Éditeur(s) : Université des Antilles Études caribéennes
Résumé : La République de Trinidad-et-Tobago, située à l’extrême sud de l’arc des Petites Antilles fait figure d’exception dans la région Caraïbe. En effet, l’économie de l’île dépend presque exclusivement du secteur industriel et gazier, alors que le tourisme et l’agriculture participent peu au produit intérieur brut du pays, au contraire des autres îles caribéennes. Profitant d’un contexte international favorable, Trinidad connaît depuis deux décennies une croissance économique continue qui lui permet d’afficher des indices sociaux élevés, mais son économie garde les caractéristiques d’un Petit État Insulaire en Développement et elle doit faire face à des problèmes persistants de chômage et de pauvreté. C’est dans ce contexte que le gouvernement a initié une politique de diversification économique identifiant plusieurs domaines d’intervention, dont le tourisme, susceptible de réduire la pauvreté. L’objectif de cette étude est d’analyser les impacts et les limites d’actions touristiques pro-pauvres dans un petit état insulaire au travers d’une expérience menée dans le village de Matura, au nord-est de Trinidad.
The Republic of Trinidad and Tobago, located in the extreme south of the Lesser Antilles, is an exception in the Caribbean region. Indeed, unlike other Caribbean islands, the economy of Trinidad and Tobago depends almost exclusively on industrial and gas sector, while tourism and agriculture involved a small share of gross domestic product of the country.Taking advantage of a favorable international context, Trinidad known for two decades continued economic growth that allows it to display high social indices, but its economy keeps the characteristics of a Small State Islander Developing and faces problems of unemployment and poverty. It’s in this context that the government has initiated a policy of economic diversification identifying several areas of activity, including tourism, likely to reduce poverty. The objective of this study is to analyze the impacts and limitations of pro-poor tourism actions in a small island state through an experiment conducted in the village of Matura in the Northeast of Trinidad.
Trinité

Droits : info:eu-repo/semantics/openAccess
urn:doi:10.4000/etudescaribeennes.6535
http://journals.openedition.org/etudescaribeennes/6535

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
In this study, we report new U-Pb zircon ages and amphibole and biotite 40Ar-39Ar cooling ages for igneous and metaigneous rocks from the eastern portion of the Borborema Province (NE Brazil). We combine these results with preliminary thermobarometric estimates and existing data to place constraints on the timing and duration of the Brasiliano-Pan-African Orogeny in northeastern Brazil and on the subsequent late- to post-orogenic history. The Alcantil orthogneiss contains a complex zircon population, but the youngest concordant analyses yielded an age of 632 ± 17 Ma (2σ). These grains have low Th/U ratios (<0.1), and the age of 632 Ma is therefore interpreted as dating the metamorphic event responsible for the acquisition of the gneissic fabric. In the Caruaru biotite amphibole orthogneiss, concordant analyses provided an age of 618 ± 4 Ma (2σ), which we relate to emplacement of the protolith of the Caruaru orthogneiss. Together with available U-Pb data from the literature, the 632-600 Ma age range is regarded as dating development of a regional flat-lying foliation coeval with high-grade metamorphism (upper amphibolite facies conditions). The 586 ± 3 Ma age (2σ) of the Panelas pluton is similar to those of other granitic plutons associated with a voluminous plutonism of high-K calc-alkaline to shoshonitic nature that occurred at 590-580 Ma. This plutonism slightly predated or was synchronous with development of large strike-slip shear zones. Amphibole grains yielded 40Ar-39Ar ages ranging from 584 ± 4 Ma to about 530 Ma, suggesting that regional temperatures remained near the closing temperature of this mineral (≈500 °C) for a long time. Most 40Ar-39Ar biotite ages range from 552 to 533 Ma, but two samples yielded plateau ages of 519 ± 5 Ma and 509 ± 5 Ma. The inferred rather slow cooling of the studied region possibly reflects low rates of unroofing, allowing persistence of a protracted thermal anomaly caused by the massive injection of magmas at the end of the Neoproterozoic.
ISSN: 0895-9811

hal-00745698
https://hal.archives-ouvertes.fr/hal-00745698
DOI : 10.1016/j.jsames.2012.06.003

