Résumé : En occupant un espace social privilégié, la médecine traditionnelle et les diverses pratiques qui y sont liées, sont de moins en moins marginalisées, de plus en plus admises comme ressources et la société leur devient du même coup permissive. La tolérance sociale est relativement forte ». Cette lecture de la situation de la médecine traditionnelle et de sa réception dans la société est celle de l’anthropologue et médecine martiniquais M. Yoyo. Elle évoque la réalité de la médecine créole dans l’espace antillais et dit l’intérêt que lui portent ceux qui en font usage.L’objectif de cette recherche est de poser la question de la transmission du savoir médicinal en contexte martiniquais : transmission des tradipraticiens vers les profanes ; transmission entre professionnels de cette médecine. Autrement dit comment se fait l’apprentissage si apprentissage il y a, de ce savoir traditionnel, jalousement gardé par ceux qui l’exercent ? La dimension magico-religieuse de ce savoir influe-t-elle sur sa transmission ? Quel est le rôle de la famille dans l’éducation et la transmission de ces pratiques ? Quelle est la connaissance profane accessible à tous et que détiennent certaines familles ? Celle-ci répond-elle aux attentes de la médecine traditionnelle et comment les familles procèdent-elles à sa transmission ? Quelle contribution l’institution scolaire apporte-t-elle à la sauvegarde de ce patrimoine ? Ce questionnement nous amène à nous interroger sur les pratiques en matière de médecine des Martiniquais et à considérer la coexistence entre savoir traditionnel et savoir rationnel dit moderne.On ne peut faire l’économie de ces analyses si on veut appréhender de façon objective le problème de la transmission de la médecine créole, de sa sauvegarde par – et pour – les générations montantes, en raison de l’aspect mémoriel de cette pratique thérapeutique mais également en raison de son efficacité et du potentiel important qu’elle représente pour la santé dans les années qui viennent.
By occupying a privileged social space, traditional medicine and the diverses practices related to the field are less and less marginalized, more and more accepted as resources, thus society is gradually becoming more tolerant towards those practices. The social tolerance is relatively strong”. This perception of the present situation of traditional medicine and of its reception in society is proposed by M. Yoyo, French anthropologist and physician from Martinique. It speaks of the reality of traditional medicine in the west Indians context and highlights the positive affects on those who make use of it. The objective of this research is to explore the question of the transmission of medicinal knowledge within the confines of Martinique: transmission by traditionalists towards nonprofessionals as well as transmission among professionals in the fields of medicine. In other words, what learning, if any, still exists of this traditional knowledge faithfully kept by those practiced it? To what extent does the magical-religious experience influence the transmission of this knowledge? What is the role of the family in the education and the transmission of those practices? How much of this profane knowledge is accessible to all and to what extent is it practiced by families? Does the latter respond to the demands of traditional medicine? How do families proceed with the process of transmission. What contribution does the school make towards preserving this tradition ? The above questions provoke reflection on the medicinal practices of the people of Martinique and of the possible coexistence of traditional knowledge and modern or rational knowledge. These questions are inevitable if we want to progress with objectivity in the transmission of Creole medicine and of its preservation for future generations, as a form of safeguarding the memory of this therapeutic practice. However, they also help to focus on the level of its effectiveness and the potential importance that it represents in ensuring a healthy environment in the coming years.

