Éditeur(s) : HAL CCSD BioMed Central
Résumé : International audience
Background: HCV treatment uptake has drastically increased in HIV-HCV coinfected patients in France since direct-acting antiviral (DAA) treatment approval, resulting in HCV cure in 63% of all HIV-HCV patients by the end of 2015. We investigated the impact of scaling-up DAA on HCV prevalence in the whole HIV population and in various risk groups over the next 10 years in France using a transmission dynamic compartmental model.Methods: The model was based on epidemiological data from the French Dat’AIDS cohort. Eight risk groups wereconsidered, including high-risk (HR) and low-risk (LR) men who have sex with men (MSM) and male/female heterosexuals,intra-venous drug users, or patients from other risk groups. The model was calibrated on prevalence and incidence dataobserved in the cohort between 2012 and 2015.Results: On January 1, 2016, 156,811 patients were registered as infected with HIV in France (24,900 undiagnosedpatients) of whom 7938 (5.1%) had detectable HCV-RNA (722 undiagnosed patients). Assuming a treatmentcoverage (TC) rate of 30%/year (i.e., the observed rate in 2015), model projections showed that HCV prevalenceamong HIV patients is expected to drop to 0.81% in 2026. Sub-analyses showed a similar decrease of HIV-HCVprevalence in most risk groups, including LR MSM. Due to higher infection and reinfection rates, predicted prevalencein HR MSM remained stable from 6.96% in 2016 to 6.34% in 2026. Increasing annual TC rate in HR MSM to 50/70%would decrease HCV prevalence in this group to 2.35/1.25% in 2026. With a 30% TC rate, undiagnosed patients wouldaccount for 34% of HCV infections in 2026.Conclusions: Our model suggests that DAA could nearly eliminate coinfection in France within 10 years for most riskgroups, including LR MSM. Elimination in HR MSM will require increased TC.
ISSN: 1741-7015

Droits : info:eu-repo/semantics/OpenAccess
inserm-01685739
http://www.hal.inserm.fr/inserm-01685739
http://www.hal.inserm.fr/inserm-01685739/document
http://www.hal.inserm.fr/inserm-01685739/file/2017%2C%20Virlogeux%20-%20Modeling%20HIV-HCV%20coinfection.pdf
DOI : 10.1186/s12916-017-0979-1

Éditeur(s) : HAL CCSD Cerimes
Résumé : L'ensemble des articles est archivé sur ArchiveTémaTice. Les actes sont aussi accessibles sur le site du colloque http://www.cerimes.fr/colloquefrancomexicain
Les textes qui composent ces actes ont été présentés à l'occasion du premier colloque franco-mexicain en sciences de la communication, organisé par la Asociación mexicana en Ciencias de la comunicación (AMIC) et la Société Française des Sciences de l'Information et de la Communication (SFSIC), à Mexico, du 8 au 10 avril 2002.

Les médias classiques: radio, télévision (8 avril 2002)
Introduction . La coopération scientifique bilatérale et l'interculturel dans l'activité de recherche, Bruno Ollivier
La recherche française sur le média et les discours télévisuels: éléments pour un bilan prospectif, Guy Lochard
Parcours de la programmation télévisée au Mexique, Florence Toussaint
El regimen de la television hertziana en Mexico, Claudia I. Garcia Rubio
La question de l'éthos et du genre en communication politique, Simone Bonnafous
L'exposition de la vie privée dans les médias, André Vitalis

Identités, culture, communication (9 avril 2002)
Reconfiguraciones cimunicativas de la socialidad y reencantamientos de la communication identidad, Jesus Martin-Barbero
Identité, culture et communication, Jean François Tetu
Las organizaciones civiles en las radiodifusoras comerciales, Dr. José Cisneros E.
Les SIC et l'altérité: démarches d'une recherche sur la Chine. réflexions épitstémologiques sur les analyses de corpus à base communicationnelles de langue et de culture non-maternelles, Dominique Colomb
Transicion, reforma del estado y medios de comunicacion en Mexico, Dr. Javier Esteinou Madrid
Medios masivos y formacion psicosocial, Enrique Guinsberg