Éditeur(s) : HAL CCSD American Society for Microbiology
Résumé : International audience
A number of men receiving prolonged suppressive HAART still shed HIV in semen. To investigate whether this seminal shedding may be due to poor drug penetration and/or viral production by long-lived cells within male genital tissues, we analyzed semen and reproductive tissues from macaques chronically infected with SIVmac251 submitted to HAART for 4 months, intensified over the last seven weeks with an integrase inhibitor. We showed that a subset of treated animals continued shedding SIV in semen despite efficient HAART. This shedding was not associated with low antiretroviral drug concentrations in semen, or in testis, epididymis, seminal vesicles and prostate. HAART had no significant impact on SIV RNA in the urethra, whereas it drastically reduced SIV RNA levels in the prostate and vas deferens, and to a lesser extent in the epididymis and seminal vesicle. The only detectable SIV RNA positive cells within the male genital tract after HAART were urethral macrophages. SIV DNA levels in genital tissues were not decreased by HAART, suggesting the presence throughout the male genital tract of non-productively infected cells. In conclusion, our results demonstrate that 4 months of HAART induced variable and limited control of viral infection in the male reproductive organs, particularly the urethra, and suggest that infected long-lived cells in the male genital tract may be involved in persistent seminal shedding during HAART. These results pave the way for further investigations of male genital organs infection in long term treated infected individuals. A substantial subset of men receiving prolonged suppressive HAART in the blood still harbor HIV in semen, and cases of sexual transmission have been reported. To understand the origin of this persistence, we analyzed the semen and male reproductive tissues from SIV-infected macaques treated by HAART. We demonstrated that persistent seminal shedding was not linked to poor drug penetration in semen or semen-producing prostate, seminal vesicle, epididymis and testis. We revealed that HAART decreased SIV RNA to various extents in all male genital organs, with the exception of the urethra, in which SIV RNA+ macrophages were observed despite HAART. Importantly also, HAART did not impact SIV DNA levels in the male genital organs. These results suggest that infection of male genital organs, and particularly the urethra, could be involved in the release of virus in semen during HAART.
ISSN: 0022-538X

hal-01139816
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01139816
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01139816/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01139816/file/Detection%20of%20SIV%20in%20Semen%2C%20Urethra%2C%20and%20Male%20Reproductive%20Organs%20during%20Efficient%20Highly%20Active%20Antiretroviral%20Therapy.pdf
PUBMEDCENTRAL : PMC4442442

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
Lateralization, i.e. the preferential use of one side of the body, may convey fitness benefits for organisms within rapidly-changing environments, by optimizing separate and parallel processing of different information between the two brain hemispheres. In coral reef-fishes, the movement of larvae from planktonic to reef environments (recruitment) represents a major life-history transition. This transition requires larvae to rapidly identify and respond to sensory cues to select a suitable habitat that facilitates survival and growth. This ‘recruitment’ is critical for population persistence and resilience. In aquarium experiments, larval Acanthurus triostegus preferentially used their right-eye to investigate a variety of visual stimuli. Despite this, when held in in situ cages with predators, those larvae that previously favored their left-eye exhibited higher survival. These results support the “brain’s right-hemisphere” theory, which predicts that the right-eye (i.e. left-hemisphere) is used to categorize stimuli while the left-eye (i.e. right-hemisphere) is used to inspect novel items and initiate rapid behavioral-responses. While these experiments confirm that being highly lateralized is ecologically advantageous, exposure to chlorpyrifos, a pesticide often inadvertently added to coral-reef waters, impaired visual-lateralization. This suggests that chemical pollutants could impair the brain function of larval fishes during a critical life-history transition, potentially impacting recruitment success.
ISSN: 2045-2322

Droits : http://creativecommons.org/licenses/by/
hal-01585550
http://hal.upmc.fr/hal-01585550
http://hal.upmc.fr/hal-01585550/document
http://hal.upmc.fr/hal-01585550/file/s41598-017-09381-0.pdf
DOI : 10.1038/s41598-017-09381-0

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
The emerging orbicular batfish (Platax orbicularis) aquaculture is the most important fish aquacultureindustry in French Polynesia. However, bacterial infections are causing severe mortality episodes.Therefore, there is an urgent need to find an effective management solution. Besides the supplyingdifficulty and high costs of veterinary drugs in French Polynesia, batfish aquaculture takes place close tothe coral reef, where use of synthetic persistent drugs should be restricted. Medicinal plants andbioactive algae are emerging as a cheaper and more sustainable alternative to chemical drugs. We havestudied the effect of local Polynesian plants and the local opportunistic algae Asparagopsis taxiformis onbatfish when orally administered. Weight gain and expression of two immune-related genes (lysozyme ge Lys G and transforming growth factor beta - TGF-b1) were studied to analyze immunostimulant activityof plants on P. orbicularis. Results showed that several plants increased Lys G and TGF-b1 expressionon orbicular batfish after 2 and 3 weeks of oral administration. A. taxiformis was the plant displaying themost promising results, promoting a weight gain of 24% after 3 weeks of oral administration andsignificantly increasing the relative amount of both Lys G and TGF-b1 transcripts in kidney and spleen ofP. orbicularis.
ISSN: 1050-4648

hal-01381334
https://hal-univ-perp.archives-ouvertes.fr/hal-01381334
DOI : 10.1016/j.fsi.2016.09.011