http://www.theses.fr/2015AGUY0865/document

Résumé : La première illustration d'une larve d'ombrine dans le milieu naturel est publié par Jannke en 1971. La description des oeufs et larves d'ombrine est réalisée par Holt (1981) . L'alimentation des larves d'ombrine dans le milieu naturel est précisée par Steen et Laroche (1983), (d'après Robinson, 1988). La croissance larvaire dans le golfe du Mexique est étudiée par Comyns et al, 1989. En 1978, Arnold et al., avec les premiers résultats obtenus sur le contrôle de la ponte de l'ombrine, effectuent les tous premiers essais d'élevage en intensif dont les résultats sont peu prometteurs par rapport à ceux obtenus d'après la technique d'élevage larvaire en extensif (Colura et al.,1976). Par la suite un certain nombre de paramètres de l'élevage en bassins vont être étudiés l'âge de 1ère alimentation, la charge et la concentration en larves (Roberts et al., 1978 - Holt & Arnold, 1985 , la croissance larvaire (Lee et al, 1984) , la température, la salinité et la tolérance à l'ammoniaque (Holt et al 1981 - Holt & Arnold, 1983). Une revue des connaissances sur l'élevage larvaire en "intensif" (quelques larves au litre) est réalisée par Holt & al (1987). Le travail présenté ici est très certainement l'étude la plus importante réalisée jusqu'à ce jour sur l'alevinage en intensif et en bassins de l'ombrine subtropicale. Il a comme objectif de démontrer la faisabilité technique de son élevage, et de promouvoir le développement de son aquaculture. Différents thèmes de recherche vont apparaître et s'imposer au cours des 3 années d'étude sur cette espèce, au fil des élevages successifs. Comme présenté sur le tableau 1, les larves utilisées en élevages sont issues de 14 lots, 9 importés des USA et 5 "locaux". Ces 14 lots ont permis la réalisation de 14 élevages larvaires "pilotes" en volume de bassins de 300, 1000, 1800 litres avec des volumes d'élevage de 2m3, 2-4m3 et- 2-10m3 pour les différentes phases de l'élevage Ces élevages "pilotes" visent à appliquer les connaissances zootechniques acquises sur l'espèce, à travers les expérimentations en volumes plus faibles (401, 2251, 5001) où des thèmes aussi divers que la lumière , l'abondance et la qualité des proies, le sevrage et le sevrage précoce, les normes zootechniques du prégrossissement ont été abordés (4éme document de cette étude). Les élevages 4,5,8,9 et 12 n'ont pu être menés à terme (tableau 1) . Les premiers essais de tri en élevage (tri précoce en écloserie et tri en prégrossissement), sont également présentés.

Droits : 1990 Ifremer
http://archimer.ifremer.fr/doc/00133/24381/22396.pdf
http://archimer.ifremer.fr/doc/00133/24381/

Éditeur(s) : HAL CCSD Maison de la géographie
Résumé : International audience
The location and history of theCaribbean Basin have undoubtedly favouredthe development of these spaces founded onthe principle of permanent exemption. Firsttolerated and then given legal status, theyplay a dual role : they are comparatively“unregulated”, but at the same time contri-bute to the regulation of the world system.But can this double game last in a preca-rious and instable international context?
La situación geográfica y la his-toria del Caribe favorecieron el desarrollo deespacios particulares, cimentados a partir delprincipio de la derogación permanente.Tolerados y luego legalizados, todos desem-peñan un doble papel, en distintos niveles : sonzonas en las cuales no se respeta el derecho yal mismo tiempo participan de la regulacióndel sistema-mundo. ¿Se puede seguir jugandocon dos barajas en un contexto internacionaltrastornado e inestable ?
La situation et l’histoire duBassin caraïbe ont incontestablement favo-risé le développement d’espaces fondés surle principe de la dérogation permanente.Tolérés puis légalisés, ils jouent un doublerôle : ils sont des zones de non-droit etcependant ils participent à la régulation dusystème monde. Ce double jeu peut-il néan-moins perdurer dans un monde ébranlé etinstable ?
ISSN: 1769-7298

hal-01172647
https://hal.archives-ouvertes.fr/hal-01172647

Éditeur(s) : HAL CCSD American Physiological Society
Résumé : International audience
The IL-33/ST2 axis plays a protective role in T-cell-mediated hepatitis, but little is known about the functional impact of endogenous IL-33 on liver immunopathology. We used IL-33-deficient mice to investigate the functional effect of endogenous IL-33 in concanavalin A (Con A)-hepatitis. IL-33(-/-) mice displayed more severe Con A liver injury than wild-type (WT) mice, consistent with a hepatoprotective effect of IL-33. The more severe hepatic injury in IL-33(-/-) mice was associated with significantly higher levels of TNF-alpha and IL-1 beta and a larger number of NK cells infiltrating the liver. The expression of Th2 cytokines (IL-4, IL-10) and IL-17 was not significantly varied between WT and IL-33(-/-) mice following Con A-hepatitis. The percentage of CD25(+) NK cells was significantly higher in the livers of IL-33(-/-) mice than in WT mice in association with upregulated expression of CXCR3 in the liver. Regulatory T cells (Treg cells) strongly infiltrated the liver in both WT and IL-33(-/-) mice, but Con A treatment increased their membrane expression of ST2 and CD25 only in WT mice. In vitro, IL-33 had a significant survival effect, increasing the total number of splenocytes, including B cells, CD4(+) and CD8(+) T cells, and the frequency of ST2(+) Treg cells. In conclusion, IL-33 acts as a potent immune modulator protecting the liver through activation of ST2(+) Treg cells and control of NK cells.
ISSN: 0193-1857

hal-01366372
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01366372
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01366372/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01366372/file/Ablation%20of%20interaction%20between%20IL-33%20and%201%20ST2.pdf
DOI : 10.1152/ajpgi.00097.2016