Technologies d'information et de communication ( 10 avril 2002)
Quoi de nouveau dans la recherche française en informatique et communication ? Bernard Miege
Convergencia tecnologica: perspectivas de investigacion en Mexico, Delia Crovi Druetta
Medias, technologies et public: la notion de projet au cœur d'une éventuelle médiation, Claire Noy
La formacion de profesores de educacion superior en el uso de la computadora y la internet. reflexioànes sobre el tema, Luz Maria Garay Cruz
Vers un retour à une lecture non linéaire, Schmidt C. T, Roxin I.(), Mercier D, Hufschmitt B. & Cotten J.-P
NTIC et éducation à distance. Le cas d'Edusat au Mexique face au cas français, Norma Veronica Fernandez Arriaga.
Les sciences de l'éducation et les sciences de la communication en dialogue: à propos des médias et des technologies éducatives, Geneviève Jacquinot-Delaunay
Internet et Intranet dans les organisations "un scénario récurrent", Jean-Antoine Corbalan
De l'université virtuelle au campus numérique : simple effet de traduction ou changement de paradigme, Françoise Thibault
Competencias mediacionales de los sujetos en programas educativos en entornos digitales, Maria Elena Chan Nunez
Le journal quotidien sur le Web. L'identité éditoriale au risque du formatage, Annelise Touboul
Conclusion, Carmen Gomez-Mont
Premier colloque franco-mexicain de sciences de la communication
Mexico, France

Droits : info:eu-repo/semantics/OpenAccess
ISBN : http://www.cerimes.education.fr
edutice-00000362
https://edutice.archives-ouvertes.fr/edutice-00000362
https://edutice.archives-ouvertes.fr/edutice-00000362/document
https://edutice.archives-ouvertes.fr/edutice-00000362/file/actes.pdf

Éditeur(s) : Amer Meteorological Soc
Résumé : Salinity measurements from 119 surface drifters in 2007-12 were assessed; 80% [Surface Velocity Program with a barometer with a salinity sensor (SVP-BS)] and 75% [SVP with salinity (SVP-S)] of the salinity data were found to be usable, after editing out some spikes. Sudden salinity jumps are found in drifter salinity records that are not always associated with temperature jumps, in particular in the wet tropics. A method is proposed to decide whether and how to correct those jumps, and the uncertainty in the correction applied. Northeast of South America, in a region influenced by the Amazon plume and fresh coastal water, drifter salinity is very variable, but a comparison with data from the Soil Moisture and Ocean Salinity satellite suggests that this variability is usually reasonable. The drifter salinity accuracy is then explored based on comparisons with data from Argo floats and from thermosalinographs (TSGs) of ships of opportunity. SVP-S/SVP-BS drifter records do not usually present significant biases within the first 6 months, but afterward biases sometimes need to be corrected (altogether, 16% of the SVP-BS records). Biases start earlier after 3 months for drifters not protected by antifouling paint. For the few drifters for which large corrections were applied to portions of the record, the accuracy cannot be proven to be better than 0.1 psu, and it cannot be proven to be better than 0.5 psu for data in the largest variability area off northeast South America. Elsewhere, after excluding portions of the records with suspicious salinity jumps or when large corrections were applied, the comparisons rule out average biases in individual drifter salinity record larger than 0.02 psu (midlatitudes) and 0.05 psu (tropics).
Journal Of Atmospheric And Oceanic Technology (0739-0572) (Amer Meteorological Soc), 2014-04 , Vol. 31 , N. 4 , P. 967-983

Droits : 2014 American Meteorological Society
http://archimer.ifremer.fr/doc/00190/30095/28748.pdf
DOI:10.1175/JTECH-D-13-00158.1
http://archimer.ifremer.fr/doc/00190/30095/