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
In this paper, we propose a benchmarking of supervised machine learning techniques (neural networks, Gaussian processes and support vector machines) in order to forecast the Global Horizontal solar Irradiance (GHI). We also include in this benchmark a simple linear autoregressive (AR) model as well as two naive models based on persistence of the GHI and persistence of the clear sky index (denoted herein scaled persistence model). The models are calibrated and validatedwith data from three French islands: Corsica (41.91°N; 8.73°E), Guadeloupe (16.26°N; 61.51°W) and Reunion (21.34°S ; 55.49°E). The main findings of this work are, that for hour ahead solar forecasting,the machine learning techniques slightly improve the performances exhibited by the linear AR and the scaled persistence model. However, the improvement appears to be more pronounced in case of unstable sky conditions.These nonlinear techniques start to outperform their simple counterparts for forecasting horizons greater than one hour.
ISSN: 0038-092X

Droits : info:eu-repo/semantics/OpenAccess
hal-01099211
https://hal.archives-ouvertes.fr/hal-01099211
https://hal.archives-ouvertes.fr/hal-01099211/document
https://hal.archives-ouvertes.fr/hal-01099211/file/Manuscript_Lauretetal_Rev_unmarked.pdf

Éditeur(s) : HAL CCSD National Institute of Environmental Health Sciences (NIEHS) National Institute of Environmental Health Sciences
Résumé : International audience
Long-term exposure to persistent pollutants with hormonal properties (endocrine-disrupting chemicals, EDCs) may contribute to the risk of prostate cancer (PCa). However, epidemiological evidence remains limited. We investigated the relationship between PCa and plasma concentrations of universally widespread pollutants, in particular p,p'-dichlorodiphenyl dichloroethene (DDE) and the non-dioxin like polychlorinated biphenyl congener 153 (PCB153). We evaluated before treatment 576 men with newly diagnosed PCa and 655 controls in Guadeloupe (French West Indies). Exposure was analyzed according to case-control status. Associations were assessed by unconditional logistic regression analysis, controlling for confounding factors. Missing data were handled by multiple imputation. We estimated a significant positive association between DDE and PCa (adjusted odds ratio [OR] 1.53; 95% CI 1.02, 2.30 for the highest versus lowest quintile of exposure; PTrend = 0.01). PCB153 was inversely associated with PCa (OR 0.30; 95% CI 0.19, 0.47 for the highest versus lowest quintile of exposure values; PTrend < 0.001). Also, PCB153 was more strongly associated to low-grade than high grade PCa. Associations of PCa with DDE and PCB153 were in opposite directions. This may reflect differences in the mechanisms of action of these EDCs, and although our findings need to be replicated in other populations, they are consistent with complex effects of EDCs on human health.
ISSN: 0091-6765

hal-01118553
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01118553
DOI : 10.1289/ehp.1408407
PUBMED : 25493337

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
The release of polycyclic aromatic hydrocarbons (PAHs) into the environment has increased very substantially over the last decades. PAHs are hydrophobic molecules which can accumulate in high concentrations in sediments acting then as major secondary sources. Fish contamination can occur through contact or residence nearby sediments or though dietary exposure. In this study, we analyzed certain physiological traits in unexposed fish (F1) issued from parents (F0) exposed through diet to three PAH mixtures at similar and environmentally relevant concentrations but differing in their compositions. For each mixture, no morphological differences were observed between concentrations. An increase in locomotor activity was observed in larvae issued from fish exposed to the highest concentration of a pyrolytic (PY) mixture. On the contrary, a decrease in locomotor activity was observed in larvae issued from heavy oil mixture (HO). In the case of the third mixture, light oil (LO), a reduction of the diurnal activity was observed during the setup of larval activity. Behavioral disruptions persisted in F1-PY juveniles and in their offspring (F2). Endocrine disruption was analyzed using cyp19a1b:GFP transgenic line and revealed disruptions in PY and LO offspring. Since no PAH metabolites were dosed in larvae, these findings suggest possible underlying mechanisms such as altered parental signaling molecule and/or hormone transferred in the gametes, eventually leading to early imprinting. Taken together, these results indicate that physiological disruptions are observed in offspring of fish exposed to PAH mixtures through diet.
ISSN: 0944-1344

hal-01121865
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01121865
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01121865/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01121865/file/Exposures%20of%20zebrafish_accepted.pdf
DOI : 10.1007/s11356-015-4157-8

