Éditeur(s) : HAL CCSD
Résumé : In 1996 the European Commission Humanitarian Office (ECHO) launched a regional approach for disaster preparedness, focusing in its first phase on Central America, Caribbean and Southeast Asia (including Bangladesh). The first step in this process was the preparation of a «diagnostic study» that involved a situation review of the countries in these regions with regard to their vulnerabilities, disaster preparedness capacities and national plans or policies for disaster management.The Centre for Research on the Epidemiology of Disasters of the Université Catholique de Louvain (UCL) served as ECHO’s principal technical support with the collaboration of other institutions in Europe and the regions.The present «diagnostic report», covering Central America and the Caribbean, has been carried out by the Centre International pour la Formation et les Echanges en Géosciences (CIFEG) under the supervision of Professor Robert D’Ercole (Université de Savoie, Chambéry).Mr. Thierry Lesales (Université des Antilles et de la Guyane) participated closely in the drafting of this report and was actively involved in the field missions with Mr D’Ercole where they met and interviewed numerous national officials, non-governmental organisations and regional and international bodies. Further assistance was provided by Claudine Misson (CRED) for the interviews and information collected in the Dominican Republic. The report also draws from an earlier mission undertaken by Dr. Philippe Masure (BRGM, France), Christian Bugnion (CRED) and Alexandra Angulo (CRED) who undertook some of the preparatory work for the diagnostic study.This report presents an analysis of the disaster preparedness situation in Central America and the Caribbean and provides some preliminary recommendations regarding priorities and future programme direction. As such it remains primarily a descriptive study. It is expected to form the basis for the formulation of the ECHO Disaster Preparedness Action Plan.
En 1996, la Oficina Humanitaria de la Comunidad Europea (ECHO) lanzó la iniciativa de un enfoque regional en materia de preparación a los desastres, concentrándose inicialmente en las regiones de América Central, Caribe y Asia del Sureste (incluyendo a Bangladesh). La primera fase de este proceso fue la preparación de un « diagnóstico» que implicaba un examen de la situación de los países de cada una de estas regiones en relación a la vulnerabilidad, la capacidad de preparación a los desastres y las políticas y planes nacionales en materia de gestión de desastres.El Centre for Research on the Epidemiology of Disasters (CRED), de la Université Catholique de Louvain (UCL), ha sido el principal apoyo técnico de ECHO para esta iniciativa, con la colaboración y asistencia de otras instituciones en Europa y en las regiones arriba mencionadasEl presente informe que cubre América Central y el Caribe, fue realizado por el International Centre for Training and Exchanges in Geosciences (CIFEG), bajo la dirección del Profesor Robert D'Ercole (Université de Savoie).Thierry Lesales (Université des Antilles et de la Guyane) participó de cerca a la realización de este documento y estuvo activamente implicado junto al Profesor D'Ercole en las misiones que se realizaron en varios países. En el curso de estas misiones, se entrevistaron con numerosos representantes de gobiernos nacionales, de ONGs y de organizaciones regionales e internacionales Se contó igualmente con la asistencia de Claudine Misson (CRED), quien realizó la misión en República Dominicana. El informe se basa igualmente en una misión anterior llevada a cabo por Philippe Masure (BRGM, France), Alexandra Angulo (CRED) y Christian Bugnion (CRED), la cual realizó parte del trabajo preparatorio para el diagnóstico.El informe presenta un análisis de la situación en América Central y el Caribe y provee recomendaciones preliminares para las prioridades y dirección del futuro programa. En el marco de la segunda fase, está destinado a servir de base para la formulación del Plan de Acción de Preparación a los Desastres de ECHO.
Depuis 1994, ECHO (Office Humanitaire de la Commission Européenne, devenu le service de la Commission européenne à l’aide humanitaire et à la protection civile) a financé, à l'échelle mondiale, de nombreuses opérations pour la prévention et la préparation aux catastrophes (catastrophes naturelles principalement) Ces financements ont répondu aux demandes d'ONG et d'organisations internationales qui ont-elles-mêmes mis en oeuvre les projets correspondants. Les évaluations de ces opérations ont donné des appréciations positives. Cependant, ECHO souhaite s'impliquer davantage dans la prévention et la préparation aux catastrophes et mieux cibler ses actions pour une plus grande cohérence d'ensemble.Au cours de la réunion du 16 juillet 1996, le Comité d'Aide Humanitaire a approuvé la nouvelle approche régionale proposée par ECHO pour son programme de prévention, d'atténuation et de préparation aux catastrophes, le DIPECHO (Dlsaster Preparedness ECHO), pour la période 1996—1998. Ce programme doit s'appliquer dans un cadre régional en concentrant d'abord ses financements sur des plans d'action dans les Caraïbes, en Amérique Centrale, en Asie du Sud-Est et au Bangladesh. Par ailleurs, au lieu de répondre exclusivement aux demandes de financements spécifiques d'ONG, d'organisations internationales et de gouvernements, ECHO souhaite préparer des plans d'action et déterminer les partenaires les plus appropriés pour une mise en oeuvre dirigée par ECHO même. En outre, le DIPECHO a pour objet de rendre plus efficace l'action de l'ensemble de l'Union Européenne, par une étroite coordination de son action avec celles de la Commission et des Etats Membres. Il est enfin prévu de faire précéder la préparation des plans d'action par une phase de diagnostic au cours de laquelle seront identifiés, pour chaque région, les risques, les structures et politiques de prévention existantes aux niveaux communautaire, national et régional, ainsi que les appuis extérieurs en cours et à venir. L'objectif est non seulement de déterminer les lacunes, mais également d'évaluer la cohérence et l'efficacité des systèmes de réponse dans leur ensemble......Dans ce contexte, une première mission exploratoire a été réalisée du 30 septembre au 12 octobre 1996 dans les Caraïbes et l'Amérique Centrale (quatre pays visités) et a débouché sur un premier rapport (A. Angulo, Ch. Bugnion, Ph. Masure, "Rapport de mission exploratoire dans les Caraïbes ct en Amérique Centrale pour DIPECHO").Ce rapport apporte de nombreuses informations et en particulier:(1) il définit le cadre conceptuel, insistant, à juste titre, sur le fait que la prévention et la préparation doivent être distinguées de l'aide d'urgence et qu'elles font partie d'un processus continu au même titre que le développement ;(2) il présente les principales organisations régionales et internationales, et leurs activités dans le domaine de la prévention et de la préparation;(3) il met en évidence les grands types de besoins et fournit les premières orientations pour le programme DIPECHO......Le présent rapport, constituant le diagnostic proprement dit, fait suite à une deuxième série de missions effectuées dans la même région. Il vise à compléter les apports de la mission exploratoire, notamment par:(a) une analyse des catastrophes et de leurs conséquences:(b) une évaluation comparée des risques dans la région;(c) une analyse détaillée des réalisations et des besoins en matière de réduction des risques et des conséquences des catastrophes naturelles ;(d) un examen des conditions actuelles pour un programme DIPECHO cohérent, réalisable et efficace, avec, en particulier, la prise en compte de l’organisation actuelle de la prévention et de la préparation dans la région et un état des appuis extérieurs ;- des propositions de lignes d'actions prioritaires pour le DIPECHO......Le diagnostic s'est appuyé sur une importante documentation : travaux scientifiques, études et rapports recueillis auprès du CRED-Université Catholique de Louvain, du CIFEG, du DHA, de l’IDNDR, de divers organismes sur le terrain (notamment le centre de documentation de San José au Costa Rica), et d'universités européennes (Université de Savoie. Chambéry, Université de Lausanne). Mais ce sont avant tout les nombreux entretiens menés lors des missions (près de 200) qui ont donné corps au diagnostic.Treize pays Ont été visités entre le 22/01 et le 07/03/1997 :- République Dominicaine (C Misson);- Costa Rica, Guatemala, Nicaragua et Cuba (R. D'Ercole) ;- Antigua, Barbade, Haïti, Jamaïque, Ste-Lucie, St-Maarten, St-Vincent et le Guyana (Th. Lesales).Leur choix a été déterminé en concertation avec ECHO, le CRED-UCL et le CIFEG. Ils ne recouvrent pas l'ensemble des pays qu'il aurait été théoriquement possible de visiter. Cependant, le choix de pays-clés, les contacts établis avec de nombreux organismes de portée régionale et la documentation consultée, ont permis de bâtir un diagnostic d'ensemble......L'étude comporte trois parties.La 1e partie constitue une analyse des catastrophes en termes de bilan et de risque. Il s'agit, à l'aide de cartes, notamment, de montrer les effets des catastrophes naturelles en Amérique Centrale et dans les Caraïbes, de présenter la répartition et la fréquence des aléas naturels et de procéder à une analyse de critères de vulnérabilité. L'objectif est, enfin, de déterminer des niveaux de risque, à l'échelle de la région, compte tenu des dangers naturels et des critères de vulnérabilité.La 2° partie est l'étude des actions entreprises dans la région, ces dernières années, afin de réduire les risques et les conséquences des catastrophes. Cette étude permet de dégager des lacunes et des besoins. Les différentes composantes entrant dans le processus de réduction des catastrophes sont retenues : recherche scientifique et technique, prévention stricto sensu, préparation, information / formation. L'accent est également placé sur les modes actuels d'application des politiques de réduction des risques : de l'approche sectorielle à l'approche intégrée.La 3e partie traite des conditions actuelles pour la mise en oeuvre d'un programme DIPECHO cohérent et efficace. Quatre aspects fondamentaux sont analysés: les particularités régionales et nationales (l'hétérogénéité et ses conséquences); les faiblesses et qualités institutionnelles aux différents échelons géographiques: les caractéristiques des organismes susceptibles de contribuer à la mise en oeuvre du DIPECHO; le rôle actuel et en perspective de la Communauté Européenne et des Etats Membres.Chaque partie comporte une conclusion partielle La conclusion générale reprend les idées force des conclusions intermédiaires ct débouche sur des lignes d'actions prioritaires recommandées pour le DIPECHO......L'étude confiée au CIFEG par le CRED-UCL et ECHO a été coordonnée par Robert D'Ercole (Département de Géographie, Université de Savoie, Chambéry, France). Elle a bénéficié de la collaboration de Thierry Lesales (Département de Géographie, Université des Antilles et de la Guyane, Martinique, France) et de Patrick Pigeon (Département de Géographie, Université de Savoie, Chambéry, France). Ont également contribué à la réalisation de celle étude: Claudine Misson (CRED-UCL, Belgique), Jean-Claude Napias (CIFEG, directeur), Jacques Giri (CIFEG, président), Sylvie Orlyk (CIFEG, secrétariat).
https://hal.archives-ouvertes.fr/hal-01196496