Éditeur(s) : HAL CCSD American Association for the Advancement of Science
Résumé : The biodiversity-productivity relationship (BPR) is foundational to our understanding of the global extinction crisis and its impacts on ecosystem functioning. Understanding BPR is critical for the accurate valuation and effective conservation of biodiversity. Using ground-sourced data from 777,126 permanent plots, spanning 44 countries and most terrestrial biomes, we reveal a globally consistent positive concave-down BPR, showing that continued biodiversity loss would result in an accelerating decline in forest productivity worldwide. The value of biodiversity in maintaining commercial forest productivity alone-US$166 billion to 490 billion per year according to our estimation-is more than twice what it would cost to implement effective global conservation. This highlights the need for a worldwide reassessment of biodiversity values, forest management strategies, and conservation priorities.
ISSN: 0036-8075

hal-01607784
https://hal.archives-ouvertes.fr/hal-01607784
DOI : 10.1126/science.aaf8957
PRODINRA : 389856

Éditeur(s) : HAL CCSD Elsevier Masson
Résumé : International audience
ISSN: 0033-2984

hal-01678151
https://hal.univ-antilles.fr/hal-01678151
DOI : 10.1016/j.psfr.2014.04.002

Éditeur(s) : HAL CCSD
Résumé : International audience
Cumulative human impacts have led to the degradation of marine ecosystems and thedecline of biodiversity in the European and contiguous seas. Effective conservationmeasures are urgently needed to reverse these trends. Conservation must entail societalchoices, underpinned by human values and worldviews that differ between the countriesbordering these seas. Social, economic and political heterogeneity adds to the challenge ofbalancing conservation with sustainable use of the seas. Comprehensive macro-regionalcoordination is needed to ensure effective conservation of marine ecosystems andbiodiversity of this region. Under the European Union Horizon 2020 framework programme,the MarCons COST action aims to promote collaborative research to support marinemanagement, conservation planning and policy development. This will be achieved bydeveloping novel methods and tools to close knowledge gaps and advance marineconservation science. This action will provide support for the development of macro-regional and national policies through six key actions: to develop tools to analysecumulative human impacts; to identify critical scientific and technical gaps in conservationefforts; to improve the resilience of the marine environment to global change and biologicalinvasions; to develop frameworks for integrated conservation planning across terrestrial,freshwater, and marine environments; to coordinate marine conservation policy acrossnational boundaries; and to identify effective governance approaches for marine protectedarea management. Achieving the objectives of these actions will facilitate the integration ofmarine conservation policy into macro-regional maritime spatial planning agendas for theEuropean and contiguous seas, thereby offsetting the loss of biodiversity and ecosystemservices in this region.
Research Ideas and Outcomes

hal-01474085
https://hal-univ-perp.archives-ouvertes.fr/hal-01474085
https://hal-univ-perp.archives-ouvertes.fr/hal-01474085/document
https://hal-univ-perp.archives-ouvertes.fr/hal-01474085/file/RIO_article_11884.pdf
DOI : 10.3897/rio.3.e11884

Éditeur(s) : Amer Geophysical Union
Résumé : Sea surface salinity (SSS) measured from space by the Soil Moisture and Ocean Salinity (SMOS) mission is validated in the subtropical North Atlantic Ocean. 39 transects of ships of opportunity equipped with thermosalinographs (TSG) crossed that region from 2010 to 2012, providing a large database of ground truth SSS. SMOS SSS is also compared to Aquarius SSS. Large seasonal biases remain in SMOS and Aquarius SSS. In order to look at the capability of satellite SSS to monitor spatial variability, especially at scales less than 300 km (not monitored with the Argo network), we first apply a monthly bias correction derived from satellite SSS and In Situ Analysis System (ISAS) SSS differences averaged over the studied region. Ship SSS averaged over 25 km is compared with satellite and ISAS SSS. Similar statistics are obtained for SMOS, Aquarius and ISAS products (root mean square error of about 0.15 and global correlation coefficient r of about 0.92). However, in the above statistics, SSS varies due to both large scale and mesoscale (here, for scales around 100 km) variability. In order to focus on mesoscale variability, we consider SSS anomalies with respect to a monthly climatology. SMOS SSS and Aquarius SSS anomalies are more significantly correlated (r > 0.5) to TSG SSS anomaly than ISAS. We show the effective gain of resolution and coverage provided by the satellite products over the interpolated in situ data. We also show the advantage of SMOS (r=0.57) over Aquarius (r=0.52) to reproduce SSS mesoscale features.
Journal Of Geophysical Research-oceans (0148-0027) (Amer Geophysical Union), 2014-12 , Vol. 119 , N. 12 , P. 8878-8896

