in vitro (IC50 5.5 and 6.9 µM respectively). We proposed the name wayanin during public meetings organized in June 2015 in the Upper-Maroni villages, in homage to the medicinal knowledge of the Wayana population. At 50 µg/mL, the ethyl acetate fraction (D) significantly inhibited IL-1β secretion (−46%) and NO production (−21%), as previously observed for the decoction. The effects of D and guiajaverin (4) on the secretion of other cytokines or NO production were not significant.ConclusionsThe confirmed antiplasmodial activity of the ethyl acetate soluble fraction of the decoction and of the isolated compounds support the previous results obtained on the P. acutangulum decoction. The antiplasmodial activity might be due to a mixture of moderately active non-toxic flavonoids. The anti-inflammatory activities were less marked for ethyl acetate fraction (D) than for the decoction.
ISSN: 0378-8741

hal-01313006
http://hal.upmc.fr/hal-01313006
http://hal.upmc.fr/hal-01313006/document
http://hal.upmc.fr/hal-01313006/file/Houel_Wayanin_and.pdf
DOI : 10.1016/j.jep.2016.04.053

Résumé : Favorisées par les gouvernants en quête d’un nouveau modèle post-industriel, les économies basées sur la connaissance vont devenir en quelques décennies le référentiel à atteindre pour le développement de territoires soumis aux pressions de la globalisation.Longtemps considérés comme des éléments indispensables à la production et à la transmission du savoir, les établissements d’enseignement supérieur et de recherche, comme les universités, ont été de plus en plus intégrés dans les analyses sur le développement territorial à mesure que s’imposait le paradigme américain de la valorisation des activités de la recherche publique. Cette nouvelle mission imposée aux établissements de recherche, suppose qu’ils sont des facteurs d’un développement localisé. Mais le rôle qui leur est assigné est-il justifié ? À travers l’impact singulier de la recherche publique, on peut analyser la place de ces établissements sur leur territoire d’accueil. Apres avoir fait un état de l’art en matière d’analyse d’impact nous utilisons le cadre méthodologique de l’étude d’un cas illustrant cette problématique. L’agglomération de Brest mise sur la forte concentration d’établissements de recherche à vocation maritime pour développer le cluster local. Bien que non généralisable, ce cas éclaire les recherches dans ce domaine. Au-delà, la thèse apporte une autre vision sur les réformes de type top down des systèmes d’enseignement supérieur et de recherche considérant le savoir comme n’importe quel bien économique. Or la connaissance n’est pas un bien comme les autres. Et c’est cette singularité qui explique les difficultés d’analyse dans le champ de l’économie de la connaissance.
Promoted by governments seeking for a new post-industrial model, the knowledge-based economies will become in a few decades the repository to reach for the development of territories subject to the pressures of globalization. Regarded as essential to the production and transmission of knowledge, higher education and research institutions, such as universities, have been increasingly integrated into the analysis of territorial development while was emerging the american paradigm for valorisation of public research activities. This new mission imposed on research institutions, assume they are factors of localized development. Is this assigned role justified? Through the singular impact of public research, we can analyze the role of these institutions on their home territory. After a state of the art on the impact assessments, we developed a methodological framework for case study illustrating this problem. In the agglomeration of Brest, there is a high concentration of research institutions with maritime vocation on which rely the local cluster. Although not generalizable, this case enlightens the research in this domain. In addition, the thesis sheds new light on the top-down reforms of higher education and research systems considering knowledge as any economic good. But knowledge is not a commodity like others. And that would explain the difficulties of analysis in the field of the knowledge economy.

http://www.theses.fr/2014AGUY0807/document