hal-01196496
https://hal.archives-ouvertes.fr/hal-01196496
https://hal.archives-ouvertes.fr/hal-01196496/document
https://hal.archives-ouvertes.fr/hal-01196496/file/D%27Ercole%20et%20al%201997%20Diagnostic%20DIPECHO%20Caraibes%20compressed.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Given a graph, its hyperbolicity is a measure of how close its distance distribution is to the one of a tree. This parameter has gained recent attention in the analysis of some graph algorithms and the classification of complex networks. We study on practical improvements for the computation of hyperbolicity in large graphs. Precisely, we investigate on relations between the hyperbolicity of a graph G and the hyperbolicity of its atoms, that are the subgraphs output by the clique-decomposition invented by Tarjan [51, 65]. We prove that the maximum hyperbolicity taken over the atoms is at most one unit off from the hyperbol-icity of G and the bound is sharp. We also give an algorithm to slightly modify the atoms, called the " substitution method " , which is at no extra cost than computing the clique-decomposition, and so that the maximum hyperbolicity taken over the resulting graphs is exactly the hyperbolicity of the input graph G. An experimental evaluation of our method for computing the hyperbolicity of a given graph from its atoms is provided for collaboration networks and biological networks. Finally, on a more theoretical side, we deduce from our results the first linear-time algorithm for computing the hyperbolicity of an outerplanar graph.
ISSN: 0304-3975

hal-01540756
https://hal.inria.fr/hal-01540756
https://hal.inria.fr/hal-01540756/document
https://hal.inria.fr/hal-01540756/file/CCDL-2017.pdf
DOI : 10.1016/j.tcs.2017.06.001

Éditeur(s) : HAL CCSD Geological Society of America
Résumé : International audience
The post-rift denudation history of high-elevation divergent continental margins is central to deciphering source-to-sink systems across such margins and to unraveling their topographic evolution. We performed 40Ar-39Ar dating of supergene K-Mn oxides from supergene manganese ore deposits in order to constrain the age of in situ formed laterites on both the lowland and highland sides of the Western Ghats Escarpment of Peninsular India. Documentation of laterites as old as 53 Ma on the highland and 47 Ma at the foot of the escarpment shows that the escarpment stabilized before 47 Ma (possibly 60 Ma). The topographic setting of the dated weathering mantles also constrains denudation of the lowland and the highland since ca. 50 Ma to maximums of 5 m/m.y. and 15 m/m.y., respectively. Our results challenge denudation rates derived from apatite fission track thermochronology by documenting the topography and relief longevity of the southwest Indian margin and its hinterland. The results preclude large-magnitude uplift of Peninsular India after the Eocene, and more generally argue against late Neogene uplift and topographic rejuvenation of continental shields.
ISSN: 0091-7613

hal-01306559
https://hal.archives-ouvertes.fr/hal-01306559
DOI : 10.1130/G37303.1