Éditeur(s) : HAL CCSD Springer Verlag (Germany)
Résumé : International audience
Mass bleaching events resulting in coral mortality are among the greatest threats to coral reefs, and are projected to increase in frequency and intensity with global warming. Achieving a better understanding of the consistency of the response of coral assemblages to thermal stress, both spatially and temporally, is essential to determine which reefs are more able to tolerate climate change. We compared variations in spatial and taxonomic patterns between two bleaching events at the scale of an island (Moorea Island, French Polynesia). Despite similar thermal stress and light conditions, bleaching intensity was significantly lower in 2007 (approximately 37 % of colonies showed signs of bleaching) than in 2002, when 55 % of the colonies bleached. Variations in the spatial patterns of bleaching intensity were consistent between the two events. Among nine sampling stations at three locations and three depths, the stations at which the bleaching response was lowest in 2002 were those that showed the lowest levels of bleaching in 2007. The taxonomic patterns of susceptibility to bleaching were also consistent between the two events. These findings have important implications for conservation because they indicate that corals are capable of acclimatization and/or adaptation and that, even at small spatial scales, some areas are consistently more susceptible to bleaching than others.
ISSN: 0167-6369

hal-00905944
https://hal.archives-ouvertes.fr/hal-00905944
DOI : 10.1007/s10661-012-2923-3

Éditeur(s) : EDP Sciences
Résumé : Martinique is a French overseas department whose economy relies heavily on agriculture. Organochlorine pesticides, mainly chlordecone, were used for banana cultivation to eradicate banana weevil over a period of 40 years. Chlordecone is chemically stable,and has a strong affinity for fatty tissues. It is therefore able to bioaccumulate in animals and thereby represent a threat to ecosystems and man. Soils from banana plantations in Martinique are heavily contaminated with chlordecone. Possible transfer of these molecules from agricultural watersheds to the aquatic environment and the organisms that live in it is feared. The hypothesis that ecosystems of Martinique might be highly contaminated with this organochlorine pesticide was investigated. Chlordecone levels were measured in various freshwater and marine species. Data show a heavy contamination of many carnivorous and detritivorous species (fish and prawns). Concentrations measured in wild or farmed tilapia are among the highest ever reported in the literature. Some coastal species (fish and lobster) were also found to be contaminated, although to a lesser extent. Given the biogeochemical behavior of chlordecone, the most likely route of contamination is food. Detected concentrations in marine organisms are below the tolerated limits established by authorities. however. the impact of other sources of exposure, namely, contaminated water and root vegetables, remains to be investigated.
Aquatic Living Resources (0990-7440) (EDP Sciences), 2006-04 , Vol. 19 , N. 2 , P. 181-187

Droits : EDP Sciences, IFREMER, IRD 2006
http://archimer.ifremer.fr/doc/2006/publication-1662.pdf
DOI:10.1051/alr:2006016
http://archimer.ifremer.fr/doc/00000/1662/

Éditeur(s) : HAL CCSD Oxford University Press (OUP): Policy B - Oxford Open Option B
Résumé : Variability of leaf traits related to photosynthesis was assessed in seedlings from 14 tree species growing in the tropical rain forest of French Guiana. Leaf photosynthetic capacity (maximum rate of carboxylation and maximum rate of electron transport) was estimated by fitting a biochemical model of photosynthesis to response curves of net CO2 assimilation rate versus intercellular CO2 mole fraction. Leaf morphology described by leaf mass per unit leaf area (LMA), density and thickness, as well as area- and mass-based nitrogen (N) and carbon (C) concentrations, were recorded on the same leaves. Large interspecific variability was detected in photosynthetic capacity as well as in leaf structure and leaf N and C concentrations. No correlation was found between leaf thickness and density. The correlations between area- and massbased leaf N concentration and photosynthetic capacity were poor. Conversely, the species differed greatly in relativeNallocation to carboxylation and bioenergetics. Principal component analysis (PCA) revealed that, of the recorded traits, only the computed fraction of total leafNinvested in photosynthesis was tightly correlated to photosynthetic capacity.We also used PCAto test to what extent species with similar shade tolerances displayed converging leaf traits related to photosynthesis. No clear-cut ranking could be detected among the shade-tolerant groups, as confirmed by a one-way ANOVA.We conclude that the large interspecific diversity in photosynthetic capacity was mostly explained by differences in the relative allocation of N to photosynthesis and not by leafNconcentration, and that leaf traits related to photosynthetic capacity did not discriminate shade-tolerance ranking of these tropical tree species.
ISSN: 0829-318X