Droits : 2014. American Geophysical Union. All Rights Reserved.
http://archimer.ifremer.fr/doc/00210/32150/34082.pdf
DOI:10.1002/2013JC009610
http://archimer.ifremer.fr/doc/00210/32150/

Éditeur(s) : HAL CCSD Météo et Climat
Résumé : International audience
D'initiative française, le projet international HyMeX a pour objectif d'améliorer la compréhension du cycle de l'eau en Méditerranée, de sa variabilité, de l'échelle de l'événement météorologique aux échelles saisonnières et interannuelles, et de ses caractéristiques sur une décennie, dans un contexte de changement global. Le projet est motivé par le rôle déterminant des processus de mésoéchelle, couplés entre l'atmosphère, la mer et la terre, sur la variabilité du système climatique et sur le déclenchement d'événements hydrométéorologiques extrêmes (précipitations et inondations, vents forts et convection océanique, canicules et sécheresses). Le projet vise enfin à évaluer les conséquences de ces événements extrêmes sur la vulnérabilité sociale et économique de cette région et sa capacité d'adaptation.
ISSN: 0026-1181

hal-00828758
https://hal.archives-ouvertes.fr/hal-00828758
https://hal.archives-ouvertes.fr/hal-00828758/document
https://hal.archives-ouvertes.fr/hal-00828758/file/meteo_2013_80_23%20%281%29.pdf
DOI : 10.4267/2042/48792

Éditeur(s) : HAL CCSD Geological Society, London
Résumé : This collection of papers presents recent advances in the study of deformation mechanisms and rheology and their applications to tectonics. Many of the contributions exploit new petrofabric techniques, particularly electron backscatter diffraction, to help understand the evolution of rock microstructure and mechanical properties.
Deformation Mechanisms, Rheology and Tectonics: Microstructures, Mechanics and Anistropy;Geological

hal-00685575
https://hal.archives-ouvertes.fr/hal-00685575

Éditeur(s) : HAL CCSD
Résumé : International audience
Objective Oxidative stress, excess production of reactive oxygen species (ROS) and intense colonization of the respiratory tract by microorganisms are described in CF patients, leading to an influx in macrophages. This results in activation of NADPH oxidase that yields ROS, initiating the oxidative burst responsible for pathogen destruction. We showed that phagocytosis was altered in CF macrophages, yet oxidative status in this cell was not defined. The objective of this study is to draw a link between oxidative stress and plasma membrane integrity in CF macrophages, since lipid peroxidation is known to alter cell membrane. Methods Peripheral blood monocytes-derived macrophages were obtained from CF patients and healthy subjects. Plasma membrane fluidity was assessed with di4-ANEPPDHQ and oxidative status was measured with ROS indicating probes. Results In CF macrophages, membrane fluidity was increased whereas lipid peroxidation was diminished. Surprisingly, general oxidative status remained similar to the one observed in non-CF macrophages. Also, CF macrophages did not abolish chemically induced-oxidative stress. In non-CF macrophages, treatment with cholesterol slightly increased membrane fluidity whereas LPS treatment had no effect. Conclusion CF macrophages displayed an increased membrane fluidity associated with a decreased lipid peroxidation. This raises the hypothesis that membrane alteration in CF macrophages may be due to other mechanism than oxidative stress. Nevertheless, since the killing capacity of CF macrophage is defective, a deregulation of O•−2 production is very likely, suggesting alteration of NADPH oxidase or mitochondrial dysfunction
the 38th European Cystic Fibrosis Conference
Vienne, Austria

hal-01162769
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01162769
DOI : 10.1016/S1569-1993(15)30217-4