Éditeur(s) : HAL CCSD Dipartamento di Scienze della Terra, Università degli Studi di Modena
Résumé : International audience
The aim or this paper is to give an overall view of the natural hazards and risks affecting the French West Indies. These are mainly connected with hurricanes, volcanic eruptions and earthquakes which have caused several deaths and seriously weakened the local economy during the last three centuries. First of all the geological and geographical conditions which determine the natural predisposition of the French West Indies to geophysical and atmospheric hazards are described. Then the risk for the population is taken into account, both in terms of' the direct effects of the above mentioned hazards and of the side-effects, that is tidal waves, floods and mass movements. Finally the economic and social impact of natural disasters on the French West Indies and the difficulties arising in risk mitigation are shown.
Lo scopo di questo lavoro è di fornire un quadro generale dei rischi naturali che interessano le Antille Francese. Questi sono principalmente connessi con uragani, eruzioni vulcaniche e terremoti che, nel corso degli ultirni tre secoli hanno causato parecchi decessi e seriamente indebolito la economia locale. Vengono dapprima descritte le condizioni geologiche e geografiche che determinano la naturale predisposizione delle Antille Francese a minacche di tipo sia endogeno che esogeno. Viene poi considerato il rischio per la.popolazione, sia in termiini di effetti diretti dei fenomeni sopra citati che in termini di effetti marginali dovuti allo sviluppo di marernotti, alluvioni e frane. Infine viene considerato l’impatto sul tessuto sociale ed economico dei disastri di origine naturale nelle Antille Francese e le difficoltà che insorgono nella mitigazione del rischio.
The Erasmus 93-94 Programme in Geomorphology : Intensive Course in the French Antilles and Student Mobility

Droits : info:eu-repo/semantics/OpenAccess
ISBN : 88-900094-0-3
hal-01191892
https://hal.archives-ouvertes.fr/hal-01191892
https://hal.archives-ouvertes.fr/hal-01191892/document
https://hal.archives-ouvertes.fr/hal-01191892/file/D%27Ercole%201995%20-%20Natural%20hazards%20in%20the%20French%20West%20Indies.pdf

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : En Haïti, rien ne semble être planifié et pensé sur le long terme, raison sans doute pour laquelle l’entrepreneuriat ne joue pas un rôle prépondérant dans le développement de l’économie du pays (Financial Times, 2015). Cette vision sur le court terme qui est celle de la majorité de la population -à savoir les pauvres- n’est cependant pas une vérité absolue puisque le groupe largement minoritaire de la population, les riches ou encore l’élite économique, compte des entrepreneurs au sens des pays riches, c'est-à-dire des personnes ayant une vision de l’entreprise sur le long terme avec pour perspective la croissance de l’entreprise et l’enrichissement personnel, parfois « saupoudré » ,ici et là, d’une touche sociale par rapport à la montée en puissance du phénomène Responsabilité Sociale des Entreprises (RSE). Ce numéro spécial sur l’entrepreneuriat en Haïti se veut force de propositions (pratiques) pour que l’entrepreneuriat ait droit de cité comme force motrice du développement d’Haïti. Si comme le dit l’entrepreneur Jerry Tardieu : investir et s’investir en Haïti est un acte de foi, que faire pour faire pour que l’entrepreneuriat soit un moteur de développement durable en Haïti ? Telle est la question centrale de ce numéro spécial. L’entrepreneuriat en Haïti a longtemps été marqué – notamment dans la partie formelle – par la dominance du commerce opéré pour une large part par des immigrés moyen-orientaux (Syriens, Libanais, etc.) et de grandes entreprises étatiques. L’économie haïtienne a entamé depuis les trois dernières décennies un élargissement de son entrepreneuriat à travers la privatisation des monopoles d’Etat et, récemment, se précise l’engouement des jeunes pour la création d’entreprises. Si pour certains analystes comme Lundahl (2010), l’entrepreneuriat communautaire a échoué en Haïti, il n’en demeure pas moins que la micro finance a connu un développement tel, qu’elle a démocratisé l’accès au financement et permis le développement d’une multitude de micro-entreprises (Paul, Daméus & Garrabé, 2011). In Haiti, nothing seems to be planned in advance. Everything seems to happen by chance, hence the reason why entrepreneurship is a heavy weight in the GDP of the country (Financial Times, 2015). This non strategic and short term vision of entrepreneurship in Haiti is peculiar to the vast majority of the population, that is to say the poor. However, this does not happen across the board as the rich (the minority of population) also called the ‘elite’ have a perception of entrepreneurship similar to developed countries where entrepreneurship is seen as a long term strategy with so called Corporate Social Responsibilities (CSR). This special issue about Haiti is to find practical solutions to ensure that entrepreneurship can play a major role in the economic development of the country. Jerry Tardieu, a Haitian entrepreneur, claimed that investing in Haiti is a proof of faith in the country’s potential. What can be done to turn entrepreneurship into a sustainable tool for the development of Haiti? This is the central research question of this special issue. For a while, leading entrepreneurs in Haiti were from the Middle East (Syria, Liban, etc) and public companies. However, over the last three years, entrepreneurs in Haiti have come from different backgrounds. Also, more and more young people are getting into entrepreneurship and many public companies have been privatised. Despite the fact that for some analyst’s entrepreneurship in Haiti has totally failed (Lundahl, 2010), the development of micro finance over the last few years has democratized access to funding, enabling development of a multitude of micro-enterprises (Paul & Dameus Garrabé, 2011) (Paul, Daméus & Garrabé, 2011). En Haití, nada parece estar planificado y pensado en el largo plazo, probablemente es la razón por la cual la iniciativa empresarial no está jugando un papel importante en el desarrollo de la economía (Financial Times, 2015). Esta visión a corto plazo es el de la mayoría de la población. Sin embargo, no es una verdad absoluta ya que el grupo de población en gran minoría, los ricos o la élite económica, los empresarios responsables de los efectos de los países ricos es decir, las personas con una visión de negocio a largo plazo con la perspectiva del crecimiento de la empresa y de enriquecimiento personal, aunque a veces 'salpicado aquí y allá de un toque social, en comparación con el aumento del fenómeno de la Responsabilidad Social Corporativa (RSC). Este número especial sobre el emprendimiento en Haití quiere suscitar propuestas (prácticas) para que la iniciativa empresarial llega a ser citada como una fuerza impulsora en el desarrollo de Haití. Si, como lo dice el empresario Jerry Tardieu, invertirse e invertir en Haití es un acto de fe, ¿que hacer para que el espíritu empresarial sea un motor para el desarrollo sostenible en Haití? Esta es la pregunta central de este número especial. Emprendimiento en Haití durante mucho tiempo ha sido etiquetado - sobre todo en la parte formal - por el predominio del comercio operado en gran parte por inmigrantes de Oriente Medio (Siria, Líbano, etc.) y las grandes empresas estatales. La economía haitiana ha comenzado las últimas tres décadas la expansión de la iniciativa empresarial a través de su privatización de los monopolios estatales y, desde hace poco, la moda de los jóvenes emprendedores. Aunque segun algunos analistas como Lundahl (2010), el emprendimiento comunitario no sucede Haití, el hecho es que las microfinanzas ha experimentado un desarrollo tal, se ha democratizado el acceso a la financiación, como permite el desarrollo de una multitud de microempresas (Paul & Dameus Garrabé, 2011).