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
Evolution involves interplay between natural selection and developmental constraints(1-3). This is seen, for example, when digits are lost from the limbs during evolution(1,3,4). Extant archosaurs (crocodiles and birds) show several instances of digit loss(3,5,6) under different selective regimes, and show limbs with one, two, three, four or the ancestral number of five digits. The `lost' digits sometimes persist for millions of years as developmental vestiges(7-10). Here we examine digit loss in the Nile crocodile and five birds, using markers of three successive stages of digit development. In two independent lineages under different selection, wing digit I and all its markers disappear. In contrast, hindlimb digit V persists in all species sampled, both as cartilage, and as Sox9-expressing precartilage domains, 250 million years after the adult digit disappeared. There is therefore a mismatch between evolution of the embryonic and adult phenotypes. All limbs, regardless of digit number, showed similar expression of sonic hedgehog (Shh). Even in the one-fingered emu wing, expression of posterior genes Hoxd11 and Hoxd12 was conserved, whereas expression of anterior genes Gli3 and Alx4 was not. We suggest that the persistence of digit V in the embryo may reflect constraints, particularly the conserved posterior gene networks associated with the zone of polarizing activity (ZPA(11)). The more rapid and complete disappearance of digit I may reflect its ZPA-independent specification, and hence, weaker developmental constraints. Interacting with these constraints are selection pressures for limb functions such as flying and perching. This model may help to explain the diverse patterns of digit loss in tetrapods. Our study may also help to understand how selection on adults leads to changes in development.
ISSN: 0028-0836

hal-01545485
https://hal.archives-ouvertes.fr/hal-01545485
DOI : 10.1038/nature12336

Éditeur(s) : HAL CCSD Wiley
Résumé : The evolutionary potential of long-lived species, such as forest trees, is fundamental for their local persistence under climate change (CC). Genome–environment association (GEA) analyses reveal if species in heterogeneous environments at the regional scale are under differential selection resulting in populations with potential preadaptation to CC within this area. In 79 natural [i]Fagus sylvatica[/i] populations, neutral genetic patterns were characterized using 12 simple sequence repeat (SSR) markers, and genomic variation (144 single nucleotide polymorphisms (SNPs) out of 52 candidate genes) was related to 87 environmental predictors in the latent factor mixed model, logistic regressions and isolation by distance/environmental (IBD/IBE) tests. SSR diversity revealed relatedness at up to 150m intertree distance but an absence of large-scale spatial genetic structure and IBE. In the GEA analyses, 16 SNPs in 10 genes responded to one or several environmental predictors and IBE, corrected for IBD, was confirmed. The GEA often reflected the proposed gene functions, including indications for adaptation to water availability and temperature. Genomic divergence and the lack of large-scale neutral genetic patterns suggest that gene flow allows the spread of advantageous alleles in adaptive genes. Thereby, adaptation processes are likely to take place in species occurring in heterogeneous environments, which might reduce their regional extinction risk under CC
ISSN: 0028-646X

hal-01309135
https://hal.archives-ouvertes.fr/hal-01309135
PRODINRA : 343710
DOI : 10.1111/nph.13809

Éditeur(s) : HAL CCSD
Résumé : Publié en septembre 2013 dans le "Journal de Gynécologie Obstétrique et Biologie de la Reproduction" vol.42 n°5 p.413-444
We review the epidemiological literature on the possible impact of chemical and physical factors on pregnancy outcome. Effects of in-utero exposures on child health are not considered here. The highest levels of evidence concern the effects of passive smoking (on fetal growth), of lead (pregnancy-induced hypertension, fetal growth), of some Polychlorinated Biphenyls (PCB; on fetal growth) and, to a lesser extent, of atmospheric pollutants (on fetal growth and preterm delivery). For the other compounds, in particular non-persistent chemicals, the literature, which is generally based on poor exposure assessment, is less informative. In conclusion, the last decades have witnessed the development of mother-child cohorts in which exposure biomarkers have been assayed, allowing a large number of publications. For some persistent compounds, for which efficient exposure assessment approaches have been used, the literature indicates a likely impact on pregnancy outcomes. With the exception of air pollutants, the literature on non-persistent compounds is little conclusive; the assay of exposure biomarkers in repeated biological samples collected at relevant time points could help further increase knowledge regarding any health impact.
https://hal.archives-ouvertes.fr/hal-00916684

hal-00916684
https://hal.archives-ouvertes.fr/hal-00916684
https://hal.archives-ouvertes.fr/hal-00916684/document
DOI : 10.1016/j.jgyn.2013.02.012

Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
BACKGROUND: Environmental exposures, including dietary contaminants, may influence the developing immune system. This study assesses the association between maternal pre-parturition consumption of seafood and wheeze, eczema, and food allergy in preschool children. Fish and shellfish were studied separately as they differ according to their levels of omega-3 polyunsaturated fatty acids (which have anti-allergic properties) and their levels of contaminants. METHODS: The PELAGIE cohort included 3421 women recruited at the beginning of pregnancy. Maternal fish and shellfish intake was measured at inclusion by a food frequency questionnaire. Wheeze, eczema, and food allergy were evaluated by a questionnaire completed by the mother when the child was 2 years old (n = 1500). Examination of the associations between seafood intake and outcomes took major confounders into account. Complementary sensitivity analyses with multiple imputation enabled us to handle missing data, due mostly to attrition. RESULTS: Moderate maternal pre-parturition fish intake (1 to 4 times a month) was, at borderline significance, associated with a lower risk of wheeze (adjusted OR = 0.69 (0.45-1.05)) before age 2, compared with low intake (< once/month). This result was not, however, consistent: after multiple imputation, the adjusted OR was 0.86 (0.63-1.17). Shellfish intake at least once a month was associated with a higher risk of food allergy before age 2 (adjusted OR = 1.62 (1.11-2.37)) compared to low or no intake (< once/month). Multiple imputation confirmed this association (adjusted OR = 1.52 (1.05-2.21)). CONCLUSIONS: This study suggests that maternal pre-parturition shellfish consumption may increase the risk of food allergy. Further large-scale epidemiologic studies are needed to corroborate these results, identify the contaminants or components of shellfish responsible for the effects observed, determine the persistence of the associations seen at age 2, and investigate potential associations with health effects observable at later ages, such as allergic asthma.
ISSN: 1476-069X

Droits : info:eu-repo/semantics/OpenAccess
inserm-00926282
http://www.hal.inserm.fr/inserm-00926282
http://www.hal.inserm.fr/inserm-00926282/document
http://www.hal.inserm.fr/inserm-00926282/file/1476-069X-12-102.pdf
DOI : 10.1186/1476-069X-12-102

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
AimThe global biodiversity crisis requires the identification of regions with high evolutionary potential, i.e. evolutionary hotspots (evospots). We created an analytical framework based on comparative phylogeography and coalescent methods to assess the dynamics of diversification and population persistence in the reef ecosystem of a little-studied region: the Southwestern Indian Ocean (SWIO).LocationCoral reefs of the SWIO, with comparative data from the Pacific Ocean.MethodsWe generated sequences of mitochondrial DNA (COI and 16S) for 10 widespread brittle-stars (345 specimens) from 21 localities (8 in the SWIO). We analysed them by combining comparative phylogeography approaches, coalescent-based methods, molecular clocks and the concept of evolutionarily significant units (ESUs) to draw conclusions about the drivers of biodiversity in the region.ResultsCryptic diversity was prevalent, increasing lineage diversity within the 10 nominal species by 70% within the SWIO and by 200% across the Indo-West Pacific. All seven new SWIO lineages meet the criteria for ESUs and at least six are biological species. We detected likely intraregional diversifications dating to the Plio-Pleistocene, supporting the SWIO as a generator of biodiversity. Geographical restriction of ESUs, long coalescent times (> 80 ka) and old in situ diversification (> 1 Ma) point to the persistence of populations over multiple glacio-eustatic cycles. We provide data suggesting demographic expansion during sea-level high stands. Regional connectivity was lower, and cryptic differentiation higher in lecithotrophs than in planktotrophs.Main conclusionsThe analytical framework based on a biodiversity survey makes it possible to identify evospots by assessing the potential of a region to maintain and generate biodiversity and by evaluating the evolutionary processes and potential drivers at play.
ISSN: 0305-0270

hal-01369697
http://hal.univ-reunion.fr/hal-01369697
DOI : 10.1111/jbi.12155

Éditeur(s) : HAL CCSD IWA Publishing
Résumé : International audience
The widely occurring degradation product aminomethylphosphonic acid (AMPA) is a result of glyphosate and amino-polyphosphonate degradation. Massive use of the parent compounds leads to the ubiquity of AMPA in the environment, and particularly in water. The purpose of this review is to summarize and discuss current insights into AMPA formation, transport, persistence and toxicity. In agricultural soils, AMPA is concentrated in the topsoil, and degrades slowly in most soils. It can reach shallow groundwater, but rarely managed to enter deep groundwater. AMPA is strongly adsorbed to soil particles and moves with the particles towards the stream in rainfall runoff. In urban areas, AMPA comes from phosphonates and glyphosate in wastewater. It is commonly found at the outlets of Wastewater Treatment Plants (WWTP). Sediments tend to accumulate AMPA, where it may be biodegraded. Airborne AMPA is not negligible, but does wash-out with heavy rainfall. AMPA is reported to be persistent and can be biologically degraded in soils and sediments. Limited photodegradation in waters exists. AMPA mainly has its sources in agricultural leachates, and urban wastewater effluents. The domestic contribution to urban loads is negligible. There is a critical lack of epidemiological data - especially on water exposure - to understand the toxicological effects, if any, of AMPA on humans. Fortunately, well operated water treatment plants remove a significant proportion of the AMPA from water, even though there are not sufficient regulatory limits for metabolites.
ISSN: 0043-1354

hal-01516026
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01516026
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01516026/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01516026/file/Grandcoin%20et%20al.%20-%20AminoMethylPhosphonic%20acid%20%28AMPA%29%20in%20natural%20water.pdf
DOI : 10.1016/j.watres.2017.03.055