hal-01031522
https://hal.archives-ouvertes.fr/hal-01031522

Éditeur(s) : HAL CCSD Springer Verlag
Résumé : International audience
Zelus annulosus is an assassin bug species mostly noted on Hirtella physophora, a myrmecophyte specifically associated with the ant Allomerus decemarticulatus known to build traps on host tree twigs to ambush insect preys. The Z. annulosus females lay egg clutches protected by a sticky substance. To avoid being trapped, the first three instars of nymphs remain grouped in a clutch beneath the leaves on which they hatched, yet from time to time, they climb onto the upper side to group ambush preys. Long-distance prey detection permits these bugs to capture flying or jumping insects that alight on their leaves. Like some other Zelus species, the sticky substance of the sundew setae on their forelegs aids in prey capture. Group ambushing permits early instars to capture insects that they then share or not depending on prey size and the hunger of the successful nymphs. Fourth and fifth instars, with greater needs, rather ambush solitarily on different host tree leaves, but attract siblings to share large preys. Communal feeding permits faster prey consumption, enabling small nymphs to return sooner to the shelter of their leaves. By improving the regularity of feeding for each nymph, it likely regulates nymphal development, synchronizing molting and subsequently limiting cannibalism.
ISSN: 0028-1042

hal-01091981
https://hal.archives-ouvertes.fr/hal-01091981
https://hal.archives-ouvertes.fr/hal-01091981/document
https://hal.archives-ouvertes.fr/hal-01091981/file/Dejean_11543.pdf
DOI : 10.1007/s00114-013-1091-9

Éditeur(s) : HAL CCSD American Society for Microbiology
Résumé : International audience
Under physiological conditions, the liver sinusoidal endothelial cells (LSECs) mediate hepatic immune tolerance toward self or foreign antigens through constitutive expression of anti-inflammatory mediators. However, upon viral infection or Toll-like receptor 2 (TLR2) activation, LSECs can achieve proinflammatory functions, but their role in hepatic inflammation during acute viral hepatitis is unknown. Using the highly virulent mouse hepatitis virus type 3 (MHV3) and the attenuated variants 51.6-MHV3 and YAC-MHV3, exhibiting lower tropism for LSECs, we investigated in vivo and in vitro the consequence of LSEC infection on their proinflammatory profiles and the aggravation of acute hepatitis process. In vivo infection with virulent MHV3, in comparison to attenuated strains, resulted in fulminant hepatitis associated with higher hepatic viral load, tissue necrosis, and levels of inflammatory mediators and earlier recruitment of inflammatory cells. Such hepatic inflammatory disorders correlated with disturbed production of interleukin-10 (IL-10) and vascular factors by LSECs. We next showed in vitro that infection of LSECs by the virulent MHV3 strain altered their production of anti-inflammatory cytokines and promoted higher release of proinflammatory and procoagulant factors and earlier cell damage than infection by attenuated strains. This higher replication and proinflammatory activation in LSECs by the virulent MHV3 strain was associated with a specific activation of TLR2 signaling by the virus. We provide evidence that TLR2 activation of LSCEs by MHV3 is an aggravating factor of hepatic inflammation and correlates with the severity of hepatitis. Taken together, these results indicate that preservation of the immunotolerant properties of LSECs during acute viral hepatitis is imperative in order to limit hepatic inflammation and damage. IMPORTANCE Viral hepatitis B and C infections are serious health problems affecting over 350 million and 170 million people worldwide, respectively. It has been suggested that a balance between protection and liver damage mediated by the host's immune response during the acute phase of infection would be determinant in hepatitis outcome. Thus, it appears crucial to identify the factors that predispose in exacerbating liver inflammation to limit hepatocyte injury. Liver sinusoidal endothelial cells (LSECs) can express both anti- and proinflammatory functions, but their role in acute viral hepatitis has never been investigated. Using mouse hepatitis virus (MHV) infections as animal models of viral hepatitis, we report for the first time that in vitro and in vivo infection of LSECs by the pathogenic MHV3 serotype leads to a reversion of their intrinsic anti-inflammatory phenotype toward a proinflammatory profile as well to as disorders in vascular factors, correlating with the severity of hepatitis. These results highlight a new virus-promoted mechanism of exacerbation of liver inflammatory response during acute hepatitis.
ISSN: 0022-538X

hal-01390974
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01390974
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01390974/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01390974/file/Mouse%20Hepatitis%20Virus%20Infection_accepted.pdf
DOI : 10.1128/JVI.01069-16