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.9541
http://journals.openedition.org/etudescaribeennes/9541

Éditeur(s) : Wiley-blackwell Publishing, Inc
Résumé : We present the results from processing and interpreting five lines from the 1992 Erable multichannel seismic reflection experiment extending from the southeastern margin of Flemish Cap into the northern Newfoundland Basin. These profiles reveal significant along strike variations in the rifting styles experienced by Flemish Cap. In the southwest, a 100-km-wide transition zone is identified between thinned continental crust and thin oceanic crust. Similar to the conjugate Galicia Bank and Iberian margins, this transition zone contains a section of deep basement adjacent to a series of shallower ridges and is interpreted as exhumed serpentinized mantle. Along strike towards the northeast, this transition zone pinches out completely within 100 km and is replaced by thin oceanic crust directly adjacent to thinned continental crust. By interpreting nearby seismic profiles and profiles on the conjugate margins using the same classification criteria, we construct regional maps of the distribution of crustal domains on both sides of the North Atlantic. These maps reveal significant variations in rifting style on the conjugate margins and along strike of each margin and also highlight the role of ancient transfer zones in compartmentalizing these rifting variations into four distinct regions. We propose that the limited localization of shallow topographically high serpentinized peridotite ridges on the Newfoundland-Iberia and Flemish Cap-Galicia Bank conjugate margins, was directly related to an increase in the rate of extension following the separation of Flemish Cap and Galicia Bank which exhumed deeper, less serpentinized mantle.
Geophysical Journal International (0956-540X) (Wiley-blackwell Publishing, Inc), 2010-03 , Vol. 180 , N. 3 , P. 976-U4

Droits : 2010 RAS
http://archimer.ifremer.fr/doc/00001/11202/7876.pdf
DOI:10.1111/j.1365-246X.2009.04477.x
http://archimer.ifremer.fr/doc/00001/11202/

Éditeur(s) : HAL CCSD GERFLINT
Résumé : International audience
The evolution of Official French Certifications in French for Foreigners, DELF and DALF, offers an interesting statistical reference to understand, at least, on one side, the situation of French in Mexico. Among norms and social representations, DELF and DALF bring us a special look about the status of this language, from social aspirations to the impact they create on the learning and on the teaching process.
La evolución de las certificaciones oficiales del ministerio francés de Educación en francés como lengua extranjera, el DELF y el DALF, constituyen una referencia estadística interesante para entender, al menos en parte, la situación del francés en México. Entre tendencias normativas y valorización social, estas certificaciones permiten arrojar una mirada original sobre el estatus de esta lengua, desde las demandas sociales que motivan hasta el impacto que implican sobre el proceso de aprendizaje y enseñanza.
L’évolution des certifications officielles du ministère français de l’Éducation nationale en français langue étrangère, le DELF et le DALF, constitue une référence statistique intéressante pour appréhender, du moins en partie, la situation du français au Mexique. Entre tendances normatives et valorisation sociale, ces certifications permettent de dégager un regard original sur le statut de cette langue, des demandes sociales qui en motivent l’apprentissage à l’impact qu’elles induisent sur le processus d’apprentissage enseignement.
ISSN: 20074654

Droits : info:eu-repo/semantics/OpenAccess
halshs-01400353
https://halshs.archives-ouvertes.fr/halshs-01400353
https://halshs.archives-ouvertes.fr/halshs-01400353/document
https://halshs.archives-ouvertes.fr/halshs-01400353/file/Lenseignement_du_FLE_qu_Mexique_un_regar.pdf

Éditeur(s) : HAL CCSD American Geophysical Union (AGU)
Résumé : International audience
We decipher late-orogenic crustal flow characterized by feedback relations between partialmelting and deformation in the Variscan Montagne Noire gneiss dome. The dome shape and finite strainpattern of the Montagne Noire Axial Zone (MNAZ) result from the superimposition of three deformations(D1, D2 and D3). The early flat-lying S1 foliation is folded by D2 upright ENE-WSW folds and transposed in thecentral and southern part of the MNAZ into steep D2 high-strain zones consistent with D2 NW-SE horizontalshortening, in bulk contractional coaxial deformation regime that progressively evolved to noncoaxial dextraltranspression. The D2 event occurred under metamorphic conditions that culminated at 0.65 ± 0.05 GPa and 720± 20°C. Along the anatectic front S1 and S2 foliations are transposed into a flat-lying S3 foliation with top-to-NEand top-to-SW shearing in the NE and SW dome terminations, respectively. These structures define a D3 transitionzone related to vertical shortening during coaxial thinning with a preferential NE-SW to E-W directedstretching. Depending on structural level, the metamorphic conditions associated with D3 deformation rangefrom partial melting conditions in the dome core to subsolidus conditions above the D3 transition zone. Wesuggest that D2 and D3 deformation events were active at the same time and resulted from strain partitioningon both sides of the anatectic front that may correspond to a major rheological boundary within the crust.
ISSN: 0278-7407

hal-01208098
https://hal.archives-ouvertes.fr/hal-01208098

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Las religiones de origen africano han sido tomadas en Brasil, en Cuba y más recientemente en Venezuela como instrumento para incrementar la entrada de divisas, en programas de desarrollo del turismo presentados por las autoridades como sostenibles. Pero, tanto el control ejercido sobre ellas por los organismos oficiales, con fines de comercialización, como las rivalidades entre paises, así como en algún caso, entre ciudades de un mismo país, conllevan una enajenación de la cultura (según la teoría del control cultural de Guillermo Bonfill), cuestionando la posibilidad de un desarrollo equilibrado, es decir sostenible.
Les religions d’origine africaine ont été transformées, au Brésil, à Cuba et plus récemment au Venezuela, en instruments pour augmenter la captation de devises, par le biais de programmes présentés par les autorités comme répondant aux normes du développement durable. Mais, tant le contrôle exercé sur ces manifestations culturelles, à des fins de commercialisation, que les rivalités engendrées entre pays, ou entre villes dans certains cas, mènent à une aliénation des acteurs de leur propre culture (après Guillermo Bonfill), contredisant la définition même de “développement durable”.
The religions of African origin have been taken in Brazil, in Cuba and more recently in Venezuela as instruments to increase the inflow of currency, in tourism development programs presented by the authorities as sustainable. But the control exercised on them by the State organizations, with marketing purposes, as well as the rivalries between countries, as well as between cities of the same country in some cases, carry an alienation of the culture (according to Guillermo Bonfill's theory of cultural control), questioning the possibility of a balanced development, that is to say a sustainable development.
Brésil
Cuba
Venezuela

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.3852
http://journals.openedition.org/etudescaribeennes/3852