Éditeur(s) : HAL CCSD BMJ Publishing Group
Résumé : International audience
OBJECTIVES: The time from the prenatal period through early childhood is an important window of vulnerability for the developing immune and respiratory systems, both sensitive to environmental chemicals such as solvents. This study sought to examine the effects of solvent exposure during the prenatal and postnatal periods on wheezing, eczema and food allergies in early childhood. METHODS: This study, based on the PELAGIE cohort, included 1505 mother-child pairs with measurements of prenatal and postnatal solvent exposures and data on wheezing, eczema or food allergies. The maternal occupation reported at inclusion, in early pregnancy allowed us to define prenatal occupational solvent exposure (by three specific job-exposure matrices). Data on prenatal and postnatal domestic solvent exposure, that is exposure to products that contain solvents, were obtained from self-administered questionnaires, once at inclusion and again when the child was 2 years old. Outcome data was collected at the 2-year follow-up. Associations between exposures and outcomes were estimated by logistic regression models, after adjustment for potential confounders. RESULTS: No association was observed between prenatal exposure to solvents and the outcomes studied. Postnatal exposure was associated with an increased risk of wheezing (OR=1.80 (95% CI 1.25 to 2.59)) which persisted after adjustment for prenatal exposure. No significant association was observed with eczema or food allergies. CONCLUSIONS: Postnatal exposure to solvent-containing products in the home may increase the risk of wheezing in early childhood. Follow-up studies are needed to determine if the health effects observed at age 2 persist at later ages.
ISSN: 1351-0711

hal-01063913
https://hal.archives-ouvertes.fr/hal-01063913
DOI : 10.1136/oemed-2013-102036
PUBMED : 24996679

Éditeur(s) : Pergamon-elsevier Science Ltd
Résumé : Consumption of marine organisms represents one of the main exposure sources of contaminants for human populations. To obtain a global view of the contamination in commercial fish in the NW Mediterranean Sea, we analysed four types of priority contaminants (PCBs, PBDEs, Hg and Cs-137) in the European hake, Merluccius merluccius, from the Gulf of Lions in relation with organism's trophic level (delta N-15). All contaminants presented a significant increase in concentration in hake muscle with trophic level. However, obvious differences between contaminants were evidenced. Biomagnification factors (BMF and FWMF) along the hake food web were higher for Hg and CB-153 than for BDE-47 and Cs-137, and increase in contaminant concentration with trophic level occurred at different rates depending on contaminants. Such differences of biomagnification patterns can be related to physico-chemical properties of the different contaminants. (C) 2012 Elsevier Ltd. All rights reserved.
Marine Pollution Bulletin (0025-326X) (Pergamon-elsevier Science Ltd), 2012-05 , Vol. 64 , N. 5 , P. 974-983

Droits : 2012 Elsevier Ltd. All rights reserved.
http://archimer.ifremer.fr/doc/00085/19583/17484.pdf
DOI:10.1016/j.marpolbul.2012.02.014
http://archimer.ifremer.fr/doc/00085/19583/

Éditeur(s) : HAL CCSD Wiley
Résumé : International audience
Well-designed and effectively managed networks of marine reserves can be effective tools for both fisheries management and biodiversity conservation. Connectivity, the demographic linking of local populations through the dispersal of individuals as larvae, juveniles or adults, is a key ecological factor to consider in marine reserve design, since it has important implications for the persistence of metapopulations and their recovery from disturbance. For marine reserves to protect biodiversity and enhance populations of species in fished areas, they must be able to sustain focal species (particularly fishery species) within their boundaries, and be spaced such that they can function as mutually replenishing networks whilst providing recruitment subsidies to fished areas. Thus the configuration (size, spacing and location) of individual reserves within a network should be informed by larval dispersal and movement patterns of the species for which protection is required. In the past, empirical data regarding larval dispersal and movement patterns of adults and juveniles of many tropical marine species have been unavailable or inaccessible to practitioners responsible for marine reserve design. Recent empirical studies using new technologies have also provided fresh insights into movement patterns of many species and redefined our understanding of connectivity among populations through larval dispersal. Our review of movement patterns of 34 families (210 species) of coral reef fishes demonstrates that movement patterns (home ranges, ontogenetic shifts and spawning migrations) vary among and within species, and are influenced by a range of factors (e.g. size, sex, behaviour, density, habitat characteristics, season, tide and time of day). Some species move <0.1–0.5 km (e.g. damselfishes, butterflyfishes and angelfishes), <0.5–3 km (e.g. most parrotfishes, goatfishes and surgeonfishes) or 3–10 km (e.g. large parrotfishes and wrasses), while others move tens to hundreds (e.g. some groupers, emperors, snappers and jacks) or thousands of kilometres (e.g. some sharks and tuna). Larval dispersal distances tend to be <5–15 km, and self-recruitment is common. Synthesising this information allows us, for the first time, to provide species, specific advice on the size, spacing and location of marine reserves in tropical marine ecosystems to maximise benefits for conservation and fisheries management for a range of taxa. We recommend that: (i) marine reserves should be more than twice the size of the home range of focal species (in all directions), thus marine reserves of various sizes will be required depending on which species require protection, how far they move, and if other effective protection is in place outside reserves; (ii) reserve spacing should be <15 km, with smaller reserves spaced more closely; and (iii) marine reserves should include habitats that are critical to the life history of focal species (e.g. home ranges, nursery grounds, migration corridors and spawning aggregations), and be located to accommodate movement patterns among these. We also provide practical advice for practitioners on how to use this information to design, evaluate and monitor the effectiveness of marine reserve networks within broader ecological, socioeconomic and management contexts.
ISSN: 1464-7931