Éditeur(s) : HAL CCSD Cambridge University Press (CUP)
Résumé : Devil's gardens are one of the most remarkable mutualistic associations between ants and plants. Myrmelachista ants eliminate all vegetation from around their host plants, resulting in wide forest clearings which have intrigued scientists from the start. Despite their noticeability, here we report the discovery of devil's gardens in remote highland cloud forests of the Eastern Amazon, more than 2000 km away from their nearest known analogues in Western Amazonia. We describe the ecological characteristics of these gardens and consider what factors could have produced the geographic isolation of Eastern Amazonian devil's gardens. Three hypotheses are investigated: (1) the host plant distribution restricts the distribution of the mutualism, (2) the ecological tolerances of Myrmelachista explain the isolation, and (3) the devil's gardens of the Eastern Amazon constitute relicts from ancient forest refugia. The distribution of the possible associated myrmecophytes and previously described ecological ranges of devil's gardens cannot explain their ecological restriction to cloud forests in Eastern Amazonia, but our discovery is consistent with the biogeographic refuge hypothesis (i.e. highlands along the Amazon Basin constitute refugia for humid forests that spread during the Cenozoic). Our finding opens exciting perspectives for comparative studies of the origin, ecology and evolutionary history of this ant-plant mutualism.
ISSN: 0266-4674

hal-01532640
https://hal.archives-ouvertes.fr/hal-01532640
DOI : 10.1017/S0266467416000195
PRODINRA : 384619

Éditeur(s) : Cushman Foundation for Foraminiferal Research
Résumé : The objectives of this study were to observe foraminiferal colonization patterns and behavior in shrimp ponds in New Caledonia during a shrimp-growing (farming) cycle. Weekly collecting at 10 stations in 8 shrimp ponds yielded a total of 170 samples accompanied by environmental data. Seawater pumped from the nearby ocean filled the ponds at the beginning of the growth cycle and its daily renewal maintained salinity at 32-39, and supplied the ponds with influxes of smaller, mostly juvenile, foraminifera. A few days after initial filling, the pioneering species Ammonia tepida and Quinqueloculina seminula appeared, with A. tepida dominant. Their high reproduction rates increased both living and dead assemblage densities during the first 10 weeks. Populations of these two species then stabilized with higher oxygen demand (drop of redox) and consumption of living foraminifera by shrimp. Only a few colonizers subsequently appeared, which was attributed to the isolation of the pond, despite the high rate of water renewal. Only one pond had notably higher species richness, but it could not be distinguished from the others by its physicochemical parameters. The species that appeared in ponds initially barren of foraminifera also survived where there was water seepage between growing cycles, suggesting that the assemblages had already reached equilibrium with the environment. Despite the number of environmental parameters measured, only oxygen and reactive organic matter correlated with the microfauna on a weekly timescale. We assume that other parameters do not significantly affect foraminifera until they reach critical threshold. Consistent with previous studies, A. tepida was the species most tolerant of organic influx, but its relative abundance dropped once the organic matter flocculated and settled, leading to disoxic conditions in the sediment. Conversely, Q. seminula was able to climb through the floc and reach the oxygenated layer, where its relative abundance increased.
Journal of Foraminiferal Research (0096-1191) (Cushman Foundation for Foraminiferal Research), 2009-10 , Vol. 39 , N. 4 , P. 249-266

Droits : 2009 Cushman Foundation for Foraminiferal Research
http://archimer.ifremer.fr/doc/2009/publication-6954.pdf
DOI:10.2113/gsjfr.39.4.249
http://archimer.ifremer.fr/doc/00000/6954/

Éditeur(s) : Actes de colloques Ifremer, Tahiti, French Polynesia, 20 Feb - 4 Mar 1989, n°9, chap. 45, pp.486
Résumé : An overview of the methods of producing red drum are discussed. Although red drum culture is new compared to the culture of other species there is much interest in the production both in earthen ponds and in recirculating intensive systems. Various strategies for both methods will be discussed. This includes stocking rates, optimum growth, temperature, salinity and growth rates of red drum (Sciaenops ocellatus).