Éditeur(s) : HAL CCSD
Résumé : International audience
Recent studies have shown that accounting for intraspecific trait variation (ITV) may better address major questions in community ecology. However, a general picture of the relative extent of ITV compared to interspecific trait variation in plant communities is still missing. Here, weconducted a meta-analysis of the relative extent of ITV within and among plant communities worldwide, using a data set encompassing 629 communities (plots) and 36 functional traits. Overall, ITV accounted for 25% of the total trait variation within communities and 32% of the totaltrait variation among communities on average. The relative extent of ITV tended to be greater for whole-plant (e.g. plant height) vs. organ-level traits and for leaf chemical (e.g. leaf N and P concentration) vs. leaf morphological (e.g. leaf area and thickness) traits. The relative amount of ITV decreased with increasing species richness and spatial extent, but did not vary with plant growth form or climate. These results highlight global patterns in the relative importance of ITV in plant communities, providing practical guidelines for when researchers should include ITV in trait-based community and ecosystem studies.
Ecology Letters

hal-01237101
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01237101
DOI : 10.1111/ele.12508
PUBMED : 26415616

Éditeur(s) : HAL CCSD Wiley/Blackwell
Résumé : 4 pages
International audience
This article documents the addition of 268 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Alburnoides bipunctatus, Chamaerops humilis, Chlidonias hybrida, Cyperus papyrus, Fusarium graminearum, Loxigilla barbadensis, Macrobrachium rosenbergii, Odontesthes bonariensis, Pelteobagrus vachelli, Posidonia oceanica, Potamotrygon motoro, Rhamdia quelen, Sarotherodon melanotheron heudelotii, Sibiraea angustata, Takifugu rubripes, Tarentola mauritanica, Trimmatostroma sp. and Wallago attu. These loci were cross-tested on the following species: Alburnoides fasciatus, Alburnoides kubanicus, Alburnoides maculatus, Alburnoides ohridanus, Alburnoides prespensis, Alburnoides rossicus, Alburnoides strymonicus, Alburnoides thessalicus, Alburnoides tzanevi, Carassius carassius, Fusarium asiaticum, Leucaspius delineatus, Loxigilla noctis dominica, Pelecus cultratus, Phoenix canariensis, Potamotrygon falkneri, Trachycarpus fortune and Vimba vimba.
ISSN: 1755-098X

hal-00823716
https://hal.archives-ouvertes.fr/hal-00823716
DOI : 10.1111/1755-0998.12095
PUBMED : 23521844

Éditeur(s) : HAL CCSD Wiley/Blackwell
Résumé : International audience
This article documents the addition of 512 microsatellite marker loci and nine pairs of Single Nucleotide Polymorphism (SNP) sequencing primers to the Molecular Ecology Resources Database. Loci were developed for the following species: Alcippe morrisonia morrisonia, Bashania fangiana, Bashania fargesii, Chaetodon vagabundus, Colletes floralis, Coluber constrictor flaviventris, Coptotermes gestroi, Crotophaga major, Cyprinella lutrensis, Danaus plexippus, Fagus grandifolia, Falco tinnunculus, Fletcherimyia fletcheri, Hydrilla verticillata, Laterallus jamaicensis coturniculus, Leavenworthia alabamica, Marmosops incanus, Miichthys miiuy, Nasua nasua, Noturus exilis, Odontesthes bonariensis, Quadrula fragosa, Pinctada maxima, Pseudaletia separata, Pseudoperonospora cubensis, Podocarpus elatus, Portunus trituberculatus, Rhagoletis cerasi, Rhinella schneideri, Sarracenia alata, Skeletonema marinoi, Sminthurus viridis, Syngnathus abaster, Uroteuthis (Photololigo) chinensis, Verticillium dahliae, Wasmannia auropunctata, and Zygochlamys patagonica. These loci were cross-tested on the following species: Chaetodon baronessa, Falco columbarius, Falco eleonorae, Falco naumanni, Falco peregrinus, Falco subbuteo, Didelphis aurita, Gracilinanus microtarsus, Marmosops paulensis, Monodelphis Americana, Odontesthes hatcheri, Podocarpus grayi, Podocarpus lawrencei, Podocarpus smithii, Portunus pelagicus, Syngnathus acus, Syngnathus typhle,Uroteuthis (Photololigo) edulis, Uroteuthis (Photololigo) duvauceli and Verticillium albo-atrum. This article also documents the addition of nine sequencing primer pairs and sixteen allele specific primers or probes for Oncorhynchus mykiss and Oncorhynchus tshawytscha; these primers and assays were cross-tested in both species.
ISSN: 1755-098X