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Mechanism and kinematics of the Late Mesozoic continental extension event of eastern Asia are still debated. In order to better constrain its evolution, two granodioritic plutons of the Jiaodong Peninsula have been chosen as targets for a time-constrained palaeomagnetic study. Indeed, plutons are devoid of visible deformation, did not experience rotation along horizontal axis and are precisely dated by U/Pb and 40Ar/39Ar methods. Multidomain (MD) magnetite has been identified as the principal magnetic remanent carrier. The interpolation of existing and new U/Pb and 40Ar/39Ar ages revealed that characteristic remanent magnetisation was acquired in a narrow range of 116 ± 2 Ma. Twenty out of 27 sites present stable magnetic directions calculated from high-temperature or high-coercive components. The observations of the solo normal magnetic polarity for this palaeomagnetic collection and of the magnetic remanent age consistent with the Cretaceous Normal Superchron (CNS) argue that the characteristic magnetic remanence may be considered as primary. Detailed field observations of the intrusive relationship between the plutons and country rocks and Anisotropy of Magnetic Susceptibility (AMS) study reveal the absence of the subsequent deformation of plutons, or rigid rotation of plutons along a horizontal axis. Two palaeomagnetic poles have been therefore calculated from these plutons. Among 12 out 15 Cretaceous palaeomagnetic poles, including the two new poles provided by this study, from the Jiaodong Peninsula and on both sides of Tan-Lu and Muping-Jimo faults are statistically consistent. As a result, the Jiaodong Peninsula behaved as a rigid block as internal deformation appears negligible. The remaining three derived poles are probably due to the secular variation or/and the vicinity of fault zones near of the palaeomagnetic sampling site. Thus, they can not be applied to the peninsula-scaled tectonics. Comparison of these time52 constrained Cretaceous palaeomagnetic results of the Jiaodong Peninsula with those of North China Block (NCB) indicate that the Jiaodong Peninsula was rigidly attached to NCB since, 3 at least, the Cretaceous as residual difference is clearly insignificant with respect to the error brackets. These new palaeomagnetic results confirm that the relative clockwise (CW) rotation of Eastern Liaoning-Korea Block (ELKB) with respect to NCB does not affect the Jiaodong Peninsula as a rigid block, nevertheless, some tectonic structures have been reactivated since Cenozoic and local rotations could be produced. This palaeomagnetic study reveals that the Late Mesozoic extension in Eastern Asia is heterogeneously expressed in time and space. The complete understanding of the mechanism(s) of this extensional event needs further multidisciplinary investigations.
ISSN: 0031-9201

insu-00599546
https://hal-insu.archives-ouvertes.fr/insu-00599546
https://hal-insu.archives-ouvertes.fr/insu-00599546/document
https://hal-insu.archives-ouvertes.fr/insu-00599546/file/Charles_et_al_PEPI2011.pdf
DOI : 10.1016/j.pepi.2011.05.006

Éditeur(s) : HAL CCSD Czech Phycological Society
Résumé : International audience
As first observed on a group of taxa related to Cocconeis peltoides Hustedt, several other Cocconeis eHRenbeRG (Bacillariophyta) taxa possess a row of minute marginal pores on the external side of their sternum valve (SV) connected to small and simple internal portules, or processes. These processes are often located in continuity with the striae, but can also be slightly shifted or distant from the distal areola of the striae. The row of pores is often, but not always, externally separated from the stria by a crista marginalis. Within Cocconeis, and possibly all raphid diatoms, these processes seem unique and restricted to a few taxa. A list is presented of the taxa pertaining (or close) to Cocconeis that are actually known to share these micro–structures. In addition, the morphological variability of the processes is described in detail and a morphological comparison of the taxa is provided. The characteristic features of taxa showing a row of SV processes permit the tentative definition of several morphological groups. It is difficult to prove the taxonomic affiliation of these taxa and demonstrate or refute that these processes are ancestral characters. Some of these taxa are rare and restricted to low latitudes (e.g., tropical taxa) while others are frequent and ubiquitous. Abbreviations: (LM) light microscope, (SEM) scanning electron microscope, (RV) raphe valve, (SV) sternum valve, (RVVC) raphe valve valvocopula, (SVVC) sternum valve valvocopula
ISSN: 1802-5439

hal-01212883
https://hal-univ-perp.archives-ouvertes.fr/hal-01212883
https://hal-univ-perp.archives-ouvertes.fr/hal-01212883/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01212883/file/fottea_fot-201502-0003.pdf
DOI : 10.5507/fot.2015.015

Éditeur(s) : HAL CCSD Taylor & Francis (Routledge)
Résumé : International audience
Border areas are particular “hot spots” generating high levels of HIV vulnerability and facing great challenges to control epidemics. The objective of this study is to describe the sociodemographic, clinical and biological profiles of newly HIV diagnosed people at the French Guiana - Suriname border, to construct an HIV care cascade and compare it with the Surinamese one. HIV-patients aged over 15 years newly diagnosed in western French Guiana in 2011 and 2012 were included in a retrospective cohort study. Patients were identified using different sources (n=121). The male-to-female ratio was 0.8, 85% of the patients were of foreign origin, 72% were undocumented migrants, 21% were living in Suriname and 48% had baseline CD4 cell counts <200 cells/mm3. After one year, 34% were lost to follow-up, 54% received treatment, 34% had controlled viremia and 6% died. We observed a disappointing HIV cascade, like that of Suriname, requiring to develop a coordinated healthcare offer on both sides of the border. Targeted efforts through a bi-national collaboration are needed to address the specific issues of cross-border patients to reach the 90*3 UNAIDS’s diagnosis, link to care and treatment targets and better control the local epidemic
ISSN: 0954-0121

inserm-01476267
http://www.hal.inserm.fr/inserm-01476267
http://www.hal.inserm.fr/inserm-01476267/document
http://www.hal.inserm.fr/inserm-01476267/file/2017%20Jaries%20-%20Population%20movements%20and%20the%20HIV%20cascade-1.pdf
DOI : 10.1080/09540121.2017.1291899

Résumé : This paper aims to establish a comprehensive Iist of exotic species introduced into Atlantic French waters over the last century as well as their origin, and the vectors involved in the process. At least 104 non indigenous species have been recorded in the Atlantic and Channel coastal wa• ters. Among those species, only a few (Bonamia ostreae, Crepidula fornicata) have resulted in highly significant negative impacts and side-effects on the coastal activity. In contrast, the introduction of the Japanese oyster Crassostrea gigas can be considered to be successful, sustaining a large industry counting more than 4,000 companies and 150,000 tons of yearly production. Over the last decade, French and European laws have strenghtened the controls over exotic species introductions, limiting their impacts. These new regulations and increased awareness from the scientific community with regard to coastal industry and biodiversity have reduced significantly the cases of deliberate introduction, while the risk analysis requirement has improved the overall management. However, in spite of these improvements, cases remain significant, mostly by accidental and/or increased vectors of introduction such as the ballast waters and sediment. Moreover, global changes should now be considered as a major issue, Iikely inducing future geographic distribution changes over a large European coastal range. Understanding the invasion population dynamics for exotic species remains a challenging research issue currently addressed by the French INVABIO multidisciplinary program.
Invasive aquatic species of Europe. Distribution, impacts and management. E. Leppäkoski, S. Gollasch & S. Olernin (eds).