Droits : http://creativecommons.org/licenses/by-nc-nd/
hal-01334353
https://hal-univ-perp.archives-ouvertes.fr/hal-01334353
https://hal-univ-perp.archives-ouvertes.fr/hal-01334353/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01334353/file/Green_et_al-2015-Biological_Reviews.pdf
DOI : 10.1111/brv.12155

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
In fold and thrust belts drainage organization and patterns of sedimentation depend conceptually on the ability or not for preexisting reaches to incise uplifting thrust sheets. In this study we investigate experimentally the dynamics of drainage network in a wedge submitted to shortening and erosion. It allows us to reproduce and to monitor the interactions between tectonics, erosion and sedimentation during the development of up to five successive thrust sheets. In the experiments channels adjust to uplift rate by both increasing their slope and narrowing their channels as it is observed in nature. The series of experiments shows that the proportion of persistent preexisting transverse channels increases with the ratio of rainfall over shortening rates. The experiments confirm the view that the competition between discharge and tectonic uplift controls along-strike variations in sediment flux in sedimentary basins by controlling the drainage organization. If the transverse channels draining a wedge are not diverted, a line-source dispersal system develops in front of the active structure. If channels are diverted in the backlimb of the frontal structure it results in point-sourced depositional systems separated by areas fed only by small channels developing in the front of the wedge. Fans accumulated in front of the active structures reveal two stages of sedimentation, one of progradation, while the frontal structure is active and a second one of valley backfilling and thrust sealing during internal deformation of the wedge. The experiments also suggest that spatial variations in rock uplift rate along a thrust front may be evidenced by minimum-discharge variations of persistent transverse channels.
ISSN: 0040-1951

insu-01252482
https://hal-insu.archives-ouvertes.fr/insu-01252482
DOI : 10.1016/j.tecto.2015.09.007