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1989/acte-1480.pdf
http://archimer.ifremer.fr/doc/00000/1480/

Éditeur(s) : HAL CCSD Nature Publishing Group
Résumé : International audience
The regulatory mechanisms involved in the acquisition of thermal tolerance are unknown in insects. Reversible phosphorylation is a widespread post-translational modification that can rapidly alter proteins function(s). Here, we conducted a large-scale comparative screening of phosphorylation networks in adult Drosophila flies that were cold-acclimated versus control. Using a modified SIMAC method followed by a multiple MS analysis strategy, we identified a large collection of phosphopeptides (about 1600) and phosphoproteins (about 500) in both groups, with good enrichment efficacy (80%). The saturation curves from the four biological replicates revealed that the phosphoproteome was rather well covered under our experimental conditions. Acclimation evoked a strong phosphoproteomic signal characterized by large sets of unique and differential phosphoproteins. These were involved in several major GO superclusters of which cytoskeleton organization, positive regulation of transport, cell cycle, and RNA processing were particularly enriched. Data suggest that phosphoproteomic changes in response to acclimation were mainly localized within cytoskeletal network, and particularly within microtubule associated complexes. This study opens up novel research avenues for exploring the complex regulatory networks that lead to acquired thermal tolerance.
ISSN: 2045-2322

hal-01532256
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01532256
DOI : 10.1038/s41598-017-01974-z
PUBMED : 28490779

Éditeur(s) : HAL CCSD
Résumé : International audience
Introduction: Diabetes mellitus results from the loss of tolerance to insulin and alters glycemia and the glycogen content. Oxidative stress and inflammation are linked to theses alterations, especially with insulin-resistance. The therapy management of diabetes includes nutritional recommendations. Several nutrients are developed to improve glycemia, oxidative stress, inflammation and glycogen content. More interestingly, ?-GOS exhibits anti-inflammatory and insulin-sensitive effects in vitro (Efstathiou and Fathi 2010) and in vivo (Boucher et al. 2003). Thus, ?-GOS is a potential functional food for the treatment of diabetes. But, less is known about the in vivo effect of ?-GOS on inflammatory, glycoxidation markers and glycogen content in diabetes. In this context, the aim of this work was to study the effect of ?-GOS developed by Sojasun technologies (from fermented soy product) compared to a synthetic ?-GOS produced by Sigma on inflammatory, glycoxidation markers and glycogen content in a streptozotocin-induced diabetic rat model. Methods: Twenty-four male Wistar streptozotocin-diabetic rat (STZ) were divided into three group: control group, supplemented with natural ?-GOS (20 mg/kg/day) group and supplemented with synthetic ?-GOS (20 mg/kg/day). The supplementation protocol duration was 8 weeks. At the end of the protocol, blood and skeletal muscle (gastrocnemius) were obtained to measure glucose , insulin, fructosamine in plasma and N-(carboxymethyl)lysine, glycogen synthase activity and glycogen content, in muscle. Results-Discussion: Diabetes was confirmed with the measure of insuline and glucose levels. All the diabetic groups had significantly higher glucose and insuline levels compared to control healthy group (data not shown). Insuline level in plasma and storage of glycogen in muscle were increased only in both ?-GOS groups. Fructosamine, TNF?and glycogen synthase activity was also decreased in the two supplemented groups (synthetic ?-GOS and natural ?-GOS). CML remained unchanged in all groups. Natural ?-OGT and synthetic ?-OGT only differed on muscular glucose level: only natural ?-OGT induced a significant decrease in muscular glucose. To conclude, our results suggest that ?-GOS alters positively glucose level, increases the glycogen content in diabetique population, improves glycemic control in the long term and decreases the inflammatory effects in streptozotocin-diabetic rat . Keywords: ?-GOS, inflammatory and glycoxidation markers, diabetes. Acknowledgment : Brittany region References Efstathiou, T. and D. Fathi. Sojasun Technologies. 2010 Boucher J et al. J Physiol Biochem. 59(3):169-73, 2003
5e congrès international de "Nutrition, Oxygen Biology and Medicine", Paris 5-7 juin 2013
Paris, France

hal-01159375
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01159375

Éditeur(s) : Actes de colloques Ifremer, Tahiti, French Polynesia, 20 Feb - 4 Mar 1989, n°9, chap. 46, pp.487-498
Résumé : The Caribbean Marine Research Centre is conducting research on the development of methods for intensive culture of euryhaline red tilapias in marine environments for application to Caribbean islands and similar regions with limited freshwater resources.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1989/acte-1493.pdf
http://archimer.ifremer.fr/doc/00000/1493/