Droits : 2002 Kluwer Academie Publishers. Printed in the Netherlands.
https://w3.ifremer.fr/archimer/doc/00000/3100/

Éditeur(s) : HAL CCSD Oxford University Press (OUP)
Résumé : International audience
In places where sedimentation and erosion compete at fast rates, part of the record of past earthquakes on faults may be buried, hence hidden, in the first few metres below the surface. We developed a novel form of palaeoseismology, of geophysical type, based on the use of a dense pseudo-3-D Ground Penetrating Radar (GPR) survey to investigate such possible buried earthquake traces, on a long, fast-slipping strike-slip fault (Hope fault, New Zealand), at a site (Terako) where marked alluvial conditions prevail. We first used LiDAR data to analyse the ground surface morphology of the 2 km2 site at the greatest resolution. Nineteen morphological markers were observed, mainly alluvial terrace risers and small stream channels that are all dextrally offset by the fault by amounts ranging between 3 and 200 m. The measurements document about 10 past earthquake slip events with a mean coseismic slip of 3.3 +/- 1 m, with the most recent earthquake event having a slip of 3 +/- 0.5 m. We then investigated a detailed area of the site (400 x 600 m2) with pseudo-3-D GPR. We measured 56, similar to 400 m long, 510 m spaced GPR profiles (250 MHz), parallel to the fault and evenly distributed on either side. The analysis revealed the existence of a palaeosurface buried at about 3 m depth, corresponding to the top of alluvial terraces of different ages. That buried surface is incised by a dense network of stream channels that are all dextrally offset by the fault. We measured 48 lateral offsets in the buried channel network, more than twice than at the surface. These offsets range between 6 and 108 m, as observed at the surface, yet provide a more continuous record of the fault slip. The similarity of the successive slip increments suggests a slip per event averaging 4.4 +/- 1 m, fairly similar to that estimated from surface data. From the total surface and buried 67 offset collection, we infer that a minimum of 30 large earthquakes have broken the Hope fault at the Terako site in the last about 67 kyr, with an average coseismic slip of 3.2 +/- 1 m, a minimum average recurrence time of about 200 yr, and a magnitude of at least Mw 7.07.4. Our study therefore confirms that part of the record of past earthquakes may indeed reside in the first few metres below the surface, where it may be explored with geophysical, GPR-based palaeoseismology. Developing such a new palaeoseismological tool should provide rich information that may complement surface observations and help to document the past earthquakes on faults.
ISSN: 0956-540X

hal-00704560
https://hal.archives-ouvertes.fr/hal-00704560
DOI : 10.1111/j.1365-246X.2012.05366.x

Éditeur(s) : HAL CCSD
Résumé : The Firouzkuh Fault in most of its extension is located at the southern side of Firouzkuh Valley in west of the Central Alborz. It is a SW - NE prominent structure with a 70 km long on a sinistral -normal fault. It has been known as a south-dipping reverse fault.Paleoseismic analysis and C14 dating along the Firouzkuh left -lateral strike-slip fault indicate that Central Alborz has been shaken by large earthquakes during the Holocene. Here we present the data carried out of one of the two excavated trenches with 15 m long, 2m wide, ~ 4m deep in the east of Firouzkuh, where we found some evidence for last paleoearthquake associated to seismic re-activity on Firouzkuh Fault in the second trench (F2) that dug across a gauge zone. The last event is evidenced by cutting young superficial deposit where this faulted unit stratigrafically covered alluvium deposits yielded dated human bones fragments. The bones found in 60-70cm-deep of trench which a C14 age of 1159 ± 28 BP. Regarding to estimated slips per event on paleoseismological log of eastern wall of trench F1, event magnitudes for each paleoearthquakes are M≈7.
Geosciences Scientific Quarterly Journal

hal-00800375
https://hal.archives-ouvertes.fr/hal-00800375

Éditeur(s) : HAL CCSD Oxford University Press (OUP): Policy B - Oxford Open Option A
Résumé :  
The mechanism for tree orientation in angiosperms is based on the production of high tensile stress on the upper side of the inclined axis. In many species, the stress level is strongly related to the presence of a peculiar layer, called the G-layer, in the fibre cell wall. The structure of the G-layer has recently been described as a hydrogel thanks to N2 adsorption-desorption isotherms of supercritically dried samples showing a high mesoporosity (pores size from 2-50 nm). This led us to revisit the concept of the G-layer that had been, until now, only described from anatomical observation. Adsorption isotherms of both normal wood and tension wood have been measured on six tropical species. Measurements show that mesoporosity is high in tension wood with a typical thick G-layer while it is much less with a thinner G-layer, sometimes no more than normal wood. The mesoporosity of tension wood species without a G-layer is as low as in normal wood. Not depending on the amount of pores, the pore size distribution is always centred around 6-12 nm. These results suggest that, among species producing fibres with a G-layer, large structural differences of the G-layer exist between species.
Journal of Experimental Botany

hal-01032161
https://hal.archives-ouvertes.fr/hal-01032161
DOI : 10.1093/jxb/erp133