Éditeur(s) : HAL CCSD
Résumé : Semi-volatile organic compounds (SVOCs) refer to a broad spectrum of molecules from different chemical families that have numerous properties. They can be used as pesticides, plasticizers, flame retardants, surfactants, lubricants, etc. Consequently, they are introduced in numerous applications in buildings or used daily by the entire population. Once emitted through evaporation or abrasion in the indoor environment or introduced from the outdoors, their chemical or biological degradation is limited, and they persist indoors. This persistence also explains why some SVOCs that were banned a few years ago are still detected in the air and dust inside buildings. In indoor environments, SVOCs are divided between the gas phase, airborne particles, and dust settled on floors and surfaces. SVOCs are of concern due to their established or suspected health effects and their widespread exposure through different environmental media and pathways. The objective of the thesis was to study the concentrations of 66 SVOCs on airborne particles (PM10) and 48 SVOCs in settled dust in two samples of dwellings randomly selected across France. PM10 were sampled during the nationwide housing survey carried out by the French Observatory of indoor air quality in 2003-2005. The dust samples were collected from vacuum cleaner bags during a nationwide survey carried out in French dwellings where at least one child aged 6 months to 6 years lived (2008-2009). The SVOCs to be analyzed had prior been selected using a ranking method based on their toxicity and indoor concentrations. The data analysis focused in particular on the identification of French specificities in terms of detected molecules and measured concentrations. It highlighted some determinants of exposure, e.g., influence of particle size, type of dust collected, dust bioaccessibility, which are not always considered and limit the comparability of results. The measured concentrations were also used to assess the health ranking implemented prior to this work and to confirm its relevance. The concentrations measured both in the air and in settled dust were compared to study the similarities in terms of concentrations and SVOC mixtures. Finally, the exposure doses to SVOCs were calculated for both a child and an adult to assess the respective contributions of inhalation and ingestion to these compounds in particulate phase in dwellings.
Les composés organiques semi-volatils (COSV) font l’objet d’une attention croissante depuis une dizaine d’années. Utilisés dans de nombreux produits et matériaux du quotidien, ils sont émis dans les bâtiments par dispersion lors de l’usage, par évaporation ou abrasion. Du fait de leurs caractéristiques physico-chimiques, ces composés se répartissent à la fois dans l’air, en phases gazeuse et particulaire, et dans les poussières déposées au sol, sur le mobilier et les objets. Compte tenu du temps passé par la population dans les bâtiments, en particulier par les populations sensibles comme les enfants, les femmes enceintes et les personnes âgées, l’exposition à ces substances mérite d’être documentée, tenant compte des voies d’exposition en jeu : inhalation, ingestion et contact cutané. La thèse a porté sur les COSV présents en phase particulaire dans les logements. L’objectif de la thèse visait à exploiter les mesures de 66 COSV dans les particules en suspension de diamètre inférieur à 10 µm (PM10) et de 48 COSV dans les poussières au sol de taille inférieure à 100 µm considérées comme étant celles adhérant à la peau. Ces mesures ont été réalisées dans le cadre de deux campagnes nationales : la campagne « Logements » de l’Observatoire de la qualité de l’air intérieur conduite en 2003-2005 et l’enquête Plomb-Habitat dont les prélèvements ont eu lieu en 2008-2009. Une hiérarchisation des molécules jugées prioritaires au regard de leur impact sanitaire potentiel avait permis au préalable d’établir la liste des COSV à mesurer. L’exploitation de ces données de contamination a notamment porté sur l’identification d’éventuelles spécificités françaises au regard des molécules en présence et/ou des concentrations mesurées. Elle a permis de mettre en lumière un ensemble de facteurs déterminants de l’exposition (influence de la taille des particules, du type de poussières collectées, de leur bioaccessibilité), qui ne sont pas toujours considérés et qui limitent par ailleurs la comparabilité des résultats. Les concentrations mesurées ont aussi permis d’évaluer rétrospectivement la hiérarchisation sanitaire et d’en confirmer la pertinence. Les concentrations des COSV quantifiés à la fois dans l’air et au sol ont été mises en perspective afin d’examiner dans quelle mesure les particules en suspension et les poussières déposées sont similaires en termes de concentrations et de mélanges de COSV en présence. Enfin, l‘estimation des doses d’exposition aux COSV à partir d’équations simples, de variables humaines d’exposition et des données de contamination a permis une première évaluation des contributions respectives de l’inhalation et de l’ingestion aux expositions domestiques des enfants et adultes à ces composés en phase particulaire.
https://tel.archives-ouvertes.fr/tel-01308524

NNT : 2015REN1B033
tel-01308524
https://tel.archives-ouvertes.fr/tel-01308524
https://tel.archives-ouvertes.fr/tel-01308524/document
https://tel.archives-ouvertes.fr/tel-01308524/file/MANDINCorinne.pdf

Éditeur(s) : HAL CCSD Elsevier
Résumé : SUBSURF
Statistical sequential analysis was performed on a series of sediment cores collected from the Têt prodelta in the Gulf of Lions, northwestern Mediterranean Sea, between October 2003 and October 2004. Seabed changes during that period were correlated to hydrodynamic conditions (waves and currents) and river discharge. Low sediment supply prevents full preservation of new sediment strata on this low-accumulation prodelta located on a microtidal, storm-dominated inner shelf. Severe meteorological events caused a rapid succession of erosion and deposition phases. For example, the December 2003 flood and storm produced a flood layer deposit that persisted for 2 months with only slight transformations due to early diagenesis and/or bioturbation, until a new storm event eroded this layer. A typical sedimentary sequence was observed for the secular deposits composed of a 10-cm-thick sandy layer overlaying siltyclayey layers. These characteristic features were used to analyse the last millennia sedimentary record of the Têt prodelta. The low preservation of freshly deposited sediments and variable sedimentation rates during the last millennia period yield a sedimentary sequence formed by the outcropping of muddy prodeltaic units intersected by heterogeneous siltysandy units similar to those formed under present day hydrodynamic conditions. No flood layer was found related to catastrophic flooding of the last century in the sedimentary record. The Little Ice Age ( 1550–1850 AD) probably favoured the formation of a well-developed muddy prodelta in the mouth of the Têt River. Later on, the decrease of sediment supply by rivers due to climate change and/or human activities (damming, irrigation), and the increase of the number of high-energy storms reaching the coast, induced a coarsening of the top sediment layer on this prodelta. This modern change of the substrate is also observed in the composition of benthic biota found in the substrate
ISSN: 0025-3227

hal-00407662
https://hal.archives-ouvertes.fr/hal-00407662
DOI : 10.1016/j.margeo.2007.04.009