hal-01094222
https://hal-agroparistech.archives-ouvertes.fr/hal-01094222
DOI : 10.1111/j.1755-0998.2010.02916.x

Éditeur(s) : HAL CCSD Elsevier
Résumé : International audience
Magnetic Resonance Imaging (MRI), a reference examination for cardiac morphology and function in humans, allows to image the cardiac right ventricle (RV) with high spatial resolution. The segmentation of the RV is a difficult task due to the variable shape of the RV and its ill-defined borders in these images. The aim of this paper is to evaluate several RV segmentation algorithms on common data. More precisely, we report here the results of the Right Ventricle Segmentation Challenge (RVSC), concretized during the MICCAI'12 Conference with an on-site competition. Seven automated and semi-automated methods have been considered, along them three atlas-based methods, two prior based methods, and two prior-free, image-driven methods that make use of cardiac motion. The obtained contours were compared against a manual tracing by an expert cardiac radiologist, taken as a reference, using Dice metric and Hausdorff distance. We herein describe the cardiac data composed of 48 patients, the evaluation protocol and the results. Best results show that an average 80% Dice accuracy and a 1cm Hausdorff distance can be expected from semi-automated algorithms for this challenging task on the datasets, and that an automated algorithm can reach similar performance, at the expense of a high computational burden. Data are now publicly available and the website remains open for new submissions (http://www.litislab.eu/rvsc/).
ISSN: 1361-8415

hal-01141170
https://hal.archives-ouvertes.fr/hal-01141170
PUBMED : 25461337

Éditeur(s) : HAL CCSD
Résumé : International audience
The Kazdağ Massif exposes a metamorphic dome in the Biga Peninsula of northwest Turkey. An extensional origin has been proposed for the dome, limited on both flanks by detachments and/or shear zones. The northern flank is bounded by the extensional Alakeçi Shear Zone (ASZ), whose P-T-t path is still poorly known. We therefore focus on its metamorphic conditions and related temporal history to precise its tectono-metamorphic evolution. The local tectonostratigraphy in structurally ascending order comprises: (i) the high-grade metamorphic core rocks of the Kazdaǧ Massif (gneisses and micaschists intercalated with amphibolites and marbles); (ii) the two kilometer-thick ASZ; (iii) the overlaying unmetamorphosed pre-Cenomanian accretionary Çetmi mélange; and (iv) Neogene sedimentary and volcanic cover rocks. ASZ mylonites were derived from both the core rocks and the mélange lithologies. From the north to the south the mylonitic fabrics in the ASZ depict a top-to-the N-NNE shearing, parallel to the NNE-plunging stretching lineation and NNW-dipping mylonitic foliation. This geometry implies normal sense movement i.e. north-side down-dip extensional displacement along this flank of the Kazdaǧ Massif. The northward transition from ductile to brittle-ductile regime through the ASZ shows that the deformation occurred at decreasing temperatures and degree of metamorphism. The paragenesis in equilibrium within the mylonitic gneisses and schists contains Qtz + Fs + Ms + Bt + Grt ± St ± Sill, with late retrogressive chlorite after biotite and garnet. Four samples of ASZ rocks yielded pressures between 6.9-5.7 kbar and temperatures between 706-587°C. Three samples from the mylonitic rocks supplied in situ isochron 36Ar/40Ar mica ages between 31.2-24.2 Ma, which we interpret to date the cooling of the mylonites following the P-T decrease across the ASZ. The metamorphic and structural results support the extensional character of the ASZ, and sketch transition from sillimanite core gneisses in the deeper structural levels to chlorite schists towards the top of the shear zone. These new data allow to precise the peak P-T conditions and the temporal evolution in the northern flank of the Kazdaǧ Massif, where Late Oligocene extensional exhumation was assisted by NNE-directed ductile-brittle ASZ, which had operated from amphibolite to greenschist facies. At the regional scale, this tectono-metamorphic pattern is similar to those observed on other places of the north Aegean domain.
IOP Conference Series
Austin, TE, United States