Éditeur(s) : Université des Antilles Études caribéennes
Résumé : Le débat théorique sur les migrations et la famille connait une ambivalence allant du postulat de la migration comme une logique « individualiste » et de distanciation de la famille à celui de la migration vue comme une stratégie de survie portée par le réseau familial. C’est dans le but de contribuer à ce débat que le présent texte aborde l’analyse du processus migratoire sous l’angle des stratégies déployées par les migrants « Hloua » de la côte béninoise. Quatre dimensions ont particulièrement retenu notre attention : la prise de décision, le financement et l’organisation du voyage, l'intégration dans le milieu d’accueil, et les rapports maintenus avec le milieu d'origine.L’analyse s’appuie sur les récits de migration collectés auprès de migrants de retour ou de membres de familles restés au village, ceci dans le cadre d’une enquête plus large sur la pauvreté et les stratégies de survie dans le milieu de la pêche artisanale (Avloh, Ayiguinnou et Agoué) au Bénin. Cette analyse de récit a été complétée par des analyses de type quantitatif sur la fréquence des recours pour l’organisation et la prise de décision, la fréquence de recours pour l’insertion résidentielle et professionnelle, et le montant des envois de fonds. Les résultats montrent la place centrale du réseau familial le long du processus migratoire depuis la prise de décision, l’organisation du voyage, le « confiage » de la femme et des enfants du migrant, à l’établissement résidentiel et l’insertion professionnelle dans le milieu d’accueil. Ce réseau organise et structure efficacement le phénomène migratoire en intervenant lors des étapes décisives. Cependant, une fois insérés, les rapports maintenus avec le réseau familial se limitent pour la plupart à une solidarité affective, caractérisée par des contacts téléphoniques ou transferts de message et quelques envois de fonds largement en deçà des attentes. Ce qui fait dire de plus en plus que le migrant diminue le capital social de la famille sans pour autant y contribuer de façon substantielle sur le plan financier : Un paradoxe qui pourrait bien trouver son explication dans les recherches futures sous une perspective dynamique des migrations.
The theoretical debate on migration and family is ambivalent. Migration can be seen from an “individualist’’ and distant logic of the family or, on the other hand, migration can be viewed as a strategy of survival for the family network. It is in the objective of contributing to this debate, the present article will analyze the migration process from a migrant strategy perspective, more specifically from the perspective of the “Hloua” migrants off the Benin coast. Four dimensions are of particular interest: the decision making process, the cost and organization of the trip, integration in the host community and the maintenance of relations with the host community. Within a large scale research on poverty and the strategies of survival of artisan fishing (Avloh, Ayiguinnou et Agoué) in Bénin, the present analysis is based on migration stories collected from returning migrants or from family members still living in the village. This story analysis has been completed with quantitative analyses on the frequency of the use of organization and decision making, the frequency of the use of residential and professional insertion, and the amount of remittances. The results show the central place of family ties during the migratory process from the start of the decision making process, the travel planning, the entrusting of the women and children of the migrant, to the residential establishment and the professional insertion in the host society. This network organizes and structures efficiently the migratory phenomenon by intervening during the decisive steps. However, once inserted, the connections maintained with the family network are limited for the majority to an affective solidarity characterized by telephone contacts or message transfers, and sometimes remittances sent back largely lower to the family’s expectations. This results more and more in the migrant diminishing the social capital of the family without always contributing in some substantially way on the financial side. A paradox which could find its explanation in future researches under a perspective of migrations’ dynamics.
Bénin

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.5785
http://journals.openedition.org/etudescaribeennes/5785

Éditeur(s) : HAL CCSD
Résumé : Croton urucurana Baillon (Euphorbiaceae), plant species popularly known in Brazil as “sangra-d’água”, is commonly found in Mato Grosso do Sul State (midwestern Brazil), where its latex is popularly used to treat several types of cancer. Despite the ethnopharmacological significance of the species, no phytochemical or cytotoxic studies of its latex have been published. In this context, the aim of the present study was to assess the cytotoxic activity of crude extracts, fractions and isolated compound from the latex of C. urucurana and to investigate the effects of crourorb A1 on the viability, apoptosis, cell cycle and cell migration of human hepatocarcinoma cell lines (Huh-7). Also, we have evaluated the viability of Huh-7 cells treated with crourorb A1 in 3D collagen gels. The cytotoxicity was detected using the sulforhodamine B (SRB) assay against six human cancer cells lines and one nontumor NIH/3T3 cell line (murine fibroblast). Studies on the mechanism of cell death of crourorb A1 were conducted in different test systems in vitro. The bioactive ethyl acetate phase obtained from the latex of C. urucurana afforded a novel cyclic peptide, [1−9-NαC]-crourorb A1, that proved active against NCIADR/ RES (ovary, multidrug-resistance phenotype) cells with the same potency as doxorubicin (positive control) and inactive up to the highest concentration tested against nontumor NIH/3T3 cells (GI50 = > 250 μg/mL). Crourorb A1 treatment decreases the cell viability of Huh-7 at dose and time dependent manner associated with induction of apoptosis by caspase 3/7 activation and increasing expression of pro-apoptotic proteins: Bak, Bid, Bax, Puma, Bim, and Bad and clived-caspase3 protein. The JNK/MAP pathway is involved in this induced cell death. Crourorb A1 effect is also associated with G2/M phase cell cycle arrest. In parallel, we observed that crourorb A1 treatment resulted in an increase of cyclin-dependent kinase (CDK1), cyclin B1 and cyclin D1 expressions. A significant reduction of Huh-7 cells migration by crourorb A1 can be assessed and we also show that cells grown on 3D collagen gels exhibited increased resistance to crourorb A1 when compared to 2D cell culture.
Croton urucurana Baillon (Euphorbiaceae), est une plante très connue et utilisée en médecine traditionnelle au Brésil, la «sangra-d’água» retrouvée dans l'État du Mato Grosso do Sul (région Centre-Ouest du Brésil). Son latex est abondamment utilisé en médecine traditionnelle dans le traitement de plusieurs types de cancer. En dépit de son importance ethnopharmacologique, on ne trouve aucune étude sur sa composition chimique ou sur sa potentielle activité anti-cancéreuse. L’objectif de ce travail a été d'évaluer l'activité cytotoxique des extraits totaux, fractions d’extraits et de molécules purifiées, isolées du latex de C. urucurana. Nous avons étudié plus particulièrement les effets du crourorb A1 sur la viabilité, l'apoptose, le cycle cellulaire et la migration de cellules issues de carcinome hépatocellulaire humaine (Huh-7). Nous avons également évalué l’effet du crourorb A1sur la viabilité des cellules Huh-7 cultivées dans les gels de collagène en 3D. L' activité cytotoxique ont été réalisées par le test à la sulforhodamine B sur six lignées cellulaire cancéreuses et sur une lignée cellulaire non cancéreuse de fibroblastes murins, les cellules NIH/3T3. L'étude phytochimique de la fraction ‘acétate d'éthyle’ du latex de C. urucurana bioguidé a permis d’obtenir un nouveau cyclopeptide que nous avons nommé [1-9-NαC]-crourorb A1. Le crourorb présente une cytotoxicité puissante sur la lignée cellulaire cancéreuse NCI-ADR/RES (ovaire, le phénotype de multirésistance) à un niveau équivalent à celle de la doxorubicine (témoin positif). Ce composé est de plus pratiquement inactif (GI50 = >250 μg/mL) sur la lignée non cancéreuse NIH/3T3. L'évaluation de la cytotoxicité in vitro du crourorb A1 (test wst1) sur les cellules Huh-7 a démontré que la viabilité des cellules est inhibée de manière dose et temps-dépendant. Nous avons mesuré une forte activation des caspases 3 et 7 et une nette augmentation de l’expression des protéines pro-apoptotiques (Bak, Bid, Bax, Puma, Bim et Bad) ainsi que de la caspase 3 clivée par le crourorb A1. Nous avons également déterminé que la voie de signalisation JNK-MAPkinase semble nécessaire à l’induction de la mort cellulaire des cellules Huh-7 traitées au crourorb A1. Le crourob A1 induit un arrêt du cycle cellulaire en phase G2/M. En parallèle, les expressions de la cycline-dépendante kinase CDK1, des cyclines B1 et D1 sont augmentées après traitement au crourorb A1. De plus, le crourorb A1 a un effet inhibiteur significatif de la migration des cellules Huh-7, en présence ou absence de mitomycine C. Nous avons également confirmé, l’effet inhibiteur du crourob A1 sur la viabilité des cellules Huh7 cultivées en 3D dans les gels de collagène 1 et démontré que les cellules cultivées en 3D semblent plus résistantes au crourorb A1 par rapport aux cultures en monocouche 2D.
Croton urucurana Baillon (Euphorbiaceae) é uma espécie arbórea conhecida popularmente no Brasil como “sangra d´água”, comumente encontrada no estado de Mato Grosso do Sul, onde seu látex tem sido utilizado na medicina popular no tratamento de vários tipos de câncer. Apesar de sua importância etnofarmacológica, não há relatos de estudos relacionados à sua composição química ou atividades anticâncer na literatura. Nesse contexto, o objetivo do presente estudo foi avaliar a atividade citotóxica de extratos, fases, frações e da substância isolada do látex de C. ururucurana e investigar os mecanismos celulares e moleculares in vitro responsáveis pela citotoxicidade da substância isolada considerando seu potencial apoptótico e influência sobre a progressão do ciclo celular em uma linhagem de hepatocarcinoma celular humano (Huh-7), bem como, os efeitos desta substância sobre a migração e viabilidade de células Huh-7 cultivadas em geis de colágeno em 3D. O ensaio de citotoxicidade in vitro foi realizado com o corante sulforrodamina B (SRB) em seis linhagens de células neoplásicas humanas e uma linhagem de células não neoplásicas NIH/3T3 (fibloblasto murinho). Os estudos de mecanismos de ação com crourorb A1 foram conduzidos em diferentes sistemas-teste in vitro. O estudo fitoquímico biomonitorado da fase bioativa acetato de etila do látex de C. urucurana resultou no isolamento de um novo ciclopeptídeo denominado [19-NαC]-crourorb A1, que apresentou potente atividade citotóxica frente à linhagem de células neoplásicas NCI-ADR/RES (ovário com fenótipo de resistência a múltiplos fármacos), com a mesma potência que a doxorrubicina (controle positivo), e foi inativa até a maior concentração testada (GI50 = >250 μg/mL) frente à linhagem de células não neoplásicas 3T3. A exposição de células Huh-7 ao crourorb A1 resultou em uma diminuição da viabilidade celular de maneira dose e tempo-dependentes. Nós observamos um aumento da atividade de caspases 3 e 7 e um aumento da expressão de proteínas próapoptóticas (Bak, Bid, Bax, Puma, Bim e Bad) e caspase 3 clivada após tratamento com crourorb A1. Além disso, observamos que a via de sinalização celular MAP/JNK foi necessária para induzir a morte celular em células Huh-7 tratadas com crourorb A1. Os efeitos de crourorb A1 foram também associados com o acúmulo de células na fase G2/M do ciclo celular. Em paralelo, as expressões da cinase dependente da ciclina (CDK1), ciclina B1 e ciclina D1 foram aumentadas após tratamento com crourorb A1. Foi demonstrado também o envolvimento de crourorb A1 na redução da migração de células Huh-7 cultivadas na presença e ausência de mitomicina C. A avaliação da viabilidade de células Huh-7 cultivadas em geis de colágeno em 3D apontou uma maior resistência destas células ao crourorb A1 quando comparadas com a cultura de células em 2D.
https://tel.archives-ouvertes.fr/tel-01478286