Éditeur(s) : HAL CCSD School of Communications and Informatics
Résumé : International audience
The hybrid proximal point algorithm introduced by Solodov and Svaiter allowing significant relaxation of the tolerance requirements imposed on the solution of proximal subproblems will be combined with the inertial method introduced by Alvarez and Attouch which incorporates second order information to achieve faster convergence. The weak convergence of the resulting method will be investigated for finding zeroes of a maximal monotone operator in a Hilbert space.
ISSN: 1443-5756

hal-00780745
https://hal.univ-antilles.fr/hal-00780745
https://hal.univ-antilles.fr/hal-00780745/document
https://hal.univ-antilles.fr/hal-00780745/file/170_03_www.pdf

Éditeur(s) : Actes de colloques Ifremer, Tahiti, French Polynesia, 20 Feb - 4 Mar 1989, n°9, chap. 48, pp.511-516
Résumé : Hoplosternum littorale is a siluriform fish of very high commercial value in some countries of South America. Some biological characteristics as easy spawning in confinement and good tolerance of low oxygen level make it easy to cultivate.

Droits : info:eu-repo/semantics/openAccess
http://archimer.ifremer.fr/doc/1989/acte-1491.pdf
http://archimer.ifremer.fr/doc/00000/1491/

Éditeur(s) : HAL CCSD
Résumé : International audience
Decreased frequency of pulmonary exacerbations, mainly related to immunomodulatory effects of macrolide antibiotics, has been demonstrated in bronchiectasis and chronic obstructive pulmonary diseases (COPD). Due to its tolerance, azithromycin is the antibiotic of choice for maintenance therapy at the dose of 250 mg per day or 500 mg × 3 per week (for body weight extgreater55 kg). Maintenance therapy with macrolide could be proposed in selected patients with bronchiectasis or COPD with more than 3 acute exacerbations in the previous year or decreased lung function despite compliance with optimum treatment. The risk of sudden cardiac death with azithromycin is rare and controversial. It should be avoided in patients with a high baseline risk of cardiovascular disease, QT extgreater450 msec, pulse rate extgreater100 bpm and potential drug interactions, particularly those known to cause QT prolongation. It is recommended to search for hearing deficit (audiometry) and sputum culture positive for mycobacteria. Patients must also be aware that it can rapidly lead to macrolide resistance in commensal or pathogenic flora. Follow-up evaluation every 3 month can be proposed with medical history (hearing deficit) and electrocardiography. After one year, the treatment should be stopped in the absence of reduction in the frequency of exacerbations.
Presse Médicale (Paris, France: 1983)

hal-01063927
https://hal.archives-ouvertes.fr/hal-01063927
DOI : 10.1016/j.lpm.2013.08.006