hal-00642725
https://hal-brgm.archives-ouvertes.fr/hal-00642725
DOI : 10.1088/1755-1307/2/1/012012

Éditeur(s) : HAL CCSD Springer Verlag (Germany) Springer Verlag
Résumé : International audience
Replenished axial melt lenses at fast-spreading mid-oceanic ridges may move upward and intrude into the overlying hydrothermally altered sheeted dikes, resulting in high-grade contact metamorphism with the potential to trigger anatexis in the roof rocks. Assumed products of this process are anatectic melts of felsic composition and granoblastic, two-pyroxene hornfels, representing the residue after partial melting. Integrated Ocean Drilling Program Expeditions 309, 312, and 335 at Site 1256 (eastern equatorial Pacific) sampled such a fossilized oceanic magma chamber. In this study, we simulated magma chamber roof rock anatectic processes by performing partial melting experiments using six different protoliths from the Site 1256 sheeted dike complex, spanning a lithological range from poorly to strongly altered basalts to partially or fully recrystallized granoblastic hornfels. Results show that extensively altered starting material lacking primary magmatic minerals cannot reproduce the chemistry of natural felsic rocks recovered in ridge environments, especially elements sensitive to hydrothermal alteration (e.g., K, Cl). Natural geochemical trends are reproduced through partial melting of moderately altered basalts from the lower sheeted dikes. Two-pyroxene hornfels, the assumed residue, were reproduced only at low melting degrees (<20 vol%). The overall amphibole absence in the experiments confirms the natural observation that amphibole is not produced during peak metamorphism. Comparing experimental products with the natural equivalents reveals that water activity (aH2O) was significantly reduced during anatectic processes, mainly based on lower melt aluminum oxide and lower plagioclase anorthite content at lower aH2O. High silica melt at the expected temperature (1000–1050 °C; peak thermal overprint of two-pyroxene hornfels) could only be reproduced in the experimental series performed at aH2O = 0.1.
ISSN: 0010-7999

hal-01174139
https://hal.archives-ouvertes.fr/hal-01174139
DOI : 10.1007/s00410-015-1136-5

Éditeur(s) : HAL CCSD
Résumé : International audience
9th Joint Natural Products Conference
Copenhague, Denmark

hal-01627312
https://hal.archives-ouvertes.fr/hal-01627312

Éditeur(s) : Elsevier
Résumé : In biological modelling of the coastal phytoplankton dynamics, the light attenuation coefficient is often expressed as a function of the concentrations of chlorophyll and mineral suspended particulate matter (SPM). In order to estimate the relationship between these parameters over the continental shelf of the northern Bay of Biscay, a set of in situ data has been gathered for the period 1998-2003 when SeaWiFS imagery is available. These data comprise surface measurements of the concentrations of total SPM, chlorophyll, and irradiance profiles from which is derived the attenuation coefficient of the photosynthetically available radiation, K-PAR. The performance of the IFREMER look-up table used to retrieve the chlorophyll concentration from the SeaWiFS radiance is evaluated on this new set of data. The quality of the estimated chlorophyll concentration is assessed from a comparison of the variograms of the in situ and satellite-derived chlorophyll concentrations. Once the chlorophyll concentration is determined, the non living SPM, which is defined as the SPM not related to the dead or alive endogenous phytoplankton, is estimated from the radiance at 555 nm by inverting a semi-analytic model. This method provides realistic estimations of concentrations of chlorophyll and SPM over the continental shelf all over the year. Finally, a relationship, based on non living SPM and chlorophyll, is proposed to estimate K-PAR on the continental shelf of the Bay of Biscay. The same formula is applied to non living SPM and chlorophyll concentrations, observed in situ or derived from SeaWiFS radiance.
Remote Sensing of Environment (0034-4257) (Elsevier), 2005-03 , Vol. 95 , N. 1 , P. 29-46