NNT : 2016REN1B010
tel-01478286
https://tel.archives-ouvertes.fr/tel-01478286
https://tel.archives-ouvertes.fr/tel-01478286/document
https://tel.archives-ouvertes.fr/tel-01478286/file/DE-MATOS-CANDIDO-BACANI-Priscila.pdf

Éditeur(s) : HAL CCSD
Résumé : International audience
The main biological function of reaction wood is to act as “muscle” for trees, enabling them to control their posture and right stems when they are permanently disturbed from their set-point inclination by gravity or winds. The key property to achieve this function is the development of high mechanical stress during the formation of reaction wood cells, called “maturation strains”. Moreover, this function is basically performed through the asymmetric formation of wood (in quantity or quality) around the tree circumference. This asymmetry enables stems to bend upward or to compensate for the downward bending induced by gravity, as an asymmetric force associated to maturation strains creates a bending moment (i.e. one side of the stem “pulls” the other one). We will discuss the traits (cross sectional size and shape, wood features as G fibers or microfibril angle, eccentric growth even in usual or extreme cases as buttresses, total biomass growth and height of center of mass, stem lean and set-point angle) involved to understand how the posture control works. We will give simple formulas to estimate a “muscle efficiency” from biomechanical modeling. We will give practical methods to estimate all the involved traits, especially maturation strains from direct and indirect measurements, in peripheral functional wood or by retrospective dendrochronological analysis. Then, we will illustrate how tree stem tropisms and especially gravitropism, widely studied by physiologists, are key processes in natural ecosystems, through practical examples from tropical rainforest tree communities and regeneration of European mixed beech forests. Using the previous definition of postural control efficiency, we will show that the cross section size is rapidly a limiting factor, opposing the extreme strategies of flexible small stems, which bend easily but also right themselves quickly, to stiff big stems. Lastly, as wood in living trees ensures general storage, defence, vascular and skeletal functions, we will ask general questions about synergies and trade-offs between posture control and other functions.
Botany 2014 : new frontiers in botany
Boise, United States

hal-01627031
https://hal.archives-ouvertes.fr/hal-01627031

Éditeur(s) : HAL CCSD Mineralogical Society of America
Résumé : International audience
Pressure-temperature divariant melting phase relations of model carbonated peridotite in the system CaO-MgO-Al2O3-SiO2-CO2 from 8 to 12 GPa are reported. From 8 to 12 GPa, melting temperatures on the studied pressure-temperature divariant surface rise quite rapidly. Liquids, in equilibrium with forsterite, orthopyroxene, clinopyroxene, and garnet, on the low-temperature side of the divariant surface are magnesiocarbonatitic in composition. With increasing temperature along an isobar on the pressure-temperature divariant surface, and with the same crystalline phase assemblage, liquids gradually become kimberlitic in their composition. Given the model system data reported here, Group IB kimberlites and perhaps some kimberlites from Greenland, Canada, and South Africa could be generated from direct melting of carbonated peridotite in the pressure range of approximately 6-8 GPa. Some kimberlites from Canada and Russia could have formed by partial melting of carbonated mantle peridotite at pressures of about 10-12 GPa. From 8 to 12 GPa, liquid compositions on the studied divariant surface show a limited compositional range, which implies that the divariant surface is essentially flat. The implied flatness of the divariant surface, and so long as the liquid is in equilibrium with the crystalline assemblage of forsterite + orthopyroxene + clinopyroxene + garnet on the divariant surface, indicate that kimberlites belonging to Group IA and those more magnesian than Group IA cannot have their origin in only being a melting product of carbonated mantle peridotite. The absence of topography of the studied pressure-temperature divariant surface in all likelihood limits the generation of kimberlites in the Earth's upper mantle only.
ISSN: 0003-004X

hal-01053915
https://hal.archives-ouvertes.fr/hal-01053915
DOI : 10.2138/am.2014.4826