Éditeur(s) : Styli 2003. Trente ans de crevetticulture en Nouvelle-Calédonie. Nouméa - Koné, 2-6 juin 2003. 2004. Gorarant C, Harache Y, Herbland A, Mugnier C. Ed. Ifremer, Actes de Colloque, n°38, pp.113-120
Résumé : Two oyster species are currently present along the French coasts : the indigenous European flat oyster (Ostrea edulis), and the Pacific cupped oyster (Crassostrea gigas), that has been introduced from Japan since the beginning of the 70ies. The flat oyster successively suffered from two protozoan diseases during the 60ies and its production decreased from 20 000 tons/year by that time to 1 500 tons/year nowadays. Consequently, the oyster production is principally (99%) based upon the Pacific oyster species with approximately 150 000 tons/year among which 90% are grown from the natural spat. However, the hatchery production of this species is developing and was estimated to 400 to 800 millions spat in 2002. Moreover, strengthened relationships between IFREMER and the 5 commercial hatcheries, that all joined the SYSAAF (Union of the French poultry, shellfish and fish farming selectors), allow to plan for new genetic breeding programs. At the end of the 80ies, IFREMER initiated a genetic breeding program for the resistance of the European flat oyster to the bonamiosis, and obtained strains more tolerant to this disease. After two generations of massal selection, molecular markers had identified a reduced genetic basis in this program. It was then reoriented to an intra-familial selection. However, we were confronted to a zootechnic problem to manage such a scheme and we compromised by an intra-cohorts of families selection scheme managed using molecular markers. The program has now reached the transfer level with experimentation at a professional scale. Concerning the Pacific cupped oyster, and in parallel with the obtaining and the study of polyploids, performance of different Asian cupped oyster strains were compared to the one introduced in France thirty years ago and currently suffering from summer mortalities. The local strain exhibited better performance, certainly based upon a good local adaptation. In other respects, although early growth is a relevant criteria for selection for growth to commercial stage, it is not to be privileged in the context of an oyster producing region with a limited food availability. Contrary, the spat summer mortality became a priority for numerous teams (genetic, physiology, pathology, ecology,...) joined in the MOREST program. The first results showed important survival differences between fullsib and halsib families. They indicate a genetic determinism to this character "survival" and promote for its selection.
Deux espèces d'huîtres sont aujourd'hui présentes sur les côtes françaises : l'huître plate européenne (Ostrea edulis), indigène, et l'huître creuse du Pacifique (Crassostrea gigas), introduite du Japon dans le début des années 1970. L'huître plate a subi coup sur coup, dans les années 1960, deux maladies dues à des protozoaires parasites et sa production est ainsi passée de 20 000 t/an dans les années 1960 à 1500 t/an aujourd'hui en France. Il en résulte que la filière ostréicole française repose quasiment exclusivement (99%) sur la production de l'huître creuse, C. gigas, avec 150 000 tonnes en 2000 dont environ 90% est issu du captage naturel. Cependant, la reproduction de cette espèce en écloserie est actuellement en expansion avec une estimation de 400 à 800 millions de naissains commercialisés en 2002. Des rapports renforcés entre l'IFREMER et les cinq écloseries françaises de la filière ostréicole, qui adhèrent toutes au SYSAAF (SYndicat des Sélectionneurs Avicoles et Aquacoles Français), permettent désormais d'envisager le développement de nouveaux programmes d'amélioration génétique. A la fin des années 1980, un programme de sélection pour la résistance de l'huître plate à la bonamiose a été initié au sein de l'IFREMER, et a permis d'obtenir des souches plus tolérantes à cette maladie. Après deux générations en sélection massale, les marqueurs moléculaires avaient mis en évidence une base génétique réduite au sein de ce programme qui s'était alors orienté vers une sélection intra-familiale. Devant la lourdeur zootechnique d'un tel schéma, un compromis a été trouvé en réalisant une sélection au sein de cohortes de familles biparentales, la gestion de ces cohortes étant permise par les analyses moléculaires. Le programme est maintenant dans sa phase de transfert, avec des expérimentations à plus grande échelle en partenariat avec la profession. En ce qui concerne l'huître creuse, et en parallèle de l'obtention et l'étude de polyploïdes, les performances de différentes souches d'huîtres creuses provenant d'Asie ont été comparées à celles de la souche introduite en France il y a trente ans, sujette à des mortalités estivales. La souche locale présente de meilleures performances, vraisemblablement grâce à une adaptation bien réalisée. Par ailleurs, bien que l'amélioration de la croissance jusqu'à la taille commerciale s'avère possible par une sélection précoce au stade larvaire, le critère de croissance n'est pas nécessairement à privilégier dans le contexte d'un bassin ostréicole disposant de ressources trophiques limitées. En revanche, les importantes mortalités rencontrées par le naissain en périodes estivales constituent le sujet d'étude prioritaire sur lequel se sont penchées de nombreuses équipes (génétique, physiologie, pathologie, écologie, ...) dans le cadre du grand défi MOREST. Les premiers résultats ont mis en évidence de fortes différences de survie entre des familles biparentales d'animaux indiquant un déterminisme génétique du caractère « survie », et encourageant dans la voie d'une sélection pour ce caractère.

Droits : 2004 Ifremer
http://archimer.ifremer.fr/doc/2003/acte-3491.pdf
http://archimer.ifremer.fr/doc/00000/3491/

Éditeur(s) : HAL CCSD Elsevier
Résumé :  
absent
Ecology management of a neotropical rainforest: lessons drawn from Paracou, a long-term experimental research site in French Guiana

ISBN : 2-84299-455-8
hal-01190858
https://hal.archives-ouvertes.fr/hal-01190858
PRODINRA : 70132