Droits : 2004 Elsevier Inc. All rights reserved
http://archimer.ifremer.fr/doc/2005/publication-1172.pdf
DOI:10.1016/j.rse.2004.11.007
http://archimer.ifremer.fr/doc/00000/1172/

Éditeur(s) : HAL CCSD Geological Society of London
Résumé : International audience
Since the early descriptions published by Callaway in 1884, the gently dipping mylonites exposed along the Moine Thrust at the Stack of Glencoul have drawn generations of geologists to the northern part of the Assynt district. These mylonites, derived from Cambrian quartzites (footwall) and Moine pelites and psammites (hanging wall), have figured prominently in: a) early research into the influence of crystal plastic deformation and recrystallization on microstructural and crystal fabric evolution; b) debates on the kinematic interpretation of macro- and micro-structures and crystal fabrics; and c) debates on the tectonic significance of such kinematic data. In this paper first we briefly review the historical aspects of this research and then, using both previously published and unpublished data, document the finite strain and quartz fabric development at this classic mylonite locality. A tectonic interpretation of these data, together with quantitative estimates of flow vorticities associated with mylonite formation at the Stack of Glencoul, are presented in a companion paper by Law (2010).
Continental Tectonics and Mountain Building: The Legacy of Peach and Horne, Geological Society Speci

hal-00564962
https://hal.archives-ouvertes.fr/hal-00564962

Éditeur(s) : HAL CCSD American Academy of Neurology
Résumé : International audience
OBJECTIVE: We examined if the CNS Penetration-Effectiveness (CPE) score of antiretroviral drugs was associated with survival after a diagnosis of HIV-related encephalopathy, progressive multifocal leukoencephalopathy (PML), cerebral toxoplasmosis, or cryptococcal meningitis. METHODS: Using data from the FHDH-ANRS CO4, we compared the survival of 9,932 HIV-infected patients diagnosed with a first neurologic AIDS-defining event in the pre-combination antiretroviral therapy (cART) (1992-1995), early cART (1996-1998), or late cART (1999-2004) periods. Follow-up was subdivided (CPE < 1.5 and CPE ≥ 1.5), and relative rates (RR) of death were estimated using multivariable Poisson regression models. RESULTS: In the pre-cART and early cART periods, regimens with CPE ≥ 1.5 were associated with lower mortality after HIV-related encephalopathy (RR 0.64; 95% confidence interval [CI] 0.47-0.86 and RR 0.45; 95% CI 0.35-0.58) and after PML (RR 0.79; 95% CI 0.55-1.12 and RR 0.45; 95% CI 0.31-0.65), compared to regimens with CPE < 1.5, while in the late cART period there was no association between the CPE score and the mortality. A higher CPE score was also associated with a lower mortality in all periods after cerebral toxoplasmosis (RR 0.68, 95% CI 0.56-0.84) or cryptococcal meningitis (RR 0.50, 95% CI 0.34-0.74). Whatever the neurologic event, these associations were not maintained after adjustment on updated plasma HIV-RNA (missing, <500, ≥500 copies/mL) with RR ranging from 0.82 (95% CI 0.36-1.91) to 1.02 (0.69-1.52). CONCLUSION: At the beginning of the cART era, the CPE score was of importance for survival after severe neurologic event, while in the late cART period, the additional effect of CPE score vanished with more powerful antiretroviral regimens associated with plasma viral load control.
ISSN: 0028-3878

hal-00875434
https://hal.archives-ouvertes.fr/hal-00875434
DOI : 10.1212/WNL.0b013e31820c3089
PUBMED : 21248274